CN105125963A - Medicine for treating non-small cell lung cancer postoperative stagnant heat obstructive pulmonary syndrome and preparation and use method thereof - Google Patents
Medicine for treating non-small cell lung cancer postoperative stagnant heat obstructive pulmonary syndrome and preparation and use method thereof Download PDFInfo
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Abstract
The invention provides medicine for treating non-small cell lung cancer postoperative stagnant heat obstructive pulmonary syndrome and a preparation and use method thereof. The medicine is prepared from, by weight, 40-70 parts of rhizoma phragmitis, 20-55 parts of coix seed, 16-32 parts of wax guard seed, 10-15 parts of peach seed, 15-40 parts of herba houttuyniae, 10-16 parts of bryozoatum, 10-30 parts of honeysuckle and 5-20 parts of phillyrin. The raw materials are added to reed rhizorme decoction to be decocted into the liquid medicine. The defects that in the prior art, only symptoms are treated instead of root causes and the effect is not ideal are overcome, the obtained medicine has a good effect on treating non-small cell lung cancer postoperative stagnant heat obstructive pulmonary syndrome.
Description
Technical field
The present invention relates to Chinese medicine technical field, particularly relate to a kind of postoperative rehabilitation medicine, specifically refer to a kind of medicine, preparation method and the using method for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung and demonstrate,proving.
Background technology
As everyone knows, the postoperative common clinical manifestation of pulmonary's nonsmall-cell lung cancer is: aversion to cold, heating, cough, cough up yellow sticky expectorant, chest pain, cough, and chest pain increases the weight of, it is unfavorable to change one's position, red tongue, yellow fur are thick, rolling pulse.These performances belong to the stagnant heat resistance lung card of the traditional Chinese medical science, but, for this disease, there is no effective ways symptomatic treatment at present.
Summary of the invention
The technical problem to be solved in the present invention is for the weak point existing for prior art, a kind of medicine for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card is provided, overcome in prior art cure the symptoms, not the disease, defect that effect is undesirable, adopt gained Drug therapy nonsmall-cell lung cancer of the present invention postoperative stagnant heat resistance lung card, therapeutic effect is good.
The present invention, for solving above technical problem, provides following technical scheme:
A kind of medicine for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card, calculate by weight, comprise Rhizoma Phragmitis 40 ~ 70 parts, Semen Coicis 20 ~ 55 parts, Semen Benincasae 16 ~ 32 parts, 10 ~ 15 parts, Semen Persicae, Herba Houttuyniae 15 ~ 40 parts, Pumex 10 ~ 16 parts, Flos Lonicerae 10 ~ 30 parts and Fructus Forsythiae 5 ~ 20 parts, add weijing decoction and decoct patent medicine soup.
A kind of medicine for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card, calculate by weight, also comprise Flos Inulae 0.5 ~ 5 part, 8 ~ 16 parts, Semen Armeniacae Amarum, cortex trichosanthis 10 ~ 15 parts, Radix Rubiae 3 ~ 12 parts, Cortex Moutan 4 ~ 8 parts, Radix Salviae Miltiorrhizae 9 ~ 19 parts, Fructus Aurantii 10 ~ 30 parts, Exocarpium Citri Rubrum 10 ~ 40 parts, loose 3 ~ 10 parts of Concha Meretricis Seu Cyclinae, Rhizoma Imperatae 7 ~ 12 parts, Radix Glycyrrhizae 5 ~ 19 parts, Bulbus Fritillariae Thunbergii 5 ~ 7 parts, Fel Serpentis 6 ~ 9 parts, Fractus Eriobotryae 6 ~ 9 parts, Radix Adenophorae (Radix Glehniae) 10 ~ 20 parts, Radix Ophiopogonis 10 ~ 18 parts, raw Rhizoma Polygonati Odorati 12 ~ 17 parts, Radix Trichosanthis 10 ~ 23 parts, 8 ~ 20 parts, Seem Lablab Album, 2 ~ 8 parts, Folium Mori, Pupa bombycis 6 ~ 12 parts, Herba Dendrobii 10 ~ 23 parts, Flos Farfarae 7 ~ 9 parts, Fructus Schisandrae Chinensis 8 ~ 12 parts, Fgopyrum dibotrys Hara 12 ~ 20 parts, the subcutaneous mucus of Cupressaceae 5 ~ 9 parts, Cacumen Cupressi 10 ~ 12 parts, Fructus Citri Sarcodactylis 7 ~ 9 parts, Radix Bupleuri 12 ~ 16 parts, 7 ~ 23 parts, fresh Folium Bambusae, Endothelium Corneum Gigeriae Galli 12 ~ 15 parts, Radix Angelicae Sinensis 8 ~ 15 parts, 5 ~ 7 parts, Poria, Cortex Magnoliae Officinalis 9 ~ 18 parts, Herba Eupatorii 10 ~ 18 parts.
As preferably, a kind of medicine for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card, calculate by weight, comprise Rhizoma Phragmitis 60 parts, Semen Coicis 30 parts, Semen Benincasae 24 parts, 12 parts, Semen Persicae, Herba Houttuyniae 30 parts, Pumex 12 parts, Flos Lonicerae 20 parts, Fructus Forsythiae 18 parts, Flos Inulae 2 parts, 10 parts, Semen Armeniacae Amarum, cortex trichosanthis 20 parts, Radix Rubiae 8 parts, Cortex Moutan 6 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Aurantii 20 parts, Exocarpium Citri Rubrum 30 parts, loose 5 parts of Concha Meretricis Seu Cyclinae, Rhizoma Imperatae 9 parts, Radix Glycyrrhizae 10 parts, Bulbus Fritillariae Cirrhosae 6 parts, Fel Serpentis 7 parts, Fractus Eriobotryae 8 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Ophiopogonis 14 parts, raw Rhizoma Polygonati Odorati 14.5 parts, Radix Trichosanthis 18 parts, 17 parts, Seem Lablab Album, 6 parts, Folium Mori, Pupa bombycis 8 parts, Herba Dendrobii 17 parts, Flos Farfarae 8 parts, Fructus Schisandrae Chinensis 10 parts, Fgopyrum dibotrys Hara 17 parts, the subcutaneous mucus of Cupressaceae 6 parts, Cacumen Cupressi 11 parts, Fructus Citri Sarcodactylis 8 parts, Radix Bupleuri 14 parts, 17 parts, fresh Folium Bambusae, Endothelium Corneum Gigeriae Galli 13 parts, Radix Angelicae Sinensis 12 parts, 8 parts, Poria, Cortex Magnoliae Officinalis 12 parts, Herba Eupatorii 16 parts, add weijing decoction and decoct patent medicine soup.
A kind of process for preparing medicine for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card: the decoction comprising medicine.
Described drug decocting step is:
(1) by Rhizoma Phragmitis 40 ~ 70 parts, Semen Coicis 20 ~ 55 parts, Semen Benincasae 16 ~ 32 parts, 10 ~ 15 parts, Semen Persicae, Herba Houttuyniae 15 ~ 40 parts, Pumex 10 ~ 16 parts, Flos Lonicerae 10 ~ 30 parts and Fructus Forsythiae 5 ~ 20 parts are put into and are decocted vessel, soak 15 ~ 2 minutes to decocting the mixed solution adding clear water and DBDMH in vessel, wherein clear water is 100: 0.2 ~ 1 with DBDMH mixed weight ratio, then the water decocted in vessel is outwelled, again utilize aseptic clear water to rinse medicine 2 ~ 3 times, and the water of cleaning is outwelled;
(2) in decoction vessel, add weijing decoction 100 parts, spacious lid utilizes intense fire to decoct to latter 8 ~ 10 minutes of boiling; Right pot cover decocts, and changes intense fire into slow fire simultaneously, and makes intrinsic pressure the trying hard to keep of decoction vessel hold 66 ~ 72KPa, continues this pressure and decocts 3 ~ 5 minutes;
(3) in time decocting vessel inside residue 1L medicine soup, heating is stopped, pressure to be released, open wide pot cover, when medicine soup temperature is more than 80 DEG C, utilize steel spoon and strainer extruding medicine, medicine soup in medicine is all squeezed out, completes being separated of medicine soup and medicinal residues.
As preferably, described weijing decoction is added water 100 parts by Rhizoma Phragmitis 30 ~ 60 parts, Semen Coicis 20 ~ 40 parts, 5 ~ 16 parts, Semen Persicae, Rhizoma Phragmitis 15 ~ 18 parts and Semen Benincasae 17 ~ 23 parts and decocts boiling through intense fire, and after boiling, add 20 parts of water continue slow fire boiling, heating is stopped, by stand-by for 100 parts of weijing decoction coolings of making after filtering medicinal residues after residue 100 parts of medicine soup bodies.
Promote that the using method of the medicine of nonsmall-cell lung cancer post-operative recovery is as follows: a when medicine soup is cooled to 30 ~ 50 DEG C, a point morning and evening takes for twice, each 0.5L.
Then isolated medicinal residues are loaded gunnysack, and medicinal residues temperature at 43 ~ 60 DEG C time carry out pulmonary's external application, partner treatment for patient, external application is half an hour before and after medication, until after medication half an hour terminate.
The clinical traditional Chinese medical science is observed, and the postoperative common clinical manifestation of pulmonary's nonsmall-cell lung cancer is: aversion to cold, heating, and cough, cough up yellow sticky expectorant, chest pain, coughs, and chest pain increases the weight of, and changes one's position unfavorable, red tongue, and yellow fur is thick, rolling pulse.These performances belong to the stagnant heat resistance lung card of the traditional Chinese medical science.
Utilize the medicine prepared by the present invention, there is removing heat from the lung and dissipating phlegm, removing blood stasis evacuation of pus, clearing away heat-damp and promoting diuresis, heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, effect of declaring smooth QI and blood, dispersing swelling and dissipating binds, loose blood agglomeration gas poly-, loose the swelling of the hot clearing away phlegm blood stasis dispelling of pulmonary is disappeared, the bright symptom alleviating patient of energy, promote the healing of post-surgical trauma tissue, be conducive to postoperative rehabilitation, show as stagnant heat resistance lung card person for pulmonary carcinoma is postoperative, with rather verify.By active drug reasonable formula, have complementary advantages, evident in efficacy, effective percentage reaches more than 99%.
Use medicine of the present invention, drug administration on time, the pulse frequency of patient medication after 3 days is 81-99 beat/min, respiratory frequency is 18-12 beat/min, cough and expectoration is 10-18ml/ day, and chest pain degree is II degree moderate pain, and after movable, pulse frequency is 92-115 beat/min, Hb numerical value is 110-128g/l, and leukocyte count is 8-13 × 10
9/ l;
Drug administration on time, the pulse frequency of patient medication after 3 days is 60-90 beat/min, and respiratory frequency is 16 ~ 20 beats/min, and cough and expectoration is nothing, chest pain degree be O degree not bitterly, after movable, pulse frequency is 60-100 beat/min, Hb numerical value is 120-140g/l, and leukocyte count is 4-10 × 10
9/ l.
Detailed description of the invention
For ease of illustrating, below a kind of medicine, preparation method and using method for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card of the present invention is elaborated.
Embodiment 1:
A kind of medicine for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card, calculate by weight, comprise Rhizoma Phragmitis 60 parts, Semen Coicis 30 parts, Semen Benincasae 24 parts, 12 parts, Semen Persicae, Herba Houttuyniae 30 parts, Pumex 12 parts, Flos Lonicerae 20 parts and Fructus Forsythiae 18 parts, add weijing decoction and decoct patent medicine soup.
A kind of process for preparing medicine for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card: the decoction comprising medicine.
Described drug decocting step is:
(1) by Rhizoma Phragmitis 60 parts, Semen Coicis 30 parts, Semen Benincasae 24 parts, 12 parts, Semen Persicae, Herba Houttuyniae 30 parts, Pumex 12 parts, Flos Lonicerae 20 parts and Fructus Forsythiae 18 parts are put into and are decocted vessel, soak 15 ~ 2 minutes to decocting the mixed solution adding clear water and DBDMH in vessel, wherein clear water is 100: 0.2 ~ 1 with DBDMH mixed weight ratio, then the water decocted in vessel is outwelled, again utilize aseptic clear water to rinse medicine 2 ~ 3 times, and the water of cleaning is outwelled;
(2) in decoction vessel, add weijing decoction 100 parts, spacious lid utilizes intense fire to decoct to latter 8 ~ 10 minutes of boiling; Right pot cover decocts, and changes intense fire into slow fire simultaneously, and makes intrinsic pressure the trying hard to keep of decoction vessel hold 66 ~ 72KPa, continues this pressure and decocts 3 ~ 5 minutes;
(3) in time decocting vessel inside residue 1L medicine soup, heating is stopped, pressure to be released, open wide pot cover, when medicine soup temperature is more than 80 DEG C, utilize steel spoon and strainer extruding medicine, medicine soup in medicine is all squeezed out, completes being separated of medicine soup and medicinal residues.
Described weijing decoction is added water 100 parts by Rhizoma Phragmitis 40 parts, Semen Coicis 30 parts, 12 parts, Semen Persicae, Rhizoma Phragmitis 16 parts and Semen Benincasae 19 parts and decocts boiling through intense fire, and after boiling, add 20 parts of water continue slow fire boiling, heating is stopped, by stand-by for 100 parts of weijing decoction coolings of making after filtering medicinal residues after residue 100 parts of medicine soup bodies.
Promote that the using method of the medicine of nonsmall-cell lung cancer post-operative recovery is as follows: a when medicine soup is cooled to 30 ~ 50 DEG C, a point morning and evening takes for twice, each 0.5L.
Then isolated medicinal residues are loaded gunnysack, and medicinal residues temperature at 43 ~ 60 DEG C time carry out pulmonary's external application, partner treatment for patient, external application is half an hour before and after medication, until after medication half an hour terminate.
Embodiment 2:
A kind of medicine for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card, calculate by weight, comprise Rhizoma Phragmitis 60 parts, Semen Coicis 30 parts, Semen Benincasae 24 parts, 12 parts, Semen Persicae, Herba Houttuyniae 30 parts, Pumex 12 parts, Flos Lonicerae 20 parts, Fructus Forsythiae 18 parts, Flos Inulae 2 parts, 10 parts, Semen Armeniacae Amarum, cortex trichosanthis 20 parts, Radix Rubiae 8 parts, Cortex Moutan 6 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Aurantii 20 parts, Exocarpium Citri Rubrum 30 parts, loose 5 parts of Concha Meretricis Seu Cyclinae, Rhizoma Imperatae 9 parts, Radix Glycyrrhizae 10 parts, Bulbus Fritillariae Cirrhosae 6 parts, Fel Serpentis 7 parts, Fractus Eriobotryae 8 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Ophiopogonis 14 parts, raw Rhizoma Polygonati Odorati 14.5 parts, Radix Trichosanthis 18 parts, 17 parts, Seem Lablab Album, 6 parts, Folium Mori, Pupa bombycis 8 parts, Herba Dendrobii 17 parts, Flos Farfarae 8 parts, Fructus Schisandrae Chinensis 10 parts, Fgopyrum dibotrys Hara 17 parts, the subcutaneous mucus of Cupressaceae 6 parts, Cacumen Cupressi 11 parts, Fructus Citri Sarcodactylis 8 parts, Radix Bupleuri 14 parts, 17 parts, fresh Folium Bambusae, Endothelium Corneum Gigeriae Galli 13 parts, Radix Angelicae Sinensis 12 parts, 8 parts, Poria, Cortex Magnoliae Officinalis 12 parts and Herba Eupatorii 16 parts, add weijing decoction and decoct patent medicine soup.
A kind of process for preparing medicine for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card: the decoction comprising medicine.
Described drug decocting step is:
(1) by Rhizoma Phragmitis 60 parts, Semen Coicis 30 parts, Semen Benincasae 24 parts, 12 parts, Semen Persicae, Herba Houttuyniae 30 parts, Pumex 12 parts, Flos Lonicerae 20 parts, Fructus Forsythiae 18 parts, Flos Inulae 2 parts, 10 parts, Semen Armeniacae Amarum, cortex trichosanthis 20 parts, Radix Rubiae 8 parts, Cortex Moutan 6 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Aurantii 20 parts, Exocarpium Citri Rubrum 30 parts, loose 5 parts of Concha Meretricis Seu Cyclinae, Rhizoma Imperatae 9 parts, Radix Glycyrrhizae 10 parts, Bulbus Fritillariae Cirrhosae 6 parts, Fel Serpentis 7 parts, Fractus Eriobotryae 8 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Ophiopogonis 14 parts, raw Rhizoma Polygonati Odorati 14.5 parts, Radix Trichosanthis 18 parts, 17 parts, Seem Lablab Album, 6 parts, Folium Mori, Pupa bombycis 8 parts, Herba Dendrobii 17 parts, Flos Farfarae 8 parts, Fructus Schisandrae Chinensis 10 parts, Fgopyrum dibotrys Hara 17 parts, the subcutaneous mucus of Cupressaceae 6 parts, Cacumen Cupressi 11 parts, Fructus Citri Sarcodactylis 8 parts, Radix Bupleuri 14 parts, 17 parts, fresh Folium Bambusae, Endothelium Corneum Gigeriae Galli 13 parts, Radix Angelicae Sinensis 12 parts, 8 parts, Poria, Cortex Magnoliae Officinalis 12 parts and Herba Eupatorii 16 parts are put into and decoct vessel, soak 15 ~ 2 minutes to decocting the mixed solution adding clear water and DBDMH in vessel,
Wherein clear water is 100: 0.2 ~ 1 with DBDMH mixed weight ratio, is then outwelled by the water decocted in vessel, again utilizes aseptic clear water to rinse medicine 2 ~ 3 times, and is outwelled by the water of cleaning;
(2) in decoction vessel, add weijing decoction 100 parts, spacious lid utilizes intense fire to decoct to latter 8 ~ 10 minutes of boiling; Right pot cover decocts, and changes intense fire into slow fire simultaneously, and makes intrinsic pressure the trying hard to keep of decoction vessel hold 66 ~ 72KPa, continues this pressure and decocts 3 ~ 5 minutes;
(3) in time decocting vessel inside residue 1L medicine soup, heating is stopped, pressure to be released, open wide pot cover, when medicine soup temperature is more than 80 DEG C, utilize steel spoon and strainer extruding medicine, medicine soup in medicine is all squeezed out, completes being separated of medicine soup and medicinal residues.
Described weijing decoction is added water 100 parts by Rhizoma Phragmitis 40 parts, Semen Coicis 30 parts, 12 parts, Semen Persicae, Rhizoma Phragmitis 16 parts and Semen Benincasae 19 parts and decocts boiling through intense fire;
And after boiling, add 20 parts of water continue slow fire boiling, after residue 100 parts of medicine soup bodies, stop heating, by stand-by for 100 parts of weijing decoctions coolings of making after filtering medicinal residues.
Promote that the using method of the medicine of nonsmall-cell lung cancer post-operative recovery is as follows: a when medicine soup is cooled to 30 ~ 50 DEG C, a point morning and evening takes for twice, each 0.5L.
Then isolated medicinal residues are loaded gunnysack, and medicinal residues temperature at 43 ~ 60 DEG C time carry out pulmonary's external application, partner treatment for patient, external application is half an hour before and after medication, until after medication half an hour terminate.
Embodiment 3:
A kind of medicine for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card, calculate by weight, comprise Rhizoma Phragmitis 40 parts, Semen Coicis 20 parts, Semen Benincasae 16 parts, 10 parts, Semen Persicae, Herba Houttuyniae 15 parts, Pumex 10 parts, Flos Lonicerae 10 parts, Fructus Forsythiae 5 parts, Flos Inulae 0.5 part, 8 parts, Semen Armeniacae Amarum, cortex trichosanthis 10 parts, Radix Rubiae 3 parts, Cortex Moutan 4 parts, Radix Salviae Miltiorrhizae 9 parts, Fructus Aurantii 10 parts, Exocarpium Citri Rubrum 10 parts, loose 3 parts of Concha Meretricis Seu Cyclinae, Rhizoma Imperatae 7 parts, Radix Glycyrrhizae 5 parts, Bulbus Fritillariae Thunbergii 5 parts, Fel Serpentis 6 parts, Fractus Eriobotryae 6 parts, Radix Adenophorae (Radix Glehniae) 10 parts, Radix Ophiopogonis 10 parts, raw Rhizoma Polygonati Odorati 12 parts, Radix Trichosanthis 10 parts, 8 parts, Seem Lablab Album, 2 parts, Folium Mori, Pupa bombycis 6 parts, Herba Dendrobii 10 parts, Flos Farfarae 7 parts, Fructus Schisandrae Chinensis 8 parts, Fgopyrum dibotrys Hara 12 parts, the subcutaneous mucus of Cupressaceae 5 parts, Cacumen Cupressi 10 parts, Fructus Citri Sarcodactylis 7 parts, Radix Bupleuri 12 parts, 7 parts, fresh Folium Bambusae, Endothelium Corneum Gigeriae Galli 12 parts, Radix Angelicae Sinensis 8 parts, 5 parts, Poria, Cortex Magnoliae Officinalis 9 parts and Herba Eupatorii 10 parts, add weijing decoction and decoct patent medicine soup.
The drug ratio of the treatment nonsmall-cell lung cancer provided in the present embodiment 3 postoperative stagnant heat resistance lung card is provided, then utilizes decocting method identical with embodiment 2 to carry out the decoction of medicine and using method is taken.
Embodiment 4:
A kind of medicine for the treatment of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card, calculate by weight, comprise Rhizoma Phragmitis 70 parts, Semen Coicis 55 parts, Semen Benincasae 32 parts, 15 parts, Semen Persicae, Herba Houttuyniae 40 parts, Pumex 16 parts, Flos Lonicerae 30 parts, Fructus Forsythiae 20 parts, Flos Inulae 5 parts, 16 parts, Semen Armeniacae Amarum, cortex trichosanthis 15 parts, Radix Rubiae 12 parts, Cortex Moutan 8 parts, Radix Salviae Miltiorrhizae 19 parts, Fructus Aurantii 30 parts, Exocarpium Citri Rubrum 40 parts, loose 10 parts of Concha Meretricis Seu Cyclinae, Rhizoma Imperatae 12 parts, Radix Glycyrrhizae 19 parts, Bulbus Fritillariae Thunbergii 7 parts, Fel Serpentis 9 parts, Fractus Eriobotryae 9 parts, Radix Adenophorae (Radix Glehniae) 20 parts, Radix Ophiopogonis 18 parts, raw Rhizoma Polygonati Odorati 17 parts, Radix Trichosanthis 23 parts, 20 parts, Seem Lablab Album, 8 parts, Folium Mori, Pupa bombycis 12 parts, Herba Dendrobii 23 parts, Flos Farfarae 9 parts, Fructus Schisandrae Chinensis 12 parts, Fgopyrum dibotrys Hara 20 parts, the subcutaneous mucus of Cupressaceae 9 parts, Cacumen Cupressi 12 parts, Fructus Citri Sarcodactylis 9 parts, Radix Bupleuri 16 parts, 23 parts, fresh Folium Bambusae, Endothelium Corneum Gigeriae Galli 15 parts, Radix Angelicae Sinensis 15 parts, 7 parts, Poria, Cortex Magnoliae Officinalis 18 parts, Herba Eupatorii 18 parts, add weijing decoction and decoct patent medicine soup.
The drug ratio of the treatment nonsmall-cell lung cancer provided in the present embodiment 4 postoperative stagnant heat resistance lung card is provided, then utilizes decocting method identical with embodiment 2 to carry out the decoction of medicine and using method is taken.
Pass through the clinical application to above-described embodiment 1 ~ 4 and analysis, the patient choosing 120 equal diseases carries out clinical trial, wherein often organize 30 patients, take embodiment 1, embodiment 2, embodiment 3 and the medicine prepared by embodiment 4 after surgery respectively, and carry out clinical application tracking, make a record;
After treatment in a week, integrate the data of 120 patients, draw mean values, specifically as shown in table 1.
Table 1:
Through to the medicine prepared by above-described embodiment 1 ~ 4, and the use in clinical, data collection and final analysis, as seen from the table, wherein the Clinical practice effect of embodiment 3 and embodiment 4 is effective not as the Clinical practice of embodiment 2; Embodiment 1 is compared with embodiment 3,4, and the result of use of embodiment 3,4 is better than embodiment 1.
Comprehensive analysis, the result of use of embodiment 2 is best, with a kind of embodiment of optimum.
In the above-described embodiments, preferred forms of the present invention is described, obviously, under inventive concept of the present invention, still can make a lot of change.At this, should illustrate, any change made under inventive concept of the present invention all will fall within the scope of protection of the present invention.
Claims (9)
1. treat the medicine of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card, it is characterized in that: calculate by weight, comprise Rhizoma Phragmitis 40 ~ 70 parts, Semen Coicis 20 ~ 55 parts, Semen Benincasae 16 ~ 32 parts, 10 ~ 15 parts, Semen Persicae, Herba Houttuyniae 15 ~ 40 parts, Pumex 10 ~ 16 parts, Flos Lonicerae 10 ~ 30 parts and Fructus Forsythiae 5 ~ 20 parts, add weijing decoction and decoct patent medicine soup.
2. the medicine for the treatment of nonsmall-cell lung cancer according to claim 1 postoperative stagnant heat resistance lung card, it is characterized in that: calculate by weight, also comprise Flos Inulae 0.5 ~ 5 part, 8 ~ 16 parts, Semen Armeniacae Amarum, cortex trichosanthis 10 ~ 15 parts, Radix Rubiae 3 ~ 12 parts, Cortex Moutan 4 ~ 8 parts, Radix Salviae Miltiorrhizae 9 ~ 19 parts, Fructus Aurantii 10 ~ 30 parts, Exocarpium Citri Rubrum 10 ~ 40 parts, loose 3 ~ 10 parts of Concha Meretricis Seu Cyclinae, Rhizoma Imperatae 7 ~ 12 parts, Radix Glycyrrhizae 5 ~ 19 parts, Bulbus Fritillariae Thunbergii 5 ~ 7 parts, Fel Serpentis 6 ~ 9 parts, Fractus Eriobotryae 6 ~ 9 parts, Radix Adenophorae (Radix Glehniae) 10 ~ 20 parts, Radix Ophiopogonis 10 ~ 18 parts, raw Rhizoma Polygonati Odorati 12 ~ 17 parts, Radix Trichosanthis 10 ~ 23 parts, 8 ~ 20 parts, Seem Lablab Album, 2 ~ 8 parts, Folium Mori, Pupa bombycis 6 ~ 12 parts, Herba Dendrobii 10 ~ 23 parts, Flos Farfarae 7 ~ 9 parts, Fructus Schisandrae Chinensis 8 ~ 12 parts, Fgopyrum dibotrys Hara 12 ~ 20 parts, the subcutaneous mucus of Cupressaceae 5 ~ 9 parts, Cacumen Cupressi 10 ~ 12 parts, Fructus Citri Sarcodactylis 7 ~ 9 parts, Radix Bupleuri 12 ~ 16 parts, 7 ~ 23 parts, fresh Folium Bambusae, Endothelium Corneum Gigeriae Galli 12 ~ 15 parts, Radix Angelicae Sinensis 8 ~ 15 parts, 5 ~ 7 parts, Poria, Cortex Magnoliae Officinalis 9 ~ 18 parts and Herba Eupatorii 10 ~ 18 parts.
3. the medicine for the treatment of nonsmall-cell lung cancer according to claim 1 postoperative stagnant heat resistance lung card, it is characterized in that: calculate by weight, comprise Rhizoma Phragmitis 60 parts, Semen Coicis 30 parts, Semen Benincasae 24 parts, 12 parts, Semen Persicae, Herba Houttuyniae 30 parts, Pumex 12 parts, Flos Lonicerae 20 parts, Fructus Forsythiae 18 parts, Flos Inulae 2 parts, 10 parts, Semen Armeniacae Amarum, cortex trichosanthis 20 parts, Radix Rubiae 8 parts, Cortex Moutan 6 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Aurantii 20 parts, Exocarpium Citri Rubrum 30 parts, loose 5 parts of Concha Meretricis Seu Cyclinae, Rhizoma Imperatae 9 parts, Radix Glycyrrhizae 10 parts, Bulbus Fritillariae Cirrhosae 6 parts, Fel Serpentis 7 parts, Fractus Eriobotryae 8 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Ophiopogonis 14 parts, raw Rhizoma Polygonati Odorati 14.5 parts, Radix Trichosanthis 18 parts, 17 parts, Seem Lablab Album, 6 parts, Folium Mori, Pupa bombycis 8 parts, Herba Dendrobii 17 parts, Flos Farfarae 8 parts, Fructus Schisandrae Chinensis 10 parts, Fgopyrum dibotrys Hara 17 parts, the subcutaneous mucus of Cupressaceae 6 parts, Cacumen Cupressi 11 parts, Fructus Citri Sarcodactylis 8 parts, Radix Bupleuri 14 parts, 17 parts, fresh Folium Bambusae, Endothelium Corneum Gigeriae Galli 13 parts, Radix Angelicae Sinensis 12 parts, 8 parts, Poria, Cortex Magnoliae Officinalis 12 parts and Herba Eupatorii 16 parts, add weijing decoction and decoct patent medicine soup.
4. according to the medicine of claim 1,2 or 3 arbitrary described treatment nonsmall-cell lung cancer postoperative stagnant heat resistance lung card, it is characterized in that: described weijing decoction is added water 100 parts by Rhizoma Phragmitis 30 ~ 60 parts, Semen Coicis 20 ~ 40 parts, 5 ~ 16 parts, Semen Persicae, Rhizoma Phragmitis 15 ~ 18 parts and Semen Benincasae 17 ~ 23 parts and decocts boiling through intense fire, and after boiling, add 20 parts of water continue slow fire boiling, heating is stopped, by stand-by for 100 parts of weijing decoction coolings of making after filtering medicinal residues after residue 100 parts of medicine soup bodies.
5. treat the preparation method of the medicine of nonsmall-cell lung cancer postoperative stagnant heat resistance lung card, it is characterized in that: the decoction comprising medicine.
6. the preparation method of the medicine for the treatment of nonsmall-cell lung cancer according to claim 5 postoperative stagnant heat resistance lung card, is characterized in that:
Described drug decocting step is as follows:
(1) Rhizoma Phragmitis 40 ~ 70 parts, Semen Coicis 20 ~ 55 parts, Semen Benincasae 16 ~ 32 parts, 10 ~ 15 parts, Semen Persicae, Herba Houttuyniae 15 ~ 40 parts, Pumex 10 ~ 16 parts, Flos Lonicerae 10 ~ 30 parts, Fructus Forsythiae 5 ~ 20 parts, Flos Inulae 0.5 ~ 5 part, 8 ~ 16 parts, Semen Armeniacae Amarum, cortex trichosanthis 10 ~ 15 parts, Radix Rubiae 3 ~ 12 parts, Cortex Moutan 4 ~ 8 parts, Radix Salviae Miltiorrhizae 9 ~ 19 parts, Fructus Aurantii 10 ~ 30 parts, Exocarpium Citri Rubrum 10 ~ 40 parts, loose 3 ~ 10 parts of Concha Meretricis Seu Cyclinae, Rhizoma Imperatae 7 ~ 12 parts, Radix Glycyrrhizae 5 ~ 19 parts, Bulbus Fritillariae Thunbergii 5 ~ 7 parts, Fel Serpentis 6 ~ 9 parts, Fractus Eriobotryae 6 ~ 9 parts, Radix Adenophorae (Radix Glehniae) 10 ~ 20 parts, Radix Ophiopogonis 10 ~ 18 parts, raw Rhizoma Polygonati Odorati 12 ~ 17 parts, Radix Trichosanthis 10 ~ 23 parts, 8 ~ 20 parts, Seem Lablab Album, 2 ~ 8 parts, Folium Mori, Pupa bombycis 6 ~ 12 parts, Herba Dendrobii 10 ~ 23 parts, Flos Farfarae 7 ~ 9 parts, Fructus Schisandrae Chinensis 8 ~ 12 parts, Fgopyrum dibotrys Hara 12 ~ 20 parts, the subcutaneous mucus of Cupressaceae 5 ~ 9 parts, Cacumen Cupressi 10 ~ 12 parts, Fructus Citri Sarcodactylis 7 ~ 9 parts, Radix Bupleuri 12 ~ 16 parts, 7 ~ 23 parts, fresh Folium Bambusae, Endothelium Corneum Gigeriae Galli 12 ~ 15 parts, Radix Angelicae Sinensis 8 ~ 15 parts, 5 ~ 7 parts, Poria, Cortex Magnoliae Officinalis 9 ~ 18 parts and Herba Eupatorii 10 ~ 18 parts are put into and decoct vessel, soak 15 ~ 2 minutes to decocting the mixed solution adding clear water and DBDMH in vessel,
Wherein: clear water is 100: 0.2 ~ 1 with DBDMH mixed weight ratio, then the water decocted in vessel is outwelled, again utilize aseptic clear water to rinse medicine 2 ~ 3 times, and the water of cleaning is outwelled;
(2) in decoction vessel, add weijing decoction 100 parts, spacious lid utilizes intense fire to decoct to latter 8 ~ 10 minutes of boiling; Right pot cover decocts, and changes intense fire into slow fire simultaneously, and makes intrinsic pressure the trying hard to keep of decoction vessel hold 66 ~ 72KPa, continues this pressure and decocts 3 ~ 5 minutes;
(3) in time decocting vessel inside residue 1L medicine soup, heating is stopped, pressure to be released, open wide pot cover, when medicine soup temperature is more than 80 DEG C, utilize steel spoon and strainer extruding medicine, medicine soup in medicine is all squeezed out, completes being separated of medicine soup and medicinal residues.
7. promote the using method of the medicine of nonsmall-cell lung cancer post-operative recovery, it is characterized in that: concrete steps are as follows:
(1), when medicine soup being cooled to 30 ~ 50 DEG C, a point morning and evening takes for twice, each 0.5L;
(2) then isolated medicinal residues are loaded gunnysack, and medicinal residues temperature at 43 ~ 60 DEG C time carry out pulmonary's external application, partner treatment for patient, external application is half an hour before and after medication, until after medication half an hour terminate.
8. the using method of the medicine for the treatment of nonsmall-cell lung cancer according to claim 7 postoperative stagnant heat resistance lung card, it is characterized in that: drug administration on time, the pulse frequency of patient medication after 3 days is 81-99 beat/min, respiratory frequency is 18-12 beat/min, cough and expectoration is 10-18ml/ day, and chest pain degree is II degree moderate pain, and after movable, pulse frequency is 92-115 beat/min, Hb numerical value is 110-128g/l, and leukocyte count is 8-13 × 10
9/ l.
9. the using method of the medicine for the treatment of nonsmall-cell lung cancer according to claim 7 postoperative stagnant heat resistance lung card, it is characterized in that: drug administration on time, the pulse frequency of patient medication after one week is 60-90 beat/min, respiratory frequency is 16 ~ 20 beats/min, cough and expectoration is nothing, chest pain degree be O degree not bitterly, after movable, pulse frequency is 60-100 beat/min, Hb numerical value is 120-140g/l, and leukocyte count is 4-10 × 10
9/ l.
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| CN116407600B (en) * | 2023-04-03 | 2024-05-17 | 浙江省立同德医院(浙江省精神卫生研究院) | Traditional Chinese medicine compound for treating lung cancer and application of traditional Chinese medicine compound for treating lung nodule |
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Application publication date: 20151209 |