CN104258336B - A kind of traditional Chinese powder medicine for application treatment senile hypertension - Google Patents
A kind of traditional Chinese powder medicine for application treatment senile hypertension Download PDFInfo
- Publication number
- CN104258336B CN104258336B CN201410498889.0A CN201410498889A CN104258336B CN 104258336 B CN104258336 B CN 104258336B CN 201410498889 A CN201410498889 A CN 201410498889A CN 104258336 B CN104258336 B CN 104258336B
- Authority
- CN
- China
- Prior art keywords
- parts
- traditional chinese
- medicine
- hypertension
- powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/754—Evodia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A kind of traditional Chinese powder medicine for application treatment senile hypertension, it is made up of the traditional Chinese medicine ingredients of following parts by weight：1.5 3 parts of clerodendron trichotomum, 15 parts of evodia rutaecarpa, 1.5 8 parts of rhizoma zingiberis, 0.5 3 parts of Ligusticum wallichii, 2.5 8 parts of dried orange peel, 2.5 5 parts of fructus alpiniae oxyphyllae, 3 10 parts of hawthorn, 2 10 parts of Radix Angelicae Sinensis, 1.5 5 parts of selfheal, 2.5 8 parts of cassia twig, 28 parts of the seed of feather cockscomb, 1.5 3 parts of radix scutellariae, 25 parts of yncaria stem with hooks.The preparation process of the traditional Chinese powder medicine is：The traditional Chinese medicine ingredients are ground and mixed for powder, pasty state is tuned into vinegar and clear water mixed solvent.The present invention produces stimulation and osmosis by the way that traditional Chinese powder medicine is affixed on into Yongquan acupoint, to meridian point, and then is played a role by " medicine cave economic benefits and social benefits ", so as to effectively treat disease；The dosage for treat aged hypertensives, effectively reducing antihypertensive drugs is used in combination in traditional Chinese powder medicine cooperation antihypertensive drugs, so as to alleviate the adverse reaction of medicine, improves the quality of life of aged patients with hypertension.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, specifically, is to be related to one kind to be directed to aged patients with hypertension, has decompression
Effect sticks traditional Chinese powder medicine.
Background technology
With the aggravation of world population ages, gerontal patient occupies increasing ratio in total patient groups, convex
Geratologous particularity is shown.The treatment of senile hypertension is problem important in cardiovascular field, and current society
Problem.Epidemiology survey shows, as aging population accelerates, senile hypertension illness rate does not reduce not only, has on the contrary
Ascendant trend.In China's elderly population, hyperpietic just has 1 people to suffer from more than more than 80,000,000 in about every 2 the elderlys
Hypertension, the Prevalence of Hypertension for separately having studies have shown that urban elderly population are more than 60% even more high, senile hypertension
Preventing and treating problem be the research of Medical circle one of matter of utmost importance.
Senile hypertension has its own feature, as simple systolic hypertension illness rate is high, diastolic pressure level is relatively low, pulse pressure
Increase, the features such as fluctuation is big, morning peak height blood pressure phenomenon is notable and complication is more.Therefore, senile hypertension treatment is more young
Hypertension is more complicated, also more difficult.How according to the characteristics of old cardiovascular disease, it is pendulum to formulate practicable therapeutic scheme
A key subjects in face of each medical personnel.In recent years, as medical science develops rapidly, senile hypertension basis is ground
Study carefully and deepened continuously with clinical practice, a large amount of evidence-based medicals emerge in an endless stream, and aged patients with hypertension has been obtained good doctor
Control, the controlling of blood pressure rate of patient has declined.
It is well known, however, that the elderly is a special colony.It is clinical because infirmities of age has more diseases
The features such as performance concealment is not true to type, and quickly grows, sudden death rate height, and adverse drug reaction is more, and complication is more, was especially treating
Influenceed significantly by intelligence, psychology, mental element in journey, the more other crowds of compliance that it is treated are worse.Therefore, by high blood pressure
The generality rule of diagnosis and treatment is applied to the elderly, and the careless omission of diagnosis and treatment scheme, treatment certainly will may be brought not to reach
Expected Results, or there is situations such as multi-medicament reaction.
External treatment of tcm be conceived to it is integrally-regulated, improve symptom positive effect, patients ' life quality can be effectively improved；Simultaneously
Operation has advantages such as " letters, just, test, be honest and clean ", substantially increases the compliance of patient.Acupoint application treatment be it is a kind of it is conventional in
Cure external therapy.Under the theoretical guidance of Chinese medicine meridian, relevant medicine is placed in acupuncture point part according to the characteristics of acupuncture point and medicine
Skin, the function of meridional point is combined with the pharmacological action of medicine, curative effect caused by it is both that medicine pharmacology is made
Result, and channels and collaterals and acupuncture points on the human body embody to human body regulatory function, so as to YIN and YANG balance regulating, strengthening vital QI to eliminate pathogenic factors, dredging the channel, reach
The purpose of disease is treated, and adjusts and improve the resistance against diseases of body.Yongquan acupoint is located at before vola 1/3rd recess, foot
The well cave of few cloudy kidney channel, passes through the twelve regular channels and eight extra-channel, has good therapeutic action again.
In summary, if can research and develop a kind of steady, esy to use, safe and reliable with being depressured for senile hypertension
New formulation, will be serious hope and the Gospel of many patients, and urgent clinical needs solve the problems, such as.
The content of the invention
It is an object of the invention to provide a kind of traditional Chinese powder medicine for application treatment senile hypertension, by by powder of Chinese traditional medicine
Yongquan acupoint is affixed on after agent allotment, stimulation and osmosis are produced to meridian point, playing decompression by " medicine cave economic benefits and social benefits " makees
With so as to effectively treat disease.
To realize the above-mentioned purpose of the present invention, the present invention adopts the following technical scheme that.
The present invention is made up of the traditional Chinese medicine ingredients of following parts by weight：Clerodendron trichotomum 1.5-3 parts, evodia rutaecarpa 1-5 parts, rhizoma zingiberis
1.5-8 parts, Ligusticum wallichii 0.5-3 parts, dried orange peel 2.5-8 parts, fructus alpiniae oxyphyllae 2.5-5 parts, hawthorn 3-10 parts, Radix Angelicae Sinensis 2-10 parts, selfheal
1.5-5 parts, cassia twig 2.5-8 parts, seed of feather cockscomb 2-8 parts, radix scutellariae 1.5-3 parts, yncaria stem with hooks 2-5 parts.
The present invention is used for the preparation process of the traditional Chinese powder medicine of application treatment senile hypertension：The traditional Chinese medicine ingredients are ground as powder
End mixes, and is tuned into pasty state with mixed solvents such as vinegar and clear water, the wherein usage ratio of vinegar, water and herb powder is 2:1:1.
The present invention is used for the application method of the traditional Chinese powder medicine of application treatment senile hypertension：1. patch is fully rested before cave；②
Patient takes dorsal position；3. adhesive plaster is cut into 3cm × 3cm blockages, the traditional Chinese powder medicine that sticks for treating hypertension is attached in adhesive plaster
Entreat standby；4. sterilizing spring acupuncture point with 75% cotton ball soaked in alcohol, the adhesive plaster for posting traditional Chinese powder medicine is directed at spring acupuncture points sticking；Each
The course for the treatment of is 4 weeks.
In the prescription of the present invention.
Clerodendron trichotomum, channel tropism：Liver Channel.Flavour of a drug：It is pungent, bitter, the property of medicine：It is cool.Take its efficacy effect：Dispelling wind and eliminating dampness hypotensive.
Evodia rutaecarpa, channel tropism：Liver Channel, the spleen channel, stomach, flavour of a drug：It is pungent, bitter, the property of medicine：Temperature.Take its efficacy effect：Eliminating cold to stop pain.
Rhizoma zingiberis, channel tropism：Stomach, lung channel, the spleen channel, flavour of a drug：It is pungent, the property of medicine：Heat.Take its efficacy effect：Warming spleen and stomach for dispelling cold, Hui Yangtong
Arteries and veins.
Ligusticum wallichii, channel tropism：Gallbladder channel, Liver Channel, flavour of a drug：It is pungent, the property of medicine：Temperature.Take its efficacy effect：Blood-activating and qi-promoting, wind-expelling pain-stopping.
Dried orange peel, channel tropism：Lung channel, the spleen channel, flavour of a drug：It is pungent, bitter, the property of medicine：Temperature.Take its efficacy effect：Regulating qi-flowing for strengthening spleen, eliminating dampness
Phlegm.
Fructus alpiniae oxyphyllae, channel tropism：The spleen channel, kidney channel, flavour of a drug：It is pungent, the property of medicine：Temperature.Take its efficacy effect：Warm spleen, warm up kidney.
Hawthorn, channel tropism：Stomach, the spleen channel, Liver Channel, flavour of a drug：It is sour, sweet, the property of medicine：Temperature.Take its efficacy effect：Digestion gathered food, change stagnant
The stasis of blood.
Radix Angelicae Sinensis, channel tropism：Liver Channel, the heart channel of Hang-Shaoyin, the spleen channel, flavour of a drug：It is sweet, pungent, the property of medicine：Temperature.Take its efficacy effect：Replenishing and activating blood, profit
Intestines defaecation.
Selfheal, channel tropism：Gallbladder channel, Liver Channel, flavour of a drug：It is pungent, bitter, the property of medicine：It is cold.Take its efficacy effect：Clear liver and improve vision；Dissipating bind solution
Poison.
Radix scutellariae, channel tropism：Lung channel, gallbladder channel, stomach, large intestine channel, flavour of a drug：Hardship, the property of medicine：It is cold.Take its efficacy effect：Heat-clearing is dry
It is wet.
Yncaria stem with hooks, channel tropism：Liver Channel, pericardium channel, flavour of a drug：It is sweet, the property of medicine：It is slightly cold.Take its efficacy effect：Removing heat from the liver, Pinggan Yang.
Prescription compatibility lexical or textual analysis of the present invention：Clerodendron trichotomum, evodia rutaecarpa are monarch drug in a prescription, and the traditional Chinese medical science thinks, liver belongs to wood, and hypertension is irritability
Excessively high Sheng, evodia rutaecarpa are soothing the liver good medicine.Clerodendron trichotomum dispelling wind and eliminating dampness hypotensive.Evodia rutaecarpa compatibility rhizoma zingiberis simultaneously：Evodia rutaecarpa middle benefit gas
Lower gas and drop inverse；Rhizoma zingiberis warming spleen and stomach for dispelling cold, Papillary have mutual reinforcement between effect.Evodia rutaecarpa compatibility Radix Angelicae Sinensis：Evodia rutaecarpa obtains Radix Angelicae Sinensis, and then temperature dissipates
Without impairment of yin blood, Radix Angelicae Sinensis obtains evodia rutaecarpa and then enriched blood without stagnating.Selfheal is used to treat headache, dizziness, and pharmacological research has drop blood
Pressure acts on, and modern clinic helps decompression to Hypertension.Radix scutellariae：Removing damp-heat, purging intense heat and detonicating, for Liver Channel real heat
High blood pressure, play the role of to eliminate dizziness, headache, bitter taste, vexed.Yncaria stem with hooks：Soothing the liver is stopped working heat-clearing, available for liver-yang hyperactivity institute
The diseases such as the dizziness of cause, headache, hot eyes.
Beneficial effects of the present invention compared with prior art.
The present invention provides a kind of traditional Chinese powder medicine for application treatment senile hypertension, the 13 taste drug matchings rule of prescription
Rule is based on basic theory of tcm, and it is formulated tcm causa morbi, the interpretation of the cause, onset and process of an illness of the senile hypertension that hits, is gushed by the way that traditional Chinese powder medicine is applied to
Spring cave, stimulation and osmosis are produced to meridian point, and then played a role by " medicine cave economic benefits and social benefits ", so as to reach treatment
The purpose of disease.Being used in combination to treat aged hypertensives for traditional Chinese powder medicine cooperation antihypertensive drugs, effectively reduces decompression
The dosage of medicine, so as to alleviate the adverse reaction of medicine, improve the quality of life of aged patients with hypertension.
Embodiment
Embodiment 1.
The present embodiment provides a kind of traditional Chinese powder medicine for application treatment senile hypertension, is made up of following traditional Chinese medicine ingredients
's：8 grams of clerodendron trichotomum, 12 grams of evodia rutaecarpa, 15 grams of rhizoma zingiberis, 6 grams of Ligusticum wallichii, 25 grams of dried orange peel, 18 grams of fructus alpiniae oxyphyllae, 25 grams of hawthorn, Radix Angelicae Sinensis 12
Gram, 9 grams of selfheal, 15 grams of cassia twig, 12 grams of the seed of feather cockscomb, 6 grams of radix scutellariae, 10 grams of yncaria stem with hooks.That is Chinese medicine material parts by weight are：Clerodendron trichotomum
2 parts, 3 parts of evodia rutaecarpa, 3.75 parts of rhizoma zingiberis, 1.5 parts of Ligusticum wallichii, 6.25 parts of dried orange peel, 4.5 parts of fructus alpiniae oxyphyllae, 6.25 parts of hawthorn, 3 parts of Radix Angelicae Sinensis,
2.25 parts of selfheal, 3.75 parts of cassia twig, 3 parts of the seed of feather cockscomb, 1.5 parts of radix scutellariae, 2.5 parts of yncaria stem with hooks.
The present embodiment is used for the preparation process of the traditional Chinese powder medicine of application treatment senile hypertension：By the traditional Chinese medicine ingredients grind for
Powder mixes, and is tuned into pasty state with mixed solvents such as vinegar and clear water, the wherein usage ratio of vinegar, water and herb powder is 2:1:
1。
1. clinical data.
1.1 general information.
61 cases are Geriatrics Dept. inpatient, are randomly divided into two groups, i.e., control group and stick group.Control group 31
Example, wherein man 16, female 15；It is -83 years old 60 years old age, average 76.3 years old；The course of disease -32 years 5 months, it is average 12.5 years.Stick
Group 30, wherein man 15, female 15；It is -84 years old 61 years old age, average 77.1 years old；The course of disease -30 years 6 months, it is average 13.2 years.
Through statistical analysis, there was no significant difference at age, sex, the course of disease etc. by two groups of patients, has comparativity.
1.2 case selection.
Inclusive criteria reference《Chinese hypertension prevention and control guide》With《Senile hypertension Clinics and Practices China Consensus of experts》：
1. previously there is clear and definite hyperpiesia history；2. age 60-85 year；3. below standard 1 grade and 2 grades of high blood are not treated or treated
Pressure：The non-sitting systolic blood pressure of measure right upper extremity on the same day >=140mmHg but ＜ 180mmHg, and（Or）Right upper extremity SiDBP >=
90mmHg but ＜ 110mmHg；4. voluntary participation and it can cooperate with doctor.
Exclusion standard：1. clear and definite secondary hypertension, accelerated hypertension and other may cause heart discharge increase and
The elevated diseases of SBP such as aortic incompetence, aortic sinus fistula, anemia, hyperthyroidism etc.；2. severe cardiopulmonary
Insufficiency；3. serious hepatic renal dysfunction and disease of hematopoietic system；4. 3 grades of hypertension；5. allergic constitution person, therapeutic process
In person is not resistant to medicine.
2. treatment method.
2.1 stick group：Using levo-amlodipine 2.5mg, once a day, orally；Controlling using the present embodiment simultaneously
That treats hypertension sticks traditional Chinese powder medicine point-application Yongquan acupoint, once a day.
2.2 control group：Using levo-amlodipine 2.5mg, once a day, orally.
2.3 observation item：1. quality of life：The scoring of Du Shi hypertension quality of life scale is determined, is born after training by special messenger
Blame to assign to scale and divide；2. blood pressure level：The point of every morning 9. -9 30 minutes, patient by special messenger measure arteria brachialis after resting 10 minutes
Blood pressure level, sphygmomanometer is by calibration；3. safety indexes：Blood urine is just conventional, hepatic and renal function, is examined by clinical laboratory's uniform machinery
And check.
2.4 statistical method：Using SPSS10.0 statistical softwares, two groups of othernesses, which compare, uses Chi-square Test.
3. curative effect determinate standard and treatment results.
3.1 curative effect determinate standard.
3.1.1. Evaluation on quality of life.
Standard is scored at Du Shi hypertension quality of life scale, the quality of life after evaluation hypertensive patient's treatment improves
Situation.Improvement rate（%）=（Total score after total score-treatment before treatment）Total score × 100% before/treatment.Evaluation criteria：Improvement rate >=
50% is effective；Improvement rate >=25% is effective；Improvement rate ＜ 25% is invalid.
3.1.2. efficacy of antihypertensive treatment is evaluated.
Follow-up 4 weeks, the scoring of Du Shi hypertension quality of life scale, brachial arterial pressure decreasing value are determined at the end of follow-up.It is right
Two groups of therapeutic effect carries out statistical procedures.
With reference to 1993《New Chinese medicine guideline of clinical investigations》In《New Chinese medicine Hypertension clinical research refers to
Lead principle》Standard.It is effective：Diastole drops 10mmHg or more, and reach normal range (NR)；Or diastole drops 20mmHg or
More than；Effectively：Diastole drops are not as good as 10mmHg but reach normal range (NR)；Or decline 10 ~ 19mmHg, but not up to normal model
Enclose；It is invalid：Not up to above standard.
The comparison of 3.2 two groups of brachial arterial pressure changes（It is shown in Table 1）：Stick group it is effective 12, effective 15, invalid 3, always
Effective percentage 90.00%；Effective 10 of control group, effective 14, invalid 7, total effective rate 77.42%.It is statistically analyzed, sticks
Group total effective rate is better than control group (P<0.05).
Table 1：The comparison of two groups of brachial arterial pressure changes.
| Case number | It is effective | Effectively | It is invalid | Total effective rate（%） | |
| Stick group | 30 | 12 | 15 | 3 | 90.00 |
| Control group | 31 | 10 | 14 | 7 | 77.42 |
Note：Control group is with sticking more variant, the P ＜ 0.05 of group.
As can be seen here, for two groups of patients after treatment, the brachial arterial pressure reduction level for sticking group is better than control group（P<
0.05）.
3.3 two groups of qualities of life, which improve, to be compared（It is shown in Table 2）：Effective 11 of group is sticked, it is effective 17, invalid 2, total effective
Rate 93.33%；Effective 9 of control group, effective 16, invalid 6, total effective rate 80.65%.It is statistically analyzed, it is total sticks group
Effective percentage is better than control group（P<0.05）.
Table 2：The scoring of Du Shi hypertension quality of life scale is compared.
| Case number | It is effective | Effectively | It is invalid | Total effective rate（%） | |
| Stick group | 30 | 11 | 17 | 2 | 93.33 |
| Control group | 31 | 9 | 16 | 6 | 80.65 |
Note：Control group is with sticking more variant, the P ＜ 0.05 of group.
As can be seen here, after two groups of patient's treatments, the Du Shi hypertension quality of life scale scoring improvement level for sticking group is excellent
In control group（P<0.05）.
It can be seen from table 1 and combination table 2, the traditional Chinese powder medicine of spring point-application the present embodiment, stick group and be better than control group.
3.4 adverse reaction：Two groups of pretherapy and post-treatment blood urines are just conventional, hepatic and renal function has no that significant clinic is abnormal.
Conclusion：The traditional Chinese powder medicine treatment aged hypertensives of spring point-application the present embodiment have the effect of preferable, not only
It can further reduce blood pressure, the life quality of patient can also be obviously improved.
Embodiment 2.
The present embodiment provides a kind of traditional Chinese powder medicine for application treatment senile hypertension, is by following parts by weight
Medicine composition composition：2.5 parts of clerodendron trichotomum, 4 parts of evodia rutaecarpa, 5 parts of rhizoma zingiberis, 1 part of Ligusticum wallichii, 2.5 parts of dried orange peel, 3 parts of fructus alpiniae oxyphyllae, hawthorn 3
Part, 6 parts of Radix Angelicae Sinensis, 3 parts of selfheal, 6 parts of cassia twig, 5 parts of the seed of feather cockscomb, 2 parts of radix scutellariae, 3 parts of yncaria stem with hooks.
The present embodiment is used for the preparation process of the traditional Chinese powder medicine of application treatment senile hypertension：By the traditional Chinese medicine ingredients grind for
Powder mixes, and is tuned into pasty state with mixed solvents such as vinegar and clear water, the wherein usage ratio of vinegar, water and herb powder is 2:1:
1。
Embodiment 3.
The present embodiment provides a kind of traditional Chinese powder medicine for application treatment senile hypertension, is by following parts by weight
Medicine composition composition：3 parts of clerodendron trichotomum, 5 parts of evodia rutaecarpa, 6 parts of rhizoma zingiberis, 2 parts of Ligusticum wallichii, 5 parts of dried orange peel, 3.5 parts of fructus alpiniae oxyphyllae, 9 parts of hawthorn,
8 parts of Radix Angelicae Sinensis, 3.5 parts of selfheal, 5 parts of cassia twig, 4 parts of the seed of feather cockscomb, 3 parts of radix scutellariae, 4 parts of yncaria stem with hooks.
The present embodiment is used for the preparation process of the traditional Chinese powder medicine of application treatment senile hypertension：By the traditional Chinese medicine ingredients grind for
Powder mixes, and is tuned into pasty state with mixed solvents such as vinegar and clear water, the wherein usage ratio of vinegar, water and herb powder is 2:1:
1。
Claims (5)
- A kind of 1. traditional Chinese powder medicine for application treatment senile hypertension, it is characterised in that：Described traditional Chinese powder medicine is by following The traditional Chinese medicine ingredients composition of parts by weight：It is clerodendron trichotomum 1.5-3 parts, evodia rutaecarpa 1-5 parts, rhizoma zingiberis 1.5-8 parts, Ligusticum wallichii 0.5-3 parts, old Skin 2.5-8 parts, fructus alpiniae oxyphyllae 2.5-5 parts, hawthorn 3-10 parts, Radix Angelicae Sinensis 2-10 parts, selfheal 1.5-5 parts, cassia twig 2.5-8 parts, feather cockscomb Sub- 2-8 parts, radix scutellariae 1.5-3 parts, yncaria stem with hooks 2-5 parts.
- 2. it is used for the traditional Chinese powder medicine of application treatment senile hypertension as claimed in claim 1, it is characterised in that：Described Chinese medicine Powder is made up of the traditional Chinese medicine ingredients of following parts by weight：2 parts of clerodendron trichotomum, 3 parts of evodia rutaecarpa, 3.75 parts of rhizoma zingiberis, Ligusticum wallichii 1.5 Part, 6.25 parts of dried orange peel, 4.5 parts of fructus alpiniae oxyphyllae, 6.25 parts of hawthorn, 3 parts of Radix Angelicae Sinensis, 2.25 parts of selfheal, 3.75 parts of cassia twig, the seed of feather cockscomb 3 Part, 1.5 parts of radix scutellariae, 2.5 parts of yncaria stem with hooks.
- 3. it is used for the traditional Chinese powder medicine of application treatment senile hypertension as claimed in claim 1, it is characterised in that：Described Chinese medicine Powder is made up of the traditional Chinese medicine ingredients of following parts by weight：It is 2.5 parts of clerodendron trichotomum, 4 parts of evodia rutaecarpa, 5 parts of rhizoma zingiberis, 1 part of Ligusticum wallichii, old 2.5 parts of skin, 3 parts of fructus alpiniae oxyphyllae, 3 parts of hawthorn, 6 parts of Radix Angelicae Sinensis, 3 parts of selfheal, 6 parts of cassia twig, 5 parts of the seed of feather cockscomb, 2 parts of radix scutellariae, yncaria stem with hooks 3 Part.
- 4. it is used for the traditional Chinese powder medicine of application treatment senile hypertension as claimed in claim 1, it is characterised in that：Described Chinese medicine Powder is made up of the traditional Chinese medicine ingredients of following parts by weight：3 parts of clerodendron trichotomum, 5 parts of evodia rutaecarpa, 6 parts of rhizoma zingiberis, 2 parts of Ligusticum wallichii, dried orange peel 5 parts, 3.5 parts of fructus alpiniae oxyphyllae, 9 parts of hawthorn, 8 parts of Radix Angelicae Sinensis, 3.5 parts of selfheal, 5 parts of cassia twig, 4 parts of the seed of feather cockscomb, 3 parts of radix scutellariae, yncaria stem with hooks 4 Part.
- 5. it is used for the preparation method of the traditional Chinese powder medicine of application treatment senile hypertension as claimed in claim 1, it is characterised in that： The traditional Chinese medicine ingredients are ground and mixed for powder, pasty state is tuned into vinegar and clear water mixed solvent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410498889.0A CN104258336B (en) | 2014-09-26 | 2014-09-26 | A kind of traditional Chinese powder medicine for application treatment senile hypertension |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410498889.0A CN104258336B (en) | 2014-09-26 | 2014-09-26 | A kind of traditional Chinese powder medicine for application treatment senile hypertension |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104258336A CN104258336A (en) | 2015-01-07 |
| CN104258336B true CN104258336B (en) | 2017-12-12 |
Family
ID=52149993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410498889.0A Expired - Fee Related CN104258336B (en) | 2014-09-26 | 2014-09-26 | A kind of traditional Chinese powder medicine for application treatment senile hypertension |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104258336B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524539A (en) * | 2015-01-31 | 2015-04-22 | 陈文兴 | Traditional Chinese medicinal sole center patch for treating hypertension and preparation method thereof |
-
2014
- 2014-09-26 CN CN201410498889.0A patent/CN104258336B/en not_active Expired - Fee Related
Non-Patent Citations (3)
| Title |
|---|
| "吴茱萸贴敷涌泉穴治疗高血压病31例";余学燕等;《河北中医》;20041031;第26卷(第10期);第757页 * |
| "高血压病外治两法";魏加涛等;《祝您健康》;20041231(第4期);第33页 * |
| "高血压病的中医综合治疗";黄淑芳等;《中国临床医生》;20061231;第34卷(第10期);第15－16 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104258336A (en) | 2015-01-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104013835A (en) | Traditional Chinese medicine for treating high blood pressure | |
| CN102028375A (en) | Medicinal pillow for treating hypertension | |
| CN103860734B (en) | A kind ofly treat the stiff Chinese medicine fuming-lotion of Wrist fracture posterior joint and care method | |
| CN104258336B (en) | A kind of traditional Chinese powder medicine for application treatment senile hypertension | |
| CN101732593B (en) | Compound antihypertensive tea | |
| CN103751679A (en) | Preparation method of traditional Chinese medicine for treating liver/kidney-yin-deficiency-type hyperlipemia | |
| CN103127415B (en) | Traditional Chinese medicine for treating post-stroke limb numbness | |
| CN102961561B (en) | Chinese medicinal composition for treating coronary heart disease | |
| CN106334024A (en) | Traditional Chinese medicine preparation for treating lower extremity thrombophlebitis | |
| CN103989954A (en) | Traditional Chinese medicine preparation for treating iron-deficiency anemia | |
| CN104689288B (en) | A kind of Chinese medicine preparation for treating chronic hypotension | |
| CN107260978A (en) | A kind of Chinese medicine composition and its production and use | |
| CN103463176A (en) | Medicament for treating hypertention | |
| CN102614477A (en) | Preparation method of traditional Chinese medicine lotion for treating drowsiness caused ecthyma | |
| CN102614357A (en) | Preparation method of traditional Chinese medicine lotion for treating lumbago type lumbago | |
| CN1247228C (en) | Method for preparing Qi-benefiting and blood circulation-promoting pill for treating insufficienty of heart-qi coronary heart disease | |
| CN104225435A (en) | Traditional Chinese medicine preparation for treating turbid phlegm obstructing type coronary heart disease | |
| CN106727752A (en) | Treat pharmaceutical composition of synovitis and preparation method thereof | |
| CN105878905A (en) | Traditional Chinese medicine composition for treating hypertension, coronary heart diseases, apoplexy and hypoimmunity | |
| CN107261073A (en) | Treat the taste side of rhizoma alismatis Tonga of hypertension | |
| CN105727048A (en) | Chinese medicine composition for treating allergic rhinitis | |
| CN105012546A (en) | Sanhuang foot bath bag for curing diabetic foot and use method thereof | |
| CN104643071B (en) | Health product capable of relieving fatigue | |
| CN105147861A (en) | Traditional Chinese medicinal composition and oral preparation for treating viral skin diseases and preparation method of oral preparation | |
| CN104840774A (en) | Traditional Chinese medicine for treating liver and kidney yin deficiency and liver yang hyperactivity type hypertension |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20171212 Termination date: 20180926 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |