CN104257774B - A kind of Chinese medicine preparation of blood pressure lowering - Google Patents
A kind of Chinese medicine preparation of blood pressure lowering Download PDFInfo
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- CN104257774B CN104257774B CN201410576341.3A CN201410576341A CN104257774B CN 104257774 B CN104257774 B CN 104257774B CN 201410576341 A CN201410576341 A CN 201410576341A CN 104257774 B CN104257774 B CN 104257774B
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- radix
- herba
- blood pressure
- crude drug
- chinese medicine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
Abstract
The invention discloses the Chinese medicine preparation of a kind of blood pressure lowering, be made up of the Chinese crude drug of following weight: Radix Liquidambaris 55g, Herba Alternantherae Versicoloris 10g, Herba thalictri sibirici 10g, Radix Canavaliae 10g, Herba Lamii Amplexicaulis 5g, Radix desmodiik microphylli 3g; Preparation method is: the Chinese crude drug of above-mentioned weight is first put into drug-decocting appliance, adds pure water 2000 milliliters; Soak half an hour, make Chinese crude drug be sufficiently humidified so as to, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead to decoct 1 hour, after being filtered to remove medicinal residues, obtain herb liquid; The heating of described herb liquid is concentrated into 1000 milliliters and get final product. The present invention is for the treatment of hypertension.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically refer to the Chinese medicine preparation of a kind of blood pressure lowering.
Background technology
Hypertension is a kind of to continue to raise the chronic disease into main manifestations with arteriotony, one of principal pathogenetic reason is due to human peripheral arteriolospasm, human peripheral small artery resistance is made to strengthen, thus causing blood pressure to increase, form hypertension, often cause the pathological changes of the vitals such as the heart, brain, kidney and corresponding consequence occurs. Long-term hypertension can cause cardiovascular disease such as myocardial infarction, coronary heart disease etc., it is also possible to causes renal arteriosclerosis, thus causing renal insufficiency, uremia etc.
At present, the treatment major part of hypertension is also dependent on western medicine, though Western medicine can meet general blood pressure lowering requirement, but also has obvious side effect. Owing to Western medicine blood pressure lowering is all to expand blood vessel, and blood vessel dies down at continuous process of expansion Elastic and hardens, hence in so that the people of life-time service depressor easily caused by sclerosis of blood vessels and is broken, and causes the disease such as cerebral vessels embolism, apoplexy. Therefore, Western medicine is not suitable for permanent use. Research is screened Chinese patent medicine evident in efficacy, that side effect is low and is seemed particularly necessary.
Summary of the invention
The object of the invention is contemplated to make up the defect of prior art, it is provided that a kind of instant effect, the blood pressure lowering that evident in efficacy, side effect is low, cost is low Chinese medicine preparation, particular by techniques below scheme realize:
The Chinese medicine preparation of a kind of blood pressure lowering, is made up of the Chinese crude drug of following weight: Radix Liquidambaris 35 ~ 75g, Herba Alternantherae Versicoloris 5 ~ 15g, Herba thalictri sibirici 5 ~ 15g, Radix Canavaliae 5 ~ 15g, Herba Lamii Amplexicaulis 2 ~ 8g, Radix desmodiik microphylli 1 ~ 5g.
Preferably, the Chinese medicine preparation of a kind of blood pressure lowering, it is made up of the Chinese crude drug of following weight: Radix Liquidambaris 55g, Herba Alternantherae Versicoloris 10g, Herba thalictri sibirici 10g, Radix Canavaliae 10g, Herba Lamii Amplexicaulis 5g, Radix desmodiik microphylli 3g.
The preparation method of the Chinese medicine preparation of above-mentioned blood pressure lowering is: the Chinese crude drug of above-mentioned weight is first put into drug-decocting appliance, adds pure water 2000 milliliters; Soak half an hour, make Chinese crude drug be sufficiently humidified so as to, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead to decoct 1 hour, after being filtered to remove medicinal residues, obtain herb liquid; The heating of described herb liquid is concentrated into 1000 milliliters, obtains the Chinese medicine preparation of blood pressure lowering.
Radix Liquidambaris: [source] is the root of Hamamelidaceae Plants Chinese sweet gum LiquidambarformosanaHance.[function cures mainly] removing toxic substances and promoting subsidence of swelling; Wind-expelling pain-stopping. Main carbuncle furuncle; Rheumatic arthralgia; Toothache; Diarrhea due to damp-heat; Dysentery; Infantile dyspepsia.
Herba Alternantherae Versicoloris: [source] is the herb of the red Alternanthera sessilis (L.) DC. of amaranthaceous plant. [function cures mainly] heat-clearing and toxic substances removing, cooling blood for hemostasis, removing food stagnancy removing blood stasis.
Herba thalictri sibirici: herb that [source] is hair breeding plant Herba thalictri sibirici or root and rhizome. [function cures mainly] heat-clearing and toxic substances removing. Control cough due to lung-heat, angina.
Radix Canavaliae: the root of [source] leguminous plant Semen Canavaliae. [function cures mainly] controls wind syndrome of head, rheumatism pain along the spinal column, hernia, chronic dysentery, amenorrhea, traumatic injury.
Herba Lamii Amplexicaulis: [source] is the herb of labiate Herba Lamii Amplexicaulis. [function cures mainly] promoting blood circulation to remove obstruction in the collateral; Removing toxic substances and promoting subsidence of swelling. Main traumatic injury; Bones and muscles pain; Numb limbs and tense tendons; Hemiplegia; Face is completed; Jaundice; Nasal sinusitis; Scrofula; Toxic swelling; Impetigo.
Radix desmodiik microphylli: [source] is leguminous plant Herba Desmodii Microphylli DesmodiummicrophylLum(Thunb.) root of DC.. [function cures mainly] clearing away heat-damp and promoting diuresis; Relieving cough and asthma; Subduing swelling and detoxicating. Main stranguria caused by urinary stone; Stomachache; Jaundice; Dysentery; Cough; Asthma; Infantile malnutrition; Venom; Ulcerative carbuncle scrofula; Dermatitis rhus; Hemorrhoid.
The instructions of taking of above-mentioned Chinese medicine preparation is: twice on the one, sooner or later respectively once, each takes 20 ~ 50ml, within 30 days, is a course for the treatment of.
The present invention is made up of Chinese medicine, has suppressing the hyperactive liver to relieve the wind syndrome, alleviates effect of periphery arteriolospasm, declining so that crossing the QI and blood contained, reaching the purpose of blood pressure lowering. There is good effect, instant effect and the advantage having no side effect in the Chinese medicine preparation of the blood pressure lowering of the present invention, and raw materials used medicine is all cheap and easy to get.
Detailed description of the invention:
Below in conjunction with embodiment and case, the present invention is further illustrated.
Embodiment 1:
Weigh Radix Liquidambaris 35g, Herba Alternantherae Versicoloris 15g, Herba thalictri sibirici 5g, Radix Canavaliae 15g, Herba Lamii Amplexicaulis 2g, Radix desmodiik microphylli 5g put into drug-decocting appliance, add pure water 2000 milliliters; Soak half an hour, make Chinese crude drug be sufficiently humidified so as to, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead to decoct 1 hour, after being filtered to remove medicinal residues, obtain herb liquid; The heating of described herb liquid is concentrated into 1000 milliliters, obtains the Chinese medicine preparation of blood pressure lowering.
Embodiment 2:
Weigh Radix Liquidambaris 75g, Herba Alternantherae Versicoloris 5g, Herba thalictri sibirici 15g, Radix Canavaliae 5g, Herba Lamii Amplexicaulis 8g, Radix desmodiik microphylli 1g put into drug-decocting appliance, add pure water 2000 milliliters; Soak half an hour, make Chinese crude drug be sufficiently humidified so as to, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead to decoct 1 hour, after being filtered to remove medicinal residues, obtain herb liquid; The heating of described herb liquid is concentrated into 1000 milliliters, obtains the Chinese medicine preparation of blood pressure lowering.
Embodiment 3:
Weigh Radix Liquidambaris 55g, Herba Alternantherae Versicoloris 10g, Herba thalictri sibirici 10g, Radix Canavaliae 10g, Herba Lamii Amplexicaulis 5g, Radix desmodiik microphylli 3g put into drug-decocting appliance, add pure water 2000 milliliters; Soak half an hour, make Chinese crude drug be sufficiently humidified so as to, fully fried in order to medicine juice; Use slow fire after boiling with high heat instead to decoct 1 hour, after being filtered to remove medicinal residues, obtain herb liquid; The heating of described herb liquid is concentrated into 1000 milliliters, obtains the Chinese medicine preparation of blood pressure lowering.
Clinical testing data:
For checking the therapeutic effect of the present invention, choose Taihu County 105, Anqing, Anhui Province example patients with hypertension, the range of age 38 ~ 66 years old, 50 years old mean age, wherein male 53 example, women 52 example.105 example patient's stochastic averagina are divided into three groups, respectively treatment group 1, treatment group 2 and treatment group 3, often organize 35 example patients. Diagnostic criteria: shrink pressure equal to or higher than 160mmHg(21.3kPa), diastolic pressure equals to or higher than 95mmHg(12.721.3kPa), both have 1 verified, can make a definite diagnosis.
Therapeutic Method:
Treatment group 1 adopts the Chinese medicine for lowering blood pressure preparation of the embodiment of the present invention 1 to treat, twice on the one, sooner or later respectively once, each takes 30ml; Treatment group 2 adopts the Chinese medicine for lowering blood pressure preparation of the embodiment of the present invention 2 to treat, twice on the one, sooner or later respectively once, each takes 30ml; Treatment group 3 adopts the Chinese medicine for lowering blood pressure preparation of the embodiment of the present invention 3 to treat, twice on the one, sooner or later respectively once, each takes 30ml; Treat 30 days continuously respectively for above three groups.
Criterion of therapeutical effect:
Effective: 1. diastolic pressure decline 10mmHg(1.3kPa) more than, and reach normal range; Though 2. diastolic pressure is not near normally, but the 20mmHg(2.7kPa that declined) or more than, must possess wherein 1;
Effective: 1. diastolic pressure declines not as good as 10mmHg(1.3kPa), but reach normal range; 2. diastolic pressure relatively treats the front 10～19mmHg(1.3～2.5kPa that declines), but not up to normal range; 3. the pressure front decline 30mmHg(4kPa of relatively treatment is shunk); Must possess wherein 1;
Invalid: not up to above standard.
Therapeutic effect:
Treatment group 1: effective 12 examples, accounts for 34.3%; Effective 20 examples, account for 57.1%; Invalid 3 examples; Total effective rate 91.4%;
Treatment group 2: effective 11 examples, accounts for 31.4%; Effective 19 examples, account for 54.3%; Invalid 5 examples; Total effective rate 85.7%;
Treatment group 3: effective 27 examples, accounts for 77.1%; Effective 8 examples, account for 22.9%; Invalid 0 example; Total effective rate 100%.
From above-mentioned therapeutic outcome it can be seen that the Chinese medicine preparation of three embodiments of the present invention is respectively provided with good blood pressure reduction effect, total effective rate reaches more than 85.7%, wherein, the obvious effective rate of the Chinese medicine preparation of embodiment 3 is the highest, has reached 77.1%, achieves beyond thought effect.
After treatment, to all of the above 105, example patient carries out Effect of follow-up visit by telephone, continues half a year, does not find that the case such as cerebral vessels embolism, apoplexy occurs in an example, and hypertension relapse rate is less than 5%.
Claims (1)
1. the Chinese medicine preparation of a blood pressure lowering, it is characterised in that: it is made up of the Chinese crude drug of following weight: Radix Liquidambaris 55g, Herba Alternantherae Versicoloris 10g, Herba thalictri sibirici 10g, Radix Canavaliae 10g, Herba Lamii Amplexicaulis 5g, Radix desmodiik microphylli 3g; Preparation method is: the Chinese crude drug of above-mentioned weight is first put into drug-decocting appliance, adds pure water 2000 milliliters; Soak half an hour, make Chinese crude drug be sufficiently humidified so as to, be beneficial to medicine juice fully fried; Use slow fire after boiling with high heat instead to decoct 1 hour, after being filtered to remove medicinal residues, obtain herb liquid; The heating of described herb liquid is concentrated into 1000 milliliters, obtains the Chinese medicine preparation of blood pressure lowering.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410576341.3A CN104257774B (en) | 2014-10-26 | 2014-10-26 | A kind of Chinese medicine preparation of blood pressure lowering |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410576341.3A CN104257774B (en) | 2014-10-26 | 2014-10-26 | A kind of Chinese medicine preparation of blood pressure lowering |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104257774A CN104257774A (en) | 2015-01-07 |
| CN104257774B true CN104257774B (en) | 2016-06-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410576341.3A Expired - Fee Related CN104257774B (en) | 2014-10-26 | 2014-10-26 | A kind of Chinese medicine preparation of blood pressure lowering |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104840605A (en) * | 2015-05-26 | 2015-08-19 | 合肥丰瑞隆生物科技有限公司 | Antihypertensive traditional Chinese medicine |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103083557A (en) * | 2012-09-12 | 2013-05-08 | 刘炜 | Traditional Chinese medicine composition with functions of reducing blood pressure and blood fat |
| CN103446456B (en) * | 2013-01-01 | 2016-03-09 | 江西银涛药业有限公司 | Treatment hypertension and the method for hyperlipidaemic conditions and the Chinese medicine composition of use |
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| CN104257774A (en) | 2015-01-07 |
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| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhang Xiao Inventor after: Cao Fukai Inventor after: Li Yue Inventor after: Fu Xiao Inventor after: Zhao Liangjun Inventor before: Tong Wanjin |
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| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160510 Address after: 063000 Hebei province Tangshan City Xinhua West Road No. 46 North China University of science and technology Applicant after: North China Polytechnics Address before: Double Dunzhen Changfeng County of Hefei City, Anhui province 231131 miles community two building 602 room 2 Applicant before: Tong Wanjin |
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Granted publication date: 20160615 Termination date: 20171026 |
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| CF01 | Termination of patent right due to non-payment of annual fee |