CN104258508B - Exact dose distributed modulation system and method in a kind of radiotherapy - Google Patents
Exact dose distributed modulation system and method in a kind of radiotherapy Download PDFInfo
- Publication number
- CN104258508B CN104258508B CN201410549658.8A CN201410549658A CN104258508B CN 104258508 B CN104258508 B CN 104258508B CN 201410549658 A CN201410549658 A CN 201410549658A CN 104258508 B CN104258508 B CN 104258508B
- Authority
- CN
- China
- Prior art keywords
- image
- target area
- real
- ray
- positioning system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The present invention relates to exact dose distributed modulation method and system in a kind of radiotherapy, when interval procedure puts position, obtains the four-dimensional conical beam CT image (4D CBCT) of patient, builds target area motion model in conjunction with respiratory movement signal；In interval procedure, by optical positioning system monitor in real time patient respiration motor message and patient's nonautonomy movable signal, by target area motion model fast prediction tumour shift position, real-time adjustment multi-diaphragm collimator leaf position, beam tightly tracking of knub is made precisely to be treated.Whole therapeutic process patient freely breathes, accelerator uninterruptedly goes out beam, reduces treatment time, while overcoming the dose error that patient respiration motion and nonautonomy movement bring in treatment, improves radiotherapy precision.
Description
Technical field
The present invention relates to radiotherapy equipment technical field of improvement, and in particular to exact dose distribution in a kind of radiotherapy
Modulating system and method.
Background technology
In radiation therapy process, the respiratory movement of patient and nonautonomy movement can cause the change of knub position, cause to swell
Knurl target area acceptable dose is not enough or normal structure organ crosses irradiation, increased tumor recurrence rate and irradiation complication incidence.For
Reduce and the uncertainty that brings, the side for clinically generally adopting are thrown in target dose due to respiratory movement and nonautonomy movement
Method one is that target area extends out method, fully covers patient respiration motion and non-autonomous motion band by delineating sufficiently large target area border
The tumour displacement range that comes, but this can make patient's normal structure receive more radiation exposures, and then it is bad to increase patient's appearance
The possibility of reaction；Two is respiratory gating technology, be hold one's breath in patient, breathing end or during certain specific respiratory cycle
Wait, radiotherapy is carried out to tumor region, as the motion of now tumour is less, therefore can effectively reduce the border of target area. its
Have the disadvantage that the breathing to patient and state there are strict requirements, a lot of cancer patients are unable to reach this requirement, meanwhile, this side
Method needs accelerator constantly to stop beam and go out beam, increased accelerator and goes out beam error, also increases the radiocurable time.At present
State-of-the-art dynamic radiotherapy technology, such as ejected wave knife, are that the tumor motion dynamic adjustment according to real-time detection in Patients During Radiotherapy is penetrated
Beam or the position of patient, make beam substantially aligned with tumour, thus can efficiently reduce the border of target area, greatly reduce to normal
The injury of tissue.However, being transported to tumour using interplantation label and X ray real time imagery method more than existing dynamic radiotherapy technology
Moving and being tracked, extra imaging dosage and intrusive mood injury is caused to patient.
Content of the invention
The purpose of the present invention be in existing radiation therapy technology cannot by quick, the noninvasive mode of one kind solve by
In the patient respiration motion problem inaccurate with the tumor target dose delivery that nonautonomy motion is caused, there is provided a kind of radiation
Exact dose distributed modulation system and method in treatment.
The technical solution used in the present invention is：
Exact dose distributed modulation system in a kind of radiotherapy, its are held to levy and are to include：Medical accelerator target source, leafy
Collimater, therapeutic bed, pulsed KV level X-ray production apparatus, X-ray flat panel detector, optical positioning system, PC server；Medical plus
Fast device target source is the x-ray photon source that high energy electron target practice is produced by bremsstrahlung effect；Multi-diaphragm collimator is accurate as beam
Straight device, forms predetermined beam direction by the position of real-time adjustment multi-leaf raster leaf sequence and the motion mode of whole machine displacement
Beam is treated with beam shape；Pulsed KV level X-ray production apparatus and X-ray flat panel detector project shadow as patient's two-dimensional x-ray
As harvester, continuous acquisition image in 360 ° of revolution spaces of accelerator；Optical positioning system, goes forward installed in accelerator
Side, for monitoring the respiratory movement signal and nonautonomy motor message of patient；Match somebody with somebody image collecting module, image in PC server
Processing module, target area motion real-time monitoring module, X-ray production apparatus driving interface, X ray image collection driving card, optical alignment letter
Number collection driving card, therapeutic bed driving interface, multi-diaphragm collimator driving interface, wherein image collecting module and X-ray production apparatus drive
Interface, X ray image collection driving card, optical alignment signals collecting driving card, image processing module connection, are responsible for four-dimension taper
Beam CT image collections and reconstruction；Image processing module is driven with image collecting module, target area motion real-time monitoring module, therapeutic bed
Interface connects, and is responsible for the correction of pendulum position and target area motion model builds；Target area motion real-time monitoring module and image processing module, light
Framing signal collection driving card, the connection of multi-diaphragm collimator driving interface is learned, is responsible for the monitor in real time of target area motion and leafy collimation
The real time location tracking of device；X-ray production apparatus interface is connected with image collecting module, pulsed KV level X-ray production apparatus, is responsible for image collection
Signal conversion between module and pulsed KV level X-ray production apparatus；X ray image collection driving card is put down with image collecting module, X ray
Partitioned detector connects, the signal conversion being responsible between image collecting module and X-ray flat panel detector；Optical alignment signals collecting is driven
Dynamic card is connected with image collecting module, target area motion real-time monitoring module, optical positioning system, is responsible for optical positioning system and shadow
As the signal conversion between acquisition module, target area motion real-time monitoring module；Therapeutic bed driving interface and image processing module, control
Bed connection is treated, the signal conversion being responsible between image processing module and therapeutic bed；Multi-diaphragm collimator driving interface is real with target area motion
When monitoring module, multi-diaphragm collimator connection, be responsible between target area motion real-time monitoring module and multi-diaphragm collimator signal conversion.
The optical positioning system is laser scanning alignment system, infrared laser alignment system or other optical alignment systems
System.The four-dimensional conical beam CT image gathered when image processing module is according to pendulum position and the respiratory movement letter of optical positioning system detection
Number building target area motion model, mathematic(al) representation is as follows：
Wherein,
TM(x,y,z,t,ISO)：In radiotherapy, isocentric motion is treated relative to medical accelerator in tumor target center
Side-play amount；
NI(t)：Patient's nonautonomy motion excursion amount；
A, b：Target area motion model initiation parameter；
Recorded during pendulum position is shared a common fate optical positioning system coordinate under phase with plan CT, is reference coordinate；
In treatment, share a common fate optical positioning system coordinate under phase with plan CT；
△t：System responds delay time, and the overall response including optical positioning system positioning and multi-diaphragm collimator displacement is prolonged
When；
The revised optical positioning system of system response time delay predicts respiratory movement signal；
R(t)：The respiratory movement signal of optical positioning system real-time monitoring；
R(△t)：System responds delay time internal respiration motor message variable quantity.
The target area motion model using with plan CT share a common fate optical positioning system under phase origin coordinates as reference
Coordinate, in radiotherapy, is calculated by the coordinate value of contrast optical positioning system Real-time Feedback under the specific respiratory phase
The tumor target side-play amount that the motion of patient's nonautonomy is caused.
Exact dose distributed modulation system in radiotherapy, the process of realization is：When carrying out pendulum position to patient in therapeutic bed,
Image collecting module sets rational acquisition parameter for different tumor locus, by pulsed X-ray production apparatus, X ray flat board
Detector and optical positioning system are gathered and rebuild four-dimensional conical beam CT image；Image processing module first by plan CT with
Phase four-dimension conical beam CT Image registration, calculates patient's pendulum position side-play amount, and is converted to therapeutic bed drive by therapeutic bed driving interface
Dynamic signal drives therapeutic bed adjustment patient location, at the same record now optical positioning system coordinate as start reference coordinate；So
The respiratory movement signal that is monitored according to four-dimensional conical beam CT image and optical positioning system afterwards builds target area respiratory movement model；?
Go out in beam treatment, motion real-time monitoring module in target area is breathed in conjunction with target area by optical positioning system real-time detection motor message
Motion model and optical positioning system start reference coordinate, calculate tumor target displacement in real time and the motion of patient's nonautonomy is inclined
Shifting amount, and these side-play amounts are converted to multi-diaphragm collimator amount of movement, control multi-diaphragm collimator is quickly made corresponding displacement and is rung
Should, realize that beam is irradiated to the real-time tracking of tumor target.
Present invention advantage compared with prior art is：
(1) exact dose distributed modulation method and system in a kind of radiotherapy of the invention, can be simultaneously to radiotherapy
In due to patient respiratory movement and nonautonomy move the tumor target motion excursion amount that causes and carry out monitor in real time, and plus
System response time delay correction is entered, it is achieved that multi-diaphragm collimator is irradiated to the real-time tracking of tumor target.
(2) after using the present invention, without the need for extending out to patient target region border, without the need for implantable marker thing, without the need in radiotherapy
During carry out the X ray real time imagery extra to patient, whole therapeutic process patient freely can breathe, and accelerator is uninterrupted
Go out beam, improve patient comfort, reduce treatment time.
(3) present invention not only can monitor in real time due to tumor target change in location caused by respiratory movement, while may be used also
The tumour displacement that Quantitative Monitoring compensation is brought due to the movement of patient's nonautonomy, the motion excursion amount according to tumor target are controlled in real time
Multi-diaphragm collimator processed adjusts beam direction, and the tumor motion of patient is compensated, so as to realize accurate dosage distribution.
Description of the drawings
Fig. 1 is exact dose distributed modulation system configuration schematic diagram；
Fig. 2 is that exact dose distributed modulation method realizes schematic flow sheet
Fig. 3 is exact dose distributed modulation system and method operation principle schematic diagram.
Specific embodiment
With reference to the accompanying drawings and detailed description the present invention is described further：
As shown in figure 1, exact dose distributed modulation system in the radiotherapy of the present invention, including medical accelerator target source 1,
Multi-diaphragm collimator 2, pulsed KV level X-ray production apparatus 3, X-ray flat panel detector 4, optical positioning system 5, therapeutic bed 6, high-performance
PC server 7；Wherein medical accelerator target source 1 is the x-ray photon source that high energy electron target practice is produced by bremsstrahlung effect；
Multi-diaphragm collimator 2 is shifted as beam collimation device, the position and whole machine that can pass through real-time adjustment multi-leaf raster leaf sequence
Motion mode forms predetermined beam direction and beam shape treatment beam；Pulsed KV level X-ray production apparatus 3 and the detection of X ray flat board
Device 4, can be in continuous acquisition image in 360 ° of revolution spaces of accelerator used as patient's two-dimensional x-ray projection image harvester；Light
It can be laser scanning alignment system, infrared laser alignment system or other optical positioning systems to learn alignment system 5, installed in plus
Fast device front upper place, for monitoring the respiratory movement signal and nonautonomy motor message of patient；Therapeutic bed 6 is manual, automatically double
Control therapeutic bed；Penetrate with image collecting module 8, image processing module 9, target area motion real-time monitoring module 10, X in PC server 7
Line machine interface 11, X ray image collection driving card 12, optical alignment signals collecting driving card 13, therapeutic bed driving interface 14, many
Leaf collimater driving interface 15, wherein image collecting module 8 gather driving card with X-ray production apparatus driving interface 11, X ray image
12nd, optical alignment signals collecting driving card 13, image processing module 9 connect, and are responsible for four-dimension conical beam CT image collection and reconstruction；
Image processing module 9 is connected with image collecting module 8, target area motion real-time monitoring module 10, therapeutic bed driving interface 6, is responsible for
Pendulum position is corrected and target area motion model builds；Target area motion real-time monitoring module 10 and image processing module 9, optical alignment signal
Collection driving card 13, multi-diaphragm collimator driving interface 15 connect, and are responsible for the monitor in real time of target area motion and the reality of multi-diaphragm collimator
When locating and tracking；X-ray production apparatus interface 11 is connected with image collecting module 8, pulsed KV level X-ray production apparatus 3, is responsible for image collection mould
Signal conversion between block 8 and pulsed KV level X-ray production apparatus 3；X ray image collection driving card 12 is penetrated with image collecting module 8, X
Line flat panel detector 4 connects, the signal conversion being responsible between image collecting module 8 and X-ray flat panel detector 4；Optical alignment is believed
Number collection driving card 13 is connected with image collecting module 8, target area motion real-time monitoring module 10, optical positioning system 5, responsible light
Learn alignment system 5 and the conversion of the signal between image collecting module 8, target area motion real-time monitoring module 10；Therapeutic bed drives and connects
Mouth 14 is connected with image processing module 9, therapeutic bed 6, the signal conversion being responsible between image processing module 9 and therapeutic bed 6；Leafy standard
Straight device driving interface 15 is connected with target area motion real-time monitoring module 10, multi-diaphragm collimator 2, is responsible for target area motion monitor in real time mould
Signal conversion between block 10 and multi-diaphragm collimator 2.
As shown in Fig. 2 a kind of exact dose distributed modulation method in radiotherapy, it is as follows which implements step：
When carrying out pendulum position to patient in therapeutic bed, image collecting module 8 sets rational for different tumor locus
Acquisition parameter, and driving card 12, optical alignment signals collecting driving card are gathered by X-ray production apparatus driving interface 11, X ray image
13 driving pulse formula KV level X-ray production apparatus 3, X-ray flat panel detector 4 and optical positioning system 5 gather serial two-dimensional x-ray projection
Data for projection of the respiratory movement signal generation of data and optical positioning system with respiratory phase mark, by classical FDK
(Feldkamp-Davis-Kress) cone beam ct reconstruction algorithm rebuilds patient's four-dimension conical beam CT image；Image processing module 9
First by planning CT with the four-dimension conical beam CT Image registration of same phase, registering mode is supported based on maximum mutual information quantity algorithm
Rigid Registration mode and the elastic registrating mode based on Demos algorithms, export patient's pendulum position side-play amount after registration, and by therapeutic bed
Driving interface 14 is converted to therapeutic bed drive signal and drives therapeutic bed adjustment patient location, while recording now optical positioning system
Coordinate is used as start reference coordinate；Then image processing module 9 is monitored according to four-dimensional conical beam CT image and optical positioning system
Respiratory movement signal build target area respiratory movement model, target area motion mathematical model expression formula is as follows：
Wherein,
TM(x,y,z,t,ISO)：In radiotherapy, isocentric motion is treated relative to medical accelerator in tumor target center
Side-play amount；
NI(t)：Patient's nonautonomy motion excursion amount；
A, b：Target area motion model initiation parameter；
Recorded during pendulum position is shared a common fate optical positioning system coordinate under phase with plan CT, is reference coordinate；
In treatment, share a common fate optical positioning system coordinate under phase with plan CT；
△t：System responds delay time, and the overall response including optical positioning system positioning and multi-diaphragm collimator displacement is prolonged
When；
The revised optical positioning system of system response time delay predicts respiratory movement signal；
R(t)：The respiratory movement signal of optical positioning system real-time monitoring；
R(△t)：System responds delay time internal respiration motor message variable quantity.
During beam is gone out, target area motion real-time monitoring module 10 passes through 5 real-time detection motor message of optical positioning system,
In conjunction with target area respiratory movement model and optical positioning system start reference coordinate, calculate tumor target displacement in real time and patient is non-
Activity side-play amount, and these side-play amounts are converted to multi-diaphragm collimator amount of movement, by multi-diaphragm collimator driving interface 15
Control multi-diaphragm collimator quickly makes corresponding dynamic respond, realizes that beam is irradiated to the real-time tracking of tumor target.
In a word, the present invention proposes a kind of accurate dosage distributed modulation system and method, and its basic thought is in radiotherapy
The relation that front first collection four-dimension conical beam CT image is set up between breathing state and tumour displacement, by setting up in Patients During Radiotherapy
Relation and obtain indirectly the motion of tumour to the real-time monitoring that respiratory movement and nonautonomy are moved, and according to tumor target
Motion excursion amount control multi-diaphragm collimator adjustment beam direction, the tumor motion of patient is compensated, accurate so as to realize
Dosage distribution.Compared with the conventional method, the method not only can be monitored due to knub position change caused by respiratory movement, with
When can also Quantitative Monitoring compensation due to the tumour displacement that brings of movement of patient's nonautonomy；And need not pass through in Patients During Radiotherapy
Implantable marker thing and X ray real time imagery obtain the position of tumour, therefore can avoid being imaged injury of the dosage to patient, realize
Without invasive accurate radiotherapy.
The technology contents of the non-detailed disclosure of the present invention adopt techniques known.
Claims (3)
1. exact dose distributed modulation system in a kind of radiotherapy, which is held to levy and is to include：Medical accelerator target source, leafy standard
Straight device, therapeutic bed, pulsed KV level X-ray production apparatus, X-ray flat panel detector, optical positioning system, PC server；Medical acceleration
Device target source is the x-ray photon source that high energy electron target practice is produced by bremsstrahlung effect；Multi-diaphragm collimator is used as beam collimation
Device, the motion mode shifted by the position of real-time adjustment multi-leaf raster leaf sequence and whole machine formed predetermined beam direction and
Beam shape treats beam；Pulsed KV level X-ray production apparatus and X-ray flat panel detector are used as patient's two-dimensional x-ray projection image
Harvester, continuous acquisition image in 360 ° of revolution spaces of accelerator；Optical positioning system, installed in accelerator front upper place,
For monitoring the respiratory movement signal and nonautonomy motor message of patient；Match somebody with somebody at image collecting module, image in PC server
Reason module, target area motion real-time monitoring module, X-ray production apparatus driving interface, X ray image collection driving card, optical alignment signal
Collection driving card, therapeutic bed driving interface, multi-diaphragm collimator driving interface, wherein image collecting module are driven with X-ray production apparatus and are connect
Mouth, X ray image collection driving card, optical alignment signals collecting driving card, image processing module connection, are responsible for four-dimension pencil-beam
CT image collections and reconstruction；Image processing module drives and connects with image collecting module, target area motion real-time monitoring module, therapeutic bed
Mouth connection, is responsible for the correction of pendulum position and target area motion model and builds；Target area motion real-time monitoring module and image processing module, optics
Framing signal collection driving card, the connection of multi-diaphragm collimator driving interface, are responsible for monitor in real time and the multi-diaphragm collimator of target area motion
Real time location tracking；X-ray production apparatus interface is connected with image collecting module, pulsed KV level X-ray production apparatus, is responsible for image collection mould
Signal conversion between block and pulsed KV level X-ray production apparatus；X ray image collection driving card and image collecting module, X ray flat board
Detector connects, the signal conversion being responsible between image collecting module and X-ray flat panel detector；Optical alignment signals collecting drives
Card is connected with image collecting module, target area motion real-time monitoring module, optical positioning system, is responsible for optical positioning system and image
Signal conversion between acquisition module, target area motion real-time monitoring module；Therapeutic bed driving interface and image processing module, treatment
Bed connection, the signal conversion being responsible between image processing module and therapeutic bed；Multi-diaphragm collimator driving interface is with target area motion in real time
Monitoring module, multi-diaphragm collimator connection, the signal conversion being responsible between target area motion real-time monitoring module and multi-diaphragm collimator；
The four-dimensional conical beam CT image gathered when the image processing module is according to pendulum position and the breathing of optical positioning system detection
Building target area motion model, mathematic(al) representation is as follows for motor message：
NI(t)=P(Rconst,t)-P(Rconst,tct)(2)
Wherein,
TM(x,y,z,t,ISO)：In radiotherapy, isocentric motion excursion is treated relative to medical accelerator in tumor target center
Amount；
NI(t)：Patient's nonautonomy motion excursion amount；
A, b：Target area motion model initiation parameter；
P(Rconst,tct)：Recorded during pendulum position is shared a common fate optical positioning system coordinate under phase with plan CT, is reference coordinate；
P(Rconst,t)：In treatment, share a common fate optical positioning system coordinate under phase with plan CT；
△t：System responds delay time, including optical positioning system positioning and the overall response time delay of multi-diaphragm collimator displacement；
The revised optical positioning system of system response time delay predicts respiratory movement signal；
R(t)：The respiratory movement signal of optical positioning system real-time monitoring；
R(△t)：System responds delay time internal respiration motor message variable quantity.
2. exact dose distributed modulation system in a kind of radiotherapy according to claim 1, which is held to levy and is：The light
It is laser scanning alignment system, infrared laser alignment system or other optical positioning systems to learn alignment system.
3. exact dose distributed modulation system in a kind of radiotherapy according to claim 1, it is characterised in that the target
Area's motion model using with plan CT share a common fate optical positioning system under phase origin coordinates as reference coordinate, in radiotherapy
In, the motion of patient's nonautonomy is calculated by the coordinate value of contrast optical positioning system Real-time Feedback under the specific respiratory phase
The tumor target side-play amount for causing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410549658.8A CN104258508B (en) | 2014-10-16 | 2014-10-16 | Exact dose distributed modulation system and method in a kind of radiotherapy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410549658.8A CN104258508B (en) | 2014-10-16 | 2014-10-16 | Exact dose distributed modulation system and method in a kind of radiotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104258508A CN104258508A (en) | 2015-01-07 |
| CN104258508B true CN104258508B (en) | 2017-03-15 |
Family
ID=52150157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410549658.8A Active CN104258508B (en) | 2014-10-16 | 2014-10-16 | Exact dose distributed modulation system and method in a kind of radiotherapy |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104258508B (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104873217A (en) * | 2015-05-07 | 2015-09-02 | 管迪 | Ct scanner shielding device |
| CN105617535A (en) * | 2015-12-24 | 2016-06-01 | 上海联影医疗科技有限公司 | Dose distribution estimation method and sub-field optimization method |
| US10293184B2 (en) * | 2016-01-29 | 2019-05-21 | Elekta Ltd. | Therapy control using motion prediction |
| CN108853753B (en) * | 2016-09-30 | 2022-02-18 | 上海联影医疗科技股份有限公司 | Tumor real-time monitoring device and radiotherapy system |
| WO2018232566A1 (en) * | 2017-06-19 | 2018-12-27 | 深圳市奥沃医学新技术发展有限公司 | Method for determining target positions using radiotherapy apparatus, device and radiotherapy apparatus |
| CN110678224B (en) * | 2017-06-19 | 2022-05-13 | 深圳市奥沃医学新技术发展有限公司 | Device for tracking and irradiating target spot by using radiotherapy equipment and radiotherapy equipment |
| CN107096135A (en) * | 2017-06-22 | 2017-08-29 | 苏州奥特科然医疗科技有限公司 | Mobile detecting system and method |
| CN107261341A (en) * | 2017-07-12 | 2017-10-20 | 江西省肿瘤医院 | Patient body displacement detector in a kind of thorax and abdomen malignant radiation therapy process |
| JP7090451B2 (en) * | 2018-03-29 | 2022-06-24 | 住友重機械工業株式会社 | Charged particle beam therapy device |
| CN109363707B (en) * | 2018-11-15 | 2020-05-29 | 合肥中科离子医学技术装备有限公司 | Respiratory gating and CT image fusion image guiding device and method thereof |
| CN111388882B (en) * | 2020-03-26 | 2021-06-15 | 山东省肿瘤防治研究院（山东省肿瘤医院） | Method for dynamically adjusting radiation angle and dose according to movement of tumor |
| CN111437520B (en) * | 2020-04-03 | 2021-07-20 | 山东省肿瘤防治研究院（山东省肿瘤医院） | Method for synchronously calculating radiotherapy beam angle in real time in radiotherapy |
| CN111557676B (en) * | 2020-05-13 | 2023-12-19 | 山东省肿瘤防治研究院（山东省肿瘤医院） | System and equipment for dynamically adjusting target area position by tumor change in radiotherapy process |
| CN112843503A (en) * | 2021-01-29 | 2021-05-28 | 中国人民解放军陆军军医大学第二附属医院 | Radiotherapy in-vivo dose monitoring method |
| CN113101547B (en) * | 2021-04-14 | 2023-06-06 | 李夏东 | Dose reconstruction device based on tumor motion tracking and radiotherapy |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103143124A (en) * | 2013-04-06 | 2013-06-12 | 成都威铭科技有限公司 | Noninvasive radiotherapy system for robot |
| EP2679277A1 (en) * | 2012-06-28 | 2014-01-01 | Ion Beam Applications | Apparatus and method for conformal particle radiation therapy of a moving target |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101972515B (en) * | 2010-11-02 | 2012-05-09 | 华中科技大学 | Auxiliary radiotherapy mattress system guided by images and breath |
-
2014
- 2014-10-16 CN CN201410549658.8A patent/CN104258508B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2679277A1 (en) * | 2012-06-28 | 2014-01-01 | Ion Beam Applications | Apparatus and method for conformal particle radiation therapy of a moving target |
| CN103143124A (en) * | 2013-04-06 | 2013-06-12 | 成都威铭科技有限公司 | Noninvasive radiotherapy system for robot |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104258508A (en) | 2015-01-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104258508B (en) | Exact dose distributed modulation system and method in a kind of radiotherapy | |
| CN106039576B (en) | Portal dosimetry system, device and method | |
| JP5338000B1 (en) | Real-time 3D radiotherapy device | |
| JP6181459B2 (en) | Radiation therapy system | |
| EP2223720B1 (en) | Radiation therapy planning device | |
| US9616249B2 (en) | Radiotherapy control apparatus and radiotherapy control program | |
| US6535574B1 (en) | Patient positioning system employing surface photogrammetry and portal imaging | |
| US8803910B2 (en) | System and method of contouring a target area | |
| CN113164132A (en) | Apparatus and method for scalable field of view imaging using multi-source system | |
| CN102824693B (en) | System for verifying radiotherapy plan before online therapy | |
| US9968321B2 (en) | Method and imaging system for determining a reference radiograph for a later use in radiation therapy | |
| JP4981966B2 (en) | Radiotherapy apparatus control method and radiotherapy apparatus control apparatus | |
| US20170007850A1 (en) | Image-guided radiotherapy | |
| CN104220132B (en) | Respiration tracking apparatus and radiation therapy system | |
| CN108853753B (en) | Tumor real-time monitoring device and radiotherapy system | |
| CN102670234B (en) | Gamma radiation beam position verifying device and method | |
| CN103845816A (en) | Radiotherapy system and real-time monitoring method thereof | |
| JP2010187991A (en) | Bed positioning system, radiotherapy system and bed positioning method | |
| Loo Jr et al. | Motion management and image guidance for thoracic tumor radiotherapy: clinical treatment programs | |
| CN103706042B (en) | Four-dimensional tracking radiotherapy system | |
| CN109011211B (en) | Four-dimensional single-source gamma knife focus tracking and positioning system | |
| JP5566854B2 (en) | Radiotherapy apparatus control apparatus and radiotherapy apparatus control method | |
| CN116867547A (en) | Portal monitoring method, radiotherapy equipment, display device and system | |
| US20220126119A1 (en) | Radiation therapy apparatus and radiation therapy method | |
| WO2019159273A1 (en) | Radiation therapy device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |