CN104288483A - Medicament for treating upper respiratory infection - Google Patents

Medicament for treating upper respiratory infection Download PDF

Info

Publication number
CN104288483A
CN104288483A CN201410458172.3A CN201410458172A CN104288483A CN 104288483 A CN104288483 A CN 104288483A CN 201410458172 A CN201410458172 A CN 201410458172A CN 104288483 A CN104288483 A CN 104288483A
Authority
CN
China
Prior art keywords
parts
herba
radix
medicament
lagotis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410458172.3A
Other languages
Chinese (zh)
Inventor
韩先章
刘志鸿
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201410458172.3A priority Critical patent/CN104288483A/en
Publication of CN104288483A publication Critical patent/CN104288483A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/10Bryophyta (mosses)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/282Organic compounds, e.g. fats
    • A61K9/2826Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a medicament for treating upper respiratory infection. The medicament for treating upper respiratory infection is prepared from the following ingredients, by weight, 40-60 parts of sheepear inula herb, 40-60 parts of Haplocladium microphyllum, 25-35 parts of Euphorbia kansui, 25-35 parts of Artemisia capillaries, 20-30 parts of common bluebeard herb, 10-20 parts of subprostrate sophora, 10-20 parts of Andrographis paniculata Nees, 10-20 parts of isatis root, 3-8 parts of Lagotis clarkei Hook. F., 3-8 parts of borneol and 3-8 parts of Radix Ophiopogonis. According to the invention, sheepear inula herb and Haplocladium microphyllum are used as ministerial drugs, Euphorbia kansui, Artemisia capillaries, common bluebeard herb, subprostrate sophora and Andrographis paniculata Nees are used as ministerial drugs, and isatis root, Lagotis clarkei Hook. F., borneol and Radix Ophiopogonis are used as adjuvant drugs, so as to prepare the medicament. With compatibility of various drugs, by unite efforts of the principal and ministerial drugs and with the assistance of the adjuvant drugs, the medicament has effects of dispelling wind and heat, moistening lung, reducing phlegm, diffusing the lung and relieving cough, and helps nourish the stomach and spleen. Then, the purpose of treating upper respiratory infection fundamentally is achieved.

Description

A kind of medicament for the treatment of upper respiratory tract infection
Technical field
The present invention relates to the medication of a kind of Pneumology Department common disease, particularly a kind of medicament for the treatment of upper respiratory tract infection.
Background technology
By virus or bacterial upper respiratory tract infection be commonly encountered diseases, so various types of medicine is more.Present somebody likes taking antibiotic, but antibiotic easily causes mattress group to lack of proper care and bacterial resistance.Considerable antibacterial is there is, in the tract that skin, respiratory tract, intestinal etc. that antibacterial is mainly present in people communicate with the external world in human body.These beneficial bacterias play protective effect to human body.When external pathogenic bacterium enter human body, if amount is not very large, just cannot compete with the original a large amount of antibacterial of human body and survive, when people takes antibiotic, the normal mattress group of human body can partly be killed, thus makes human body lose protective capacities.Because antibiotic side effect is large, first patient generally selects Chinese patent drugs for treatment, and therapeutic effect rare in current pure Chinese medicine product is good, effective fast kind.
Summary of the invention
The technical problem to be solved in the present invention is the above-mentioned defect how overcoming prior art, provides a kind of medicament for the treatment of upper respiratory tract infection.
For solving the problems of the technologies described above, the medicament of this treatment upper respiratory tract infection is prepared according to shown weight ratio scope by following component, the little plumage moss of Herba Inulae cappae 40 ~ 60 parts, spire 40 ~ 60 parts, Radix Kansui 25 ~ 35 parts, Herba Artemisiae Scopariae 25 ~ 35 parts, Herba Caryopteridis Incanae 20 ~ 30 parts, Radix Sophorae Tonkinensis 10 ~ 20 parts, Herba Andrographis 10 ~ 20 parts, Radix Isatidis 10 ~ 20 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 3 ~ 8 parts, Borneolum Syntheticum 3 ~ 8 parts, Radix Ophiopogonis 3 ~ 8 parts.
As optimum ratio scope, described medicament is prepared according to shown weight ratio scope by following component, the little plumage moss of Herba Inulae cappae 49 ~ 51 parts, spire 49 ~ 51 parts, Radix Kansui 29 ~ 31 parts, Herba Artemisiae Scopariae 29 ~ 31 parts, Herba Caryopteridis Incanae 29 ~ 31 parts, Radix Sophorae Tonkinensis 14 ~ 16 parts, Herba Andrographis 14 ~ 16 parts, Radix Isatidis 14 ~ 16 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 5 ~ 7 parts, Borneolum Syntheticum 5 ~ 7 parts, Radix Ophiopogonis 5 ~ 7 parts.
As optimum ratio, described medicament is prepared according to shown weight ratio by following component, the little plumage moss of Herba Inulae cappae 60 parts, spire 40 parts, Radix Kansui 35 parts, Herba Artemisiae Scopariae 25 parts, Herba Caryopteridis Incanae 30 parts, Radix Sophorae Tonkinensis 10 parts, Herba Andrographis 20 parts, Radix Isatidis 10 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 8 parts, Borneolum Syntheticum 3 parts, Radix Ophiopogonis 8 parts.
As optimum ratio, described medicament is prepared according to shown weight ratio by following component, the little plumage moss of Herba Inulae cappae 40 parts, spire 60 parts, Radix Kansui 25 parts, Herba Artemisiae Scopariae 35 parts, Herba Caryopteridis Incanae 20 parts, Radix Sophorae Tonkinensis 20 parts, Herba Andrographis 10 parts, Radix Isatidis 20 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 3 parts, Borneolum Syntheticum 8 parts, Radix Ophiopogonis 3 parts.
As further optimum ratio, described medicament is prepared according to shown weight ratio by following component, the little plumage moss of Herba Inulae cappae 51 parts, spire 49 parts, Radix Kansui 31 parts, Herba Artemisiae Scopariae 29 parts, Herba Caryopteridis Incanae 31 parts, Radix Sophorae Tonkinensis 14 parts, Herba Andrographis 16 parts, Radix Isatidis 14 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 7 parts, Borneolum Syntheticum 5 parts, Radix Ophiopogonis 7 parts.
As further optimum ratio, described medicament is prepared according to shown weight ratio by following component, the little plumage moss of Herba Inulae cappae 49 parts, spire 51 parts, Radix Kansui 29 parts, Herba Artemisiae Scopariae 31 parts, Herba Caryopteridis Incanae 29 parts, Radix Sophorae Tonkinensis 16 parts, Herba Andrographis 146 parts, Radix Isatidis 16 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 5 parts, Borneolum Syntheticum 7 parts, Radix Ophiopogonis 5 parts.
As optimum proportioning, described medicament is prepared according to shown weight ratio by following component, the little plumage moss of Herba Inulae cappae 50 parts, spire 50 parts, Radix Kansui 30 parts, Herba Artemisiae Scopariae 30 parts, Herba Caryopteridis Incanae 30 parts, Radix Sophorae Tonkinensis 15 parts, Herba Andrographis 15 parts, Radix Isatidis 15 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 6 parts, Borneolum Syntheticum 6 parts, Radix Ophiopogonis 6 parts.
The medicament of this treatment upper respiratory tract infection is coated tablet, its preparation method is, by Herba Inulae cappae, the little plumage moss of spire, Radix Kansui, Herba Artemisiae Scopariae, Herba Caryopteridis Incanae, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Isatidis, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), Borneolum Syntheticum, after weighing by described proportioning Radix Ophiopogonis, Radix Isatidis decocting liquid half amount got makes diluent, the Radix Isatidis of half amount mixes with all the other components in addition, the water soaking adding mixture 10 times amount decocts three times, each hours, the decocting liquid merging three times filters, and be concentrated into paste, add Radix Isatidis liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, ethanol with 80% does binding agent and makes 20 order granules, the magnesium stearate of 1% of granular mass is added after granulate, be pressed into the sugar coated tablet of every sheet containing crude drug 1 gram.
Pharmacology analysis
Herba Inulae cappae: acrid in the mouth, micro-hardship, warm in nature; Expelling cold and relieving exterior syndrome, detumescence of dispeling the wind, promoting the circulation of QI to relieve pain, for anemofrigid cold, cough, nervous headache, stomachache, lumbago, skelalgia of rheumatism, treating swelling and pain by traumatic injury, menoxenia, leucorrhea, schistosomicide.
Spire little plumage moss: bitter in the mouth, pungent, cool in nature; Heat-clearing and toxic substances removing, main acute tonsillitis; Mastitis; Erysipelas; Furuncle and phyma; Upper respiratory tract infection; Pneumonia; Otitis media; Cystitis; Urethritis; Adnexitis; Puerperal infection; The high heat of insect bite.
Radix Kansui: sweet in the mouth, hardship, cold nature; Return lung, urinary bladder channel; Inducing diuresis for treating stranguria syndrome, clearing away heat to stop bleeding, for pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction, drenches the puckery pain of drop, spits blood, epistaxis, hematuria, metrorrhagia, dyspnea and cough due to lung-heat.
Herba Artemisiae Scopariae: bitter in the mouth, pungent, cold nature; Return spleen, stomach, liver, gallbladder meridian; Clearing away damp-heat, jaundice eliminating subcutaneous ulcer, for jaundice oliguria, eczema pruritus; Infectious jaundice type hepatitis.
Herba Caryopteridis Incanae: acrid in the mouth, warm in nature; Dispelling wind to relieve the exterior syndrome, expelling phlegm for arresting cough, scattered silt pain relieving, for upper respiratory tract infection, pertussis, bronchitis, rheumatic arthritis, gastroenteritis, treating swelling and pain by traumatic injury, puerperal abdominalgia with blood stasis; Venom is controlled in external, eczema, skin itching.
Radix Sophorae Tonkinensis: bitter in the mouth, cold in nature; Attach to the lung and stomach meridians; Heat-clearing and toxic substances removing, detumescence sore-throat relieving, pents up for fire-toxin, laryngopharynx swelling and pain, gingivitis.
Herba Andrographis: bitter in the mouth, cold in nature.GUIXIN, lung, large intestine, urinary bladder channel.Heat-clearing and toxic substances removing, pathogenic fire purging, dampness, clinical in anemopyretic cold, epidemic febrile disease is generated heat, cough due to lung-heat, pertussis, lung abscess, laryngopharynx swelling and pain, jaundice due to damp-heat, stranguria, erysipelas, skin infection carbuncle, eczema, venom etc.
Radix Isatidis: bitter in the mouth, cold in nature; GUIXIN, stomach warp; Heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving, for maculae caused by violent heat pathogen, crimson tongue is purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, carbuncle.
Lagotis clarkei Hook. F (Lagotis brevituba Maxim.): bitter in the mouth, sweet, cold in nature; Heat-clearing and toxic substances removing; Blood pressure lowering; Regulating menstruation, main acute, chronic hepatitis, nephritis, lung abscess, hypertension, the moon be uncomfortable, breast carcinoma often.
Borneolum Syntheticum: acrid in the mouth, hardship, cool in nature; GUIXIN, lung meridian; To have one's ideas straightened out refreshment, heat radiation pain relieving, improving eyesight removing nebula, for apoplexy, calentura coma, deafness with qi stagnation, sore throat, aphtha, carbuncle, hemorrhoid, the diseases such as enterobiasis.
Radix Ophiopogonis: sweet in the mouth, micro-hardship, cold nature; GUIXIN, lung, stomach warp; YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire, and for dryness of the lung dry cough, chronic consumptive disease is coughed, and Tianjin wound is thirsty, and vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.
The medicament that the present invention is a kind of treats upper respiratory tract infection with Herba Inulae cappae, the little plumage moss of spire for ministerial drug, with Radix Kansui, Herba Artemisiae Scopariae, Herba Caryopteridis Incanae, Radix Sophorae Tonkinensis, Herba Andrographis for ministerial drug, with Radix Isatidis, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), Borneolum Syntheticum, Radix Ophiopogonis for adjuvant formulated; All medicine compatibilities in side, the monarch and his subjects pull together, help and make auxiliary altogether, make medicine possess dispelling wind and heat pathogens, moistening the lung and resolving phlegm, effect of lung qi dispersing cough-relieving, help and to shake spleen with nourishing the stomach, reach the object of fundamentally curing upper respiratory tract infection.
Detailed description of the invention
Embodiment 1: by Herba Inulae cappae 60g, spire little plumage moss 40g, Radix Kansui 35g, Herba Artemisiae Scopariae 25g, Herba Caryopteridis Incanae 30g, Radix Sophorae Tonkinensis 10g, Herba Andrographis 20g, Radix Isatidis 10g, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 8g, Borneolum Syntheticum 3g, Radix Ophiopogonis, the proportioning of 8g took each component, Radix Isatidis decocting liquid half amount got makes diluent, the Radix Isatidis of half amount mixes with all the other components in addition, the water soaking adding mixture 10 times amount decocts three times, each hours, the decocting liquid merging three times filters, and be concentrated into paste, add Radix Isatidis liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, ethanol with 80% does binding agent and makes 20 order granules, the magnesium stearate of 1% of granular mass is added after granulate, be pressed into the sugar coated tablet of every sheet containing crude drug 1 gram, obtain the medicament coated tablet A of this treatment upper respiratory tract infection.
Embodiment 2: by Herba Inulae cappae 40g, spire little plumage moss 60g, Radix Kansui 25g, Herba Artemisiae Scopariae 35g, Herba Caryopteridis Incanae 20g, Radix Sophorae Tonkinensis 20g, Herba Andrographis 10g, Radix Isatidis 20g, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 3g, Borneolum Syntheticum 8g, Radix Ophiopogonis, the proportioning of 3g took each component, Radix Isatidis decocting liquid half amount got makes diluent, the Radix Isatidis of half amount mixes with all the other components in addition, the water soaking adding mixture 10 times amount decocts three times, each hours, the decocting liquid merging three times filters, and be concentrated into paste, add Radix Isatidis liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, ethanol with 80% does binding agent and makes 20 order granules, the magnesium stearate of 1% of granular mass is added after granulate, be pressed into the sugar coated tablet of every sheet containing crude drug 1 gram, obtain the medicament coated tablet B of this treatment upper respiratory tract infection.
Embodiment 3: by Herba Inulae cappae 51g, spire little plumage moss 49g, Radix Kansui 31g, Herba Artemisiae Scopariae 29g, Herba Caryopteridis Incanae 31g, Radix Sophorae Tonkinensis 14g, Herba Andrographis 16g, Radix Isatidis 14g, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 7g, Borneolum Syntheticum 5g, Radix Ophiopogonis, the proportioning of 7g took each component, Radix Isatidis decocting liquid half amount got makes diluent, the Radix Isatidis of half amount mixes with all the other components in addition, the water soaking adding mixture 10 times amount decocts three times, each hours, the decocting liquid merging three times filters, and be concentrated into paste, add Radix Isatidis liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, ethanol with 80% does binding agent and makes 20 order granules, the magnesium stearate of 1% of granular mass is added after granulate, be pressed into the sugar coated tablet of every sheet containing crude drug 1 gram, obtain the medicament coated tablet C of this treatment upper respiratory tract infection.
Embodiment 4: by Herba Inulae cappae 49g, spire little plumage moss 51g, Radix Kansui 29g, Herba Artemisiae Scopariae 31g, Herba Caryopteridis Incanae 29g, Radix Sophorae Tonkinensis 16g, Herba Andrographis 146g, Radix Isatidis 16g, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 5g, Borneolum Syntheticum 7g, Radix Ophiopogonis, the proportioning of 5g took each component, Radix Isatidis decocting liquid half amount got makes diluent, the Radix Isatidis of half amount mixes with all the other components in addition, the water soaking adding mixture 10 times amount decocts three times, each hours, the decocting liquid merging three times filters, and be concentrated into paste, add Radix Isatidis liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, ethanol with 80% does binding agent and makes 20 order granules, the magnesium stearate of 1% of granular mass is added after granulate, be pressed into the sugar coated tablet of every sheet containing crude drug 1 gram, obtain the medicament coated tablet D of this treatment upper respiratory tract infection.
Embodiment 5: by Herba Inulae cappae 50g, spire little plumage moss 50g, Radix Kansui 30g, Herba Artemisiae Scopariae 30g, Herba Caryopteridis Incanae 30g, Radix Sophorae Tonkinensis 15g, Herba Andrographis 15g, Radix Isatidis 15g, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 6g, Borneolum Syntheticum 6g, Radix Ophiopogonis, the proportioning of 6g took each component, Radix Isatidis decocting liquid half amount got makes diluent, the Radix Isatidis of half amount mixes with all the other components in addition, the water soaking adding mixture 10 times amount decocts three times, each hours, the decocting liquid merging three times filters, and be concentrated into paste, add Radix Isatidis liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, ethanol with 80% does binding agent and makes 20 order granules, the magnesium stearate of 1% of granular mass is added after granulate, be pressed into the sugar coated tablet of every sheet containing crude drug 1 gram, obtain the medicament coated tablet E of this treatment upper respiratory tract infection.
In above-described embodiment, embodiment 5 is preferred embodiment.
Clinical data
Case standard: 1. to generate heat (body temperature more than 38 degree), thirsty with aversion to cold, headache, pharyngalgia, cough, xerostomia; 2. tongue tip side of red, white or yellow thin fur; 3. lab testing: hemogram raises, neutrality moves to left.
Case selection: choose patient 100 example meeting above-mentioned standard, wherein man 50 example, female 50 example; Minimal ages 16 years old, max age 60 years old, 34 years old mean age.
Case medication: use the medicament coated tablet E of this treatment upper respiratory tract infection obtained in embodiment 5 to treat, wherein one day three times, each two panels, treating seven days is a course for the treatment of.
Evaluation criteria: effective-all front two standards disappeared within 2 days, and a rear standard recovered normal person within the 4th day.Improvement-all front two standards disappeared in 2 to 3 days, and latter one was recovered normal person at the 4 to 6 day.Invalid-front two disappeared within 3 days, and rear one is recovered normal person on the 6th day later.
Efficacy evaluation: through there being the observation of a course for the treatment of, finds that 100 routine patient outcomes are effective, and does not observe obvious untoward reaction at whole treatments period.
Model case
Case 1: journey, female, 40 years old, have dry cough sick, the other day recurred again, and transfusion first quarter moon fork-like farm tool used in ancient China takes effect really, takes a course for the treatment of of medicament coated tablet E of obtained this treatment upper respiratory tract infection of the present embodiment 5, returns to one's perfect health, follow up a case by regular visits to and have no recurrence.
Case 2: Lee, female, 45 years old, have chronic pharyngitis and hypertrophy of tonsils for many years, take traditional Chinese and western drugs and can not effect a radical cure all the time, take a course for the treatment of of medicament coated tablet E of obtained this treatment upper respiratory tract infection of the present embodiment 5, thorough rehabilitation, after adhere to taking this medicine, follow up a case by regular visits to and have no recurrence.
Case 3: grandson, female, 23 years old, has rhinitis for many years, takes traditional Chinese and western drugs and can not effect a radical cure all the time, takes a course for the treatment of of medicament coated tablet E of obtained this treatment upper respiratory tract infection of the present embodiment 5, thorough rehabilitation, after adhere to taking this medicine, follow up a case by regular visits to and have no recurrence.
Case 4: Hu, man, 40 years old, has rhinitis, takes traditional Chinese and western drugs and can not effect a radical cure all the time, takes a course for the treatment of of medicament coated tablet E of obtained this treatment upper respiratory tract infection of the present embodiment 5, thorough rehabilitation, after adhere to taking this medicine, follow up a case by regular visits to and have no recurrence.
Case 5: Jiang, man, 34 years old, there is tracheitis for many years, take traditional Chinese and western drugs and can not effect a radical cure all the time, take a course for the treatment of of medicament coated tablet E of obtained this treatment upper respiratory tract infection of the present embodiment 5, thorough rehabilitation, after adhere to taking this medicine, follow up a case by regular visits to and have no recurrence.
Case 6: Korea Spro, man, 60 years old, there is chronic pharyngitis for many years, take traditional Chinese and western drugs and can not effect a radical cure all the time, take a course for the treatment of of medicament coated tablet E of obtained this treatment upper respiratory tract infection of the present embodiment 5, thorough rehabilitation, after adhere to taking this medicine, follow up a case by regular visits to and have no recurrence.
Case 7: Jiang, female, 16 years old, there is chronic pharyngitis for many years, take traditional Chinese and western drugs and can not effect a radical cure all the time, take a course for the treatment of of medicament coated tablet E of obtained this treatment upper respiratory tract infection of the present embodiment 5, thorough rehabilitation, after adhere to taking this medicine, follow up a case by regular visits to and have no recurrence.
Case 8: Lu, man, more than 22 year old, has rhinitis, takes traditional Chinese and western drugs and can not effect a radical cure all the time, takes a course for the treatment of of medicament coated tablet E of obtained this treatment upper respiratory tract infection of the present embodiment 5, thorough rehabilitation, after adhere to taking this medicine, follow up a case by regular visits to and have no recurrence.
Case 9: in certain, man, 18 years old, heating, temperature 39 DEG C, cough, abundant expectoration, color white matter is rare, gurgling with sputum, receive food still can, two just still adjust, uneasy sleeping at night, light red tongue, and tongue is greasy in vain.Take a course for the treatment of of medicament coated tablet E of obtained this treatment upper respiratory tract infection of the present embodiment 5, symptom thoroughly disappears, after adhere to taking this medicine, follow up a case by regular visits to and have no recurrence.
Case 10: fur coat, female, 26 years old, watery nasal discharge, low grade fever 2 days, acutely cough, tears accompanied each other, and large dry stool is secret, yellowish or reddish urine.Temperature 38.2 DEG C, pharyngeal cavity is slightly red and swollen, both sides antiadoncus, and slightly congested, dry cough is frequent, and two pulmonary respiration sounds are clear, red tongue, yellow and thin fur, and floating and rapid pulse is held concurrently sliding real.Take a course for the treatment of of medicament coated tablet E of obtained this treatment upper respiratory tract infection of the present embodiment 5, symptom thoroughly disappears, after adhere to taking this medicine, follow up a case by regular visits to and have no recurrence.
Above-mentioned embodiment is intended to illustrate that the present invention can be professional and technical personnel in the field and realizes or use; modifying to above-mentioned embodiment will be apparent for those skilled in the art; therefore the present invention includes but be not limited to above-mentioned embodiment; any these claims or description of meeting describes; meet and principle disclosed herein and novelty, the method for inventive features, technique, product, all fall within protection scope of the present invention.

Claims (8)

1. treat the medicament of upper respiratory tract infection for one kind, it is characterized in that: this medicament is prepared according to shown weight ratio scope by following component, the little plumage moss of Herba Inulae cappae 40 ~ 60 parts, spire 40 ~ 60 parts, Radix Kansui 25 ~ 35 parts, Herba Artemisiae Scopariae 25 ~ 35 parts, Herba Caryopteridis Incanae 20 ~ 30 parts, Radix Sophorae Tonkinensis 10 ~ 20 parts, Herba Andrographis 10 ~ 20 parts, Radix Isatidis 10 ~ 20 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 3 ~ 8 parts, Borneolum Syntheticum 3 ~ 8 parts, Radix Ophiopogonis 3 ~ 8 parts.
2. the medicament for the treatment of upper respiratory tract infection according to claim 1, it is characterized in that: described medicament is prepared according to shown weight ratio scope by following component, the little plumage moss of Herba Inulae cappae 49 ~ 51 parts, spire 49 ~ 51 parts, Radix Kansui 29 ~ 31 parts, Herba Artemisiae Scopariae 29 ~ 31 parts, Herba Caryopteridis Incanae 29 ~ 31 parts, Radix Sophorae Tonkinensis 14 ~ 16 parts, Herba Andrographis 14 ~ 16 parts, Radix Isatidis 14 ~ 16 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 5 ~ 7 parts, Borneolum Syntheticum 5 ~ 7 parts, Radix Ophiopogonis 5 ~ 7 parts.
3. the medicament for the treatment of upper respiratory tract infection according to claim 1, it is characterized in that: described medicament is prepared according to shown weight ratio by following component, the little plumage moss of Herba Inulae cappae 60 parts, spire 40 parts, Radix Kansui 35 parts, Herba Artemisiae Scopariae 25 parts, Herba Caryopteridis Incanae 30 parts, Radix Sophorae Tonkinensis 10 parts, Herba Andrographis 20 parts, Radix Isatidis 10 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 8 parts, Borneolum Syntheticum 3 parts, Radix Ophiopogonis 8 parts.
4. the medicament for the treatment of upper respiratory tract infection according to claim 1, it is characterized in that: described medicament is prepared according to shown weight ratio by following component, the little plumage moss of Herba Inulae cappae 40 parts, spire 60 parts, Radix Kansui 25 parts, Herba Artemisiae Scopariae 35 parts, Herba Caryopteridis Incanae 20 parts, Radix Sophorae Tonkinensis 20 parts, Herba Andrographis 10 parts, Radix Isatidis 20 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 3 parts, Borneolum Syntheticum 8 parts, Radix Ophiopogonis 3 parts.
5. the medicament for the treatment of upper respiratory tract infection according to claim 2, it is characterized in that: described medicament is prepared according to shown weight ratio by following component, the little plumage moss of Herba Inulae cappae 51 parts, spire 49 parts, Radix Kansui 31 parts, Herba Artemisiae Scopariae 29 parts, Herba Caryopteridis Incanae 31 parts, Radix Sophorae Tonkinensis 14 parts, Herba Andrographis 16 parts, Radix Isatidis 14 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 7 parts, Borneolum Syntheticum 5 parts, Radix Ophiopogonis 7 parts.
6. the medicament for the treatment of upper respiratory tract infection according to claim 2, it is characterized in that: described medicament is prepared according to shown weight ratio by following component, the little plumage moss of Herba Inulae cappae 49 parts, spire 51 parts, Radix Kansui 29 parts, Herba Artemisiae Scopariae 31 parts, Herba Caryopteridis Incanae 29 parts, Radix Sophorae Tonkinensis 16 parts, Herba Andrographis 146 parts, Radix Isatidis 16 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 5 parts, Borneolum Syntheticum 7 parts, Radix Ophiopogonis 5 parts.
7. the medicament for the treatment of upper respiratory tract infection according to claim 2, it is characterized in that: described medicament is prepared according to shown weight ratio by following component, the little plumage moss of Herba Inulae cappae 50 parts, spire 50 parts, Radix Kansui 30 parts, Herba Artemisiae Scopariae 30 parts, Herba Caryopteridis Incanae 30 parts, Radix Sophorae Tonkinensis 15 parts, Herba Andrographis 15 parts, Radix Isatidis 15 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 6 parts, Borneolum Syntheticum 6 parts, Radix Ophiopogonis 6 parts.
8. according to the medicament of the arbitrary described treatment upper respiratory tract infection of claim 1 to 7, it is characterized in that: described medicament is coated tablet, its preparation method is, by Herba Inulae cappae, the little plumage moss of spire, Radix Kansui, Herba Artemisiae Scopariae, Herba Caryopteridis Incanae, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Isatidis, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), Borneolum Syntheticum, after weighing by described proportioning Radix Ophiopogonis, Radix Isatidis decocting liquid half amount got makes diluent, the Radix Isatidis of half amount mixes with all the other components in addition, the water soaking adding mixture 10 times amount decocts three times, each hours, the decocting liquid merging three times filters, and be concentrated into paste, add Radix Isatidis liquid diluent again to stir and make soft material, dry under 40 ~ 60 DEG C of conditions, be ground into fine powder, ethanol with 80% does binding agent and makes 20 order granules, the magnesium stearate of 1% of granular mass is added after granulate, be pressed into the sugar coated tablet of every sheet containing crude drug 1 gram.
CN201410458172.3A 2014-09-09 2014-09-09 Medicament for treating upper respiratory infection Pending CN104288483A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410458172.3A CN104288483A (en) 2014-09-09 2014-09-09 Medicament for treating upper respiratory infection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410458172.3A CN104288483A (en) 2014-09-09 2014-09-09 Medicament for treating upper respiratory infection

Publications (1)

Publication Number Publication Date
CN104288483A true CN104288483A (en) 2015-01-21

Family

ID=52308594

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410458172.3A Pending CN104288483A (en) 2014-09-09 2014-09-09 Medicament for treating upper respiratory infection

Country Status (1)

Country Link
CN (1) CN104288483A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103142733A (en) * 2013-03-05 2013-06-12 刘风荣 Chinese medicine composition for treating upper respiratory infection
CN103751515A (en) * 2014-01-06 2014-04-30 崔磊 Pharmaceutical composition for treating upper respiratory infection
CN103751517A (en) * 2014-01-06 2014-04-30 崔磊 Pharmaceutical composition for treating chronic bronchitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103142733A (en) * 2013-03-05 2013-06-12 刘风荣 Chinese medicine composition for treating upper respiratory infection
CN103751515A (en) * 2014-01-06 2014-04-30 崔磊 Pharmaceutical composition for treating upper respiratory infection
CN103751517A (en) * 2014-01-06 2014-04-30 崔磊 Pharmaceutical composition for treating chronic bronchitis

Similar Documents

Publication Publication Date Title
CN102961579A (en) Traditional Chinese medicine composition for treating chronic pharyngitis
CN105012392A (en) Traditional Chinese medicine composition for treating rhinitis and preparation method thereof
CN107961230A (en) A kind of Chinese medicine Warn uterus paste and preparation method thereof
CN104352587A (en) Ointment for treating rhinitis
CN104800660A (en) Traditional Chinese medicine preparation for treating mycoplasma pneumoniae pneumonia and preparation method thereof
CN103751515A (en) Pharmaceutical composition for treating upper respiratory infection
CN103142733B (en) Chinese medicine composition for treating upper respiratory infection
CN101391065B (en) Compound momordica seed pepper soup for treating urgent chronic pelvic inflammatory disease
CN104800817A (en) Medicinal composition for treating dog rhinitis and preparation method thereof
CN107496566A (en) It is a kind of to treat herpes zoster and the Chinese medicine composition and preparation method of bleb sequelae
CN104997945A (en) Traditional Chinese medicine for treating urocystitis
CN104288483A (en) Medicament for treating upper respiratory infection
CN104225412A (en) Traditional Chinese medicine for treating upper respiratory infection
CN106620544A (en) Medicine for treating schizophrenia and preparation method of medicine
CN105168847A (en) Traditional Chinese medicine for treating helicobacter pylori infected peptic ulcer
CN105147909A (en) Chinese herb decoction for treating meningitis and preparation method thereof
CN105343272A (en) Medicine for treating miliaria and preparation method thereof
CN105106727A (en) Traditional Chinese medicine composition for treating liver-fire attacking lung type hemoptysis
CN104587382A (en) Traditional Chinese medicine drop solution for treating rhinitis, as well as preparation method thereof
CN104922526A (en) Traditional Chinese medicine for treating cystolith
CN105749138A (en) Traditional Chinese medicinal dropping liquid for treating rhinitis, and preparation method thereof
CN103638233A (en) Traditional Chinese medicine composition for treating stomach fire up-flaming type periodontitis
CN104983866A (en) Traditional Chinese medicine decoction for treating children cough and asthma
CN104587071A (en) Traditional Chinese medicament for treating infantile blood-heat allergic purpura
CN102872269B (en) Traditional Chinese medicine composition for treating infantile acute tonsillitis

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20150121

RJ01 Rejection of invention patent application after publication