CN104208131A - Method for preparing oral solution for preventing and treating carsickness - Google Patents
Method for preparing oral solution for preventing and treating carsickness Download PDFInfo
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- CN104208131A CN104208131A CN201410479569.0A CN201410479569A CN104208131A CN 104208131 A CN104208131 A CN 104208131A CN 201410479569 A CN201410479569 A CN 201410479569A CN 104208131 A CN104208131 A CN 104208131A
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Abstract
The invention relates to a method for preparing an oral solution for preventing and treating carsickness. The method comprises the following steps: weighing silene conoidea, white gourd kernel, wintercreeper, radix glycyrrhizae, himalayan willowweed herb, dominant pulicaria flower, gynostemma pentaphyllum, flos hibisci and eclipta alba, cleaning with water to remove impurities, drying in the air, mixing, grinding and screening by a 60-mesh screen, adding 5000ml of water, and soaking for 1 hour; taking the medicinal materials out; putting into a multifunctional extraction tank, adding water and decocting twice: in the first time, decocting 2 hours with water the amount of which is 10 times the amount of all the medicinal materials, taking decoction and filtering; and in the second time, decocting for 1.5 hours with water the amount of which is 8 times the amount of all the medicinal materials; mixing the two decoctions, filtering, and concentrating to obtain concentrate of which the relative density is 1.25 at 90 DEG C; refrigerating the concentrate for 24 hours at a low temperature of 4 DEG C, adding 5g of diatomite into the refrigerated liquid, filtering, and concentrating the filtrate until 1 milliliter contains 2.1g of crude drugs, uniformly stirring, refrigerating 24 hours at low temperature of 4 DEG C, filtering the refrigerated liquid to obtain the oral solution. The oral solution for preventing and treating carsickness is capable of effectively relieving the problem caused by carsickness and is remarkable in curative effect, and the focus can be effectively radically treated.
Description
Technical field
The present invention relates to automotive field, specifically, the present invention relates to a kind of preparation method of the oral liquid prevented and cure Car-sickness.
Background technology
Along with improving constantly of living standard, the continuous quickening of rhythm of life, people travel outdoors, going on business becomes the indispensable part of daily life.But but to having carsickness, the passenger of the motion sickness such as seasick, airsick brings the frightened and physiological reaction of psychology greatly.Its physiological reaction is embodied in: epigastric discomfort, pale complexion, be in a cold sweat, the motion sickness symptom such as dizzy, Nausea and vomiting.Cause the main cause of motion sickness symptom to be: due to the taken vehicles wave, jolt, rotate, accelerated motion etc., cause human body vestibulum auris internae statoreceptor unbalance.Traditional carsick medicine all contains Loratadine mostly, and after taking, the symptoms such as drowsiness, sleepy, tired can occur, it is larger to the side effect of health; And the drug effect of the external used medicine of car sickness therapeutic plaster is slow, the efficacy of a drug is little, DeGrain.
Summary of the invention
The object of the present invention is to provide a kind of preparation method of the oral liquid prevented and cure Car-sickness.
In order to realize object of the present invention, the invention provides a kind of preparation method of the oral liquid prevented and cure Car-sickness, the method can comprise the following steps:
Take the raw material of following weight portion: Herba Silenes conoideae 10-40 part, Semen Benincasae 20-80 part, Caulis Seu Folium Euonymi Fortunei 10-50 part, Radix Glycyrrhizae 10-40 part, Herba Epilobii Himalayensis 20-50 part, Pulicaria insignis Drumm. 1-30 part, Herb Gynostemmae Pentaphylli 10-40 part, one-tenth shrimp flower 10-30 part and Herba Ecliptae 1-30 part;
Above-mentioned raw materials is cleaned roguing, dries, mixing, pulverize 60 mesh sieves, added 5000 milliliters, soak 1h, pull medical material out to put during multi-functional extraction is filled with and decoct with water 2 times, first time adds up the water of medical material 10 times amount, decocts 2h, get decocting liquid, filter, second time adds up the water of medical material 8 times amount, decoct 1.5h, get twice decocting liquid to merge, filter, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.25; Described concentrated solution is placed in 4 DEG C of deepfreeze 24h, cold preservation liquid is added the kieselguhr of 5g, filter, filtrate reconcentration containing 2.1g crude drug amount to every milliliter, stirs, puts 4 DEG C of deepfreeze 24h, is filtered by cold preservation liquid, obtains oral liquid.
Preferably, method of the present invention takes the raw material of following weight portion: Herba Silenes conoideae 12 parts, Semen Benincasae 25 parts, Caulis Seu Folium Euonymi Fortunei 20 parts, 15 parts, Radix Glycyrrhizae, Herba Epilobii Himalayensis 25 parts, Pulicaria insignis Drumm. 9 parts, Herb Gynostemmae Pentaphylli 15 parts, one-tenth shrimp spend 20 parts and Herba Ecliptae 8 parts.
Preferably, method of the present invention takes the raw material of following weight portion: Herba Silenes conoideae 10 parts, Semen Benincasae 80 parts, Caulis Seu Folium Euonymi Fortunei 10 parts, 40 parts, Radix Glycyrrhizae, Herba Epilobii Himalayensis 20 parts, Pulicaria insignis Drumm. 30 parts, Herb Gynostemmae Pentaphylli 10 parts, one-tenth shrimp spend 10 parts and Herba Ecliptae 30 parts.
Preferably, method of the present invention takes the raw material of following weight portion: Herba Silenes conoideae 40 parts, Semen Benincasae 20 parts, Caulis Seu Folium Euonymi Fortunei 50 parts, 10 parts, Radix Glycyrrhizae, Herba Epilobii Himalayensis 50 parts, Pulicaria insignis Drumm. 1 part, Herb Gynostemmae Pentaphylli 40 parts, one-tenth shrimp spend 10 parts and Herba Ecliptae 30 parts.
Preferably, method of the present invention takes the raw material of following weight portion: Herba Silenes conoideae 20 parts, Semen Benincasae 60 parts, Caulis Seu Folium Euonymi Fortunei 40 parts, 35 parts, Radix Glycyrrhizae, Herba Epilobii Himalayensis 45 parts, Pulicaria insignis Drumm. 15 parts, Herb Gynostemmae Pentaphylli 25 parts, one-tenth shrimp spend 15 parts and Herba Ecliptae 25 parts.
Preferably, method of the present invention takes the raw material of following weight portion: Herba Silenes conoideae 35 parts, Semen Benincasae 50 parts, Caulis Seu Folium Euonymi Fortunei 30 parts, 15 parts, Radix Glycyrrhizae, Herba Epilobii Himalayensis 35 parts, Pulicaria insignis Drumm. 10 parts, Herb Gynostemmae Pentaphylli 20 parts, one-tenth shrimp spend 15 parts and Herba Ecliptae 15 parts.
In the present compositions, Herba Silenes conoideae is monarch drug, and Semen Benincasae and Caulis Seu Folium Euonymi Fortunei are ministerial drug; Herba Epilobii Himalayensis, Pulicaria insignis Drumm., Herb Gynostemmae Pentaphylli, one-tenth shrimp flower and Herba Ecliptae are adjuvant drug, and Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, for making medicine.
Advantage of the present invention adopts pure natural plant extract to be made, and has good drug efficacy, instant effect, persistent period long, easy to use, and have no side effect; Simultaneously the present invention is with low cost, it is simple to make, can large-scale promotion.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, various amendment or improvement can be made, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
Embodiment
Get Herba Silenes conoideae 12 grams, Semen Benincasae 25 grams, Caulis Seu Folium Euonymi Fortunei 20 grams, 15 grams, Radix Glycyrrhizae, Herba Epilobii Himalayensis 25 grams, Pulicaria insignis Drumm. 9 grams, Herb Gynostemmae Pentaphylli 15 grams, become shrimp to spend 20 grams and Herba Ecliptae 8 grams, clean roguing, dry, mixing, pulverize 60 mesh sieves, added 5000 milliliters, soak 1h, pull out medical material put multi-functional extraction fill with in decoct with water 2 times, add up the water of medical material 10 times amount for the first time, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 8 times amount, decocts 1.5h, gets twice decocting liquid and merges, filter, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.25; Described concentrated solution is placed in 4 DEG C of deepfreeze 24h, cold preservation liquid is added the kieselguhr of 5g, filter, filtrate reconcentration containing 2.1g crude drug amount to every milliliter, stirs, puts 4 DEG C of deepfreeze 24h, is filtered by cold preservation liquid, obtains oral liquid.
Experimental example
Physical data
With the range of driving of 40min, the 60 serious carsick patients of example, just can occur that serious dizzy vomiting is for standard.Be divided into two groups: treatment group 30 example, man 12 example, female 18 example; Minimum 12 years old of age, maximum 55 years old; Matched group 30 example, man 10 example, female 20 example; Minimum 13 years old of age, maximum 46 years old.Two groups of patients the age, sex side and no significant difference (P > 0.05).
Two groups of crowds, all after fully having a rest, ride when the mental status keeps good together.Close and point Hegu in matched group association oneself pressing, listen to the music simultaneously and distract attention.Treatment group is taking the oral liquid 10ml prepared in embodiment in first 2 hours by bus.
Observation index clinical symptoms: dizzy, vomiting.
Criterion of therapeutical effect
Effective: the symptoms such as dizzy vomiting are obviously improved; Effective: the diseases such as dizzy vomiting have certain improvement; Invalid: the symptoms such as dizzy vomiting are not improved.
Result
To the observation of vertigo symptoms
In matched group carsickness person, effective 8 examples, invalid 22 examples; The vertigo symptoms of 30 routine carsick persons for the treatment of group all disappears, and exchanges onboard, plays card normally, without any discomfort sense.
To the observation of symptoms of emesis
In matched group carsickness person, effective 6 examples, invalid 24 examples; 30 routine carsick persons for the treatment of group, all without any symptoms of emesis, drink water onboard, diet are all normal, without any discomfort sense.
Claims (6)
1. a preparation method for the oral liquid prevented and cure Car-sickness, is characterized in that, the method can comprise the following steps:
Take the raw material of following weight portion: Herba Silenes conoideae 10-40 part, Semen Benincasae 20-80 part, Caulis Seu Folium Euonymi Fortunei 10-50 part, Radix Glycyrrhizae 10-40 part, Herba Epilobii Himalayensis 20-50 part, Pulicaria insignis Drumm. 1-30 part, Herb Gynostemmae Pentaphylli 10-40 part, one-tenth shrimp flower 10-30 part and Herba Ecliptae 1-30 part;
Above-mentioned raw materials is cleaned roguing, dries, mixing, pulverize 60 mesh sieves, added 5000 milliliters, soak 1h, pull medical material out to put during multi-functional extraction is filled with and decoct with water 2 times, first time adds up the water of medical material 10 times amount, decocts 2h, get decocting liquid, filter, second time adds up the water of medical material 8 times amount, decoct 1.5h, get twice decocting liquid to merge, filter, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.25; Described concentrated solution is placed in 4 DEG C of deepfreeze 24h, cold preservation liquid is added the kieselguhr of 5g, filter, filtrate reconcentration containing 2.1g crude drug amount to every milliliter, stirs, puts 4 DEG C of deepfreeze 24h, is filtered by cold preservation liquid, obtains oral liquid.
2. preparation method according to claim 1, it is characterized in that, take the raw material of following weight portion: Herba Silenes conoideae 12 parts, Semen Benincasae 25 parts, Caulis Seu Folium Euonymi Fortunei 20 parts, 15 parts, Radix Glycyrrhizae, Herba Epilobii Himalayensis 25 parts, Pulicaria insignis Drumm. 9 parts, Herb Gynostemmae Pentaphylli 15 parts, one-tenth shrimp spend 20 parts and Herba Ecliptae 8 parts.
3. preparation method according to claim 1, it is characterized in that, take the raw material of following weight portion: Herba Silenes conoideae 10 parts, Semen Benincasae 80 parts, Caulis Seu Folium Euonymi Fortunei 10 parts, 40 parts, Radix Glycyrrhizae, Herba Epilobii Himalayensis 20 parts, Pulicaria insignis Drumm. 30 parts, Herb Gynostemmae Pentaphylli 10 parts, one-tenth shrimp spend 10 parts and Herba Ecliptae 30 parts.
4. preparation method according to claim 1, it is characterized in that, take the raw material of following weight portion: Herba Silenes conoideae 40 parts, Semen Benincasae 20 parts, Caulis Seu Folium Euonymi Fortunei 50 parts, 10 parts, Radix Glycyrrhizae, Herba Epilobii Himalayensis 50 parts, Pulicaria insignis Drumm. 1 part, Herb Gynostemmae Pentaphylli 40 parts, one-tenth shrimp spend 10 parts and Herba Ecliptae 30 parts.
5. preparation method according to claim 1, it is characterized in that, take the raw material of following weight portion: Herba Silenes conoideae 20 parts, Semen Benincasae 60 parts, Caulis Seu Folium Euonymi Fortunei 40 parts, 35 parts, Radix Glycyrrhizae, Herba Epilobii Himalayensis 45 parts, Pulicaria insignis Drumm. 15 parts, Herb Gynostemmae Pentaphylli 25 parts, one-tenth shrimp spend 15 parts and Herba Ecliptae 25 parts.
6. preparation method according to claim 1, it is characterized in that, take the raw material of following weight portion: Herba Silenes conoideae 35 parts, Semen Benincasae 50 parts, Caulis Seu Folium Euonymi Fortunei 30 parts, 15 parts, Radix Glycyrrhizae, Herba Epilobii Himalayensis 35 parts, Pulicaria insignis Drumm. 10 parts, Herb Gynostemmae Pentaphylli 20 parts, one-tenth shrimp spend 15 parts and Herba Ecliptae 15 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410479569.0A CN104208131A (en) | 2014-09-18 | 2014-09-18 | Method for preparing oral solution for preventing and treating carsickness |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410479569.0A CN104208131A (en) | 2014-09-18 | 2014-09-18 | Method for preparing oral solution for preventing and treating carsickness |
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| CN104208131A true CN104208131A (en) | 2014-12-17 |
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| CN201410479569.0A Pending CN104208131A (en) | 2014-09-18 | 2014-09-18 | Method for preparing oral solution for preventing and treating carsickness |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1080671A1 (en) * | 1999-09-03 | 2001-03-07 | Toyo Tire & Rubber Co., Ltd . | Seat cushion pad |
| CN101112471A (en) * | 2007-08-29 | 2008-01-30 | 北京艺信堂医药研究所 | Chinese traditional medicine preparations for treating pregnancy vertigo |
| CN103405738A (en) * | 2013-08-22 | 2013-11-27 | 张素平 | Pharmaceutical composition for treating chronic cholecystitis |
-
2014
- 2014-09-18 CN CN201410479569.0A patent/CN104208131A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1080671A1 (en) * | 1999-09-03 | 2001-03-07 | Toyo Tire & Rubber Co., Ltd . | Seat cushion pad |
| CN101112471A (en) * | 2007-08-29 | 2008-01-30 | 北京艺信堂医药研究所 | Chinese traditional medicine preparations for treating pregnancy vertigo |
| CN103405738A (en) * | 2013-08-22 | 2013-11-27 | 张素平 | Pharmaceutical composition for treating chronic cholecystitis |
Non-Patent Citations (2)
| Title |
|---|
| 荣加和: "清热除湿法治疗眩晕", 《四川中医》 * |
| 蒲昭: "含服"速效救心丸"可防治晕车", 《农家科技》 * |
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Application publication date: 20141217 |