CN104258248A - 一种治疗偏头痛的中药组合物 - Google Patents

一种治疗偏头痛的中药组合物 Download PDF

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CN104258248A
CN104258248A CN201410574557.6A CN201410574557A CN104258248A CN 104258248 A CN104258248 A CN 104258248A CN 201410574557 A CN201410574557 A CN 201410574557A CN 104258248 A CN104258248 A CN 104258248A
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traditional chinese
medicine composition
chinese medicine
radix
migraine
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张翼翀
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/264Aristolochia (Dutchman's pipe)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9062Alpinia, e.g. red ginger or galangal
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

本发明提供了一种治疗偏头痛的中药组合物,由以下重量的药物制备而成:桃仁30g、红花10g、麦冬20g、生地8g、天麻6g、苍术30g、莱菔子10g、牡蛎8g、柴胡12g、决明子20g、细辛40g、桔梗20g、防风40g、寻骨风10g、海浮石20g、川芎60g、胆南星20g、益智仁12g。本发明对偏头痛具有显著地疗效。

Description

一种治疗偏头痛的中药组合物
技术领域
本发明涉及一种治疗偏头痛的药物,具体涉及一种由中草药制备而成的治疗偏头痛的药物。
背景技术
偏头痛是一种临床常见病,是反复发作的一侧或两侧搏动性头痛,为临床常见的特发性头痛,属中医学头风、厥头痛、头痛等范畴。目前临床上多采用化学药物进行治疗,但
是由于化学药物的毒副作用相对较差,在治疗效果上不能令人满意。                                                                                                                                                  
发明内容
   为了解决以上技术问题,本发明提供了一种治疗偏头痛的中药组合物。
本发明的技术方案如下:
一种治疗偏头痛的中药组合物,由以下重量的药物制备而成:桃仁30 g、红花10g、麦冬20 g、 生地8g、天麻6g、苍术30 g、莱菔子10g、牡蛎8g、柴胡12g、决明子20 g、细辛40 g、桔梗20 g、防风40 g、寻骨风10g、海浮石20 g、川芎60 g、胆南星20 g、益智仁12g。
本发明采用如下制备方法,取以上各味,加入8倍量的水煎煮两次,每次2小时,过滤,浓缩至相对密度为1.05-1.1即可。
临床资料
诊断标准
偏头痛西医诊断标准参照《偏头痛诊断与防治专家共识》制定的头痛分类及诊断标准( 偏头痛诊断与防治专家共识组. 偏头痛诊断与防治专家共识[J]·}中华内科杂志,2006,45(8) ;694-696.) 拟定及《中医新药临床研究指导原则》头痛诊断标准( 郑筱萸. 中医新药临床研究指导原则[S]. 北京:中国医药科技出版社,2002 ;105-109.) 拟定:(1) 偏头痛以精神紧张、躯体疲劳、情绪因素、外界刺激、月经来潮、环境改变等为诱因;(2) 头痛表现为阵发性发作的偏侧搏动性疼痛、昏痛、胀痛等,持续时间为数分钟或数小时不等,一般不超过24h,偶有持续长达1 周者,间歇期如常人,经一段间歇期后再次发病,病程多迁延数年;(3) 偏头痛发作时可伴恶心、呕吐、耳鸣或失眠、心烦等症状;(4) 神经系统等理化检
查无特殊。
选取符合上述标准的患者共100 例,其中男50例,女50 例,平均年龄37岁,平均病
程2.5 年。全部患者治疗前全部检查血常规、脑血流图,部分检查脑电图、脑地形图,重者作头颅CT 和MRI 检查。
治疗方法
使用本发明药物进行治疗,一日一剂,分两次服用。以15 天为一个疗程,连续进行两个疗程。
疗效标准
 痊愈:头痛及伴随症状消失,随访6 个月无复发,脑血流图正常;显效:头痛及伴随症状消失,随访6 个月有复发现象,脑血流图基本上正常;好转:头痛发作程度及伴随症状减轻,脑血流图有改善;无效:治疗2 个疗程后头痛及伴随症状无改善。
结果
100例患者经治疗后全部符合痊愈标准,并且治疗过程中未发现明显的不良反应。
具体实施方式
下面结合实施例对本发明作进一步的说明。
实施例1
取桃仁30 g、红花10g、麦冬20 g、 生地8g、天麻6g、苍术30 g、莱菔子10g、牡蛎8g、柴胡12g、决明子20 g、细辛40 g、桔梗20 g、防风40 g、寻骨风10g、海浮石20 g、川芎60 g、胆南星20 g、益智仁12g,加入8倍量的水煎煮两次,每次2小时,过滤,浓缩至相对密度为1.05-1.1即可。       

Claims (1)

1. 一种治疗偏头痛的中药组合物,其特征在于,由以下重量的药物制备而成:桃仁30 g、红花10g、麦冬20 g、 生地8g、天麻6g、苍术30 g、莱菔子10g、牡蛎8g、柴胡12g、决明子20 g、细辛40 g、桔梗20 g、防风40 g、寻骨风10g、海浮石20 g、川芎60 g、胆南星20 g、益智仁12g。
CN201410574557.6A 2014-10-24 2014-10-24 一种治疗偏头痛的中药组合物 Pending CN104258248A (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784501A (zh) * 2015-05-12 2015-07-22 潘连香 一种治疗偏头痛的药剂

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CN102641418A (zh) * 2012-05-14 2012-08-22 文庆贤 一种治疗偏头痛的药剂
CN103007027A (zh) * 2012-12-06 2013-04-03 南通市华东润滑设备有限公司 治疗偏头痛的药丸
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CN102641418A (zh) * 2012-05-14 2012-08-22 文庆贤 一种治疗偏头痛的药剂
CN103007027A (zh) * 2012-12-06 2013-04-03 南通市华东润滑设备有限公司 治疗偏头痛的药丸
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784501A (zh) * 2015-05-12 2015-07-22 潘连香 一种治疗偏头痛的药剂

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