CN104254903B - 具有快速响应的电子轰击离子源 - Google Patents

具有快速响应的电子轰击离子源 Download PDF

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Publication number
CN104254903B
CN104254903B CN201380021654.6A CN201380021654A CN104254903B CN 104254903 B CN104254903 B CN 104254903B CN 201380021654 A CN201380021654 A CN 201380021654A CN 104254903 B CN104254903 B CN 104254903B
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CN
China
Prior art keywords
source
ion source
electron bombardment
chromatography
mass spectrometer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201380021654.6A
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English (en)
Chinese (zh)
Other versions
CN104254903A (zh
Inventor
A·N·维尔恩驰寇韦
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Leco Corp
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Leco Corp
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Publication date
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Publication of CN104254903A publication Critical patent/CN104254903A/zh
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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/14—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers
    • H01J49/147—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers with electrons, e.g. electron impact ionisation, electron attachment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7206—Mass spectrometers interfaced to gas chromatograph
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0468—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
CN201380021654.6A 2012-04-26 2013-04-26 具有快速响应的电子轰击离子源 Expired - Fee Related CN104254903B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261638722P 2012-04-26 2012-04-26
US61/638,722 2012-04-26
PCT/US2013/038388 WO2013163530A2 (en) 2012-04-26 2013-04-26 Electron impact ion source with fast response

Publications (2)

Publication Number Publication Date
CN104254903A CN104254903A (zh) 2014-12-31
CN104254903B true CN104254903B (zh) 2017-05-24

Family

ID=48576502

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380021654.6A Expired - Fee Related CN104254903B (zh) 2012-04-26 2013-04-26 具有快速响应的电子轰击离子源

Country Status (5)

Country Link
US (1) US9123521B2 (enExample)
JP (2) JP2015515733A (enExample)
CN (1) CN104254903B (enExample)
DE (1) DE112013002194B4 (enExample)
WO (1) WO2013163530A2 (enExample)

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WO2015153644A1 (en) * 2014-03-31 2015-10-08 Leco Corporation Gc-tof ms with improved detection limit
CN104103488B (zh) * 2014-05-28 2016-06-15 北京大学 用于飞行时间质谱计的场发射电离源
JP6323362B2 (ja) * 2015-02-23 2018-05-16 株式会社島津製作所 イオン化装置
US10408951B2 (en) 2016-01-29 2019-09-10 Board Of Trustees Of Michigan State University Radiation detector
DE102016110495B4 (de) * 2016-06-07 2018-03-29 Vacom Vakuum Komponenten & Messtechnik Gmbh Vorrichtung und Verfahren zum Erzeugen, Speichern und Freisetzen von Ionen aus einer umgebenden Restgasatmosphäre
US10541122B2 (en) * 2017-06-13 2020-01-21 Mks Instruments, Inc. Robust ion source
WO2019030477A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov ACCELERATOR FOR MASS SPECTROMETERS WITH MULTIPASSES
US11239067B2 (en) 2017-08-06 2022-02-01 Micromass Uk Limited Ion mirror for multi-reflecting mass spectrometers
GB201806507D0 (en) * 2018-04-20 2018-06-06 Verenchikov Anatoly Gridless ion mirrors with smooth fields
GB201807626D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
WO2019217541A1 (en) 2018-05-11 2019-11-14 Leco Corporation Two-stage ion source comprising closed and open ion volumes
GB201808530D0 (en) 2018-05-24 2018-07-11 Verenchikov Anatoly TOF MS detection system with improved dynamic range
GB201810573D0 (en) 2018-06-28 2018-08-15 Verenchikov Anatoly Multi-pass mass spectrometer with improved duty cycle
US11056330B2 (en) 2018-12-21 2021-07-06 Thermo Finnigan Llc Apparatus and system for active heat transfer management in ESI ion sources
GB201903779D0 (en) 2019-03-20 2019-05-01 Micromass Ltd Multiplexed time of flight mass spectrometer
CN112599397B (zh) * 2020-12-14 2023-06-06 兰州空间技术物理研究所 一种储存式离子源
US11768176B2 (en) 2022-01-06 2023-09-26 Mks Instruments, Inc. Ion source with gas delivery for high-fidelity analysis
KR102587356B1 (ko) * 2022-12-12 2023-10-12 주식회사 아스타 차동 진공 이온화 원

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US4039828A (en) * 1973-12-13 1977-08-02 Uranit Uran-Isotopentrennungs-Gmbh Quadrupole mass spectrometer
JP2004247162A (ja) * 2003-02-13 2004-09-02 Toyota Motor Corp 高真空分析装置
JP2005259482A (ja) * 2004-03-11 2005-09-22 Shimadzu Corp イオン化装置
JP2010244903A (ja) * 2009-04-07 2010-10-28 Shimadzu Corp 質量分析装置
WO2011107836A1 (en) * 2010-03-02 2011-09-09 Anatoly Verenchikov Open trap mass spectrometer
WO2012024468A2 (en) * 2010-08-19 2012-02-23 Leco Corporation Time-of-flight mass spectrometer with accumulating electron impact ion source

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JPH03201355A (ja) * 1989-12-27 1991-09-03 Jeol Ltd 大気圧イオン化質量分析装置
US5055678A (en) * 1990-03-02 1991-10-08 Finnigan Corporation Metal surfaces for sample analyzing and ionizing apparatus
JP2777327B2 (ja) * 1994-02-02 1998-07-16 株式会社東京カソード研究所 質量分析用ガス導入バルブ
JPH08254504A (ja) * 1994-11-29 1996-10-01 Zellweger Luwa Ag 伸長された物体の特性を記録するための方法と装置
US5847385A (en) * 1996-08-09 1998-12-08 Analytica Of Branford, Inc. Mass resolution by angular alignment of the ion detector conversion surface in time-of-flight mass spectrometers with electrostatic steering deflectors
WO2000077823A2 (en) * 1999-06-11 2000-12-21 Perseptive Biosystems, Inc. Tandem time-of-flight mass spectometer with damping in collision cell and method for use
JP5357538B2 (ja) * 2005-03-22 2013-12-04 レコ コーポレイション 等時性湾曲イオンインタフェースを備えた多重反射型飛行時間質量分析計
USRE44147E1 (en) * 2006-03-09 2013-04-16 Shimadzu Corporation Mass spectrometer
EP1855306B1 (en) * 2006-05-11 2019-11-13 ISB - Ion Source & Biotechnologies S.R.L. Ionization source and method for mass spectrometry
US7709789B2 (en) * 2008-05-29 2010-05-04 Virgin Instruments Corporation TOF mass spectrometry with correction for trajectory error
DE112008003955B4 (de) * 2008-07-28 2018-02-08 Leco Corp. Ionenführung, Verwendung einer solchen Ionenführung, Schnittstelle, gepulster Ionenkonverter für die Ionenführung sowie Verfahren zur Ionenmanipulation
US20100301202A1 (en) 2009-05-29 2010-12-02 Virgin Instruments Corporation Tandem TOF Mass Spectrometer With High Resolution Precursor Selection And Multiplexed MS-MS
WO2011055521A1 (ja) * 2009-11-06 2011-05-12 株式会社日立ハイテクノロジーズ 荷電粒子顕微鏡
US8299421B2 (en) * 2010-04-05 2012-10-30 Agilent Technologies, Inc. Low-pressure electron ionization and chemical ionization for mass spectrometry
WO2011127091A1 (en) * 2010-04-05 2011-10-13 Indiana University Research And Technology Corporation Method for enhancement of mass resolution over a limited mass range for time-of-flight spectrometry
GB201007210D0 (en) * 2010-04-30 2010-06-16 Verenchikov Anatoly Time-of-flight mass spectrometer with improved duty cycle
GB201022050D0 (en) * 2010-12-29 2011-02-02 Verenchikov Anatoly Electrostatic trap mass spectrometer with improved ion injection

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039828A (en) * 1973-12-13 1977-08-02 Uranit Uran-Isotopentrennungs-Gmbh Quadrupole mass spectrometer
JP2004247162A (ja) * 2003-02-13 2004-09-02 Toyota Motor Corp 高真空分析装置
JP2005259482A (ja) * 2004-03-11 2005-09-22 Shimadzu Corp イオン化装置
JP2010244903A (ja) * 2009-04-07 2010-10-28 Shimadzu Corp 質量分析装置
WO2011107836A1 (en) * 2010-03-02 2011-09-09 Anatoly Verenchikov Open trap mass spectrometer
WO2012024468A2 (en) * 2010-08-19 2012-02-23 Leco Corporation Time-of-flight mass spectrometer with accumulating electron impact ion source

Also Published As

Publication number Publication date
JP2017098267A (ja) 2017-06-01
DE112013002194T5 (de) 2015-01-08
WO2013163530A2 (en) 2013-10-31
JP6383023B2 (ja) 2018-08-29
CN104254903A (zh) 2014-12-31
DE112013002194B4 (de) 2020-12-24
US9123521B2 (en) 2015-09-01
US20150144779A1 (en) 2015-05-28
JP2015515733A (ja) 2015-05-28
WO2013163530A3 (en) 2014-08-14

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