CN104258204B - A kind of Chinese medicine composition and its application in treatment nephrotic syndrome medicine is prepared - Google Patents
A kind of Chinese medicine composition and its application in treatment nephrotic syndrome medicine is prepared Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition, including 5 10 parts of yellow angledtwig magnoliavine root stem and leaf, 6 15 parts of pilose gerbera herb, 3 15 parts of corydalis tuber, 15 25 parts of schefflera arboricola, 9 15 parts of Fructus Hordei Germinatus, 10 15 parts of reticulate millettia, 60 120 parts of 50 100 parts of 25 50 parts of obcordateleaf raspberry fruit or fresh obcordateleaf raspberry fruit, 30 60 parts of Semen Coicis root or fresh Semen Coicis root, 3 10 parts of radix glycyrrhizae.Said composition can be used for the medicine for preparing treatment nephrotic syndrome, can obviously improve the various symptoms of Patients With Nephrotic Symdrome, improves therapeutic effect, cure rate can be effectively improved the health status of Patients With Nephrotic Symdrome more than 92.6%, improve its quality of life.
Description
Technical field
The invention belongs to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition and its prepare treat nephrotic syndrome medicine
In application.
Background technology
Nephrotic syndrome (nephrotic syndrome, NS) refers to as caused by Different types of etiopathogenises, logical with glomerular basement membrane
One group of syndrome based on the Glomerular lesions such as permeability increase companion's glomerular filtration rate(GFR reduction.Clinical manifestation is High-grade Proteinuria
(＞ 3.5g/d), Hypoproteinemia (＜ 30g/L), treating serious edema caused, hyperlipidemia one group of clinical syndrome, i.e., so-called " three
High one is low ".
Current nephrotic syndrome mainly takes following several drugses or method to be treated：
1st, glucocorticoid glucocorticoid is used for kidney trouble, mainly its antiinflammatory action.It can mitigate acute inflammation
When ooze out, stable lysosome membrane reduces fibrinous calmness, reduces capillary permeability and reduces Urine proteins and spill；
In addition, still suppressing the proliferation response in chronic inflammation, fibroblasts are reduced, mitigate the fiber caused by tissue repair
Change.But prolonged application hormone is also easy to produce many side effects, it can such as aggravate the osteopathy of nephrotic syndrome, or even produce aseptic femur
Neck ischemic necrosis；Protein high decomposing state can aggravate azotemia caused by hormone, promote blood uric acid to increase, and induce gout
With aggravation renal hypofunction；Heavy dose application can aggravate hypertension, inspire heart failure sometimes；The infection symptoms of patient when hormone is applied
It is likely to unobvious, is particularly easy to delay diagnosis, causes infection to be spread.
2nd, cytotoxic drug is for hormone therapy is invalid or patient of hormone-dependent type or recurrent, Chang Cai
Cell toxicity medicament co-treatment is used, but such medicine can reduce resistance of human body, and there is the danger of induced tumor.
3rd, Cellular immunity suppression agent and glucocorticosteroidsin in combination application or exclusive use, can reduce albuminuria and improve low
Proteinemia, curative effect is reliable, does not influence to grow, does not suppress hematopoietic cell function.But such medicine also has a variety of side effects, most
Serious side effect is kidney, hepatotoxicity wind agitation.
4th, compared with frequently with but in existing method, Chinese medicine functions only as matching somebody with somebody during the method for the combination of Chinese tradiational and Western medicine is clinical at present
The effect of Western medicine is closed, for reducing side effect, or curative effect is improved, fails to give full play to " the musting it " of traditional Chinese medicine, sample simultaneous
The advantage controlled, conditions of patients easily recurs.
5th, although pure Chinese medicine treatment traditional Chinese medicine treatment nephrotic syndrome has certain curative effect, but the slow, treatment that often works
Cycle length, therapeutic process are complicated, cause the compliance of patient poor.It is selected from famous doctor of Chinese Medicine Ma Lianxiang treatment nephrotic syndromes
Prescription Yishen Jianpi soup, its prescription is：12 grams of the Radix Astragali, 9 grams of Radix Codonopsis, 9 grams of rhizoma atractylodis macrocephalae, 9 grams of stir-baked RHIZOMA DIOSCOREAE, 4 grams of radix glycyrrhizae, Poria cocos 9
Gram, 9 grams of stone reed, 9 grams of fructus crataegi cuneatae, 9 grams of the red sage root, 9 grams of dogwood meat processed.Usage daily 1 dose, takes 2 times day to be decocted in water for oral dose.Required treatment
Process is longer, and curative effect is not satisfactory, still has greater room for improvement.
Therefore, although the medicine and method that can be used to treat nephrotic syndrome at present are a lot, but in efficient, treatment week
In terms of phase, recurrence rate, side effect, there are different short slabs, so the thinking of adjustment Chinese traditional treatment nephrotic syndrome, exploitation
New Chinese prescription is well worth doing.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating nephrotic syndrome, to solve prior art to nephrosis
The treated effect of syndrome is low, side effect is big, the problem of easily recur.
In order to realize the purpose of the present invention, following technical scheme is inventor provided.
A kind of Chinese medicine composition, is made up of the prepared slices of Chinese crude drugs of following parts by weight：5-10 parts of yellow angledtwig magnoliavine root stem and leaf, pilose gerbera herb 6-15
Part, 3-15 parts of corydalis tuber, 15-25 parts of schefflera arboricola, 9-15 parts of Fructus Hordei Germinatus, 10-15 parts of reticulate millettia, 25-50 parts of obcordateleaf raspberry fruit or cadmium yellow
Steep 60-120 parts of 50-100 parts of fruit, 30-60 parts of Semen Coicis root or fresh Semen Coicis root, 3-10 parts of radix glycyrrhizae.
Above-mentioned Chinese medicine composition, is made up of the prepared slices of Chinese crude drugs of following parts by weight：6-9 parts of yellow angledtwig magnoliavine root stem and leaf, 8-12 parts of pilose gerbera herb,
5-13 parts of corydalis tuber, 18-22 parts of schefflera arboricola, 10-14 parts of Fructus Hordei Germinatus, 11-14 parts of reticulate millettia, 30-45 parts of obcordateleaf raspberry fruit or cadmium yellow bubble
70-110 parts of 60-90 parts of fruit, 35-55 parts of Semen Coicis root or fresh Semen Coicis root, 4-9 parts of radix glycyrrhizae.
Above-mentioned Chinese medicine composition, is made up of the prepared slices of Chinese crude drugs of following parts by weight：7-8 parts of yellow angledtwig magnoliavine root stem and leaf, 9-11 parts of pilose gerbera herb,
7-11 parts of corydalis tuber, 19-21 parts of schefflera arboricola, 11-13 parts of Fructus Hordei Germinatus, 12-13 parts of reticulate millettia, 35-40 parts of obcordateleaf raspberry fruit or cadmium yellow bubble
80-100 parts of 70-80 parts of fruit, 40-50 parts of Semen Coicis root or fresh Semen Coicis root, 5-8 parts of radix glycyrrhizae.
Above-mentioned Chinese medicine composition, is made up of the prepared slices of Chinese crude drugs of following parts by weight：8 parts of yellow angledtwig magnoliavine root stem and leaf, 10 parts of pilose gerbera herb prolongs recklessly
76 parts of 9 parts of rope, 20 parts of schefflera arboricola, 12 parts of Fructus Hordei Germinatus, 12 parts of reticulate millettia, 38 parts of obcordateleaf raspberry fruit or fresh obcordateleaf raspberry fruit, 45 parts of Semen Coicis root or
Fresh 90 parts of Semen Coicis root, 6 parts of radix glycyrrhizae.
Above-mentioned Chinese medicine composition can be used for the medicine for preparing treatment nephrotic syndrome.
Above-mentioned Chinese medicine composition, can add pharmaceutically acceptable auxiliary material, conventionally be prepared into a variety of oral formulations,
Including decoction, granule, capsule, the water-bindered pill, honeyed bolus.It is most fast with decoction action in various preparations, it is preferred formulation.Have in medicine
In the case that effect composition is suitable, different agents can reach identical curative effect.
According to the concrete condition of Patients With Nephrotic Symdrome, the concrete composition of Chinese medicine composition of the present invention can be carried out suitably
Adjustment.In use, the consumption of fresh obcordateleaf raspberry fruit and fresh Semen Coicis root is the two of its corresponding dry medicine materical crude slice obcordateleaf raspberry fruit and Semen Coicis root respectively
Times.
The traditional Chinese medical science is belonged to " oedema ", " consumptive disease " category according to the symptom of nephrotic syndrome.This sick protracted course of disease, with the passing of time
Healthy tendency is lost, the deficiency of vital energy and hematogenous blockage, the retardance of prolonged illness mechanism of qi can cause blood stasis, with the wet mutual knot of water and aggravate the state of an illness.With lung, spleen,
The dirty healthy tendency virtual loss of kidney three is this, and blood stasis is mark, the deficiency of vital energy and blood stasis reciprocal causation, simulataneous insufficiency and excessive.Therefore, treated both principal and secondary aspect of disease according to the traditional Chinese medical science
Principle, inventor thinks that the rules for the treatment of of nephrotic syndrome should be：Vital energy regualting and blood circulation-promoting, warm spleen kidney tonifying, freeing lung-Qi and eliminating damp.Based on this principle,
The invention provides the Chinese medicine composition of above-mentioned treatment nephrotic syndrome.
In Chinese medicine composition provided by the present invention, yellow angledtwig magnoliavine root stem and leaf：Promoting the circulation of qi, promoting blood circulation dissipates the stasis of blood, analgesic；Pilose gerbera herb：Promoting the circulation of qi is lived
Blood, clearing heat and detoxicating, facilitaing lung cough-relieving；Corydalis tuber：Promoting blood circulation, qi-regulating, cool blood dissipates the stasis of blood；Schefflera arboricola：Promoting qi circulation and relieving pain, activating blood circulation and reducing swelling；Raw wheat
Bud：Promoting the circulation of qi helps digestion, spleen benefiting and stimulating the appetite；Reticulate millettia：Enrich blood, invigorate blood circulation, dredging collateral；Obcordateleaf raspberry fruit：The puckery essence of kidney tonifying；Semen Coicis root：Eliminating dampness and heat, profit
Urine, strengthening the spleen and stomach, consumer edema；Radix glycyrrhizae：Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, coordinating the drug actions of a prescription.
Chinese medicine composition provided by the present invention with promoting the circulation of qi, promoting blood circulation, dissipate stasis of blood class medicine yellow angledtwig magnoliavine root stem and leaf, pilose gerbera herb, corydalis tuber,
Schefflera arboricola nurses one's health spleen and the loss of kidney healthy tendency, is main ingredient.With Fructus Hordei Germinatus promoting the circulation of qi helps digestion, spleen benefiting and stimulating the appetite helps the foundation of acquired constitution, the life of solid and gas blood
The source of change；Enriched blood, invigorated blood circulation with reticulate millettia, dredging collateral makes up spleen kidney；With the puckery essence of obcordateleaf raspberry fruit kidney tonifying, three medicines play altogether blood-nourishing enrich blood, kidney-nourishing
The work(of controlling nocturnal emission with astringent drugs, is adjuvant.Using eliminating dampness and heat, diuresis, strengthening the spleen and stomach Semen Coicis root as adjutant；Radix glycyrrhizae is invigorated the spleen and benefited qi, clearing heat and detoxicating,
Coordinating the drug actions of a prescription, to make medicine.Each component, which cooperates, to be cooperateed with, and nephrotic syndrome is treated both principal and secondary aspect of disease, and without any side effects, is controlled
Treat efficient up to more than 92.6%.
Embodiment
Content of the present invention is further described in detail with reference to specific embodiment.
The clinical test of embodiment 1
(1) case selection
Between in May, -2013 in May, 2010,60 Patients With Nephrotic Symdromes are screened, have different degrees of oedema, a large amount of
The clinical manifestations such as albuminuria, Hypoproteinemia, laboratory examination results point out Urine proteins more than 3.5g/24h, and plasma albumin is low
In 30g/L, meet 2003《Diagnosis of nephropathy and treatment and criterion of therapeutical effect seminar summary》In diagnostic criteria, and exclude and be
Secondary cases nephrotic syndrome caused by system property lupus erythematosus, diabetes, hypertension, HSPN etc..
(2) case-data
Include 60 patients of observation, its age between 22-61 Sui, the course of disease 7-96 months, by table of random number mono blind method
It is grouped, test group 30, control group 30.Test group male 18, women 12, average age is 46.18 scholars 9.79
Year, average course of disease 46.52 ± 8.41 months；Control group male 19, women 11, average age is 45.61 scholar 9.84 years old, average
The course of disease 45.04 ± 9.4 months.Between two groups the age, sex, smoking, drink, indifference in terms of body weight, schooling, with can
Compare property.
(3) treatment method
Test group：Chinese medicine composition of the present invention is put into marmite, plus appropriate water, did not had Chinese medicine, and was decocted after water boiling
30 minutes, concoction is filtered out, obtain 100-150ml, then the dregs of a decoction in marmite added water after continuing to decoct 30 minutes, filter out medicine
Juice 100-150ml, finally mixes the concoction decocted twice, warmly takes in two times, once in the morning and once at night.
Chinese medicine composition composition is used in test group：Yellow angledtwig magnoliavine root stem and leaf 5-10g, pilose gerbera herb 6-15g, corydalis tuber 3-15g, seven leaves
Lotus 15-25g, Fructus Hordei Germinatus 9-15g, reticulate millettia 10-15g, obcordateleaf raspberry fruit 25-50g or fresh obcordateleaf raspberry fruit 50-100g, Semen Coicis root 30-60g
Or fresh Semen Coicis root 60-120g, radix glycyrrhizae 3-10g.Using when be adjusted according to the specific state of an illness of patient.
Control group：Using conventional prescriptions Yishen Jianpi soup, the same test group of decoction usage.
Control group Yishen Jianpi soup is constituted：Radix Astragali 12g, Radix Codonopsis 9g, rhizoma atractylodis macrocephalae 9g, stir-baked RHIZOMA DIOSCOREAE 9g, radix glycyrrhizae 4g, Poria cocos
9g, stone reed 9g, fructus crataegi cuneatae 9g, red sage root 9g, dogwood meat processed 9g.
Two groups of patient medication time consistencies, while enjoining patient to take a good rest, keep mood optimistic, keep good life to practise
It is used, rational diet.
(4) efficacy determination
Criterion of therapeutical effect foundation《Primary glomerulopathy parting and treatment diagnostic criteria symposium summary》On kidney
The standard of sick syndrome effect：(1) complete incidence graph：Symptom disappears, and repeatedly surveys Urine proteins feminine gender, and Urine proteins are determined for three days on end
Measure ＜ 0.3g/24h, plasma protein ＞ 39g/L, blood fat, normal renal function；(2) part is alleviated：More than for three days on end, Urine proteins are fixed
Measure as 0.3~2.0g/24h, symptom disappearance, renal function improvement；(3) it is invalid：Urine proteins are without reduction, and renal function is without improvement or dislikes
Change.
(5) statistical method
All data are entered into SPSS17.0 (statistical package for social sciences) software and carry out statistical procedures, metering
Data is with mean ± standard deviationRepresent, examined and compared between being organized using t.
(6) result of the test
Clinical efficacy is observed after treating 8 weeks, compares 24h quantity of proteinuria before and after two groups of treatments, triglycerides, total courage and consolidates
The change of the indexs such as alcohol, prothrombin time, active partial thromboplastin time, fibrinogen, platelet count.
Urine proteins, blood lipids index compare：Compared with pre-treatment, patient 24h albuminuria, T-CHOL, triglycerides etc. refer to
Mark has declined；Compare between two groups, test group index fall is significantly greater, group difference is significantly, statistically significant
(P ＜ 0.05), is shown in Table 1.
Urine proteins, blood lipids index compare before and after 1 two groups of treatments of table
Note：Compared with before treatment, #p ＜ 0.05；Compared with after control group treatment, * p ＜ 0.05
Blood coagulation parameters compare：Compared with before treatment, two groups of patient's prothrombin times, active partial thromboplastin time,
The Blood coagulation parameters such as fibrinogen, platelet count make moderate progress；Compare between two groups, test group target improvement is obvious, between group
Significant difference, statistically significant (P ＜ 0.05), is shown in Table 2.
Blood coagulation parameters compare before and after 2 two groups of treatments of table
Note：Compared with before treatment, #p ＜ 0.05；Compared with after control group treatment, * p ＜ 0.05
Comprehensive therapeutic effect compares：Compared with pre-treatment, control group and test group clinical indices have improvement；Compare between two groups,
Test group curative effect improvement amplitude is significantly greater, and significantly, statistically significant (P ＜ 0.05) is shown in Table 3 to group difference.
Comprehensive therapeutic effect compares before and after 3 two groups of treatments of table
The clinical test of embodiment 2
(1) case selection
2 months in January, -2014 in 2010,108 Patients With Nephrotic Symdromes of screening are as the object of observation, and screening criteria is with real
Apply example 1.
(2) case-data
Include 108 patients of observation, its age between 3-58 Sui, patient's course of disease 6-72 months, by random digit list
Blind is grouped, wherein test group 54, control group 54.Test group male 28, women 26, average age is
29.01 scholars 7.23 years old, average course of disease 38.52 ± 13.41 months；Control group male 25, women 29, average age is 31.09
Scholar 6.49 years old, average course of disease 39.14 ± 13.63 months.Between two groups the age, sex, smoking, drink, the side such as body weight, schooling
Face indifference, with comparativity.
(3) treatment method
Test group be the same as Example 1.
Control group：Metacortandracin 1mg/ (kgd) is given, a clothes, reaches research on maximum utilized quantity, after 8 weeks gradually from daily morning at 8 weeks
Decrement, successively decreases weekly the 10% of former dosage.
Enjoin patient to take a good rest during medication, keep mood optimistic, keep good habits and customs, rational diet.
(4) efficacy determination
Be the same as Example 1.
(5) statistical method
Be the same as Example 1.
(6) result of the test
Clinical efficacy is observed after treating 8 weeks, compares 24h quantity of proteinuria before and after two groups of treatments, triglycerides, total courage and consolidates
The change of the indexs such as alcohol, prothrombin time, active partial thromboplastin time, fibrinogen, platelet count.
Urine proteins, blood lipids index compare：Compared with pre-treatment, two groups of patient 24h albuminuria, T-CHOLs, triglycerides
Decline etc. index；Compare between two groups, test group fall is significantly greater, group difference is significantly, statistically significant
(P ＜ 0.05), is shown in Table 4.
Urine proteins, blood lipids index compare before and after 4 two groups of treatments of table
Note：Compared with before treatment, #p ＜ 0.05；Compared with after control group treatment, * p ＜ 0.05
Blood coagulation parameters compare：Compared with pre-treatment, two groups of patient's prothrombin times, active partial thromboplastin time,
The Blood coagulation parameters such as fibrinogen, platelet count make moderate progress；Compare between two groups, test group improvement amplitude is significantly greater,
Significantly, statistically significant (P ＜ 0.05) is shown in Table 5 to group difference.
Blood coagulation parameters compare before and after 5 two groups of treatments of table
Note：Compared with before treatment, #p ＜ 0.05；Compared with after control group treatment, * p ＜ 0.05
Comprehensive therapeutic effect compares：Compared with pre-treatment, control group and test group clinical indices have improvement；Compare between two groups,
Test group improvement amplitude is significantly greater, and significantly, statistically significant (P ＜ 0.05) is shown in Table 6 to group difference.
Comprehensive therapeutic effect compares before and after 6 two groups of treatments of table
Embodiment 3 specifically tests case
1st, name：Qin's ×× sex：The male age：24 years old
There is eyelid and double lower limb oedema in September, 2010 without obvious cause and inducement in patient, increases with foam in oliguria, urine
Many, soreness and weakness of waist and knees, oedema is gradually aggravated, and involves whole body.Hospital assay is shown：Total protein 40.6g/L, albumin 23.4g/L, always
Cholesterol 10.9mmol/L, quantity of proteinuria 7.66g/24h, Urine proteins 3+, occult blood-.Kidney is worn biopsy and shown：" minute lesion type
Nephrosis ".When giving oral prednisone 60mg/d, turned out cloudy after 2 weeks, monthly decrement 5mg, during decrement, recurrence is multiple, whenever sharp
Urine proteins occur again when element reduces to 5mg/d, with double lower limb oedema.
Urine proteins 2+, albumin 30g/L, T-CHOL 6.20mmol/L, quantity of proteinuria are chemically examined in October, 2011
1.36g/24h, Dual-eyelid and double lower limb oedema, institute is taken in primary nephrotic syndrome minute lesion type.With of the present invention
Chinese medicine composition is treated, and Urine proteins are checked after 36 days and are turned out cloudy, quantity of proteinuria 0.13g/24h, and edema, which disappears, leaves hospital.Repeatedly
Check and after treatment, Urine proteins are persistently turned out cloudy.
Chinese medicine composition used is specifically comprised：Yellow angledtwig magnoliavine root stem and leaf 8g, pilose gerbera herb 8g, corydalis tuber 10g, schefflera arboricola 22g are raw
Malt 14g, reticulate millettia 10g, obcordateleaf raspberry fruit 40g, Semen Coicis root 50g, radix glycyrrhizae 9g.
2nd, patient's name：Slowly × sex：The male age：56
Patient at the beginning of 2011 because of fatigue after there is face and edema of pair of lower extremities, no frequent micturition, urgent urination, odynuria, gross hematuria
Etc. symptom, the medical routine that has urine examined：Urine proteins 2+, ERY 2+, blood pressure are normal, and attention is not given.Edema is aggravated with regard to indagation afterwards：Urinate egg
White 3+, ERY 2+, are diagnosed as " nephrotic syndrome ", give inducing diuresis to remove edema, Glucocorticoid impact and enough oral medications, in hospital January
Left and right, urine examination is unchanged.Occur whole skin after discharge to fester, it is proposed that oral hormone 40mg, patient's refusal.In March, 2012 looks into：
Urine proteins 3+, ERY 3+, twenty-four-hour urine protein quantification are 4.86g, albumin 11.93g/L.Give Chinese medicine group of the present invention
Compound is treated, and is checked after 8 weeks, and Urine proteins-, ERY-, twenty-four-hour urine protein quantification is 0.27g, and sb.'s illness took a favorable turn goes out
Institute.
The composition of Chinese medicine composition used is yellow angledtwig magnoliavine root stem and leaf 9g, pilose gerbera herb 12g, corydalis tuber 13g, schefflera arboricola 22g, Fructus Hordei Germinatus
14g, reticulate millettia 14g, obcordateleaf raspberry fruit 45g, Semen Coicis root 55g, radix glycyrrhizae 9g.
3rd, patient's name：Liu × sex：Female's age：25
There is anasarca, oliguria, odynuria, high blood pressure after being caught a cold in 2008 in patient, is diagnosed as " nephrotic syndrome ",
Oral prednisone 50mg, once a day, Urine proteins are not turned out cloudy within 4 months.Renal fibroblast of then transferring from one hospital to another is shown：Focal interim glomerulus
Hardening.Prednisone 50mg is taken, once a day, starts decrement after 4 months, monthly subtracts 5mg, while taking Tripterygium wilfordii Polyglycosidium Tablets
20mg, three times a day, Urine proteins are turned out cloudy when prednisone 6 months is taken, when taking Glucosidorum Tripterygll Totorum 7 months, because of tired Urine proteins
Recurrence, continues to give Glucosidorum Tripterygll Totorum increasing to 40mg, three times a day, Urine proteins are not turned out cloudy.In July, 2010 looks into the μ of creatinine 900
Mol/L, anaemia is serious.In October, 2010 uses traditional Chinese medicine composition for treating of the present invention, is aided with peritoneal dialysis treatment, after 6 weeks,
In addition to 155 μm of ol/L of serum creatinine, remaining index is normal, and take a turn for the better discharge.
The composition of Chinese medicine composition used is：Yellow angledtwig magnoliavine root stem and leaf 8g, pilose gerbera herb 10g, corydalis tuber 12g, schefflera arboricola 22g, raw wheat
Bud 14g, reticulate millettia 11g, obcordateleaf raspberry fruit 45g, Semen Coicis root 55g, radix glycyrrhizae 8g.
In summary, Chinese medicine composition of the present invention is used to treat nephrotic syndrome effect significantly, and without any pair
Effect, can effectively improve and cure the various symptoms of Patients With Nephrotic Symdrome, improve the quality of life of patient.
Claims (7)
1. a kind of Chinese medicine composition, it is characterised in that be made up of the prepared slices of Chinese crude drugs of following parts by weight：5-10 parts of yellow angledtwig magnoliavine root stem and leaf, Mao great
6-15 parts of fourth grass, 3-15 parts of corydalis tuber, 15-25 parts of schefflera arboricola, 9-15 parts of Fructus Hordei Germinatus, 10-15 parts of reticulate millettia, obcordateleaf raspberry fruit 25-50
Part or fresh obcordateleaf raspberry fruit 50-100 parts, 60-120 parts of 30-60 parts of Semen Coicis root or fresh Semen Coicis root, 3-10 parts of radix glycyrrhizae.
2. a kind of Chinese medicine composition according to claim 1, it is characterised in that by the prepared slices of Chinese crude drugs system of following parts by weight
Into：6-9 parts of yellow angledtwig magnoliavine root stem and leaf, 8-12 parts of pilose gerbera herb, 5-13 parts of corydalis tuber, 18-22 parts of schefflera arboricola, 10-14 parts of Fructus Hordei Germinatus, reticulate millettia
11-14 parts, 30-45 parts of obcordateleaf raspberry fruit or fresh obcordateleaf raspberry fruit 60-90 parts, 70-110 parts of 35-55 parts of Semen Coicis root or fresh Semen Coicis root, radix glycyrrhizae 4-
9 parts.
3. a kind of Chinese medicine composition according to claim 1, it is characterised in that by the prepared slices of Chinese crude drugs system of following parts by weight
Into：7-8 parts of yellow angledtwig magnoliavine root stem and leaf, 9-11 parts of pilose gerbera herb, 7-11 parts of corydalis tuber, 19-21 parts of schefflera arboricola, 11-13 parts of Fructus Hordei Germinatus, reticulate millettia
12-13 parts, 35-40 parts of obcordateleaf raspberry fruit or fresh obcordateleaf raspberry fruit 70-80 parts, 80-100 parts of 40-50 parts of Semen Coicis root or fresh Semen Coicis root, radix glycyrrhizae 5-
8 parts.
4. a kind of Chinese medicine composition according to claim 1, it is characterised in that by the prepared slices of Chinese crude drugs system of following parts by weight
Into：8 parts of yellow angledtwig magnoliavine root stem and leaf, 10 parts of pilose gerbera herb, 9 parts of corydalis tuber, 20 parts of schefflera arboricola, 12 parts of Fructus Hordei Germinatus, 12 parts of reticulate millettia, obcordateleaf raspberry fruit 38
Part or 90 parts of 76 parts of fresh obcordateleaf raspberry fruit, 45 parts of Semen Coicis root or fresh Semen Coicis root, 6 parts of radix glycyrrhizae.
5. the oral formulations of Chinese medicine composition as described in claim 1-4 any one, it is characterised in that can also be connect including pharmacy
The auxiliary material received.
6. oral formulations of Chinese medicine composition according to claim 5, it is characterised in that the oral formulations include decoction,
Granule, capsule, the water-bindered pill, honeyed bolus.
7. application of the Chinese medicine composition in the medicine for preparing treatment nephrotic syndrome as described in claim 1-4 any one.
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| CN101259232A (en) * | 2008-04-25 | 2008-09-10 | 北京中泰天和科技有限公司 | Chinese medicinal composition for treating nephrotic syndrome and preparation thereof |
| CN102824413A (en) * | 2012-07-14 | 2012-12-19 | 童小桃 | Decoction medicament for treating poor vein type proteinuria |
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| CN101069722A (en) * | 2006-05-09 | 2007-11-14 | 广州康臣药业有限公司 | Chinese medicine composition for treating kidney disease syndrome and preparing method |
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| CN101259232A (en) * | 2008-04-25 | 2008-09-10 | 北京中泰天和科技有限公司 | Chinese medicinal composition for treating nephrotic syndrome and preparation thereof |
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