CN104307001A - Ultrasonoscopy-diagnosis traditional Chinese medicine-assisted imaging preparation and preparation method thereof - Google Patents

Abstract

The invention provides an ultrasonoscopy-diagnosis traditional Chinese medicine-assisted imaging preparation and a preparation method thereof. The traditional Chinese medicine-assisted imaging preparation comprises the following crude drugs: concha margaritiferallsta, acropora pulchra(brook), oroxylum indicum, cushaw stems, phellinus igniarius, hyacinth dolichos spermoderm, morinda parvifolia, carageen, Chinese desmos leaves, herba belladonnae, spike aletris herb, stachys baicalensis, herba chelidonii, limonium sinense, rhodomyrtus tomentosa, radix kadsurae coccineae and tephrosia root. The invention has the benefits that the ultrasonoscopy-diagnosis traditional Chinese medicine-assisted imaging preparation is safe in use and convenient to use, provides a powerful basis for clinic diagnosis, and is an more ideal assisted imaging preparation, no pains, toxicity or an anaphylactic reaction can be caused, the check time is short, and the imaging rate is high.

Description

Video picture preparation and preparation method thereof assisted by a kind of ultrasonic image diagnosis Chinese medicine

Technical field

The present invention relates to engineering of traditional Chinese medicine technical field, particularly relate to a kind of ultrasonic image diagnosis Chinese medicine for B ultrasonic and assist video picture preparation and preparation method thereof.

Background technology

Ultrasonic image diagnosis is one of important diagnostic method in medical science.Ultrasound wave has three to act on greatly to material: one is mechanism, because ultrasonic energy is huge, often makes material particle do altofrequency mechanical vibration, thus produce smash, condense, agitation effects.Two is warm-heat effect, and ul-trasonic irradiation is when material, and its energy is absorbed by material, thus makes mass temperature raise phenomenon.Three is cavitations, when ul-trasonic irradiation is on liquid, become sparse in the region (if any microscopic bubble etc.) of liquid internal stress weakness due to acoustic pressure great variety, at this moment around under the effect of fluid molecule pulling force, form a little cavity, be cavitation.This cavity time of staying is not long, collapses again under huge acoustic pressure effect, and formed due to cavity and disappear, producing a large amount of bubble will affect ultrasonic diagnosis effect, so, eliminate the Main Function that bubble is ultrasonic contrast agent.

At present, for B ultrasonic gastrointestinal contrast agent, prior art describes the contrast agent be mixed with by the 100 order fine powders of Endoconcha Sepiae fine powder 80% and the Pseudobulbus Bletillae (Rhizoma Bletillae) 20%, to gastrointestinal disease, there is convergence, antacid effect, but weak point is patient take contrast agent after to produce strong echo luminous point not enough, reflecting effect is not good, and the display of coat of the stomach level is unintelligible; After patient takes this contrast agent, gastric acid strong reaction, has pain and sense of discomfort, is unfavorable for the ultrasonic contrast of gastrointestinal, can not applies this contrast agent to gastrorrhagia patient.

Another kind of fast ultrasonic image-developing liquor preparation method is that make imaging liquid, excellent video picture rate reaches 87% through decocting, distilling, concentrate after bitter bucket, MIXIANG, abdomen floss, Pericarpium Citri Reticulatae Viride, Radix Glycyrrhizae, sucrose being mixed in proportion.Used bitter bucket in this prescription, taste is extremely bitter, thus improves mouthfeel with sucrose, and sucrose enters in gastric juice and easily produces bubble, thus has impact to imaging results, and in addition, this invention product is without therapeutical effect.

Summary of the invention

Technical problem to be solved by this invention is, utilizes the theory of Chinese medical science that China is traditional, in ultrasound diagnosis process, a kind of use safety, avirulence are provided, have no side effect, review time is short, and video picture rate is high, and video picture preparation and preparation method thereof assisted by ultrasonic image diagnosis Chinese medicine easy to use.

In order to solve the problems of the technologies described above; the invention provides a kind of ultrasonic image diagnosis Chinese medicine and assist video picture preparation; wherein, described Chinese medicine assists video picture preparation to comprise following raw medicinal material: Concha Margaritifera, Qing Lang ?, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris, Herba Morindae Parvifoliae, chondrus ocellatus Holmes, Folium desmoris, Herba Belladonnae, Herba Aletridis spicatae, Herba Stachydis, Herba Chelidonii, Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae.

Described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be: Concha Margaritifera 20 ~ 30 parts, Qing Lang ?20 ~ 30 parts, Semen Oroxyli 10 ~ 20 parts, Caulis Cucurbitae 15 ~ 25 parts, Phellinus igniarius (L. ex Fr.) Quel. 10 ~ 20 parts, Testa dolichoris 10 ~ 20 parts, Herba Morindae Parvifoliae 15 ~ 25 parts, chondrus ocellatus Holmes 5 ~ 15 parts, Folium desmoris 5 ~ 15 parts, Herba Belladonnae 5 ~ 15 parts, Herba Aletridis spicatae 10 ~ 20 parts, Herba Stachydis 10 ~ 20 parts, Herba Chelidonii 5 ~ 15 parts, Herba Limonii Gmelinii 30 ~ 40 parts, Fructus Rhodomyrti 15 ~ 25 parts, Caulis Kadsurae Coccineae 30 ~ 40 parts and Radix Tephrosiae purpureae 5 ~ 15 parts.

Described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be preferably: Concha Margaritifera 20 ~ 25 parts, Qing Lang ?20 ~ 25 parts, Semen Oroxyli 10 ~ 15 parts, Caulis Cucurbitae 15 ~ 20 parts, Phellinus igniarius (L. ex Fr.) Quel. 10 ~ 15 parts, Testa dolichoris 10 ~ 15 parts, Herba Morindae Parvifoliae 15 ~ 20 parts, chondrus ocellatus Holmes 5 ~ 10 parts, Folium desmoris 5 ~ 10 parts, Herba Belladonnae 5 ~ 10 parts, Herba Aletridis spicatae 10 ~ 15 parts, Herba Stachydis 10 ~ 15 parts, Herba Chelidonii 5 ~ 10 parts, Herba Limonii Gmelinii 30 ~ 35 parts, Fructus Rhodomyrti 15 ~ 20 parts, Caulis Kadsurae Coccineae 30 ~ 35 parts and Radix Tephrosiae purpureae 5 ~ 10 parts.

Described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be preferably: Concha Margaritifera 22 parts, Qing Lang ?24 parts, Semen Oroxyli 13 parts, Caulis Cucurbitae 18 parts, Phellinus igniarius (L. ex Fr.) Quel. 11 parts, Testa dolichoris 14 parts, Herba Morindae Parvifoliae 16 parts, chondrus ocellatus Holmes 7 parts, Folium desmoris 8 parts, Herba Belladonnae 6 parts, Herba Aletridis spicatae 12 parts, Herba Stachydis 14 parts, Herba Chelidonii 6 parts, Herba Limonii Gmelinii 34 parts, Fructus Rhodomyrti 17 parts, Caulis Kadsurae Coccineae 31 parts and Radix Tephrosiae purpureae 8 parts.

Described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be preferably: Concha Margaritifera 24 parts, Qing Lang ?21 parts, Semen Oroxyli 11 parts, Caulis Cucurbitae 16 parts, Phellinus igniarius (L. ex Fr.) Quel. 14 parts, Testa dolichoris 11 parts, Herba Morindae Parvifoliae 18 parts, chondrus ocellatus Holmes 6 parts, Folium desmoris 7 parts, Herba Belladonnae 7 parts, Herba Aletridis spicatae 14 parts, Herba Stachydis 12 parts, Herba Chelidonii 8 parts, Herba Limonii Gmelinii 32 parts, Fructus Rhodomyrti 19 parts, Caulis Kadsurae Coccineae 34 parts and Radix Tephrosiae purpureae 6 parts.

In order to solve the problems of the technologies described above, the invention provides the preparation method that video picture preparation assisted by a kind of above-mentioned ultrasonic image diagnosis Chinese medicine, described Chinese medicine assists the dosage form of video picture preparation to be powder, and it comprises the following steps:

The first step, by Concha Margaritifera, Qing Lang ?, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris and Herba Morindae Parvifoliae mix in described ratio, with being the dissolve with ethanol of 85% ~ 95% relative to the determining alcohol of 3 ~ 5 times of mixture quality obtained, reflux was extracted after 2 ~ 4 hours, filter, obtain the first filtrate; By filtering residue again with the dissolve with ethanol of the determining alcohol 85% ~ 95% of 1 ~ 2 times relative to the mixture quality obtained, reflux was extracted after 1 ~ 2 hour, filtered, obtained the second filtrate; Merge the first filtrate and the second filtrate, decompression recycling ethanol to be concentrated into liquor strength be 0.7 ~ 0.9g crude drug/mL, through the macroporous adsorptive resins eluting that volume is 5L, first use deionized water or the distilled water eluting of 5 times of resin column volumes, be 90% ~ 95% ethanol elution with the determining alcohol of 3 times of resin column volumes again, collect ethanol elution, concentrating under reduced pressure removing ethanol, drying is also ground into powder;

Second step, Herba Chelidonii, Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae are mixed in described ratio, add the ethanol of the determining alcohol 85% ~ 95% of 2 ~ 4 times relative to the mixture quality obtained, heating and refluxing extraction 1 ~ 2 time, extracting solution merges, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the mastic of 1.20 ~ 1.23, and the mastic spray dryer after concentrated is dried to powder;

3rd step, mixes surplus stock medical material in described ratio, adds the water dissolution of 4 ~ 6 times relative to the mixture quality obtained, and heating decoction 2 ~ 4 hours, filters; By filtering residue again with the water dissolution of 2 ~ 4 times relative to the mixture quality obtained, again heat decoction 1 ~ 2 hour, filter; Merge the filtrate of twice, concentrating under reduced pressure removing moisture, drying is also ground into powder;

4th step, the powder mixing first step, second step and the 3rd step obtained, is screened into 100 ~ 200 object fine powders subsequently, is dropped in mixing and blending machine by the fine powder of acquisition and stirs, namely obtain described Chinese powder medicine.

In order to solve the problems of the technologies described above, the invention provides the preparation method that video picture preparation assisted by a kind of above-mentioned ultrasonic image diagnosis Chinese medicine, when prepared dosage form is oral liquid, comprising the following steps:

The first step, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris, Herba Morindae Parvifoliae, chondrus ocellatus Holmes, Folium desmoris, Herba Belladonnae, Herba Aletridis spicatae, Herba Stachydis and Herba Chelidonii are mixed in proportion rear pulverizing, be that the methanol of 75% ~ 85% is as solvent with determining alcohol, flood 20 ~ 50 hours, adopt percolation with the speed of 1 ~ 3ml per minute slowly percolation, collect percolate, concentrating under reduced pressure is also dry, obtain and get dry extract, be ground into powder, the quality of the methanol added is 3 ~ 5 times of first step mixture quality;

Second step, get the distilled water being equivalent to surplus stock medicinal material mixture quality 4 ~ 8 times, first by Concha Margaritifera and Qing Lang ?pulverize after, add in distilled water, decoct 1 ~ 2 hour, and then continue decoction 2 ~ 3 hours by adding in decoction liquor after the pulverizing of Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae, filter, obtain the first filtrate; Filtering residue is added the distilled water relative to its quality 2 ~ 4 times, decoct 1 ~ 3 hour, filter, obtain the second filtrate; Merge the first filtrate and the second filtrate, the water of concentrated removal 2/3 ~ 3/4 volume, adds the ethanol that determining alcohol is 85 ~ 95%, makes determining alcohol reach 70% ~ 80%, leaves standstill 12 ~ 24 hours, filters, concentrating under reduced pressure, dry, obtains and gets dry extract, be ground into powder;

3rd step, the powder mixing first step and second step obtained, add the distilled water relative to powder quality 3 ~ 5 times amount, the sucrose of 0.1 ~ 0.5 times, the sodium benzoate of 0.005 ~ 0.05 times, stir, boil, cooling, filter, subpackage, namely sterilizing obtains oral liquid.

Beneficial effect of the present invention: use safety, no pain, avirulence, without anaphylaxis, the review time is short, video picture rate is high, easy to use, for clinical diagnosis provides strong foundation, is ideal auxiliary development preparation.

Detailed description of the invention

The invention provides a kind of ultrasonic image diagnosis Chinese medicine and assist video picture preparation, described Chinese medicine assists video picture preparation to comprise following raw medicinal material: Concha Margaritifera, Qing Lang ?, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris, Herba Morindae Parvifoliae, chondrus ocellatus Holmes, Folium desmoris, Herba Belladonnae, Herba Aletridis spicatae, Herba Stachydis, Herba Chelidonii, Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae.

The pharmacology of various raw medicinal material is as follows:

Concha Margaritifera: salty, cold.Return liver, heart channel.Suppressing the hyperactive liver and subsiding YANG, arresting convulsion hemostasis, controls dizziness, tinnitus, cardiopalmus, and insomnia is demented, spits blood, epistaxis, metrorrhagia.

Qing Lang ?: acrid in the mouth, property put down.Dispelling wind for relieving itching, removing toxic substances clots absorbing.Main skin pruritus, bald in vain, carbuncle and ulcer, stops in postnatal blood stasis, stranguria caused by urinary stone.

Semen Oroxyli: bitter, cold.Return lung, spleen, stomach, Liver Channel.Lung moistening, soothing the liver, stomach function regulating, granulation promoting.Control cough, sore throat, hoarseness, stomachache due to hyperactive liver-QI attacking the stomach, the open sore part is not held back.

Caulis Cucurbitae: sweet in the mouth, bitter, cold nature.Return liver, stomach, lung meridian.Lung heat clearing, suppressing the hyperactive liver, stomach function regulating, dredging collateral.Main pulmonary tuberculosis low grade fever, stomachache due to hyperactive liver-QI attacking the stomach, menoxenia, acute catarrhal conjunctivitis swelling pain, burn due to hot liquid or fire.

Phellinus igniarius (L. ex Fr.) Quel.: micro-hardship, cold.Profit the five internal organs, softening the hard mass, toxin expelling, hemostasis, invigorates blood circulation, stomach function regulating antidiarrheal.Control gonorrhea, bleeding not during menses, lump in the abdomen, hypochondrium fluid retention, diarrhea due to hypofunction of the spleen.

Testa dolichoris: sweet, bitter, temperature.Return spleen, large intestine channel.To relieve summer heat removing dampness, invigorating the spleen and regulating the stomach.Accumulate in main heat-damp in summer, vomiting is had loose bowels, uncomfortable in chest indigestion and loss of appetite, beriberi edema, women's leukorrhagia.

Herba Morindae Parvifoliae: sweet is cool.Return lung meridian.Heat-clearing and toxic substances removing, eliminating stasis to stop pain, stomach function regulating removing dampness.Main cold cough, pertussis, dyspepsia, eczema, traumatic injury, lumbar muscle strain.

Chondrus ocellatus Holmes: sweet is salty, cold.Return large intestine, stomach warp.Heat-clearing and toxic substances removing, stomach function regulating relieving constipation.Main laryngopharynx swelling and pain, traumatic injury, flu cold and heat, mumps, gastralgia, dryness of the intestine constipation.

Folium desmoris: pungent, bitter, temperature.Return spleen, Liver Channel.Expelling wind and removing dampness, blood-activating analgetic, invigorating the spleen and regulating the stomach, preventing the attack (or recurrence) of malaria parasite killing.Main rheumatic ostalgia, malaria, edema, traumatic injury, rubella, scabies, rotten foot.

Herba Belladonnae: relieving spasm to stop pain, secretion inhibitor.Main gastric and duodenal ulcers, gastrointestinal tract, kidney, biliary colic, vomiting and nausea, night sweat, sialorrhea.

Herba Aletridis spicatae: bitter, sweet is flat.Lung heat clearing, reduces phlegm, and cough-relieving is invigorated blood circulation, parasite killing.Control cough to spit blood, pertussis, asthma, lung abscess, consolidate carbuncle, discharging fresh blood stool, married woman's breast is few, amenorrhea, infantile malnutrition, ascarid." Shaanxi Chinese herbal medicine ": clearing away heat-damp and promoting diuresis, lung moistening, promoting blood flow to regulate menstruation.Control dyspepsia, hepatitis, hyperchlorhydria, pulmonary tuberculosis, cough, hypogalactia, leucorrhea, amenorrhea lumbago.

Herba Stachydis: sweet, pungent, tepor.To dispel the wind removing toxic substances, hemostasis.For flu, laryngopharynx swelling and pain, spits blood, epistaxis, metrorrhagia, hyperchlorhydria; Furuncle toxic swelling is controlled in external.

Herba Chelidonii: bitter, cool.Return lung, the heart, kidney channel.Town is sick, cough-relieving, diuresis, removing toxic substances.Main stomachache, stomachache, enteritis, dysentery, chronic bronchitis, pertussis, cough, jaundice, edema, ascites, scabies skin ulcer swells, snake bite and insect sting." the conventional Chinese herbal medicine in the north ": have analgesia, cough-relieving, sterilization, diuresis, separate the merit of sore.Treating acute and chronic gastritis, gastric ulcer, stomachache, dysentery, cough, cirrhotic ascites.

Herba Limonii Gmelinii: bitter, salty, temperature.Invigorate blood circulation, hemostasis, warming middle-JIAO and strengthening the spleen, strengthening by means of tonics.For menoxenia, dysfunctional uterine hemorrhage, bleeding hemorrhoids, gastric ulcer, insufficiency of the spleen edema.

Fructus Rhodomyrti: sweet in the mouth, puckery, property is put down.Return liver, spleen channel.Nourishing blood and hemoslasis, astringing intestine to stop diarrhea controlling nocturnal emission with astringent drugs.Main blood deficiency is weak, spits blood, epistaxis, and impairment caused by overstrain hemoptysis, has blood in stool, metrorrhagia, seminal emission, leukorrhagia, dysentery, and proctoptosis is scalded, traumatic hemorrhage.

Caulis Kadsurae Coccineae: pungent, micro-hardship, warm in nature.Promoting the circulation of QI to relieve pain, dissipating blood stasis dredging collateral.Gastric and duodenal ulcers, chronic gastritis, acute gastroenteritis, rheumatic arthralgia, traumatic injury, fracture, dysmenorrhea, cold, postnatal blood stasis is suffered from abdominal pain, colicky.

Radix Tephrosiae purpureae: bitter in the mouth, cool in nature.Return spleen, stomach warp.Heat clearing awayization is stagnant, promoting the circulation of QI to relieve pain, removing dampness to relieve itching.Main flatulence, dyspepsia, ache induced by gastritis.

Described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be: Concha Margaritifera 20 ~ 30 parts, Qing Lang ?20 ~ 30 parts, Semen Oroxyli 10 ~ 20 parts, Caulis Cucurbitae 15 ~ 25 parts, Phellinus igniarius (L. ex Fr.) Quel. 10 ~ 20 parts, Testa dolichoris 10 ~ 20 parts, Herba Morindae Parvifoliae 15 ~ 25 parts, chondrus ocellatus Holmes 5 ~ 15 parts, Folium desmoris 5 ~ 15 parts, Herba Belladonnae 5 ~ 15 parts, Herba Aletridis spicatae 10 ~ 20 parts, Herba Stachydis 10 ~ 20 parts, Herba Chelidonii 5 ~ 15 parts, Herba Limonii Gmelinii 30 ~ 40 parts, Fructus Rhodomyrti 15 ~ 25 parts, Caulis Kadsurae Coccineae 30 ~ 40 parts and Radix Tephrosiae purpureae 5 ~ 15 parts.

Described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be preferably: Concha Margaritifera 20 ~ 25 parts, Qing Lang ?20 ~ 25 parts, Semen Oroxyli 10 ~ 15 parts, Caulis Cucurbitae 15 ~ 20 parts, Phellinus igniarius (L. ex Fr.) Quel. 10 ~ 15 parts, Testa dolichoris 10 ~ 15 parts, Herba Morindae Parvifoliae 15 ~ 20 parts, chondrus ocellatus Holmes 5 ~ 10 parts, Folium desmoris 5 ~ 10 parts, Herba Belladonnae 5 ~ 10 parts, Herba Aletridis spicatae 10 ~ 15 parts, Herba Stachydis 10 ~ 15 parts, Herba Chelidonii 5 ~ 10 parts, Herba Limonii Gmelinii 30 ~ 35 parts, Fructus Rhodomyrti 15 ~ 20 parts, Caulis Kadsurae Coccineae 30 ~ 35 parts and Radix Tephrosiae purpureae 5 ~ 10 parts.

Described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be preferably: Concha Margaritifera 22 parts, Qing Lang ?24 parts, Semen Oroxyli 13 parts, Caulis Cucurbitae 18 parts, Phellinus igniarius (L. ex Fr.) Quel. 11 parts, Testa dolichoris 14 parts, Herba Morindae Parvifoliae 16 parts, chondrus ocellatus Holmes 7 parts, Folium desmoris 8 parts, Herba Belladonnae 6 parts, Herba Aletridis spicatae 12 parts, Herba Stachydis 14 parts, Herba Chelidonii 6 parts, Herba Limonii Gmelinii 34 parts, Fructus Rhodomyrti 17 parts, Caulis Kadsurae Coccineae 31 parts and Radix Tephrosiae purpureae 8 parts.

Described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be preferably: Concha Margaritifera 24 parts, Qing Lang ?21 parts, Semen Oroxyli 11 parts, Caulis Cucurbitae 16 parts, Phellinus igniarius (L. ex Fr.) Quel. 14 parts, Testa dolichoris 11 parts, Herba Morindae Parvifoliae 18 parts, chondrus ocellatus Holmes 6 parts, Folium desmoris 7 parts, Herba Belladonnae 7 parts, Herba Aletridis spicatae 14 parts, Herba Stachydis 12 parts, Herba Chelidonii 8 parts, Herba Limonii Gmelinii 32 parts, Fructus Rhodomyrti 19 parts, Caulis Kadsurae Coccineae 34 parts and Radix Tephrosiae purpureae 6 parts.

In order to solve the problems of the technologies described above, the invention provides the preparation method that video picture preparation assisted by a kind of above-mentioned ultrasonic image diagnosis Chinese medicine, described Chinese medicine assists the dosage form of video picture preparation to be powder, and it comprises the following steps:

The first step, by Concha Margaritifera, Qing Lang ?, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris and Herba Morindae Parvifoliae mix in described ratio, with being the dissolve with ethanol of 85% ~ 95% relative to the determining alcohol of 3 ~ 5 times of mixture quality obtained, reflux was extracted after 2 ~ 4 hours, filter, obtain the first filtrate; By filtering residue again with the dissolve with ethanol of the determining alcohol 85% ~ 95% of 1 ~ 2 times relative to the mixture quality obtained, reflux was extracted after 1 ~ 2 hour, filtered, obtained the second filtrate; Merge the first filtrate and the second filtrate, decompression recycling ethanol to be concentrated into liquor strength be 0.7 ~ 0.9g crude drug/mL, through the macroporous adsorptive resins eluting that volume is 5L, first use deionized water or the distilled water eluting of 5 times of resin column volumes, be 90% ~ 95% ethanol elution with the determining alcohol of 3 times of resin column volumes again, collect ethanol elution, concentrating under reduced pressure removing ethanol, drying is also ground into powder;

Second step, Herba Chelidonii, Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae are mixed in described ratio, add the ethanol of the determining alcohol 85% ~ 95% of 2 ~ 4 times relative to the mixture quality obtained, heating and refluxing extraction 1 ~ 2 time, extracting solution merges, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the mastic of 1.20 ~ 1.23, and the mastic spray dryer after concentrated is dried to powder;

3rd step, mixes surplus stock medical material in described ratio, adds the water dissolution of 4 ~ 6 times relative to the mixture quality obtained, and heating decoction 2 ~ 4 hours, filters; By filtering residue again with the water dissolution of 2 ~ 4 times relative to the mixture quality obtained, again heat decoction 1 ~ 2 hour, filter; Merge the filtrate of twice, concentrating under reduced pressure removing moisture, drying is also ground into powder;

4th step, the powder mixing first step, second step and the 3rd step obtained, is screened into 100 ~ 200 object fine powders subsequently, is dropped in mixing and blending machine by the fine powder of acquisition and stirs, namely obtain described Chinese powder medicine.

In order to solve the problems of the technologies described above, the invention provides the preparation method that video picture preparation assisted by a kind of above-mentioned ultrasonic image diagnosis Chinese medicine, when prepared dosage form is oral liquid, comprising the following steps:

The first step, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris, Herba Morindae Parvifoliae, chondrus ocellatus Holmes, Folium desmoris, Herba Belladonnae, Herba Aletridis spicatae, Herba Stachydis and Herba Chelidonii are mixed in proportion rear pulverizing, be that the methanol of 75% ~ 85% is as solvent with determining alcohol, flood 20 ~ 50 hours, adopt percolation with the speed of 1 ~ 3ml per minute slowly percolation, collect percolate, concentrating under reduced pressure is also dry, obtain and get dry extract, be ground into powder, the quality of the methanol added is 3 ~ 5 times of first step mixture quality;

Second step, get the distilled water being equivalent to surplus stock medicinal material mixture quality 4 ~ 8 times, first by Concha Margaritifera and Qing Lang ?pulverize after, add in distilled water, decoct 1 ~ 2 hour, and then continue decoction 2 ~ 3 hours by adding in decoction liquor after the pulverizing of Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae, filter, obtain the first filtrate; Filtering residue is added the distilled water relative to its quality 2 ~ 4 times, decoct 1 ~ 3 hour, filter, obtain the second filtrate; Merge the first filtrate and the second filtrate, the water of concentrated removal 2/3 ~ 3/4 volume, adds the ethanol that determining alcohol is 85 ~ 95%, makes determining alcohol reach 70% ~ 80%, leaves standstill 12 ~ 24 hours, filters, concentrating under reduced pressure, dry, obtains and gets dry extract, be ground into powder;

3rd step, the powder mixing first step and second step obtained, add the distilled water relative to powder quality 3 ~ 5 times amount, the sucrose of 0.1 ~ 0.5 times, the sodium benzoate of 0.005 ~ 0.05 times, stir, boil, cooling, filter, subpackage, namely sterilizing obtains oral liquid.

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.

Embodiment 1: powder

Get Concha Margaritifera 220g, Qing Lang ?240g, Semen Oroxyli 130g, Caulis Cucurbitae 180g, Phellinus igniarius (L. ex Fr.) Quel. 110g, Testa dolichoris 140g, Herba Morindae Parvifoliae 160g, chondrus ocellatus Holmes 70g, Folium desmoris 80g, Herba Belladonnae 60g, Herba Aletridis spicatae 120g, Herba Stachydis 140g, Herba Chelidonii 60g, Herba Limonii Gmelinii 340g, Fructus Rhodomyrti 170g, Caulis Kadsurae Coccineae 310g and Radix Tephrosiae purpureae 80g.

Its preparation method comprises the following steps:

The first step, by Concha Margaritifera, Qing Lang ?, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris and Herba Morindae Parvifoliae mix in described ratio, be the dissolve with ethanol of 90% with the determining alcohol of 5 times relative to the mixture quality obtained, reflux was extracted after 3 hours, filter, obtain the first filtrate; By filtering residue again with the dissolve with ethanol of the determining alcohol 95% of 2 times relative to the mixture quality obtained, reflux was extracted after 1 hour, filtered, obtained the second filtrate; Merge the first filtrate and the second filtrate, decompression recycling ethanol to be concentrated into liquor strength be 0.9g crude drug/mL, through the macroporous adsorptive resins eluting that volume is 5L, first use deionized water or the distilled water eluting of 5 times of resin column volumes, be 95% ethanol elution with the determining alcohol of 3 times of resin column volumes again, collect ethanol elution, concentrating under reduced pressure removing ethanol, drying is also ground into powder;

Second step, Herba Chelidonii, Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae are mixed in described ratio, add the ethanol of the determining alcohol 95% of 3 times relative to the mixture quality obtained, heating and refluxing extraction 2 times, extracting solution merges, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C 60 DEG C, relative density is the mastic of 1.22, and the mastic spray dryer after concentrated is dried to powder;

3rd step, mixes surplus stock medical material in described ratio, adds the water dissolution of 5 times relative to the mixture quality obtained, and heating decoction 3 hours, filters; By filtering residue again with the water dissolution of 3 times relative to the mixture quality obtained, again heat decoction 2 hours, filter; Merge the filtrate of twice, concentrating under reduced pressure removing moisture, drying is also ground into powder;

4th step, the powder mixing first step, second step and the 3rd step obtained, is screened into 200 object fine powders subsequently, is dropped in mixing and blending machine by the fine powder of acquisition and stirs, namely obtain described Chinese powder medicine.

Embodiment 2: oral liquid

Get Concha Margaritifera 240g, Qing Lang ?210g, Semen Oroxyli 110g, Caulis Cucurbitae 160g, Phellinus igniarius (L. ex Fr.) Quel. 140g, Testa dolichoris 110g, Herba Morindae Parvifoliae 180g, chondrus ocellatus Holmes 60g, Folium desmoris 70g, Herba Belladonnae 70g, Herba Aletridis spicatae 140g, Herba Stachydis 120g, Herba Chelidonii 80g, Herba Limonii Gmelinii 320g, Fructus Rhodomyrti 190g, Caulis Kadsurae Coccineae 340g and Radix Tephrosiae purpureae 60g.

Its preparation method comprises the following steps:

The first step, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris, Herba Morindae Parvifoliae, chondrus ocellatus Holmes, Folium desmoris, Herba Belladonnae, Herba Aletridis spicatae, Herba Stachydis and Herba Chelidonii are mixed in proportion rear pulverizing, be that the methanol of 75% is as solvent with determining alcohol, flood 40 hours, adopt percolation with the speed of 1ml per minute slowly percolation, collect percolate, concentrating under reduced pressure is also dry, obtain and get dry extract, be ground into powder, the quality of the methanol added is 3 times of first step mixture quality;

Second step, get the distilled water being equivalent to surplus stock medicinal material mixture quality 4 times, first by Concha Margaritifera and Qing Lang ?pulverize after, add in distilled water, decoct 1 hour, and then continue decoction 2 hours by adding in decoction liquor after the pulverizing of Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae, filter, obtain the first filtrate; Filtering residue is added the distilled water relative to its quality 2 times, decoct 1 hour, filter, obtain the second filtrate; Merge the first filtrate and the second filtrate, the water of concentrated removal 3/4 volume, adds the ethanol that determining alcohol is 85%, makes determining alcohol reach 70%, leaves standstill 12 hours, filters, concentrating under reduced pressure, dry, obtains and gets dry extract, be ground into powder;

3rd step, the powder mixing first step and second step obtained, add the distilled water relative to powder quality 5 times amount, the sucrose of 0.3 times, the sodium benzoate of 0.02 times, stir, boil, cooling, filter, subpackage, namely sterilizing obtains oral liquid.

Acute toxicity test: be dissolved in distilled water with powder prepared by the embodiment of the present invention 1, gives 4 groups of white mice feeding dispensings or wiping respectively with 80 of clinical consumption per day times, 120 times, 150 times and 230 times, observes 7; The all white mice of result are strong deposits, and its activity, diet, hair, Excreta are no abnormal, have no toxic reaction.Irritation test is carried out to white mouse oral cavity and damaged skin, there are no irritative response and other untoward reaction.

Long term toxicity test: the powder embodiment of the present invention 1 prepared is dissolved in water by 18.43,33.26 and 65.48g crude drug/kg, continuous uses 16 weeks are distinguished to 3 groups of mices, every day 2 times, and drug withdrawal is after 4 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine of the present invention to 3 groups of test mices all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 16 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.Illustrate that Chinese medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.

Pharmacological experiment illustrates:

Pharmacodynamic experiment:

One, the impact that the powder of video picture preparation moves on small intestine movement of mice assisted by Chinese medicine of the present invention

1 test material

1.1 experimental animals: by medical college biological study room, Shandong ICR mice 100, male and female half and half, body weight 18 ~ 24g.

1.2 trial drugs:

1.2.1 the powder of video picture preparation assisted by Chinese medicine of the present invention.Assisted by Chinese medicine of the present invention the powder distilled water of video picture preparation to be dissolved into 0.514,0.259, the medicinal liquid of 0.122g crude drug/ml is stand-by.

1.2.2 atropine sulfate injection (Xinxiang City, Henan Province Chang Le pharmaceutical factory, H41020226), uses front normal saline dilution to become 0.01mg/ml solution.

1.2.3 active carbon; Arabic gum (making containing 10% Radix Acaciae senegalis, the charcoal end distilled water suspension of 5% active carbon).

1.3 testing equipments: T-500 electronic balance (Changshu Shuan Jie test instrunment factory, numbering: 256), PL203 precision electronic balance.

2 test methods

Select 18 ~ 24g body weight mice, be divided into 5 groups by the method for body weight random stratified, be i.e. blank group, positive drug (atropine) group, the high, medium and low dosage group of Chinese powder medicine of the present invention.Often organize 20, male and female half and half.Blank group and atropine group gavage distilled water 30ml/kg, the other gavage of high, medium and low dosage component Chinese powder medicine medicinal liquid of the present invention 14,7,3.5g crude drug/kg, 1 time/d.Gavage is after 7 days, can't help water 18h in the experiment the previous day of fasting at dusk, and after the 8th day last administration 1h (atropine diluent 0.1mg/kg5min), each group gavage charcoal end suspension 0.2ml/ only.Animal is put to death after 20min; open abdominal cavity and be separated mesentery; see that coat of the stomach clear layer is visible, and this auxiliary video picture preparation takes down, stomach week mucosa is played a protective role; ultrasound display screen can be seen place's video pictures such as gastral cavity size, form, cardia, pylorus, gastric antrum, duodenum, lesser gastric curvature, greater gastric curvature obvious; each position focus is high-visible, and to perigastric organs as liver, gallbladder, pancreas display clear, clip front end is to pylorus; rear end, to the intestinal tube of ileocecus, is placed on pallet.Gently small intestinal is put into straight line, measures Length of intestine as " total small intestinal length ".From pylorus to the distance in prepared Chinese ink forward position as " distance that prepared Chinese ink advances at enteral ".Formulae discovery ink progradation: ink progradation=(prepared Chinese ink is in enteral advance distance/small intestinal total length) × 100%.

3 result of the tests

Compare with matched group, positive drug atropine group charcoal end delaunay triangle rate obviously reduces (P<0.05), and the gastric peristalsis of Chinese powder medicine of the present invention is obviously hyperfunction, compares with model control group, can obviously promote gastrointestinal motility function.In table 1.

Table 1 Chinese medicine of the present invention assists the powder of video picture preparation on the impact of the hyperfunction mouse small intestine motion of intestinal propulsion

Group	Number of cases	Delaunay triangle rate %
			Normal group	20	41.85±3.68
Positive drug atropine group	20	54.55±9.23***
			Powder 3.5g crude drug/kg of the present invention	20	68.34±15.42**
Powder 7g crude drug/kg of the present invention	20	78.34±10.58
			Powder 14g crude drug/kg of the present invention	20	89.58±10.46

Note: compare with Normal group: P<0.05, compares with model control group: * * P<0.01, * * * P<0.001.

Conclusion (of pressure testing): Chinese medicine of the present invention assists the powder 3.5g/kg of video picture preparation to have obvious inhibitory action to the motion of gastrointestinal motility hyperfunctioning mouse small intestine, increases, show the trend promoting bowel movement effect with dosage.This test have studied from body and the impact of in vitro function of intestinal canal, stopping leak, antibacterial, the anti-immunity of antiinflammatory etc. the powder treatment gastropathy that video picture preparation assisted by Chinese medicine of the present invention, the Pharmacological Mechanism of enteritis, dysentery, gastrointestinal motility can be promoted, digestion, absorption, and have certain bacteriostasis, and show the anti-immunization of stronger antiinflammatory.

Two, In vitro Bactericidal Experiments

Double broth dilution method is adopted to measure the minimum inhibitory concentration (MIC) of the present invention to common pathogen.Be inoculated in by tested bacterium in MH broth bouillon, cultivate after 18 hours for 35 DEG C, adjust the turbidity that its turbidity reaches 0.5 Maxwell opacity tube standard, bacterial content is about 108CFU/ml.With physiological saline solution dilution 1: 10 (bacteria containing amount is about 107CFU/ml).Get the medicinal liquid 2ml diluted for series concentration respectively to add and perform in the flat board of labelling, then the MH agar culture medium 18ml being chilled to about 50 DEG C after getting thawing be added to dull and stereotyped in (medicine: agar=1: 9) makes medicine and culture medium fully mix.Medicine ultimate density is respectively 200,100,50 ... 0.78,0.39mg/ml.Be inoculated on pastille flat board by the bacteria suspension inoculating loop prepared, cultivate 18 hours observed results in 35 DEG C, the lowest concentration of drug that colony growth is totally constrained is that this medicine is to the MIC detecting bacterium.Single bacteria growing can be ignored.Drug control and strain growth contrast are established in test simultaneously.The results are shown in Table 2.

Table 2 extracorporeal bacteria inhibitor test result

Bacterial strain	Minimum inhibitory concentration (MIC) (mg/ml)
		Shigella flexneri	4.315
Paratyphoid bacillus A	11.14
		Bacillus paratyphosus B	25.38
Bacillus pyocyaneus	5.87
		Escherichia coli	49.16
Bacillus enteritidis	23.25
		Staphylococcus aureus	6.98

As seen from Table 2, medicine of the present invention all has certain antibacterial action to shigella flexneri, paratyphoid bacillus A, Bacillus paratyphosus B, escherichia coli, bacillus pyocyaneus, staphylococcus aureus, bacillus enteritidis.

Illustrate: human intestines and stomach belongs to hollow organ, in the ordinary course of things, B ultrasonic is utilized can not well to show coat of the stomach level, the present invention assist Concha Margaritifera in video picture preparation and Qing Lang ?in calcium carbonate all containing certain ingredients, with in gastric acid and after can produce carbon dioxide bubble, and Chinese medicine of the present invention is when assisting video picture preparation to take or need the 100-300ml that drinks water after taking, obvious relieving gastric hyperacidity to alleviate stomachache effect is played after making various Chinese Medicine and Clavicular, more clear on image, the strong reecho of point-like, see that coat of the stomach clear layer is visible, and this auxiliary video picture preparation takes down, stomach week mucosa is played a protective role, ultrasound display screen can see gastral cavity size, form, cardia, pylorus, gastric antrum, duodenum, lesser gastric curvature, place's video pictures such as greater gastric curvature are obvious, each position focus is high-visible, and to perigastric organs as liver, gallbladder, pancreas display is clear, also can clarify a diagnosis to stomach week status of lymph node metastasis.What the present invention assisted video picture preparation helps shadow principle as follows: in the calcium carbonate in auxiliary video picture preparation and produce carbon dioxide bubble after gastric acid, drink water 100 ~ 300 milliliters and to swim phenomenon in " flakes " afterwards, because the stickum in auxiliary video picture preparation is to ulcer, cancerous protuberance mucomembranous surface can build up, be fused into rope block or light to clique graph and resemble, form obvious interface, because auxiliary video picture preparation can make gastral cavity fill the difference causing gastric wall mucus in acoustic impedance, thus display stomach form, position, gastral cavity size, wall of stomach thickness, emptying time and gastropathy place situation, gastrointestinal dysfunction can be shown, the pathological changes at display small intestinal, caecum, each position of colon.

The Chinese medicine that B ultrasonic of the present invention uses assists video picture preparation to be that video picture preparation assisted by pure Chinese medicine; no side effects; taking convenience; video picture is clear, strengthens the effect of gastric protective barrier, and diagnosis accurately; clinically take (wherein through 185 examples; 90 examples adopt the powder of the embodiment of the present invention 1, and 95 examples adopt the oral solutions of the embodiment of the present invention 2), various gastrointestinal disease of clarifying a diagnosis.Within oral this product 5-15 minute, stomach bubble can be got rid of, eliminate mucus and make the display of coat of the stomach structure clear, clear display stomach different lesions, imaging results is good, and resolving power is high, image stabilization, can gastric B ultrasonic examination inspection be carried out with various ordinary ultrasonography b instrument, and there is invigorating the stomach and promoting digestion, de-swelling analgesic effect.According to clinical diagnostic tests, excellent visualization ratio 95.8%, general visualization ratio 3.5%, can go out superficial gastritis, hypertrophic gastritis, prolapse of gastric mucosa, gastric cancer, pyloric part tumor, gastroptosis and duodenitis etc. by auxiliary diagnosis.

Concrete case:

Become certain, male, 50 years old.Patient once went to a doctor in ×× county people's hospital because of glutted after interruption stomachache and feed, pain aperiodicity and regularity, be diagnosed as " gastric ulcer ", and give antiinflammatory, antiacid treatment, but poor effect, rear symptom increases the weight of further, engender the symptoms such as appetite declines, weak, and with losing weight, melena.To our hospital, the contrast agent through the oral embodiment of the present invention 1 shows the visible low echo enclosed mass in gastric antrum place on B ultrasonic diagnostic screen, and the lymph node of stomach Zhou Kejian about 1.2cm, is diagnosed as gastric cancer.

All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.

The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (9)

1. video picture preparation assisted by a ultrasonic image diagnosis Chinese medicine; it is characterized in that, described Chinese medicine assists video picture preparation to comprise following raw medicinal material: Concha Margaritifera, Qing Lang ?, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris, Herba Morindae Parvifoliae, chondrus ocellatus Holmes, Folium desmoris, Herba Belladonnae, Herba Aletridis spicatae, Herba Stachydis, Herba Chelidonii, Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae.

2. video picture preparation assisted by ultrasonic image diagnosis Chinese medicine as claimed in claim 1, it is characterized in that, described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be: Concha Margaritifera 20 ~ 30 parts, Qing Lang ?20 ~ 30 parts, Semen Oroxyli 10 ~ 20 parts, Caulis Cucurbitae 15 ~ 25 parts, Phellinus igniarius (L. ex Fr.) Quel. 10 ~ 20 parts, Testa dolichoris 10 ~ 20 parts, Herba Morindae Parvifoliae 15 ~ 25 parts, chondrus ocellatus Holmes 5 ~ 15 parts, Folium desmoris 5 ~ 15 parts, Herba Belladonnae 5 ~ 15 parts, Herba Aletridis spicatae 10 ~ 20 parts, Herba Stachydis 10 ~ 20 parts, Herba Chelidonii 5 ~ 15 parts, Herba Limonii Gmelinii 30 ~ 40 parts, Fructus Rhodomyrti 15 ~ 25 parts, Caulis Kadsurae Coccineae 30 ~ 40 parts and Radix Tephrosiae purpureae 5 ~ 15 parts.

3. video picture preparation assisted by ultrasonic image diagnosis Chinese medicine as claimed in claim 1 or 2, it is characterized in that, described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be: Concha Margaritifera 20 ~ 25 parts, Qing Lang ?20 ~ 25 parts, Semen Oroxyli 10 ~ 15 parts, Caulis Cucurbitae 15 ~ 20 parts, Phellinus igniarius (L. ex Fr.) Quel. 10 ~ 15 parts, Testa dolichoris 10 ~ 15 parts, Herba Morindae Parvifoliae 15 ~ 20 parts, chondrus ocellatus Holmes 5 ~ 10 parts, Folium desmoris 5 ~ 10 parts, Herba Belladonnae 5 ~ 10 parts, Herba Aletridis spicatae 10 ~ 15 parts, Herba Stachydis 10 ~ 15 parts, Herba Chelidonii 5 ~ 10 parts, Herba Limonii Gmelinii 30 ~ 35 parts, Fructus Rhodomyrti 15 ~ 20 parts, Caulis Kadsurae Coccineae 30 ~ 35 parts and Radix Tephrosiae purpureae 5 ~ 10 parts.

4. video picture preparation assisted by the ultrasonic image diagnosis Chinese medicine as described in claims 1 to 3; it is characterized in that, described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be: Concha Margaritifera 22 parts, Qing Lang ?24 parts, Semen Oroxyli 13 parts, Caulis Cucurbitae 18 parts, Phellinus igniarius (L. ex Fr.) Quel. 11 parts, Testa dolichoris 14 parts, Herba Morindae Parvifoliae 16 parts, chondrus ocellatus Holmes 7 parts, Folium desmoris 8 parts, Herba Belladonnae 6 parts, Herba Aletridis spicatae 12 parts, Herba Stachydis 14 parts, Herba Chelidonii 6 parts, Herba Limonii Gmelinii 34 parts, Fructus Rhodomyrti 17 parts, Caulis Kadsurae Coccineae 31 parts and Radix Tephrosiae purpureae 8 parts.

5. video picture preparation assisted by the ultrasonic image diagnosis Chinese medicine as described in Claims 1-4; it is characterized in that, described Chinese medicine assists the ratio of weight and number of the various raw medicinal materials in video picture preparation to be: Concha Margaritifera 24 parts, Qing Lang ?21 parts, Semen Oroxyli 11 parts, Caulis Cucurbitae 16 parts, Phellinus igniarius (L. ex Fr.) Quel. 14 parts, Testa dolichoris 11 parts, Herba Morindae Parvifoliae 18 parts, chondrus ocellatus Holmes 6 parts, Folium desmoris 7 parts, Herba Belladonnae 7 parts, Herba Aletridis spicatae 14 parts, Herba Stachydis 12 parts, Herba Chelidonii 8 parts, Herba Limonii Gmelinii 32 parts, Fructus Rhodomyrti 19 parts, Caulis Kadsurae Coccineae 34 parts and Radix Tephrosiae purpureae 6 parts.

6. video picture preparation assisted by the ultrasonic image diagnosis Chinese medicine as described in claim 1 to 5, it is characterized in that, described Chinese medicine assists the dosage form of video picture preparation to be powder, and it comprises the following steps:

The first step, by Concha Margaritifera, Qing Lang ?, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris and Herba Morindae Parvifoliae mix in described ratio, with being the dissolve with ethanol of 85% ~ 95% relative to the determining alcohol of 3 ~ 5 times of mixture quality obtained, reflux was extracted after 2 ~ 4 hours, filter, obtain the first filtrate; By filtering residue again with the dissolve with ethanol of the determining alcohol 85% ~ 95% of 1 ~ 2 times relative to the mixture quality obtained, reflux was extracted after 1 ~ 2 hour, filtered, obtained the second filtrate; Merge the first filtrate and the second filtrate, decompression recycling ethanol to be concentrated into liquor strength be 0.7 ~ 0.9g crude drug/mL, through the macroporous adsorptive resins eluting that volume is 5L, first use deionized water or the distilled water eluting of 5 times of resin column volumes, be 90% ~ 95% ethanol elution with the determining alcohol of 3 times of resin column volumes again, collect ethanol elution, concentrating under reduced pressure removing ethanol, drying is also ground into powder;

Second step, Herba Chelidonii, Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae are mixed in described ratio, add the ethanol of the determining alcohol 85% ~ 95% of 2 ~ 4 times relative to the mixture quality obtained, heating and refluxing extraction 1 ~ 2 time, extracting solution merges, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the mastic of 1.20 ~ 1.23, and the mastic spray dryer after concentrated is dried to powder;

3rd step, mixes surplus stock medical material in described ratio, adds the water dissolution of 4 ~ 6 times relative to the mixture quality obtained, and heating decoction 2 ~ 4 hours, filters; By filtering residue again with the water dissolution of 2 ~ 4 times relative to the mixture quality obtained, again heat decoction 1 ~ 2 hour, filter; Merge the filtrate of twice, concentrating under reduced pressure removing moisture, drying is also ground into powder;

4th step, the powder mixing first step, second step and the 3rd step obtained, is screened into 100 ~ 200 object fine powders subsequently, is dropped in mixing and blending machine by the fine powder of acquisition and stirs, namely obtain described Chinese powder medicine.

7. video picture preparation assisted by the ultrasonic image diagnosis Chinese medicine as described in claim 1 to 5, it is characterized in that, when prepared dosage form is oral solutions, its preparation method comprises the following steps:

The first step, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris, Herba Morindae Parvifoliae, chondrus ocellatus Holmes, Folium desmoris, Herba Belladonnae, Herba Aletridis spicatae, Herba Stachydis and Herba Chelidonii are mixed in proportion rear pulverizing, be that the methanol of 75% ~ 85% is as solvent with determining alcohol, flood 20 ~ 50 hours, adopt percolation with the speed of 1 ~ 3ml per minute slowly percolation, collect percolate, concentrating under reduced pressure is also dry, obtain and get dry extract, be ground into powder, the quality of the methanol added is 3 ~ 5 times of first step mixture quality;

Second step, get the distilled water being equivalent to surplus stock medicinal material mixture quality 4 ~ 8 times, first by Concha Margaritifera and Qing Lang ?pulverize after, add in distilled water, decoct 1 ~ 2 hour, and then continue decoction 2 ~ 3 hours by adding in decoction liquor after the pulverizing of Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae, filter, obtain the first filtrate; Filtering residue is added the distilled water relative to its quality 2 ~ 4 times, decoct 1 ~ 3 hour, filter, obtain the second filtrate; Merge the first filtrate and the second filtrate, the water of concentrated removal 2/3 ~ 3/4 volume, adds the ethanol that determining alcohol is 85 ~ 95%, makes determining alcohol reach 70% ~ 80%, leaves standstill 12 ~ 24 hours, filters, concentrating under reduced pressure, dry, obtains and gets dry extract, be ground into powder;

3rd step, the powder mixing first step and second step obtained, add the distilled water relative to powder quality 3 ~ 5 times amount, the sucrose of 0.1 ~ 0.5 times, the sodium benzoate of 0.005 ~ 0.05 times, stir, boil, cooling, filter, subpackage, namely sterilizing obtains oral liquid.

8. a preparation method for video picture preparation assisted by the ultrasonic image diagnosis Chinese medicine as described in claim 1 to 5, it is characterized in that, described Chinese medicine assists the dosage form of video picture preparation to be powder, and it comprises the following steps:

The first step, by Concha Margaritifera, Qing Lang ?, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris and Herba Morindae Parvifoliae mix in described ratio, with being the dissolve with ethanol of 85% ~ 95% relative to the determining alcohol of 3 ~ 5 times of mixture quality obtained, reflux was extracted after 2 ~ 4 hours, filter, obtain the first filtrate; By filtering residue again with the dissolve with ethanol of the determining alcohol 85% ~ 95% of 1 ~ 2 times relative to the mixture quality obtained, reflux was extracted after 1 ~ 2 hour, filtered, obtained the second filtrate; Merge the first filtrate and the second filtrate, decompression recycling ethanol to be concentrated into liquor strength be 0.7 ~ 0.9g crude drug/mL, through the macroporous adsorptive resins eluting that volume is 5L, first use deionized water or the distilled water eluting of 5 times of resin column volumes, be 90% ~ 95% ethanol elution with the determining alcohol of 3 times of resin column volumes again, collect ethanol elution, concentrating under reduced pressure removing ethanol, drying is also ground into powder;

Second step, Herba Chelidonii, Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae are mixed in described ratio, add the ethanol of the determining alcohol 85% ~ 95% of 2 ~ 4 times relative to the mixture quality obtained, heating and refluxing extraction 1 ~ 2 time, extracting solution merges, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the mastic of 1.20 ~ 1.23, and the mastic spray dryer after concentrated is dried to powder;

3rd step, mixes surplus stock medical material in described ratio, adds the water dissolution of 4 ~ 6 times relative to the mixture quality obtained, and heating decoction 2 ~ 4 hours, filters; By filtering residue again with the water dissolution of 2 ~ 4 times relative to the mixture quality obtained, again heat decoction 1 ~ 2 hour, filter; Merge the filtrate of twice, concentrating under reduced pressure removing moisture, drying is also ground into powder;

4th step, the powder mixing first step, second step and the 3rd step obtained, is screened into 100 ~ 200 object fine powders subsequently, is dropped in mixing and blending machine by the fine powder of acquisition and stirs, namely obtain described Chinese powder medicine.

9. a preparation method for video picture preparation assisted by the ultrasonic image diagnosis Chinese medicine as described in claim 1 to 5, it is characterized in that, prepared dosage form is oral liquid, comprises the following steps:

The first step, Semen Oroxyli, Caulis Cucurbitae, Phellinus igniarius (L. ex Fr.) Quel., Testa dolichoris, Herba Morindae Parvifoliae, chondrus ocellatus Holmes, Folium desmoris, Herba Belladonnae, Herba Aletridis spicatae, Herba Stachydis and Herba Chelidonii are mixed in proportion rear pulverizing, be that the methanol of 75% ~ 85% is as solvent with determining alcohol, flood 20 ~ 50 hours, adopt percolation with the speed of 1 ~ 3ml per minute slowly percolation, collect percolate, concentrating under reduced pressure is also dry, obtain and get dry extract, be ground into powder, the quality of the methanol added is 3 ~ 5 times of first step mixture quality;

Second step, get the distilled water being equivalent to surplus stock medicinal material mixture quality 4 ~ 8 times, first by Concha Margaritifera and Qing Lang ?pulverize after, add in distilled water, decoct 1 ~ 2 hour, and then continue decoction 2 ~ 3 hours by adding in decoction liquor after the pulverizing of Herba Limonii Gmelinii, Fructus Rhodomyrti, Caulis Kadsurae Coccineae and Radix Tephrosiae purpureae, filter, obtain the first filtrate; Filtering residue is added the distilled water relative to its quality 2 ~ 4 times, decoct 1 ~ 3 hour, filter, obtain the second filtrate; Merge the first filtrate and the second filtrate, the water of concentrated removal 2/3 ~ 3/4 volume, adds the ethanol that determining alcohol is 85 ~ 95%, makes determining alcohol reach 70% ~ 80%, leaves standstill 12 ~ 24 hours, filters, concentrating under reduced pressure, dry, obtains and gets dry extract, be ground into powder;

3rd step, the powder mixing first step and second step obtained, add the distilled water relative to powder quality 3 ~ 5 times amount, the sucrose of 0.1 ~ 0.5 times, the sodium benzoate of 0.005 ~ 0.05 times, stir, boil, cooling, filter, subpackage, namely sterilizing obtains oral liquid.