AU2013216993C1 - Timothy Grass allergens and methods and uses for immune response modulation - Google Patents

Timothy Grass allergens and methods and uses for immune response modulation Download PDF

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Publication number
AU2013216993C1
AU2013216993C1 AU2013216993A AU2013216993A AU2013216993C1 AU 2013216993 C1 AU2013216993 C1 AU 2013216993C1 AU 2013216993 A AU2013216993 A AU 2013216993A AU 2013216993 A AU2013216993 A AU 2013216993A AU 2013216993 C1 AU2013216993 C1 AU 2013216993C1
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Australia
Prior art keywords
seq
nos
amino acid
protein
peptide
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AU2013216993A
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English (en)
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AU2013216993A1 (en
AU2013216993B2 (en
Inventor
Jason GREENBAUM
Howard Grey
Bjoern Peters
Veronique SCHULTEN
Alessandro Sette
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La Jolla Institute for Allergy and Immunology
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La Jolla Institute for Allergy and Immunology
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Publication of AU2013216993A1 publication Critical patent/AU2013216993A1/en
Assigned to LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY reassignment LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY Amend patent request/document other than specification (104) Assignors: ALESSANDRO SETTE, BJOERN PETERS, HOWARD GREY, JASON GREENBAUM, LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY, VERONIQUE SCHULTEN
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Publication of AU2013216993B2 publication Critical patent/AU2013216993B2/en
Publication of AU2013216993C1 publication Critical patent/AU2013216993C1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2013216993A 2012-02-07 2013-02-07 Timothy Grass allergens and methods and uses for immune response modulation Ceased AU2013216993C1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261596156P 2012-02-07 2012-02-07
US61/596,156 2012-02-07
US201261734886P 2012-12-07 2012-12-07
US61/734,886 2012-12-07
PCT/US2013/025213 WO2013119863A1 (en) 2012-02-07 2013-02-07 Timothy grass allergens and methods and uses for immune response modulation

Publications (3)

Publication Number Publication Date
AU2013216993A1 AU2013216993A1 (en) 2014-08-21
AU2013216993B2 AU2013216993B2 (en) 2016-09-15
AU2013216993C1 true AU2013216993C1 (en) 2017-01-19

Family

ID=48948025

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013216993A Ceased AU2013216993C1 (en) 2012-02-07 2013-02-07 Timothy Grass allergens and methods and uses for immune response modulation

Country Status (13)

Country Link
US (1) US10428124B2 (enExample)
EP (1) EP2812026A4 (enExample)
JP (1) JP2015513527A (enExample)
KR (1) KR20140129124A (enExample)
CN (1) CN104203277A (enExample)
AU (1) AU2013216993C1 (enExample)
BR (1) BR112014019504A2 (enExample)
CA (1) CA2864084A1 (enExample)
EA (1) EA201491481A1 (enExample)
HK (1) HK1204929A1 (enExample)
IN (1) IN2014MN01513A (enExample)
MX (1) MX2014009285A (enExample)
WO (1) WO2013119863A1 (enExample)

Families Citing this family (14)

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WO2015054217A2 (en) 2013-10-07 2015-04-16 La Jolla Institute For Allergy And Immunology Methods and uses for reducing an allergic response in a subject
WO2015054231A1 (en) 2013-10-07 2015-04-16 La Jolla Institute For Allergy And Immunology Methods and uses for identifying responders to allergy therapy
WO2015077442A2 (en) 2013-11-20 2015-05-28 La Jolla Institute For Allergy And Immunology Grass pollen immunogens and methods and uses for immune response modulation
EA201691028A1 (ru) 2013-11-20 2017-01-30 Ла Хойя Инститьют Фор Эллерджи Энд Иммьюнолоджи Пан-иммуногены пыльцы, способы и применение для модуляции иммунного ответа
CA2933552A1 (en) 2013-12-23 2015-07-02 Alk-Abello A/S Peptide combinations and uses thereof in treating dust mite allergy
WO2015131053A1 (en) 2014-02-28 2015-09-03 Alk-Abelló A/S Polypeptides derived from phl p and methods and uses thereof for immune response modulation
JP6423889B2 (ja) * 2014-10-07 2018-11-14 サイトリミック株式会社 Ｈｓｐ７０由来のペプチド、これを用いた癌の治療又は予防のための医薬組成物、免疫誘導剤、及び抗原提示細胞の製造方法
EP3269733B1 (en) 2015-03-09 2020-06-17 Cytlimic Inc. Peptide derived from gpc3, pharmaceutical composition for treatment or prevention of cancer using same, immunity inducer, and method for producing antigen-presenting cells
US10842848B2 (en) 2015-04-07 2020-11-24 Cytlimic Inc. Method for treating cancer by adminstering poly I:C and LAG-3-IgG fusion protein
KR102430856B1 (ko) * 2016-05-03 2022-08-08 에스큐지 바이오테크놀로지스 컴퍼니 관용을 유도하는 생체분자의 세포내 전달
EP3527216B1 (en) 2016-10-11 2024-02-14 NEC Corporation A medicine comprising a toll-like receptor agonist, lag-3 protein, a hsp70-derived peptide and a gpc3-derived peptide
WO2018199341A1 (ja) * 2017-04-28 2018-11-01 学校法人藤田学園 アレルギーの抗原およびそのエピトープ
CN114729929B (zh) * 2019-11-25 2025-10-28 加利福尼亚大学董事会 诊断和治疗自闭症的抗原神经元特异性烯醇化酶肽
CN120349374B (zh) * 2025-03-25 2025-10-10 长沙理工大学 一种米渣短肽及其在降尿酸中的应用

Citations (1)

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US20090070897A1 (en) * 2006-01-12 2009-03-12 Goldman Barry S Genes and uses for plant improvement

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US7214786B2 (en) * 2000-12-14 2007-05-08 Kovalic David K Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
AUPR775401A0 (en) * 2001-09-18 2001-10-11 Monash University Novel Epitopes and Uses Thereof
ES2384045T3 (es) 2002-06-25 2012-06-28 Merck Patent Gmbh Secuencia de ADN y preparación recombinante del alérgeno del polen de gramíneas PHI P 4
AU2003251674B2 (en) * 2002-08-19 2009-09-03 Merck Patent Gmbh Variants of the major allergen Phl p 1 from timothy grass
MXPA05005528A (es) 2002-11-26 2006-04-05 Alk Abello As Producto farmaceutico de alergeno.
EP3059306A1 (en) * 2005-01-12 2016-08-24 Monsanto Technology LLC Genes and uses for plant improvement
ES2950396T3 (es) * 2008-02-01 2023-10-09 Prota Therapeutics Pty Ltd Un método para inducir tolerancia a un alérgeno
EP2388268A1 (en) * 2010-05-18 2011-11-23 Stallergenes S.A. Recombinant Der p 2 expressed in Pichia pastoris as a "natural-like" allergen for immunotherapy and diagnostic purposes
KR20130118884A (ko) 2010-10-15 2013-10-30 알크-아벨로 에이/에스 알레르겐 소스 물질로부터 유도된 무관련 알레르겐을 이용한 과민성 면역반응의 억제
US20120100163A1 (en) 2010-10-15 2012-04-26 Alk-Abello A/S Suppression of a type 1 hypersensitivity immune response with an unrelated antigen
EP2831102A4 (en) 2012-03-26 2015-12-02 Pronutria Inc NUTRITIONAL FRAGMENTS, PROTEINS THEREFOR AND METHOD
CA2870399A1 (en) 2012-04-16 2013-10-24 Alk-Abello A/S Plant profilin polypeptides for use in non-specific allergy immunotherapy

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US20090070897A1 (en) * 2006-01-12 2009-03-12 Goldman Barry S Genes and uses for plant improvement

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CORTI, V. et al. :"Identification of grass pollen allergens by two-dimensional gel electrophoresis and serological screening",Proteomics, 2005, Vol.5, pages 729-736 *
PERSSON, H. et al.: "A common idiotype in IgE and its relation to recognition of the grass pollen allergen Phl p 2", Molecular Immunology, 2008, Vol.45, pages 2715-2720 *
VRTALA, S. et al., "cDNA Cloning of a Major Allergen from Timothy Grass (Phleum pratense) Pollen; Characterization of the Recombinant Phl p V Allergen", The Journal of Immunology, (1993), Vol. 151, No.9 pages 4773-4781 *

Also Published As

Publication number Publication date
CN104203277A (zh) 2014-12-10
CA2864084A1 (en) 2013-08-15
AU2013216993A1 (en) 2014-08-21
EA201491481A1 (ru) 2014-11-28
HK1204929A1 (en) 2015-12-11
MX2014009285A (es) 2015-02-04
EP2812026A1 (en) 2014-12-17
BR112014019504A2 (pt) 2017-06-27
AU2013216993B2 (en) 2016-09-15
JP2015513527A (ja) 2015-05-14
US10428124B2 (en) 2019-10-01
KR20140129124A (ko) 2014-11-06
IN2014MN01513A (enExample) 2015-09-11
EP2812026A4 (en) 2016-04-27
WO2013119863A1 (en) 2013-08-15
US20150023992A1 (en) 2015-01-22

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Legal Events

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ TIMOTHY GRASS ALLERGENS AND METHODS AND USES FOR IMMUNE RESPONSE MODULATION

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ TIMOTHY GRASS ALLERGENS AND METHODS AND USES FOR IMMUNE RESPONSE MODULATION

TH Corrigenda

Free format text: IN VOL 28 , NO 32 , PAGE(S) 4294 UNDER THE HEADING AMENDMENTS - AMENDMENTS MADE DELETE ALL REFERENCES TO 2013216993

DA2 Applications for amendment section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 22 SEP 2016

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 22 SEP 2016

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired