CN104225038A - Traditional Chinese medicine for treating acute orchitis - Google Patents

Traditional Chinese medicine for treating acute orchitis Download PDF

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Publication number
CN104225038A
CN104225038A CN201410530217.3A CN201410530217A CN104225038A CN 104225038 A CN104225038 A CN 104225038A CN 201410530217 A CN201410530217 A CN 201410530217A CN 104225038 A CN104225038 A CN 104225038A
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CN
China
Prior art keywords
radix
traditional chinese
chinese medicine
orchitis
treating acute
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Pending
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CN201410530217.3A
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Chinese (zh)
Inventor
洪英杰
杨雪芹
许丹
董宇翔
李有田
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First Hospital Jinlin University
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First Hospital Jinlin University
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Priority to CN201410530217.3A priority Critical patent/CN104225038A/en
Publication of CN104225038A publication Critical patent/CN104225038A/en
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Abstract

A traditional Chinese medicine for treating acute orchitis belongs to the field of traditional Chinese medicines. The invention aims to provide a traditional Chinese medicine for treating acute orchitis, which adopts the theory of traditional Chinese medicine and has the functions of clearing away heat and toxic material, promoting diuresis and reducing edema, promoting blood circulation and removing blood stasis, and dredging collaterals and relieving pain. The invention comprises the following raw materials in important parts: fructus Gardeniae, radix Isatidis, folium Isatidis, semen Citri Reticulatae, semen litchi, radix Gentianae, rhizoma corydalis, radix Et rhizoma Rhei, fructus Lipuidambaris, radix Angelicae sinensis, and radix Paeoniae Rubra. The invention has the advantages of simple preparation, low price, good curative effect, no toxic or side effect, short treatment time and good social and economic benefits. The invention is mainly used for treating acute orchitis or acute epididymitis and the like.

Description

A kind of Chinese medicine for the treatment of acute orchitis
Technical field
The invention belongs to tcm field.
Background technology
Acute testicular morbidity is anxious, state of an illness weight, and patient suffering is unbearable, if treatment is not in time or improper, then easily change acute epididymitis into, circuitous prolonging is not healed, and easily recurs, and can cause sexual hypofunction, spermatogenesis impairment, thus the one of the main reasons causing male sterility.
Doctor trained in Western medicine is to the treatment of acute orchitis, and mainly apply all kinds of antibiotic, although there is certain curative effect, its bad reaction is more, if drug allergy, or gastrointestinal side effect, the more important thing is the shortcomings such as this sick easily recurrence.
Summary of the invention
The object of the invention is to adopt theory of Chinese medical science, with heat-clearing and toxic substances removing, inducing diuresis and reducing edema, blood circulation promoting and blood stasis dispelling, the Chinese medicine of the treatment acute orchitis of removing obstruction in the collateral to relieve pain.
Important part of raw material that the present invention makes effective ingredient consists of:
Fructus Gardeniae 10-15 Radix Isatidis 15-25 Folium Isatidis 15-25
Semen Citri Reticulatae 15-20 Semen Litchi 15-20 Radix Gentianae 10-20
Rhizoma Corydalis 10-15 Radix Et Rhizoma Rhei 5-10 Fructus Liquidambaris 10-15
Radix Angelicae Sinensis 5-10 Radix Paeoniae Rubra 10-15.
The present invention prepares simply, cheap, and good effect, has no side effect, and treatment time is short, social and good in economic efficiency.The present invention is mainly used in treating acute orchitis or acute epididymitis etc.
Detailed description of the invention
Important part of raw material that the present invention makes effective ingredient consists of:
Fructus Gardeniae 10-15 Radix Isatidis 15-25 Folium Isatidis 15-25
Semen Citri Reticulatae 15-20 Semen Litchi 15-20 Radix Gentianae 10-20
Rhizoma Corydalis 10-15 Radix Et Rhizoma Rhei 5-10 Fructus Liquidambaris 10-15
Radix Angelicae Sinensis 5-10 Radix Paeoniae Rubra 10-15.
its preparation method is:
By above 11 taste Chinese medicines, add 8 times amount water soaking 30 minutes, decoct secondary, each 0.5 hour, filter, at merging filtrate, be concentrated into about 1000ml, add sodium benzoate 2g, make it dissolve, then cold preservation 12 hours, filter, filtrate adding distil water is adjusted to 1000ml, stirs evenly, subpackage and get final product.
embodiment 1
Important part of raw material that the present invention makes effective ingredient consists of:
Fructus Gardeniae 10, Radix Isatidis 15, Folium Isatidis 15, Semen Citri Reticulatae 15, Semen Litchi 15, Radix Gentianae 10, Rhizoma Corydalis 10, Radix Et Rhizoma Rhei 5, Fructus Liquidambaris 10, Radix Angelicae Sinensis 5, Radix Paeoniae Rubra 10
By above 11 taste Chinese medicines, add 8 times amount water enchroachment (invasion)s and steep 30 minutes, decoct secondary, each 0.5 hour, filter, at merging filtrate, be concentrated into about 1000ml, add sodium benzoate 2g, make it dissolve, cold preservation 12 hours again, filter, filtrate adding distil water is adjusted to 1000ml, stirs evenly subpackage and get final product.
embodiment 2
Important part of raw material that the present invention makes effective ingredient consists of:
Fructus Gardeniae 12, Radix Isatidis 20, Folium Isatidis 20, Semen Citri Reticulatae 18, Semen Litchi 15, Radix Gentianae 15, Rhizoma Corydalis 12, Radix Et Rhizoma Rhei 8, Fructus Liquidambaris 12, Radix Angelicae Sinensis 8, Radix Paeoniae Rubra 12
Preparation method is with embodiment 1.
embodiment 3
Important part of raw material that the present invention makes effective ingredient consists of:
Fructus Gardeniae 15, Radix Isatidis 25, Folium Isatidis 25, Semen Citri Reticulatae 20, Semen Litchi 20, Radix Gentianae 20, Rhizoma Corydalis 15, Radix Et Rhizoma Rhei 10, Fructus Liquidambaris 15, Radix Angelicae Sinensis 10, Radix Paeoniae Rubra 15
Preparation method is with embodiment 1.
embodiment 4
Important part of raw material that the present invention makes best effective ingredient consists of:
Fructus Gardeniae 15 Radix Isatidis 25 Folium Isatidis 20
Semen Citri Reticulatae 15 Semen Litchi 20 Radix Gentianae 15
Rhizoma Corydalis 15 Radix Et Rhizoma Rhei 5 Fructus Liquidambaris 15
Radix Angelicae Sinensis 10 Radix Paeoniae Rubra 15
Preparation method is with embodiment 1.
character:
This product is brown liquid, and have in a small amount through jolting, dispersible precipitation, feeble QI is fragrant, bitter and puckery flavor.
differentiate:
Get this product 20ml and add formic acid 80ml, stir evenly, leave standstill 30 minutes, filter, filtrate, evaporate to dryness, the residue 10ml that adds water makes it to dissolve, with chloroform extraction 3 times, each 20ml, discards chloroform solution, water layer again with water saturation, n-butanol extraction 3 times, each 20ml, merges n-butyl alcohol liquid, washs 2 times, each 25ml with n-butyl alcohol saturation water, after emulsifying, centrifugal in 4000 revs/min, divide and get n-butyl alcohol liquid, evaporate to dryness, residue adds methanol 1m makes dissolving, as need testing solution.Another extracting liquorice control medicinal material 1g, filters, filtrate evaporate to dryness.Every regulation that identification result is relevant under meeting mixture item.(Chinese Pharmacopoeia version in 2000 annex 1, fourth).
usage of the present invention and consumption:
Oral, a 100ml, 2 times on the one, temperatureization taking medicine after meal.
Untoward reaction: few patients occasionally has slight diarrhoea or times of defecation to increase, but disappears after drug withdrawal.
taboo and points for attention: 1. clothes are avoided to this Chinese medicine allergy sufferers; When 2. catching a cold, be cautious use of; 3. Aqua Folium Camelliae sinensis and congee with mung beans is avoided.
Monarch drug Fructus Gardeniae of the present invention, Radix Gentianae is the product that purging liver and gallbladder is damp and hot, finds that there is stronger spectrum resist antiinflammation according to modern pharmacological research.Ministerial drug is Folium Isatidis, and Radix Isatidis has stronger antivirus action.Adjuvant drug is Semen Citri Reticulatae, Semen Litchi, Radix Angelicae Sinensis, Radix Et Rhizoma Rhei, and Radix Paeoniae Rubra, has blood circulation promoting and blood stasis dispelling, the merit of dispersing swelling and dissipating binds.Making medicine Fructus Liquidambaris, is removing obstruction in the collateral to relieve pain.Therefore medicine card conforms to, treating both the principal and secondary aspects of a disease, brings out the best in each other.
Observation of curative effect of the present invention:
object, observe Chinese Herbs of the present invention.Method: adopt randomized blocks, treatment group 31 example, take traditional Chinese medicine treatment, and matched group 30 example, takes western medicine.Then red, swollen, hot, pain change and testis color ultrasound and the lab testing of observing patient local testis change.Result: treatment group total effective rate 87.1%, matched group total effective rate 76.7%.Conclusion, treatment by Chinese herbs acute orchitis is effective, reliably, and has no adverse reaction.And matched group (Western medicine), although effectively, there is clear and definite untoward reaction, as felt sick, vomiting, stomachache, diarrhoea and liver function injury.
clinical data
This is organized 61 examples and is clinic case, meets the diagnostic criteria of acute orchitis: eliminate wound male testical and break and acute hemorrhage in testis, testicular torsion; Epididymis, torsion of testicular appendage, testis disease and tumor of testis etc.8 ~ 54 years old age; Between the course of disease 3 days ~ 2 weeks; Wherein acute viral orchitis 13 example; Acute gonococcal orchitis 14 example, acute testicular 2 example after wound; Because of dressing tension (underwear) 3 example; Clinical manifestation has testis swelling, pain 32 example, heating 21 example, general malaise 32 example, one-sided painful and swollen testis 21 example, bilateral testes swells and ache 11 examples, blood routine examination, total white blood cells rising person 17 example, person 11 example on the low side, normal 4 examples, normal person 19 example of differential counting, neutrophilic granulocyte rising person 29 example, lymph grain is rising person 13 example carefully; Testis color Doppler checks, one-sided swollen testis 35 example, bilateral testes enlargement 26 example.
therapeutic Method:
Treatment group adopts Chinese medicine for oral administration treatment; Prescription: Fructus Gardeniae 15g, Folium Isatidis 15g, Radix Isatidis 20g, Semen Litchi 20g, Radix Gentianae 15g, Rhizoma Corydalis 15g, Semen Citri Reticulatae 20g, Fructus Liquidambaris 10g, Radix Paeoniae Rubra 15g, Radix Angelicae Sinensis 10g, Radix Et Rhizoma Rhei 5g.One day potion, soak by water, to 300ml, divides 2 decoction being taken warmly after meal.(being provided by the court Drug Manufacturing Room).Within 7 days, be a course for the treatment of, matched group, throws and takes Western medicine, the accurate word of Zithromax 0.25g(traditional Chinese medicines: H10960167) one day 1 time, double first.Continuous 7 days was 1 course for the treatment of.
Criterion of therapeutical effect cure: clinical disease, sign all disappear, testis color ultrasound and experimental check normal; Take a turn for the better: disease, sign disappear substantially, testis color ultrasound and lab testing are normally, invalid: disease.Sign is without being clearly better.Or delay or chronic testis patient, color ultrasound testis or epididymis ball scleroma person.
statistical method: data adopts X 2inspection, measurement data adopts t inspection.
Therapeutic outcome: treatment group 31 example, clinical cure 24 example, take a turn for the better 3 examples, invalid 4 examples, aggregate efficiency 87.1%, matched group 30 example, clinical cure 15 example, take a turn for the better 8 examples, invalid 7 examples, total effective rate 76.7%, treatment group is obviously better than matched group, and has no adverse reaction, and is worthy to be popularized.
discuss:
Acute orchitis morbidity is anxious, state of an illness weight, and patient suffering is unbearable, if treatment not in time or improper, then easily change acute orchitis or acute epididymitis into, protracted course of disease, easily recurs, and can cause sexual hypofunction.Spermatogenesis impairment is the one of the main reasons causing male sterility.Therefore, this disease answers active treatment acute, and taking Chinese medicine can heat-clearing and toxic substances removing, inducing diuresis and reducing edema, blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain.Radix Gentianae in side, Fructus Gardeniae, Radix Isatidis, Folium Isatidis are the product rushing down clearly dampness-heat of the liver, find that there is stronger antiviral and broad-spectrum antiseptic antiinflammation, Radix Paeoniae Rubra according to present pharmaceutical research.Radix Angelicae Sinensis blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, Semen Citri Reticulatae, Semen Litchi dispersing swelling and dissipating binds.Medicine card conforms to, and treating both the principal and secondary aspects of a disease, brings out the best in each other.
Acute orchitis pathogen and pathology of tcm has two: one for damp invasion of lower energizer, stagnation of QI-blood, and meridians intercept; Two is wound blood stasis, redyes evil poison, blood stasis heat-transformation, and both all can form abscess block, the diseases such as pain because of the corruption of victory meat.
The acute orchitis doctor trained in Western medicine cause of disease: the common cause of acute orchitis has be blood source infect at two: one, antibacterial, virus after systemic infection, and the pathogenic bacterium such as gonococcus to testis, after testicular infection, form swelling rapidly, pain through hematogenous spread; Two is traumatic infections, testis closure or open injury, easy secondary testicular infection, forms local red and swollen, pain.Because inflammatory infiltrate goes out, testis swelling, the intrinsic pressure increase of testis, can there is atrophy of testis in the infringement of testis contorted seminiferous tubules and fibrosis, produce essence and decline, impact fertility.
Early stage treatment in time is then protected on the contrary because of blocking-up morning autoimmune can seminiferous tubule immunologic injury, and then protection spermatogenesis, has the meaning of prevention male sterility.
Should also be noted that during treatment: acute stage should lie up, and holds up scrotum with cloth; Advise the refrigerant diet of patient, the scorching food such as diet pure wine, pungent, frying.

Claims (1)

1. treat a Chinese medicine for acute orchitis, its feature in: the important part of raw material of making effective ingredient consists of:
Fructus Gardeniae 10-15 Radix Isatidis 15-25 Folium Isatidis 15-25
Semen Citri Reticulatae 15-20 Semen Litchi 15-20 Radix Gentianae 10-20
Rhizoma Corydalis 10-15 Radix Et Rhizoma Rhei 5-10 Fructus Liquidambaris 10-15
Radix Angelicae Sinensis 5-10 Radix Paeoniae Rubra 10-15.
CN201410530217.3A 2014-10-10 2014-10-10 Traditional Chinese medicine for treating acute orchitis Pending CN104225038A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105582370A (en) * 2015-09-17 2016-05-18 干银荣 Traditional Chinese medicine for treating epididymitis
CN108272977A (en) * 2018-04-12 2018-07-13 广西中医药大学 A kind of anti-male testical inflammation drug and preparation method thereof containing Semen Litchi extract

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100998672A (en) * 2006-12-28 2007-07-18 江蕾 Oral traditional Chinese medicine for treating constipation type herpes zoster

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100998672A (en) * 2006-12-28 2007-07-18 江蕾 Oral traditional Chinese medicine for treating constipation type herpes zoster

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
李曰庆等: "中西医结合诊治男科病讲座第十四讲子痈", 《中国农村医学》 *
洪英杰等: "中西医结合治疗急性睾丸炎的疗效观察", 《辽宁中医杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105582370A (en) * 2015-09-17 2016-05-18 干银荣 Traditional Chinese medicine for treating epididymitis
CN108272977A (en) * 2018-04-12 2018-07-13 广西中医药大学 A kind of anti-male testical inflammation drug and preparation method thereof containing Semen Litchi extract

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