CN104306525A - Traditional Chinese medicine preparation for treating neurasthenia - Google Patents

Traditional Chinese medicine preparation for treating neurasthenia Download PDF

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CN104306525A
CN104306525A CN201410572600.5A CN201410572600A CN104306525A CN 104306525 A CN104306525 A CN 104306525A CN 201410572600 A CN201410572600 A CN 201410572600A CN 104306525 A CN104306525 A CN 104306525A
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fructus
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radix
chinese medicine
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张益玲
杨明娟
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating neurasthenia. The preparation is prepared from the following medicinal raw materials by weight: 30-50g of alcohol processed radix angelica sinensis, 20-30g of radix paeoniae alba, 10-20g of poria cocos, 10-20g of hairyvein agrimony, 10-20g of schisandra chinensis, 10-20g of polygala tenuifolia, 10-20g of cinnamon, 10-20g of donkey-hide gelatin, 10-20g of pawpaw, 8-15g of rhizoma nardostachyos, 8-12g of concha haliotidis, 8-12g of uncaria, 8-12g of loofah sponge, 8-12g of glossy privet fruit, 8-12g of cape jasmine and 8-12g of longan pulp. The medicinal raw materials are well combined to play effects of tonifying qi, nourishing blood, nourishing heart and tranquilizing, and the traditional Chinese medicine preparation has a remarkable effect and exact curative effect on treatment of neurasthenia, cannot easily form addiction or dependence, is safe and reliable, and is worthy of clinical popularization and application.

Description

One treats neurasthenic Chinese medicine preparation
Technical field
The invention belongs to the field of Chinese medicines, one can treat neurasthenic Chinese medicine preparation specifically.
Background technology
The commonly encountered diseases of neurasthenia's to be common be department of neurology, be a class spirit easily excited and mental easily tired, to be often in a bad mood the neurosis disorder of worry and psychology physiological symptom.The neurasthenic symptom of handlebar is confined to the easily tired tendency for main manifestations in the world.Between twenty and fifty phase morbidity is more, and mental worker is more common.Account for the more than half of outpatient clinic Patients with Neurosis.
Neurasthenic generation is mostly with nervous relevant with stress for a long time, and women's prevalence is apparently higher than male, and more than between twenty and fifty onset, clinical main manifestations is insomnia, dreaminess, forgetful, fatigue and weak, dizziness, tinnitus etc.Main based on psychotherapy and Drug therapy at present in treatment, drug main will comprise anxiety, sedative hypnotic and tricyclics, but these medicines all have obvious side effect, patient is easily made to produce drug dependence, cure the symptoms, not the disease, long-term taking, the physical and mental health of serious harm patient.
Summary of the invention
The invention solves the defect and deficiency that exist in treatment neurasthenia at present, provide a kind of Be very effective, determined curative effect, the Chinese medicine preparation that has no side effect.
The technical solution adopted in the present invention is: one treats neurasthenic Chinese medicine preparation, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis (processed with wine) 30-50 gram, Radix Paeoniae Alba 20-30 gram, Poria 10-20 gram, Herba Agrimoniae 10-20 gram, Fructus Schisandrae Chinensis 10-20 gram, Radix Polygalae 10-20 gram, Cortex Cinnamomi 10-20 gram, Colla Corii Asini 10-20 gram, Fructus Chaenomelis 10-20 gram, Radix Et Rhizoma Nardostachyos 8-15 gram, Concha Haliotidis 8-12 gram, Ramulus Uncariae Cum Uncis 8-12 gram, Retinervus Luffae Fructus 8-12 gram, Fructus Ligustri Lucidi 8-12 gram, Fructus Gardeniae 8-12 gram, Arillus Longan 8-12 gram.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis (processed with wine) 30 grams, the Radix Paeoniae Alba 20 grams, 10 grams, Poria, Herba Agrimoniae 10 grams, Fructus Schisandrae Chinensis 10 grams, Radix Polygalae 10 grams, Cortex Cinnamomi 10 grams, 10 grams, Colla Corii Asini, Fructus Chaenomelis 10 grams, Radix Et Rhizoma Nardostachyos 8 grams, Concha Haliotidis 8 grams, Ramulus Uncariae Cum Uncis 8 grams, Retinervus Luffae Fructus 8 grams, Fructus Ligustri Lucidi 8 grams, Fructus Gardeniae 8 grams, Arillus Longan 8 grams.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis (processed with wine) 40 grams, the Radix Paeoniae Alba 25 grams, 15 grams, Poria, Herba Agrimoniae 15 grams, Fructus Schisandrae Chinensis 15 grams, Radix Polygalae 15 grams, Cortex Cinnamomi 15 grams, 15 grams, Colla Corii Asini, Fructus Chaenomelis 15 grams, Radix Et Rhizoma Nardostachyos 12 grams, Concha Haliotidis 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Retinervus Luffae Fructus 10 grams, Fructus Ligustri Lucidi 10 grams, Fructus Gardeniae 10 grams, Arillus Longan 10 grams.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis (processed with wine) 50 grams, the Radix Paeoniae Alba 30 grams, 20 grams, Poria, Herba Agrimoniae 20 grams, Fructus Schisandrae Chinensis 20 grams, Radix Polygalae 20 grams, Cortex Cinnamomi 20 grams, 20 grams, Colla Corii Asini, Fructus Chaenomelis 20 grams, Radix Et Rhizoma Nardostachyos 15 grams, Concha Haliotidis 12 grams, Ramulus Uncariae Cum Uncis 12 grams, Retinervus Luffae Fructus 12 grams, Fructus Ligustri Lucidi 12 grams, Fructus Gardeniae 12 grams, Arillus Longan 12 grams.
The instructions of taking of above-mentioned Chinese medicine preparation is: after being mixed by the Chinese herb of above-mentioned weight proportion, traditionally the method for fried Chinese medicine gets its medicine juice, every day 1 dose, and point 2 clothes, surrounding is a course for the treatment of.
The raw material Chinese medicine of above-mentioned Chinese medicine preparation:
Radix Angelicae Sinensis (processed with wine), sweet in the mouth, pungent, warm in nature; GUIXIN, liver, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.
The Radix Paeoniae Alba, bitter in the mouth, acid, cold nature; Return Liver Channel.There is the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, effect of suppressing the hyperactive liver and subsiding YANG.
Poria, sweet in the mouth, light, property are put down; Enter the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.
Herba Agrimoniae, bitter in the mouth, puckery, property is put down; Return lung, liver, spleen channel.There is astringing to arrest bleeding, effect of antibacterial dysentery relieving.
Fructus Schisandrae Chinensis, sour in the mouth, warm in nature; Return lung, kidney, heart channel.Have nourishing kidney of astringing the lung, promote the production of body fluid arresting sweating, effect of arresting seminal emission antidiarrheal.
Radix Polygalae, acrid in the mouth, hardship, warm in nature; GUIXIN, kidney, lung meridian.There is waking up the patient from unconsciousness by clearing away phlegm, the effect of Fructus Alpiniae Oxyphyllae of calming the nerves.
Cortex Cinnamomi, acrid in the mouth, sweet, hot in nature.Return kidney, spleen, the heart, Liver Channel.There is benefit fire supporing yang, dispersing cold for relieving pain, effect of promoting the flow of QI-blood by warming the meridian.
Colla Corii Asini, sweet in the mouth, property is put down; Return lung, the heart, liver, kidney channel.To asthenia anemia, pulmonary fistula is spat blood, and tire produces the diseases such as metrorrhagia good treatment, is tonifying blood and arresting bleeding, nourshing Yin and drynsessmoistening prescription good medicine.
Fructus Chaenomelis, warm in nature, sour in the mouth; Return liver, spleen channel.There is relaxing muscles and tendons and activating QI and blood in the collateral, effect of removing dampness to restore normal function of the stomach.
Radix Et Rhizoma Nardostachyos, taste acrid, sweet, warm; Return spleen, stomach warp.There are promoting the circulation of QI to relieve pain, effect of relieving stagnation and activating the spleen.
Concha Haliotidis, bitter in the mouth, sweet, salty, cold nature; Enter liver, kidney, large intestine channel.Having loosening bowel to relieve constipation, effect of blood fat reducing improving eyesight, is the key medicine of Liang Gan town liver.
Ramulus Uncariae Cum Uncis, cold in nature, sweet in the mouth; Return liver, gallbladder, pericardium channel.There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.Be used for heat clearing away suppressing the hyperactive liver, spasmolytic relieves dizziness, high fever, infantile convulsions, epilepsy, etc.
Retinervus Luffae Fructus, sweet in the mouth, property are flat, return lung, stomach, Liver Channel.There is dredge the meridian passage, removing heat-phlegm, removing toxic substances and promoting subsidence of swelling, effect of heart tonifying diuresis.
Fructus Ligustri Lucidi, property is flat, sweet in the mouth; Return liver, kidney channel.There is the kidney invigorating nourishing the liver, replenishing vital essence to improve eyesight, effect of heat-clearing and toxic substances removing.
Fructus Gardeniae, bitter in the mouth, cold in nature; Return lung, kidney, the heart, liver, tri-jiao channel.There is pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, effect of reducing swelling and alleviating pain.
Arillus Longan, sweet in the mouth, warm in nature; GUIXIN, spleen channel.There is invigorating the heart and spleen, benefiting QI and nourishing blood, effect of feeling at ease of allaying excitement.
Neurasthenia belongs to the category such as " strongly fragrant disease ", " insomnia ", " asthenia ", " cardiopalmus " of the traditional Chinese medical science, mainly excessively causes mechanism of qi obstruction, transporting and transforming function of the spleen and stomach unable by working with one's mind, so that insufficiency of vital energy and blood, cannot calm the nerves caused by nourishing heart.In Chinese medicine preparation of the present invention, Radix Angelicae Sinensis (processed with wine), Ramulus Uncariae Cum Uncis, the Radix Paeoniae Alba, Concha Haliotidis can blood-activating and qi-promoting, and nourish blood yin fluid astringing, heat clearing away suppressing the hyperactive liver; Arillus Longan, Colla Corii Asini, Fructus Ligustri Lucidi can soothing livers and strengthening spleens, and benefiting QI and nourishing blood, allays excitement and feel at ease; Poria, Fructus Chaenomelis, Radix Et Rhizoma Nardostachyos, Radix Polygalae can invigorating the spleen and regulating the stomach, circulation of qi promoting removing dampness, Fructus Alpiniae Oxyphyllae of calming the nerves; Herba Agrimoniae, Fructus Schisandrae Chinensis, Cortex Cinnamomi can be astringed the lung nourishing kidney, promote the production of body fluid and hold back blood, promoting the flow of QI-blood by warming the meridian; Retinervus Luffae Fructus, Fructus Gardeniae can pathogenic fire purging relieving restlessness, removing toxic substances and promoting subsidence of swelling, removing heat-phlegm.All medicines coordinate, altogether long memorial liver spleen, and vigorate qi and replenish the blood, tranquilizing by nourishing the heart, effect that relieving restlessness is calmed the nerves, effectively can improve microcirculation in human body, rapid allaying tiredness, refreshes, improving water flood quality.This medicine is used for the treatment of neurasthenia and has good curative effect, and this medicine makes easily in addition, cheap, and has no side effect and drug dependence, clinic promotion and application.
For investigating the clinical efficacy of medicine of the present invention further, we have selected 98 routine out-patients and carry out clinical trial, and patient is mostly brain worker, and cardinal symptom is insomnia, brain is not enough, anxious state of mind is large, does not take in the past to treat.All patients are divided into 2 groups at random, treatment group 49 example, man 18 example, female 31 example, age 22-65 year, average 43 years old; The shortest person of the course of disease 3 months, most elder 3 years.Matched group 49 example, man 20 example, female 29 example, age 20-63 year, average 42 years old; The shortest person of the course of disease 2.5 months, most elder 3.5 years.The equal not statistically significants of difference (P > 0.05) such as two groups of case sexes, age, occupation, the course of disease, state of an illness, have comparability.
Therapeutic Method:
Treatment group takes Chinese medicine preparation of the present invention, and concrete grammar is that traditionally the method for fried Chinese medicine gets its medicine juice, every day 1 dose by after above-mentioned raw material of Chinese medicine mixing, and point 2 clothes ten days are a course for the treatment of.Matched group takes the existing ANSHEN BUNAO YE in market (Jilin Aodong Yanbian Medicine Industry Co., Ltd produce, lot number 20050811), each 1 (10mL), every day sooner or later 2 times oral.Two groups 4 weeks is all 1 course for the treatment of in treatment, and treatments period does not take other any medicines.
Observation index and scoring:
Treatments period, to 2 groups of patients all in the 7th, 14,21,28 daily inspections scorings, the symptom variation such as main detection insomnia, dreaminess, forgetful, fatigue and weak, dizziness, tinnitus, standards of grading are, asymptomatic or transference cure person: 0 point; Symptom is slight person 1 point; Symptom moderate person: 2 points; Symptom severe person: 3 points.
Criterion of therapeutical effect:
Cure: clinical symptoms disappears completely, and symptom integral is 0 point;
Effective: clinical cardinal symptom disappears completely, symptom integral reduces > 2/3;
Effective: clinical cardinal symptom makes moderate progress, symptom integral reduces > 1/3;
Invalid: symptom is without improvement, and integration reduces < 1/3 or increases to some extent.
Therapeutic outcome:
1, clinical efficacy result
After two groups of treatments, treatment group cures 12 examples, effective 18 examples, effective 15 examples, invalid 4 examples, total effective rate 91.8%; Matched group cures 4 examples, effective 19 examples, effective 17 examples, no effect 9, total effective rate 81.6%; Treatment group effective percentage is apparently higher than matched group, and between group, comparing difference is remarkable, has statistical significance (P < 0.05).Detailed results is in table 1.
Table 1: two groups of clinical efficacy Comparative result
Group Number of cases Cure n (%) Effective n (%) Effective n (%) Invalid n (%) Total effective rate (%)
Treatment group 49 12(24.5) 18(36.7) 15(30.6) 4(8.2) 91.8
Matched group 49 4(8.2) 19(38.8) 17(34.7) 9(18.4) 81.6
2, the change of main clinic symptoms integration differential is compared
Index according to the observation, integration judgement is carried out to cardinal symptoms such as insomnia, dreaminess, forgetful, fatigue and weak, dizziness, tinnitus, treatment group integration is obviously better than matched group, and between group, comparing difference is remarkable, has statistical significance (P < 0.05).Detailed results is in table 2.
Table 2: clinical cardinal symptom integration differential change is compared
3. side effect is compared:
In safety observations result observation process, two groups of patients all do not find obvious adverse reaction.Detect without special change before and after the conventional and electrocardiogram of primary safety index blood, urine, feces, ALT, BUN, SCr treatment.
Result shows, Chinese medicine preparation treatment neurasthenia instant effect of the present invention, short treating period, determined curative effect, effectively can eliminate insomnia that neurasthenia causes, daydream, many symptoms such as forgetful simultaneously, and in therapeutic process, do not find obvious side effect and adverse effect, not easily form drug addiction and dependency, safe and reliable, clinic promotion and application.
Detailed description of the invention
Embodiment 1: one treats neurasthenic Chinese medicine preparation, chooses Radix Angelicae Sinensis (processed with wine) 30 grams, the Radix Paeoniae Alba 20 grams, 10 grams, Poria, Herba Agrimoniae 10 grams, Fructus Schisandrae Chinensis 10 grams, Radix Polygalae 10 grams, Cortex Cinnamomi 10 grams, 10 grams, Colla Corii Asini, Fructus Chaenomelis 10 grams, Radix Et Rhizoma Nardostachyos 8 grams, Concha Haliotidis 8 grams, Ramulus Uncariae Cum Uncis 8 grams, Retinervus Luffae Fructus 8 grams, Fructus Ligustri Lucidi 8 grams, Fructus Gardeniae 8 grams, Arillus Longan 8 grams.
Embodiment 2: one treats neurasthenic Chinese medicine preparation, chooses Radix Angelicae Sinensis (processed with wine) 40 grams, the Radix Paeoniae Alba 25 grams, 15 grams, Poria, Herba Agrimoniae 15 grams, Fructus Schisandrae Chinensis 15 grams, Radix Polygalae 15 grams, Cortex Cinnamomi 15 grams, 15 grams, Colla Corii Asini, Fructus Chaenomelis 15 grams, Radix Et Rhizoma Nardostachyos 12 grams, Concha Haliotidis 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Retinervus Luffae Fructus 10 grams, Fructus Ligustri Lucidi 10 grams, Fructus Gardeniae 10 grams, Arillus Longan 10 grams.
Embodiment 3: one treats neurasthenic Chinese medicine preparation, chooses Radix Angelicae Sinensis (processed with wine) 50 grams, the Radix Paeoniae Alba 30 grams, 20 grams, Poria, Herba Agrimoniae 20 grams, Fructus Schisandrae Chinensis 20 grams, Radix Polygalae 20 grams, Cortex Cinnamomi 20 grams, 20 grams, Colla Corii Asini, Fructus Chaenomelis 20 grams, Radix Et Rhizoma Nardostachyos 15 grams, Concha Haliotidis 12 grams, Ramulus Uncariae Cum Uncis 12 grams, Retinervus Luffae Fructus 12 grams, Fructus Ligustri Lucidi 12 grams, Fructus Gardeniae 12 grams, Arillus Longan 12 grams.
Below by concrete case, Chinese medicine preparation curative effect of the present invention is verified further:
Case 1
Zhao's ××, female, 39 years old.Often there is feel not sleep well in evening in patient, insomnia, dreaminess the year before, and every day improves spirit by vitimin supplement, covers up black eye and tired out, after half a year, because portfolio increases, work overtime continuously, cause the symptom of deficiency of heart-QI to deepen by cosmetic.Health is especially easily tired, obviously feels that I is not enough, and anxious state of mind is large, and easily flighty and impetuous, through detecting in detail, diagnosis leaf patient is moderate neurasthenia.Upon somebody's introduction, take Chinese medicine preparation of the present invention, about 3 weeks, patient's somatization disappears substantially, and insomnia takes a turn for the better, and neurasthenia also obviously alleviates.Continue to take medicine in addition after treatment in 1 week, and patient returns to one's perfect health, and sleep is normal, is emotionally stable, spirit and QI cleaning.Follow up a case by regular visits to 3 moonsets after drug withdrawal to recur again.
Case 2
King's ××, female, 45 years old.The situation of having a sleepless night was there is in patient before 2 years, start just difficulty falling asleep, nighttime sleep is of poor quality, patient does not take notice of, think that work strain, pressure cause greatly in the past few days, develop into afterwards and lie awake all night, or slightly can fall asleep, and with dizzy, uncomfortable in chest, cardiopalmus, the symptom such as weak, have a strong impact on normal work.Hospital's detailed diagnostics is insomnia companion neurasthenia, and after taking western medicine, remission, is difficult to again after drug withdrawal fall asleep, Relapse rate.Rear surprising introduction is taken Chinese medicine preparation of the present invention and is treated, and after taking medicine 2 weeks, patient sleeps improves obviously, and dizzy, uncomfortable in chest, cardiopalmus, the symptom such as weak alleviate; After continuing to take medicine 1 month, all diseases of patient all disappear, and nighttime sleep is good, and complexion recovers normal, clinical cure.Follow up a case by regular visits to and have no recurrence half a year.
Case 3
Du's ××, man, 34 years old.Patient is a secondary school teachers, and over nearly 3 years, due to work strain, task weight, pressure is large, engenders insomnia, shows as difficulty falling asleep, needs two or three hours ability to fall asleep, easily wakes up with a start, dreaminess after sleeping.Daytime is drowsy, and spirit is poor, fatiguability, and upper class hour is absent minded, and memory and the learning efficiency decline, and occurs dizzy headache, and emotion is fidgety.Very low through hospital detailed inspection display patient brain neurotransmitter index, be diagnosed as neurasthenia.Upon somebody's introduction, patient starts to take Chinese medicine preparation of the present invention and treats, and about medication two weeks, patient's readme mental status takes a turn for the better, and somatosensory has vigor, sleeps than easy to some extent in the past; Hold on more than drug administration January, all diseases of patient all disappear, and recover normal, clinical cure.Effect of follow-up visit by telephone has no recurrence in 1 year.

Claims (4)

1. treat a neurasthenic Chinese medicine preparation, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis (processed with wine) 30-50 gram, Radix Paeoniae Alba 20-30 gram, Poria 10-20 gram, Herba Agrimoniae 10-20 gram, Fructus Schisandrae Chinensis 10-20 gram, Radix Polygalae 10-20 gram, Cortex Cinnamomi 10-20 gram, Colla Corii Asini 10-20 gram, Fructus Chaenomelis 10-20 gram, Radix Et Rhizoma Nardostachyos 8-15 gram, Concha Haliotidis 8-12 gram, Ramulus Uncariae Cum Uncis 8-12 gram, Retinervus Luffae Fructus 8-12 gram, Fructus Ligustri Lucidi 8-12 gram, Fructus Gardeniae 8-12 gram, Arillus Longan 8-12 gram.
2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation comprises the Chinese herb of following weight in grams:
Radix Angelicae Sinensis (processed with wine) 30 grams, the Radix Paeoniae Alba 20 grams, 10 grams, Poria, Herba Agrimoniae 10 grams, Fructus Schisandrae Chinensis 10 grams, Radix Polygalae 10 grams, Cortex Cinnamomi 10 grams, 10 grams, Colla Corii Asini, Fructus Chaenomelis 10 grams, Radix Et Rhizoma Nardostachyos 8 grams, Concha Haliotidis 8 grams, Ramulus Uncariae Cum Uncis 8 grams, Retinervus Luffae Fructus 8 grams, Fructus Ligustri Lucidi 8 grams, Fructus Gardeniae 8 grams, Arillus Longan 8 grams.
3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation comprises the Chinese herb of following weight in grams:
Radix Angelicae Sinensis (processed with wine) 40 grams, the Radix Paeoniae Alba 25 grams, 15 grams, Poria, Herba Agrimoniae 15 grams, Fructus Schisandrae Chinensis 15 grams, Radix Polygalae 15 grams, Cortex Cinnamomi 15 grams, 15 grams, Colla Corii Asini, Fructus Chaenomelis 15 grams, Radix Et Rhizoma Nardostachyos 12 grams, Concha Haliotidis 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Retinervus Luffae Fructus 10 grams, Fructus Ligustri Lucidi 10 grams, Fructus Gardeniae 10 grams, Arillus Longan 10 grams.
4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation comprises the Chinese herb of following weight in grams:
Radix Angelicae Sinensis (processed with wine) 50 grams, the Radix Paeoniae Alba 30 grams, 20 grams, Poria, Herba Agrimoniae 20 grams, Fructus Schisandrae Chinensis 20 grams, Radix Polygalae 20 grams, Cortex Cinnamomi 20 grams, 20 grams, Colla Corii Asini, Fructus Chaenomelis 20 grams, Radix Et Rhizoma Nardostachyos 15 grams, Concha Haliotidis 12 grams, Ramulus Uncariae Cum Uncis 12 grams, Retinervus Luffae Fructus 12 grams, Fructus Ligustri Lucidi 12 grams, Fructus Gardeniae 12 grams, Arillus Longan 12 grams.
CN201410572600.5A 2014-10-23 2014-10-23 Traditional Chinese medicine preparation for treating neurasthenia Pending CN104306525A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1121811A (en) * 1994-05-12 1996-05-08 广东医学院医药科技开发中心 Drug prescription for treatment of neurosis and preparing method thereof
CN1686496A (en) * 2005-04-13 2005-10-26 蒋希民 Medicine for treating neurasthenia and its preparation method
CN102078559A (en) * 2009-12-01 2011-06-01 王小华 Chinese medicinal composition with functions of tonifying kidney and strengthening brain
CN103110915A (en) * 2013-01-17 2013-05-22 栾雷 Traditional Chinese medical composition for treating neurasthenia

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1121811A (en) * 1994-05-12 1996-05-08 广东医学院医药科技开发中心 Drug prescription for treatment of neurosis and preparing method thereof
CN1686496A (en) * 2005-04-13 2005-10-26 蒋希民 Medicine for treating neurasthenia and its preparation method
CN102078559A (en) * 2009-12-01 2011-06-01 王小华 Chinese medicinal composition with functions of tonifying kidney and strengthening brain
CN103110915A (en) * 2013-01-17 2013-05-22 栾雷 Traditional Chinese medical composition for treating neurasthenia

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
苏金奎: "神经衰弱的中医辩证治", 《河南中医药学刊》 *

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Application publication date: 20150128