AU2013216878B2 - Sorting flow cytometer - Google Patents

Sorting flow cytometer Download PDF

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Publication number
AU2013216878B2
AU2013216878B2 AU2013216878A AU2013216878A AU2013216878B2 AU 2013216878 B2 AU2013216878 B2 AU 2013216878B2 AU 2013216878 A AU2013216878 A AU 2013216878A AU 2013216878 A AU2013216878 A AU 2013216878A AU 2013216878 B2 AU2013216878 B2 AU 2013216878B2
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AU
Australia
Prior art keywords
drop
charge
particle
fluid stream
sort
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AU2013216878A
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English (en)
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AU2013216878A1 (en
Inventor
Bruce G. Bailey
Jeffrey W. Degeal
Thomas L. Thrasher
Eric VON SEGGERN
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Beckman Coulter Inc
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Beckman Coulter Inc
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Publication of AU2013216878A1 publication Critical patent/AU2013216878A1/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G01N15/1492—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties within droplets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1021—Measuring mass of individual particles

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  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electrostatic Separation (AREA)
AU2013216878A 2012-02-09 2013-02-08 Sorting flow cytometer Active AU2013216878B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261597022P 2012-02-09 2012-02-09
US61/597,022 2012-02-09
PCT/US2013/025308 WO2013119924A1 (en) 2012-02-09 2013-02-08 Sorting flow cytometer

Publications (2)

Publication Number Publication Date
AU2013216878A1 AU2013216878A1 (en) 2014-08-28
AU2013216878B2 true AU2013216878B2 (en) 2016-09-29

Family

ID=47750827

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013216878A Active AU2013216878B2 (en) 2012-02-09 2013-02-08 Sorting flow cytometer

Country Status (9)

Country Link
US (1) US10190959B2 (enExample)
EP (1) EP2812671B1 (enExample)
JP (1) JP6192665B2 (enExample)
CN (1) CN104204768B (enExample)
AU (1) AU2013216878B2 (enExample)
ES (1) ES2776157T3 (enExample)
IN (1) IN2014DN06692A (enExample)
SG (1) SG11201404780VA (enExample)
WO (1) WO2013119924A1 (enExample)

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JP6447506B2 (ja) * 2013-10-16 2019-01-09 ソニー株式会社 粒子分取装置及び粒子分取方法
JP6136843B2 (ja) * 2013-10-17 2017-05-31 ソニー株式会社 粒子分取装置、粒子分取方法及びプログラム
US20150160246A1 (en) 2013-12-11 2015-06-11 Analiza, Inc. Devices and methods for determining and/or isolating cells such as circulating cancer or fetal cells
US9709556B2 (en) 2013-12-11 2017-07-18 Analiza, Inc. Devices and methods for determining and/or isolating circulating cancer cells
USD787701S1 (en) * 2014-03-21 2017-05-23 Intellicyt Corporation Flow cytometer system shelf unit
JP2016080563A (ja) * 2014-10-20 2016-05-16 日本光電工業株式会社 分析システム、分析装置
US10091279B2 (en) 2015-05-27 2018-10-02 FlowJo, LLC Wireless connected laboratory
US11254557B2 (en) 2016-05-17 2022-02-22 Sony Corporation Particle extraction apparatus and particle extraction method
US11016017B2 (en) 2016-06-10 2021-05-25 The Regents Of The University Of California Image-based cell sorting systems and methods
US20190257736A1 (en) * 2016-06-21 2019-08-22 Synelixis AB System and Method for Precision Deposition of Liquid Droplets
US10544413B2 (en) 2017-05-18 2020-01-28 10X Genomics, Inc. Methods and systems for sorting droplets and beads
CN117143960A (zh) 2017-05-18 2023-12-01 10X基因组学有限公司 用于分选液滴和珠的方法和系统
US10610865B2 (en) 2017-08-22 2020-04-07 10X Genomics, Inc. Droplet forming devices and system with differential surface properties
WO2019083852A1 (en) 2017-10-26 2019-05-02 10X Genomics, Inc. MICROFLUIDIC CHANNEL NETWORKS FOR PARTITIONING
EP3785015B1 (en) 2018-04-27 2024-06-26 Becton, Dickinson and Company Flow cytometers having enclosed droplet sorters with controlled aerosol content and methods of using the same
WO2020163023A1 (en) 2019-02-08 2020-08-13 Becton, Dickinson And Company Droplet sorting decision modules, systems and methods of use thereof
CN109916803A (zh) * 2019-02-27 2019-06-21 苏州朗如精密机械科技有限公司 一种流式细胞分析仪样本分选检测模块及其全自动分选检测方法
EP3956649A4 (en) * 2019-04-19 2023-01-04 Becton, Dickinson and Company UNDERSAMPLING FLOW CYTOMETRIC EVENT DATA
CN112730408B (zh) * 2020-12-24 2024-07-09 贝克曼库尔特生物科技（苏州）有限公司 液流检测系统和液流检测方法以及分选装置
CN115824736B (zh) * 2022-11-10 2023-10-20 东西分析仪器(天津)有限公司 一种微量样品点样头
CN115962995B (zh) * 2022-12-26 2023-07-04 中国科学院基础医学与肿瘤研究所(筹) 一种全自动微生物染色制片装置
CN118681609B (zh) * 2023-03-24 2026-02-13 深圳华大生命科学研究院 液滴微流控分选方法、分选系统、电子设备及存储介质

Citations (3)

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US4347935A (en) * 1979-05-16 1982-09-07 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for electrostatically sorting biological cells
US5617911A (en) * 1995-09-08 1997-04-08 Aeroquip Corporation Method and apparatus for creating a free-form three-dimensional article using a layer-by-layer deposition of a support material and a deposition material
US6589792B1 (en) * 1998-02-27 2003-07-08 Dakocytomation Denmark A/S Method and apparatus for flow cytometry

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JPS62167478A (ja) * 1985-11-29 1987-07-23 Shimadzu Corp 粒子分取装置
US4981580A (en) * 1989-05-01 1991-01-01 Coulter Corporation Coincidence arbitration in a flow cytomery sorting system
US5199576A (en) * 1991-04-05 1993-04-06 University Of Rochester System for flexibly sorting particles
US5483469A (en) * 1993-08-02 1996-01-09 The Regents Of The University Of California Multiple sort flow cytometer
US6281018B1 (en) * 1998-02-26 2001-08-28 Coulter International Corp. Selective purification and enrichment sorting of flow cytometer droplets based upon analysis of droplet precursor regions
US6211477B1 (en) * 1998-02-26 2001-04-03 Becton Dickinson And Company Electrostatic deceleration system for flow cytometer
US6079836A (en) * 1998-07-20 2000-06-27 Coulter International Corp. Flow cytometer droplet break-off location adjustment mechanism
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
EP1468266A4 (en) * 2002-01-22 2009-03-11 Beckman Coulter Inc ENVIRONMENTALLY COMPLETED SYSTEM FOR A FLOW CYTOMETER
US20110177547A1 (en) * 2004-12-10 2011-07-21 Arryx, Inc. Particle Sorting Using Fluid Streams
US8290625B2 (en) 2007-04-04 2012-10-16 Beckman Coulter, Inc. Flow cytometer sorter
US7691636B2 (en) * 2007-05-23 2010-04-06 Beckman Coulter, Inc. Method and apparatus for compensating for variations in particle trajectories in electrostatic sorter for flowcell cytometer
JP4990746B2 (ja) * 2007-12-14 2012-08-01 ベイバイオサイエンス株式会社 液体フローに含まれる生物学的粒子を分別する装置ならびにその方法
US8140300B2 (en) * 2008-05-15 2012-03-20 Becton, Dickinson And Company High throughput flow cytometer operation with data quality assessment and control
JP5446563B2 (ja) 2009-08-06 2014-03-19 ソニー株式会社 微小粒子分取装置、および該微小粒子分取装置を用いたフローサイトメーター
JP2011237201A (ja) 2010-05-06 2011-11-24 Sony Corp 微小粒子分取装置、マイクロチップ及びマイクロチップモジュール
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US4347935A (en) * 1979-05-16 1982-09-07 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for electrostatically sorting biological cells
US5617911A (en) * 1995-09-08 1997-04-08 Aeroquip Corporation Method and apparatus for creating a free-form three-dimensional article using a layer-by-layer deposition of a support material and a deposition material
US6589792B1 (en) * 1998-02-27 2003-07-08 Dakocytomation Denmark A/S Method and apparatus for flow cytometry

Also Published As

Publication number Publication date
CN104204768A (zh) 2014-12-10
EP2812671B1 (en) 2019-12-25
EP2812671A1 (en) 2014-12-17
AU2013216878A1 (en) 2014-08-28
US20150050688A1 (en) 2015-02-19
JP6192665B2 (ja) 2017-09-06
CN104204768B (zh) 2018-07-10
SG11201404780VA (en) 2014-09-26
IN2014DN06692A (enExample) 2015-05-22
ES2776157T3 (es) 2020-07-29
US10190959B2 (en) 2019-01-29
WO2013119924A1 (en) 2013-08-15
JP2015507204A (ja) 2015-03-05

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