CN104288181B - It is a kind of to treat pet because expelling parasite causes paste for not relaxing and preparation method thereof - Google Patents
It is a kind of to treat pet because expelling parasite causes paste for not relaxing and preparation method thereof Download PDFInfo
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- CN104288181B CN104288181B CN201410581533.3A CN201410581533A CN104288181B CN 104288181 B CN104288181 B CN 104288181B CN 201410581533 A CN201410581533 A CN 201410581533A CN 104288181 B CN104288181 B CN 104288181B
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- expelling parasite
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- montmorillonite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Abstract
The present invention, which disclose, a kind of treats pet because expelling parasite causes paste of adverse reaction and preparation method thereof, it is desirable to provide a kind of to release pet because expelling parasite causes the paste to actual bodily harm.It is characterized in that：On the one hand, present invention offer is a kind of treats pet because expelling parasite causes the paste of adverse reaction, is made of following components in parts by weight：1~10 part of silymarin, 1~10 part of vitamin C, 15~35 parts of liver extract, 1 10 parts of bismuth potassium citrate, 0.5~5 part of tributyrin, 5~20 parts of montmorillonite, 0.5~2 part of guar gum, 0.5~2 part of Arabic gum, 0.1~1 part of citric acid, 0.1~1 part of sodium benzoate, 30~70 parts of distilled water.On the other hand, the present invention also provides the preparation method of above-mentioned paste.The invention belongs to animal medicine technical field.
Description
Technical field
Pet is treated because expelling parasite causes the paste that does not relax the present invention relates to a kind of, specifically, is related to one kind and is treated pet
Because expelling parasite causes paste for not relaxing and preparation method thereof, belong to animal medicine technical field.
Background technology
Raising pet becomes a kind of fashion, and the raise competence of raiser also generally improves, particularly in terms of health care.Such as
The expelling parasite knowledge of dog, raiser both know about generally after puppy is weaned just should expelling parasite first, puppy below 6 monthly ages preferably monthly drives
Worm 1 time, adult dogs quarterly expelling parasite 1 time, kind of bitches expelling parasite 1 time before breeding, lactation bitch can be with the expelling parasites at the same time of young dog.And give
The side effect brought during pet parasite expelling, such as vomiting, diarrhea, spiritual depressed, loss of appetite, it is often more anxious, and do not know
What if.
Most of puppy has Enterozoa, is infected by mother through placenta or milk.It is parasitic since the enteric cavity of puppy is thin
Worm relative populations are more, individual is big, cause puppy to lose the appetite, become thin, hypoevolutism；Constipation or diarrhea, abdominal pain, vomiting, abdominal circumference
Increase.Indivedual puppies can trigger enteric intussusception, or rectal prolapse.Severe infections can cause severe complication and dead.When to pet
When feeding anthelmintic, also following injury is brought to pet while expelling parasite：1. to the injury of stomach, cause to produce after dog medicine feed to vomit
Spit phenomenon；2. injury when Enterozoa is dead to enteron aisle, produces toxin, intestinal mucosa is damaged, causes diarrhea, loss of appetite；
3. all anthelmintics all produce toxic side effect to liver, such as Switzerland's vapour bar, main ingredient Nitroscanate, side effect mainly has dizzy, head
Bitterly, dizziness, instability of gait, abdominal distension, diarrhea, Nausea and vomiting etc., generally occur on the 2nd day in medication, disappear within 1 week or so.A small number of diseases
Example has slight jaundice；Worm escapes in Bayer Bitterfeld GmbH, main ingredient：Praziquantel, Pyrantel, Febantel；Zental also known as albendazole, pair are made
With there is the adverse reaction such as mild headache, giddy, nausea,vomiting,diarrhea, dry, weak；Pu Nadu ingots, main ingredient：Praziquantel, Ah
Parbendazole.Praziquantel side effect has apocleisis, vomiting or diarrhea etc..
The anthelmintic kind of pet is more and more at present, but solution anthelmintic brings the product of the side effect of pet almost
No.
The content of the invention
Pet is treated because expelling parasite causes the paste that does not relax it is an object of the present invention to provide a kind of.
It is another object of the present invention to provide the preparation method of above-mentioned paste.
It is in order to solve the above technical problems, the technical scheme is that such：
On the one hand, it is a kind of to treat pet because expelling parasite causes the paste that does not relax, it is made of following components in parts by weight：By following
The component composition of parts by weight：1~10 part of silymarin, 1~10 part of vitamin C, 15~35 parts of liver extract, bismuth potassium citrate 1-10
Part, 0.5~5 part of tributyrin, 5~20 parts of montmorillonite, 0.5~2 part of guar gum, 0.5~2 part of Arabic gum, citric acid 0.1
~1 part, 0.1~1 part of sodium benzoate, 30~70 parts of distilled water.
Further, above-mentioned treatment pet causes the paste that does not relax because of expelling parasite, is made of following components in parts by weight：By
Following components in parts by weight forms 2~8 parts of silymarin, Catergen~18 part, 20~30 parts of liver extract, bismuth potassium citrate 2-8
Part, 0.8~3 part of tributyrin, 8~18 parts of montmorillonite, 0.8~1.8 part of guar gum, 0.8~1.8 part of Arabic gum, lemon
0.2~0.8 part of acid, 0.2~0.8 part of sodium benzoate, 35~65 parts of distilled water.
On the other hand, pet is treated because expelling parasite causes the preparation method of paste do not relaxed the present invention also provides a kind of, successively
Comprise the following steps：1) each component is weighed by following weight parts：1~10 part of silymarin, 1~10 part of vitamin C, liver extract
15~35 parts, 1-10 parts of bismuth potassium citrate, 0.5~5 part of tributyrin, 5~20 parts of montmorillonite, 0.5~2 part of guar gum, I
Primary 0.5~2 part of glue, 0.1~1 part of citric acid, 0.1~1 part of sodium benzoate, 30~70 parts of distilled water；
2) sodium benzoate is added in the distilled water weighed to step 1), guar gum and Arabic gum is added after dissolving, placed,
Allow it to be swollen, obtain mixture A；
3) silymarin, vitamin C, bismuth potassium citrate, tributyrin, montmorillonite, liver are sequentially added into mixture A again
Medicinal extract, and stir evenly, obtain mixture B；
4) most backward mixture B adds citric acid, homogenizes after stirring.
The present invention is after using above-mentioned paste and preparation method thereof, compared with prior art, the invention has the advantages that：
1st, silymarin, is known as " natural hepatoprotective agent ", protects liver cell to be encroached on from toxicant, especially alcohol
And environmental contaminants (pesticide, heavy metal etc.) invasion infringement liver；Anti-oxidation function with strength, can protect liver cell to exempt from
Destroyed by free radical, effect outclass vitamin E；Promote the synthesis of protein, accelerate to manufacture new liver cell, or order by
The liver cell self-healing of damage.
2nd, vitamin C, promotes organic matter or poisonous substance hydroxylation removing toxic substances, vitamin C to lift the activity of mixed-function oxidase,
Strengthen the removing toxic substances (hydroxylation) of medicine or poisonous substance.
3rd, tributyrin, there is provided protection of intestinal mucosal barrier cells energy source, promotes epithelial cell proliferation and differentiation, effectively repair intestines
Mucosa injury, protects intestinal mucosa comprehensively.
4th, montmorillonite, montmorillonite are effective to diarrhea caused by the various causes of disease, and can increase the mucus quantity and improve viscous
The cohesive force and elasticity of liquid Quality advance mucus, so as to play protection and repair to gastrointestinal mucosal.
5th, bismuth potassium citrate：The protective layer that dispersivity is formed in the sour environment of stomach is covered on ulcer surface, prevention hydrochloric acid in gastric juice,
The invasion and attack of enzyme and food to ulcer.This product can also reduce pepsin activity, increase mucin secretion, promote mucous membrane release forefront
Parathyrine, so as to protect stomach lining.
The effect of the drug regimens such as above-mentioned silymarin, vitamin C, tributyrin, montmorillonite, bismuth potassium citrate is：It is slow
Solution expelling parasite brings the stress reaction of pet, protection and reparation liver, and antidiarrheal is rapid to recover impaired alimentary canal, recovers appetite, raising
The resistance of pet.
In short, the treatment pet of the present invention disclosure satisfy that the demand of pet lovers because expelling parasite causes the paste that does not relax, rescue
Pet pain.
Embodiment
With reference to specific embodiment, the claim of the present invention is described in further detail, but is not formed to this
Any restrictions of invention, the modification of anyone limited number of time made in the range of application claims still will in the right of the present invention
Ask within protection domain.
Embodiment 1
The a kind of of the present invention treats pet because expelling parasite causes the paste that does not relax, is made of following components in parts by weight：Fine grinding
10 parts of silibin, 1 part of vitamin C, 15 parts of liver extract, 1 part of bismuth potassium citrate, 0.5 part of tributyrin, 5 parts of montmorillonite, guar gum 2
Part, 0.5 part of Arabic gum, 1 part of citric acid, 0.1 part of sodium benzoate, 70 parts of distilled water.
Embodiment 2
The treatment pet of the present invention forms silymarin 1 because expelling parasite causes the paste that does not relax by following components in parts by weight
Part, 10 parts of vitamin C, 35 parts of liver extract, 10 parts of bismuth potassium citrate, 5 parts of tributyrin, 0 part of montmorillonite 2,2 parts of guar gum, Ah
Draw primary 0.5 part of glue, 0.1 part of citric acid, 1 part of sodium benzoate, 30 parts of distilled water.
Embodiment 3
The treatment pet of the present invention is made of because expelling parasite causes the paste that does not relax following components in parts by weight：Silymarin 5
Part, 5 parts of vitamin C, 25 parts of liver extract, 5 parts of bismuth potassium citrate, 2 parts of tributyrin, 10 parts of montmorillonite, 1 part of guar gum, I
Primary 1 part of glue, 0.5 part of citric acid, 0.5 part of sodium benzoate, 45 parts of distilled water.
Embodiment 4
The present invention also have it is a kind of treat pet because expelling parasite causes the paste that does not relax, be made of following components in parts by weight：Water
Fly 2 parts of silibin, 8 parts of vitamin C, 20 parts of liver extract, 1 part of bismuth potassium citrate, 1 part of tributyrin, 15 parts of montmorillonite, guar gum
0.8 part, 1.2 parts of Arabic gum, 0.4 part of citric acid, 0.7 part of sodium benzoate, 40 parts of distilled water.
Embodiment 5
Another treatment pet of the present invention is made of because expelling parasite causes the paste that does not relax following components in parts by weight：Water
Fly 8 parts of silibin, Catergen part, 30 parts of liver extract, 3 parts of bismuth potassium citrate, 4 parts of tributyrin, 8 parts of montmorillonite, guar gum 1.5
Part, 0.5 part of Arabic gum, 0.6 part of citric acid, 0.8 part of sodium benzoate, 50 parts of distilled water.
In embodiment 1 to 5 it is a kind of treat the paste that pet causes not relax because of expelling parasite preparation method be：Include successively following
Step：1) each component is weighed according to any embodiment in embodiment 1 to 5：2) add in the distilled water weighed to step 1)
Enter sodium benzoate, guar gum and Arabic gum are added after dissolving, place, allow it to be swollen, obtain mixture A；3) again to mixture A
In sequentially add silymarin, vitamin C, bismuth potassium citrate, tributyrin, montmorillonite, liver extract, and stir evenly, obtain
Mixture B；4) most backward mixture B adds citric acid, homogenizes after stirring.
When specifically used：Used when 4-6 is small after expelling parasite, direct feeding or or make an addition to grain, drinking-water in, daily two
Secondary, each 10ml, is used in conjunction five days.
Where better illustrating advantages of the present invention, the use case that the present invention is given below is explained.
Case 1：
Suffer from dog：Golden hair female age：2 months weight：10.0 (kilograms)
Symptom：Suffer from diarrhea second day of expelling parasite.
Diagnosis：Stress reaction after expelling parasite.
Therapeutic scheme：Liver protection, antidiarrheal, protects intestinal mucosa, feeds expelling parasite Triratna, food is mixed together with dog grain, 2 times a day, often
Secondary 10 milliliters, antidiarrheal, the state of mind were recovered normal at the 3rd day in second day.
Case 2
Suffer from dog：Sa Moye, male, 2 first quarter moons
Symptom：Off color, suffers from diarrhea a little, and yesterday also vomitted later to anthelmintic.
Analyze the cause of disease：Expelling parasite is reacted
Therapeutic scheme：Liver protection, antidiarrheal, protects intestinal mucosa, feeds expelling parasite Triratna, food is mixed together with dog grain, 2 times a day, often
Secondary 10 milliliters, just do not have loose bowels within second day, while add and feed probiotics, just vivaciously dap within the 3rd day.
Case 3
Suffer from dog：Golden hair, female, 8 months 1 years old
Symptom：Suffer from diarrhea and vomiting after having eaten anthelmintic, drawing must be than more serious.
Analyze the cause of disease：Expelling parasite is reacted
Therapeutic scheme：Antidiarrheal, liver protection, protects gastrointestinal mucosa, feeds expelling parasite Triratna, adds food to dog, 2 times a day, every time 10
Milliliter, does not just have loose bowels, while supplement drinking-water for second day.Action recovers normal.
Case 4
Suffer from dog：Ha Shiqi, male, three months
Symptom：Spirit is slightly depressed after expelling parasite, slight vomiting, diarrhoea.
Analyze the cause of disease：Expelling parasite is reacted
Therapeutic scheme：Antidiarrheal, liver protection, protects gastrointestinal mucosa, feeds expelling parasite Triratna, adds food to dog, 2 times a day, every time 10
Milliliter, does not just suffer from diarrhea, just refreshes within the 3rd day for substantially second day.
Claims (3)
1. a kind of treat pet because expelling parasite causes the paste that does not relax, it is characterised in that is made of following components in parts by weight：Fine grinding
1~10 part of silibin, 1~10 part of vitamin C, 15~35 parts of liver extract, 1-10 parts of bismuth potassium citrate, 0.5~5 part of tributyrin,
5~20 parts of montmorillonite, 0.5~2 part of guar gum, 0.5~2 part of Arabic gum, 0.1~1 part of citric acid, sodium benzoate 0.1~1
Part, 30~70 parts of distilled water.
2. treatment pet according to claim 1 causes the paste that does not relax because of expelling parasite, it is characterised in that by following weight parts
Component composition：2~8 parts of silymarin, Catergen~18 part, 20~30 parts of liver extract, 2-8 parts of bismuth potassium citrate, butyric acid is sweet
0.8~3 part of grease, 8~18 parts of montmorillonite, 0.8~1.8 part of guar gum, 0.8~1.8 part of Arabic gum, citric acid 0.2~0.8
Part, 0.2~0.8 part of sodium benzoate, 35~65 parts of distilled water.
3. a kind of any treatment pet of claim 1 or 2 causes the preparation method of paste do not relaxed, its feature because of expelling parasite
It is, comprises the following steps successively：
1) parts by weight as described in claim 1 or claim 2 weigh each component；
2) sodium benzoate is added in the distilled water weighed to step 1), guar gum and Arabic gum is added after dissolving, placed, allow it
Swelling, obtains mixture A；
3) silymarin, vitamin C, bismuth potassium citrate, tributyrin, montmorillonite, liver leaching are sequentially added into mixture A again
Cream, and stir evenly, obtain mixture B；
4) most backward mixture B adds citric acid, homogenizes after stirring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410581533.3A CN104288181B (en) | 2014-10-27 | 2014-10-27 | It is a kind of to treat pet because expelling parasite causes paste for not relaxing and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410581533.3A CN104288181B (en) | 2014-10-27 | 2014-10-27 | It is a kind of to treat pet because expelling parasite causes paste for not relaxing and preparation method thereof |
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| Publication Number | Publication Date |
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| CN104288181A CN104288181A (en) | 2015-01-21 |
| CN104288181B true CN104288181B (en) | 2018-05-04 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109170305A (en) * | 2018-08-03 | 2019-01-11 | 深圳市红瑞生物科技有限公司 | Improve the prescription cream and preparation method thereof of pet liver function |
| CN111202164B (en) * | 2019-06-13 | 2023-10-13 | 杭州海渤源生物科技有限公司 | Pet insect-repellent composite soft capsule and preparation method thereof |
| US20220411994A1 (en) * | 2021-06-29 | 2022-12-29 | Microban Products Company | Composition and method for odor reduction and bacterial control on a textile |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1158724A (en) * | 1996-10-30 | 1997-09-10 | 王玉万 | Veterinary antiparasitic lincture contg. avermectin or invermectin |
| CN1686519A (en) * | 2005-03-23 | 2005-10-26 | 张帆 | Medicinal composition for preventing alcoholic liver damage |
| CN102078371A (en) * | 2009-11-27 | 2011-06-01 | 天津瑞普生物技术股份有限公司 | Pharmaceutical composition for preventing and treating chicken proventriculitis |
-
2014
- 2014-10-27 CN CN201410581533.3A patent/CN104288181B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1158724A (en) * | 1996-10-30 | 1997-09-10 | 王玉万 | Veterinary antiparasitic lincture contg. avermectin or invermectin |
| CN1686519A (en) * | 2005-03-23 | 2005-10-26 | 张帆 | Medicinal composition for preventing alcoholic liver damage |
| CN102078371A (en) * | 2009-11-27 | 2011-06-01 | 天津瑞普生物技术股份有限公司 | Pharmaceutical composition for preventing and treating chicken proventriculitis |
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