CN103229870A - Depression-resolving health-care tea for preventing and treating depressive disorder and production method of health-care tea - Google Patents
Depression-resolving health-care tea for preventing and treating depressive disorder and production method of health-care tea Download PDFInfo
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Abstract
The invention relates to depression-resolving health-care tea for preventing and treating depressive disorder and a production method of the health-care tea, and is used for effectively solving the problem of prevention and treatment of the depressive disorder. The method comprises the steps of mixing the materials of tea, monthly rose, peony, jasmine, ginseng leaf, fruit of Chinese wolfberry and dogwood according to the weight ratio of (1-2) to (1-6) to (1-3) to (1-3) to (1-4) to (1-6) to (1-4), crushing the materials into powder as the materials, adding water which is 2-3 folds of the materials to decoct for 10-60 minutes at 80-100 DEG C, filtering to obtain filtrate, and adding water which is 1.5-2 folds of the materials to filter residue to decoct for 10-60 minutes; filtering and merging twice filtrate, and then concentrating until the relative density is 1.5 at 60 DEG C to prepare the fluid extract; and preparing different tastes of health-care tea from water, a sour agent, a spice and a sweetening agent by a common method; or crushing the tea, the monthly rose, the peony, the jasmine, the ginseng leaf, the fruit of Chinese wolfberry and the dogwood into powder, and then packaging into bags. The depression-resolving health-care tea is abundant in materials, low in cost, easy to produce and drink, and good in effect, and is effectively used for preventing and treating the depressive disorder.
Description
Technical field
The present invention relates to health drink, particularly a kind of strongly fragrant health protection tea of solution and production method thereof of preventing and treating depression.
Background technology
Depression be with remarkable and lasting depressed, behavior is numb and pessimistic and worldweary be his one group of disease of principal character.In fact it is very common, so that is called as " common cold " in the mental illness, and it still is serious, life-threatening disease simultaneously, is tormenting the people who counts in the world in necessarily.The medicine that is used for the treatment of depression at present mainly contains tricyclic antidepressants, MAOI and serotonin reuptake inhibitor, but side effect is in various degree arranged all, as drowsiness, blurred vision, hypertension, convulsions and hyposexuality etc., clinical in the not effective in cure good and medicine that has no side effect as yet.
Traditional Chinese medicine and pharmacy is a big treasure-house, the treatment various diseases has unique distinction, depression incidence of disease height (wherein liver qi stagnation type, qi stagnation and blood stasis type, three warmers stagnated fire type, liver gallbladder damp-heat type, type of deficiency of both QI and YIN, liver-kidney yin deficiency are common depression card type), and social danger is big, but lacks the open report of the strongly fragrant health-care tea beverage of preventing and treating at depression of solution so far.
Summary of the invention
At above-mentioned situation, for overcoming the defective of prior art, the present invention's purpose is to provide a kind of salubrious Yin enriching heath care tea and production method thereof of preventing and treating depression, can effectively solve the problem of preventing and treating of depression.
The technical scheme that the present invention solves is, this health protection tea is made by tealeaves, China rose, peony, cape jasmine, folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni, and its weight ratio is:
Cha Ye ︰ month Ji Hua ︰ Mu Dan Hua ︰ Zhi ︰ Ren Can Ye ︰ Gou Qi ︰ Fructus Corni=1～2 ︰, 1～6 ︰, 1～3 ︰, 1～3 ︰, 1～4 ︰, 1～6 ︰ 1～4;
Described tealeaves is a kind of of green tea, black tea or jasmine tea; Described green tea is a kind of of high-quality green tea, Pilochun (a green tea), Dragon Well tea, green bamboo snake etc.; Described black tea is red etc. a kind of in keemun, Yunnan black tea, Fujian; Described jasmine tea is a kind of of Jasmine, rose, Hunan scented tea, lily etc.;
Its preparation method is:
The powdery that is broken into granularity≤1.5mm according to tealeaves, China rose, peony, cape jasmine, folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni mixed powder is made raw material, 2～3 times the water that adds raw material weight then, boil 10-60 min at 80～100 ℃, filter to get filtrate, filter residue adds 1.5～2 times poach 10-60 min of raw material weight again, filter, merge filtrate twice, be concentrated into 60 ℃ of following relative densities 1.5 then, be prepared into liquid extract, with method and water, acid, spices and the sweetener of routine, the health protection tea of making different taste is packaged into bottle, pop can again; Or tealeaves, China rose, peony, cape jasmine, folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni be ground into the powdery of granularity≤1.5mm, and be packaged into bag, when drinking, add boiling water and soak and take.
Can be made into the health protection tea that prevents and treats depression of any amount by above-mentioned prescription and method.
Abundant raw material of the present invention, cost is low, easily produces and drinks, and is effective, is effective to the problem of preventing and treating of depression.
The specific embodiment
Elaborate below in conjunction with the specific embodiment of the present invention of embodiment.
Embodiment 1
The present invention is in concrete enforcement, be to make: Hong Cha ︰ month Ji Hua ︰ Mu Dan Hua ︰ Zhi ︰ Ren Can Ye ︰ Gou Qi ︰ Fructus Corni=1.5 ︰, 3.5 ︰, 2 ︰, 2 ︰, 2.5 ︰, 3.5 ︰ 2.5 by the raw material of following weight ratio, with black tea, China rose, peony, cape jasmine, the folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni mixed powder are broken into the powdery of granularity≤1.5mm and make raw material, 3 times the water that adds raw material weight then, be heated to 100 ℃ and boil 20 min, filter to get filtrate, filter residue adds 2 times poach 15 min of raw material weight again, filter, merge filtrate twice, be concentrated into 60 ℃ of following relative densities 1.5 then, be prepared into liquid extract, again with method and the water of routine, acid, spices and sweetener, the health protection tea of making different taste is packaged into bottle, pop can; Or black tea, China rose, peony, cape jasmine, folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni be ground into the powdery of granularity≤1.5mm, and be packaged into bag, when drinking, add boiling water and soak and take.
Embodiment 2
The present invention is in concrete enforcement, also can make: Hua Cha ︰ month Ji Hua ︰ Mu Dan Hua ︰ Zhi ︰ Ren Can Ye ︰ Gou Qi ︰ Fructus Corni=2 ︰, 6 ︰, 3 ︰, 3 ︰, 4 ︰, 6 ︰ 4 by the raw material of following weight ratio, with jasmine tea, China rose, peony, cape jasmine, the folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni mixed powder are broken into the powdery of granularity≤1.5mm and make raw material, 3 times the water that adds raw material weight then, be heated to 100 ℃ and boil 20 min, filter to get filtrate, filter residue adds 2 times poach 15 min of raw material weight again, filter, merge filtrate twice, be concentrated into 60 ℃ of following relative densities 1.5 then, be prepared into liquid extract, again with method and the water of routine, acid, spices and sweetener, the health protection tea of making different taste is packaged into bottle, pop can; Or jasmine tea, China rose, peony, cape jasmine, folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni be ground into the powdery of granularity≤1.5mm, and be packaged into bag, when drinking, add boiling water and soak and take.
Embodiment 3
The present invention is in concrete enforcement, be to make: Lv Cha ︰ month Ji Hua ︰ Mu Dan Hua ︰ Zhi ︰ Ren Can Ye ︰ Gou Qi ︰ Fructus Corni=1 ︰, 1 ︰, 1 ︰, 1 ︰, 1 ︰, 1 ︰ 1 by the raw material of following weight ratio, with green tea, China rose, peony, cape jasmine, the folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni mixed powder are broken into the powdery of granularity≤1.5mm and make raw material, 3 times the water that adds raw material weight then, be heated to 100 ℃ and boil 20 min, filter to get filtrate, filter residue adds 2 times poach 15 min of raw material weight again, filter, merge filtrate twice, be concentrated into 60 ℃ of following relative densities 1.5 then, be prepared into liquid extract, again with method and the water of routine, acid, spices and sweetener, the health protection tea of making different taste is packaged into bottle, pop can; Or green tea, China rose, peony, cape jasmine, folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni be ground into the powdery of granularity≤1.5mm, is packaged into bag, when drinking, adds boiling water and soak and take.
The applicant it is to be noted that above-described embodiment is interpreted as only being used for explanation the present invention and is not used in restriction protection scope of the present invention.After the content of having read the present invention's record, those skilled in the art can make various changes or modifications the present invention, and these equivalences change and modify and fall into claim of the present invention institute restricted portion equally.
In said medicine, wherein China rose (is the rosaceous plant Chinese rose
Rosa chinesisJacq. dried floral, the sweet temperature of the property of medicine) and peony (be Paeoniaceae plant tree peony
Paeonia suffruticosaAndr. dried floral, the property of medicine is light flat), the two all returns Liver Channel, has the effect of soothing liver-qi stagnation, promoting blood circulation for regulating menstruation, is mainly used in treatment of diseases such as stagnation of liver qi, stagnation of QI and blood; Folium panacis japonici cum caule's Araliaceae genseng
Panax ginsengC. the dried leaves of A. Mey., the property of medicine is sweet cold, attaches to the lung and stomach meridians, and the effect of have tonifying Qi, beneficial lung, driving away summer heat, promoting the production of body fluid is mainly used in the treatment of syndrome of deficiency of both qi and yin; Cape jasmine is the madder wort cape jasmine
Gardenia jasminoidesThe dry mature fruit of Ellis, property of medicine hardship, cold, the thoughts of returning home, lung, tri-jiao channel have the effect of purging intense heat relieving restlessness, clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body, are mainly used in that pyreticosis is vexed, three warmers stagnated fire, liver and gallbladder damp-heat, heat poison card etc.; The fruit of Chinese wolfberry is the plant of Solanaceae lycium barbarum
Lycium barbarumL. ripening fruits, the property of medicine is sweet, flat, returns liver, kidney channel, has effect nourishing liver and kidney, benefiting shrewd head, is used for syndrome of yin deficiency of liver and kidney; Fructus Corni is Cornaceae plant Fructus Corni
Cornus officinalisThe drying and ripening pulp of Sieb.et Zucc., property of medicine acid, puckery, tepor, return liver, kidney channel, have tonify the liver and kidney, the effect of arresting collape syndrome by astringents, be used for dizzy ear toot, under the soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, uterine bleeding band, profuse sweating collapse, interior heat card such as quench one's thirst.
Depression is neurosal a kind of, reduces with hypothymergasia, retardation of thinking and speech action.A joint study of the World Health Organization, the World Bank and Harvard University shows that depression has become second serious disease of Chinese disease burden.The factor that causes depression comprises: inherent cause, physical factors, mental element etc.
The present invention is the strongly fragrant health protection tea of solution that primary raw material is made with China rose, peony, cape jasmine, folium panacis japonici cum caule, the fruit of Chinese wolfberry, Fructus Corni first, brought into play simultaneously the soothing liver-qi stagnation of China rose and peony and alleviating mental depression, cape jasmine heart fire-clearing upset-relieving, clear three warmers stagnated fire solution is strongly fragrant and the dampness removing solution is strongly fragrant, folium panacis japonici cum caule's supplementing qi and nourishing yin solution is strongly fragrant, the filling liver kidney solution of the fruit of Chinese wolfberry and Fructus Corni is strongly fragrant, can be used for preventing and treating polytype depression such as liver qi stagnation type common in clinical, qi stagnation and blood stasis type, three warmers stagnated fire type, type of deficiency of both QI and YIN, liver-kidney yin deficiency, liver gallbladder damp-heat type.In addition, folium panacis japonici cum caule and the cape jasmine property of medicine cold and cool partially and China rose and Fructus Corni be temperature partially, and peony and the fruit of Chinese wolfberry are levelling, and the prescription of whole tea is bordering on levelling, the drawback of having avoided the cold or inclined to one side partially temperature of long-term drinking to injure one's stomach; Selected material medicine majority has sugariness simultaneously, lays a good foundation for this tea set has better mouthfeel, is effective to the control of depression, and through experiment, it prevents and treats the remarkably productive of depression, uses product of the present invention through some patients with depression, has played tangible health care and auxiliary curing effect; Simultaneously product of the present invention is applied to the antidepression zoopery, the result shows that product antidepressant effect of the present invention is remarkable.While product comfortable taste of the present invention, fragrant odour.The great advantage of product of the present invention is without any side effects, can be used as the beverage long-term drinking.
Relevant experimental data is as follows:
Mouse tail suspension experiment (tail suspension test, TST) and forced swimming experiment (forced swim test, FST) all be that the checking medicine has antidepressant effect zoopery commonly used, so the present invention at first verifies that with it this health protection tea product is to the preventive and therapeutic effect of experimental animal models depression.Since the medicine with central excitation effect TST or (with) also may show as positive findings in the FST experiment, (open field test OFT) can get rid of this false-positive situation and open wild experiment.Therefore, the present invention has investigated this health protection tea product subsequently in the situation of OFT experiment, with the science of guaranteeing to verify the result, reliable.
1.1 experiment material
1.1.1 animal subject
Kunming (KM) mouse, ♂, body weight 18～22 g, [SCXK (Henan) 2010-0002] provides by Henan Province's Experimental Animal Center.
Be health protection tea of the present invention 1.1.2 try article
1.2 experimental technique
1.2.1 TST experiment
Adopt the KM male mice, body weight 18～22 g, 10 every group.Positive drug Fluoxetine hydrochloride (Fluoxetine hydrochloride, FH) and TA, TB, TC, TD, TE, TF all with 0.5% CMC-Na dissolving or be suspended to required administration concentration, FH dosage 0.01 g/kg, TA, TB, TC, TD, TE, TF dosage are all with 6 g/kg, model group (CMC-Na) gives 0.5% CMC-Na of equal volume, each organizes equal continuous irrigation stomach (ig) administration 7 days, once a day, tests behind last administration 1 h.Method of testing is as follows.
Single mouse tail end (at 2 cm places, distance tail tip) is sticked at adhesive plaster on outstanding boot (30 cm * 30 cm * 25 cm) upper bracket, make it become the reversal of the natural order of things state, head about 5 cm at the bottom of the case once hang 2 mouse, middlely separate with dividing plate.Mouse struggle activity in order to overcome undesired position, but that discontinuity appears in movable a period of time is motionless, shows disappointed state.The suspension time is 6 min, the outstanding tail accumulative total dead time in 4 min of statistics back (motionless state is that mouse stops to struggle motionless or do not have any activity).
1.2.2 FST experiment
Adopt the KM male mice, body weight 18～22 g, 10 every group.Positive drug FH and TA, TB, TC, TD, TE, TF are all with 0.5% CMC-Na dissolving or be suspended to required administration concentration, FH dosage 0.01 g/kg, TA, TB, TC, TD, TE, TF dosage are all with 6 g/kg, model group (CMC-Na) gives 0.5% CMC-Na of equal volume, each organizes equal continuous irrigation stomach (ig) administration 7 days, once a day, test behind last administration 1 h.Method of testing is as follows.
Mouse is put into the cylindrical glass cylinder of high 20 cm, diameter 14 cm separately, the depth of water 10 cm in the cylinder, water temperature (25 ± 2) ℃, timing 6 min after the mouse entry, the swimming accumulative total dead time in 4 min of record back (refers to that mouse stops to struggle in water, or apparent floating state, only have small limb motion to keep afloat to keep head).
1.2.3 OFT experiment
Adopt the KM male mice, body weight 18～22 g, 10 every group.Positive drug FH and TA, TB, TC, TD, TE, TF are all with 0.5% CMC-Na dissolving or be suspended to required administration concentration, FH dosage 0.01 g/kg(is with 0.5% CMC-Na suspendible), TA, TB, TC, TD, TE, TF dosage are all with 6 g/kg, model group (CMC-Na) gives 0.5% CMC-Na of equal volume, each organizes equal continuous irrigation stomach (ig) administration 7 days, once a day, test behind last administration 1 h.Method of testing is as follows.
Spacious case apparatus is the wooden case that length and width each 50 cm, high 25 cm, bottom surface are divided into 25 equilateral grids, and inner face is expired with pitch-dark being coated with.Quietly carrying out this experimental observation in the room.Mouse is put into the center grid, and the observed and recorded mouse was worn the lattice number of times in 3 minutes.
1.3 experimental result
As shown in table 1, compare with model group, all significantly reductions of the dead time that reaches FST of TA, TB, TC, TD, TE, TF and FH group mouse TST (
P＜0.05), and with TB and TE reduce the most obviously (extremely significantly reduce,
P＜0.01).This experimental result shows that health protection tea of the present invention all has the effect of control animal depression, and also suitable with the FH effect.
Mouse OFT wears each group of lattice number of times difference of comparing that there are no significant, got rid of may because of the central excitation effect bring TST or (with) false-positive situation in the FST experiment, show the science as a result, reliable of the health protection tea control experimental depression effect among the present invention.
Table 1 health protection tea to mouse TST/FST dead time and OFT wear the lattice number of times influence (n=10,
± s)
| Group | Dosage (g/kg) | The TST dead time (s) | The FST dead time (s) | OFT wears lattice number of times (inferior) |
| Model group (CMC-Na) | ? | 87.3 ± 25.1 | 100.6 ± 28.5 | 84.8 ± 23.9 |
| Positive group (FH) | 0.01 | 58.5 ± 17.4** | 67.4 ± 18.2** | 81.2 ± 21.3 |
| TA | 6 | 74.6 ± 21.9* | 79.5 ± 19.6* | 86.8 ± 25.6 |
| TB | 6 | 60.2 ± 18.1** | 72.4 ± 18.6** | 79.2 ± 20.5 |
| TC | 6 | 72.7 ± 22.2* | 82.9 ± 22.3* | 83.1 ± 24.8 |
| TD | 6 | 70.6 ± 23.7* | 83.7 ± 21.9* | 78.9 ± 23.1 |
| TE | 6 | 62.0 ± 19.5** | 70.7 ± 17.1** | 85.1 ± 25.5 |
| TF | 6 | 69.3 ± 21.8* | 80.2 ± 20.5* | 82.2 ± 22.3 |
Compare * with model group
P＜0.05, * *
P＜0.01
Above-mentioned test can clearly show, the invention discloses the health protection tea that prevents and treats depression, can be used for preparing antidepression health protection tea safely and efficiently and prevents and treats the application of depression health protection tea as preparation, and creative contribution is made in the development that is applied to health protection tea for traditional Chinese medicine.
Claims (5)
1. the strongly fragrant health protection tea of solution that prevents and treats depression is characterized in that, makes by spending ︰ Mu Dan flower ︰ Cape jasmine ︰ people to join the sub-︰ Fructus Corni of leaf ︰ Chinese holly Qi=1～2 ︰, 1～6 ︰, 1～3 ︰, 1～3 ︰, 1～4 ︰, 1～6 ︰ 1～4 in the tea leaf ︰ season month of following weight ratio meter;
Described tealeaves is a kind of of green tea, black tea or jasmine tea.
2. the described preparation method who prevents and treats the strongly fragrant health protection tea of solution of depression of claim 1, it is characterized in that, the powdery that Cha Ye ︰ month Ji Hua ︰ Mu Dan Hua ︰ Zhi ︰ Ren Can Ye ︰ Gou Qi ︰ Fructus Corni=1～2 ︰, 1～6 ︰, 1～3 ︰, 1～3 ︰, 1～4 ︰, 1～6 ︰, 1～4 mixed powder of following weight ratio is broken into granularity≤1.5mm is made raw material, 2～3 times the water that adds raw material weight then, boil 10-60 min at 80～100 ℃, filter to get filtrate, filter residue adds 1.5～2 times poach 10-60 min of raw material weight again, filter, merge filtrate twice, be concentrated into 60 ℃ of following relative densities 1.5 then, be prepared into liquid extract, again with method and the water of routine, acid, spices and sweetener, the health protection tea of making different taste is packaged into bottle, pop can; Or tealeaves, China rose, peony, cape jasmine, folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni be ground into the powdery of granularity≤1.5mm, be packaged into bag.
3. the preparation method who prevents and treats the strongly fragrant health protection tea of solution of depression according to claim 2, it is characterized in that, the powdery that is broken into granularity≤1.5mm by Hong Cha ︰ month Ji Hua ︰ Mu Dan Hua ︰ Zhi ︰ Ren Can Ye ︰ Gou Qi ︰ Fructus Corni=1.5 ︰, 3.5 ︰, 2 ︰, 2 ︰, 2.5 ︰, 3.5 ︰, 2.5 mixed powders of following weight ratio is made raw material, 3 times the water that adds raw material weight then, be heated to 100 ℃ and boil 20 min, filter to get filtrate, filter residue adds 2 times poach 15 min of raw material weight again, filter, merge filtrate twice, be concentrated into 60 ℃ of following relative densities 1.5 then, be prepared into liquid extract, again with method and the water of routine, acid, spices and sweetener, the health protection tea of making different taste is packaged into bottle, pop can; Or black tea, China rose, peony, cape jasmine, folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni be ground into the powdery of granularity≤1.5mm, be packaged into bag.
4. the preparation method who prevents and treats the strongly fragrant health protection tea of solution of depression according to claim 2, it is characterized in that, the powdery that is broken into granularity≤1.5mm by Hua Cha ︰ month Ji Hua ︰ Mu Dan Hua ︰ Zhi ︰ Ren Can Ye ︰ Gou Qi ︰ Fructus Corni=2 ︰, 6 ︰, 3 ︰, 3 ︰, 4 ︰, 6 ︰, 4 mixed powders of following weight ratio is made raw material, 3 times the water that adds raw material weight then, be heated to 100 ℃ and boil 20 min, filter to get filtrate, filter residue adds 2 times poach 15 min of raw material weight again, filter, merge filtrate twice, be concentrated into 60 ℃ of following relative densities 1.5 then, be prepared into liquid extract, again with method and the water of routine, acid, spices and sweetener, the health protection tea of making different taste is packaged into bottle, pop can; Or jasmine tea, China rose, peony, cape jasmine, folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni be ground into the powdery of granularity≤1.5mm, be packaged into bag.
5. the preparation method who prevents and treats the strongly fragrant health protection tea of solution of depression according to claim 2, it is characterized in that, the powdery that is broken into granularity≤1.5mm by Lv Cha ︰ month Ji Hua ︰ Mu Dan Hua ︰ Zhi ︰ Ren Can Ye ︰ Gou Qi ︰ Fructus Corni=1 ︰, 1 ︰, 1 ︰, 1 ︰, 1 ︰, 1 ︰, 1 mixed powder of following weight ratio is made raw material, 3 times the water that adds raw material weight then, be heated to 100 ℃ and boil 20 min, filter to get filtrate, filter residue adds 2 times poach 15 min of raw material weight again, filter, merge filtrate twice, be concentrated into 60 ℃ of following relative densities 1.5 then, be prepared into liquid extract, again with method and the water of routine, acid, spices and sweetener, the health protection tea of making different taste is packaged into bottle, pop can; Or green tea, China rose, peony, cape jasmine, folium panacis japonici cum caule, the fruit of Chinese wolfberry and Fructus Corni be ground into the powdery of granularity≤1.5mm, is packaged into bag.
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| CN104171103A (en) * | 2014-07-08 | 2014-12-03 | 河南中医学院 | Tonic blood glucose-reducing and depression-relieving tea for preventing and treating concurrent depression caused by diabetes |
| CN104686728A (en) * | 2015-04-02 | 2015-06-10 | 河南中医学院 | Healthcare tea for prevention and treatment of anxiety disorders |
| CN104686727A (en) * | 2015-04-02 | 2015-06-10 | 河南中医学院 | Blood-glucose reduction and nerve soothing health protection tea |
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| CN104686728A (en) * | 2015-04-02 | 2015-06-10 | 河南中医学院 | Healthcare tea for prevention and treatment of anxiety disorders |
| CN104686727A (en) * | 2015-04-02 | 2015-06-10 | 河南中医学院 | Blood-glucose reduction and nerve soothing health protection tea |
| CN104686727B (en) * | 2015-04-02 | 2018-05-25 | 河南中医学院 | A kind of hypoglycemic is soothed the spirit health protection tea |
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