CN104324178A - Traditional Chinese medicine ointment for treating mosquito bite and preparation method of ointment - Google Patents
Traditional Chinese medicine ointment for treating mosquito bite and preparation method of ointment Download PDFInfo
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- CN104324178A CN104324178A CN201410560670.9A CN201410560670A CN104324178A CN 104324178 A CN104324178 A CN 104324178A CN 201410560670 A CN201410560670 A CN 201410560670A CN 104324178 A CN104324178 A CN 104324178A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention belongs to the field of traditional Chinese medicines, and discloses traditional Chinese medicine ointment for treating mosquito bite. The ointment is prepared from the following components in parts by weight: 3-7 parts of red bean zymolyte, 4-9 parts of spina gleditsiae alcohol extract, 3-6 parts of camphor water extract, 4-8 parts of areca-nut powder, 6-12 parts of vaseline and 5-10 parts of starch. The preparation method comprises the steps of carrying out enzymolysis, extracting, centrifuging, concentrating, stirring and filling. The prepared traditional Chinese medicine ointment has the characteristics of remarkable curative effect and quick response when used for treating mosquito bite.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicinal ointment and preparation method thereof, particularly relate to a kind of Chinese medicinal ointment for the treatment of mosquito bite and preparation method thereof.
Background technology
Should be smeared if there is the red and swollen phenomenon in local the ointment that some have antiinflammatory, antipruritic, analgesic activity by after mosquito bite, if the vesicle risen is scratched, then should smear the ointment of a little detumescence, pain relieving class, heavier or have the patient of secondary infection for symptom, the antiinflammatory of oral administration antibiotic, clean and sterilize by the local bitten in time simultaneously, smearing erythromycin ointment etc. in right amount.Herba Portulacae stem and leaf treatment mosquito bite in there is good effect, by Herba Portulacae to subsequently generation juice after, embrocate affected part, there is relieving itching and eliminating swelling effect.Realgar, Bulbus Allii in addition, obliterating at mosquito bite place, every day 1 ~ 2 time, can detoxify, ease pain, antipruritic, detumescence.Olibanum, Myrrha, Radix Angelicae Sinensis, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Radix Rehmanniae Preparata, Radix Saposhnikoviae, Flos Lonicerae, lavandula angustifolia etc. are treated and prevent mosquito bite aspect also to have good effect.
Summary of the invention
The technical problem solved: the symptoms such as red and swollen can be formed on skin after mosquito bite, the responding time of medicine in treatment mosquito bite of conventional treatment mosquito bite is longer, have impact on the actual impression of patient, and containing certain chemical composition in the medicine of the treatment mosquito bite of routine, harmful, therefore need the Chinese medicinal ointment of a kind of pure natural, instant effect, eutherapeutic treatment mosquito bite.
Technical scheme: for above-mentioned problem, the invention discloses a kind of Chinese medicinal ointment for the treatment of mosquito bite, and the Chinese medicinal ointment of described treatment mosquito bite comprises the composition of following weight parts:
Semen Phaseoli zymolyte 3 ~ 7 parts,
Spina Gleditsiae ethanol extract 4 ~ 9 parts,
Camphor water extract 3 ~ 6 parts,
Areca powder 4 ~ 8 parts,
6 ~ 12 parts, vaseline,
Starch 5 ~ 10 parts.
Described a kind of Chinese medicinal ointment for the treatment of mosquito bite, preferably includes the composition of following weight parts:
Semen Phaseoli zymolyte 4 ~ 6 parts,
Spina Gleditsiae ethanol extract 5 ~ 7 parts,
Camphor water extract 4 ~ 5 parts,
Areca powder 6 ~ 7 parts,
7 ~ 10 parts, vaseline,
Starch 6 ~ 9 parts.
Described a kind of Chinese medicinal ointment for the treatment of mosquito bite, preferably includes the composition of following weight parts:
Semen Phaseoli zymolyte 5 parts,
Spina Gleditsiae ethanol extract 6 parts,
Camphor water extract 4 parts,
Areca powder 7 parts,
8 parts, vaseline,
Starch 7 parts.
Treat a preparation method for the Chinese medicinal ointment of mosquito bite, described preparation method step is as follows:
(1) Semen Phaseoli is smashed to pieces, the deionized water of 6 times of weight is added after smashing to pieces, 1,4 beta-glucanase is added again after adding water, the addition of 1,4 beta-glucanase is the 1wt% of water weight, after adding, temperature is adjusted to 35 DEG C, stir enzymolysis, mixing time is 3h, stirring is rear centrifugal, collects supernatant and carry out vacuum concentration to obtain Semen Phaseoli zymolyte;
(2) pulverized by Spina Gleditsiae, carry out high-temperature stirring extraction after pulverizing with ethanol, Extracting temperature is 55 DEG C, ethanol weight is 4 times of Spina Gleditsiae weight, extraction time is 2h, after extraction under 4000rpm centrifugal 10min, supernatant vacuum concentration is obtained Spina Gleditsiae ethanol extract;
(3) Camphora is carried out vacuum drying, pulverize after vacuum drying, then carry out hot water extraction, hot extraction temperature is 70 DEG C, and water weight is 5 times of Camphora weight, and hot extraction time is 4h, centrifugal after lixiviate, and supernatant vacuum concentration is obtained camphor water extract;
(4) Semen Phaseoli zymolyte 3 ~ 7 parts, Spina Gleditsiae ethanol extract 4 ~ 9 parts, camphor water extract 3 ~ 6 parts, areca powder 4 ~ 8 parts, 6 ~ 12 parts, vaseline, starch 5 ~ 10 parts is got by weight, mix and stir, fill is carried out, for treating the Chinese medicinal ointment of mosquito bite after stirring.
Preferably, describedly a kind ofly treat that Semen Phaseoli zymolyte in the preparation method of the Chinese medicinal ointment of mosquito bite is 4 ~ 6 parts, Spina Gleditsiae ethanol extract is 5 ~ 7 parts, camphor water extract is 4 ~ 5 parts, areca powder is 6 ~ 7 parts, vaseline is 7 ~ 10 parts, starch is 6 ~ 9 parts.
Further preferred, described a kind ofly treat that Semen Phaseoli zymolyte in the preparation method of the Chinese medicinal ointment of mosquito bite is 5 parts, Spina Gleditsiae ethanol extract is 6 parts, camphor water extract is 4 parts, areca powder is 7 parts, vaseline is 8 parts, starch is 7 parts.
Beneficial effect: in the unguentum for the treatment of mosquito bite of the present invention, main component is Semen Phaseoli zymolyte, Spina Gleditsiae ethanol extract, camphor water extract and areca powder, all obtained by natural extract mode, be different from the unguentum of conventional treatment mosquito bite, by extracting and enzymolysis above-mentioned main component, the Chinese medicinal ointment prepared instant effect, curative effect in treatment mosquito bite is also more remarkable.
Detailed description of the invention
Embodiment 1
(1) Semen Phaseoli is smashed to pieces, the deionized water of 6 times of weight is added after smashing to pieces, 1,4 beta-glucanase is added again after adding water, the addition of 1,4 beta-glucanase is the 1wt% of water weight, after adding, temperature is adjusted to 35 DEG C, stir enzymolysis, mixing time is 3h, stirring is rear centrifugal, collects supernatant and carry out vacuum concentration to obtain Semen Phaseoli zymolyte; (2) pulverized by Spina Gleditsiae, carry out high-temperature stirring extraction after pulverizing with ethanol, Extracting temperature is 55 DEG C, ethanol weight is 4 times of Spina Gleditsiae weight, extraction time is 2h, after extraction under 4000rpm centrifugal 10min, supernatant vacuum concentration is obtained Spina Gleditsiae ethanol extract; (3) Camphora is carried out vacuum drying, pulverize after vacuum drying, then carry out hot water extraction, hot extraction temperature is 70 DEG C, and water weight is 5 times of Camphora weight, and hot extraction time is 4h, centrifugal after lixiviate, and supernatant vacuum concentration is obtained camphor water extract; (4) get Semen Phaseoli zymolyte 3g, Spina Gleditsiae ethanol extract 4g, camphor water extract 6g, areca powder 8g, vaseline 12g, starch 10g by weight, mix and stir, after stirring, carrying out fill, for treating the Chinese medicinal ointment of mosquito bite.
Embodiment 2
(1) Semen Phaseoli is smashed to pieces, the deionized water of 6 times of weight is added after smashing to pieces, 1,4 beta-glucanase is added again after adding water, the addition of 1,4 beta-glucanase is the 1wt% of water weight, after adding, temperature is adjusted to 35 DEG C, stir enzymolysis, mixing time is 3h, stirring is rear centrifugal, collects supernatant and carry out vacuum concentration to obtain Semen Phaseoli zymolyte; (2) pulverized by Spina Gleditsiae, carry out high-temperature stirring extraction after pulverizing with ethanol, Extracting temperature is 55 DEG C, ethanol weight is 4 times of Spina Gleditsiae weight, extraction time is 2h, after extraction under 4000rpm centrifugal 10min, supernatant vacuum concentration is obtained Spina Gleditsiae ethanol extract; (3) Camphora is carried out vacuum drying, pulverize after vacuum drying, then carry out hot water extraction, hot extraction temperature is 70 DEG C, and water weight is 5 times of Camphora weight, and hot extraction time is 4h, centrifugal after lixiviate, and supernatant vacuum concentration is obtained camphor water extract; (4) get Semen Phaseoli zymolyte 7g, Spina Gleditsiae ethanol extract 9g, camphor water extract 3g, areca powder 4g, vaseline 6g, starch 5g by weight, mix and stir, after stirring, carrying out fill, for treating the Chinese medicinal ointment of mosquito bite.
Embodiment 3
(1) Semen Phaseoli is smashed to pieces, the deionized water of 6 times of weight is added after smashing to pieces, 1,4 beta-glucanase is added again after adding water, the addition of 1,4 beta-glucanase is the 1wt% of water weight, after adding, temperature is adjusted to 35 DEG C, stir enzymolysis, mixing time is 3h, stirring is rear centrifugal, collects supernatant and carry out vacuum concentration to obtain Semen Phaseoli zymolyte; (2) pulverized by Spina Gleditsiae, carry out high-temperature stirring extraction after pulverizing with ethanol, Extracting temperature is 55 DEG C, ethanol weight is 4 times of Spina Gleditsiae weight, extraction time is 2h, after extraction under 4000rpm centrifugal 10min, supernatant vacuum concentration is obtained Spina Gleditsiae ethanol extract; (3) Camphora is carried out vacuum drying, pulverize after vacuum drying, then carry out hot water extraction, hot extraction temperature is 70 DEG C, and water weight is 5 times of Camphora weight, and hot extraction time is 4h, centrifugal after lixiviate, and supernatant vacuum concentration is obtained camphor water extract; (4) get Semen Phaseoli zymolyte 6g, Spina Gleditsiae ethanol extract 7g, camphor water extract 4g, areca powder 7g, vaseline 7g, starch 9g by weight, mix and stir, after stirring, carrying out fill, for treating the Chinese medicinal ointment of mosquito bite.
Embodiment 4
(1) Semen Phaseoli is smashed to pieces, the deionized water of 6 times of weight is added after smashing to pieces, 1,4 beta-glucanase is added again after adding water, the addition of 1,4 beta-glucanase is the 1wt% of water weight, after adding, temperature is adjusted to 35 DEG C, stir enzymolysis, mixing time is 3h, stirring is rear centrifugal, collects supernatant and carry out vacuum concentration to obtain Semen Phaseoli zymolyte; (2) pulverized by Spina Gleditsiae, carry out high-temperature stirring extraction after pulverizing with ethanol, Extracting temperature is 55 DEG C, ethanol weight is 4 times of Spina Gleditsiae weight, extraction time is 2h, after extraction under 4000rpm centrifugal 10min, supernatant vacuum concentration is obtained Spina Gleditsiae ethanol extract; (3) Camphora is carried out vacuum drying, pulverize after vacuum drying, then carry out hot water extraction, hot extraction temperature is 70 DEG C, and water weight is 5 times of Camphora weight, and hot extraction time is 4h, centrifugal after lixiviate, and supernatant vacuum concentration is obtained camphor water extract; (4) get Semen Phaseoli zymolyte 4g, Spina Gleditsiae ethanol extract 5g, camphor water extract 5g, areca powder 6g, vaseline 10g, starch 6g by weight, mix and stir, after stirring, carrying out fill, for treating the Chinese medicinal ointment of mosquito bite.
Embodiment 5
(1) Semen Phaseoli is smashed to pieces, the deionized water of 6 times of weight is added after smashing to pieces, 1,4 beta-glucanase is added again after adding water, the addition of 1,4 beta-glucanase is the 1wt% of water weight, after adding, temperature is adjusted to 35 DEG C, stir enzymolysis, mixing time is 3h, stirring is rear centrifugal, collects supernatant and carry out vacuum concentration to obtain Semen Phaseoli zymolyte; (2) pulverized by Spina Gleditsiae, carry out high-temperature stirring extraction after pulverizing with ethanol, Extracting temperature is 55 DEG C, ethanol weight is 4 times of Spina Gleditsiae weight, extraction time is 2h, after extraction under 4000rpm centrifugal 10min, supernatant vacuum concentration is obtained Spina Gleditsiae ethanol extract; (3) Camphora is carried out vacuum drying, pulverize after vacuum drying, then carry out hot water extraction, hot extraction temperature is 70 DEG C, and water weight is 5 times of Camphora weight, and hot extraction time is 4h, centrifugal after lixiviate, and supernatant vacuum concentration is obtained camphor water extract; (4) get Semen Phaseoli zymolyte 5g, Spina Gleditsiae ethanol extract 6g, camphor water extract 4g, areca powder 7g, vaseline 8g, starch 7g by weight, mix and stir, after stirring, carrying out fill, for treating the Chinese medicinal ointment of mosquito bite.
By by the painting Chinese medicinal ointment of embodiment 1 to 5 respectively of the patient after mosquito bite, observe its detumescence situation, antipruritic situation.
10 patients are after the Chinese medicinal ointment of embodiment 1 has been used in painting, and 5 patients symptomatic obtain significant alleviation, and 5 patients obtain and cure completely.
10 patients are after the Chinese medicinal ointment of embodiment 2 has been used in painting, and 6 patients symptomatic obtain significant alleviation, and 4 patients obtain and cure completely.
10 patients are after the Chinese medicinal ointment of embodiment 3 has been used in painting, and 3 patients symptomatic obtain significant alleviation, and 7 patients obtain and cure completely, and responding time is very fast.
10 patients are after the Chinese medicinal ointment of embodiment 4 has been used in painting, and 2 patients symptomatic obtain significant alleviation, and 8 patients obtain and cure completely, and responding time is very fast.
10 patients are after the Chinese medicinal ointment of embodiment 5 has been used in painting, and 10 patients obtain and cure completely, and responding time quickly.
Claims (6)
1. treat a Chinese medicinal ointment for mosquito bite, it is characterized in that the Chinese medicinal ointment of described treatment mosquito bite comprises the composition of following weight parts:
Semen Phaseoli zymolyte 3 ~ 7 parts,
Spina Gleditsiae ethanol extract 4 ~ 9 parts,
Camphor water extract 3 ~ 6 parts,
Areca powder 4 ~ 8 parts,
6 ~ 12 parts, vaseline,
Starch 5 ~ 10 parts.
2. a kind of Chinese medicinal ointment for the treatment of mosquito bite according to claim 1, is characterized in that the Chinese medicinal ointment of described treatment mosquito bite comprises the composition of following weight parts:
Semen Phaseoli zymolyte 4 ~ 6 parts,
Spina Gleditsiae ethanol extract 5 ~ 7 parts,
Camphor water extract 4 ~ 5 parts,
Areca powder 6 ~ 7 parts,
7 ~ 10 parts, vaseline,
Starch 6 ~ 9 parts.
3. a kind of Chinese medicinal ointment for the treatment of mosquito bite according to claim 1, is characterized in that the Chinese medicinal ointment of described treatment mosquito bite comprises the composition of following weight parts:
Semen Phaseoli zymolyte 5 parts,
Spina Gleditsiae ethanol extract 6 parts,
Camphor water extract 4 parts,
Areca powder 7 parts,
8 parts, vaseline,
Starch 7 parts.
4. treat a preparation method for the Chinese medicinal ointment of mosquito bite, it is characterized in that described preparation method step is as follows:
(1) Semen Phaseoli is smashed to pieces, the deionized water of 6 times of weight is added after smashing to pieces, 1,4 beta-glucanase is added again after adding water, the addition of 1,4 beta-glucanase is the 1wt% of water weight, after adding, temperature is adjusted to 35 DEG C, stir enzymolysis, mixing time is 3h, stirring is rear centrifugal, collects supernatant and carry out vacuum concentration to obtain Semen Phaseoli zymolyte;
(2) pulverized by Spina Gleditsiae, carry out high-temperature stirring extraction after pulverizing with ethanol, Extracting temperature is 55 DEG C, ethanol weight is 4 times of Spina Gleditsiae weight, extraction time is 2h, after extraction under 4000rpm centrifugal 10min, supernatant vacuum concentration is obtained Spina Gleditsiae ethanol extract;
(3) Camphora is carried out vacuum drying, pulverize after vacuum drying, then carry out hot water extraction, hot extraction temperature is 70 DEG C, and water weight is 5 times of Camphora weight, and hot extraction time is 4h, centrifugal after lixiviate, and supernatant vacuum concentration is obtained camphor water extract;
(4) Semen Phaseoli zymolyte 3 ~ 7 parts, Spina Gleditsiae ethanol extract 4 ~ 9 parts, camphor water extract 3 ~ 6 parts, areca powder 4 ~ 8 parts, 6 ~ 12 parts, vaseline, starch 5 ~ 10 parts is got by weight, mix and stir, fill is carried out, for treating the Chinese medicinal ointment of mosquito bite after stirring.
5. a kind of preparation method for the treatment of the Chinese medicinal ointment of mosquito bite according to claim 4, is characterized in that in described preparation method, Semen Phaseoli zymolyte is 4 ~ 6 parts, Spina Gleditsiae ethanol extract is 5 ~ 7 parts, camphor water extract is 4 ~ 5 parts, areca powder is 6 ~ 7 parts, vaseline is 7 ~ 10 parts, starch is 6 ~ 9 parts.
6. a kind of preparation method for the treatment of the Chinese medicinal ointment of mosquito bite according to claim 4, is characterized in that in described preparation method, Semen Phaseoli zymolyte is 5 parts, Spina Gleditsiae ethanol extract is 6 parts, camphor water extract is 4 parts, areca powder is 7 parts, vaseline is 8 parts, starch is 7 parts.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111588672A (en) * | 2020-06-30 | 2020-08-28 | 河北农业大学 | Edible itching-relieving emulsion for mosquito bites and preparation method thereof |
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| CN102048817A (en) * | 2010-12-21 | 2011-05-11 | 东莞市腾业实业有限公司 | Itch relieving and detoxifying liquid for mosquito and insect biting |
| CN102784350A (en) * | 2012-08-07 | 2012-11-21 | 孙雅儒 | Mite killing bactericide and preparation method of mite killing bactericide |
| CN104337962A (en) * | 2013-08-06 | 2015-02-11 | 洪艳平 | External medicinal liquor for treating erythra |
-
2014
- 2014-10-21 CN CN201410560670.9A patent/CN104324178A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1559621A (en) * | 2004-03-03 | 2005-01-05 | 张玉珍 | Medical wet cotton for itch and pain stopping |
| CN102048817A (en) * | 2010-12-21 | 2011-05-11 | 东莞市腾业实业有限公司 | Itch relieving and detoxifying liquid for mosquito and insect biting |
| CN102784350A (en) * | 2012-08-07 | 2012-11-21 | 孙雅儒 | Mite killing bactericide and preparation method of mite killing bactericide |
| CN104337962A (en) * | 2013-08-06 | 2015-02-11 | 洪艳平 | External medicinal liquor for treating erythra |
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| Title |
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| CN111588672A (en) * | 2020-06-30 | 2020-08-28 | 河北农业大学 | Edible itching-relieving emulsion for mosquito bites and preparation method thereof |
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Application publication date: 20150204 |