CN104258007A - Traditional Chinese medicine preparation for pig fattening and growth promotion and preparation method of traditional Chinese medicine preparation - Google Patents

Traditional Chinese medicine preparation for pig fattening and growth promotion and preparation method of traditional Chinese medicine preparation Download PDF

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CN104258007A
CN104258007A CN201410473800.5A CN201410473800A CN104258007A CN 104258007 A CN104258007 A CN 104258007A CN 201410473800 A CN201410473800 A CN 201410473800A CN 104258007 A CN104258007 A CN 104258007A
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CN104258007B (en
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马改云
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HENAN DEFANG BIOLOGICAL PHARMACEUTICAL Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives

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  • Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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Abstract

The invention belongs to the field of veterinary traditional Chinese medicine preparations and mainly relates to a traditional Chinese medicine preparation for pig fattening and growth promotion and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation comprises the following components in parts by weight: 5-10 parts of radix paeoniae alba, 5-10 parts of yeast polysaccharides, 5-10 parts of pine needle meal, 5-10 parts of empress tree leaves, 10-20 parts of folium artemisiae argyi, 10-20 parts of Chinese parsley, 5-10 parts of garlic, 5-10 parts of chili, 5-10 parts of pepper and 5-10 parts of enzyme production probiotics. The traditional Chinese medicine preparation has the effects of improving digestion, tonifying spleen, nourishing the stomach and promoting digestion function and can achieve the effects of fattening and promoting growth of pigs. Moreover, due to the unique effects of the traditional Chinese medicine, the immunity of the body can be improved, and the disease resistance is enhanced.

Description

A kind of pig that is used for is fattened somatotrophic Chinese medicine preparation and preparation method thereof
technical field
The invention belongs to veterinary Chinese medicine formulation art, relate generally to and a kind of to fatten somatotrophic Chinese medicine preparation and preparation method thereof for pig.
background technology
The pig farm somatotrophic additive types that is used for fattening gets more and more in recent years, how to make pig grow fast, becomes the problem that raiser urgently pays close attention to.
In order to solve pig farm pig poor growth, the unconspicuous present situation of benefit, some pig farm many employings western medicine antibiotics class feed additive, although somatotrophic effect of fattening can be played, but the drug residue caused is later Carnis Sus domestica to come into the market to hide some dangers for, easily cause again the drug resistance of similar drugs simultaneously, what bring pig farm is that overall immunity declines, and buries healthy hidden danger to whole pig farm.
For this reason, according to the pure natural of Chinese medicine, have no side effect, noresidue, feature without Drug resistance and its functional diversity, draw the advantage of traditional Chinese veterinary medicine, by the new technique of modern medicines research, in conjunction with the physiological characteristics of growing and fattening pigs, how to develop collection diseases prevention, fatten, growth-promoting be longer than one product be a research direction.
summary of the invention
The invention provides and a kind of to fatten somatotrophic Chinese medicine preparation and preparation method thereof for pig.
The present invention is by the following technical solutions:
A kind of pig that is used for is fattened somatotrophic Chinese medicine preparation, with parts by weight, it consists of: Radix Paeoniae Alba 5-10 part, zymosan 5-10 part, pine needle powder 5-10 part, Folium paulowniae 5-10 part, Folium Artemisiae Argyi 10-20 part, coriander 10-20 part, Bulbus Allii 5-10 part, Fructus Capsici 5-10 part, Fructus Piperis 5-10 part and product enzyme probiotics 5-10 part.
To fatten for the preparation of pig the method for somatotrophic Chinese medicine preparation, first Bulbus Allii, coriander are carried out drying; Get the Radix Paeoniae Alba, pine needle powder, Folium paulowniae, Folium Artemisiae Argyi, coriander, Bulbus Allii, Fructus Capsici, Fructus Piperis respectively after micronizing, with zymosan, produce enzyme probiotics and proportionally mix, obtain Chinese medicine preparation.
The temperature of preferred drying is 30-60 DEG C, and drying time is at least 30min.
The using method of Chinese medicine preparation of the present invention: for pig, every 500-1500g spice 500kg(0.1-0.3% Pitch-based sphere), mixed feeding, is used in conjunction 5-7 days.
In the present invention, the Radix Paeoniae Alba, has another name called Radix Paeoniae Alba, golden Radix Paeoniae, is the root of cohosh Radix Paeoniae, bitter, acid, is slightly cold, and returns liver, spleen channel, has suppressing the hyperactive liver pain relieving, the effect of the yin fluid astringing that nourishes blood, and cures mainly deficiecny of liver-YIN, deficiency-heat, dysentery stomachache, spasm of the limbs.
Zymosan is also called complex polysaccharide, and it has unique targeting, can directed purged body endotoxin, the phagocytic function simultaneously improving macrophage reaches more than 10 times, immune system is made to reach balance rapidly, without any side effects, effectively prevent the generation of various disease.The immune mechanism of zymosan is: 1, the propagation of stimulating animal body endolymph cell; 2, the macrophage in activating animals body, it is generally acknowledged that in body, reticuloendothelial system is under the stimulation of glucosan, produce the macrophage in a large number body's immunity played a crucial role, and macrophage is absorbed by phagocytosis, destroys and damages in purged body, pathogenic microorganism in old and feeble, dead own cells and intrusive body; 3, the ability that animal body produces natural killer cell is increased; 4, lure that animal produces nonspecific immunity to cause of disease into, improve survival rate; 5, maintain microecological balance and strengthen animal immunizing power, improve animal health condition, increase the adaptability of animal pessimal stimulation to external world.Zymosan is used for poultry following effect: 1, immunological enhancement; 2, disease-resistant growth-promoting effect: (1), by the adjustment to each organs of whole digestive system such as liver, gallbladder and intestinals, makes the Tiny ecosystem of digestive system be in the optimum state of balance, thus effectively prevents the generation of digestive system various diseases; (2) mannan can disturb enteric pathogenic bacteria determine grow, thus reduce animal intestinal pathogenic microorganism quantity as Salmonella and colibacillary quantity; 3, antioxidation: zymosan energy Promote immunity allelotaxis, scavenging free radicals, what the multiple difficult miscellaneous diseases of effectively preventing animal to cause due to free radical infringement, immunologic hypofunction etc., many reasons caused stress; 4, Detoxication: zymosan has anti-enterotoxin effect, and many escherichia coli can produce enterotoxin, seize the adsorption of other antibacterials and enteric epithelium dehydration can be caused too much, zymosan can make enterotoxin inactivation; Facts have proved zymosan for escherichia coli, Salmonella, gangrenosum acne, intractable enteritis and other bacillary intestinal diseases have good preventive and therapeutic effect, also effectively can reduce the morbidity risk rate of coccidiosis; 5, Nutrition: zymosan is the most direct source of nutrition in animal body, improve poultry growth performance, good intestinal environment makes feed nutrient fully absorb, it is round and smooth, fine and smooth that feces becomes, can not see indigested feed granules, feedstuff-meat ratio is significantly improved, and zymosan can obviously improve meat Egg Quality etc.
Pine needle powder, containing 18 seed amino acids, include 9 kinds of essential amino acids needed for animal, essential amino acids accounts for 54% of total amino acids.Therefore, pine needle powder adds in feedstuff, can improve the protein quality of feedstuff, supplements animal to amino acid whose needs.In pine needle powder, the content of macroelement potassium, calcium, magnesium is all higher than Semen Maydis seed, and calcium content is far away higher than soybean seed.Other trace element reaches more than 40 and plants, and rich content.The content of copper, ferrum, manganese, zinc is all higher than Semen Maydis seed and soybean seed, and wherein Zn content is 2 times of Semen sojae atricolor and Semen Maydis seed, and heavy metal and toxic element content seldom, all below limit amount, illustrate that pine needle powder is without toxicity, side effect.The most actively in composition contained by Folium Pini also the most important thing is vitamin moieties, and rank first with vitamin A.Contained vitamin A source---carotene in pine needle powder is more than 10 times of the carotene carotene content that (comprises vegetable, fruit, forage grass and leaves) in all edible plants, be Semen Maydis, nearly 100 times of bean cake carotenoid content.The quality standard that the quality index of the pine needle powder national standard that the former Soviet Union promulgates and domestic literature propose also is to determine its grade with the height of carotene carotene content.In addition, a large amount of vitamin Es and vitamin C etc. is contained in pine needle powder.Containing volatile oil, resin, chlorophyll in pine needle powder, also containing bioactive substances such as phytohormone, phytocide, UGFs (UGF), can detoxify parasite killing, suppresses harmful microbe growth and breeding in body, eliminate stagnation of QI due to dyspepsia, promote growth of animals or poultry.The dull and stereotyped bacteriostatic test of From Pineneedles of Pinus Massoniana Lamb powder is shown: From Pineneedles of Pinus Massoniana Lamb leaf to 6 kinds of microorganism antibacterial circle diameters at 8 ~ 16mm, show moderate bacteriostasis, to microorganism, there is bacteriostatic activity, wherein to pathogenic bacterium staphylococcus aureus, escherichia coli, all there is stronger bacteriostasis, can screen and originate as antibacterials.
Folium Artemisiae Argyi, the dried leaves of feverfew Chinese mugwort Artemisia argyi Levl. et Vant., containing volatile oil, bitter in the mouth, tepor, nontoxic, enter spleen, liver, kidney channel; To regulate the flow of vital energy blood, by cold-damp; Warming the meridian, hemostasis, antiabortive; Control trusted subordinate's cold type of pain, convulsion of having loose bowels, chronic dysentery, tells nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.Folium Artemisiae Argyi all has antibacterial action to 10 kinds of Gram-positive aerophils such as anthrax bacillus, Alpha-hemolytic streptococcus, B-Streptococcus hemolyticus, diphtheria corynebacterium, bacillus pseudodiphthericus, lung diplococcoid, staphylococcus aureus, Staphylococcus citreus, white Portugal Portugal coccus, bacillus subtilis in vitro, has the effects such as antifungal, function of gallbladder promoting, hemostasis, protection cardiovascular, antiallergic simultaneously.
Folium paulowniae is the leaf of goatweed Paulownia or royal paulownia, and bitter in the mouth is cold in nature, heat-clearing and toxic substances removing, hemostasia and detumescence; Folium paulowniae has antibacterial and antivirus action, function of relieving cough and calming asthma, has the significantly stable and effect such as cooling effect, antiinflammatory to cental system.
Coriander, has another name called Herba Coriandri, for Umbelliferae coriander belongs to annual herb plant, pungent, warm, returns lung, spleen channel; Have diaphoresis rash, removing stagnancy of indigested food and making QI downward, be amusing and in effect; Herba Coriandri is nutritious, and Herba Coriandri includes vitamin C, carotene, vitamin B1, B2 etc., simultaneously also containing abundant mineral, as calcium, ferrum, phosphorus, magnesium etc., also containing potassium malate etc. in Herba Coriandri.
Bulbus Allii belongs to Liliaceae Allium, has strong disinfecting, improves the effect of immunity, and can effectively suppress and kill the bacterial viruses such as the helicobacter pylori causing gastroenteropathy, remove the intestines and stomach noxious substance, stimulating gastrointestinal mucosa, promote appetite, accelerate digestion.
Fructus Capsici can promote fat metabolism, improves blood circulation, and stomach invigorating is aid digestion, and Fructus Capsici has stimulation to oral cavity and gastrointestinal, and energy strengthening gastrointestinal peristalsis, facilitating digestion liquid is secreted, and improves appetite, and can suppress enteral abnormal fermentation.
Fructus Piperis has another name called black river, is that the one of Piperaceae is bloomed liana, enters stomach, spleen, large intestine channel, can stomach invigorating feed, warming spleen and stomach for dispelling cold, pain relieving, Deficiency and coldness of spleen and stomach, vomiting, diarrhoea, and pungent is felt, the function that promotes appetite, improve digestion.
Produce enzyme probiotics, by bacillus subtilis, Bacillus licheniformis, lactobacillus, the metabolite of yeast and Clostridium butyricum takes the Tiny ecosystem joint product of composition as the leading factor, can the multiple digestive enzyme of product at organism metabolism, vitamin B group, organic acid and antibiotic substance, band can generate multiple unknown somatomedin etc., and enhance Intestinal Mucosal Immunization, there is prevention zoogenetic infection, promote growth of animal, improve animal immune, reduce food consumption, improve the important effect such as breeding environment and livestock products quality, the safety of alternative feeding antibiotic, efficiently, have no drug resistance, noresidue, free of contamination green bio-functional additive.Be characterized in: prevention drug resistance pathogen and mixed infection, improve food conversion ratio and reduce feed cost, improve fertility performance and meat, optimization of ecological environment and reduction environmental pollution.
The present invention's medicine used is according to the combination principle of Chinese medicine monarch, and the Radix Paeoniae Alba, Bulbus Allii, zymosan are monarch drug; Pine needle powder, Folium paulowniae, Folium Artemisiae Argyi are ministerial drug; Coriander, Fructus Capsici, Fructus Piperis are adjuvant drug; Producing enzyme probiotics for making medicine, playing effect of invigorating the stomach and promoting digestion, strengthening the spleen and nourishing the stomach digestion promoting altogether, not only can play the somatotrophic effect of weight gaining to pig, and due to the unique effect of Chinese medicine, the immunity of body can be improved simultaneously, thus strengthen resistance against diseases.Fructus Capsici in formula, Bulbus Allii and Fructus Piperis not only have the function of digestion promoting and weight gaining, also can be used as the flavoring agent of feedstuff simultaneously, improve feed intake, enhancing development, and be the pure Chinese medicinal preparation that noresidue has no drug resistance, safe and effective.
Detailed description of the invention
Below by way of enforcement, the present invention is described further, but protection scope of the present invention is not limited thereto.
Zymosan in embodiment, purchased from Huzhou Lang Shenxi Bioisystech Co., Ltd, produces enzyme probiotics and comes biological Engineering Co., Ltd purchased from Shandong Bora profit.The Radix Paeoniae Alba, Folium paulowniae, Folium Artemisiae Argyi, Fructus Capsici, Fructus Piperis are dry product.
Embodiment
To fatten somatotrophic Chinese medicine preparation for pig, with parts by weight, it consists of:
Being prepared as follows for pig somatotrophic Chinese medicine preparation of fattening in embodiment: first Bulbus Allii, coriander are carried out dry 30min at 60 DEG C; After the Radix Paeoniae Alba, pine needle powder, Folium paulowniae, Folium Artemisiae Argyi, coriander, Bulbus Allii, Fructus Capsici, Fructus Piperis are carried out micronizing respectively, add in mixer, add zymosan simultaneously, product enzyme probiotics is uniformly mixed 30 minutes, obtain Chinese medicine preparation of the present invention.
Effect experimental: the somatotrophic contrast test of Chinese medicine preparation weight gaining of the present invention
Carry out as follows:
(1) medicine and reagent
Test group 1-3, trial drug: the Chinese medicine preparation prepared by embodiment 1,2,3;
Matched group 1, control drug 1:12% Salinomycin pre-mixing agent (Hubei Ju Longtang biotechnology Development Co., Ltd)
Matched group 2, control drug 2:15% Chlortetracycline premix (Jinan Sheng Hong feed corporation,Ltd)
(2) test method
(1) EXPERIMENTAL DESIGN: select pig 100 in the health of parity, body weight is close, kind is identical about 50kg as experimental animal, to be divided into 5 groups at random, often organize 20, wherein 3 test group, 2 matched groups.
Test group 1, embodiment 1 product is by 0.1% Pitch-based sphere (every 500g spice 500kg) administration;
Test group 2, embodiment 2 product is by 0.2% Pitch-based sphere (every 1000g spice 500kg) administration;
Test group 3, embodiment 3 product is by 0.3% Pitch-based sphere (every 1500g spice 500kg) administration;
Matched group 1,1 ton of material adds control drug 1 330g;
Matched group 2,1 ton of material adds control drug 2 1000g.
Concrete grammar is: taking free choice feeding, epidemic prevention, control measures consistent with daily, was a test period with 15 days.
Basal diet is corn-soybean meal type daily ration, containing vitamin, trace element, lysine in additive premix, except test medication beyond the region of objective existence, not containing other medicines additive.
Observed and recorded project has: mainly comprise average feed consumption, daily gain, feed-weight ratio.
(2) results and analysis
Daily gain, feedstuff-meat ratio compare
As can be seen from the above table, test group average daily gain is 889g, improves 104g than matched group 1, improves 170g than matched group 2.Wherein test group 3 increase rate is maximum, and daily gain reaches 945g, improves 160g than matched group 1,226g is improved than matched group 2, per kilogram weightening finish feed consumption test 1,2,3 group is respectively 2.30,2.28,2.21, and all higher than the feed conversion rate of matched group 1 and 2, test group 3 feed conversion rate is the highest.

Claims (3)

1. to fatten somatotrophic Chinese medicine preparation for pig for one kind, it is characterized in that, with parts by weight, it consists of: Radix Paeoniae Alba 5-10 part, zymosan 5-10 part, pine needle powder 5-10 part, Folium paulowniae 5-10 part, Folium Artemisiae Argyi 10-20 part, coriander 10-20 part, Bulbus Allii 5-10 part, Fructus Capsici 5-10 part, Fructus Piperis 5-10 part and product enzyme probiotics 5-10 part.
2. prepare the method for somatotrophic Chinese medicine preparation of fattening for pig according to claim 1, it is characterized in that, first Bulbus Allii, coriander are carried out drying; Get the Radix Paeoniae Alba, pine needle powder, Folium paulowniae, Folium Artemisiae Argyi, coriander, Bulbus Allii, Fructus Capsici, Fructus Piperis respectively after micronizing, with zymosan, produce enzyme probiotics and proportionally mix, obtain Chinese medicine preparation.
3. preparation method as claimed in claim 2, is characterized in that, dry temperature is 30-60 DEG C, and drying time is at least 30min.
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104839506A (en) * 2015-06-05 2015-08-19 袁国防 Green pig feed additive
CN107594174A (en) * 2017-11-01 2018-01-19 何秀芬 A kind of Chinese medicine expelling parasite growth promotion pig feed additive and preparation method thereof
CN110859916A (en) * 2019-12-03 2020-03-06 六安恒佳生物科技有限公司 Toxin-expelling and detoxifying additive for fermented traditional Chinese medicine pigs and preparation method thereof

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