CN104246501B - 生物化验样品分析器 - Google Patents

生物化验样品分析器 Download PDF

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Publication number
CN104246501B
CN104246501B CN201380021187.7A CN201380021187A CN104246501B CN 104246501 B CN104246501 B CN 104246501B CN 201380021187 A CN201380021187 A CN 201380021187A CN 104246501 B CN104246501 B CN 104246501B
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CN
China
Prior art keywords
sample
test
reflector
shuttle
detector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201380021187.7A
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English (en)
Chinese (zh)
Other versions
CN104246501A (zh
Inventor
J.R.贾斯珀斯
N.P.德斯马赖斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Inc
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Siemens Healthcare Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Healthcare Diagnostics Inc filed Critical Siemens Healthcare Diagnostics Inc
Publication of CN104246501A publication Critical patent/CN104246501A/zh
Application granted granted Critical
Publication of CN104246501B publication Critical patent/CN104246501B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6471Special filters, filter wheel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6473In-line geometry
    • G01N2021/6476Front end, i.e. backscatter, geometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/02Mechanical
    • G01N2201/024Modular construction
    • G01N2201/0245Modular construction with insertable-removable part
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/063Illuminating optical parts
    • G01N2201/0634Diffuse illumination
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/063Illuminating optical parts
    • G01N2201/0636Reflectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/066Modifiable path; multiple paths in one sample
    • G01N2201/0666Selectable paths; insertable multiple sources

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN201380021187.7A 2012-04-23 2013-04-23 生物化验样品分析器 Expired - Fee Related CN104246501B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261636860P 2012-04-23 2012-04-23
US61/636860 2012-04-23
PCT/US2013/037712 WO2013163129A1 (en) 2012-04-23 2013-04-23 Biological assay sample analyzer

Publications (2)

Publication Number Publication Date
CN104246501A CN104246501A (zh) 2014-12-24
CN104246501B true CN104246501B (zh) 2016-06-29

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380021187.7A Expired - Fee Related CN104246501B (zh) 2012-04-23 2013-04-23 生物化验样品分析器

Country Status (10)

Country Link
US (1) US9606067B2 (enExample)
EP (2) EP2841926B1 (enExample)
JP (1) JP5797870B2 (enExample)
KR (1) KR101530168B1 (enExample)
CN (1) CN104246501B (enExample)
BR (1) BR112014026197B1 (enExample)
CA (1) CA2871658C (enExample)
IN (1) IN2014DN08156A (enExample)
MX (1) MX336583B (enExample)
WO (1) WO2013163129A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016034775A1 (en) 2014-09-05 2016-03-10 Thermo Fisher Scientific Oy Method and apparatus for optical measurement of liquid sample
KR102567775B1 (ko) * 2015-03-13 2023-08-16 쓰리엠 이노베이티브 프로퍼티즈 컴파니 광 검출 시스템 및 그의 사용 방법
EP3413051B1 (de) * 2017-06-09 2020-07-29 Siemens Healthcare Diagnostics Products GmbH Aktivierungstest zur diagnose einer heparin-induzierten thrombozytopenie
EP3685131B1 (en) * 2017-09-19 2022-09-07 Beckman Coulter, Inc. Analog light measuring and photon counting in chemiluminescence measurements
CN116802480A (zh) * 2021-02-03 2023-09-22 美国西门子医学诊断股份有限公司 高灵敏度化学发光检测系统和方法
KR102600532B1 (ko) 2021-04-07 2023-11-08 중앙대학교 산학협력단 화학발광 측정장치
CN117795318A (zh) * 2021-08-02 2024-03-29 3M创新有限公司 光学系统、光学构造体、光学循环多孔板和光学检测系统
USD1069156S1 (en) 2023-04-10 2025-04-01 Becton, Dickinson And Company Dispensing device

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562356A (en) * 1983-11-28 1985-12-31 Midac Corporation Apparatus and method for photoluminescence analysis
US4795256A (en) * 1987-03-09 1989-01-03 Photon Technology International, Inc. Dual-wavelength spectrophotometry system
US5575977A (en) * 1990-04-23 1996-11-19 Solid State Farms, Inc. Apparatus for sedimentation based blood analysis
CN1302377A (zh) * 1998-03-23 2001-07-04 阿斯特拉曾尼卡有限公司 分析样品中组分的三维分布的方法和设备
CN1549921A (zh) * 2001-06-29 2004-11-24 ÷ 发光测试检测用的检测板、读数系统和方法
US6867851B2 (en) * 1999-11-04 2005-03-15 Regents Of The University Of Minnesota Scanning of biological samples
CN1717579A (zh) * 2002-11-27 2006-01-04 3M创新有限公司 生物培养板扫描装置
WO2007133465A2 (en) * 2006-05-12 2007-11-22 Immunivest Corporation A laser illumination system in fluorescent microscopy
CN101189505A (zh) * 2005-04-01 2008-05-28 3M创新有限公司 具有可移除光学模块的多重荧光检测装置
CN101622522A (zh) * 2007-01-26 2010-01-06 贝克顿·迪金森公司 用于细胞计数和分析的方法、系统和组合物

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS535955B2 (enExample) * 1972-12-26 1978-03-03
US4153369A (en) 1977-11-11 1979-05-08 Farrand Optical Co., Inc. Convertible dual beam differential spectrofluorometer and absorption meter
DE3204686A1 (de) * 1982-02-11 1983-08-18 Fa. Carl Zeiss, 7920 Heidenheim Optisches system zur durchlichtmikroskopie bei auflichtbeleuchtung
JP3464798B2 (ja) 1992-07-31 2003-11-10 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 光活性化化学発光基質
AU715627B2 (en) 1996-02-21 2000-02-03 Biomerieux Vitek, Inc. Automatic sample testing machine
DE19942998B4 (de) * 1999-09-09 2012-02-09 Carl Zeiss Jena Gmbh Mikroskop zur Auf- und Durchlichtmikroskopie
US6725294B1 (en) * 2001-02-20 2004-04-20 Lsi Logic Corporation Installation and access of a device handler for a peripheral device in a computer
JP2002277396A (ja) * 2001-03-19 2002-09-25 Minolta Co Ltd 発光検出装置
US6750457B2 (en) * 2001-08-29 2004-06-15 Becton Dickinson And Company System for high throughput analysis
JP2003207453A (ja) 2002-01-16 2003-07-25 Hitachi High-Technologies Corp 蛍光,燐光測定装置
US6970240B2 (en) * 2003-03-10 2005-11-29 Applera Corporation Combination reader
US7402281B2 (en) 2003-07-18 2008-07-22 Siemens Healthcare Diagnostics Inc. Magazine for inventorying reaction cuvettes in an automatic analyzer
US20060195058A1 (en) * 2005-02-14 2006-08-31 Gable Jennifer H Methods and apparatus for extracting and analyzing a bodily fluid
US7507575B2 (en) 2005-04-01 2009-03-24 3M Innovative Properties Company Multiplex fluorescence detection device having removable optical modules
WO2007004708A1 (ja) * 2005-06-30 2007-01-11 National University Corporation NARA Institute of Science and Technology 顕微鏡
US7702139B2 (en) * 2006-10-13 2010-04-20 Carestream Health, Inc. Apparatus for caries detection
WO2008072597A1 (ja) * 2006-12-12 2008-06-19 Nikon Corporation 顕微鏡装置及び画像処理方法
WO2009056669A1 (en) * 2007-10-31 2009-05-07 Wallac Oy Sample measurement system
JP5300249B2 (ja) 2007-11-21 2013-09-25 株式会社日立ハイテクノロジーズ 液体分析装置
JP5087386B2 (ja) * 2007-12-18 2012-12-05 オリンパス株式会社 顕微鏡
EP2315065B1 (en) * 2009-10-26 2015-05-13 Olympus Corporation Microscope

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562356A (en) * 1983-11-28 1985-12-31 Midac Corporation Apparatus and method for photoluminescence analysis
US4795256A (en) * 1987-03-09 1989-01-03 Photon Technology International, Inc. Dual-wavelength spectrophotometry system
US5575977A (en) * 1990-04-23 1996-11-19 Solid State Farms, Inc. Apparatus for sedimentation based blood analysis
CN1302377A (zh) * 1998-03-23 2001-07-04 阿斯特拉曾尼卡有限公司 分析样品中组分的三维分布的方法和设备
US6867851B2 (en) * 1999-11-04 2005-03-15 Regents Of The University Of Minnesota Scanning of biological samples
CN1549921A (zh) * 2001-06-29 2004-11-24 ÷ 发光测试检测用的检测板、读数系统和方法
CN1717579A (zh) * 2002-11-27 2006-01-04 3M创新有限公司 生物培养板扫描装置
CN101189505A (zh) * 2005-04-01 2008-05-28 3M创新有限公司 具有可移除光学模块的多重荧光检测装置
WO2007133465A2 (en) * 2006-05-12 2007-11-22 Immunivest Corporation A laser illumination system in fluorescent microscopy
CN101622522A (zh) * 2007-01-26 2010-01-06 贝克顿·迪金森公司 用于细胞计数和分析的方法、系统和组合物

Also Published As

Publication number Publication date
MX2014012772A (es) 2014-11-21
US9606067B2 (en) 2017-03-28
JP2015515009A (ja) 2015-05-21
EP2841926A4 (en) 2015-11-18
US20150118690A1 (en) 2015-04-30
KR101530168B1 (ko) 2015-06-19
EP3324175A1 (en) 2018-05-23
WO2013163129A1 (en) 2013-10-31
BR112014026197A2 (pt) 2017-06-27
MX336583B (es) 2016-01-21
EP2841926A1 (en) 2015-03-04
IN2014DN08156A (enExample) 2015-05-01
KR20140146665A (ko) 2014-12-26
EP3324175B1 (en) 2023-07-19
CA2871658C (en) 2015-09-15
CA2871658A1 (en) 2013-10-31
JP5797870B2 (ja) 2015-10-21
BR112014026197B1 (pt) 2020-10-13
CN104246501A (zh) 2014-12-24
EP2841926B1 (en) 2017-07-26

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Granted publication date: 20160629