CN104189694B - A kind of Chinese medicine composition containing Fructus Alpiniae Oxyphyllae and Fructus Lycii and preparation method thereof - Google Patents
A kind of Chinese medicine composition containing Fructus Alpiniae Oxyphyllae and Fructus Lycii and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to field of health care food, be specifically related to a kind of Chinese medicine composition containing Fructus Alpiniae Oxyphyllae and Fructus Lycii.Said composition also comprises white sugar, glucose, Mel, Concha Ostreae; This Chinese medicine composition can be made into granule, syrup or capsule; It has strong kidney and to dispel fire, soothing the liver refreshment, removing mass dredging collateral, and QI invigorating righting, makes eliminating evil just wound, helps just with eliminating evil effect, can be used as daily health products, can also to get rid of in body the heavy metals such as lead, hydrargyrum, be particularly useful for Children with Hyperkinetic Syndrome.
Description
Technical field
The invention belongs to field of health care products, be specifically related to a kind of Chinese medicine composition containing Fructus Alpiniae Oxyphyllae and Fructus Lycii.
Background technology
At present, because stress is excessive, the reasons such as dietary habit is not good, and work and rest irregular, quantity of motion is little, amblent air temperature deterioration, cause more and more people to be in slight deficiency of kidney yin, the sub-health state of excess of liver-YANG.
The deficiency of kidney yin of some severe, excess of liver-YANG cause a class crowd with obvious condition symptoms, and that is exactly Children with Hyperkinetic Syndrome.Childhood hyperkinetic syndrome mainly refers to " intelligence close to normal, can not concentrate, emotional instability, and have consciousness and cognitive disorder, a kind of syndrome with central nervous system disorders by attention ", and this disease is the disease of motion, thinking, feelings will, spirit.Special send out in childhood period, it and child are still in continuous growth, growth and constantly improve the body and mind feature in stage closely related.Infant hyperactivity, mainly deficiency of kidney yin, caused by excess of liver-YANG." the large opinion of Plain Questions YIN YANG classification of natural phenomena " says " the kidney generating marrow and dominating bone " that the prosperity and decline of essence in kidney not only affects the g and D of bone, and the full and growth of impact and spinal cord and brains, spinal cord leads in brain, and marrow is poly-forms brain, therefore claims brain to be " brain ".Essence in kidney fills, then brain must be supported, and the growth of brain is just sound, just can give full play to the physiological function of its " house of intelligence ", otherwise essence in kidney is not enough, then brain is lost and supported, and forms the pathological change of deficiency of marrow-reservoir.
In prior art, Fructus Alpiniae Oxyphyllae, Fructus Lycii achieve certain achievement in balance system, balanced conditioning health.As CN102697137A discloses a kind of Chinese yam-medlar drink, by the Chinese herbal medicine of following parts by weight through mixing immersion, decocting, extraction medicinal liquid and obtaining: Rhizoma Dioscoreae 20 ~ 30 parts, Fructus Lycii 15 ~ 20 parts, Semen Ziziphi Spinosae 10 ~ 20 parts, Fructus Alpiniae Oxyphyllae 10 ~ 20 parts, Bulbus Lilii 10 ~ 15 parts, Radix Ophiopogonis 10 ~ 15 parts, Semen Euryales 10 ~ 15 parts, Rhizoma Polygonati 15 ~ 20 parts, Radix Puerariae 10 ~ 15 parts, Fructus Mori 10 ~ 15 parts, Fructus Crataegi 10 ~ 15 parts, 10 ~ 15 parts, Radix Glycyrrhizae.To be general population be used for promoting the production of body fluid to quench thirst as a kind of beverage to this beverage, invigorating spleen and reinforcing stomach can be played again, profit nourishes heart lung, nourishing the liver and kidney, anti-ageing brain-strengthening, building body, raising immunity and human activity, containment " subhealth state " sports health-care effect.And for example CN103495096A has opened a kind of Fructus Alpiniae Oxyphyllae of warming spleen and tonifying kidney, is be made up of the raw material of following weight parts: Fructus Alpiniae Oxyphyllae 180-200, Flos Longan 1-2, Fructus Mori 2-3, Fructus Lycii 1-2, Folium Malloti Apeltae 1-2, Fructus Amomi 2-3, Cortex cinnamomi japonici (Ramulus Cinnamomi) 2-3, Cortex Melaleucae leucadendrae skin 1-2, Flos Granati 1-2, applejack 5-6, wheatfeed are appropriate; Brew that drink can invigorating spleen and kidney for a long time.
Effect of Fructus Alpiniae Oxyphyllae, Fructus Lycii is used, and add other prescriptions all, developing the health product can nursing one's health " deficiency of kidney yin, excess of liver-YANG " person's health, realize that effect is more stable, toxic and side effects is little, crowd is subject to simultaneously, is a development activities needing to pay creative work.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition containing Fructus Alpiniae Oxyphyllae and Fructus Lycii, said composition has fiery spleen invigorating of dispelling, the health-care effect of nourish yin and calm the liver, gentle circulation of qi promoting.
The invention provides a kind of Chinese medicine composition containing Fructus Alpiniae Oxyphyllae and Fructus Lycii, comprise following each component: white sugar, glucose, Mel, Concha Ostreae, Fructus Lycii, Fructus Alpiniae Oxyphyllae.
Mel is sweet, flat, returns lung, spleen, large intestine channel.Energy invigorating middle warmer, moisturizes, pain relieving, removing toxic substances.Concha Ostreae is feeble QI, and taste is micro-salty.Nature and flavor are salty, are slightly cold.Return liver, gallbladder, kidney channel.Energy tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.Fructus Lycii: sweet in the mouth, property is put down.Chinese medicine think its can tonifying liver the moon, nourishing the liver blood, replenishing vital essence to improve eyesight.Modern pharmacological research proves: Fructus Lycii can promote that hepatocyte is newborn.Fructus Alpiniae Oxyphyllae has special fragrance, acrid in the mouth, micro-hardship.Nature and flavor are pungent, temperature.Return spleen, kidney channel.Can warming the kidney controlling nocturnal emission with astringent drugs reducing urination, warming spleen and stopping diarrhaly take the photograph saliva.Rush down for kidney deficiency, spleen diarrhea due to cold pathogen, abdomen is cold, the many salivas of mouth.Above-mentioned all medicines share, effect of energy nourishing YIN and clearing away fire, suppressing the hyperactive liver and subsiding YANG, invigorating middle warmer spleen invigorating.
The Chinese medicine composition that the invention provides containing Fructus Alpiniae Oxyphyllae and Fructus Lycii also comprises following each component: Folium Ginseng, Fructus Corni, Rhizoma Acori Graminei, Fructus Ligustri Lucidi, Concretio Silicea Bambusae, Radix Polygalae.
Folium Ginseng gas delicate fragrance, mildly bitter flavor and sweet, nature and flavor are bitter, sweet, cold.Attach to the lung and stomach meridians.Energy using tonifying Qi reinforcing lungs, drives away summer heat and promotes the production of body fluid, and for qi-asthenia cough, summer-heat is irritated, and Tianjin wound is thirsty, and the head is unclear, and extremity are tired weary.Fructus Corni feeble QI, sour in the mouth, puckery, micro-hardship.Nature and flavor are sour, puckery, tepor.Return liver, kidney channel energy liver and kidney tonifying, arresting collape syndrome by astringents.Fructus Ligustri Lucidi feeble QI, sweet in the mouth, micro-bitterness.For the poor vision of the hepatic and renal YIN deficiency, visual deterioration, early whitening of beard and hair, soreness of waist tinnitus and fever due to yin deficiency etc.This product energy invigorating the liver and kidney deficiency of YIN, but the efficacy of a drug is gentle, slowly must get effect.Rhizoma Acori Graminei is nature and flavor sweet, bitter, cold.Return liver, kidney channel.Can nourishing the liver and kidney, for the hepatic and renal YIN deficiency, dizzy ear toot, soreness of the waist and knees, beard and hair drought is white, and poor vision, interior-heat is quenched one's thirst, osteopyrexia and fever.Concretio Silicea Bambusae is feeble QI, and lightly seasoned, nature and flavor are sweet, cold, GUIXIN, Liver Channel, energy clear heat and eliminate phlegm, cool heart arresting convulsion.For calentura coma, middle wind-phlegm fan, the hot infantile convulsion of children's's expectorant, tic, night cry.Radix Polygalae is that nature and flavor are bitter, pungent, temperature.GUIXIN, kidney, lung meridian.Can calm the nerves Fructus Alpiniae Oxyphyllae, restoring normal coordination between the heart and kidney, eliminates the phlegm, detumescence.The insomnia and dreamful sleep caused for disarmony between the heart and kidney, forgetful palpitation with fear, staring spells, expectoration is not well.Make the adding of above-mentioned all medicines containing the Chinese medicine composition prescription nourishing YIN and clearing away fire of Fructus Alpiniae Oxyphyllae and Fructus Lycii, suppressing the hyperactive liver and subsiding YANG, invigorating middle warmer spleen invigorating, soothing the liver refreshment, using tonifying Qi reinforcing lungs, the effect of promoting the production of body fluid of driving away summer heat better.
The invention provides the Chinese medicine composition preferred version containing Fructus Alpiniae Oxyphyllae and Fructus Lycii of above-mentioned formula, according to weight parts, comprise following each component: Folium Ginseng 3-5 part, Fructus Corni 10-12 part, Rhizoma Acori Graminei 6-9 part, Fructus Ligustri Lucidi 6-9 part, Concretio Silicea Bambusae 2-5 part, Radix Polygalae 5-7 part.This prescription nourishing YIN and clearing away fire, suppressing the hyperactive liver and subsiding YANG, invigorating middle warmer spleen invigorating, using tonifying Qi reinforcing lungs, drive away summer heat promote the production of body fluid effect more remarkable.
Chinese medicine composition containing Fructus Alpiniae Oxyphyllae and Fructus Lycii provided by the invention also can be made into granule, syrup or capsule.
Present invention also offers the above-mentioned preparation method containing the Chinese medicine composition of Fructus Alpiniae Oxyphyllae and Fructus Lycii, step is as follows: by recipe quantity, except white sugar, glucose, other each material outside Mel adds the 3-8 water doubly of medical material gross weight respectively, soak 30-60 minute, decoct 2-3 time, each 0.5-3 hour, filter, merge all filtrate, add white sugar and glucose is mixed well, to be this relative density of 1.1-1.3(be at 60 c testing result that concentrating under reduced pressure is relative density) extractum, call in Mel, then granule is made according to prior art, syrup or capsule.
In embodiment, the percentage by weight of each composition finally obtains through repeatedly allocating, not only mouthfeel is easy to accept, and the blend proportion balanced and reasonable of each composition, the effective effect playing each composition, especially after Concha Ostreae, Fructus Lycii, Fructus Alpiniae Oxyphyllae being combined, the property of medicine matches each other and promotes, greatly improve effect of soothing liver-QI refreshment, Bushen Tongluo, fiery QI invigorating of dispelling, through most experiments digital proof, the summation of its effect that can reach after adopting three kinds of compositions respectively comparatively separately improves more than 1.5 times.Table 1 result also show, and compared with matched group, the Chinese medicine composition containing Fructus Alpiniae Oxyphyllae and Fructus Lycii of the present invention has significant therapeutic effect, and after adding Folium Ginseng, Fructus Corni, Rhizoma Acori Graminei, Fructus Ligustri Lucidi, Concretio Silicea Bambusae, Radix Polygalae in prescription, therapeutic effect is more excellent.
Chinese medicine composition containing Fructus Alpiniae Oxyphyllae and Fructus Lycii provided by the present invention has nourishing YIN and clearing away fire, suppressing the hyperactive liver and subsiding YANG, soothing the liver refreshment, invigorating middle warmer spleen invigorating, using tonifying Qi reinforcing lungs, drive away summer heat promote the production of body fluid, QI invigorating righting, make eliminating evil just wound, help just with eliminating evil effect, effect is more stable, toxic and side effects is little, crowd is subject to, can be used as daily health products, especially the health product of Children with Hyperkinetic Syndrome.Even if also injury can not be formed to human body in a large amount of edible situation, can be used as daily health products and eat for a long time.
The Chinese medicine composition containing Fructus Alpiniae Oxyphyllae and Fructus Lycii provided by the present invention, exactly because effect of nourishing YIN and clearing away fire, suppressing the hyperactive liver and subsiding YANG can be had, so internal organs of the body function can be increased, especially acceleration bodies inner blood circulation, improve excretory function, especially diuresis function, thus the heavy metals such as body interior lead, hydrargyrum can also be got rid of.Achieve unforeseeable technique effect.
Detailed description of the invention
Further describe the present invention below by way of detailed description of the invention, but the present invention is not limited only to following examples.
embodiment 1
Prescription:: white sugar 0.5kg, glucose 1kg, Mel 1kg, Concha Ostreae 7kg, Fructus Lycii 12kg, Fructus Alpiniae Oxyphyllae 15kg.
Step is as follows: by recipe quantity, other each material except white sugar, glucose, Mel adds the water of medical material gross weight 8 times respectively, soak 30 minutes, decoct 3 times, each 0.5 hour, filter, merge all filtrate, add white sugar and glucose is mixed well, concentrating under reduced pressure becomes relative density to be this relative density of 1.3(to be testing result at 60 c) extractum, call in Mel, then, vacuum drying, receive dry cream to moisture < 5.0%, pulverize, cross 60 mesh sieves, obtain fine powder.Mix with dextrin, 95% ethanol, dry granulation, with 12 orders, 40 mesh sieve granulate, make granule.
embodiment 2
Prescription: white sugar 0.9kg, glucose 0.5kg, Mel 1.2kg, Concha Ostreae 8kg, Fructus Lycii 9kg, Fructus Alpiniae Oxyphyllae 15kg.
Folium Ginseng 3kg, Fructus Corni 12kg, Rhizoma Acori Graminei 6kg, Fructus Ligustri Lucidi 9kg, Concretio Silicea Bambusae 5kg, Radix Polygalae 5kg.
Preparation process is as follows: by recipe quantity, other each material except white sugar, glucose, Mel adds the water of 6 times of medical material gross weight respectively, soak 60 minutes, decoct 2 times, each 3 hours, filter, merge all filtrate, add white sugar and glucose is mixed well, be evaporated to the extractum (this relative density is testing result at 60 c) of relative density 1.1, call in Mel, then, vacuum drying, receive dry cream to moisture < 5.0%, pulverize, cross 60 mesh sieves, obtain fine powder.Mix with dextrin, 95% ethanol, dry granulation, with 12 orders, 40 mesh sieve granulate, make granule.
embodiment 3
Prescription: white sugar 0.7kg, glucose 0.7kg, Mel 0.9kg, Concha Ostreae 8kg, Fructus Lycii 10kg, Fructus Alpiniae Oxyphyllae 12kg,
Folium Ginseng 5kg, Fructus Corni 10kg, Rhizoma Acori Graminei 7kg, Fructus Ligustri Lucidi 7kg, Concretio Silicea Bambusae 3kg, Radix Polygalae 7kg.
Preparation process is as follows: by recipe quantity, other each material except white sugar, glucose, Mel adds the water of 5 times of medical material gross weight respectively, soak 30 minutes, decoct 3 times, each 1 hour, filter, merge all filtrate, add white sugar and glucose is mixed well, concentrating under reduced pressure becomes relative density to be this relative density of 1.2(to be testing result at 60 c) extractum, call in Mel, then, vacuum drying, receive dry cream to moisture < 5.0%, pulverize, cross 60 mesh sieves, obtain fine powder.Mix with dextrin, 95% ethanol, dry granulation, with 12 orders, 40 mesh sieve granulate, make granule.
embodiment 4
Prescription: white sugar 0.7kg, glucose 0.7kg, Mel 0.9kg, Concha Ostreae 8kg, Fructus Lycii 10kg, Fructus Alpiniae Oxyphyllae 12kg,
Folium Ginseng 5kg, Fructus Corni 10kg, Rhizoma Acori Graminei 7kg, Fructus Ligustri Lucidi 7kg, Concretio Silicea Bambusae 3kg, Radix Polygalae 7kg.
Preparation process is as follows: by recipe quantity, other each material except white sugar, glucose, Mel adds the water of 8 times of medical material gross weight respectively, soaks 60 minutes, decoct 3 times, each 0.5 hour, filter, merge all filtrate, add white sugar and glucose is mixed well, be evaporated to the extractum (this relative density is testing result at 60 c) of relative density 1.02, call in Mel, add sodium benzoate, with distilled water diluting to 1L, subpackage, sterilizing, obtains syrup.
embodiment 5
Prescription: white sugar 0.6kg, glucose 0.9kg, Mel 1kg, Concha Ostreae 9kg, Fructus Lycii 10kg, Fructus Alpiniae Oxyphyllae 12kg,
Folium Ginseng 5kg, Fructus Corni 10kg, Rhizoma Acori Graminei 6kg, Fructus Ligustri Lucidi 7kg, Concretio Silicea Bambusae 5kg, Radix Polygalae 5kg.
Preparation process is as follows: by recipe quantity, other each material except white sugar, glucose, Mel adds the water of 5 times of medical material gross weight respectively, soaks 30 minutes, decoct 3 times, each 1 hour, filter, merge all filtrate, add white sugar and glucose is mixed well, be evaporated to the extractum (this relative density is testing result at 60 c) of relative density 1.06, call in Mel, add sodium benzoate, with distilled water diluting to 1L, subpackage, sterilizing, obtains syrup.
embodiment 6
Prescription: white sugar 0.7kg, glucose 1kg, Mel 0.7kg, Concha Ostreae 7kg, Fructus Lycii 12kg, Fructus Alpiniae Oxyphyllae 12kg,
Folium Ginseng 3kg, Fructus Corni 12kg, Rhizoma Acori Graminei 9kg, Fructus Ligustri Lucidi 9kg, Concretio Silicea Bambusae 5kg, Radix Polygalae 7kg.
Step is as follows: by recipe quantity, other each material except white sugar, glucose, Mel adds the water of 3 times of medical material gross weight respectively, soaks 30 minutes, decoct 3 times, each 1 hour, filter, merge all filtrate, add white sugar and glucose is mixed well, be evaporated to the extractum (this relative density is testing result at 60 c) of relative density 1.2, call in Mel, then, vacuum drying, receive dry cream to moisture < 5.0%, pulverize, cross 60 mesh sieves, obtain fine powder; Mix with starch, 95% ethanol, dry granulation, cross 60 mesh sieves, encapsulated and get final product.
the impact on hyperkinetic syndrome infant of drug effect checking embodiment Chinese medicine composition of the present invention
samples selection:
5-15 year, hyperkinetic syndrome infant, totally 60, man 39, female 21, random packet.
administration
Matched group: placebo: starch, white sugar are granulated, and oral, three times on the one, each 1g, is used in conjunction 3 months.
Treatment group 1: embodiment 1 gained granule, oral, three times on the one, each 1g, is used in conjunction 3 months.
Treatment group 2: embodiment 3 gained granule, oral, three times on the one, each 1g, is used in conjunction 3 months.
effect category
Remarkable result: main clinic symptoms is obviously improved, social adaptation recovers substantially, and school grade improves.
Effective: main clinic symptoms disappears substantially, school grade is improved, but stable not.
Invalid: main clinic symptoms is unchanged or increase the weight of, and school grade is not improved.
Table 1 comparitive study
Table 1 result shows, and treatment group has significant therapeutic effect compared with matched group, and treatment group 2 is more due to treatment group 1.
Claims (3)
1. one kind contains the Chinese medicine composition of Fructus Alpiniae Oxyphyllae and Fructus Lycii, it is characterized in that, according to weight parts, it is by following each component: white sugar 0.5-0.9 part, glucose 0.5-1 part, Mel 0.7-1.2 part, Concha Ostreae 7-9 part, Fructus Lycii 9-12 part, Fructus Alpiniae Oxyphyllae 12-15 part, Folium Ginseng 3-5 part, Fructus Corni 10-12 part, Rhizoma Acori Graminei 6-9 part, Fructus Ligustri Lucidi 6-9 part, Concretio Silicea Bambusae 2-5 part, Radix Polygalae 5-7 part are made.
2. the Chinese medicine composition containing Fructus Alpiniae Oxyphyllae and Fructus Lycii as claimed in claim 1, it is characterized in that, this Chinese medicine composition makes granule, syrup or capsule.
3. one kind contains the preparation method of the Chinese medicine composition of Fructus Alpiniae Oxyphyllae and Fructus Lycii as claimed in claim 1, it is characterized in that, step is as follows: by recipe quantity, other each material except white sugar, glucose, Mel adds the 3-8 water doubly of medical material gross weight respectively, soak 30-60 minute, decoct 2-3 time, each 0.5-3 hour, filter, merge all filtrate, add white sugar and glucose is mixed well, concentrating under reduced pressure becomes relative density to be the extractum of 1.1-1.3, call in Mel, then make granule, syrup or capsule.
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CN1156031A (en) * | 1995-12-04 | 1997-08-06 | 南京臣功制药有限公司 | Oral medicine for dropping blood lead and its preparing method |
CN101011521A (en) * | 2006-01-26 | 2007-08-08 | 烟台大洋制药有限公司 | Chinese patent drug for nourishing liver and kidney, tranquilizing the mind and developing intelegence and its preparation method |
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CN1156031A (en) * | 1995-12-04 | 1997-08-06 | 南京臣功制药有限公司 | Oral medicine for dropping blood lead and its preparing method |
CN101011521A (en) * | 2006-01-26 | 2007-08-08 | 烟台大洋制药有限公司 | Chinese patent drug for nourishing liver and kidney, tranquilizing the mind and developing intelegence and its preparation method |
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Effective date of registration: 20180802 Address after: 410205 No. 901-907, A building, International Industrial Park incubator, 229 Luxi Road, Changsha high tech Zone, Hunan, China. Patentee after: HUNAN ZHIDA MEDICAL TECHNOLOGY CO., LTD. Address before: 410205 No. 901-907, A building, International Industrial Park incubator, 229 Luxi Road, Tongzi high tech Development Zone, Changsha, Hunan Patentee before: Bian Guoliang |