CN104338091A - 治疗痤疮、青春痘的药物及其制备方法 - Google Patents

治疗痤疮、青春痘的药物及其制备方法 Download PDF

Info

Publication number
CN104338091A
CN104338091A CN201310310653.5A CN201310310653A CN104338091A CN 104338091 A CN104338091 A CN 104338091A CN 201310310653 A CN201310310653 A CN 201310310653A CN 104338091 A CN104338091 A CN 104338091A
Authority
CN
China
Prior art keywords
radix
medicine
comedo
drug
rhizoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201310310653.5A
Other languages
English (en)
Inventor
陈学媛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201310310653.5A priority Critical patent/CN104338091A/zh
Publication of CN104338091A publication Critical patent/CN104338091A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/37Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

本发明提供一种治疗痤疮、青春痘的药物及其制备方法,其原料药组分包括柴胡、当归、白芍、炒白术、茯苓、薄荷、生姜、炙甘草、桑白皮、牛膝、香附11味中药材,并提供其制备方法。本发明是传世秘方与现代药典相结合,是传统汤药改变而成的新一代制品,主治痤疮、青春痘。经几代人的研究及临床观察显示,该药物对皮脂腺管与毛孔的堵塞所致的痤疮、青春痘等症均有切实疗效。

Description

治疗痤疮、青春痘的药物及其制备方法
技术领域
本发明涉及一种治疗痤疮、青春痘的药物,具体地说属于以中草药为原料的中成药,本发明还涉及该药物的制备方法。
背景技术
痤疮、青春痘是现在生活中男女最为常见的一种皮肤性疾病,能造成人体皮肤上皮脂腺或毛囊的发炎,局部病变时会产生能挤出白色或乳白色碎米样粉汁的刺状丘疹。目前常用的治疗方法有抗生素疗法、激素疗法等西医疗法,但是抗生素疗法、激素疗法等西医疗法治表不治本,而且会产生副作用。
发明内容
本发明针对上述不足,从临床医疗用药需求及中医组方辩证原则出发,所选用的中药物质量上乘稳定,使药品质量达到“安全、有效、稳定、可靠”。依据祖传秘方结合现代治疗方法,提供一种主治痤疮、青春痘的配伍组合药物及其制造方法。能迅速深入肌肤深处,促进细胞分裂再生,激发细胞活力,从根本上解决皮脂分泌旺盛的现象,愈合面皰伤口,消炎杀菌,无痕除去暗疮,让肌肤嫩白光滑,紧致无痕。
本发明所述的药物是由下列重量份数配比的原料制备成的药剂:
柴胡6-15份、当归6-15份、白芍6-15份、炒白术6-15份、茯苓6-15份、薄荷6-15份、生姜6-15份、炙甘草6-15份、桑白皮6-15份、牛膝6-15份、香附6-15份。
优选配方:
柴胡8-12份、当归8-12份、白芍8-12份、炒白术8-12份、茯苓8-12份、薄荷8-12份、 生姜8-12份、炙甘草8-12份、桑白皮8-12份、牛膝8-12份、香附8-12份。 
以上药方指的是克,比如香附8-12份也就是指8-12克,每一付药的总重量是110克。
有益效果:本发明是传世秘方与现代药典相结合,是传统汤药改变而成的新一代制品,主治痤疮、青春痘。经几代人的研究及临床观察显示该药物对皮脂腺管与毛孔的堵塞所致的痤疮、青春痘等症均有切实疗效。
具体实施方式
实施例1                                                           
按下述配比(重量份)称取原料:
柴胡6-15份、当归6-15份、白芍6-15份、炒白术6-15份、茯苓6-15份、薄荷6-15份、生姜6-15份、炙甘草6-15份、桑白皮6-15份、牛膝6-15份、香附6-15份。
以上药方份指的是克,比如香附6-15份也就是指6-15克,每一付药的总重量是110克。
制备方法如下:
(1)取方中柴胡、当归、白芍、炒白术、茯苓、薄荷、生姜、炙甘草、桑白皮、牛膝、香附粉碎与筛析;
(2)将步骤(1)中筛制的混合物加水煎煮2-3次,合并煎液、过滤、滤液浓缩成80度时相对密度为1.0-1.6的稠膏;
(3)将稠膏分离纯化、干燥,制成颗粒;
(4)将步骤(3)中的干颗粒混匀,填充胶囊内即制得胶囊剂;将步骤(3)中的干颗粒喷加炼蜜、混匀,制成小丸即制成丸剂;将(3)步骤的干颗粒压制成片剂,包糖衣,即制成片剂。
实施例2
按下述配比(重量份)称取原料:
柴胡8-12份、当归8-12份、白芍8-12份、炒白术8-12份、茯苓8-12份、薄荷8-12份、 生姜8-12份、炙甘草8-12份、桑白皮8-12份、牛膝8-12份、香附8-12份。
以上药方指的是克,比如香附8-12份也就是指8-12克,每一付药的总重量是110克。
制备方法如下: 
(1)取方中柴胡、当归、白芍、炒白术、茯苓、薄荷、生姜、炙甘草、桑白皮、牛膝、香附粉碎与筛析。
(2)将步骤(1)中筛制的混合物加水煎煮2-3次,合并煎液、过滤、滤液浓缩成80度时相对密度为1.0-1.6的稠膏;
(3)将稠膏分离纯化、干燥,制成颗粒;
(4)将步骤(3)中的干颗粒混匀,填充胶囊内即制得胶囊剂;将步骤(3)中的干颗粒喷加炼蜜、混匀,制成小丸即制成丸剂;将(3)步骤的干颗粒压制成片剂,包糖衣,即制成片剂。
实施例3
实施1、2任何一个实施例中制备方法步骤(2)中所述的混合物,均适用加水煎煮次数为2次,第一次为60分钟,第二次为40分钟。

Claims (5)

1.一种治疗痤疮、青春痘的药物,其特征在于它是由下列重量份数配比的原料制备成的药剂:柴胡6-15份、当归6-15份、白芍6-15份、炒白术6-15份、茯苓6-15份、薄荷6-15份、生姜6-15份、炙甘草6-15份、桑白皮6-15份、牛膝6-15份、香附6-15份。
2.根据权利要求1所述的治疗痤疮、青春痘的药物,其特征在于其中各原料的重量份数配比为:柴胡8-12份、当归8-12份、白芍8-12份、炒白术8-12份、茯苓8-12份、薄荷8-12份、 生姜8-12份、炙甘草8-12份、桑白皮8-12份、牛膝8-12份、香附8-12份。
3. 根据权利要求1或2所述的治疗痤疮、青春痘的药物,其特征在于:所述药剂为胶囊、丸剂或片剂。
4.根据权利要求3所述的治疗痤疮、青春痘的药物,其特征在于制备方法步骤如下:
(1)取方中柴胡、当归、白芍、炒白术、茯苓、薄荷、生姜、炙甘草、桑白皮、牛膝、香附粉碎与筛析;
(2)将步骤(1)中筛制的混合物加水煎煮2-3次,合并煎液、过滤、滤液浓缩成80度时相对密度为1.0-1.6的稠膏;
(3)将稠膏分离纯化、干燥,制成颗粒;
(4)将步骤(3)中的干颗粒混匀,填充胶囊内即制得胶囊剂;将步骤(3)中的干颗粒喷加炼蜜、混匀,制成小丸即制成丸剂;将(3)步骤的干颗粒压制成片剂,包糖衣,即制成片剂;将(3)步骤的干颗粒压制成片剂,包糖衣,即制成片剂。
5.根据权利要求4所述的治疗痤疮、青春痘的药物的制备方法,其特征在于:步骤(2)中所述的混合物加水煎煮次数为2次,第一次为60分钟,第二次为40分钟。
CN201310310653.5A 2013-07-23 2013-07-23 治疗痤疮、青春痘的药物及其制备方法 Pending CN104338091A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310310653.5A CN104338091A (zh) 2013-07-23 2013-07-23 治疗痤疮、青春痘的药物及其制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310310653.5A CN104338091A (zh) 2013-07-23 2013-07-23 治疗痤疮、青春痘的药物及其制备方法

Publications (1)

Publication Number Publication Date
CN104338091A true CN104338091A (zh) 2015-02-11

Family

ID=52495082

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310310653.5A Pending CN104338091A (zh) 2013-07-23 2013-07-23 治疗痤疮、青春痘的药物及其制备方法

Country Status (1)

Country Link
CN (1) CN104338091A (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110403870A (zh) * 2019-08-27 2019-11-05 广东工业大学 一种含中药提取物的肤用化妆品及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102406765A (zh) * 2011-12-01 2012-04-11 荣成市科学技术情报研究所 一种治疗痤疮的中药组合物
CN102688315A (zh) * 2012-06-27 2012-09-26 杨万明 一种治疗痤疮的药物及其制备方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102406765A (zh) * 2011-12-01 2012-04-11 荣成市科学技术情报研究所 一种治疗痤疮的中药组合物
CN102688315A (zh) * 2012-06-27 2012-09-26 杨万明 一种治疗痤疮的药物及其制备方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
张沛崧: "清肝达郁汤治疗妇女面部痤疮30例", 《新中医》 *
陈吉棠等: "丹栀逍遥散加甲氯酊治疗痤疮197例临床观察", 《浙江中西医结合杂志》 *
韩慧: "袁红霞应用逍遥散经验", 《山东中医杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110403870A (zh) * 2019-08-27 2019-11-05 广东工业大学 一种含中药提取物的肤用化妆品及其制备方法

Similar Documents

Publication Publication Date Title
CN101129817B (zh) 一种治疗高血压的中药制剂及其制备方法
CN104337974A (zh) 治疗崩漏的药物及其制备方法
CN104922543A (zh) 一种治疗闭经的药物组合物及其制备方法
CN100478020C (zh) 治疗口腔溃疡的药物
CN104338044A (zh) 治疗妇科白带异常的药物及其制备方法
CN102872363B (zh) 一种治疗贫血的中药口服液
CN102727779A (zh) 一种治疗卵巢囊肿的药物组合物及其制备方法
CN102416145B (zh) 一种治疗月经失调的中药组合物
CN102657736B (zh) 一种治疗类风湿性关节炎的药物组合物及其制备方法
CN102631437B (zh) 一种治疗风湿痹痛的药物及其制备方法
CN104173546A (zh) 治疗鼻炎的中药水
CN1351872A (zh) 一种治疗粉刺痤疮的中药
CN102204978B (zh) 一种治疗癌性疼痛的药物组合物及其制剂
CN104225507A (zh) 一种治疗脑溢血所致的肢体麻痹和疼痛的中药
CN101596270B (zh) 一种用于治疗慢性咽炎的药物及其制备方法
CN103550688A (zh) 一种治疗心悸的中药组合物
CN104338091A (zh) 治疗痤疮、青春痘的药物及其制备方法
CN101856423A (zh) 一种治疗月经不调的药物及其制备方法
CN102552729A (zh) 治疗系膜增生性肾小球肾炎的药物
CN102552520A (zh) 一种治疗胸痹心痛的活血止痛药物及制备工艺和应用
CN101816774A (zh) 养血调经祛斑散
CN104056017A (zh) 治疗内风湿的中药组合物及其制剂和制备方法
CN102284023A (zh) 一种治疗喘症的中药组合物
CN102366594A (zh) 一种用于调节月经的中药
CN102430026A (zh) 祛斑药物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20150211

RJ01 Rejection of invention patent application after publication