CN104203277A - 梯牧草变应原和用于调节免疫反应的方法和用途 - Google Patents
梯牧草变应原和用于调节免疫反应的方法和用途 Download PDFInfo
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- 229940083466 soybean lecithin Drugs 0.000 description 1
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- 230000002195 synergetic effect Effects 0.000 description 1
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- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 238000004885 tandem mass spectrometry Methods 0.000 description 1
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- 229940040944 tetracyclines Drugs 0.000 description 1
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- 229960000707 tobramycin Drugs 0.000 description 1
- NLVFBUXFDBBNBW-PBSUHMDJSA-S tobramycin(5+) Chemical compound [NH3+][C@@H]1C[C@H](O)[C@@H](C[NH3+])O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H]([NH3+])[C@H](O)[C@@H](CO)O2)O)[C@H]([NH3+])C[C@@H]1[NH3+] NLVFBUXFDBBNBW-PBSUHMDJSA-S 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
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- 238000013519 translation Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 description 1
- 229940029284 trichlorofluoromethane Drugs 0.000 description 1
- VSQQQLOSPVPRAZ-RRKCRQDMSA-N trifluridine Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(C(F)(F)F)=C1 VSQQQLOSPVPRAZ-RRKCRQDMSA-N 0.000 description 1
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- 229940093257 valacyclovir Drugs 0.000 description 1
- 229960003165 vancomycin Drugs 0.000 description 1
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- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A61K39/36—Allergens from pollen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Botany (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
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| US201261596156P | 2012-02-07 | 2012-02-07 | |
| US61/596,156 | 2012-02-07 | ||
| US201261734886P | 2012-12-07 | 2012-12-07 | |
| US61/734,886 | 2012-12-07 | ||
| PCT/US2013/025213 WO2013119863A1 (en) | 2012-02-07 | 2013-02-07 | Timothy grass allergens and methods and uses for immune response modulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104203277A true CN104203277A (zh) | 2014-12-10 |
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| US (1) | US10428124B2 (enExample) |
| EP (1) | EP2812026A4 (enExample) |
| JP (1) | JP2015513527A (enExample) |
| KR (1) | KR20140129124A (enExample) |
| CN (1) | CN104203277A (enExample) |
| AU (1) | AU2013216993C1 (enExample) |
| BR (1) | BR112014019504A2 (enExample) |
| CA (1) | CA2864084A1 (enExample) |
| EA (1) | EA201491481A1 (enExample) |
| HK (1) | HK1204929A1 (enExample) |
| IN (1) | IN2014MN01513A (enExample) |
| MX (1) | MX2014009285A (enExample) |
| WO (1) | WO2013119863A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12201652B2 (en) * | 2016-05-03 | 2025-01-21 | Stemcell Technologies Canada Inc. | Intracellular delivery of biomolecules to induce tolerance |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015054217A2 (en) | 2013-10-07 | 2015-04-16 | La Jolla Institute For Allergy And Immunology | Methods and uses for reducing an allergic response in a subject |
| WO2015054231A1 (en) | 2013-10-07 | 2015-04-16 | La Jolla Institute For Allergy And Immunology | Methods and uses for identifying responders to allergy therapy |
| WO2015077442A2 (en) | 2013-11-20 | 2015-05-28 | La Jolla Institute For Allergy And Immunology | Grass pollen immunogens and methods and uses for immune response modulation |
| EA201691028A1 (ru) | 2013-11-20 | 2017-01-30 | Ла Хойя Инститьют Фор Эллерджи Энд Иммьюнолоджи | Пан-иммуногены пыльцы, способы и применение для модуляции иммунного ответа |
| CA2933552A1 (en) | 2013-12-23 | 2015-07-02 | Alk-Abello A/S | Peptide combinations and uses thereof in treating dust mite allergy |
| WO2015131053A1 (en) | 2014-02-28 | 2015-09-03 | Alk-Abelló A/S | Polypeptides derived from phl p and methods and uses thereof for immune response modulation |
| JP6423889B2 (ja) * | 2014-10-07 | 2018-11-14 | サイトリミック株式会社 | Ｈｓｐ７０由来のペプチド、これを用いた癌の治療又は予防のための医薬組成物、免疫誘導剤、及び抗原提示細胞の製造方法 |
| EP3269733B1 (en) | 2015-03-09 | 2020-06-17 | Cytlimic Inc. | Peptide derived from gpc3, pharmaceutical composition for treatment or prevention of cancer using same, immunity inducer, and method for producing antigen-presenting cells |
| US10842848B2 (en) | 2015-04-07 | 2020-11-24 | Cytlimic Inc. | Method for treating cancer by adminstering poly I:C and LAG-3-IgG fusion protein |
| EP3527216B1 (en) | 2016-10-11 | 2024-02-14 | NEC Corporation | A medicine comprising a toll-like receptor agonist, lag-3 protein, a hsp70-derived peptide and a gpc3-derived peptide |
| WO2018199341A1 (ja) * | 2017-04-28 | 2018-11-01 | 学校法人藤田学園 | アレルギーの抗原およびそのエピトープ |
| CN114729929B (zh) * | 2019-11-25 | 2025-10-28 | 加利福尼亚大学董事会 | 诊断和治疗自闭症的抗原神经元特异性烯醇化酶肽 |
| CN120349374B (zh) * | 2025-03-25 | 2025-10-10 | 长沙理工大学 | 一种米渣短肽及其在降尿酸中的应用 |
Citations (4)
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| CN1665835A (zh) * | 2002-06-25 | 2005-09-07 | 默克专利股份公司 | 草花粉过敏原Phl p4 的 DNA 序列和用重组方法进行的制备 |
| CN1675240A (zh) * | 2002-08-19 | 2005-09-28 | 默克专利股份公司 | 来自梯牧草的主要过敏原Phl p1的变异体 |
| US20090070897A1 (en) * | 2006-01-12 | 2009-03-12 | Goldman Barry S | Genes and uses for plant improvement |
| US20110217325A1 (en) * | 2001-09-18 | 2011-09-08 | Circassia Limited | T cell epitopes of the cyn d 1 allergen from bermuda grass pollen |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7214786B2 (en) * | 2000-12-14 | 2007-05-08 | Kovalic David K | Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement |
| MXPA05005528A (es) | 2002-11-26 | 2006-04-05 | Alk Abello As | Producto farmaceutico de alergeno. |
| EP3059306A1 (en) * | 2005-01-12 | 2016-08-24 | Monsanto Technology LLC | Genes and uses for plant improvement |
| ES2950396T3 (es) * | 2008-02-01 | 2023-10-09 | Prota Therapeutics Pty Ltd | Un método para inducir tolerancia a un alérgeno |
| EP2388268A1 (en) * | 2010-05-18 | 2011-11-23 | Stallergenes S.A. | Recombinant Der p 2 expressed in Pichia pastoris as a "natural-like" allergen for immunotherapy and diagnostic purposes |
| KR20130118884A (ko) | 2010-10-15 | 2013-10-30 | 알크-아벨로 에이/에스 | 알레르겐 소스 물질로부터 유도된 무관련 알레르겐을 이용한 과민성 면역반응의 억제 |
| US20120100163A1 (en) | 2010-10-15 | 2012-04-26 | Alk-Abello A/S | Suppression of a type 1 hypersensitivity immune response with an unrelated antigen |
| EP2831102A4 (en) | 2012-03-26 | 2015-12-02 | Pronutria Inc | NUTRITIONAL FRAGMENTS, PROTEINS THEREFOR AND METHOD |
| CA2870399A1 (en) | 2012-04-16 | 2013-10-24 | Alk-Abello A/S | Plant profilin polypeptides for use in non-specific allergy immunotherapy |
-
2013
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- 2013-02-07 JP JP2014556692A patent/JP2015513527A/ja active Pending
- 2013-02-07 MX MX2014009285A patent/MX2014009285A/es unknown
- 2013-02-07 US US14/375,980 patent/US10428124B2/en active Active
- 2013-02-07 CA CA2864084A patent/CA2864084A1/en not_active Abandoned
- 2013-02-07 HK HK15105520.1A patent/HK1204929A1/xx unknown
- 2013-02-07 IN IN1513MUN2014 patent/IN2014MN01513A/en unknown
- 2013-02-07 BR BR112014019504A patent/BR112014019504A2/pt not_active IP Right Cessation
- 2013-02-07 AU AU2013216993A patent/AU2013216993C1/en not_active Ceased
- 2013-02-07 WO PCT/US2013/025213 patent/WO2013119863A1/en not_active Ceased
- 2013-02-07 EA EA201491481A patent/EA201491481A1/ru unknown
- 2013-02-07 EP EP13747032.4A patent/EP2812026A4/en not_active Withdrawn
- 2013-02-07 CN CN201380008385.XA patent/CN104203277A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110217325A1 (en) * | 2001-09-18 | 2011-09-08 | Circassia Limited | T cell epitopes of the cyn d 1 allergen from bermuda grass pollen |
| CN1665835A (zh) * | 2002-06-25 | 2005-09-07 | 默克专利股份公司 | 草花粉过敏原Phl p4 的 DNA 序列和用重组方法进行的制备 |
| CN1675240A (zh) * | 2002-08-19 | 2005-09-28 | 默克专利股份公司 | 来自梯牧草的主要过敏原Phl p1的变异体 |
| US20090070897A1 (en) * | 2006-01-12 | 2009-03-12 | Goldman Barry S | Genes and uses for plant improvement |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12201652B2 (en) * | 2016-05-03 | 2025-01-21 | Stemcell Technologies Canada Inc. | Intracellular delivery of biomolecules to induce tolerance |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2864084A1 (en) | 2013-08-15 |
| AU2013216993A1 (en) | 2014-08-21 |
| EA201491481A1 (ru) | 2014-11-28 |
| HK1204929A1 (en) | 2015-12-11 |
| MX2014009285A (es) | 2015-02-04 |
| EP2812026A1 (en) | 2014-12-17 |
| BR112014019504A2 (pt) | 2017-06-27 |
| AU2013216993C1 (en) | 2017-01-19 |
| AU2013216993B2 (en) | 2016-09-15 |
| JP2015513527A (ja) | 2015-05-14 |
| US10428124B2 (en) | 2019-10-01 |
| KR20140129124A (ko) | 2014-11-06 |
| IN2014MN01513A (enExample) | 2015-09-11 |
| EP2812026A4 (en) | 2016-04-27 |
| WO2013119863A1 (en) | 2013-08-15 |
| US20150023992A1 (en) | 2015-01-22 |
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