CN104217447B - A kind of method and medical imaging system for PET image reconstruction - Google Patents
A kind of method and medical imaging system for PET image reconstruction Download PDFInfo
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Abstract
The present invention provides a kind of method and medical imaging system for PET image reconstruction, main control computer sends out scan command, equipment control computer carries out data acquisition, and collected initial data is sent to and rebuilds computer and is stored in initial data memory module, event number will be met and be sent to meeting event history application module and be stored in database on main control computer；Then by dynamic reconstruction module, reads the event number that meets met in event database and generate history curve, load the raw data file in initial data memory module, generate initial data item；Initial data item is divided into different phase according to the rate of change of history curve, then each stage is divided into multiple frames, dynamic reconstruction is carried out to each frame.Family can be used more can intuitively see the situation of change for meeting event number for the present invention, so that some portion of data is obtained more careful clear reconstruction expression, so as to obtain more detailed, more microcosmic image information.
Description
Technical field
The present invention relates to medical imaging system more particularly to a kind of image rebuilding methods and its system for PET.
Background technology
Positron emission computed tomography (Positron Emission Tomography, PET) is widely answered
For field of medicaments, such as be commonly used in clinical medicine the diagnosis of cancer lesion, neuroscience field be commonly used for into
Row brain function identifies and brain function analysis, and also pries through effect with unique for pharmacology, drug effect in field of medicaments, because
This is also commonly used for the exploitation of auxiliary new drug.
PET is one kind using positron radionuclide as tracer, understands lesion function to the intake of tracer by lesions position
Metabolism state, and then the technology of diagnosis is made to disease.Specifically, the Radioactive decay events of tracer are positive electron hairs
It penetrates, the positive electron of transmitting generates that 511keV is gamma-ray to be met pair in bodily tissue and electron reaction, generally by PET scan
System will meet the gamma-rays detected in the time to being recorded as event, we referred to as meet event herein, multiple to meet event
Image of the number for rebuilding or creating scanned object, that is to say, that reconstruction image provides scanned object inner radiation
The information of Nuclear analysis.In current PET system, the data of scanning gained are usually directly reconstructed into images for user point
Analysis, however, the data information that a part is not meaningful is may included in such image reconstruction, in image reconstruction
Just the expression for making it possible to the part data of most worthy is weakened, and is possible to cause so certain subtle and important
Information is ignored.
To overcome drawbacks described above, a kind of allow user to be understood more intuitively to meet the variation shape of event it is necessory to provide
State selectively carries out the method and system of image reconstruction as needed.
Invention content
Problems solved by the invention is to provide a kind of method and medical imaging system for PET image reconstruction, makes user
The history curve for meeting event change more can be intuitively seen, to selectively make some portion of data obtain as needed
More careful clear reconstruction expression, to assist user preferably to be analyzed.
To solve the above problems, technical solution of the present invention provides a kind of method for PET image reconstruction, including：
Main control computer sends out scan command to equipment control computer, and equipment control computer carries out data acquisition；
Collected initial data is sent to reconstruction computer by equipment control computer, will be met event number and is sent to master
Meet event history application module on control computer, rebuild computer and initial data is stored in initial data memory module,
Meet event number and be stored in and meets event database；
Start dynamic reconstruction module, reads the event number that meets met in event database and generate history curve, load is former
Raw data file in beginning data memory module generates initial data item；According to the rate of change of history curve by original number
It is divided into different phase according to item, then each stage is divided into multiple frames, dynamic reconstruction is carried out to each frame.
Optionally, initial data item is made to be aligned by time of origin with history curve.
Optionally, initial data item is divided by way of dividing manual segmentation or automatically.
Optionally, selectable that initial data item is divided into several stages, and each stage is divided into several frames, then
Dynamic reconstruction is carried out to each frame.
Optionally, often change scheduled numerical value according to meeting event number, initial data item is automatically partitioned into a frame, so
Dynamic reconstruction is carried out to each frame afterwards.
The present invention also provides a kind of medical imaging system for PET, including main control computer, equipment control computer,
Rebuild computer, it is characterised in that：Further include meeting event history application module and dynamic reconstruction mould on the main control computer
Block, it includes initial data memory module to rebuild on computer.
Optionally, the dynamic reconstruction module, which may also be disposed on, rebuilds on computer.
Optionally, include original data division module in the dynamic reconstruction module.
Optionally, the raw data module includes manual segmentation module and automatic segmentation module.
Optionally, it can be loaded in dynamic reconstruction module and meet event number history curve.
Optionally, initial data item can be loaded in dynamic reconstruction module.
Further, initial data item is optionally divided into several frames.
Compared with prior art, the method for PET image reconstruction and imaging of medical system that technical solution of the present invention provides
System, using the history curve for meeting event in scanning process, user can selectively divide original number according to the variation of curve
Dynamic reconstruction is carried out according to this, so as to obtain more detailed, more microcosmic image information.
Description of the drawings
Fig. 1 is the method flow diagram that the present invention is used for PET image reconstruction；
Fig. 2 is medical imaging system schematic diagram of the present invention.
Fig. 3 is dynamic reconstruction module manual segmentation program interface schematic diagram of the present invention；
Fig. 4 is the automatic segmentation procedure interface schematic diagram of dynamic reconstruction module of the present invention；
Specific implementation mode
To make the above purposes, features and advantages of the invention more obvious and understandable, with reference to the accompanying drawings and examples
The specific implementation mode of the present invention is described in detail.Obviously, the embodiment described is only embodiment of the present invention
A part, rather than its whole.According to these embodiments, those skilled in the art are in the premise without creative work
Lower obtainable all other embodiment, belongs to protection scope of the present invention.
Embodiment one
Shown in Fig. 3, main process of the present embodiment for PET image reconstruction method is：
1. carrying out data acquisition, main control computer 1 sends out scan command to equipment control computer 2, and equipment control calculates
Machine 2 carries out data acquisition；
2. carrying out data transmission and storing, collected initial data is sent to reconstruction and calculated by equipment control computer 2
Machine 3, will meet event number and be sent on main control computer 1 and meet event history application module 11, and rebuilding computer 3 will be original
Data are stored in initial data memory module 31, meet event number and are stored in and meet event database 13；
3. carrying out image reconstruction, start dynamic reconstruction module 12, manual segmentation raw data module 121 is selected, such as Fig. 3 institutes
Show.There are a reference axis, the reference axis horizontal axis to represent acquisition time T, longitudinal axis generation in the manual segmentation raw data module 121
Table meets event number.It clicks to load and meets event history Curve Controls 1211, reading meets meeting in event database 13
Event number generates history song 4, clicks the initial data loaded in 1212 load initial data memory module 31 of initial data control
File generates initial data item 5, and the initial data item 5 is aligned with history curve 4 by initial time.Then user can basis
It shows the situation of change of history curve 4, determines initial data item being divided into several big stages, then NO.of Segments'
Stage numerical value needed for being inputted at input frame 1213 then inputs 3, system will if wished to be divided into 3 big stages in the present embodiment
Initial data item 5 is divided into three phases according to the change rate absolute value of history curve 4, it can be seen that in initial data item 5
Have an input label 1214 above each stage cut-off rule, user can according to oneself desirability to each regional imaging situation,
Input needs the frame number divided, system respective stage will to be divided into required frame according to the frame number of input in input label
Number, then to each frame carry out dynamic reconstruction (due to dynamic reconstruction process hereafter be currently available technology dynamic reconstruction mode,
Non-present invention content keypoint, therefore details are not described herein again).
Shown in referring to Figure 2 to Figure 4, the present invention is used for the medical imaging system of PET, includes mainly main control computer 1, equipment
Control computer 2 rebuilds computer 3 etc., further includes meeting event history application module 11 and dynamic on the main control computer 1
Module 12 is rebuild, the dynamic reconstruction module 12 may also set up on reconstruction computer 3.Rebuild on computer 3 includes original number
According to memory module 31.Include original data division module in the dynamic reconstruction module 12, the original data division module
Manual segmentation module 121 and automatic segmentation module 122 can be divided into.Each component function is described above, therefore herein no longer
It repeats.
Embodiment two
Referring to FIG. 1, FIG. 2 and FIG. 4 shown in, the present embodiment for PET for PET image reconstruction mode data acquire,
The all same of transmission and storage aspect and embodiment one, therefore details are not described herein again.Start dynamic reconstruction module 12, automatic point of selection
Raw data module 122 is cut, as shown in Figure 4.There are a reference axis, the coordinate in the automatic segmentation raw data module 122
Axis horizontal axis represents acquisition time T, and longitudinal axis representative meets event number.It clicks to load and meets event history Curve Controls 1221, read
The event number that meets met in event database 13 is taken to generate history song 4 ', click loading initial data control 1222 loads original
Raw data file in data memory module 31 generates initial data item 5 ', the initial data item 5 ' and history curve 4 '
It is aligned by initial time.Then user can be former in automatic segmentation in conjunction with actual needs according to the situation of change of history curve 4 '
A numerical value is inputted at the segmentation unit input frame 1223 of beginning data module 122, if the numerical value inputted in the present embodiment is 500, i.e.,
Expression system meets according to the situation of change for meeting event event number and often changes 500, the segmentation to initial data item 5 '
It will increase by a frame, dynamic reconstruction is carried out (since dynamic reconstruction process hereafter is existing at present to each frame after the completion of segmentation
The dynamic reconstruction mode of technology, non-present invention content keypoint, therefore details are not described herein again).
It should be noted that Fig. 3 of the present invention and Fig. 4 only schematically draw several main operational controls, it is intended merely to
The description to embodiment is assisted to illustrate, rather than for the limitation to the two operation interfaces in the present invention, people in the art
Member in the case where not needing creative work made by it is any change all belong to the scope of protection of the present invention.
Although the present invention is disclosed as above with preferred embodiment, it is not for limiting the present invention, any ability
Field technique personnel without departing from the spirit and scope of the present invention, may be by the methods and technical content of the disclosure above to this
Inventive technique scheme makes possible variation and modification, therefore, every content without departing from technical solution of the present invention, according to this hair
Bright technical spirit belongs to the technology of the present invention side to any simple modifications, equivalents, and modifications made by above example
The protection domain of case.
Claims (8)
1. a kind of method for PET image reconstruction, including：
Main control computer sends out scan command to equipment control computer, and equipment control computer carries out data acquisition；
Collected initial data is sent to reconstruction computer by equipment control computer, will be met event number and is sent to master control meter
Meet event history application module on calculation machine, rebuilds computer and initial data is stored in initial data memory module, meet
Event number, which is stored in, meets event database；
Start dynamic reconstruction module, bootload meets event history Curve Controls and meets meeting in event database to read
Event number generates history curve, and the history curve is the two-dimensional curve for meeting event number and changing over time；Bootload is former
Beginning data control generates initial data item, the initial data to load the raw data file in initial data memory module
Item is aligned with history curve by initial time；
Initial data item is divided into different phase according to the rate of change of history curve, then each stage is divided into multiple frames,
Dynamic reconstruction is carried out to each frame, or often changes scheduled numerical value according to event number is met, by the automatic Ground Split of initial data item
Go out a frame, dynamic reconstruction then is carried out to each frame.
2. the method according to claim 1 for PET image reconstruction, it is characterised in that：By manual segmentation or automatically
The mode of segmentation divides initial data item.
3. one kind being used for PET medical imaging systems, including main control computer, equipment control computer rebuilds computer, feature
It is：Further include meeting event history application module and dynamic reconstruction module on the main control computer, rebuilds on computer and wrap
Memory module containing initial data；The main control computer is used to send out scan command to equipment control computer；The equipment control
Computer processed is used to carry out data acquisition according to the order of main control computer, and collected initial data is sent to reconstruction meter
Calculation machine, will meet event number and is sent on main control computer and meet event history application module；The reconstruction computer is used for
Initial data is stored in initial data memory module, meets event number and is stored in and meet event database, and starts dynamic
Module is rebuild, bootload meets event history Curve Controls and gone through to read the event number generation that meets met in event database
History curve, the history curve are the two-dimensional curves for meeting event number and changing over time, bootload initial data control with
The raw data file in initial data memory module is loaded, initial data item, the initial data item and history curve are generated
It is aligned by initial time, initial data item is divided by different phase according to the rate of change of history curve, then each stage is divided
Multiple frames are cut into, dynamic reconstruction are carried out to each frame, or often change scheduled numerical value according to event number is met, by initial data item
It is automatically partitioned into a frame, dynamic reconstruction then is carried out to each frame.
4. medical imaging system according to claim 3, it is characterised in that：The dynamic reconstruction module may also be disposed on weight
It builds on computer.
5. medical imaging system according to claim 3, it is characterised in that：It include original number in the dynamic reconstruction module
According to segmentation module.
6. medical imaging system according to claim 5, it is characterised in that：The original data division module includes manual
Divide module and automatic segmentation module.
7. medical imaging system according to claim 3, it is characterised in that：It can be loaded in dynamic reconstruction module and meet thing
Number of packages history curve.
8. medical imaging system according to claim 3, it is characterised in that：Original number can be loaded in dynamic reconstruction module
According to item.
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| CN104657950B (en) * | 2015-02-16 | 2017-05-03 | 浙江大学 | Dynamic PET (positron emission tomography) image reconstruction method based on Poisson TV |
| CN105395209B (en) * | 2015-12-01 | 2018-10-02 | 沈阳东软医疗系统有限公司 | A kind of positron emission computerized tomography imaging system and method |
| WO2017140133A1 (en) * | 2016-02-18 | 2017-08-24 | Shanghai United Imaging Healthcare Co., Ltd. | System and method for medical imaging |
| US20170238882A1 (en) * | 2016-02-18 | 2017-08-24 | Shanghai United Imaging Healthcare Co., Ltd. | System and method for medical imaging |
| CN105761293B (en) * | 2016-03-17 | 2019-01-08 | 上海联影医疗科技有限公司 | Medical imaging procedure and system |
| CN107133549B (en) | 2016-02-29 | 2020-11-24 | 上海联影医疗科技有限公司 | ECT motion gating signal acquisition method and ECT image reconstruction method |
| US10282871B2 (en) * | 2017-07-10 | 2019-05-07 | Shanghai United Imaging Healthcare Co., Ltd. | Systems and methods for pet image reconstruction |
| CN107647877B (en) * | 2017-10-31 | 2020-05-19 | 鲁东大学 | Positron emission medical imaging system and imaging method |
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