CN104330346B - 用于声学流式细胞计量术的方法 - Google Patents

用于声学流式细胞计量术的方法 Download PDF

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CN104330346B
CN104330346B CN201410492244.6A CN201410492244A CN104330346B CN 104330346 B CN104330346 B CN 104330346B CN 201410492244 A CN201410492244 A CN 201410492244A CN 104330346 B CN104330346 B CN 104330346B
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granule
sample
fluid
flow
acoustics
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CN104330346A (zh
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G·卡达查克
M·D·沃德
J·A·布莱德弗德
A·T·G·帕克
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Life Technologies Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • G01N21/453Holographic interferometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • G01N2015/142Acoustic or ultrasonic focussing

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  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
CN201410492244.6A 2009-12-04 2010-11-29 用于声学流式细胞计量术的方法 Active CN104330346B (zh)

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US26690709P 2009-12-04 2009-12-04
US61/266,907 2009-12-04
US30393810P 2010-02-12 2010-02-12
US61/303,938 2010-02-12
US35931010P 2010-06-28 2010-06-28
US61/359,310 2010-06-28
CN201080061774.5A CN102762990B (zh) 2009-12-04 2010-11-29 用于声学流式细胞计量术的装置、系统、方法和计算机可读介质

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EP (1) EP2507639B1 (enExample)
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Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7340957B2 (en) * 2004-07-29 2008-03-11 Los Alamos National Security, Llc Ultrasonic analyte concentration and application in flow cytometry
US7835000B2 (en) * 2006-11-03 2010-11-16 Los Alamos National Security, Llc System and method for measuring particles in a sample stream of a flow cytometer or the like
EP2156178B1 (en) * 2007-04-02 2011-12-21 Acoustic Cytometry Systems, Inc. Methods for enhanced analysis of acoustic field focused cells and particles
US7837040B2 (en) 2007-04-09 2010-11-23 Los Alamos National Security, Llc Acoustic concentration of particles in fluid flow
US8083068B2 (en) 2007-04-09 2011-12-27 Los Alamos National Security, Llc Apparatus for separating particles utilizing engineered acoustic contrast capture particles
US8263407B2 (en) 2007-10-24 2012-09-11 Los Alamos National Security, Llc Method for non-contact particle manipulation and control of particle spacing along an axis
US8528406B2 (en) * 2007-10-24 2013-09-10 Los Alamos National Security, LLP Method for non-contact particle manipulation and control of particle spacing along an axis
US9451884B2 (en) 2007-12-13 2016-09-27 Board Of Trustees Of The University Of Arkansas Device and method for in vivo detection of clots within circulatory vessels
US9144383B2 (en) 2007-12-13 2015-09-29 The Board Of Trustees Of The University Of Arkansas Device and method for in vivo noninvasive magnetic manipulation of circulating objects in bioflows
US20090156932A1 (en) 2007-12-13 2009-06-18 Board Of Trustees Of The University Of Arkansas Device and method for in vivo flow cytometry using the detection of photoacoustic waves
US8266950B2 (en) 2007-12-19 2012-09-18 Los Alamos National Security, LLP Particle analysis in an acoustic cytometer
US8714014B2 (en) 2008-01-16 2014-05-06 Life Technologies Corporation System and method for acoustic focusing hardware and implementations
US8658734B2 (en) * 2009-05-11 2014-02-25 Stc.Unm Synthesis of stable elastomeric negative acoustic contrast particles
AU2010326180B2 (en) * 2009-12-04 2015-06-18 Life Technologies Corporation Apparatuses, systems, methods, and computer readable media for acoustic flow cytometry
JP5437148B2 (ja) * 2010-04-23 2014-03-12 ベイバイオサイエンス株式会社 フローサイトメータおよびセルソータ
RU2587328C2 (ru) 2010-05-05 2016-06-20 БЕКМАН КАУЛТЕР БАЙОМЕДИКАЛ, ЭлЭлСи Диагностическая система и компоненты
WO2012098287A1 (en) * 2011-01-19 2012-07-26 Teknologian Tutkimuskeskus Vtt Method and system for determining particle size information
USD698038S1 (en) 2011-03-03 2014-01-21 Life Technologies Corporation Plate loader
JP5973471B2 (ja) 2011-03-03 2016-08-23 ライフ テクノロジーズ コーポレーション サンプリングプローブ、システム、装置、および方法
WO2013003498A2 (en) * 2011-06-27 2013-01-03 Life Technologies Corporation Acoustic cytometry methods and protocols
EP2594334A1 (en) 2011-11-21 2013-05-22 Drive O2 Sample vial for digital holographic analysis of a liquid cell sample
WO2013011001A1 (en) 2011-07-19 2013-01-24 Ovizio Imaging Systems N.V. A method and system for detecting and/or classifying cancerous cells in a cell sample
EP2761291B1 (en) * 2011-09-28 2016-06-29 Acousort AB System and method to separate cells and/or particles
EP2626686A1 (en) 2012-02-13 2013-08-14 Ovizio Imaging Systems NV/SA Flow cytometer with digital holographic microscope
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
US9950282B2 (en) 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US10967298B2 (en) 2012-03-15 2021-04-06 Flodesign Sonics, Inc. Driver and control for variable impedence load
JP6110484B2 (ja) * 2012-06-21 2017-04-05 エスティーシー. ユーエヌエムStc.Unm ラインフォーカシング式光源で励起した多数のサンプル流れからの空間相関集光
EP2898310B1 (en) 2012-09-20 2019-05-01 Ovizio Imaging Systems NV/SA Digital holographic microscope with fluid systems
CA2884954A1 (en) 2012-09-25 2014-04-03 Mark S. Smeltzer Device and method for in vivo photoacoustic diagnosis and photothermal purging of infected blood
WO2014062719A2 (en) * 2012-10-15 2014-04-24 Nanocellect Biomedical, Inc. Systems, apparatus, and methods for sorting particles
US10662408B2 (en) 2013-03-14 2020-05-26 Inguran, Llc Methods for high throughput sperm sorting
US10371622B2 (en) 2013-03-14 2019-08-06 Inguran, Llc Device for high throughput sperm sorting
US9757726B2 (en) 2013-03-14 2017-09-12 Inguran, Llc System for high throughput sperm sorting
CA3026548C (en) 2013-04-15 2022-01-04 Becton, Dickinson And Company Medical device for collection of a biological sample
CA2909367C (en) * 2013-04-15 2019-01-08 Becton, Dickinson And Company Biological fluid separation device and biological fluid separation and testing system
US9645080B2 (en) * 2013-04-16 2017-05-09 University Of Washington Systems, devices, and methods for separating, concentrating, and/or differentiating between cells from a cell sample
DK3004838T3 (da) 2013-05-28 2022-06-20 Chemometec As Billeddannende cytometer
US10126220B2 (en) * 2013-07-22 2018-11-13 National Oilwell Varco, L.P. Systems and methods for determining specific gravity and minerological properties of a particle
US9535000B2 (en) * 2013-09-05 2017-01-03 Bio-Rad Laboratories, Inc. On-demand particle dispensing system
US9963693B2 (en) 2013-10-21 2018-05-08 Biomet Biologics, Llc Cell washing device using a wave
US9725710B2 (en) 2014-01-08 2017-08-08 Flodesign Sonics, Inc. Acoustophoresis device with dual acoustophoretic chamber
US9377400B2 (en) 2014-03-31 2016-06-28 Redshift Systems Corporation Motion modulation fluidic analyzer system
KR20170039250A (ko) 2014-08-28 2017-04-10 시스멕스 가부시키가이샤 입자 촬상 장치 및 입자 촬상 방법
SG11201702571RA (en) * 2014-10-01 2017-04-27 Water Optics Technology Pte Ltd A sensor for particle detection in a fluid
CN111948015B (zh) 2014-10-24 2023-10-10 生命科技股份有限公司 以声学方式沉淀的液-液样品纯化系统
JP6646298B2 (ja) * 2014-12-16 2020-02-14 国立大学法人 東京大学 ロープ状構造体の製造方法
WO2016100954A1 (en) * 2014-12-19 2016-06-23 Captl Llc Flow cytometry using hydrodynamically planar flow
EP4278979A3 (en) 2014-12-31 2024-02-21 BioVentures, LLC Devices and methods for fractionated photoacoustic flow cytometry
US11959907B2 (en) * 2015-01-12 2024-04-16 Instrumentation Laboratory Company Spatial separation of particles in a particle containing solution for biomedical sensing and detection
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11021699B2 (en) 2015-04-29 2021-06-01 FioDesign Sonics, Inc. Separation using angled acoustic waves
WO2016181968A1 (ja) * 2015-05-13 2016-11-17 株式会社エアレックス パーティクル制御方法
JP6713730B2 (ja) 2015-05-20 2020-06-24 シスメックス株式会社 細胞検出装置および細胞検出方法
US10036698B2 (en) 2015-06-19 2018-07-31 Captl Llc Time-sequential cytometry
US11459540B2 (en) 2015-07-28 2022-10-04 Flodesign Sonics, Inc. Expanded bed affinity selection
US11474085B2 (en) 2015-07-28 2022-10-18 Flodesign Sonics, Inc. Expanded bed affinity selection
WO2017054839A1 (en) * 2015-09-28 2017-04-06 Siemens Healthcare Gmbh A technique for aligning a non-spherical biological entity in a flow cell
US10823657B2 (en) * 2015-12-23 2020-11-03 Siemens Healthcare Gmbh Flow cell for analyzing particles in a liquid to be examined
US10648900B2 (en) * 2015-12-23 2020-05-12 Becton, Dickinson And Company Multi-color flow cytometric analysis of samples with low cell numbers
EP3196631A1 (en) 2016-01-19 2017-07-26 Ovizio Imaging Systems NV/SA Digital holographic microscope with electro-fluidic system, said electro-fluidic system and methods of use
US11085035B2 (en) 2016-05-03 2021-08-10 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
FR3051556A1 (fr) * 2016-05-18 2017-11-24 Biocytex Utilisation de marqueurs fluorescents pour la detection de cible biologique dans un echantillon
JP7026063B2 (ja) * 2016-07-01 2022-02-25 ライフ テクノロジーズ コーポレーション 粒子を濃縮するための方法、システム、および装置
EP3493907B1 (en) * 2016-08-02 2023-10-04 IMEC vzw Method and arrangement for focusing objects in a flow
EP3300804B1 (en) * 2016-09-30 2020-04-08 ARKRAY, Inc. Method for separating particles, separation apparatus, and separation system
JP2020513248A (ja) 2016-10-19 2020-05-14 フロデザイン ソニックス, インク.Flodesign Sonics, Inc. 音響による親和性細胞抽出
US10436697B2 (en) 2016-11-19 2019-10-08 Cytek Biosciences, Inc. Flow cytometery system with fluidics control system
EP4390369A3 (en) 2016-11-19 2025-01-01 Cytek Biosciences, Inc. Flow cytometry systems with stepper flow control valve
CN106556561A (zh) * 2016-11-28 2017-04-05 中国科学院苏州生物医学工程技术研究所 一种流体粒子运动控制装置
CN106872339A (zh) * 2017-01-10 2017-06-20 中国科学院苏州生物医学工程技术研究所 一种粒子排序方法及其装置和用途
WO2018147462A1 (ja) * 2017-02-10 2018-08-16 東ソー株式会社 粒子検出装置及び粒子検出方法
KR102585276B1 (ko) 2017-03-31 2023-10-05 라이프 테크놀로지스 코포레이션 이미징 유세포 분석을 위한 장치, 시스템, 및 방법
CN107202773B (zh) * 2017-06-01 2019-07-05 重庆大学 一种利用聚苯乙烯球的细胞周期散射光强模型建立方法
CN111491555B (zh) 2017-10-16 2024-06-21 麻省理工学院 用于非侵入性血液测量的系统、装置和方法
DE102017126128A1 (de) 2017-11-08 2019-05-09 Endress+Hauser SE+Co. KG System und Verfahren zur ortsaufgelösten Bestimmung von zumindest einer physikalischen oder chemischen Prozessgröße
US10785574B2 (en) 2017-12-14 2020-09-22 Flodesign Sonics, Inc. Acoustic transducer driver and controller
WO2019119368A1 (zh) * 2017-12-21 2019-06-27 深圳先进技术研究院 一种声驱动的流式细胞检测装置
CN109946217B (zh) * 2017-12-21 2021-08-24 深圳先进技术研究院 一种声驱动的流式细胞检测装置
CN108120665A (zh) * 2017-12-28 2018-06-05 无锡奥芬光电科技有限公司 单色结构光检查微小颗粒的方法及设备
CN108444897B (zh) * 2018-03-06 2021-04-13 山东大学 基于光片照明与鞘流技术的免标记微流控细胞仪及方法
US11698364B2 (en) 2018-06-27 2023-07-11 University Of Washington Real-time cell-surface marker detection
CN112805548B (zh) 2018-10-30 2025-03-11 贝克顿·迪金森公司 具有对准窗口的颗粒分选模块、系统及其使用方法
CN109540771B (zh) * 2018-12-18 2020-12-08 武汉大学 一种精准分选白细胞亚型的声光微流控芯片及其分选方法
US11788965B2 (en) * 2019-02-21 2023-10-17 Arizona Board Of Regents On Behalf Of Arizona State University Folic acid functionalized copper sulfide nanoparticles for the detection of ovarian cancer cells in flow
US20220178811A1 (en) * 2019-04-18 2022-06-09 Fundació Institute De Ciències Fotòniques Opto-Fluidic Apparatus for Individual Interrogation of Organisms
JP2022531934A (ja) * 2019-05-15 2022-07-12 フロデザイン ソニックス, インク. 音響エッジ効果
US11160492B2 (en) 2019-07-24 2021-11-02 Massachusetts Institute Of Technology Finger inserts for a nailfold imaging device
JP7729538B2 (ja) * 2019-12-29 2025-08-26 アプライド セルズ インク 生物学的実体を分離するための方法および装置
CN115699108A (zh) 2020-05-28 2023-02-03 露科实验室股份有限公司 一种从无创性毛细血管视频中检测白细胞和/或白细胞亚型的方法
EP4162254A4 (en) * 2020-06-03 2024-06-05 Kinetic River Corp. CONFIGURABLE PARTICLE ANALYZER DEVICES AND METHODS
JP7042301B2 (ja) * 2020-06-04 2022-03-25 シスメックス株式会社 細胞検出方法
CN117203519A (zh) * 2020-11-25 2023-12-08 希里斯公司 用于个人化医疗和药物开发的微器官球体(micro-organosphere)
EP4086607B1 (en) * 2021-05-07 2024-12-04 Deutsches Elektronen-Synchrotron DESY Device and system for bunching of sample particles
CN119101655A (zh) * 2024-10-09 2024-12-10 上海交通大学 一种基于单波束聚焦声场三维空间捕获细胞方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2739572A1 (en) * 1999-12-03 2001-06-07 Xy, Llc Improved flow cytometer nozzle and flow cytometer sample handling methods

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284412A (en) * 1979-07-13 1981-08-18 Ortho Diagnostics, Inc. Method and apparatus for automated identification and enumeration of specified blood cell subclasses
US4298836A (en) * 1979-11-23 1981-11-03 Coulter Electronics, Inc. Particle shape determination
JPS61153546A (ja) * 1984-12-26 1986-07-12 Canon Inc 粒子解析装置
JPS61159135A (ja) * 1984-12-31 1986-07-18 Canon Inc 粒子解析装置
JPS62207933A (ja) * 1986-03-08 1987-09-12 Canon Inc 粒子解析装置
US4786165A (en) * 1986-07-10 1988-11-22 Toa Medical Electronics Co., Ltd. Flow cytometry and apparatus therefor
JPH0449573Y2 (enExample) * 1987-08-28 1992-11-20
JPH0277636A (ja) * 1988-09-13 1990-03-16 Canon Inc 粒子測定装置
JP3052665B2 (ja) * 1993-01-26 2000-06-19 株式会社日立製作所 フローセル装置
JPH07270301A (ja) * 1994-03-31 1995-10-20 Hitachi Ltd フロー式粒子画像解析方法およびその装置
JP3375203B2 (ja) * 1994-08-08 2003-02-10 シスメックス株式会社 細胞分析装置
JPH08297121A (ja) * 1995-04-26 1996-11-12 Hitachi Ltd 粒子分析装置
JPH09126989A (ja) * 1995-11-07 1997-05-16 Hitachi Ltd フロー式粒子画像解析装置
US5895869A (en) * 1995-11-17 1999-04-20 Mwi, Inc. Method and apparatus for analyzing particulate matter
GB9707096D0 (en) * 1997-04-08 1997-05-28 Smithkline Beecham Plc Novel device
US6074879A (en) * 1997-06-23 2000-06-13 Bayer Corporation Synthetic polymer particles for use as standards and calibrators in flow cytometry
US5880474A (en) * 1997-08-29 1999-03-09 Becton Dickinson And Company Multi-illumination-source flow particle analyzer with inter-location emissions crosstalk cancelation
US5895764A (en) * 1997-11-24 1999-04-20 University Of New Mexico Controlled sheath flow injection cytometry
US6067157A (en) * 1998-10-09 2000-05-23 University Of Washington Dual large angle light scattering detection
US6473171B1 (en) * 1999-01-15 2002-10-29 Coors Brewing Company Biocompatible apparatus for ultrasensitive and rapid detection of contaminants in liquids
US6249341B1 (en) * 1999-01-25 2001-06-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6890487B1 (en) * 1999-09-30 2005-05-10 Science & Technology Corporation ©UNM Flow cytometry for high throughput screening
US20020102595A1 (en) * 2001-01-29 2002-08-01 Davis Lloyd Mervyn Methods for detection of incorporation of a nucleotide onto a nucleic acid primer
US6467350B1 (en) * 2001-03-15 2002-10-22 The Regents Of The University Of California Cylindrical acoustic levitator/concentrator
JP2004535572A (ja) * 2001-06-13 2004-11-25 ケニス エフ. ウーヘンハイマー, 自動化流体操作システムおよび方法
US20030110840A1 (en) * 2001-07-24 2003-06-19 Arriaga Edgar A. Systems and methods for detecting a particle
US7201875B2 (en) * 2002-09-27 2007-04-10 Becton Dickinson And Company Fixed mounted sorting cuvette with user replaceable nozzle
US7340957B2 (en) * 2004-07-29 2008-03-11 Los Alamos National Security, Llc Ultrasonic analyte concentration and application in flow cytometry
EP2156178B1 (en) * 2007-04-02 2011-12-21 Acoustic Cytometry Systems, Inc. Methods for enhanced analysis of acoustic field focused cells and particles
US7837040B2 (en) * 2007-04-09 2010-11-23 Los Alamos National Security, Llc Acoustic concentration of particles in fluid flow
US8083068B2 (en) * 2007-04-09 2011-12-27 Los Alamos National Security, Llc Apparatus for separating particles utilizing engineered acoustic contrast capture particles
US8266950B2 (en) * 2007-12-19 2012-09-18 Los Alamos National Security, LLP Particle analysis in an acoustic cytometer
US8714014B2 (en) * 2008-01-16 2014-05-06 Life Technologies Corporation System and method for acoustic focusing hardware and implementations
US20100009333A1 (en) * 2008-07-08 2010-01-14 Beckman Coulter, Inc. Methods for Acoustic Particle Focusing in Biological Sample Analyzers
AU2010326180B2 (en) * 2009-12-04 2015-06-18 Life Technologies Corporation Apparatuses, systems, methods, and computer readable media for acoustic flow cytometry

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2739572A1 (en) * 1999-12-03 2001-06-07 Xy, Llc Improved flow cytometer nozzle and flow cytometer sample handling methods

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AU2010326180B2 (en) 2015-06-18
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US20180067044A1 (en) 2018-03-08
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CN104330346A (zh) 2015-02-04
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AU2010326180A1 (en) 2012-07-12
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