CN104244971B - 抗疟疾微颗粒疫苗 - Google Patents

抗疟疾微颗粒疫苗 Download PDF

Info

Publication number
CN104244971B
CN104244971B CN201380018173.XA CN201380018173A CN104244971B CN 104244971 B CN104244971 B CN 104244971B CN 201380018173 A CN201380018173 A CN 201380018173A CN 104244971 B CN104244971 B CN 104244971B
Authority
CN
China
Prior art keywords
polyelectrolyte
epitope
composition
polypeptide
antigenic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201380018173.XA
Other languages
English (en)
Chinese (zh)
Other versions
CN104244971A (zh
Inventor
托马斯·J·鲍威尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Artificial Cell Technologies Inc
Original Assignee
Artificial Cell Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Artificial Cell Technologies Inc filed Critical Artificial Cell Technologies Inc
Publication of CN104244971A publication Critical patent/CN104244971A/zh
Application granted granted Critical
Publication of CN104244971B publication Critical patent/CN104244971B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201380018173.XA 2012-03-30 2013-03-20 抗疟疾微颗粒疫苗 Active CN104244971B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261617998P 2012-03-30 2012-03-30
US61/617,998 2012-03-30
PCT/US2013/033070 WO2013148426A1 (en) 2012-03-30 2013-03-20 Microparticle vaccine against malaria

Publications (2)

Publication Number Publication Date
CN104244971A CN104244971A (zh) 2014-12-24
CN104244971B true CN104244971B (zh) 2016-09-07

Family

ID=48050943

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380018173.XA Active CN104244971B (zh) 2012-03-30 2013-03-20 抗疟疾微颗粒疫苗

Country Status (12)

Country Link
US (1) US9433671B2 (enExample)
EP (1) EP2830653B1 (enExample)
JP (1) JP6335876B2 (enExample)
CN (1) CN104244971B (enExample)
AU (1) AU2013240105B2 (enExample)
BR (1) BR112014024374B1 (enExample)
CA (1) CA2868450C (enExample)
DK (1) DK2830653T3 (enExample)
ES (1) ES2885806T3 (enExample)
IL (1) IL234694B (enExample)
MX (1) MX350709B (enExample)
WO (1) WO2013148426A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012018628A1 (en) 2010-07-26 2012-02-09 Board Of Regents, The University Of Texas System Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine
US8883717B2 (en) 2012-03-30 2014-11-11 Artificial Cell Technologies, Inc. Antigenic compositions and methods
US9974850B2 (en) 2013-01-25 2018-05-22 Board Of Regents, The University Of Texas System Immunogenic compositions and uses thereof
JP6934862B2 (ja) * 2015-09-16 2021-09-15 アーティフィシャル セル テクノロジーズ インコーポレイテッド 抗マラリア組成物および方法
WO2017075053A1 (en) * 2015-10-26 2017-05-04 Cour Pharmaceuticals Development Company Inc. Immune-modifying particles for the treatment of malaria
AU2019355843A1 (en) * 2018-10-04 2021-03-04 Artificial Cell Technologies, Inc. Anti-malaria compositions and methods
WO2024063789A1 (en) * 2022-09-23 2024-03-28 BioNTech SE Compositions for delivery of malaria antigens and related methods
JP2025533527A (ja) * 2022-09-23 2025-10-07 ビオンテック・ソシエタス・エウロパエア Ｐｌａｓｍｏｄｉｕｍ ＣＳＰ抗原の送達のための組成物及び関連方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009082440A2 (en) * 2007-12-18 2009-07-02 Vaxinnate Corporation Compositions of toll-like receptor agonists and malaria antigens and methods of use

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2150493T5 (es) 1993-05-25 2004-07-01 Wyeth Holdings Corporation Adyuvantes para vacunas contra el virus sincitico respiratorio.
US7101575B2 (en) 1998-03-19 2006-09-05 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
DE10001172A1 (de) 2000-01-13 2001-07-26 Max Planck Gesellschaft Templatieren von Feststoffpartikeln mit Polymermultischichten
WO2004108072A2 (en) 2003-04-10 2004-12-16 3M Innovative Properties Company Delivery of immune response modifier compounds using metal-containing particulate support materials
US7348399B2 (en) 2003-08-29 2008-03-25 Louisiana Tech University Foundation, Inc. Nanofabricated polypeptide multilayer films, coatings, and microcapsules
US7615530B2 (en) 2003-08-29 2009-11-10 Artificial Cell Technologies, Inc. Immunogenic compositions and methods of use
DE102004013637A1 (de) 2004-03-19 2005-10-13 Capsulution Nanoscience Ag Verfahren zur Herstellung von CS-Partikeln und Mikrokapseln unter Verwendung poröser Template sowie CS-Partikel und Mikrokapseln
CN101151020B (zh) 2005-02-07 2011-09-07 利波特卡有限公司 佐剂材料
DE102005044400A1 (de) 2005-09-16 2007-03-22 Capsulution Nanoscience Ag Verfahren zur Verkapselung und kontrollierten Freisetzung von schwer wasserlöslichen (hydrophoben) flüssigen und festen Wirkstoffen
AU2006347951B2 (en) 2005-10-25 2011-12-22 Louisiana Tech University Research Foundation Multilayer films, coatings and microcapsules comprising polypeptides
US8951528B2 (en) 2006-02-22 2015-02-10 3M Innovative Properties Company Immune response modifier conjugates
US20080149123A1 (en) 2006-12-22 2008-06-26 Mckay William D Particulate material dispensing hairbrush with combination bristles
US7723294B2 (en) 2007-04-02 2010-05-25 Artificial Cell Technologies, Inc. Polypeptide films and methods
EP2002847A1 (en) 2007-06-12 2008-12-17 Capsulution Nanoscience AG Drug-releasing polyelectrolyte coating, method for forming a drug-releasing polyelectrolyte coating, and implantable device
US7846824B2 (en) 2008-03-18 2010-12-07 Applied Materials, Inc. Methods for forming a titanium nitride layer
WO2010115229A1 (en) * 2009-04-09 2010-10-14 The University Of Melbourne Immunogenic composition and uses thereof
AU2011276251B2 (en) 2010-07-07 2015-02-05 Artifical Cell Technologies, Inc. Respiratory syncytial virus antigenic compositions and methods
US8883717B2 (en) 2012-03-30 2014-11-11 Artificial Cell Technologies, Inc. Antigenic compositions and methods

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009082440A2 (en) * 2007-12-18 2009-07-02 Vaxinnate Corporation Compositions of toll-like receptor agonists and malaria antigens and methods of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Synthetic nanoparticle vaccines produced by layer-by-layer assembly of artificial biofilms induce potent protective T-cell and antibody responses invivo;Thomas J.Powell et al;《Vaccine》;20101015;第29卷(第3期);第558-569页，参见摘要，图1，第1节和第2节 *

Also Published As

Publication number Publication date
CA2868450C (en) 2021-02-23
AU2013240105B2 (en) 2016-10-20
JP2015514087A (ja) 2015-05-18
IL234694B (en) 2021-09-30
MX350709B (es) 2017-09-14
HK1206972A1 (en) 2016-01-22
EP2830653B1 (en) 2021-08-11
JP6335876B2 (ja) 2018-05-30
CA2868450A1 (en) 2013-10-03
WO2013148426A1 (en) 2013-10-03
DK2830653T3 (da) 2021-09-13
CN104244971A (zh) 2014-12-24
BR112014024374B1 (pt) 2022-10-18
ES2885806T3 (es) 2021-12-15
IL234694A0 (en) 2014-11-30
BR112014024374A2 (enExample) 2017-06-20
US9433671B2 (en) 2016-09-06
US20130259945A1 (en) 2013-10-03
EP2830653A1 (en) 2015-02-04
MX2014011713A (es) 2015-02-04
AU2013240105A1 (en) 2014-10-02

Similar Documents

Publication Publication Date Title
CN104244971B (zh) 抗疟疾微颗粒疫苗
CN103037898B (zh) 呼吸道合胞病毒抗原组合物和方法
US9925252B2 (en) Antigenic compositions and methods
US10588954B2 (en) Anti-malaria compositions and methods
US20220096617A1 (en) Anti-malaria compositions and methods
HK1206972B (en) Microparticle/nanoparticle vaccine against malaria
HK1254028B (zh) 抗疟疾组合物和方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant