CN104258234A - 一种治疗外阴瘙痒的洗剂 - Google Patents

一种治疗外阴瘙痒的洗剂 Download PDF

Info

Publication number
CN104258234A
CN104258234A CN201410585543.4A CN201410585543A CN104258234A CN 104258234 A CN104258234 A CN 104258234A CN 201410585543 A CN201410585543 A CN 201410585543A CN 104258234 A CN104258234 A CN 104258234A
Authority
CN
China
Prior art keywords
grams
radix
lotion
pruritus vulvae
material medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410585543.4A
Other languages
English (en)
Inventor
张慧俭
仲利娟
张娜
马慧玲
秦小川
李淑荣
耿新生
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henan University of Traditional Chinese Medicine HUTCM
Original Assignee
Henan University of Traditional Chinese Medicine HUTCM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henan University of Traditional Chinese Medicine HUTCM filed Critical Henan University of Traditional Chinese Medicine HUTCM
Priority to CN201410585543.4A priority Critical patent/CN104258234A/zh
Publication of CN104258234A publication Critical patent/CN104258234A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/758—Zanthoxylum, e.g. pricklyash
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

本发明涉及治疗外阴瘙痒的洗剂，可有效解决治疗外阴瘙痒的用药问题，其解决的技术方案是，该洗剂是由重量计的：当归25-35g、川椒25-35g、椿白皮25-35g、黄连25-35g、黄芩25-35g、黄柏25-35g、大黄25-35g、百部25-35g、萆薢17-23g和连翘12-17g作原料药物制成，将原料药物加8-10倍重量的水，煎煮成水煎液，熏洗，本发明组方科学，原料丰富，使用方便，易生产制备，具有灭菌、消炎、止痒之功效，有效用于外阴瘙痒的治疗，是治疗外阴瘙痒药物上的创新。

Description

一种治疗外阴瘙痒的洗剂
技术领域
本发明涉及医药，特别是一种治疗外阴瘙痒的洗剂。
背景技术
外阴瘙痒是外阴各种不同病变所引起的一种自觉症状，为常见多发病，为许多皮肤病所共有，而非一种特异性的疾病。但也可发生于外阴完全正常者。中医称之为“痒风”，本症一般分为限局性、全身性两大类。男女均可发病，以女性多见，外阴瘙痒多位于阴蒂、小阴唇，也可波及大阴唇、会阴甚至肛周等皮损区。长期搔抓可出现抓痕、血痂或继发毛囊炎。当瘙痒严重时，患者多坐卧不安，以致影响生活和工作。但目前的药物由于种种原因，只能缓解和减轻痛苦，不能从根本解决病患，因此，新药的研制势在必行。
发明内容
针对上述情况，为克服现有技术之缺陷，本发明之目的就是提供一种治疗外阴瘙痒的洗剂，可有效解决治疗外阴瘙痒的用药问题。
本发明解决的技术方案是，该洗剂是由重量计的：当归25-35g、川椒25-35g、椿白皮25-35g、黄连25-35g、黄芩25-35g、黄柏25-35g、大黄25-35g、百部25-35g、萆薢17-23g和连翘12-17g作原料药物制成，将原料药物加8-10倍重量的水，煎煮成水煎液，熏洗。
本发明组方科学，原料丰富，使用方便，易生产制备，具有灭菌、消炎、止痒之功效，有效用于外阴瘙痒的治疗，是治疗外阴瘙痒药物上的创新。
具体实施方式
以下结合实施例对本发明的具体实施方式作详细说明。
本发明在具体实施中，可由以下实施例给出。
实施例1
本发明在具体实施中，该洗剂是由重量计的：当归30g、川椒30g、椿白皮30g、黄连30g、黄芩30g、黄柏30g、大黄30g、百部30g、萆薢20g和连翘15g作原料药物制成，将原料药物加8-10倍重量的水，煎煮成水煎液，熏洗。
实施例2
本发明在具体实施中，该洗剂还可由重量计的：当归26g、川椒34g、椿白皮26g、黄连34g、黄芩26g、黄柏34g、大黄26g、百部34g、萆薢18g和连翘16g作原料药物制成，将原料药物加8-10倍重量的水，煎煮成水煎液，熏洗。
实施例3
本发明在具体实施中，该洗剂也可由重量计的：当归34g、川椒26g、椿白皮34g、黄连26g、黄芩34g、黄柏26g、大黄34g、百部26g、萆薢22g和连翘13g作原料药物制成，将原料药物加8-10倍重量的水，煎煮成水煎液，熏洗。
实施例4
本发明在具体实施中，该洗剂还可由重量计的：当归28-32g、川椒28-32g、椿白皮28-32g、黄连28-32g、黄芩28-32g、黄柏28-32g、大黄28-32g、百部28-32g、萆薢19-21g和连翘14-16g作原料药物制成，将原料药物加8-10倍重量的水，煎煮成水煎液，熏洗。
本发明药物是根据君、臣、佐、使的组方，组分间相互支持，具有灭菌、消炎、止痒之功效，有效用于治疗外阴瘙痒，并经临床试验取得了非常满意的有益技术效果，有关临床资料如下：
一、选择病例的标准
外阴瘙痒临床表现为瘙痒、伴有外阴潮湿，分泌物增多、异味或见神疲乏力，腰膝酸软，畏寒肢冷，因此，凡具有以上症状者，均作为选择病例的标准。
二、治疗方案
患者使用本发明的洗液，按处方量作为一剂，每天一剂，每日熏洗2次，早晚各1次， 15天为一个疗程，三个疗程统计效果。
三、疗效评定标准
1、临床治愈：症状全部消失，功能自动恢复正常。
2、显效：全部症状消除或主要症状恢复，能参加正常工作和劳动，统计学t检验，P值均小于0.01（P﹤0.01），经Ridit分析和X2检验，各体征组间、以及各疗效组治疗前后差异均有显著性意义（P﹤0.01）。
3、有效：主要症状基本消除，症状和体征均有不同程度改善。
4、无效：和治疗前相比较，各方面均无进步。
四、统计学处理
采用本发明洗剂对300例患者使用，其中，女176人，男124人。年龄最小为3岁，最大为75岁，平均年龄为39岁。病程最短为1个月，最长为14年零6个月。其中单纯外阴瘙痒108例，占36%；伴外阴潮湿113例，占37.66%；伴分泌物增多、异味79例，占26.33%。见表1：
表1     使用本发明的300例病人症状情况
症   状 例  数 百分率（%）
外阴瘙痒 108 36.00
外阴潮湿 113 37.66
分泌物增多、异味 79 26.33
临床治愈163例，占54.33%；显效99例，占33.00%；好转36例，占12%；无效2例，占0.67%。总有效率为99.33%，见表2：
表2             本发明总疗效统计
项目 痊愈（临控） 显效 好转 无效 总有效率
例数（人） 163 99 36 2 298
百分率% 54.33 33.00 12.00 0.67 99.33
从表2可以看出，本发明在对已用本发明药物治疗者均取得了意想不到的疗效，对外阴瘙痒伴有外阴潮湿、分泌物增多、异味其治愈率分别为54.33%、33.00%、12.00%。对各症状的有效率为99%以上。以上患者治疗、用药中，均未见毒副反应，表明该药是治疗外阴阴瘙痒有效安全的药物。
六、结论
由上述表明，本发明是治疗外阴瘙痒的有效药物，疗效高，有效率高达99%以上，无毒副反应、使用方便，具有很强的实际临床意义，为外阴瘙痒患者提供了良好的治疗条件，是中医药学上的一大创造，造益于社会。

Claims (5)

1.一种治疗外阴瘙痒的洗剂，其特征在于，由重量计的：当归25-35g、川椒25-35g、椿白皮25-35g、黄连25-35g、黄芩25-35g、黄柏25-35g、大黄25-35g、百部25-35g、萆薢17-23g和连翘12-17g作原料药物制成，将原料药物加8-10倍重量的水，煎煮成水煎液。
2.根据权利要求1所述的治疗外阴瘙痒的洗剂，其特征在于，由重量计的：当归30g、川椒30g、椿白皮30g、黄连30g、黄芩30g、黄柏30g、大黄30g、百部30g、萆薢20g和连翘15g作原料药物制成，将原料药物加8-10倍重量的水，煎煮成水煎液。
3.根据权利要求1所述的治疗外阴瘙痒的洗剂，其特征在于，由重量计的：当归26g、川椒34g、椿白皮26g、黄连34g、黄芩26g、黄柏34g、大黄26g、百部34g、萆薢18g和连翘16g作原料药物制成，将原料药物加8-10倍重量的水，煎煮成水煎液。
4.根据权利要求1所述的治疗外阴瘙痒的洗剂，其特征在于，由重量计的：当归34g、川椒26g、椿白皮34g、黄连26g、黄芩34g、黄柏26g、大黄34g、百部26g、萆薢22g和连翘13g作原料药物制成，将原料药物加8-10倍重量的水，煎煮成水煎液。
5.根据权利要求1所述的治疗外阴瘙痒的洗剂，其特征在于，由重量计的：当归28-32g、川椒28-32g、椿白皮28-32g、黄连28-32g、黄芩28-32g、黄柏28-32g、大黄28-32g、百部28-32g、萆薢19-21g和连翘14-16g作原料药物制成，将原料药物加8-10倍重量的水，煎煮成水煎液。
CN201410585543.4A 2014-10-28 2014-10-28 一种治疗外阴瘙痒的洗剂 Pending CN104258234A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410585543.4A CN104258234A (zh) 2014-10-28 2014-10-28 一种治疗外阴瘙痒的洗剂

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410585543.4A CN104258234A (zh) 2014-10-28 2014-10-28 一种治疗外阴瘙痒的洗剂

Publications (1)

Publication Number Publication Date
CN104258234A true CN104258234A (zh) 2015-01-07

Family

ID=52149891

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410585543.4A Pending CN104258234A (zh) 2014-10-28 2014-10-28 一种治疗外阴瘙痒的洗剂

Country Status (1)

Country Link
CN (1) CN104258234A (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108686093A (zh) * 2018-08-10 2018-10-23 徐金莲 一种妇科清洗液

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020062474A (ko) * 2001-01-20 2002-07-26 주식회사 네추라 바이오 캠 여성의 질염 및 냉대하증 치료효능을 갖는 한약재 조성물및 이를 이용하여 제조된 생리대 패드
CN101336991A (zh) * 2008-07-28 2009-01-07 内蒙古医学院 治疗妇科外阴瘙痒及阴道炎的药物
KR20120063076A (ko) * 2010-12-07 2012-06-15 (주)선바이오텍 질염의 예방 또는 치료에 효과가 있는 항균제 조성물과 이를 포함하는 여성용 청결제 조성물

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020062474A (ko) * 2001-01-20 2002-07-26 주식회사 네추라 바이오 캠 여성의 질염 및 냉대하증 치료효능을 갖는 한약재 조성물및 이를 이용하여 제조된 생리대 패드
CN101336991A (zh) * 2008-07-28 2009-01-07 内蒙古医学院 治疗妇科外阴瘙痒及阴道炎的药物
KR20120063076A (ko) * 2010-12-07 2012-06-15 (주)선바이오텍 질염의 예방 또는 치료에 효과가 있는 항균제 조성물과 이를 포함하는 여성용 청결제 조성물

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
符彦成: "三黄五倍子汤熏洗治疗阴部肛门瘙痒症156例", 《陕西中医》 *
马小红: "中西医结合治疗外阴瘙痒60例疗效观察", 《甘肃中医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108686093A (zh) * 2018-08-10 2018-10-23 徐金莲 一种妇科清洗液

Similar Documents

Publication Publication Date Title
CN103099944A (zh) 治疗顽固性失眠的药剂
CN103784890A (zh) 一种治疗骨病的中药组合物
CN103830527A (zh) 一种治疗前列腺炎的制剂
CN104258234A (zh) 一种治疗外阴瘙痒的洗剂
CN103893502A (zh) 一种用于治疗泡性结膜炎的中药
CN103860707A (zh) 治疗外阴瘙痒的外用纯中药制剂
CN104436121B (zh) 一种治疗月经不调、小腹胀满、久不受孕的药物
CN104547683B (zh) 一种治疗慢性胃炎的中药组合物及其制备方法
CN103611027B (zh) 一种临床预防、护理和治疗滴虫性阴道炎的药物组合物
CN103550668B (zh) 一种治疗妇科滑胎病的中药药物
CN103432333B (zh) 一种治疗甲状腺机能减退症的中药有效部位组合物
CN103463292A (zh) 一种治疗银屑病的药物
CN103006826B (zh) 一种治疗女性更年期失眠症的中药复方
CN103638263B (zh) 一种治疗银屑病的中药组合物及其制备方法
CN101983676A (zh) 一种妇科血瘀气滞疗剂
CN101979073A (zh) 一种疏肝理气药剂
CN103520468B (zh) 一种治疗病毒性心肌炎的中药
CN104306511A (zh) 一种治疗血瘀型痔疮的中药组合物
CN104840645A (zh) 一种治疗眩晕的中药
CN104523961B (zh) 一种治疗小儿功能性便秘的药剂
CN103830684A (zh) 一种治疗月经过多的药物组合物及其应用
CN105287758A (zh) 一种治疗荨麻疹的中药
CN104027427B (zh) 一种治疗阴虚血热证型月经先期的中药
CN102028811B (zh) 一种治疗消渴病的中药组合物
CN103768312A (zh) 一种治疗内耳眩晕病的中药有效部位组合物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20150107

WD01 Invention patent application deemed withdrawn after publication