CN102670234B - Gamma radiation beam position verifying device and method - Google Patents
Gamma radiation beam position verifying device and method Download PDFInfo
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- CN102670234B CN102670234B CN2012101526509A CN201210152650A CN102670234B CN 102670234 B CN102670234 B CN 102670234B CN 2012101526509 A CN2012101526509 A CN 2012101526509A CN 201210152650 A CN201210152650 A CN 201210152650A CN 102670234 B CN102670234 B CN 102670234B
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Abstract
The invention relates to a gamma radiation beam position verifying device and a method. The method comprises the following steps of: reconfiguring a CT (Computed Tomography) image to obtain a DDR (Double Data Rate) image containing a positioning mark; determining a tumor treating coordinate according to the DDR image, wherein an X photosphere tube and an imaging assembly are respectively mounted on a gamma radiation head and an arc-shaped rail; respectively imaging a patient tumor region by the X photosphere tube and the imaging assembly from different angles to obtain at least two DR (Digital Radiography) images from the different angles, wherein the DR image contains a mark image; reestablishing the CT image of a patient by an upper computer to generate the DDR image; converting a coordinate of the positioning mark into a treating coordinate by the upper computer according to at least two DR images; then carrying out matching calculation on the treating coordinate and the coordinate of the positioning mark of the DDR image of the corresponding angle to obtain a positioning parameter; and repositioning a tumor according to the positioning parameter by the upper computer. The gamma radiation beam position verifying device and the method disclosed by the invention can enable an irradiation field to tightly follow a target region by adjusting treating conditions according to the change of an organ position, so as to do accurate treating with the real meanings.
Description
Technical field
The present invention relates to a kind of pendulum position demo plant and method, relate in particular to a kind of gamma radiation pendulum position demo plant and method.
Background technology
When adopting gamma radiation tumor treatment equipment treatment tumor, usually first patient's tumor locus is shone CT,, by the reconstruction to the CT image, diagnose location, obtain knub position, then according to knub position, formulate treatment plan.Usually after oncotherapy plan a period of time, sick talent conference is again gone up the gamma radiation tumor treatment equipment and is treated, but can change because breathing and vermicular movement, daily pendulum bit error, target area contraction etc. cause knub position, thereby cause variation that Radiotherapy dosimetry distributes and the change for the treatment of plan.Existing gamma radiation tumor treatment equipment redefines knub position from an angle usually, the degree of accuracy that its knub position is determined is good for a long time, can not make irradiation field tightly " follow " target area according to the variation adjustment treatment condition of organ site, can not accomplish accurate treatment truly.
Summary of the invention
The technical problem that the present invention solves is: build a kind of gamma radiation pendulum position demo plant and method, overcoming prior art can not make irradiation field tightly " follow " target area according to the variation adjustment treatment condition of organ site, can not accomplish the technical problem of accurate treatment truly.
technical scheme of the present invention is: build a kind of gamma radiation pendulum position demo plant, comprise the gamma radiation head that gamma ray occurs, be arranged on the telltale mark that patient body-surface carries out tumor-localizing, send the X-ray bulb of imaging X-ray, the image-forming assembly that coordinates the imaging of described X-ray bulb, arc track, carry out the host computer of date processing, described gamma radiation head moves on described arc track, described X-ray bulb and described image-forming assembly are arranged on respectively on described gamma radiation head and described arc track, described X-ray bulb and described image-forming assembly obtain at least two DR images to the imaging from different perspectives of patient tumors zone respectively in different angles, contain marking image in described DR image, described host computer generates the DDR image according to patient's CT image reconstruction, described host computer is the treatment coordinate according at least two DR images with specifically labelled Coordinate Conversion, then the coordinate that will treat the DDR framing labelling of coordinate and described corresponding angle mates calculating, and obtain positional parameter, described host computer is reorientated tumor according to positional parameter.
Further technical scheme of the present invention is: described image-forming assembly is flat panel detector.
Further technical scheme of the present invention is: described host computer comprises the positioning unit of reorientating, and described positioning unit comprises that the threshold values that threshold values is set arranges module.
Further technical scheme of the present invention is: described telltale mark is a plurality of, and described a plurality of telltale marks are separately fixed at patient's diverse location with it, at multiple the above telltale marks of DR image of described shooting unit photographs, does not overlap mutually.
Further technical scheme of the present invention is: described host computer comprises the matching unit that mates calculating, described matching unit with a plurality of telltale marks respectively the specifically labelled coupling result of calculation corresponding with described DDR image average, get its average as final coupling result of calculation.
Technical scheme of the present invention is: a kind of gamma radiation device pendulum position verification method is provided, described pendulum position demo plant comprises gamma radiation head that gamma ray occurs, be arranged on image-forming assembly, the arc track of the telltale mark that patient body-surface carries out tumor-localizing, the X-ray bulb that sends the imaging X-ray, the imaging of the described X-ray bulb of cooperation, described gamma radiation head moves on described arc track, described X-ray bulb and described image-forming assembly are arranged on respectively on described gamma radiation head and described arc track, and described gamma radiation device pendulum position verification method comprises the steps:
Telltale mark is set: telltale mark is fixedly installed on it the patient;
Rebuild the DDR image: contain specifically labelled CT image reconstruction according to shooting and generate the DDR image;
Take the DR image: mobile described X-ray bulb and described image-forming assembly, respectively the imaging from different perspectives of patient tumors zone is obtained at least two DR images, contain marking image in described DR image;
Coupling is calculated: be the treatment coordinate according to the Coordinate Conversion of at least two DR framing labellings, the coordinate that then will treat the DDR framing labelling of coordinate and described corresponding angle mates and calculates coupling result of calculation;
Obtain positional parameter: according to coupling result of calculation and the definite tumor coordinate of described treatment plan, obtain positional parameter;
Location: tumor is reorientated according to described positional parameter.
Further technical scheme of the present invention is: in the telltale mark step is set, described telltale mark is a plurality of, described a plurality of telltale mark is separately fixed at patient's diverse location with it, at multiple the above telltale marks of DR image of described shooting unit photographs, does not overlap mutually.
Further technical scheme of the present invention is: in the coupling calculation procedure, with a plurality of telltale marks respectively the specifically labelled coupling result of calculation corresponding with described DDR image average, get its average as final coupling result of calculation.
Further technical scheme of the present invention is: in rebuilding the DDR image step, the central point of described CT image of using carries out the DDR image reconstruction as the center of DRR image.
Further technical scheme of the present invention is: in positioning step, also comprise the threshold values of reorientating target coordinate is set, reorientate target coordinate by positional parameter and threshold values, when positional parameter is outside the threshold values scope, adjusts target position and reorientate target coordinate; When positional parameter is in the threshold values scope, with the positional parameter compensation, tumor is reorientated.
technique effect of the present invention is: build a kind of gamma radiation pendulum position demo plant and method, by the CT image reconstruction is obtained to contain specifically labelled DDR image, determine the oncotherapy coordinate according to the DDR image, described X-ray bulb and described image-forming assembly are arranged on respectively on described gamma radiation head and described arc track, described X-ray bulb and described image-forming assembly obtain at least two DR images to the imaging from different perspectives of patient tumors zone respectively in different angles, contain marking image in described DR image, described host computer generates the DDR image according to patient's CT image reconstruction, described host computer is the treatment coordinate according at least two DR images with specifically labelled Coordinate Conversion, then the coordinate that will treat the DDR framing labelling of coordinate and described corresponding angle mates calculating, and obtain positional parameter, described host computer is reorientated tumor according to positional parameter.The present invention's a kind of gamma radiation device pendulum position verification method and system, can make irradiation field tightly " follow " target area according to the variation adjustment treatment condition of organ site, accomplishes accurate treatment truly.
Description of drawings
Fig. 1 is structural representation of the present invention.
Fig. 2 is flow chart of the present invention.
The specific embodiment
Below in conjunction with specific embodiment, technical solution of the present invention is further illustrated.
as shown in Figure 1, the specific embodiment of the present invention is: build a kind of gamma radiation pendulum position demo plant, comprise the gamma radiation head 1 that gamma ray occurs, be arranged on the telltale mark that patient body-surface carries out tumor-localizing, send the X-ray bulb 2 of imaging X-ray, the image-forming assembly 3 that coordinates the imaging of described X-ray bulb, arc track 5, carry out the host computer (not shown) of date processing, described gamma radiation head 1 moves on described arc track 5, described X-ray bulb 2 and described image-forming assembly 3 are arranged on respectively on described gamma radiation head 1 and described arc track 5, described X-ray bulb 2 and described image-forming assembly 3 obtain at least two DR images to the imaging from different perspectives of patient tumors zone respectively in different angles, contain marking image in described DR image, described host computer generates the DDR image according to patient's CT image reconstruction, described host computer is the treatment coordinate according at least two DR images with specifically labelled Coordinate Conversion, then the coordinate that will treat the DDR framing labelling of coordinate and described corresponding angle mates calculating, and obtain positional parameter, described host computer is reorientated tumor according to positional parameter.
As shown in Figure 1, the specific embodiment of the invention process is as follows: the patient is placed on therapeutic bed,, by the CT image reconstruction is obtained to contain specifically labelled DDR image, according to the DDR image, determines the oncotherapy coordinate, formulate treatment plan.described gamma radiation head 1 moves on described arc track 5, described X-ray bulb 2 and described image-forming assembly 3 are arranged on respectively on described gamma radiation head 1 and described arc track 5, described X-ray bulb 2 and described image-forming assembly 3 obtain at least two DR images to the imaging from different perspectives of patient tumors zone respectively in different angles, contain marking image in described DR image, described host computer generates the DDR image according to patient's CT image reconstruction, described host computer is the treatment coordinate according at least two DR images with specifically labelled Coordinate Conversion, then the coordinate that will treat the DDR framing labelling of coordinate and described corresponding angle mates calculating, and obtain positional parameter, described host computer is reorientated tumor according to positional parameter.In specific embodiment, described image-forming assembly 3 is flat panel detector.Described arc track 5 is arranged on frame.
These two DR images are mated calculating with the DRR image of corresponding angle respectively, and detailed process is as follows:
Described matching unit 3 is the treatment coordinate according at least two DR images with specifically labelled Coordinate Conversion:
Wherein: a is for the treatment focus to the distance between flat panel detector, and b is the distance between radiation head and flat panel detector;
(x
3, y
3) for telltale mark point coordinates conversion in the DR image under angle [alpha] comes, its coordinate system, take picture centre as initial point, is to the right the x axle, upwards is the y axle,
(x
1, y
1) be the coordinate of telltale mark point DR image mid point under angle [alpha];
(X
3, Y
3) for telltale mark DR image mid point coordinate transform under angle beta comes, its coordinate system, take picture centre as initial point, is to the right the x axle, upwards is the y axle:
(X
1, Y
1) be the coordinate of telltale mark point DR image mid point under angle beta.
Thus, obtain this specifically labelled treatment coordinate (x, y, z).DDR image specifically labelled according to this, this specifically labelled treatment coordinate (x, y, z) is subtracted each other respectively with the three-dimensional coordinate of this specifically labelled DDR image, obtain the coordinate difference of the three-dimensional coordinate of this telltale mark treatment coordinate (x, y, z) and this specifically labelled DDR image, it is patient's positional parameter, then, described positioning unit 5 is increased to this positional parameter on the corresponding coordinate of DDR image tumor coordinate, obtain the new treatment coordinate of tumor, with the treatment coordinate that tumor is new, tumor is reorientated.
In the preferred embodiment for the present invention, described telltale mark is a plurality of, and described a plurality of telltale marks are separately fixed at patient's diverse location with it, and 2 multiple the above telltale marks of DR image of taking do not overlap mutually in described shooting unit.Described matching unit 3 with a plurality of telltale marks respectively the specifically labelled coupling result of calculation corresponding with described DDR image average, get its average as final coupling result of calculation.Detailed process is as follows: if telltale mark is a plurality of, calculate respectively, obtained the treatment coordinate of this point by each telltale mark, then draw respectively specifically labelled coordinate difference separately, get the average of coordinate difference as positional parameter, then, described positioning unit 5 is increased to this positional parameter on the corresponding coordinate of DDR image tumor coordinate, obtain the new treatment coordinate of tumor, with the treatment coordinate that tumor is new, tumor is reorientated.Can obtain like this locating more accurately.
As shown in Figure 1, the preferred embodiment of the present invention is: described X-ray bulb 2 is arranged on described gamma radiation head 1, described X-ray bulb 2 and described gamma radiation head 1 connect by coupling assembly 4, described image-forming assembly 3 is arranged on described arc track 5, during use, thereby mobile described gamma radiation head 1 drives described X-ray bulb 2 and moves, and after mobile described image-forming assembly 3, the X-ray line that described X-ray bulb 2 is sent pass patient's patient part, the relative described image-forming assembly 3 of arrival carries out imaging.Two positions (60 °, 120 °) of 60 ° of differing in appointment obtain respectively two groups of X-ray DR images.The present invention takes full advantage for the treatment of head rotation arcing and drives image dash receiver synchronous rotary, the arbitrarily angled X-ray DR image that obtains within the specific limits.
As shown in Figure 2, the preferred embodiment of the present invention is: in positioning step, also comprise the threshold values of reorientating target coordinate is set, by positional parameter and threshold values, reorientate target coordinate, when positional parameter is outside the threshold values scope, adjusts target position and reorientate target coordinate; When positional parameter is in the threshold values scope, with the positional parameter compensation, tumor is reorientated.
technical scheme of the present invention is: a kind of gamma radiation device pendulum position verification method is provided, described pendulum position demo plant comprises the gamma radiation head 1 that gamma ray occurs, be arranged on the telltale mark that patient body-surface carries out tumor-localizing, send the X-ray bulb 2 of imaging X-ray, the image-forming assembly 3 that coordinates the imaging of described X-ray bulb, arc track 5, described gamma radiation head 1 moves on described arc track 5, described X-ray bulb 2 and described image-forming assembly 3 are arranged on respectively on described gamma radiation head 1 and described arc track 5, described gamma radiation device pendulum position verification method comprises the steps:
Step 100: telltale mark is set, that is, telltale mark is fixedly installed on it the patient.
Step 200: rebuild the DDR image: contain specifically labelled CT image reconstruction according to shooting and generate the DDR image.Detailed process is as follows: because telltale mark is fixedly installed on it the patient, contain telltale mark in the CT image, build three-dimensional system of coordinate, contain specifically labelled CT image reconstruction according to shooting and generate the DDR image, it is rebuild on the DDR image that generates, and telltale mark and knub position obtain respectively its coordinate in this three-dimensional system of coordinate, and then treatment planning systems is made treatment plan, namely the obtain medical treatment three-dimensional coordinate of target spot, telltale mark also has the three-dimensional coordinate in this three-dimensional system of coordinate.In process of reconstruction, the central point of described CT image of using carries out the DDR image reconstruction as the center of DRR image.
Step 300: take the DR image, that is: move described X-ray bulb and described image-forming assembly, take from different perspectives respectively at least two, patient tumors zone DR image.
Step 400: coupling is calculated, and is the treatment coordinate according to the Coordinate Conversion of at least two DR framing labellings that is:, and the coordinate that then will treat the DDR framing labelling of coordinate and described corresponding angle mates and calculates coupling result of calculation.
Detailed process is as follows: according at least two DR images, specifically labelled Coordinate Conversion is the treatment coordinate:
Wherein: a is for the treatment focus to the distance between flat panel detector, and b is the distance between radiation head and flat panel detector;
(x
3, y
3) for telltale mark point coordinates conversion in the DR image under angle [alpha] comes, its coordinate system, take picture centre as initial point, is to the right the x axle, upwards is the y axle,
(x
1, y
1) be the coordinate of telltale mark point DR image mid point under angle [alpha];
(X
3, Y
3) for telltale mark DR image mid point coordinate transform under angle beta comes, its coordinate system, take picture centre as initial point, is to the right the x axle, upwards is the y axle:
(X
1, Y
1) be the coordinate of telltale mark point DR image mid point under angle beta.
Step 500: obtain positional parameter, that is: obtain positional parameter according to coupling result of calculation and the definite tumor coordinate of described treatment plan.Detailed process is as follows: obtain this specifically labelled treatment coordinate (x, y, z).DDR image specifically labelled according to this, this specifically labelled treatment coordinate (x, y, z) is subtracted each other respectively with the three-dimensional coordinate of this specifically labelled DDR image, obtain the coordinate difference of the three-dimensional coordinate of this telltale mark treatment coordinate (x, y, z) and this specifically labelled DDR image, i.e. patient's positional parameter.
Step 600: location: tumor is reorientated according to described positional parameter.Detailed process is as follows: this positional parameter is increased on the corresponding coordinate of DDR image tumor coordinate, obtains the new treatment coordinate of tumor, with the treatment coordinate that tumor is new, tumor is reorientated.
In the preferred embodiment for the present invention, described telltale mark is a plurality of, and described a plurality of telltale marks are separately fixed at patient's diverse location with it, and 2 multiple the above telltale marks of DR image of taking do not overlap mutually in described shooting unit.Described matching unit 3 with a plurality of telltale marks respectively the specifically labelled coupling result of calculation corresponding with described DDR image average, get its average as final coupling result of calculation.Detailed process is as follows: if telltale mark is a plurality of, calculate respectively, obtained the treatment coordinate of this point by each telltale mark, then draw respectively specifically labelled coordinate difference separately, get the average of coordinate difference as positional parameter, then, described positioning unit 5 is increased to this positional parameter on the corresponding coordinate of DDR image tumor coordinate, obtain the new treatment coordinate of tumor, with the treatment coordinate that tumor is new, tumor is reorientated.Can obtain like this locating more accurately.
In the preferred embodiment for the present invention, in positioning step, also comprise the threshold values of reorientating target coordinate is set, by positional parameter and threshold values, reorientate target coordinate, when positional parameter is outside the threshold values scope, adjusts target position and reorientate target coordinate; When positional parameter is in the threshold values scope, with the positional parameter compensation, tumor is reorientated.
technique effect of the present invention is: build a kind of gamma radiation pendulum position demo plant and method, by the CT image reconstruction is obtained to contain specifically labelled DDR image, determine the oncotherapy coordinate according to the DDR image, described X-ray bulb and described image-forming assembly are arranged on respectively on described gamma radiation head and described arc track, described X-ray bulb and described image-forming assembly obtain at least two DR images to the imaging from different perspectives of patient tumors zone respectively in different angles, contain marking image in described DR image, described host computer generates the DDR image according to patient's CT image reconstruction, described host computer is the treatment coordinate according at least two DR images with specifically labelled Coordinate Conversion, then the coordinate that will treat the DDR framing labelling of coordinate and described corresponding angle mates calculating, and obtain positional parameter, described host computer is reorientated tumor according to positional parameter.The present invention's a kind of gamma radiation device pendulum position verification method and system, can make irradiation field tightly " follow " target area according to the variation adjustment treatment condition of organ site, accomplishes accurate treatment truly.
Above content is in conjunction with concrete preferred implementation further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For the general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, can also make some simple deduction or replace, all should be considered as belonging to protection scope of the present invention.
Claims (4)
1. a gamma radiation is put the position demo plant, it is characterized in that, comprise the gamma radiation head that gamma ray occurs, be arranged on the telltale mark that patient body-surface carries out tumor-localizing, send the X-ray bulb of imaging X-ray, the image-forming assembly that coordinates the imaging of described X-ray bulb, arc track, carry out the host computer of date processing, described gamma radiation head moves on described arc track, described X-ray bulb and described image-forming assembly are arranged on respectively on described gamma radiation head and described arc track, described X-ray bulb and described image-forming assembly obtain at least two DR images in different angles to the patient tumors regional imaging, contain marking image in described DR image, described host computer generates the DDR image according to patient's CT image reconstruction, described host computer is the treatment coordinate according at least two DR images with specifically labelled Coordinate Conversion, then the coordinate that will treat the DDR framing labelling of coordinate and corresponding angle mates calculating, and obtain positional parameter, described host computer is reorientated tumor according to positional parameter, described host computer comprises the matching unit that mates calculating, described matching unit with a plurality of telltale marks respectively the specifically labelled coupling result of calculation corresponding with described DDR image average, get its average as final coupling result of calculation.
2. gamma radiation is put the position demo plant according to claim 1, it is characterized in that, described image-forming assembly is flat panel detector.
3. gamma radiation is put the position demo plant according to claim 1, it is characterized in that, described host computer comprises the positioning unit of reorientating, and described positioning unit comprises the threshold value setting module that threshold value is set.
4. gamma radiation is put the position demo plant according to claim 1, it is characterized in that, described telltale mark is a plurality of, and described a plurality of telltale marks are separately fixed at patient's diverse location with it, at multiple the above telltale marks of DR image, do not overlap mutually.
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| CN102670237B (en) * | 2012-05-17 | 2014-12-10 | 西安一体医疗科技有限公司 | Gamma radiation positioning system |
| CN104203347B (en) * | 2013-02-28 | 2017-05-24 | 深圳市奥沃医学新技术发展有限公司 | Gamma knife heat treatment apparatus and gamma knife treatment system |
| CN108682011B (en) * | 2018-05-15 | 2021-07-16 | 齐鲁工业大学 | Sub-pixel-level real-time dynamic tumor image positioning and matching method |
| CN110368073A (en) * | 2019-05-21 | 2019-10-25 | 山东大学 | A kind of tumor-localizing method and system for tumor puncture |
| CN111031215A (en) * | 2019-12-25 | 2020-04-17 | 中创泰科(北京)科技有限公司 | Panoramic face snapshot camera and system |
| CN111603689B (en) * | 2020-05-22 | 2022-05-27 | 柯尼卡美能达再启医疗设备（上海）有限公司 | DR image guiding and positioning method and device |
| CN116782830A (en) * | 2020-12-28 | 2023-09-19 | 西安大医集团股份有限公司 | Method and device for determining arc starting and stopping angles for multi-target treatment and electronic equipment |
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