AU2013216993C1 - Timothy Grass allergens and methods and uses for immune response modulation - Google Patents

Timothy Grass allergens and methods and uses for immune response modulation Download PDF

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Publication number
AU2013216993C1
AU2013216993C1 AU2013216993A AU2013216993A AU2013216993C1 AU 2013216993 C1 AU2013216993 C1 AU 2013216993C1 AU 2013216993 A AU2013216993 A AU 2013216993A AU 2013216993 A AU2013216993 A AU 2013216993A AU 2013216993 C1 AU2013216993 C1 AU 2013216993C1
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AU
Australia
Prior art keywords
seq
nos
amino acid
protein
peptide
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Ceased
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AU2013216993A
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English (en)
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AU2013216993B2 (en
AU2013216993A1 (en
Inventor
Jason GREENBAUM
Howard Grey
Bjoern Peters
Veronique SCHULTEN
Alessandro Sette
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La Jolla Institute For Allergy & Immunology
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La Jolla Institute For Allergy & Immunology
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Publication of AU2013216993A1 publication Critical patent/AU2013216993A1/en
Assigned to LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY reassignment LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY Amend patent request/document other than specification (104) Assignors: ALESSANDRO SETTE, BJOERN PETERS, HOWARD GREY, JASON GREENBAUM, LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY, VERONIQUE SCHULTEN
Publication of AU2013216993B2 publication Critical patent/AU2013216993B2/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
AU2013216993A 2012-02-07 2013-02-07 Timothy Grass allergens and methods and uses for immune response modulation Ceased AU2013216993C1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261596156P 2012-02-07 2012-02-07
US61/596,156 2012-02-07
US201261734886P 2012-12-07 2012-12-07
US61/734,886 2012-12-07
PCT/US2013/025213 WO2013119863A1 (en) 2012-02-07 2013-02-07 Timothy grass allergens and methods and uses for immune response modulation

Publications (3)

Publication Number Publication Date
AU2013216993A1 AU2013216993A1 (en) 2014-08-21
AU2013216993B2 AU2013216993B2 (en) 2016-09-15
AU2013216993C1 true AU2013216993C1 (en) 2017-01-19

Family

ID=48948025

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013216993A Ceased AU2013216993C1 (en) 2012-02-07 2013-02-07 Timothy Grass allergens and methods and uses for immune response modulation

Country Status (13)

Country Link
US (1) US10428124B2 (enExample)
EP (1) EP2812026A4 (enExample)
JP (1) JP2015513527A (enExample)
KR (1) KR20140129124A (enExample)
CN (1) CN104203277A (enExample)
AU (1) AU2013216993C1 (enExample)
BR (1) BR112014019504A2 (enExample)
CA (1) CA2864084A1 (enExample)
EA (1) EA201491481A1 (enExample)
HK (1) HK1204929A1 (enExample)
IN (1) IN2014MN01513A (enExample)
MX (1) MX2014009285A (enExample)
WO (1) WO2013119863A1 (enExample)

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Publication number Priority date Publication date Assignee Title
WO2015054217A2 (en) 2013-10-07 2015-04-16 La Jolla Institute For Allergy And Immunology Methods and uses for reducing an allergic response in a subject
WO2015054231A1 (en) 2013-10-07 2015-04-16 La Jolla Institute For Allergy And Immunology Methods and uses for identifying responders to allergy therapy
EA201691028A1 (ru) 2013-11-20 2017-01-30 Ла Хойя Инститьют Фор Эллерджи Энд Иммьюнолоджи Пан-иммуногены пыльцы, способы и применение для модуляции иммунного ответа
WO2015077442A2 (en) 2013-11-20 2015-05-28 La Jolla Institute For Allergy And Immunology Grass pollen immunogens and methods and uses for immune response modulation
CN105848677B (zh) 2013-12-23 2020-01-31 爱尔开-阿贝优公司 在治疗尘螨过敏症中的肽组合及其用途
WO2015131053A1 (en) 2014-02-28 2015-09-03 Alk-Abelló A/S Polypeptides derived from phl p and methods and uses thereof for immune response modulation
WO2016056596A1 (ja) * 2014-10-07 2016-04-14 日本電気株式会社 Ｈｓｐ７０由来のペプチド、これを用いた癌の治療又は予防のための医薬組成物、免疫誘導剤、及び抗原提示細胞の製造方法
US10526388B2 (en) 2015-03-09 2020-01-07 Cytlimic Inc. Peptide derived from GPC3, pharmaceutical composition for treatment or prevention of cancer using the same, immunity inducer, and method for producing antigen-presenting cells
AU2016244570B2 (en) 2015-04-07 2020-08-27 Nec Corporation Medicine
CN109415741A (zh) * 2016-05-03 2019-03-01 Sqz生物技术公司 细胞内递送生物分子以诱导耐受性
US11291718B2 (en) 2016-10-11 2022-04-05 Cytlimic Inc. Method for treating cancer by administering a toll-like receptor agonist and LAG-3 IgG fusion protein
KR20260017488A (ko) * 2017-04-28 2026-02-05 호유 가부시키가이샤 알레르기 항원 및 그 에피토프
JP7770314B2 (ja) * 2019-11-25 2025-11-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 診断及び処置のための抗原ニューロン特異的エノラーゼペプチド
CN120349374B (zh) * 2025-03-25 2025-10-10 长沙理工大学 一种米渣短肽及其在降尿酸中的应用

Citations (1)

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US20090070897A1 (en) * 2006-01-12 2009-03-12 Goldman Barry S Genes and uses for plant improvement

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US7214786B2 (en) * 2000-12-14 2007-05-08 Kovalic David K Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
AUPR775401A0 (en) 2001-09-18 2001-10-11 Monash University Novel Epitopes and Uses Thereof
ES2384045T3 (es) * 2002-06-25 2012-06-28 Merck Patent Gmbh Secuencia de ADN y preparación recombinante del alérgeno del polen de gramíneas PHI P 4
US7731970B2 (en) 2002-08-19 2010-06-08 Merck Patent Gmbh Variants of the major allergen Phl p 1 from timothy grass
WO2004047793A1 (en) 2002-11-26 2004-06-10 Alk-Abelló A/S Pharmaceutical allergen product
WO2006076423A2 (en) 2005-01-12 2006-07-20 Monsanto Technology, Llc Genes and uses for plant improvement
SI2244734T1 (sl) * 2008-02-01 2016-11-30 Murdoch Childrens Research Institute Postopek induciranja tolerance na alergen
EP2388268A1 (en) 2010-05-18 2011-11-23 Stallergenes S.A. Recombinant Der p 2 expressed in Pichia pastoris as a "natural-like" allergen for immunotherapy and diagnostic purposes
US20120100163A1 (en) 2010-10-15 2012-04-26 Alk-Abello A/S Suppression of a type 1 hypersensitivity immune response with an unrelated antigen
BR112013009068A2 (pt) 2010-10-15 2016-07-19 Alk Abelló As supressão de uma resposta imune de hipersensibilidade com antígeno não relacionado derivado de material fonte de alérgeno
CA2868469A1 (en) * 2012-03-26 2013-10-03 Pronutria, Inc. Nutritive fragments, proteins and methods
JP2015514126A (ja) 2012-04-16 2015-05-18 アルク−アベッロ エイ／エスＡｌｋ−Ａｂｅｌｌｏ Ａ／Ｓ 非特異的アレルギー免疫療法において使用するための植物プロフィリンポリペプチド

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US20090070897A1 (en) * 2006-01-12 2009-03-12 Goldman Barry S Genes and uses for plant improvement

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CORTI, V. et al. :"Identification of grass pollen allergens by two-dimensional gel electrophoresis and serological screening",Proteomics, 2005, Vol.5, pages 729-736 *
PERSSON, H. et al.: "A common idiotype in IgE and its relation to recognition of the grass pollen allergen Phl p 2", Molecular Immunology, 2008, Vol.45, pages 2715-2720 *
VRTALA, S. et al., "cDNA Cloning of a Major Allergen from Timothy Grass (Phleum pratense) Pollen; Characterization of the Recombinant Phl p V Allergen", The Journal of Immunology, (1993), Vol. 151, No.9 pages 4773-4781 *

Also Published As

Publication number Publication date
CN104203277A (zh) 2014-12-10
IN2014MN01513A (enExample) 2015-09-11
BR112014019504A2 (pt) 2017-06-27
AU2013216993B2 (en) 2016-09-15
HK1204929A1 (en) 2015-12-11
EP2812026A4 (en) 2016-04-27
EA201491481A1 (ru) 2014-11-28
EP2812026A1 (en) 2014-12-17
JP2015513527A (ja) 2015-05-14
CA2864084A1 (en) 2013-08-15
MX2014009285A (es) 2015-02-04
US20150023992A1 (en) 2015-01-22
US10428124B2 (en) 2019-10-01
AU2013216993A1 (en) 2014-08-21
KR20140129124A (ko) 2014-11-06
WO2013119863A1 (en) 2013-08-15

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Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ TIMOTHY GRASS ALLERGENS AND METHODS AND USES FOR IMMUNE RESPONSE MODULATION

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ TIMOTHY GRASS ALLERGENS AND METHODS AND USES FOR IMMUNE RESPONSE MODULATION

TH Corrigenda

Free format text: IN VOL 28 , NO 32 , PAGE(S) 4294 UNDER THE HEADING AMENDMENTS - AMENDMENTS MADE DELETE ALL REFERENCES TO 2013216993

DA2 Applications for amendment section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 22 SEP 2016

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 22 SEP 2016

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired