CN104338074A - 一种消瘀接骨药膏贴及其制备方法 - Google Patents
一种消瘀接骨药膏贴及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种消瘀接骨药膏贴及其制备方法，包括胶贴片和涂覆在胶贴片上的药膏，所述的药膏主要由以下重量份数的原料制成：丹参20-40份，当归6-12份，龙爪叶12-19份，自然铜10-15份，血竭18-26份，姜黄6-12份，地鳖虫6-9份，三七40-65份，荆芥8-15份，王不留行9-18份，油280-360份，凡士林290-350份，酒300-380份。与现有技术相比，本发明的有益效果是：本发明为天然成分组合而成，其组方科学、不需要上夹板、打石膏等任何人工固定方式，减轻了病人的痛苦，同时也减轻了病人的经济负担；愈合期短、见效快；可缩短疗程。
Description
技术领域
本发明属于重要技术领域，涉及一种治疗跌打损伤、骨折筋断的药物组合物，尤其涉及一种消瘀接骨药膏贴及其制备方法。
背景技术
骨折主要是指由外伤引起的骨结构的连续性被部分或完全断裂的一种疾病，是常见外科疾病。多见于儿童及老年人，中青年人也时有发生。病人常为一个部位骨折，少数为多发性骨折。它给受伤者带来巨大痛苦，轻则数月，重则年余甚至更久不能恢复。
骨折迟缓愈合或久不愈合时有发生严重影响患者的生活及劳动能力。骨折的愈合是指骨折断端间的组织修复反应。新生修复的过程是由膜内骨化与软骨内骨化共同完成的。骨折愈合的过程也是由暂时性紧急连接过渡到永久的坚固连接过程，是一个连续不断的过程。
目前，西医多采用手术治疗，一般都是采用先将骨折部位扶正后再用钢丝、夹板等器具对骨折部位进行固定，然后用石膏、绷带固定。这种方法主要依靠患者自身再生能力使骨折部位自然接合，或配合服用一些活血化瘀、消炎止痛类药物。这种治疗方法的缺点是其治疗周期长，费用高，骨质生长慢、治疗周期长，同时骨折部位容易出现不同程度的重叠移位，致使肿胀疼痛加剧，造成伸屈功能减弱或丧失，患者十分痛苦。
经及时恰当处理，如复位、固定、功能锻炼，多数病人能恢复原来的功能，少数病人可遗留有不同程度的后遗症。但是现有治疗骨折的药物，存在止痛消肿慢、疗程长，效果不理想等缺点，患者需要忍受长时间的疼痛，需要改进。
申请号为201410099217.2的中国专利公开了一种发明名称为“一种接骨药及制备方法”的发明专利，该接骨药，主要由下列原料制各而成，均为重量份:骨粉460重量份、鹿茸2重量份、自然铜(锻)92重量份、乳香92重量份、没药55重量份、红花46重量份、血竭18重量份、莪术55重量份、骨碎补230重量份、续断230重量份、土鳖虫92重量份、丹参230重量份、当归184重量份；其中，所述骨粉为由狗骨、花蕊石、石膏经百草烧制后混合形成的混合物。同时该发明专利还公开了接骨药的制备方法，包括以下步骤如下：将狗骨、花蕊石、石膏用经百草焙烧，焙烧后狗骨成灰白，花蕊石、石膏多次烧制、烧透成灰黑色，将焙烧后狗骨、花蕊石、石膏砸碎，混匀，制成粗粉，过40目筛；取莪术、骨碎补、续断、乳香、没药加水浸泡1小时后，煎煮2次，第一次1.5小时，第二次1小时;合并煎液，滤过，滤液浓缩后备用；取红花、土鳖虫、丹参、当归，与骨粉、鹿茸、自然铜(锻)、血竭研成细末，过80目筛，并混匀； 取上述浓缩液泛丸，60℃烘干，选丸，经环氧乙烷灭菌，放置7-10天后即得所述接骨药。
申请号201310550873.5的中国专利公开了一种发明名称为“接骨中药及其制备方法”的发明专利，该接骨中药主要由以下重量份数的原料药制成：蒲公英10-15份、荆芥4.5-9份、麻黄2-9份、丹参5-15份、龙爪叶9-15份、鹅掌藤6-18份、接骨草9-15份、没药10-20份、乳香5-15份、桃仁4.5-9份、红花3-10份、姜黄3-10份、王不留行5-10份、凌霄花5-10份、枫香脂3-6份、臭梧桐10-20份、寻骨风10-20份、接骨木10-20份。该发明专利还公开了接骨中药的制备方法，包括以下步骤：将上述原料药碾成粉末，混合均匀，然后将粉末与菜籽油、凡士林混合制成膏状物。声称治疗效果好。
发明内容
本发明需要解决的上述问题是针对上述现有技术的不足，而提供一种消瘀接骨药膏贴及其制备方法。
为解决上述技术问题，本发明采用的技术方案是：
一种消瘀接骨药膏贴，包括胶贴片和涂覆在胶贴片上的药膏，所述的药膏主要由以下重量份数的原料制成：丹参20-40份，当归6-12份，龙爪叶12-19份，自然铜10-15份，血竭18-26份，姜黄6-12份，地鳖虫6-9份，三七40-65份，荆芥8-15份，王不留行9-18份，油280-360份，凡士林290-350份，酒300-380份。
作为优选，所述的药膏主要由以下重量份数的原料制成：
丹参20份，当归6份，龙爪叶12份，自然铜10份，血竭18份，姜黄6份，地鳖虫6份，三七40份，荆芥8份，王不留行9份，油280份，凡士林290份，酒300份。
作为优选，所述的药膏主要由以下重量份数的原料制成：
丹参40份，当归12份，龙爪叶19份，自然铜15份，血竭26份，姜黄12份，地鳖虫9份，三七65份，荆芥15份，王不留行18份，油360份，凡士林350份，酒380份。
作为优选，所述的药膏主要由以下重量份数的原料制成：
丹参30份，当归11份，龙爪叶15份，自然铜13份，血竭23份，姜黄9份，地鳖虫7份，三七54份，荆芥14份，王不留行16份，油320份，凡士林325份，酒360份。
作为优选，所述的油为菜油。
作为优选，所述的酒为米酒。
上述的消瘀接骨药膏贴的制备方法，将上述各原料晒干后碾成粉末，并混合均匀，然后将上述混合粉末与加热后微凉的油、酒和凡士林中调成膏状，然后再把膏状物涂覆在胶贴片上
本发明接骨膏药贴的各原料功效如下：
丹参，味苦，性微寒。能活血化瘀，凉血，安神。能扩张冠状动脉，增加冠脉流量，改善心肌缺血、梗塞和心脏功能，调节心律，并能扩张外周血管，改善微循环；能提高机体耐缺氧能力；有抗凝血，促进纤溶，抑制血小板凝聚，抑制血栓形成的作用；能降低血脂，抑制冠脉粥样硬化形成；能抑制或减轻肝细胞变性、坏死及炎症反应，促进肝细胞再生，并有抗纤维化作用；用于血淤所致月经不调、痛经、经闭，产后淤滞腹痛；冠心病心绞痛，动脉粥样硬化；慢性肝炎、肝硬化，腹腔包块或肿瘤；慢性肺心病，支气管哮喘：血不养心或心火偏亢，心悸不安，心烦失眠。
当归，伞形科植物当归的干燥根。性温，味甘，具有补血和活血，祛风散寒，排脓之痛。
龙爪叶，性味归经:苦，温。入肺、肾、肝、脾四经。功效:舒筋活络，行气祛湿，散寒祛风，祛湿止泻。主治:用于跌打损伤、骨折疼痛者，寒湿瘀阻的痛痹，外感风寒，发热畏寒、头身疼痛。用于腹部胀满，全身乏力，不思饮食、纳差，痢疾者。
自然铜，味辛苦，性平，散瘀止痛，接骨续筋。
血竭，棕搁科植物麒麟竭果实渗出的树脂，性平，味咸，有散瘀定痛，生肌止血的功效。
姜黄，性味：味苦；辛；性温。归经：脾经；肝经。功效：破血行气；通经止痛。主治：血瘀气滞诸证；胞腹胁痛；妇女痛经；闭经；产后瘀滞腹痛；风湿痹痛；跌打损伤；痈肿。
地鳖虫，为鳖蠊科昆虫地鳖或冀地鳖的雌虫干燥体。捕捉后，置沸水中烫死，晒干或烘干。性味与归经：咸，寒；有小毒。归肝经。功能与主治：破瘀血，续筋骨。用于筋骨折伤，瘀血经闭，症瘕痞块，用于血瘀经闭、跌打损伤及症瘕肿块；
散瘀止痛：用于血瘀引起的肝脾肿痛及腰肌劳损、扭伤。
三七，性温，味辛，具有散淤止血，消肿定痛的功效。
荆芥，性味:味辛；微苦；性微湿。①《本经》:味辛，温。②《医学启源》:气温，味辛苦。归经:入肺、肝经。主治:解表散风，透疹，消疮，止血。用于感冒，麻疹透发不畅，便血、崩漏。功效与作用:祛风；解表；透疹；止血。主感冒发热；头痛；目痒；咳嗽；咽喉肿痛；麻疹；痈肿；疮疥；吐血；便血；崩漏；产后血晕。用于感冒，头痛，麻疹，风疹，疮疡初起。炒炭治便血，崩漏，产后血晕。
王不留行，性味归经：苦，平。归肝，胃经。功效：行血调经、消肿止痛、活血通乳、催生下乳、产后胸腺疏通。主治：血瘀经闭，痛经，难产；产后乳汁不下，乳痈肿痛；热淋，血淋，石淋。
中医理论认为:骨折创伤必然引起体内经络、血气以及脏腑功能紊乱，造成血气俱伤，营卫脏腑不和，经络阻遏，骨髓、骨膜和周围组织及血运破坏，因此，在治疗上应遵循调理气血经络，消肿止痛，活血祛瘀，同时兼用补气行血、生血养血，从而达到活血化瘀，快速续筋接骨的目的。
与现有技术相比，本发明的有益效果是：
1、本发明为天然植物药、矿物药、动物药组合而成，其组方科学、配伍合理，无毒副作用与不良反应。
2、不需要上夹板、打石膏、负担捆扎等任何人工固定方式，减轻了病人的痛苦，同时也减轻了病人的经济负担。
3、本发明愈合期短、见效快。使用本药后不久即可明显止痛，临床实践证明与传统治疗方法相比可缩短疗程。
4、本发明是在土法秘方的基础上，又经临床应用改进，治愈率极高。
具体实施方式
现在对本发明作进一步详细的说明。
实施例1
一种消瘀接骨药膏贴，包括胶贴片和涂覆在胶贴片上的药膏，所述的药膏主要由以下重量份数的原料制成：丹参20份，当归6份，龙爪叶12份，自然铜10份，血竭18份，姜黄6份，地鳖虫6份，三七40份，荆芥8份，王不留行9份，菜油280份，凡士林290份，米酒300份。
制备方法：
上述的消瘀接骨药膏贴的制备方法，将上述各原料晒干后碾成粉末，并混合均匀，然后将上述混合粉末与加热后微凉的菜油、米酒和凡士林中调成膏状，然后再把膏状物涂覆在胶贴片上
实施例2
一种消瘀接骨药膏贴，包括胶贴片和涂覆在胶贴片上的药膏，所述的药膏主要由以下重量份数的原料制成：丹参40份，当归12份，龙爪叶19份，自然铜15份，血竭26份，姜黄12份，地鳖虫9份，三七65份，荆芥15份，王不留行18份，菜油360份，凡士林350份，米酒380份。
制备方法：
上述的消瘀接骨药膏贴的制备方法，将上述各原料晒干后碾成粉末，并混合均匀，然后将上述混合粉末与加热后微凉的菜油、米酒和凡士林中调成膏状，然后再把膏状物涂覆在胶贴片上
实施例3
一种消瘀接骨药膏贴，包括胶贴片和涂覆在胶贴片上的药膏，所述的药膏主要由以下重量份数的原料制成：丹参30份，当归11份，龙爪叶15份，自然铜13份，血竭23份，姜黄9份，地鳖虫7份，三七54份，荆芥14份，王不留行16份，菜油320份，凡士林325份，米酒360份。
制备方法：
上述的消瘀接骨药膏贴的制备方法，将上述各原料晒干后碾成粉末，并混合均匀，然后将上述混合粉末与加热后微凉的菜油、米酒和凡士林中调成膏状，然后再把膏状物涂覆在胶贴片上
治疗结果：
本发明人与2006年至今对734例门诊患者进行临床观察治疗，年龄从3岁到90岁不等，男女数量基本相等。
治疗方法为：将上述膏药贴贴于患处，一个疗程为2-3天。
疗效评定标准：
治愈：症状体征完全消失；
有效：症状体征较前减轻；
无效：症状体征与治疗前无改善。
治疗效果：
| 病例数 | 734 |
| 治愈数 | 725 |
| 有效数 | 9 |
| 无效数 | 0 |
| 治愈率 | 98.7% |
| 总有效率 | 100% |
以上述依据本发明的理想实施例为启示，通过上述的说明内容，相关工作人员完全可以在不偏离本项发明技术思想的范围内，进行多样的变更以及修改。本项发明的技术性范围并不局限于说明书上的内容，必须要根据权利要求范围来确定其技术性范围。
Claims (7)
1.一种消瘀接骨药膏贴，包括胶贴片和涂覆在胶贴片上的药膏，其特征在于：所述的药膏主要由以下重量份数的原料制成：丹参20-40份，当归6-12份，龙爪叶12-19份，自然铜10-15份，血竭18-26份，姜黄6-12份，地鳖虫6-9份，三七40-65份，荆芥8-15份，王不留行9-18份，油280-360份，凡士林290-350份，酒300-380份。
2. 根据权利要求1所述的消瘀接骨药膏贴，其特征在于：所述的药膏主要由以下重量份数的原料制成：丹参20份，当归6份，龙爪叶12份，自然铜10份，血竭18份，姜黄6份，地鳖虫6份，三七40份，荆芥8份，王不留行9份，油280份，凡士林290份，酒300份。
3. 根据权利要求1所述的消瘀接骨药膏贴，其特征在于：所述的药膏主要由以下重量份数的原料制成：丹参40份，当归12份，龙爪叶19份，自然铜15份，血竭26份，姜黄12份，地鳖虫9份，三七65份，荆芥15份，王不留行18份，油360份，凡士林350份，酒380份。
4. 根据权利要求1所述的消瘀接骨药膏贴，其特征在于：所述的药膏主要由以下重量份数的原料制成：丹参30份，当归11份，龙爪叶15份，自然铜13份，血竭23份，姜黄9份，地鳖虫7份，三七54份，荆芥14份，王不留行16份，油320份，凡士林325份，酒360份。
5. 根据权利要求1所述的消瘀接骨药膏贴，其特征在于：所述的油为菜油。
6. 根据权利要求1所述的消瘀接骨药膏贴，其特征在于：所述的酒为米酒。
7. 根据权利要求1所述的消瘀接骨药膏贴的制备方法，其特征在于：将上述各原料晒干后碾成粉末，并混合均匀，然后将上述混合粉末与加热后微凉的油、酒和凡士林中调成膏状，然后再把膏状物涂覆在胶贴片上。
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