CN104334742A - 解析和定量无细胞rna的方法 - Google Patents
解析和定量无细胞rna的方法 Download PDFInfo
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- CN104334742A CN104334742A CN201380017554.6A CN201380017554A CN104334742A CN 104334742 A CN104334742 A CN 104334742A CN 201380017554 A CN201380017554 A CN 201380017554A CN 104334742 A CN104334742 A CN 104334742A
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
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- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
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- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
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- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F18/00—Pattern recognition
- G06F18/20—Analysing
- G06F18/21—Design or setup of recognition systems or techniques; Extraction of features in feature space; Blind source separation
- G06F18/213—Feature extraction, e.g. by transforming the feature space; Summarisation; Mappings, e.g. subspace methods
- G06F18/2135—Feature extraction, e.g. by transforming the feature space; Summarisation; Mappings, e.g. subspace methods based on approximation criteria, e.g. principal component analysis
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810084289.8A CN108359711A (zh) | 2012-01-27 | 2013-01-28 | 解析和定量无细胞rna的方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261591642P | 2012-01-27 | 2012-01-27 | |
| US61/591,642 | 2012-01-27 | ||
| PCT/US2013/023471 WO2013113012A2 (en) | 2012-01-27 | 2013-01-28 | Methods for profiling and quantitating cell-free rna |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810084289.8A Division CN108359711A (zh) | 2012-01-27 | 2013-01-28 | 解析和定量无细胞rna的方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104334742A true CN104334742A (zh) | 2015-02-04 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380017554.6A Pending CN104334742A (zh) | 2012-01-27 | 2013-01-28 | 解析和定量无细胞rna的方法 |
| CN201810084289.8A Pending CN108359711A (zh) | 2012-01-27 | 2013-01-28 | 解析和定量无细胞rna的方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810084289.8A Pending CN108359711A (zh) | 2012-01-27 | 2013-01-28 | 解析和定量无细胞rna的方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (15) | US20130252835A1 (https=) |
| EP (2) | EP2807277A4 (https=) |
| JP (2) | JP6320302B2 (https=) |
| CN (2) | CN104334742A (https=) |
| AU (1) | AU2013211850B8 (https=) |
| CA (1) | CA2863035C (https=) |
| HK (1) | HK1211624A1 (https=) |
| SG (2) | SG11201505515XA (https=) |
| WO (1) | WO2013113012A2 (https=) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108369612A (zh) * | 2015-11-04 | 2018-08-03 | 梅塔博隆股份有限公司 | 自动化样品质量评估 |
| WO2018210275A1 (en) * | 2017-05-16 | 2018-11-22 | The Chinese University Of Hong Kong | Integrative single-cell and cell-free plasma rna analysis |
| US10155986B2 (en) | 2012-01-27 | 2018-12-18 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for profiling and quantitating cell-free RNA |
| CN111566228A (zh) * | 2017-10-23 | 2020-08-21 | 陈扎克伯格生物中心公司 | 用于在胎儿孕育中预测胎龄和早产的无创分子钟 |
| CN112424372A (zh) * | 2019-01-24 | 2021-02-26 | Illumina公司 | 用于监测器官健康和疾病的方法和系统 |
| US11773447B2 (en) | 2014-11-14 | 2023-10-03 | Nanthealth Labs, Inc. | Use of circulating cell-free RNA for diagnosis and/or monitoring cancer |
| US11845988B2 (en) | 2019-02-14 | 2023-12-19 | Mirvie, Inc. | Methods and systems for determining a pregnancy-related state of a subject |
| US12565679B2 (en) | 2012-01-27 | 2026-03-03 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for profiling and quantitating cell-free RNA |
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| RU2565550C2 (ru) | 2010-09-24 | 2015-10-20 | Те Борд Оф Трастиз Оф Те Лилэнд Стэнфорд Джуниор Юниверсити | Прямой захват, амплификация и секвенирование днк-мишени с использованием иммобилизированных праймеров |
| WO2015069900A1 (en) * | 2013-11-06 | 2015-05-14 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for profiliing and quantitating cell-free rna |
| US10689652B2 (en) | 2013-10-02 | 2020-06-23 | The Regents Of The University Of California | Methods for immortalization of epithelial cells |
| WO2015069933A1 (en) * | 2013-11-06 | 2015-05-14 | The Board Of Trustees Of The Leland Stanford Junior University | Circulating cell-free dna for diagnosis of transplant rejection |
| JP7451070B2 (ja) * | 2013-11-07 | 2024-03-18 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | ヒトミクロビオームおよびその成分の分析のための無細胞核酸 |
| CN107002122B (zh) | 2014-07-25 | 2023-09-19 | 华盛顿大学 | 确定导致无细胞dna的产生的组织和/或细胞类型的方法以及使用其鉴定疾病或紊乱的方法 |
| CN107922971A (zh) | 2015-05-18 | 2018-04-17 | 凯锐思公司 | 用于富集核酸群体的组合物和方法 |
| US10889861B2 (en) * | 2015-06-17 | 2021-01-12 | The Translational Genomics Research Institute | Systems and methods for obtaining biological molecules from a sample |
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| CN110964800B (zh) * | 2019-09-20 | 2021-10-22 | 北京航空航天大学 | 用于预测早产风险的cfRNA标志物 |
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