CN104204768B - 分选流式细胞仪 - Google Patents

分选流式细胞仪 Download PDF

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Publication number
CN104204768B
CN104204768B CN201380018973.1A CN201380018973A CN104204768B CN 104204768 B CN104204768 B CN 104204768B CN 201380018973 A CN201380018973 A CN 201380018973A CN 104204768 B CN104204768 B CN 104204768B
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China
Prior art keywords
sorting
drop
charge
fluid
droplet
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Chinese (zh)
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CN104204768A (zh
Inventor
托马斯·L·思拉舍
布鲁斯·G·贝利
埃里克·冯·塞根
杰夫瑞·W·戴杰尔
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Beckman Coulter Inc
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Beckman Instruments Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G01N15/1492—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties within droplets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1021—Measuring mass of individual particles

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  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electrostatic Separation (AREA)
CN201380018973.1A 2012-02-09 2013-02-08 分选流式细胞仪 Active CN104204768B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261597022P 2012-02-09 2012-02-09
US61/597,022 2012-02-09
PCT/US2013/025308 WO2013119924A1 (en) 2012-02-09 2013-02-08 Sorting flow cytometer

Publications (2)

Publication Number Publication Date
CN104204768A CN104204768A (zh) 2014-12-10
CN104204768B true CN104204768B (zh) 2018-07-10

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CN201380018973.1A Active CN104204768B (zh) 2012-02-09 2013-02-08 分选流式细胞仪

Country Status (9)

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US (1) US10190959B2 (enExample)
EP (1) EP2812671B1 (enExample)
JP (1) JP6192665B2 (enExample)
CN (1) CN104204768B (enExample)
AU (1) AU2013216878B2 (enExample)
ES (1) ES2776157T3 (enExample)
IN (1) IN2014DN06692A (enExample)
SG (1) SG11201404780VA (enExample)
WO (1) WO2013119924A1 (enExample)

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CN109916803A (zh) * 2019-02-27 2019-06-21 苏州朗如精密机械科技有限公司 一种流式细胞分析仪样本分选检测模块及其全自动分选检测方法
EP3956649A4 (en) 2019-04-19 2023-01-04 Becton, Dickinson and Company Subsampling flow cytometric event data
CN112730408B (zh) * 2020-12-24 2024-07-09 贝克曼库尔特生物科技（苏州）有限公司 液流检测系统和液流检测方法以及分选装置
CN115824736B (zh) * 2022-11-10 2023-10-20 东西分析仪器(天津)有限公司 一种微量样品点样头
CN115962995B (zh) * 2022-12-26 2023-07-04 中国科学院基础医学与肿瘤研究所(筹) 一种全自动微生物染色制片装置

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Also Published As

Publication number Publication date
AU2013216878A1 (en) 2014-08-28
ES2776157T3 (es) 2020-07-29
IN2014DN06692A (enExample) 2015-05-22
US10190959B2 (en) 2019-01-29
EP2812671A1 (en) 2014-12-17
JP6192665B2 (ja) 2017-09-06
JP2015507204A (ja) 2015-03-05
CN104204768A (zh) 2014-12-10
US20150050688A1 (en) 2015-02-19
EP2812671B1 (en) 2019-12-25
SG11201404780VA (en) 2014-09-26
AU2013216878B2 (en) 2016-09-29
WO2013119924A1 (en) 2013-08-15

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