CN104288393A - Traditional Chinese medicine for treating urticaria - Google Patents

Traditional Chinese medicine for treating urticaria Download PDF

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Publication number
CN104288393A
CN104288393A CN201410646905.6A CN201410646905A CN104288393A CN 104288393 A CN104288393 A CN 104288393A CN 201410646905 A CN201410646905 A CN 201410646905A CN 104288393 A CN104288393 A CN 104288393A
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China
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parts
chinese medicine
urticaria
grams
traditional chinese
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Pending
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CN201410646905.6A
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Chinese (zh)
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田丽华
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Individual
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Priority to CN201410646905.6A priority Critical patent/CN104288393A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage

Abstract

The invention relates to a traditional Chinese medicine for treating urticaria. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 6 parts of fineleaf schizonepeta herb, 6 parts of stiff silkworm, 3 parts of periostracum cicadae, 9 parts of fructus kochiae, 9 parts of figwort, 3 parts of giant typhonium rhizome, 6 parts of lithospermum, and 9 parts of forsythia suspensa. Clinical trials prove that the traditional Chinese medicine disclosed by the invention can safely and effectively treat the urticaria.

Description

A kind of Chinese medicine being used for the treatment of urticaria
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of urticaria.
Background technology
definition
Urticaria (urticaria) is commonly called as rubella wheal, is the one limit office property edema reaction because skin, the expansion of mucosa thin vessels and permeability increase and occur.The rubella wheal infringement do not waited sized by clinical manifestation, suddenly occurs, prompt resolution, acute pruritus, does not stay any vestige more.
Urticaria is allergic skin disease, and stadium is no more than 1 month person for acute urticaria, stadium more than 1 month or recurrent exerbation person claim chronic urticaria.Chinese medicine is referred to as rubella.Abnormal with pruritus, skin occurs welt that is different, that differ in size is primary symptom, dermatograph test is positive, without change o f skin colour after disappearing.How to attack by outside ailment said due to cold or exposure, hold back in skin, accumulate in blood system, or because causing gastrointestinal accumulated heat addicted to food greasy and surfeit flavour, fish and shrimp and so on, interiorly can not letting out, can not declare outward, strongly fragrantly to fall ill in skin
Medical material present Research involved in the present invention is as follows:
Herba Schizonepetae [source] this product is the dry aerial parts of labiate Herba Schizonepetae Schizonepeta tenuifolia Briq..Summer, season in autumn two, the flowers are in blossom to top, fringe green time tap, removing impurity, dry.[nature and flavor] are pungent, tepor.[return through] returns lung, Liver Channel.[function cures mainly] induces sweat loose wind, rash.For flu, headache, measles, rubella, skin infection from the beginning of.Parch to black treating hematochezia, metrorrhagia, puerperal blood faints.[usage and dosage] 4.5 ~ 9g.
Bombyx Batryticatus [source] this product is that the larva in Bombycidae insecticide silkworm Bombyx mori Linnaeus. 4 ~ 5 age infects (or artificial vaccination) muscardine Beauveria bassiana(Bals.) Vuillant and lethal larva dry body.Produce more than spring, autumn, the silkworm died of illness by infection muscardine is dry.[nature and flavor] are salty, pungent, flat.[return through] returns liver, lung, stomach warp.[function cures mainly] expelling wind for relieving convulsion, dissipating phlegm and resolving masses.For convulsion with spasms, laryngopharynx swelling and pain, skin pruritus, submandibular lymph nodes is scorching, facial paralysis.[usage and dosage] 5 ~ 9g.
Exuviae shell when Periostracum Cicadae [source] this product is the larva emergence of cicada Cryptotympana atrata Fabr. Cryptotympana pustulata Fabricius.Summer, Qiu Erji collect, and removing silt, dries.[nature and flavor] are sweet, cold.[return through] returns lung, Liver Channel.[function cures mainly] falls apart wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.[usage and dosage] 3 ~ 6g.
The Fructus Kochiae [source] this product is the dry mature fruit of chenopod Fructus Kochiae Kochia scoparia (L.) Schrad..To gather during fruit maturation in autumn plant, dry, lay fruit, removing impurity.[nature and flavor] are pungent, bitter, cold.[return through] returns kidney, urinary bladder channel.[function cures mainly] clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.For difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.[usage and dosage] 9 ~ 15g.
Radix Scrophulariae [source] this product is the dry root of goatweed Radix Scrophulariae Scrophularia ningpoensis Hemsl..Excavate when winter, stem and leaf was withered.Removing rhizome, plumelet, fibrous root and silt, shine or be dried to half-dried, stacking 3 ~ 6 days, repeatedly for several times to dry.[nature and flavor] are sweet, bitter, salty, are slightly cold.[return through] returns lung, stomach, kidney channel.[function cures mainly] removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.[usage and dosage] 9 ~ 15g.[attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.
 
Rhizoma Typhonii [source] this product is the dry tuber of aroid Herba Typhonii gigantei Typhonium giganteum Engl..Autumn excavates, and removing fibrous root and crust, dry.[nature and flavor] are pungent, temperature; Poisonous.[return through] returns stomach, Liver Channel.[function cures mainly] dispels the wind expectorant, and arresting convulsion is jerked, detoxicating and resolving stagnation of pathogens pain relieving.Stop up for middle wind-phlegm, facial hemiparalysis, language is puckery stuttering, and syncope due to accumulation of phlegm is had a headache, migraine and general headache, sore throat pharyngalgia, tetanus; External treatment scrofula sucutaneous nodule, venom.[usage and dosage] generally concocts rear use, 3 ~ 6g.
Radix Arnebiae (Radix Lithospermi) [source] this product is the dry root of comfrey lithospermum euchromum Royle Arnebia euchroma (Royle) Johnst., Radix Arnebiae (Radix Lithospermi) Lithospermum erythrorhizon Sieb. et Zucc. or arnebia guttata Bunge Arnebia guttata Bunge.Spring, Qiu Erji excavate, removing silt, dry.[nature and flavor] are sweet, salty, cold.[return through] GUIXIN, Liver Channel.[function cures mainly] removing heat from blood, invigorates blood circulation, removing toxic substances rash.Contain for heat in blood poison, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.[usage and dosage] 5 ~ 9g.
Fructus Forsythiae [source] this product is the dry fruit of Oleaceae plants Fructus Forsythiae Forsythia suspensa (Thunb.) Vahl.Gather during fruit in autumn first ripe still band green, removing impurity, cooks, dries, and practises title " green grass or young crops sticks up "; Gather when fruit is well-done, dry, removing impurity, practises and claims " always sticking up ".[nature and flavor] are bitter, are slightly cold.[return through] returns lung, the heart, small intestine meridian.[function cures mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.[usage and dosage] 6 ~ 15g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of urticaria, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing urticaria.
In order to achieve the above object, the present invention is by the following technical solutions:
Be used for the treatment of a Chinese medicine for urticaria, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Schizonepetae 6 parts, Bombyx Batryticatus 6 parts, Periostracum Cicadae 3 parts, the Fructus Kochiae 9 parts, Radix Scrophulariae 9 parts, Rhizoma Typhonii 3 parts, Radix Arnebiae (Radix Lithospermi) 6 parts, Fructus Forsythiae 9 parts.
Inventor thinks that urticaria is attacked by outside ailment said due to cold or exposure, holds back in skin, accumulates in blood system, or because causing gastrointestinal accumulated heat addicted to food greasy and surfeit flavour, fish and shrimp and so on, interiorly can not letting out, can not declare outward, and strongly fragrant morbidity in skin belongs to heat in blood and to hold concurrently wind, and controlling to purify the blood dispels the wind.Therefore assembly is our.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects outpatient service and urticaria patient 102 example of being in hospital altogether between in August, 2010 ~ in February, 2013, be divided into treatment group 52 example and matched group 50 example at random, treatment group man 26 example, female 26 example, 20 ~ 45 years old age, 38.6 years old mean age, the course of disease 1 ~ 3 year; Matched group man 24 example, female 26 example, 22 ~ 45 years old age, 37.9 years old mean age, the course of disease 1 ~ 3 year.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
2, Symptoms Assessment and curative effect determinate standard
2nd week, the 4th week, the 8th week and drug withdrawal, after 4 weeks, are marked, in table 1 to two groups of patients symptomatic and sign respectively by 4 grades of point systems before treatment and after treatment.Therapeutic index: integration × 100% before (treat front integration one and treat rear integration)/treatment.Therapeutic index >=90% is recovery from illness; 90% > therapeutic index >=60% is effective; 60% > therapeutic index >=30% is effective; Therapeutic index <30% is invalid.Effective percentage (%)=(recovery from illness number of cases+effective number of cases)/total number of cases × 100%.
3, statistical method adopts SPSS18.0 statistical software to carry out statistical analysis.Enumeration data represents with rate, carries out x 2inspection; Be that difference has statistical significance with P<0.05.
4, Therapeutic Method
The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.
The oral loratadine of matched group (the accurate word H10970410 of Shanghai Schering Plough pharmaceutical Co. Ltd traditional Chinese medicines), takes according to its description.
5, therapeutic outcome is in table 1 and table 2.
Visible, the medicine that the present invention obtains can safe and effective treatment urticaria, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Herba Schizonepetae 6 grams, Bombyx Batryticatus 6 grams, Periostracum Cicadae 3 grams, the Fructus Kochiae 9 grams, Radix Scrophulariae 9 grams, Rhizoma Typhonii 3 grams, Radix Arnebiae (Radix Lithospermi) 6 grams, Fructus Forsythiae 9 grams.Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of urticaria.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: Herba Schizonepetae 6 grams, Bombyx Batryticatus 6 grams, Periostracum Cicadae 3 grams, the Fructus Kochiae 9 grams, Radix Scrophulariae 9 grams, Rhizoma Typhonii 3 grams, Radix Arnebiae (Radix Lithospermi) 6 grams, Fructus Forsythiae 9 grams.Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of urticaria.Oral, daily once.
Specific embodiment 3
Take: Herba Schizonepetae 6 grams, Bombyx Batryticatus 6 grams, Periostracum Cicadae 3 grams, the Fructus Kochiae 9 grams, Radix Scrophulariae 9 grams, Rhizoma Typhonii 3 grams, Radix Arnebiae (Radix Lithospermi) 6 grams, Fructus Forsythiae 9 grams.Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of urticaria.Oral, every bu is taken for twice sooner or later.

Claims (1)

1. be used for the treatment of a Chinese medicine for urticaria, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Schizonepetae 6 parts, Bombyx Batryticatus 6 parts, Periostracum Cicadae 3 parts, the Fructus Kochiae 9 parts, Radix Scrophulariae 9 parts, Rhizoma Typhonii 3 parts, Radix Arnebiae (Radix Lithospermi) 6 parts, Fructus Forsythiae 9 parts.
CN201410646905.6A 2014-11-16 2014-11-16 Traditional Chinese medicine for treating urticaria Pending CN104288393A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101961415A (en) * 2010-09-20 2011-02-02 侯洪领 Decoction for treating chronic urticaria
CN101991702A (en) * 2009-08-25 2011-03-30 王克胜 Traditional Chinese medical oral drug for treating urticaria
CN102370914A (en) * 2011-10-21 2012-03-14 马良玉 Oral Chinese patent medicine pill for treating urticaria

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101991702A (en) * 2009-08-25 2011-03-30 王克胜 Traditional Chinese medical oral drug for treating urticaria
CN101961415A (en) * 2010-09-20 2011-02-02 侯洪领 Decoction for treating chronic urticaria
CN102370914A (en) * 2011-10-21 2012-03-14 马良玉 Oral Chinese patent medicine pill for treating urticaria

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张问渠主编: "《现代著名老中医临床诊治荟萃》", 31 August 1986, 科学技术文献出版社 *

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