CN104257904A - Chinese medicinal preparation for lowering blood pressure - Google Patents
Chinese medicinal preparation for lowering blood pressure Download PDFInfo
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- CN104257904A CN104257904A CN201410576355.5A CN201410576355A CN104257904A CN 104257904 A CN104257904 A CN 104257904A CN 201410576355 A CN201410576355 A CN 201410576355A CN 104257904 A CN104257904 A CN 104257904A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 27
- 230000036772 blood pressure Effects 0.000 title claims abstract description 24
- 239000003814 drug Substances 0.000 claims abstract description 44
- 239000007788 liquid Substances 0.000 claims abstract description 12
- 238000009835 boiling Methods 0.000 claims abstract description 6
- 238000001914 filtration Methods 0.000 claims abstract description 6
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229940079593 drug Drugs 0.000 claims description 10
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 12
- 206010020772 Hypertension Diseases 0.000 abstract description 8
- 239000000463 material Substances 0.000 abstract description 4
- 241000512005 Alstonia Species 0.000 abstract description 2
- 239000002994 raw material Substances 0.000 abstract description 2
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- 206010008190 Cerebrovascular accident Diseases 0.000 description 2
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention discloses a Chinese medicinal preparation for lowering blood pressure. The Chinese medicinal preparation is prepared from the following Chinese medicinal materials in percentage by weight: 60 g of clerodendrum fortunatum, 15 g of japanese eupatorium herb root, 8 g of lygodium root, 4 g of Yunnan alstonia root, 4 g of hairy gapeleaf anemone and 3 g of dodonaea root. A preparation method comprises the following steps: placing the Chinese medicinal materials according to the weight percentage in a decocting appliance and adding 2,000 ml of purified water; soaking for half an hour and enabling the Chinese medicinal materials to be fully wetted for sufficient decoction of medicinal concoction; boiling with strong fire and then decocting with slow fire for an hour, and filtering to remove medicine residue and obtaining liquid Chinese medicine; heating and concentrating the liquid Chinese medicine to 1,000 ml to obtain the Chinese medicinal preparation. The Chinese medicinal preparation disclosed by the invention is used for treating hypertension; the purpose of good curative effect and no toxic or side effect can be achieved; besides, the adopted raw materials are low in price and easily obtained.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically refer to a kind of Chinese medicine preparation of blood pressure lowering.
Background technology
Hypertension a kind ofly continues to raise for the chronic disease of main manifestations with arteriotony, one of principal pathogenetic reason is due to human peripheral arteriolospasm, human peripheral small artery resistance is strengthened, thus cause blood pressure to increase, form hypertension, often cause the pathological changes of the vitals such as the heart, brain, kidney and occur corresponding consequence.Long-term hypertension can cause cardiovascular disease as myocardial infarction, coronary heart disease etc., can also cause renal arteriosclerosis, thus cause renal insufficiency, uremia etc.
At present, still western medicine is relied on to hypertensive treatment major part, though Western medicine can meet general blood pressure lowering requirement, also have obvious side effect.Because Western medicine blood pressure lowering is all based on blood vessel dilating, and blood vessel dies down at continuous process of expansion Elastic and hardens, and therefore makes the people of life-time service depressor easily cause sclerosis of blood vessels and break, and causes the disease such as cerebral vessels embolism, apoplexy.Therefore, Western medicine is not suitable for permanent use.Evident in efficacy, that side effect the is low Chinese patent medicine of research screening seems particularly necessary.
Summary of the invention
The object of the invention is exactly the defect in order to make up prior art, provides a kind of instant effect, evident in efficacy, side effect is low, the Chinese medicine preparation of blood pressure lowering that cost is low, realizes particular by following technical scheme:
A Chinese medicine preparation for blood pressure lowering, is made up of the Chinese crude drug of following weight: Herba Clerodendri fortunati 40 ~ 80g, Herba eupatorii japonici 10 ~ 20g, Radix et rhizoma lygodii 3 ~ 13g, Radix Alstoniae Yunnanensis 1 ~ 7g, Herba Anaphalidis Nepalensis 1 ~ 7g, Radix Dodonaeae Viscosae 1 ~ 5g.
Preferably, a kind of Chinese medicine preparation of blood pressure lowering, is made up of the Chinese crude drug of following weight: Herba Clerodendri fortunati 60g, Herba eupatorii japonici 15g, Radix et rhizoma lygodii 8g, Radix Alstoniae Yunnanensis 4g, Herba Anaphalidis Nepalensis 4g, Radix Dodonaeae Viscosae 3g.
The preparation method of the Chinese medicine preparation of above-mentioned blood pressure lowering is: first the Chinese crude drug of above-mentioned weight is put into drug-decocting appliance, adds pure water 2000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 1 hour, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 1000 milliliters, obtains the Chinese medicine preparation of blood pressure lowering.
Herba Clerodendri fortunati: [source] is the Herb of Verbenaceae Fructus Seu Herba Pubescentis.[function cures mainly] clearing and antitussive; Removing toxic substances and promoting subsidence of swelling.Main pulmonary tuberculosis cough; Osteopyrexia and fever; Laryngopharynx swelling and pain; Traumatic injury; Furuncle and phyma furuncle.
Herba eupatorii japonici: the herb that [source] is feverfew mountain orchid or root.[function cures mainly] delivers cold expelling, saturating measles.Control proctoptosis, measles without adequate eruption, lumbago due to cold-damp, cough due to wind and cold.
Radix et rhizoma lygodii: [source] is the root and rhizome of Lygodiaceae plant Spora Lygodii.[function cures mainly] heat-clearing and toxic substances removing, inducing diuresis and reducing edema.Control pneumonia, encephalitis b, acute gastroenteritis, icterohepatitis, damp and hot generalized edema with distention of the chest and abdomen, gonorrhea.
Radix Alstoniae Yunnanensis: [source] is the root of apocynaceae plant alstonia yonnanensis.[function cures mainly] be " Guangxi Chinese medicinal herbal " 1.: " externally used detumescence controls local red and swollen.Blood pressure lowering again." 2. " Guangxi book on Chinese herbal medicine a collection of selected materials ": " heat-clearing and toxic substances removing, preventing the attack (or recurrence) of malaria, reducing swelling and alleviating pain.Treating malaria disease, cold, fever, cough due to lung-heat, laryngopharynx swelling and pain, stomatitis.”
Herba Anaphalidis Nepalensis: [source] is the fragrant blue or green herb of feverfew Nepal.[function cures mainly] refreshing and detoxicating, puts down and coughs Dingchuan.Cure cold cough, acute and chronic tracheitis, rheumatic skelalgia, hypertension.
Radix Dodonaeae Viscosae: [source] is the root of sapindaceous plant aalii.The whole year can adopt.[function cures mainly] subduing swelling and detoxicating.
The instructions of taking of above-mentioned Chinese medicine preparation is: one day twice, sooner or later respectively once, each serving with 20 ~ 50ml, within 30 days, is a course for the treatment of.
The present invention is made up of Chinese medicine, has suppressing the hyperactive liver to relieve the wind syndrome, alleviates effect of periphery arteriolospasm, thus the QI and blood of containing was declined, and reaches the object of blood pressure lowering.There is good effect, instant effect and the advantage had no side effect in the Chinese medicine preparation of blood pressure lowering of the present invention, and raw materials used medicine is all cheap and easy to get.
detailed description of the invention:
Below in conjunction with embodiment and case, the present invention is further illustrated.
Embodiment 1:
Take Herba Clerodendri fortunati 40g, Herba eupatorii japonici 20g, Radix et rhizoma lygodii 3g, Radix Alstoniae Yunnanensis 7g, Herba Anaphalidis Nepalensis 1g, Radix Dodonaeae Viscosae 5g put into drug-decocting appliance, add pure water 2000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 1 hour, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 1000 milliliters, obtains the Chinese medicine preparation of blood pressure lowering.
Embodiment 2:
Take Herba Clerodendri fortunati 80g, Herba eupatorii japonici 10g, Radix et rhizoma lygodii 13g, Radix Alstoniae Yunnanensis 1g, Herba Anaphalidis Nepalensis 7g, Radix Dodonaeae Viscosae 1g put into drug-decocting appliance, add pure water 2000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 1 hour, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 1000 milliliters, obtains the Chinese medicine preparation of blood pressure lowering.
Embodiment 3:
Take Herba Clerodendri fortunati 60g, Herba eupatorii japonici 15g, Radix et rhizoma lygodii 8g, Radix Alstoniae Yunnanensis 4g, Herba Anaphalidis Nepalensis 4g, Radix Dodonaeae Viscosae 3g put into drug-decocting appliance, add pure water 2000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 1 hour, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 1000 milliliters, obtains the Chinese medicine preparation of blood pressure lowering.
Clinical testing data:
For checking therapeutic effect of the present invention, choose the routine patients with hypertension of Anqing, Anhui Province Qianshan County 99, the range of age 42 ~ 70 years old, 58 years old mean age, wherein male 50 example, women 49 example.99 routine patient's stochastic averagina are divided into three groups, are respectively treatment group 1, treatment group 2 and treatment group 3, often organize 33 routine patients.Diagnostic criteria: systolic pressure is equal to or higher than 160mmHg(21.3kPa), diastolic pressure is equal to or higher than 95mmHg(12.721.3kPa), both have 1 through examining, and can make a definite diagnosis.
Therapeutic Method:
Treatment group 1 adopts the Chinese medicine for lowering blood pressure preparation of the embodiment of the present invention 1 to treat, one day twice, sooner or later each once, each serving with 30ml; Treatment group 2 adopts the Chinese medicine for lowering blood pressure preparation of the embodiment of the present invention 2 to treat, one day twice, sooner or later each once, each serving with 30ml; Treatment group 3 adopts the Chinese medicine for lowering blood pressure preparation of the embodiment of the present invention 3 to treat, one day twice, sooner or later each once, each serving with 30ml; Above three components is treated 30 days not continuously.
Criterion of therapeutical effect:
Effective: 1. diastolic pressure decline 10mmHg(1.3kPa) more than, and reach normal range; Though 2. diastolic pressure is normally not near, declined 20 mmHg(2.7kPa) or more, wherein 1 must be possessed;
Effective: 1. diastolic pressure declines not as good as 10mmHg(1.3kPa), but reach normal range; 2. diastolic pressure comparatively treats front 10 ~ 19 mmHg(1.3 ~ 2.5kPa that decline), but do not reach normal range; 3. systolic pressure comparatively treats front 30 mmHg(4kPa that decline); Wherein 1 must be possessed;
Invalid: not reach above standard.
Therapeutic effect:
Treatment group 1: effective 14 examples, account for 42.4%; Effective 14 examples, account for 42.4%; Invalid 5 examples; Total effective rate 84.8%;
Treatment group 2: effective 17 examples, account for 51.5%; Effective 15 examples, account for 45.5%; Invalid 1 example; Total effective rate 97%;
Treatment group 3: effective 29 examples, account for 87.9%; Effective 4 examples, account for 12.1%; Invalid 0 example; Total effective rate 100%.
As can be seen from above-mentioned therapeutic outcome, the Chinese medicine preparation of the present invention's three embodiments all has good blood pressure reduction effect, and total effective rate reaches more than 84.8%, wherein, the obvious effective rate of the Chinese medicine preparation of embodiment 3 is the highest, reaches 87.9%, achieves beyond thought effect.
After treatment, carry out Effect of follow-up visit by telephone to whole 99 routine patients above, continue half a year, do not find that the case such as cerebral vessels embolism, apoplexy appears in an example, hypertension relapse rate is less than 7%.
Claims (1)
1. a Chinese medicine preparation for blood pressure lowering, is characterized in that: be made up of the Chinese crude drug of following weight: Herba Clerodendri fortunati 60g, Herba eupatorii japonici 15g, Radix et rhizoma lygodii 8g, Radix Alstoniae Yunnanensis 4g, Herba Anaphalidis Nepalensis 4g, Radix Dodonaeae Viscosae 3g; Preparation method is: first the Chinese crude drug of above-mentioned weight is put into drug-decocting appliance, adds pure water 2000 milliliters; Soak half an hour, make Chinese crude drug fully moistening, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead and decoct 1 hour, cross after filtering medicinal residues and obtain herb liquid; Described herb liquid heating is concentrated into 1000 milliliters, obtains the Chinese medicine preparation of blood pressure lowering.
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| CN201410576355.5A CN104257904A (en) | 2014-10-26 | 2014-10-26 | Chinese medicinal preparation for lowering blood pressure |
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| CN201410576355.5A CN104257904A (en) | 2014-10-26 | 2014-10-26 | Chinese medicinal preparation for lowering blood pressure |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104840605A (en) * | 2015-05-26 | 2015-08-19 | 合肥丰瑞隆生物科技有限公司 | Antihypertensive traditional Chinese medicine |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104840605A (en) * | 2015-05-26 | 2015-08-19 | 合肥丰瑞隆生物科技有限公司 | Antihypertensive traditional Chinese medicine |
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