CN104220132B - Respiration tracking apparatus and radiation therapy system - Google Patents
Respiration tracking apparatus and radiation therapy system Download PDFInfo
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- CN104220132B CN104220132B CN201380004410.7A CN201380004410A CN104220132B CN 104220132 B CN104220132 B CN 104220132B CN 201380004410 A CN201380004410 A CN 201380004410A CN 104220132 B CN104220132 B CN 104220132B
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- 230000029058 respiratory gaseous exchange Effects 0.000 title claims abstract description 87
- 238000001959 radiotherapy Methods 0.000 title claims abstract description 18
- 238000004458 analytical method Methods 0.000 claims abstract description 30
- 230000000241 respiratory effect Effects 0.000 claims abstract description 29
- 230000001225 therapeutic effect Effects 0.000 claims description 10
- 230000036387 respiratory rate Effects 0.000 claims description 9
- 201000010099 disease Diseases 0.000 claims description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 3
- 229910052760 oxygen Inorganic materials 0.000 claims description 3
- 239000001301 oxygen Substances 0.000 claims description 3
- 230000005540 biological transmission Effects 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 abstract description 13
- 238000002560 therapeutic procedure Methods 0.000 abstract 7
- 230000036391 respiratory frequency Effects 0.000 abstract 1
- 210000000038 chest Anatomy 0.000 description 4
- 210000001015 abdomen Anatomy 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 230000003211 malignant effect Effects 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 1
- 230000035565 breathing frequency Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/113—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb occurring during breathing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computed tomography [CT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1064—Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
- A61N5/1069—Target adjustment, e.g. moving the patient support
- A61N5/107—Target adjustment, e.g. moving the patient support in real time, i.e. during treatment
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Dentistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Physiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
A respiration tracking apparatus (100) and a radiation therapy system, related to the field of radiation therapy. The respiration tracking apparatus (100) comprises: a respiration control module (110) that is connected to an analysis and comparison module (120) and is used for controlling an outputted respiratory flow and respiratory frequency, and for transmitting time trajectory coordinate values of a positional movement of a tumor and respiratory waveform and frequency of a patient to the analysis and comparison module (120); the analysis and comparison module (120) that is connected to a therapy control module (130), compares the respiratory waveform and frequency of the patient with respiratory waveform and frequency collected during planning and design, and, when the difference is less than or equal to a predetermined value, instructs the therapy control module (130) to control, on the basis of the time trajectory coordinate values of the positional movement of the tumor, a therapy apparatus (200) to conduct a therapy; and, the therapy control module (130) that controls, on the basis of the instruction of the analysis and comparison module (120), the therapy apparatus (200) to conduct the therapy. The respiration tracking apparatus (100) and the radiation therapy system are capable of tracking precisely and treating a tumor that moves in position due to respiration.
Description
Technical field
The invention belongs to the precise radiotherapy field in medical field, more particularly to a kind of breathing tracks of device and radiation
Treatment system.
Background technology
Precise radiotherapy be based on high-definition image detection means come be accurately positioned, put position, irradiation etc. one
The three dimensional treatment technology of change.Precise radiotherapy can reduce target area normal surrounding tissue complication probability, improve tumor area and shine
Dosage is penetrated, increases tumor control rate.But human tumor, particularly thorax and abdomen malignant can be moved with the respiratory movement of human body,
And irradiation field is geo-stationary, when this results in the exposure dosage of target area and its important normal structure of surrounding with plan
The accuracy for having significant difference, radiotherapy in the treatment is affected.So, doing the accurate radiation of tumour, particularly thorax and abdomen malignant
In treatment, respirometric harmful effect is reduced using breathing tracks of device and is necessary.
Existing breathing tracks of device, usually using the outer fixed signal body of human body, signage is gathered by high-speed camera
The characteristics of motion judge the breathing situation of lung；Or gather human body chest by installing cluster telescopic band in human chest
Fluctuating situation in portion's judges the breathing situation of lung.Required when breathing situation is gathered patient in air-breathing end or end-tidal collection doing
Breathing situation does treatment plan.The letter that the signal or cluster telescopic band gathered according to high-speed camera in treatment are gathered
Number come analyze patient whether reach end-tidal or air-breathing end, only patient end-tidal or air-breathing end it is relatively steady when, treatment
Equipment just start treatment, when patient start again at air-breathing or exhale when equipment stop treatment, so as to come realize breathing tracking.But
Such breathing tracks of device is discontinuity, the characteristic for not possessing real-time tracking, it is impossible to which accurate tracking treatment is due to breathing
The tumour for bringing position to move.
The content of the invention
It is an object of the invention to provide one kind breathing tracks of device and radiotherapy system, it is intended to solve prior art not
The problem that treatment carrys out the tumour of position movement due to breathing zone can accurately be tracked.
The present invention is achieved in that a kind of breathing tracks of device, including control of breathing module, analyses and comparison module and
Treatment control module, wherein：The control of breathing module, is connected to the analyses and comparison module, for the breathing of controlled output
Flow and respiratory rate, and the time locus coordinate value and patient respiration waveform and frequency of knub position movement are sent to described
Analyses and comparison module；The analyses and comparison module, is connected to the control of breathing module and the treatment control module, receives
The time locus coordinate value and the patient respiration waveform and frequency of the knub position movement that the control of breathing module sends
Rate, the respiratory waveform and frequency gathered during by the patient respiration waveform and frequency with plan design compares, as the patient
When the respiratory waveform and the difference of frequency gathered when respiratory waveform and frequency are with the plan design are less than or equal to preset value, refer to
Show that the treatment control module is treated according to the time locus coordinate value control therapeutic system that the knub position is moved；With
And the treatment control module, the analyses and comparison module is connected to, according to the instruction of the analyses and comparison module, according to described
The time locus coordinate value control therapeutic system of knub position movement is treated.
Preferably, the respiratory waveform that is gathered when the patient respiration waveform and frequency are with the plan design and frequency
When difference is more than preset value, the analyses and comparison module indicates the treatment control module to stop treatment.
Preferably, the control of breathing module further includes breathing supply logging modle, image scanning module and swells
Knurl position computation module, wherein：The breathing supply and logging modle, are connected to the knub position computing module, according to pre-
If respiratory flow and respiratory rate give patient supply oxygen, record the respiratory waveform and frequency of the patient, and by the disease
People's respiratory waveform and frequency are sent to the knub position computing module；And the image scanning module, it is connected to described swollen
Knurl position computation module, in the case where patient steadily breathes, image scan, and the patient's dynamic that will be scanned is carried out to patient
Image is sent to the knub position computing module.
Preferably, the knub position computing module, is connected to the breathing supply logging modle and the image is swept
Module is retouched, the patient respiration waveform and frequency and the image scan that the breathing supply and logging modle send is received
Patient's dynamic image that module sends, according to patient's dynamic image and the patient respiration waveform and frequency, meter
The time locus coordinate value of knub position movement of the patient in the case of this respiratory waveform and frequency is calculated, and will be described swollen
The time locus coordinate value and the patient respiration waveform and frequency of knurl position movement are sent to the analyses and comparison module.
Preferably, the image scan scope for image scan being carried out to patient was at least one complete respiratory rate cycle.
Preferably, the image scanning module is Dynamic CT.
Another object of the present invention is to provide a kind of radiotherapy system, including above-described breathing tracks of device.
Preferably, the instruction of the treatment control module of the therapeutic system in the breathing tracks of device is to disease
People is treated.
Breathing tracks of device and radiotherapy system that the present invention is provided, can accurately track treatment because breathing zone comes
The tumour of position movement.
Brief description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing
The accompanying drawing to be used needed for having technology description is briefly described, it should be apparent that, drawings in the following description are only this
Some embodiments of invention, for those of ordinary skill in the art, on the premise of not paying creative work, can be with
Other accompanying drawings are obtained according to these accompanying drawings.
Fig. 1 is the structured flowchart of the breathing tracks of device that one embodiment of the invention is provided；
Fig. 2 is the structured flowchart of the radiotherapy system that one embodiment of the invention is provided.
Specific embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, it is right below in conjunction with drawings and Examples
The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and
It is not used in the restriction present invention.
Fig. 1 is referred to, Fig. 1 is the structured flowchart of the breathing tracks of device that one embodiment of the invention is provided.As shown in figure 1,
Breathing tracks of device 100 includes：Control of breathing module 110, analyses and comparison module 120 and treatment control module 130.
Control of breathing module 110, is connected to analyses and comparison module 120, for the respiratory flow for controlling it to export and breathing
Frequency, and the time locus coordinate value and patient respiration waveform and frequency of the movement of patient's knub position are sent to analyses and comparison mould
Block 120.Control of breathing module 110 is further included：Breathing supply logging modle 111, image scanning module 113 and tumour position
Put computing module 115.
Breathing supply and logging modle 111, are connected to knub position computing module 115, according to default respiratory flow and
Respiratory rate supplies oxygen to patient, records the respiratory waveform and frequency of patient, and the patient respiration waveform and frequency that will be recorded
Rate is sent to knub position computing module 115.
Image scanning module 113, is connected to knub position computing module 115, in the case where patient steadily breathes, to disease
People carries out image scan, and the patient's dynamic image that will be scanned is sent to knub position computing module 115, wherein, image is swept
It was at least one complete respiratory rate cycle to retouch scope, and the complete respiratory rate cycle refers to a complete expiration plus air-breathing
Process, image scanning module 113 can be Dynamic CT.
Knub position computing module 115, is connected to breathing supply logging modle 111 and image scanning module 113, receives
The patient that the patient respiration waveform and frequency and image scanning module 113 that breathing supply and logging modle 111 send send moves
State image, according to patient's dynamic image and patient respiration waveform and frequency, calculates patient in this respiratory waveform and frequency feelings
The time locus coordinate value of knub position movement under condition, and this time trajectory coordinates value and patient respiration waveform and frequency are sent
To analyses and comparison module 120.
Analyses and comparison module 120, is connected to knub position computing module 115 and treatment control module 130, receives tumour
The time locus coordinate value and patient respiration waveform and frequency of the knub position movement that position computation module 115 sends, by patient
The respiratory waveform and frequency gathered when respiratory waveform and frequency are with plan design compare, when patient respiration waveform and frequency and meter
When the difference of the respiratory waveform and frequency that delineate timing collection is less than or equal to preset value, analyses and comparison module 120 indicates treatment
Control module 130 is treated according to the time locus coordinate value control therapeutic system that knub position is moved.When patient respiration ripple
When the respiratory waveform and the difference of frequency gathered when shape and frequency are with plan design are more than preset value, analyses and comparison module 120 refers to
Show that treatment control module 130 stops treatment, patient respiration situation to be adjusted after making its breathing stabilization, is further continued for treatment.
Treatment control module 130, is connected to analyses and comparison module 120, according to the instruction of analyses and comparison module 120, according to
The time locus coordinate value control therapeutic system of knub position movement is treated.
That is, during whole treatment, the patient respiration that analyses and comparison module 120 will be collected incessantly
The respiratory waveform and frequency gathered when waveform and frequency are with plan design compare, if (that is, error is allowed beyond preset value
Value) by stopped treatment.
Fig. 2 is the structured flowchart of the radiotherapy system that one embodiment of the invention is provided.As shown in Fig. 2 radiotherapy system
System includes breathing tracks of device 100 and therapeutic system 200, and therapeutic system 200 treats control according in breathing tracks of device 100
The instruction of module 130 is treated to patient.
Breathing tracks of device and radiotherapy system provided by the present invention, can accurately track treatment due to breathing zone
Carry out the tumour of position movement.
Presently preferred embodiments of the present invention is the foregoing is only, is not intended to limit the invention, it is all in essence of the invention
Any modification, equivalent and improvement made within god and principle etc., should be included within the scope of the present invention.
Claims (8)
1. it is a kind of to breathe tracks of device, it is characterised in that including control of breathing module, analyses and comparison module and treatment control mould
Block, wherein：
The control of breathing module, is connected to the analyses and comparison module, for the respiratory flow and respiratory rate of controlled output,
And the time locus coordinate value and patient respiration waveform and frequency of knub position movement are sent to the analyses and comparison module；
The analyses and comparison module, is connected to the control of breathing module and the treatment control module, receives the breathing
The time locus coordinate value and the patient respiration waveform and frequency of the knub position movement that control module sends, will be described
The respiratory waveform and frequency gathered when patient respiration waveform and frequency are with plan design compare, when the patient respiration waveform and
When the respiratory waveform and the difference of frequency gathered when frequency is with the plan design are less than or equal to preset value, the treatment is indicated
Control module is treated according to the time locus coordinate value control therapeutic system that the knub position is moved；And
The treatment control module, is connected to the analyses and comparison module, according to the instruction of the analyses and comparison module, according to institute
The time locus coordinate value control therapeutic system for stating knub position movement is treated；
The control of breathing module further includes breathing supply logging modle and knub position computing module, wherein：It is described
Breathing supply and logging modle are connected to the knub position computing module, according to default respiratory flow and respiratory rate to disease
People supplies oxygen, records the respiratory waveform and frequency of the patient, and the patient respiration waveform and frequency is sent to described
Knub position computing module.
It is 2. as claimed in claim 1 to breathe tracks of device, it is characterised in that：
The respiratory waveform and the difference of frequency gathered when the patient respiration waveform and frequency are with the plan design are more than pre-
If during value, the analyses and comparison module indicates the treatment control module to stop treatment.
3. it is as claimed in claim 1 to breathe tracks of device, it is characterised in that the control of breathing module further includes image
Scan module, wherein：
The image scanning module, is connected to the knub position computing module, in the case where patient steadily breathes, to patient
Image scan is carried out, and the patient's dynamic image that will be scanned is sent to the knub position computing module.
It is 4. as claimed in claim 3 to breathe tracks of device, it is characterised in that：
The knub position computing module, is connected to breathing supply logging modle and the image scanning module, receives
What the patient respiration waveform and frequency and the image scanning module of the breathing supply and logging modle transmission sent
Patient's dynamic image, according to patient's dynamic image and the patient respiration waveform and frequency, calculates patient and exists
The time locus coordinate value of the knub position movement in the case of this respiratory waveform and frequency, and the knub position is moved
Time locus coordinate value and the patient respiration waveform and frequency be sent to the analyses and comparison module.
5. it is as claimed in claim 3 to breathe tracks of device, it is characterised in that the image scan model of image scan is carried out to patient
It was at least one complete respiratory rate cycle to enclose.
6. it is as claimed in claim 3 to breathe tracks of device, it is characterised in that the image scanning module is Dynamic CT.
7. a kind of radiotherapy system, it is characterised in that track dress including the breathing as any one of claim 1-6
Put.
8. radiotherapy system as claimed in claim 7, it is characterised in that：The therapeutic system is according to the breathing tracking dress
The instruction of the treatment control module in putting is treated to patient.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2013/071997 WO2014131178A1 (en) | 2013-02-28 | 2013-02-28 | Respiration tracking apparatus and radiation therapy system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104220132A CN104220132A (en) | 2014-12-17 |
| CN104220132B true CN104220132B (en) | 2017-05-24 |
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| CN201380004410.7A Active CN104220132B (en) | 2013-02-28 | 2013-02-28 | Respiration tracking apparatus and radiation therapy system |
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| CN (1) | CN104220132B (en) |
| WO (1) | WO2014131178A1 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016086976A1 (en) * | 2014-12-02 | 2016-06-09 | Brainlab Ag | Human body measurement using thermographic images |
| CN107126192B (en) * | 2017-04-18 | 2020-03-06 | 四川省肿瘤医院 | Tumor position real-time monitoring system and monitoring method thereof |
| CN110366389B (en) * | 2017-06-19 | 2023-03-03 | 深圳市奥沃医学新技术发展有限公司 | System and device for determining target point position by using radiotherapy equipment and radiotherapy equipment |
| WO2018232568A1 (en) * | 2017-06-19 | 2018-12-27 | 深圳市奥沃医学新技术发展有限公司 | Method for tracking and irradiating target using radiotherapy apparatus, device and radiotherapy apparatus |
| CN109363702B (en) * | 2018-09-29 | 2023-01-20 | 上海联影医疗科技股份有限公司 | Medical imaging method and system and radiation dose acquisition method and system |
| WO2020124583A1 (en) * | 2018-12-21 | 2020-06-25 | 四川省肿瘤医院 | Real-time tumor position monitoring system and monitoring method thereof |
| CN109965884A (en) * | 2019-04-19 | 2019-07-05 | 哈尔滨理工大学 | A kind of body surface respiratory movement measuring system based on acceleration transducer |
| CN110237446B (en) * | 2019-07-09 | 2024-05-03 | 冯丽娟 | Respiratory gating equipment for tumor radiotherapy |
| CN114052767B (en) * | 2022-01-14 | 2022-03-22 | 常州复睿特生物科技有限公司 | Lung cancer molecular marker detection device |
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| CN101076282A (en) * | 2004-09-30 | 2007-11-21 | 安科锐公司 | Dynamic tracking of moving targets |
| CN101843955A (en) * | 2010-03-30 | 2010-09-29 | 江苏瑞尔医疗科技有限公司 | Hybrid forecasting method for position signal of breath synchronous tracking system and forecaster |
| WO2012127724A1 (en) * | 2011-03-18 | 2012-09-27 | 三菱重工業株式会社 | Control device for radiation therapy device, processing method and programme for same |
| CN102908144A (en) * | 2011-08-03 | 2013-02-06 | 西门子公司 | Magnetic resonance imaging for therapy planning |
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| US20070000494A1 (en) * | 1999-06-30 | 2007-01-04 | Banner Michael J | Ventilator monitor system and method of using same |
| US8920333B2 (en) * | 2006-05-12 | 2014-12-30 | Yrt Limited | Method and device for generating of a signal that reflects respiratory efforts in patients on ventilatory support |
| CN101081177A (en) * | 2006-05-30 | 2007-12-05 | 深圳市一体医疗科技有限公司 | Method for real time tracking of knub position through radiotherapy |
| US7609810B2 (en) * | 2006-12-14 | 2009-10-27 | Byong Yong Yi | Treatment-speed regulated tumor-tracking |
| CN101623198A (en) * | 2008-07-08 | 2010-01-13 | 深圳市海博科技有限公司 | Real-time tracking method for dynamic tumor |
| WO2010108552A1 (en) * | 2009-03-27 | 2010-09-30 | Maquet Critical Care Ab | Peep regulation for a breathing apparatus |
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2013
- 2013-02-28 CN CN201380004410.7A patent/CN104220132B/en active Active
- 2013-02-28 WO PCT/CN2013/071997 patent/WO2014131178A1/en active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101076282A (en) * | 2004-09-30 | 2007-11-21 | 安科锐公司 | Dynamic tracking of moving targets |
| CN101843955A (en) * | 2010-03-30 | 2010-09-29 | 江苏瑞尔医疗科技有限公司 | Hybrid forecasting method for position signal of breath synchronous tracking system and forecaster |
| WO2012127724A1 (en) * | 2011-03-18 | 2012-09-27 | 三菱重工業株式会社 | Control device for radiation therapy device, processing method and programme for same |
| CN102908144A (en) * | 2011-08-03 | 2013-02-06 | 西门子公司 | Magnetic resonance imaging for therapy planning |
Also Published As
| Publication number | Publication date |
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| WO2014131178A1 (en) | 2014-09-04 |
| CN104220132A (en) | 2014-12-17 |
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