CN104274424A - Plant empty capsule and manufacturing method thereof - Google Patents
Plant empty capsule and manufacturing method thereof Download PDFInfo
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- CN104274424A CN104274424A CN201410450102.3A CN201410450102A CN104274424A CN 104274424 A CN104274424 A CN 104274424A CN 201410450102 A CN201410450102 A CN 201410450102A CN 104274424 A CN104274424 A CN 104274424A
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- capsule
- glue
- plant
- carrageenan
- cellulose
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Abstract
The invention provides a plant empty capsule with a good moulding effect, high surface smoothness and good elasticity and a manufacturing method thereof. The plant empty capsule comprises 88-90wt% of complex gum, 1-3wt% of potassium chloride, 0.3-0.5wt% of humectant, 0-0.2wt% of polysaccharide, 3-5wt% of medical glycerinum, 1-3wt% of titanium dioxide and 0.2-0.3wt% of food colourant, wherein the complex gum comprises carrageenan, plant cellulose and sodium carboxymethylcellulose. The plant empty capsule is low in water content, is especially applicable to being filled with medicines which have strong hygroscopicity and are sensitive to moisture, has the advantages of wide applicability, no crosslinking reaction and high stability and is preservative-free, and microorganisms can hardly grow on the empty capsule; and meanwhile, the plant empty capsule is hardly crisp or broken at a low temperature and is still stable in capsule shell character at a high temperature.
Description
Technical field
The present invention relates to a kind of capsule and method for making thereof, especially a kind of plant hollow capsule and method for making thereof.
Background technology
Existing Capsules molding effect is poor, the shortcoming such as surface smoothness and poor flexibility.
Summary of the invention
The invention provides plant hollow capsule and the method for making thereof of a kind of good forming effect, surface smoothness and good springiness.
Realize the plant hollow capsule of one of the object of the invention, comprise compound gel 88 ~ 90wt%, potassium chloride 1 ~ 3wt%, wetting agent 0.3 ~ 0.5wt%, polysaccharide 0 ~ 0.2wt%, medicinal glycerin 3 ~ 5wt%, titanium dioxide 1 ~ 3wt%, food coloring 0.2 ~ 0.3wt%;
Described compound gel comprises carrageenan, plant cellulose and sodium carboxymethyl cellulose.
The weight ratio of described carrageenan, plant cellulose and sodium carboxymethyl cellulose is: 12: 82: 6.
Realize the method for making of the plant hollow capsule of the object of the invention two, comprise the steps:
(1) colloidal sol, by carrageenan, plant cellulose and sodium carboxymethyl cellulose under rapid mixing conditions, little by little drops into plastic powder in the distilled water of 90 ~ 95 degrees Celsius, abundant mix and blend 60 minutes,, after keeping the temperature response time of 60 minutes, make to dissolve uniformly glue; Add various adjuvant again, and stir, glue temperature is down to 50 degrees Celsius, continue insulated and stirred 5 hours, formed and dip in gum forming solution, namely available capsule die carries out dipping in glue base.
In described step (1), the weight ratio of carrageenan, plant cellulose and sodium carboxymethyl cellulose is: 12: 82: 6.
(2) dip in glue base: with capsule die, immersed in glue by film bar and be stained with glue capsule blank, the film bar first choosing appropriate gauge is fixed in template, lubricates with appropriate mould oil.Steadily held by film bar, immersed downwards in glue upper end, treat glue whole submergence film bar about 2 ~ 3 seconds, namely slowly template mentioned, leave glue liquid surface, then template dug, upset makes it cool for several times, dips in glue speed and is generally advisable with 5 ~ 6 plates per minute;
(3) dry: capsule uses the hot-air dry of flowing, and baking temperature remains on 32 ~ 35 degrees Celsius, and humidity remains on 50-55 degree Celsius, dry 1.5 ~ 2 hours, the final water content of blastaea was 6 ~ 8wt%;
(4) pull out shell and cut: clamp with special capsule and blastaea is pulled up, blastaea capsule cutting machine is cut into the length of regulation;
(5) inspection and packaging is arranged: be placed in by Manufactured Capsules on special workbench, table top is glass, fills daylight lamp below, table top checks, reject defective work, by upper and lower for capsule two joint cover and, splendid attire is in hermetic container, and storage is located with cool place drying.
The beneficial effect of plant hollow capsule of the present invention and method for making thereof is as follows:
Plant hollow capsule of the present invention, water content is low, is applicable to very much the filling of the strong and medicine to moisture-sensitive of hygroscopicity, have the suitability wide, without cross-linking reaction risk and the high advantage of stability, preservative free, plant capsule not easily grows microorganism; Friability hardly under cryogenic, under high temperature, softgel shell character is still stablized.
Carrageenan is adopted to be a kind of water soluble polysaccharide extracted from red algae, there is the characteristics such as thickening, gel, film forming and stable dispersion, particularly when carrageenan and sodium carboxymethyl cellulose composite time, cooperative effect is best, tenacity and the elasticity of capsule can be increased, therefore, one of carrageenan important raw materials for production just becoming vegetable glue softgel shell.
Use plant cellulose, intensity, flexibility are very stable, substantially without hygroscopic effect, have the performances such as good film forming, dispersion, thickening, bonding, water conservation, play the effect of skeleton in capsule shells.
Detailed description of the invention
Plant hollow capsule of the present invention, comprises compound gel 88 ~ 90wt%, potassium chloride 1 ~ 3wt%, wetting agent 0.3 ~ 0.5wt%, polysaccharide 0 ~ 0.2wt%, medicinal glycerin 3 ~ 5wt%, titanium dioxide 1 ~ 3wt%, food coloring 0.2 ~ 0.3wt%;
Described compound gel comprises carrageenan, plant cellulose and sodium carboxymethyl cellulose.
The weight ratio of described carrageenan, plant cellulose and sodium carboxymethyl cellulose is: 12: 82: 6.
The method for making of plant hollow capsule of the present invention, comprises the steps:
(1) colloidal sol, by carrageenan, plant cellulose and sodium carboxymethyl cellulose under rapid mixing conditions, little by little plastic powder is dropped in the distilled water of 50 ~ 60 degrees Celsius, mix and blend 5 minutes, then move in interlayer steam cooker, glue is heated to 85 degrees Celsius, and fully stirs, after keeping the temperature response time of 20 minutes, make to dissolve uniformly glue; Add various adjuvant again, and stir, glue temperature is down to 50 degrees Celsius, continue insulated and stirred 5 hours, formed and dip in gum forming solution, namely available capsule die carries out dipping in glue base.
In described step (1), the weight ratio of carrageenan, plant cellulose and sodium carboxymethyl cellulose is: 12: 82: 6.
(2) dip in glue base: with capsule die, immersed in glue by film bar and be stained with glue capsule blank, the film bar first choosing appropriate gauge is fixed in template, lubricates with appropriate mould oil.Steadily held by film bar, immersed downwards in glue upper end, treat glue whole submergence film bar about 2 ~ 3 seconds, namely slowly template mentioned, leave glue liquid surface, then template dug, upset makes it cool for several times, dips in glue speed and is generally advisable with 5 ~ 6 plates per minute;
(3) dry: capsule uses the hot-air dry of flowing, and baking temperature remains on 32 ~ 35 degrees Celsius, humidity 50-55 degree Celsius of drying 1.5 ~ 2 hours, the final water content of blastaea is 6 ~ 8wt%;
(4) pull out shell and cut: clamp with special capsule and blastaea is pulled up, blastaea capsule cutting machine is cut into the length of regulation;
(5) inspection and packaging is arranged: be placed in by Manufactured Capsules on special workbench, table top is glass, fills daylight lamp below, table top checks, reject defective work, by upper and lower for capsule two joint cover and, splendid attire is in hermetic container, and storage is located with cool place drying.
Embodiment recited above is only be described the preferred embodiment of the present invention; not scope of the present invention is limited; do not departing under the present invention designs spiritual prerequisite; the various distortion that the common engineers and technicians in this area make technical solution of the present invention and improvement, all should fall in protection domain that claims of the present invention determine.
Claims (5)
1. a plant hollow capsule, is characterized in that: comprise compound gel 88 ~ 90wt%, potassium chloride 1 ~ 3wt%, wetting agent 0.3 ~ 0.5wt%, polysaccharide 0 ~ 0.2wt%, medicinal glycerin 3 ~ 5wt%, titanium dioxide 1 ~ 3wt%, food coloring 0.2 ~ 0.3wt%;
Described compound gel comprises carrageenan, plant cellulose and sodium carboxymethyl cellulose.
2. plant hollow capsule according to claim 1, is characterized in that: the weight ratio of described carrageenan, plant cellulose and sodium carboxymethyl cellulose is: 12: 82: 6.
3. a method for making for plant hollow capsule, comprises the steps:
(1) colloidal sol, by carrageenan, plant cellulose and sodium carboxymethyl cellulose under rapid mixing conditions, little by little plastic powder is dropped in the distilled water of 90-95 degree Celsius, abundant mix and blend 60 minutes, after keeping the temperature response time of 60 minutes, make to dissolve uniformly glue; Add various adjuvant again, and stir, glue temperature is down to 50 degrees Celsius, continue insulated and stirred 5 hours, formed and dip in gum forming solution, namely available capsule die carries out dipping in glue base.
4. the method for making of plant hollow capsule according to claim 3, is characterized in that: in described step (1), and the weight ratio of carrageenan, plant cellulose and sodium carboxymethyl cellulose is: 12: 82: 6.
5. the method for making of plant hollow capsule according to claim 3, is characterized in that: also comprise the steps:
(2) dip in glue base: with capsule die, immersed in glue by film bar and be stained with glue capsule blank, the film bar first choosing appropriate gauge is fixed in template, lubricates with appropriate mould oil.Steadily held by film bar, immersed downwards in glue upper end, treat glue whole submergence film bar about 2 ~ 3 seconds, namely slowly template mentioned, leave glue liquid surface, then template dug, upset makes it cool for several times, dips in glue speed and is generally advisable with 5 ~ 6 plates per minute;
(3) dry: capsule uses the hot-air dry of flowing, and baking temperature remains on 32 ~ 35 degrees Celsius, and humidity remains on 50-55 degree Celsius, dry 1.5 ~ 2 hours, the final water content of blastaea was 6 ~ 8wt%;
(4) pull out shell and cut: clamp with special capsule and blastaea is pulled up, blastaea capsule cutting machine is cut into the length of regulation;
(5) inspection and packaging is arranged: be placed in by Manufactured Capsules on special workbench, table top is glass, fills daylight lamp below, table top checks, reject defective work, by upper and lower for capsule two joint cover and, splendid attire is in hermetic container, and storage is located with cool place drying.
Priority Applications (1)
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CN201410450102.3A CN104274424A (en) | 2014-09-05 | 2014-09-05 | Plant empty capsule and manufacturing method thereof |
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CN201410450102.3A CN104274424A (en) | 2014-09-05 | 2014-09-05 | Plant empty capsule and manufacturing method thereof |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104758271A (en) * | 2015-03-16 | 2015-07-08 | 中华生物科技有限公司 | Plant vacant capsule compounded from cellulose gum and red alga KAPPA gum and preparation method thereof |
CN104799286A (en) * | 2015-04-30 | 2015-07-29 | 南京中生生物科技有限公司 | Composition for improving immunity and preparation method of composition |
CN113507832A (en) * | 2018-11-06 | 2021-10-15 | 德罗纳斯德公司 | Capsule planting system and method |
CN115039872A (en) * | 2022-07-22 | 2022-09-13 | 青岛海之林生物科技开发有限公司 | Plant-based temperature-sensitive gel skin jelly and preparation method thereof |
CN115322449A (en) * | 2022-09-16 | 2022-11-11 | 东莞东美食品有限公司 | Preparation process of modified starch plant capsule |
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CN1292261A (en) * | 1999-09-28 | 2001-04-25 | 上海大众凌伟生化股份有限公司 | Plant hard capsule and its production process |
CN101069677A (en) * | 2007-06-15 | 2007-11-14 | 潮州市强基制药厂 | Pullulan polysaccharide hollow hard capasule and its preparing method |
CN101439028A (en) * | 2009-01-06 | 2009-05-27 | 湖州展望天明药业有限公司 | Hypromellose composition and application thereof in preparing plant base medicinal capsule |
CN103100091A (en) * | 2013-01-04 | 2013-05-15 | 山东大学(威海) | Compound seaweed gum and application thereof to capsule preparation |
CN103301086A (en) * | 2013-06-05 | 2013-09-18 | 绍兴康可胶囊有限公司 | Plant cellulose hard empty capsule preparation method |
-
2014
- 2014-09-05 CN CN201410450102.3A patent/CN104274424A/en active Pending
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CN1292261A (en) * | 1999-09-28 | 2001-04-25 | 上海大众凌伟生化股份有限公司 | Plant hard capsule and its production process |
CN101069677A (en) * | 2007-06-15 | 2007-11-14 | 潮州市强基制药厂 | Pullulan polysaccharide hollow hard capasule and its preparing method |
CN101439028A (en) * | 2009-01-06 | 2009-05-27 | 湖州展望天明药业有限公司 | Hypromellose composition and application thereof in preparing plant base medicinal capsule |
CN103100091A (en) * | 2013-01-04 | 2013-05-15 | 山东大学(威海) | Compound seaweed gum and application thereof to capsule preparation |
CN103301086A (en) * | 2013-06-05 | 2013-09-18 | 绍兴康可胶囊有限公司 | Plant cellulose hard empty capsule preparation method |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104758271A (en) * | 2015-03-16 | 2015-07-08 | 中华生物科技有限公司 | Plant vacant capsule compounded from cellulose gum and red alga KAPPA gum and preparation method thereof |
CN104799286A (en) * | 2015-04-30 | 2015-07-29 | 南京中生生物科技有限公司 | Composition for improving immunity and preparation method of composition |
CN113507832A (en) * | 2018-11-06 | 2021-10-15 | 德罗纳斯德公司 | Capsule planting system and method |
CN115039872A (en) * | 2022-07-22 | 2022-09-13 | 青岛海之林生物科技开发有限公司 | Plant-based temperature-sensitive gel skin jelly and preparation method thereof |
CN115039872B (en) * | 2022-07-22 | 2024-01-16 | 青岛海之林生物科技开发有限公司 | Plant-based thermosensitive gel jelly and preparation method thereof |
CN115322449A (en) * | 2022-09-16 | 2022-11-11 | 东莞东美食品有限公司 | Preparation process of modified starch plant capsule |
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