CN104306613B - A kind of medicament and its application process for treating snore disease - Google Patents

A kind of medicament and its application process for treating snore disease Download PDF

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Publication number
CN104306613B
CN104306613B CN201410634224.8A CN201410634224A CN104306613B CN 104306613 B CN104306613 B CN 104306613B CN 201410634224 A CN201410634224 A CN 201410634224A CN 104306613 B CN104306613 B CN 104306613B
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medicament
snore disease
gained
boiled
disease
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CN104306613A (en
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陈树杰
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Runtian (Chongqing) Medical Technology Research Institute Co.,Ltd.
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陈树杰
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A61K36/835Aquilaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention belongs to pharmaceutical technology field, more particularly to a kind of medicament and its application process for treating snore disease, medicament is made of the fragrant tree veteran leaf 80-100g of tabernaemontanus bulrush, natural borneol perfume (or spice) 2-4g, Ilex Latifolia Thunb 4-10g, rhizoma pinellinae praeparata 20g, artemisia seed gum 1g, gellan gum 0.06g, through parch, boil, distill, mix, adjust pH value to 4.3, filling be made, and inject in luffa cavernous body and make mask mode application, snore disease and dry mouth symptom can be released rapidly.

Description

A kind of medicament and its application process for treating snore disease
Technical field
The invention belongs to pharmaceutical technology field, more particularly to a kind of medicament and its application process for treating snore disease.
Background technology
Snore disease, also known as snores, sleep apnea syndrome, it not only influences other people and sleeps, it is often more important that, suffer from Person can induce the serious diseases such as hypertension, brain worry, miocardial infarction, angina pectoris because of anoxic, at present, except can use snore stopper and Outside lung ventilator class product, the effect of medicine is still unsatisfactory, and mainly side effect is larger or effect is not ideal enough, and snore stopper or Lung ventilator is for serious snore disease patient, though having mitigated to symptom, but still may not necessarily reach the effect that snore disease is completely eliminated Fruit.
The content of the invention
To overcome the problems of the above-mentioned prior art and deficiency, the present inventor is by concentrating on studies and testing, with natural Safe materials prescription, be made a kind of and treat the medicament of snore disease, and coordinate corresponding application process, make the effect for the treatment of snore disease big It is big to improve, take effect rapid, and have the function of safety, fragrant, the characteristics of calming the nerves and, complete the present invention.
The present invention is achieved by the following technical solutions:
A kind of medicament and its application process for treating snore disease, it is characterised in that the preparation method of the medicament, including with Lower preparation process:
(1)Weigh the raw material of following parts by weight:
The fragrant tree veteran leaf 80-100g of tabernaemontanus bulrush
Natural borneol perfume (or spice) 2-4g
Ilex Latifolia Thunb 4-10g
Rhizoma pinellinae praeparata 20g
Artemisia seed gum 1g
Gellan gum 0.06g;
(2)Rhizoma pinellinae praeparata plus water 500ml are boiled into 30min, remove slag taking juice, with atomizers spray to the fragrant tree veteran leaf of tabernaemontanus bulrush On, rubbing is uniform, then clear-cut to leaf with 190 DEG C of parch when placement 1 is small;
(3)By step(2)Gained adds 600ml water, and 30min is boiled in heating, and 200 mesh filter screens filter off slag, and it is spare to obtain liquid, And it is spare that distillate 100ml is collected while boiling;
(4)Ilex Latifolia Thunb plus water 300ml are boiled into 15min, tea grounds is filtered off, obtains bitter leaves tea liquid;
(5)By step(3)The liquid and step of middle gained(4)The bitter leaves tea liquid mixing of gained, adds artemisia seed gum and knot Cold glue, quickly stirs evenly, and boils and is concentrated into 400ml, when being cooled to 65 DEG C, adds step(3)The distillate of middle gained, then will Add, stir evenly after natural borneol perfume (or spice) pulverization, be adjusted to PH4.3 with fresh squeezing lemon juice, filling in 30ml volumetric flasks, envelope Mouthful, a kind of medicament for treating snore disease is made;
Its application process, comprises the following steps:
(1)Take 1 bottle of the medicament for the treatment of snore disease obtained above(30ml)Injection one kind uses silk made of natural loofah Melon network cavernous body(Select low density bulk type)It is interior, and luffa cavernous body is pressed repeatedly, medicament is uniformly dispersed and is adsorbed In luffa cavernous body;
(2)The luffa cavernous body of the disease medicament of adsorbing therapy snore directly as the mode of mask or is installed on only Allow snore disease patient to wear on the mask of snore function, allow patient to absorb the drug in breathing, it is rapid to release snore disease symptom.
Beneficial effects of the present invention are as follows:
The effective efficiency composition and fragrance ingredient that the fragrant tree veteran leaf of tabernaemontanus bulrush is accumulated due to the extension with growth time all can Increase, therefore select veteran leaf effect more preferable, there is fragrance, calm the nerves, tonify the kidney to improve inspiration, relievining asthma, the present invention is main to be utilized It improves the effect of sleep quality.
The fat symptom that can directly aggravate snore disease of human body, the traditional Chinese medical science is considered caused by damp evil cohesion, and natural borneol is fragrant (Also known as natural borneol)With the clear key of the wet illiteracy for the treatment of, larynx numbness, tongue is swollen, the performance of nasal polyp, and the present invention is exactly to utilize itself and method partly Summer compounds and reaches phlegm wet, has one's ideas straightened out to make the convergence of bottleneck throat soft tissue, recover lifting strength, so that airway unobstructed.
Ilex Latifolia Thunb sweet and cool-natured promotes the production of body fluid and can be clearing heat and detoxicating, throat can be made to feel as snug as a bug in a rug.
Artemisia seed gum contains pectic substance and cellulose, and tool forms a kind of polysaccharide material with cross-linked structure, can inhale decades of times Water and be swelled into egg white sample colloid, form tridimensional network in colloid, and gellan gum has a good Flavor release, two kinds Adsorpting formulation but also three-dimensional netted stabilization bubble cavernous structure can be produced after colloid is compound, be conducive to increase emission surface Product makes medicament play the function for the treatment of snore disease by absorption by human body respiration process, with lemon juice tune pH value to 4.3, Product is set also to can reach the purpose guaranteed the quality and preserved without heat sterilization, and smell is more fragrant.
The present invention is used made of natural loofah in luffa cavernous body, by anti-using the injection of above-mentioned medicament is a kind of Luffa cavernous body is pressed again, medicament is uniformly dispersed and is adsorbed in luffa cavernous body, since medicament has shape again in itself Into the performance of stable bubble cavernous structure so that effective release area of medicament greatly increases, with the form or peace of mask Loaded on having the function of on the mask of snore relieving, acted on by human body respiration process by absorption to play treatment snore disease(" the luffa Cavernous body " and " having the function of the mask of snore relieving " refer to another application for a patent for invention of the present inventor:A kind of " Multifunctional mouth Cover ", applicant:Chen Shujie).Its water content can exempt feeling bad for mouth parched and tongue scorched again.
Embodiment
Below by embodiment, the invention will be further described.
Embodiment.
Preferably, a kind of preparation method for the medicament for treating snore disease, including following preparation process:
(1)Weigh the raw material of following parts by weight:
The fragrant tree veteran leaf 90g of tabernaemontanus bulrush
Natural borneol perfume (or spice) 3g
Ilex Latifolia Thunb 7g
Rhizoma pinellinae praeparata 20g
Artemisia seed gum 1g
Gellan gum 0.06g;
(2)Rhizoma pinellinae praeparata plus water 500ml are boiled into 30min, remove slag taking juice, with atomizers spray to the fragrant tree veteran leaf of tabernaemontanus bulrush On, rubbing is uniform, then clear-cut to leaf with 190 DEG C of parch when placement 1 is small;
(3)By step(2)Gained adds 600ml water, and 30min is boiled in heating, and 200 mesh filter screens filter off slag, and it is spare to obtain liquid, And it is spare that distillate 100ml is collected while boiling;
(4)Ilex Latifolia Thunb plus water 300ml are boiled into 15min, tea grounds is filtered off, obtains bitter leaves tea liquid;
(5)By step(3)The liquid and step of middle gained(4)The bitter leaves tea liquid mixing of gained, adds artemisia seed gum and knot Cold glue, quickly stirs evenly, and boils and is concentrated into 400ml, when being cooled to 65 DEG C, adds step(3)The distillate of middle gained, then will Add, stir evenly after natural borneol perfume (or spice) pulverization, PH 4.3 is adjusted to fresh squeezing lemon juice, it is filling in 30ml volumetric flasks, Sealing, is made a kind of medicament for treating snore disease;
Its application process, comprises the following steps:
(1)Take 1 bottle of injection of medicament for the treatment of snore disease obtained above is a kind of to use luffa sea made of natural loofah Continuous body(Select low density bulk type)It is interior, and luffa cavernous body is pressed repeatedly, medicament is uniformly dispersed and be adsorbed in sponge gourd In network cavernous body;
(2)The luffa cavernous body of the disease medicament of adsorbing therapy snore directly as the mode of mask or is installed on only Allow snore disease patient to wear on the mask of snore function, allow patient to absorb the drug in breathing, it is rapid to release snore disease symptom.
Verify example 1.
It is supplied to 20 snore disease patients to make mask mode product of the present invention to use, first using effective percentage 80%, uses 1 Effective percentage 95% after a month, but dehisce in alleviation that to feel bad aspect efficient up to 100% for dry caused by air-breathing.
Verify example 2.
It is supplied to 20 snore disease patients to be installed on " a kind of Multifunctional gauze mask " product of the present invention(Also for the present inventor's The product of another application for a patent for invention)In use at the same time, and be comfortable on, sleep quality up to 100% using effective percentage first Greatly improve.
Embodiment described above only expresses the better embodiment of the present invention, but can not therefore be interpreted as to this The limitation of patent of invention scope, the protection domain of patent of the present invention should be determined by the appended claims.

Claims (1)

1. a kind of medicament for treating snore disease, it is characterised in that the preparation method of the medicament, including following preparation process:
(1)Weigh the raw material of following parts by weight:
The fragrant tree veteran leaf 80-100g of tabernaemontanus bulrush
Natural borneol perfume (or spice) 2-4g
Ilex Latifolia Thunb 4-10g
Rhizoma pinellinae praeparata 20g
Artemisia seed gum 1g
Gellan gum 0.06g;
(2)Rhizoma pinellinae praeparata plus water 500ml are boiled into 30min, remove slag taking juice, is set with atomizers spray to tabernaemontanus bulrush is fragrant on veteran leaf,
Rubbing is uniform, then clear-cut to leaf with 190 DEG C of parch when placement 1 is small;
(3)By step(2)Gained adds 600ml water, and 30min is boiled in heating, and 200 mesh filter screens filter off slag, and it is spare to obtain liquid, and It is spare that distillate 100ml is collected while boiling;
(4)Ilex Latifolia Thunb plus water 300ml are boiled into 15min, tea grounds is filtered off, obtains bitter leaves tea liquid;
(5)By step(3)The liquid and step of middle gained(4)The bitter leaves tea liquid mixing of gained, adds artemisia seed gum and gellan gum, Quickly stir evenly, boil and be concentrated into 400ml, when being cooled to 65 DEG C, add step(3)The distillate of middle gained, then will be natural Add, stir evenly after kapur pulverization, PH4.3 is adjusted to fresh squeezing lemon juice, filling in 30ml volumetric flasks, sealing, A kind of medicament for treating snore disease is made.
CN201410634224.8A 2014-11-12 2014-11-12 A kind of medicament and its application process for treating snore disease Active CN104306613B (en)

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CN201410634224.8A CN104306613B (en) 2014-11-12 2014-11-12 A kind of medicament and its application process for treating snore disease

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Application Number Priority Date Filing Date Title
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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104706869A (en) * 2015-03-25 2015-06-17 王玉仙 External traditional Chinese medicine powder for treating snore
CN112294052A (en) * 2019-07-15 2021-02-02 河南省蚕业科学研究院 Traditional Chinese medicine pillow for removing obstruction and stopping snore

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101040999A (en) * 2006-03-23 2007-09-26 吴洵邦 Medicine compound for treating snoring and the preparing method and the quality control method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101040999A (en) * 2006-03-23 2007-09-26 吴洵邦 Medicine compound for treating snoring and the preparing method and the quality control method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
中药治愈打呼噜;中华秘方网;《http://www.zhmf5.com/2014/05/10935.html》;20140529;第1页诊断及处方 *

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Effective date of registration: 20210513

Address after: 400000 2-3, 2-4, 12 Nanbin Road, Nan'an District, Chongqing

Patentee after: Runtian (Chongqing) Medical Technology Research Institute Co.,Ltd.

Address before: 523320 room 509, weaving basket street, Shilong Town, Dongguan, Guangdong, 509

Patentee before: Chen Shujie

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