CN104288495A - Chinese yam-rhizoma polygonati capsule and preparation method thereof - Google Patents

Chinese yam-rhizoma polygonati capsule and preparation method thereof Download PDF

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CN104288495A
CN104288495A CN201410486433.2A CN201410486433A CN104288495A CN 104288495 A CN104288495 A CN 104288495A CN 201410486433 A CN201410486433 A CN 201410486433A CN 104288495 A CN104288495 A CN 104288495A
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capsule
rhizoma polygonati
parts
angelicae sinensis
rhizoma
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陈宝香
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MENGZHOU EXPO BIOTECHNOLOGY CO Ltd
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MENGZHOU EXPO BIOTECHNOLOGY CO Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention relates to a Chinese yam-rhizoma polygonati capsule and a preparation method thereof. The Chinese yam-rhizoma polygonati capsule is prepared from the following components in parts by weight: 5800-6200 parts of Chinese yam, 800-1200 parts of ginseng, 2800-3200 parts of Chinese angelica, 2800-3200 parts of fruits of wolfberry, 2800-3200 parts of rhizoma polygonati and 2800-3200 parts of poria cocos. The Chinese yam-rhizoma polygonati capsule disclosed by the invention is prepared from the Chinese yam, the ginseng, the Chinese angelica, the wolfberry, the rhizoma polygonati and the poria cocos according to a fixed proportion and are natural plant raw materials, any additive is not added, the raw material proportion is simple and reasonable, and the effects of the raw materials supplement each other, so that the effective ingredients of the Chinese yam, the ginseng, the Chinese angelica, the wolfberry, the rhizoma polygonati and the poria cocos are kept very well, and thus, the Chinese yam-rhizoma polygonati capsule has the effects of tonifying spleen nourishing the stomach, promoting the secretion of saliva or body fluid to benefit lungs, reinforcing vital energy, restoring the pulses for relieving desertion, enriching the blood and activating the blood, regulating menstruation to relieve pain, relaxing bowels, nourishing livers and kidneys, replenishing vital essence to improve eyesight, tonifying spleen, detoxifying, dehumidifying and easing joint movement.

Description

A kind of Rhizoma Dioscoreae Rhizoma Polygonati capsule and preparation method thereof
Technical field
The invention belongs to pharmaceutical technology sectors, be specifically related to a kind of capsule, particularly relate to a kind of Rhizoma Dioscoreae Rhizoma Polygonati capsule and preparation method thereof.
Background technology
Along with the quickening of work rhythm, there is the phenomenons such as immunity degradation, insomnia and dreamful sleep, irritable in increasing people, affects the live and work of people.China is the country of an aging, this phenomenon of old people is given prominence to, due to modern society, social competition is increasing, high-pressure, highly busy brain physical work damage very large to the body and mind of people and vital functions, the mental pressure particularly therefore caused, social pressure, family's pressure, make the psychology of people, body overload operation, cause the generation of multiple subhealth state, sub-ill phenomenon, this phenomenon tends to rejuvenation gradually, therefore needs a kind of health product improving immunity and taking convenience.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art and provide a kind of by natural material make there is spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, strongly invigorating primordial QI, multiple arteries and veins take off admittedly, enrich blood invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation, nourishing the liver and kidney, replenishing vital essence to improve eyesight, spleen invigorating effect, removing toxic substances, dehumidifying, easing joint movement effect Rhizoma Dioscoreae Rhizoma Polygonati capsule.
Technical solution of the present invention is: a kind of Rhizoma Dioscoreae Rhizoma Polygonati capsule, it is made up according to following weight proportion of each component: it is made up according to following weight proportion of each component: Rhizoma Dioscoreae 5800-6200 part, Radix Ginseng 800-1200 part, Radix Angelicae Sinensis 2800-3200 part, Fructus Lycii 2800-3200 part, Rhizoma Polygonati 2800-3200 part, Poria 2800-3200 part.
Described a kind of Rhizoma Dioscoreae Rhizoma Polygonati capsule, it is made up according to following weight proportion of each component: it is made up according to following weight proportion of each component: Rhizoma Dioscoreae 6000 parts, Radix Ginseng 1000 parts, Radix Angelicae Sinensis 3000 parts, Fructus Lycii 3000 parts, Rhizoma Polygonati 3000 parts, 3000 parts, Poria.
The preparation method of described Rhizoma Dioscoreae Rhizoma Polygonati capsule, comprises the steps:
Step 1: sterilization: the Radix Angelicae Sinensis Co60 radiation sterilizing getting the Radix Ginseng of recipe quantity and 2/3rds of recipe quantity respectively;
Step 2: dry: the medical material after step 1 being sterilized dries;
Step 3: pulverize: dried for step 2 medical material is carried out pulverization process, and powder particle diameter is not more than 120 orders;
Step 4: draw materials: get respectively the Rhizoma Dioscoreae of recipe quantity, Fructus Lycii, Rhizoma Polygonati, Poria and recipe quantity 1/3rd Radix Angelicae Sinensis put into extract and fill with;
Step 5: warm macerating again: add in the mixture that step 4 is obtained be step 4 draw materials gross mass 8 times pure water after in 40 DEG C ~ 50 DEG C warm macerating 1 hour;
Step 6: first time heats decoction: by the mixture heating decoction after step 5 warm macerating 2 hours;
Step 7: filter: the 100 order stainless (steel) wires of the mixture after step 6 being decocted filter, obtains first time filtrate;
Step 8: second time heats decoction: adding in the medicinal residues after step 6 being filtered is that the draw materials pure water post-heating of gross mass 6 times of step 4 decocts 1.5 hours;
Step 9: refilter: the 100 order stainless (steel) wires of the mixture after step 8 being decocted filter, obtains second time filtrate;
Step 10: merge: first time filtrate is combined with second time filtrate;
Step 11: concentrated: the liquid after merging puts into decompression concentrator, and reduced pressure atmosphere is: vacuum 0.06-0.08MPa, and temperature is 80 DEG C, adding hot filtrate, to be concentrated into relative density be 1.15 ~ 1.25;
Step 12: mixing: get Radix Ginseng that step 3 obtains and Radix Angelicae Sinensis fine powder and add mixing granulation in concentrated solution that step 11 obtains, every weight is 0.4g;
Step 13: dry: granule step 12 obtained is dried in 60-80 DEG C of environment, and ensure moisture content≤5%;
Step 14: capsule shells filling: the granule of step 13 drying and processing is utilized Autocapsulefillingmachine, is filled into obtained capsule in capsule shells;
Step 15: polishing inspection: capsule shells is carried out polishing inspection, obtains outer wall gloss, without bur;
Step 16: outer package: capsule step 15 obtained utilizes full-automatic overwrapping machine and full-automatic label sticking machine to carry out outer package;
Step 17: warehouse-in: packaged for step 16 capsule is put into warehouse.
The present invention has the following advantages: the present invention is by Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, the Rhizoma Dioscoreae Rhizoma Polygonati capsule that Rhizoma Polygonati and Poria are made according to fixed weight proportioning, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are natural material, proportioning raw materials advantages of simple, effect of each raw material complements each other, it is good health care medicine, Rhizoma Dioscoreae is nutritious because of it, just be regarded as inexpensive tonify deficiency good merchantable brand since ancient times, both staple food grain can be made, vegetable can be done again, adhesive component in RHIIZOMA DIOSCOREAE fr0m Henan of China is made up of the complex of mucoprotein this sugar and protein, mucoprotein have the effect activating androgen, RHIIZOMA DIOSCOREAE fr0m Henan of China has strengthening the spleen and tonifying the lung in a word, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will is calmed the nerves, effect of life lengthening, for weakness of the spleen and stomach, diet reduces, suffer from diarrhoea in loose stool, women's lukorrhagia due to hypofunction of the spleen, chronic cough of deficiency lung dry pharynx, emission due to deficiency of the kidney, Fructus Lycii cures mainly nourishing the liver and kidney, replenishing vital essence to improve eyesight, for asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is failed to understand, containing 14 seed amino acids in Fructus Lycii, and containing special dietary compositions such as betanin, beautiful another name for Sichuan Province flavin, physalins, make it have outstanding health-care effect, Fructus Lycii contains the required nutrient substance of abundant carotene, multivitamin and the healthy eye such as calcium, ferrum, therefore has the merit of improving eyesight, is commonly called as " bright eye ", the superfine product that Radix Ginseng is described as from ancient times " king of BAICAO " " YIN nourishing is mended raw, strengthening the body resistance ", containing multiple Saponin and polysaccharide composition, leachate slowly can be absorbed by skin and without pessimal stimulation, energy skin expansion blood capillary, promotes cutaneous circulation, increase skin-nourishing, the water oil balance of regulation of skin, prevents skin dehydration, sclerosis, wrinkling, the reducing property of Radix Ginseng active substance check melanin, make skin pure white smooth, can strengthen skin elasticity, cell be obtained newborn, be the superfine product of improving looks, Radix Angelicae Sinensis can be enriched blood, and can invigorate blood circulation again, is referred to as and blood, has to enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, Rhizoma Polygonati has benefit vital essence, controls weakness of the spleen and stomach, fatigue and lack of strength, strengthening bone and muscle, effect of beneficial marrow, Poria is containing pachyman, glucose, protein, aminoacid, organic acid, fat, lecithin, adenine, choline, ergosterol, multiple enzyme and potassium salt, energy enhancing human body immunity function, pachyman has obvious antitumor action, there is diuresis, the electrolytical discharge such as potassium, sodium, chlorine in urine can be increased, have the effect such as generation, blood sugar lowering, anti-radiation of calmness and the liver protecting, suppression ulcer, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are made capsule according to fixed weight proportioning by the present invention, there is drug effect, good health promoting product, for people provide convenience, the present invention has spleen reinforcing nourishing the stomach in a word, the lung benefiting that promotes the production of body fluid, strongly invigorating primordial QI, multiple arteries and veins take off admittedly, enrich blood invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation, nourishing the liver and kidney, replenishing vital essence to improve eyesight, spleen invigorating effect, removing toxic substances, dehumidifying, easing joint movement effect.
The pharmacological property of RHIIZOMA DIOSCOREAE fr0m Henan of China of the present invention, Fructus Lycii, Radix Ginseng, Radix Angelicae Sinensis, Rhizoma Polygonati, Poria is analyzed as follows:
1) RHIIZOMA DIOSCOREAE fr0m Henan of China: herbaceos perennial, stem is overgrow, and is often with purple, and tuber is cylindrical, and leaf is to life, avette or oval, flower milky, dioecism.
Nature and flavor with return through: sweet, flat; Return spleen, lung, kidney channel.
Function cures mainly: insufficiency of the spleen lack of appetite, incessant chronic diarrhea, and the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.
2) Fructus Lycii: be the mature fruit of matrimony vine of solanaceae plant.
Nature and flavor with return through: sweet, flat; Return liver, kidney channel.
Function cures mainly: asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, impotence and seminal emission, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
3) Radix Ginseng: be herbaceos perennial, happiness is shady and cool, and blade pore-free and palisade tissue, cannot retain moisture, and temperature can be burnt higher than 32 degree of blades, canopy density 0.7-0.8.Within usual 3 years, bloom, 5-6 annual bearing, the florescence 5-6 month, the fruit phase 6-9 month.
Nature and flavor with return through sweet, micro-hardship, tepor; Return spleen, lung, the heart, kidney channel.
Function cures mainly: weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, and the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, deficiency of qi and blood, prolonged illness weakness with emaciation, palpitation with fear insomnia, sexual impotence cold womb.
4) Radix Angelicae Sinensis: herbaceos perennial.
Nature and flavor with return through: sweet, pungent, warm; Return liver, the heart, spleen channel.
Function cures mainly: blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
5) Rhizoma Polygonati: HUANGJING ZANYU CAPSULE, rhizome horizontal walk, cylindric, tuberosity expands.Impeller is raw, stockless.
Nature and flavor with return through: sweet, flat; Return spleen, lung, kidney channel.
Function cures mainly: deficiency of spleen-QI and stomach-QI, fatigue and asthenia, deficiency of stomach-Yin, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, chronic cough hemoptysis, asthenia of essence and blood, soreness of the waist and knees, and early whitening of beard and hair, interior-heat is quenched one's thirst.
6) Poria: medicinal part is the sclerotium of On Polyporaceae Poria.
Nature and flavor with return through: sweet, light, flat; Return liver, stomach warp.
Function cures mainly: syphilis and the limbs contracture caused by mercurialism, bones and muscles pain; Damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1
A kind of Rhizoma Dioscoreae Rhizoma Polygonati capsule, it is made up according to following weight proportion of each component: it is made up according to following weight proportion of each component: Rhizoma Dioscoreae 5800 parts, Radix Ginseng 800 parts, Radix Angelicae Sinensis 2800 parts, Fructus Lycii 2800 parts, Rhizoma Polygonati 2800 parts, 2800 parts, Poria.
The preparation method of described Rhizoma Dioscoreae Rhizoma Polygonati capsule, comprises the steps:
Step 1: sterilization: the Radix Angelicae Sinensis Co60 radiation sterilizing getting the Radix Ginseng of recipe quantity and 2/3rds of recipe quantity respectively;
Step 2: dry: the medical material after step 1 being sterilized dries;
Step 3: pulverize: dried for step 2 medical material is carried out pulverization process, and powder particle diameter is not more than 120 orders;
Step 4: draw materials: get respectively the Rhizoma Dioscoreae of recipe quantity, Fructus Lycii, Rhizoma Polygonati, Poria and recipe quantity 1/3rd Radix Angelicae Sinensis put into extract and fill with;
Step 5: warm macerating again: add in the mixture that step 4 is obtained be step 4 draw materials gross mass 8 times pure water after in 40 DEG C ~ 50 DEG C warm macerating 1 hour;
Step 6: first time heats decoction: by the mixture heating decoction after step 5 warm macerating 2 hours;
Step 7: filter: the 100 order stainless (steel) wires of the mixture after step 6 being decocted filter, obtains first time filtrate;
Step 8: second time heats decoction: adding in the medicinal residues after step 6 being filtered is that the draw materials pure water post-heating of gross mass 6 times of step 4 decocts 1.5 hours;
Step 9: refilter: the 100 order stainless (steel) wires of the mixture after step 8 being decocted filter, obtains second time filtrate;
Step 10: merge: first time filtrate is combined with second time filtrate;
Step 11: concentrated: the liquid after merging puts into decompression concentrator, and reduced pressure atmosphere is: vacuum 0.06-0.08MPa, and temperature is 80 DEG C, adding hot filtrate, to be concentrated into relative density be 1.15 ~ 1.25;
Step 12: mixing: get Radix Ginseng that step 3 obtains and Radix Angelicae Sinensis fine powder and add mixing granulation in concentrated solution that step 11 obtains, every weight is 0.4g;
Step 13: dry: granule step 12 obtained is dried in 60-80 DEG C of environment, and ensure moisture content≤5%;
Step 14: capsule shells filling: the granule of step 13 drying and processing is utilized Autocapsulefillingmachine, is filled into obtained capsule in capsule shells;
Step 15: polishing inspection: capsule shells is carried out polishing inspection, obtains outer wall gloss, without bur;
Step 16: outer package: capsule step 15 obtained utilizes full-automatic overwrapping machine and full-automatic label sticking machine to carry out outer package;
Step 17: warehouse-in: packaged for step 16 capsule is put into warehouse.
The present invention has the following advantages: the present invention is by Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, the Rhizoma Dioscoreae Rhizoma Polygonati capsule that Rhizoma Polygonati and Poria are made according to fixed weight proportioning, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are natural material, proportioning raw materials advantages of simple, effect of each raw material complements each other, it is good health care medicine, Rhizoma Dioscoreae is nutritious because of it, just be regarded as inexpensive tonify deficiency good merchantable brand since ancient times, both staple food grain can be made, vegetable can be done again, adhesive component in RHIIZOMA DIOSCOREAE fr0m Henan of China is made up of the complex of mucoprotein this sugar and protein, mucoprotein have the effect activating androgen, RHIIZOMA DIOSCOREAE fr0m Henan of China has strengthening the spleen and tonifying the lung in a word, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will is calmed the nerves, effect of life lengthening, for weakness of the spleen and stomach, diet reduces, suffer from diarrhoea in loose stool, women's lukorrhagia due to hypofunction of the spleen, chronic cough of deficiency lung dry pharynx, emission due to deficiency of the kidney, Fructus Lycii cures mainly nourishing the liver and kidney, replenishing vital essence to improve eyesight, for asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is failed to understand, containing 14 seed amino acids in Fructus Lycii, and containing special dietary compositions such as betanin, beautiful another name for Sichuan Province flavin, physalins, make it have outstanding health-care effect, Fructus Lycii contains the required nutrient substance of abundant carotene, multivitamin and the healthy eye such as calcium, ferrum, therefore has the merit of improving eyesight, is commonly called as " bright eye ", the superfine product that Radix Ginseng is described as from ancient times " king of BAICAO " " YIN nourishing is mended raw, strengthening the body resistance ", containing multiple Saponin and polysaccharide composition, leachate slowly can be absorbed by skin and without pessimal stimulation, energy skin expansion blood capillary, promotes cutaneous circulation, increase skin-nourishing, the water oil balance of regulation of skin, prevents skin dehydration, sclerosis, wrinkling, the reducing property of Radix Ginseng active substance check melanin, make skin pure white smooth, can strengthen skin elasticity, cell be obtained newborn, be the superfine product of improving looks, Radix Angelicae Sinensis can be enriched blood, and can invigorate blood circulation again, is referred to as and blood, has to enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, Rhizoma Polygonati has benefit vital essence, controls weakness of the spleen and stomach, fatigue and lack of strength, strengthening bone and muscle, effect of beneficial marrow, Poria is containing pachyman, glucose, protein, aminoacid, organic acid, fat, lecithin, adenine, choline, ergosterol, multiple enzyme and potassium salt, energy enhancing human body immunity function, pachyman has obvious antitumor action, there is diuresis, the electrolytical discharge such as potassium, sodium, chlorine in urine can be increased, have the effect such as generation, blood sugar lowering, anti-radiation of calmness and the liver protecting, suppression ulcer, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are made capsule according to fixed weight proportioning by the present invention, there is drug effect, good health promoting product, for people provide convenience, the present invention has spleen reinforcing nourishing the stomach in a word, the lung benefiting that promotes the production of body fluid, strongly invigorating primordial QI, multiple arteries and veins take off admittedly, enrich blood invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation, nourishing the liver and kidney, replenishing vital essence to improve eyesight, spleen invigorating effect, removing toxic substances, dehumidifying, easing joint movement effect.
Embodiment 2
A kind of Rhizoma Dioscoreae Rhizoma Polygonati capsule, it is made up according to following weight proportion of each component: it is made up according to following weight proportion of each component: Rhizoma Dioscoreae 6000 parts, Radix Ginseng 1000 parts, Radix Angelicae Sinensis 3000 parts, Fructus Lycii 3000 parts, Rhizoma Polygonati 3000 parts, 3000 parts, Poria.
The preparation method of described Rhizoma Dioscoreae Rhizoma Polygonati capsule, comprises the steps:
Step 1: sterilization: the Radix Angelicae Sinensis Co60 radiation sterilizing getting the Radix Ginseng of recipe quantity and 2/3rds of recipe quantity respectively;
Step 2: dry: the medical material after step 1 being sterilized dries;
Step 3: pulverize: dried for step 2 medical material is carried out pulverization process, and powder particle diameter is not more than 120 orders;
Step 4: draw materials: get respectively the Rhizoma Dioscoreae of recipe quantity, Fructus Lycii, Rhizoma Polygonati, Poria and recipe quantity 1/3rd Radix Angelicae Sinensis put into extract and fill with;
Step 5: warm macerating again: add in the mixture that step 4 is obtained be step 4 draw materials gross mass 8 times pure water after in 40 DEG C ~ 50 DEG C warm macerating 1 hour;
Step 6: first time heats decoction: by the mixture heating decoction after step 5 warm macerating 2 hours;
Step 7: filter: the 100 order stainless (steel) wires of the mixture after step 6 being decocted filter, obtains first time filtrate;
Step 8: second time heats decoction: adding in the medicinal residues after step 6 being filtered is that the draw materials pure water post-heating of gross mass 6 times of step 4 decocts 1.5 hours;
Step 9: refilter: the 100 order stainless (steel) wires of the mixture after step 8 being decocted filter, obtains second time filtrate;
Step 10: merge: first time filtrate is combined with second time filtrate;
Step 11: concentrated: the liquid after merging puts into decompression concentrator, and reduced pressure atmosphere is: vacuum 0.06-0.08MPa, and temperature is 80 DEG C, adding hot filtrate, to be concentrated into relative density be 1.15 ~ 1.25;
Step 12: mixing: get Radix Ginseng that step 3 obtains and Radix Angelicae Sinensis fine powder and add mixing granulation in concentrated solution that step 11 obtains, every weight is 0.4g;
Step 13: dry: granule step 12 obtained is dried in 60-80 DEG C of environment, and ensure moisture content≤5%;
Step 14: capsule shells filling: the granule of step 13 drying and processing is utilized Autocapsulefillingmachine, is filled into obtained capsule in capsule shells;
Step 15: polishing inspection: capsule shells is carried out polishing inspection, obtains outer wall gloss, without bur;
Step 16: outer package: capsule step 15 obtained utilizes full-automatic overwrapping machine and full-automatic label sticking machine to carry out outer package;
Step 17: warehouse-in: packaged for step 16 capsule is put into warehouse.
The present invention has the following advantages: the present invention is by Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, the Rhizoma Dioscoreae Rhizoma Polygonati capsule that Rhizoma Polygonati and Poria are made according to fixed weight proportioning, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are natural material, proportioning raw materials advantages of simple, effect of each raw material complements each other, it is good health care medicine, Rhizoma Dioscoreae is nutritious because of it, just be regarded as inexpensive tonify deficiency good merchantable brand since ancient times, both staple food grain can be made, vegetable can be done again, adhesive component in RHIIZOMA DIOSCOREAE fr0m Henan of China is made up of the complex of mucoprotein this sugar and protein, mucoprotein have the effect activating androgen, RHIIZOMA DIOSCOREAE fr0m Henan of China has strengthening the spleen and tonifying the lung in a word, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will is calmed the nerves, effect of life lengthening, for weakness of the spleen and stomach, diet reduces, suffer from diarrhoea in loose stool, women's lukorrhagia due to hypofunction of the spleen, chronic cough of deficiency lung dry pharynx, emission due to deficiency of the kidney, Fructus Lycii cures mainly nourishing the liver and kidney, replenishing vital essence to improve eyesight, for asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is failed to understand, containing 14 seed amino acids in Fructus Lycii, and containing special dietary compositions such as betanin, beautiful another name for Sichuan Province flavin, physalins, make it have outstanding health-care effect, Fructus Lycii contains the required nutrient substance of abundant carotene, multivitamin and the healthy eye such as calcium, ferrum, therefore has the merit of improving eyesight, is commonly called as " bright eye ", the superfine product that Radix Ginseng is described as from ancient times " king of BAICAO " " YIN nourishing is mended raw, strengthening the body resistance ", containing multiple Saponin and polysaccharide composition, leachate slowly can be absorbed by skin and without pessimal stimulation, energy skin expansion blood capillary, promotes cutaneous circulation, increase skin-nourishing, the water oil balance of regulation of skin, prevents skin dehydration, sclerosis, wrinkling, the reducing property of Radix Ginseng active substance check melanin, make skin pure white smooth, can strengthen skin elasticity, cell be obtained newborn, be the superfine product of improving looks, Radix Angelicae Sinensis can be enriched blood, and can invigorate blood circulation again, is referred to as and blood, has to enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, Rhizoma Polygonati has benefit vital essence, controls weakness of the spleen and stomach, fatigue and lack of strength, strengthening bone and muscle, effect of beneficial marrow, Poria is containing pachyman, glucose, protein, aminoacid, organic acid, fat, lecithin, adenine, choline, ergosterol, multiple enzyme and potassium salt, energy enhancing human body immunity function, pachyman has obvious antitumor action, there is diuresis, the electrolytical discharge such as potassium, sodium, chlorine in urine can be increased, have the effect such as generation, blood sugar lowering, anti-radiation of calmness and the liver protecting, suppression ulcer, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are made capsule according to fixed weight proportioning by the present invention, there is drug effect, good health promoting product, for people provide convenience, the present invention has spleen reinforcing nourishing the stomach in a word, the lung benefiting that promotes the production of body fluid, strongly invigorating primordial QI, multiple arteries and veins take off admittedly, enrich blood invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation, nourishing the liver and kidney, replenishing vital essence to improve eyesight, spleen invigorating effect, removing toxic substances, dehumidifying, easing joint movement effect.
Embodiment 3
A kind of Rhizoma Dioscoreae Rhizoma Polygonati capsule, it is made up according to following weight proportion of each component: it is made up according to following weight proportion of each component: Rhizoma Dioscoreae 5900 parts, Radix Ginseng 900 parts, Radix Angelicae Sinensis 2900 parts, Fructus Lycii 2900 parts, Rhizoma Polygonati 3000 parts, 3000 parts, Poria.
The preparation method of described Rhizoma Dioscoreae Rhizoma Polygonati capsule, comprises the steps:
Step 1: sterilization: the Radix Angelicae Sinensis Co60 radiation sterilizing getting the Radix Ginseng of recipe quantity and 2/3rds of recipe quantity respectively;
Step 2: dry: the medical material after step 1 being sterilized dries;
Step 3: pulverize: dried for step 2 medical material is carried out pulverization process, and powder particle diameter is not more than 120 orders;
Step 4: draw materials: get respectively the Rhizoma Dioscoreae of recipe quantity, Fructus Lycii, Rhizoma Polygonati, Poria and recipe quantity 1/3rd Radix Angelicae Sinensis put into extract and fill with;
Step 5: warm macerating again: add in the mixture that step 4 is obtained be step 4 draw materials gross mass 8 times pure water after in 40 DEG C ~ 50 DEG C warm macerating 1 hour;
Step 6: first time heats decoction: by the mixture heating decoction after step 5 warm macerating 2 hours;
Step 7: filter: the 100 order stainless (steel) wires of the mixture after step 6 being decocted filter, obtains first time filtrate;
Step 8: second time heats decoction: adding in the medicinal residues after step 6 being filtered is that the draw materials pure water post-heating of gross mass 6 times of step 4 decocts 1.5 hours;
Step 9: refilter: the 100 order stainless (steel) wires of the mixture after step 8 being decocted filter, obtains second time filtrate;
Step 10: merge: first time filtrate is combined with second time filtrate;
Step 11: concentrated: the liquid after merging puts into decompression concentrator, and reduced pressure atmosphere is: vacuum 0.06-0.08MPa, and temperature is 80 DEG C, adding hot filtrate, to be concentrated into relative density be 1.15 ~ 1.25;
Step 12: mixing: get Radix Ginseng that step 3 obtains and Radix Angelicae Sinensis fine powder and add mixing granulation in concentrated solution that step 11 obtains, every weight is 0.4g;
Step 13: dry: granule step 12 obtained is dried in 60-80 DEG C of environment, and ensure moisture content≤5%;
Step 14: capsule shells filling: the granule of step 13 drying and processing is utilized Autocapsulefillingmachine, is filled into obtained capsule in capsule shells;
Step 15: polishing inspection: capsule shells is carried out polishing inspection, obtains outer wall gloss, without bur;
Step 16: outer package: capsule step 15 obtained utilizes full-automatic overwrapping machine and full-automatic label sticking machine to carry out outer package;
Step 17: warehouse-in: packaged for step 16 capsule is put into warehouse.
The present invention has the following advantages: the present invention is by Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, the Rhizoma Dioscoreae Rhizoma Polygonati capsule that Rhizoma Polygonati and Poria are made according to fixed weight proportioning, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are natural material, proportioning raw materials advantages of simple, effect of each raw material complements each other, it is good health care medicine, Rhizoma Dioscoreae is nutritious because of it, just be regarded as inexpensive tonify deficiency good merchantable brand since ancient times, both staple food grain can be made, vegetable can be done again, adhesive component in RHIIZOMA DIOSCOREAE fr0m Henan of China is made up of the complex of mucoprotein this sugar and protein, mucoprotein have the effect activating androgen, RHIIZOMA DIOSCOREAE fr0m Henan of China has strengthening the spleen and tonifying the lung in a word, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will is calmed the nerves, effect of life lengthening, for weakness of the spleen and stomach, diet reduces, suffer from diarrhoea in loose stool, women's lukorrhagia due to hypofunction of the spleen, chronic cough of deficiency lung dry pharynx, emission due to deficiency of the kidney, Fructus Lycii cures mainly nourishing the liver and kidney, replenishing vital essence to improve eyesight, for asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is failed to understand, containing 14 seed amino acids in Fructus Lycii, and containing special dietary compositions such as betanin, beautiful another name for Sichuan Province flavin, physalins, make it have outstanding health-care effect, Fructus Lycii contains the required nutrient substance of abundant carotene, multivitamin and the healthy eye such as calcium, ferrum, therefore has the merit of improving eyesight, is commonly called as " bright eye ", the superfine product that Radix Ginseng is described as from ancient times " king of BAICAO " " YIN nourishing is mended raw, strengthening the body resistance ", containing multiple Saponin and polysaccharide composition, leachate slowly can be absorbed by skin and without pessimal stimulation, energy skin expansion blood capillary, promotes cutaneous circulation, increase skin-nourishing, the water oil balance of regulation of skin, prevents skin dehydration, sclerosis, wrinkling, the reducing property of Radix Ginseng active substance check melanin, make skin pure white smooth, can strengthen skin elasticity, cell be obtained newborn, be the superfine product of improving looks, Radix Angelicae Sinensis can be enriched blood, and can invigorate blood circulation again, is referred to as and blood, has to enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, Rhizoma Polygonati has benefit vital essence, controls weakness of the spleen and stomach, fatigue and lack of strength, strengthening bone and muscle, effect of beneficial marrow, Poria is containing pachyman, glucose, protein, aminoacid, organic acid, fat, lecithin, adenine, choline, ergosterol, multiple enzyme and potassium salt, energy enhancing human body immunity function, pachyman has obvious antitumor action, there is diuresis, the electrolytical discharge such as potassium, sodium, chlorine in urine can be increased, have the effect such as generation, blood sugar lowering, anti-radiation of calmness and the liver protecting, suppression ulcer, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are made capsule according to fixed weight proportioning by the present invention, there is drug effect, good health promoting product, for people provide convenience, the present invention has spleen reinforcing nourishing the stomach in a word, the lung benefiting that promotes the production of body fluid, strongly invigorating primordial QI, multiple arteries and veins take off admittedly, enrich blood invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation, nourishing the liver and kidney, replenishing vital essence to improve eyesight, spleen invigorating effect, removing toxic substances, dehumidifying, easing joint movement effect.
Embodiment 4
A kind of Rhizoma Dioscoreae Rhizoma Polygonati capsule, it is made up according to following weight proportion of each component: it is made up according to following weight proportion of each component: Rhizoma Dioscoreae 6100 parts, Radix Ginseng 1100 parts, Radix Angelicae Sinensis 3000 parts, Fructus Lycii 3100 parts, Rhizoma Polygonati 3100 parts, 3000 parts, Poria.
The preparation method of described Rhizoma Dioscoreae Rhizoma Polygonati capsule, comprises the steps:
Step 1: sterilization: the Radix Angelicae Sinensis Co60 radiation sterilizing getting the Radix Ginseng of recipe quantity and 2/3rds of recipe quantity respectively;
Step 2: dry: the medical material after step 1 being sterilized dries;
Step 3: pulverize: dried for step 2 medical material is carried out pulverization process, and powder particle diameter is not more than 120 orders;
Step 4: draw materials: get respectively the Rhizoma Dioscoreae of recipe quantity, Fructus Lycii, Rhizoma Polygonati, Poria and recipe quantity 1/3rd Radix Angelicae Sinensis put into extract and fill with;
Step 5: warm macerating again: add in the mixture that step 4 is obtained be step 4 draw materials gross mass 8 times pure water after in 40 DEG C ~ 50 DEG C warm macerating 1 hour;
Step 6: first time heats decoction: by the mixture heating decoction after step 5 warm macerating 2 hours;
Step 7: filter: the 100 order stainless (steel) wires of the mixture after step 6 being decocted filter, obtains first time filtrate;
Step 8: second time heats decoction: adding in the medicinal residues after step 6 being filtered is that the draw materials pure water post-heating of gross mass 6 times of step 4 decocts 1.5 hours;
Step 9: refilter: the 100 order stainless (steel) wires of the mixture after step 8 being decocted filter, obtains second time filtrate;
Step 10: merge: first time filtrate is combined with second time filtrate;
Step 11: concentrated: the liquid after merging puts into decompression concentrator, and reduced pressure atmosphere is: vacuum 0.06-0.08MPa, and temperature is 80 DEG C, adding hot filtrate, to be concentrated into relative density be 1.15 ~ 1.25;
Step 12: mixing: get Radix Ginseng that step 3 obtains and Radix Angelicae Sinensis fine powder and add mixing granulation in concentrated solution that step 11 obtains, every weight is 0.4g;
Step 13: dry: granule step 12 obtained is dried in 60-80 DEG C of environment, and ensure moisture content≤5%;
Step 14: capsule shells filling: the granule of step 13 drying and processing is utilized Autocapsulefillingmachine, is filled into obtained capsule in capsule shells;
Step 15: polishing inspection: capsule shells is carried out polishing inspection, obtains outer wall gloss, without bur;
Step 16: outer package: capsule step 15 obtained utilizes full-automatic overwrapping machine and full-automatic label sticking machine to carry out outer package;
Step 17: warehouse-in: packaged for step 16 capsule is put into warehouse.
The present invention has the following advantages: the present invention is by Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, the Rhizoma Dioscoreae Rhizoma Polygonati capsule that Rhizoma Polygonati and Poria are made according to fixed weight proportioning, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are natural material, proportioning raw materials advantages of simple, effect of each raw material complements each other, it is good health care medicine, Rhizoma Dioscoreae is nutritious because of it, just be regarded as inexpensive tonify deficiency good merchantable brand since ancient times, both staple food grain can be made, vegetable can be done again, adhesive component in RHIIZOMA DIOSCOREAE fr0m Henan of China is made up of the complex of mucoprotein this sugar and protein, mucoprotein have the effect activating androgen, RHIIZOMA DIOSCOREAE fr0m Henan of China has strengthening the spleen and tonifying the lung in a word, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will is calmed the nerves, effect of life lengthening, for weakness of the spleen and stomach, diet reduces, suffer from diarrhoea in loose stool, women's lukorrhagia due to hypofunction of the spleen, chronic cough of deficiency lung dry pharynx, emission due to deficiency of the kidney, Fructus Lycii cures mainly nourishing the liver and kidney, replenishing vital essence to improve eyesight, for asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is failed to understand, containing 14 seed amino acids in Fructus Lycii, and containing special dietary compositions such as betanin, beautiful another name for Sichuan Province flavin, physalins, make it have outstanding health-care effect, Fructus Lycii contains the required nutrient substance of abundant carotene, multivitamin and the healthy eye such as calcium, ferrum, therefore has the merit of improving eyesight, is commonly called as " bright eye ", the superfine product that Radix Ginseng is described as from ancient times " king of BAICAO " " YIN nourishing is mended raw, strengthening the body resistance ", containing multiple Saponin and polysaccharide composition, leachate slowly can be absorbed by skin and without pessimal stimulation, energy skin expansion blood capillary, promotes cutaneous circulation, increase skin-nourishing, the water oil balance of regulation of skin, prevents skin dehydration, sclerosis, wrinkling, the reducing property of Radix Ginseng active substance check melanin, make skin pure white smooth, can strengthen skin elasticity, cell be obtained newborn, be the superfine product of improving looks, Radix Angelicae Sinensis can be enriched blood, and can invigorate blood circulation again, is referred to as and blood, has to enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, Rhizoma Polygonati has benefit vital essence, controls weakness of the spleen and stomach, fatigue and lack of strength, strengthening bone and muscle, effect of beneficial marrow, Poria is containing pachyman, glucose, protein, aminoacid, organic acid, fat, lecithin, adenine, choline, ergosterol, multiple enzyme and potassium salt, energy enhancing human body immunity function, pachyman has obvious antitumor action, there is diuresis, the electrolytical discharge such as potassium, sodium, chlorine in urine can be increased, have the effect such as generation, blood sugar lowering, anti-radiation of calmness and the liver protecting, suppression ulcer, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are made capsule according to fixed weight proportioning by the present invention, there is drug effect, good health promoting product, for people provide convenience, the present invention has spleen reinforcing nourishing the stomach in a word, the lung benefiting that promotes the production of body fluid, strongly invigorating primordial QI, multiple arteries and veins take off admittedly, enrich blood invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation, nourishing the liver and kidney, replenishing vital essence to improve eyesight, spleen invigorating effect, removing toxic substances, dehumidifying, easing joint movement effect.
Embodiment 5
A kind of Rhizoma Dioscoreae Rhizoma Polygonati capsule, it is made up according to following weight proportion of each component: it is made up according to following weight proportion of each component: Rhizoma Dioscoreae 6200 parts, Radix Ginseng 1200 parts, Radix Angelicae Sinensis 3200 parts, Fructus Lycii 3200 parts, Rhizoma Polygonati 3200 parts, 3200 parts, Poria.
The preparation method of described Rhizoma Dioscoreae Rhizoma Polygonati capsule, comprises the steps:
Step 1: sterilization: the Radix Angelicae Sinensis Co60 radiation sterilizing getting the Radix Ginseng of recipe quantity and 2/3rds of recipe quantity respectively;
Step 2: dry: the medical material after step 1 being sterilized dries;
Step 3: pulverize: dried for step 2 medical material is carried out pulverization process, and powder particle diameter is not more than 120 orders;
Step 4: draw materials: get respectively the Rhizoma Dioscoreae of recipe quantity, Fructus Lycii, Rhizoma Polygonati, Poria and recipe quantity 1/3rd Radix Angelicae Sinensis put into extract and fill with;
Step 5: warm macerating again: add in the mixture that step 4 is obtained be step 4 draw materials gross mass 8 times pure water after in 40 DEG C ~ 50 DEG C warm macerating 1 hour;
Step 6: first time heats decoction: by the mixture heating decoction after step 5 warm macerating 2 hours;
Step 7: filter: the 100 order stainless (steel) wires of the mixture after step 6 being decocted filter, obtains first time filtrate;
Step 8: second time heats decoction: adding in the medicinal residues after step 6 being filtered is that the draw materials pure water post-heating of gross mass 6 times of step 4 decocts 1.5 hours;
Step 9: refilter: the 100 order stainless (steel) wires of the mixture after step 8 being decocted filter, obtains second time filtrate;
Step 10: merge: first time filtrate is combined with second time filtrate;
Step 11: concentrated: the liquid after merging puts into decompression concentrator, and reduced pressure atmosphere is: vacuum 0.06-0.08MPa, and temperature is 80 DEG C, adding hot filtrate, to be concentrated into relative density be 1.15 ~ 1.25;
Step 12: mixing: get Radix Ginseng that step 3 obtains and Radix Angelicae Sinensis fine powder and add mixing granulation in concentrated solution that step 11 obtains, every weight is 0.4g;
Step 13: dry: granule step 12 obtained is dried in 60-80 DEG C of environment, and ensure moisture content≤5%;
Step 14: capsule shells filling: the granule of step 13 drying and processing is utilized Autocapsulefillingmachine, is filled into obtained capsule in capsule shells;
Step 15: polishing inspection: capsule shells is carried out polishing inspection, obtains outer wall gloss, without bur;
Step 16: outer package: capsule step 15 obtained utilizes full-automatic overwrapping machine and full-automatic label sticking machine to carry out outer package;
Step 17: warehouse-in: packaged for step 16 capsule is put into warehouse.
The present invention has the following advantages: the present invention is by Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, the Rhizoma Dioscoreae Rhizoma Polygonati capsule that Rhizoma Polygonati and Poria are made according to fixed weight proportioning, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are natural material, proportioning raw materials advantages of simple, effect of each raw material complements each other, it is good health care medicine, Rhizoma Dioscoreae is nutritious because of it, just be regarded as inexpensive tonify deficiency good merchantable brand since ancient times, both staple food grain can be made, vegetable can be done again, adhesive component in RHIIZOMA DIOSCOREAE fr0m Henan of China is made up of the complex of mucoprotein this sugar and protein, mucoprotein have the effect activating androgen, RHIIZOMA DIOSCOREAE fr0m Henan of China has strengthening the spleen and tonifying the lung in a word, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will is calmed the nerves, effect of life lengthening, for weakness of the spleen and stomach, diet reduces, suffer from diarrhoea in loose stool, women's lukorrhagia due to hypofunction of the spleen, chronic cough of deficiency lung dry pharynx, emission due to deficiency of the kidney, Fructus Lycii cures mainly nourishing the liver and kidney, replenishing vital essence to improve eyesight, for asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is failed to understand, containing 14 seed amino acids in Fructus Lycii, and containing special dietary compositions such as betanin, beautiful another name for Sichuan Province flavin, physalins, make it have outstanding health-care effect, Fructus Lycii contains the required nutrient substance of abundant carotene, multivitamin and the healthy eye such as calcium, ferrum, therefore has the merit of improving eyesight, is commonly called as " bright eye ", the superfine product that Radix Ginseng is described as from ancient times " king of BAICAO " " YIN nourishing is mended raw, strengthening the body resistance ", containing multiple Saponin and polysaccharide composition, leachate slowly can be absorbed by skin and without pessimal stimulation, energy skin expansion blood capillary, promotes cutaneous circulation, increase skin-nourishing, the water oil balance of regulation of skin, prevents skin dehydration, sclerosis, wrinkling, the reducing property of Radix Ginseng active substance check melanin, make skin pure white smooth, can strengthen skin elasticity, cell be obtained newborn, be the superfine product of improving looks, Radix Angelicae Sinensis can be enriched blood, and can invigorate blood circulation again, is referred to as and blood, has to enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, Rhizoma Polygonati has benefit vital essence, controls weakness of the spleen and stomach, fatigue and lack of strength, strengthening bone and muscle, effect of beneficial marrow, Poria is containing pachyman, glucose, protein, aminoacid, organic acid, fat, lecithin, adenine, choline, ergosterol, multiple enzyme and potassium salt, energy enhancing human body immunity function, pachyman has obvious antitumor action, there is diuresis, the electrolytical discharge such as potassium, sodium, chlorine in urine can be increased, have the effect such as generation, blood sugar lowering, anti-radiation of calmness and the liver protecting, suppression ulcer, Rhizoma Dioscoreae, Radix Ginseng, Radix Angelicae Sinensis, Fructus Lycii, Rhizoma Polygonati and Poria are made capsule according to fixed weight proportioning by the present invention, there is drug effect, good health promoting product, for people provide convenience, the present invention has spleen reinforcing nourishing the stomach in a word, the lung benefiting that promotes the production of body fluid, strongly invigorating primordial QI, multiple arteries and veins take off admittedly, enrich blood invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation, nourishing the liver and kidney, replenishing vital essence to improve eyesight, spleen invigorating effect, removing toxic substances, dehumidifying, easing joint movement effect.
Taste criticism experiment is carried out to the above embodiment of the present invention gained Rhizoma Dioscoreae Rhizoma Polygonati capsule, through the trial test of 50 people, there are 45 people to represent to like effect of menstruction regulating and pain relieving of the present invention, spleen reinforcing nourishing the stomach, there are 2 people to represent not like effect of menstruction regulating and pain relieving of the present invention, spleen reinforcing nourishing the stomach, remain 3 people represent menstruction regulating and pain relieving of the present invention, spleen reinforcing nourishing the stomach effect sensation general, as can be seen here, the popular reception of effect to menstruction regulating and pain relieving of the present invention, spleen reinforcing nourishing the stomach degree is very high.
Edible example 1: permitted so-and-so, female, 22 years old, dysmenorrhea patient, show as: occur lower abdominal pain, falling inflation through front and back or menstrual phase, with the soreness of waist or other discomforts, serious symptom affects quality of life person, after adopting the Rhizoma Dioscoreae Rhizoma Polygonati capsule of menstruction regulating and pain relieving effect of the present invention, pain relief, to improve the complexion, and in use after 20 days, pain almost disappears, life is also basic recovers normal.
Edible example 2: Lee so-and-so, man, 29 years old, the bad patient of taste, show as: mental weariness, deficiency of QI with disinclination to talk, fatigue and weak, sleepy, inappetence after food, after adopting the Rhizoma Dioscoreae Rhizoma Polygonati capsule of spleen reinforcing nourishing the stomach effect of the present invention, spirit takes a turn for the better, appetite is got better, and in use after 15 days, the mental status is fine, and appetite also increases.

Claims (3)

1. a Rhizoma Dioscoreae Rhizoma Polygonati capsule, is characterized in that: it is made up according to following weight proportion of each component: Rhizoma Dioscoreae 5800-6200 part, Radix Ginseng 800-1200 part, Radix Angelicae Sinensis 2800-3200 part, Fructus Lycii 2800-3200 part, Rhizoma Polygonati 2800-3200 part, Poria 2800-3200 part.
2. a kind of Rhizoma Dioscoreae Rhizoma Polygonati capsule as claimed in claim 1, is characterized in that: it is made up according to following weight proportion of each component: Rhizoma Dioscoreae 6000 parts, Radix Ginseng 1000 parts, Radix Angelicae Sinensis 3000 parts, Fructus Lycii 3000 parts, Rhizoma Polygonati 3000 parts, 3000 parts, Poria.
3. a preparation method for the Rhizoma Dioscoreae Rhizoma Polygonati capsule as described in as arbitrary in claim 1-2, is characterized in that: described preparation method comprises the steps:
Step 1: sterilization: the Radix Angelicae Sinensis Co60 radiation sterilizing getting the Radix Ginseng of recipe quantity and 2/3rds of recipe quantity respectively;
Step 2: dry: the medical material after step 1 being sterilized dries;
Step 3: pulverize: dried for step 2 medical material is carried out pulverization process, and powder particle diameter is not more than 120 orders;
Step 4: draw materials: get respectively the Rhizoma Dioscoreae of recipe quantity, Fructus Lycii, Rhizoma Polygonati, Poria and recipe quantity 1/3rd Radix Angelicae Sinensis put into extract and fill with;
Step 5: warm macerating again: add in the mixture that step 4 is obtained be step 4 draw materials gross mass 8 times pure water after in 40 DEG C ~ 50 DEG C warm macerating 1 hour;
Step 6: first time heats decoction: by the mixture heating decoction after step 5 warm macerating 2 hours;
Step 7: filter: the 100 order stainless (steel) wires of the mixture after step 6 being decocted filter, obtains first time filtrate;
Step 8: second time heats decoction: adding in the medicinal residues after step 6 being filtered is that the draw materials pure water post-heating of gross mass 6 times of step 4 decocts 1.5 hours;
Step 9: refilter: the 100 order stainless (steel) wires of the mixture after step 8 being decocted filter, obtains second time filtrate;
Step 10: merge: first time filtrate is combined with second time filtrate;
Step 11: concentrated: the liquid after merging puts into decompression concentrator, and reduced pressure atmosphere is: vacuum 0.06-0.08MPa, and temperature is 80 DEG C, adding hot filtrate, to be concentrated into relative density be 1.15 ~ 1.25;
Step 12: mixing: get Radix Ginseng that step 3 obtains and Radix Angelicae Sinensis fine powder and add mixing granulation in concentrated solution that step 11 obtains, every weight is 0.4g;
Step 13: dry: granule step 12 obtained is dried in 60-80 DEG C of environment, and ensure moisture content≤5%;
Step 14: capsule shells filling: the granule of step 13 drying and processing is utilized Autocapsulefillingmachine, is filled into obtained capsule in capsule shells;
Step 15: polishing inspection: capsule shells is carried out polishing inspection, obtains outer wall gloss, without bur;
Step 16: outer package: capsule step 15 obtained utilizes full-automatic overwrapping machine and full-automatic label sticking machine to carry out outer package;
Step 17: warehouse-in: packaged for step 16 capsule is put into warehouse.
CN201410486433.2A 2014-09-23 2014-09-23 Chinese yam-rhizoma polygonati capsule and preparation method thereof Pending CN104288495A (en)

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Cited By (10)

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CN105747073A (en) * 2016-05-20 2016-07-13 南京汉钦食品有限公司 Medicinal and edible plant solid beverage and preparation method thereof
CN106912947A (en) * 2017-03-02 2017-07-04 芜湖张恒春药业有限公司 The compound cream and preparation method thereof that takes care of health of one kind
CN108185077A (en) * 2018-02-22 2018-06-22 山东芝圣堂生物科技有限公司 A kind of sealwort mulberry fruit production method for tea for contributing to men's health
CN108403928A (en) * 2018-04-18 2018-08-17 北京理工亘舒科技有限公司 A kind of herbal cuisine element product of strengthen immunity and preparation method thereof
CN108991529A (en) * 2018-08-22 2018-12-14 湖南中医药大学 The food compositions and preparation method thereof of member are supported in a kind of invigorating the spleen
CN109452647A (en) * 2018-11-17 2019-03-12 恩施州源惠科技开发有限公司 A kind of Manyflower solomonseal rhizome food and preparation method thereof
CN109646590A (en) * 2018-12-27 2019-04-19 北京康比特体育科技股份有限公司 A kind of composition and its application for preventing to move low blood testis
WO2022062716A1 (en) * 2020-09-25 2022-03-31 江苏康缘药业股份有限公司 Composition having function of nourishing yin and tonifying kidney, and preparation method therefor and use thereof
CN114381349A (en) * 2022-01-19 2022-04-22 成都非凡生物高新科技有限公司 SOD wine capable of preserving health and tonifying kidney and preparation method thereof
CN114452351A (en) * 2020-11-08 2022-05-10 张果达 Health-preserving traditional Chinese medicine for controlling body figure and keeping young vigor

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105747073A (en) * 2016-05-20 2016-07-13 南京汉钦食品有限公司 Medicinal and edible plant solid beverage and preparation method thereof
CN106912947A (en) * 2017-03-02 2017-07-04 芜湖张恒春药业有限公司 The compound cream and preparation method thereof that takes care of health of one kind
CN108185077A (en) * 2018-02-22 2018-06-22 山东芝圣堂生物科技有限公司 A kind of sealwort mulberry fruit production method for tea for contributing to men's health
CN108403928A (en) * 2018-04-18 2018-08-17 北京理工亘舒科技有限公司 A kind of herbal cuisine element product of strengthen immunity and preparation method thereof
CN108991529A (en) * 2018-08-22 2018-12-14 湖南中医药大学 The food compositions and preparation method thereof of member are supported in a kind of invigorating the spleen
CN108991529B (en) * 2018-08-22 2021-09-03 湖南中医药大学 Food composition for invigorating spleen and nourishing vitality and preparation method thereof
CN109452647A (en) * 2018-11-17 2019-03-12 恩施州源惠科技开发有限公司 A kind of Manyflower solomonseal rhizome food and preparation method thereof
CN109646590A (en) * 2018-12-27 2019-04-19 北京康比特体育科技股份有限公司 A kind of composition and its application for preventing to move low blood testis
WO2022062716A1 (en) * 2020-09-25 2022-03-31 江苏康缘药业股份有限公司 Composition having function of nourishing yin and tonifying kidney, and preparation method therefor and use thereof
CN114452351A (en) * 2020-11-08 2022-05-10 张果达 Health-preserving traditional Chinese medicine for controlling body figure and keeping young vigor
CN114381349A (en) * 2022-01-19 2022-04-22 成都非凡生物高新科技有限公司 SOD wine capable of preserving health and tonifying kidney and preparation method thereof

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Application publication date: 20150121