CN104189664A - Lymphatic tuberculosis promoting qi and activating blood preparation and preparation method thereof - Google Patents

Abstract

The invention discloses a lymphatic tuberculosis promoting qi and activating blood preparation which is prepared by the following bulk drugs in part by weight: 5 to 12 parts of gleditschia horrida wood veneer, 6 to 15 parts of flos chrysanthemi indici, 3 to 9 parts of balloonflower, 5 to 15 parts of cutworm, 6 to 10 parts of scutellaria root, 4 to 8 parts of smilax ocreafa A. DC, 6 to 9 parts of annual fleabane, 6 to 15 parts of fleece-flower rootv, 18 to 32 parts of Bridelia fordii Hemsl, 15 to 25 parts of selfheal spike, 6 to 12 parts of forsythia fruit, 5 to 12 parts of rock sajong, and 6 to 15 parts of ecklonia. The preparation has the excellent effects that material selected is traditional Chinese medicine material, the preparation does not have any toxic and side effects, the compatibility of prescription is accurate, the curative effect of lymphatic tuberculosis is quick, the course of treatment is short, the preparation has the effects of promoting qi to activate blood, removing blood stasis and dispersing phlegm, warming and activating meridian, and the like, the drug action of the prescription is everlasting, and the everlasting can not only soothe exterior cold syndrome, but also eliminate an old complaint, and achieves the purpose of treating both principal and secondary aspect of disease.

Description

The agent of lymphoid tuberculosis promoting flow of QI and blood and method for making

Technical field

The present invention relates to Chinese medicine field, particularly relate to the agent of a kind of lymphoid tuberculosis promoting flow of QI and blood and method for making.

Background technology

Lymphoid tuberculosis, the traditional Chinese medical science is referred to as scrofula, is the malicious block organization that is embodied in flesh table, is to be become by the scorchingly hot poison cohesion of expectorant of liver lung two aspects.Doctor trained in Western medicine refers to, kills virus and protects the lymphsystem of vascular tissue thereby have in human body to specialize in detoxicating, outside meeting ex vivo, cannot remove the toadstool of killing, and condenses and assembles in the malignant tumor of flesh table organization formation.

Lymphoid tuberculosis is often because of anxiety and rage, depression of liver-QI, and dysfunction of the spleen in transportation, raw in phlegm-damp, stagnation of QI expectorant is solidifying, hinders in passages through which vital energy circulates, ties in neck, forms this disease.With the passing of time phlegm-damp heat-transformation, or pathogenic fire derived from stagnation of liver-QI, lower bright kidney yin, hyperactivity of heat bringing about rottenness of muscle becomes pus, and ulceration becomes skin ulcer, and pus is dripping, and the cloudy Tianjin of wasting QI-blood, gradually becomes deficiency syndrome.Also can be because of deficiency of YIN of both the lung and kidney, so that hyperactivity of fire caused by deficiency of YIN, lung Tianjin can not defeated cloth, and bright Tianjin is expectorant, and phlegm-fire condenses, and ties due to the neck.At the scrofula initial stage, lump is solid, without obvious General Symptoms, dialectically coagulates as main taking stagnation of QI expectorant; Metaphase nucleus piece increases gradually, and with skin adhesion, it is dark red that color of the leather turns, and inside suppurates gradually.Often with General Symptoms as hectic fever in the afternoon, Sleep hyperhidrosis, red tongue, few tongue, thready and rapid pulse, the dialectical hyperactivity of fire caused by deficiency of YIN that mostly is; To the later stage, pus becomes ulceration, and open sore part pus goes out rare clearly, accompanies worn-out cotton wadding for quilt sample thing, often accompanies emaciated physique, tired mind, lusterless complexion.Light red tongue, thin fur, the symptoms such as thready pulse.Some patient, General Symptoms is also not obvious, only suppurates with lymphadenectasis or ulceration medical, now dialectical should drawing according to local lump variation.Lump is solid, and it is main that many stagnation of QIs expectorant coagulates, and lump deliquescing is suppurated, and Sthenia is transforming into asthenia gradually, to ulceration person, and common deficiency of both QI and blood.Dialectical the treating of the many employings of the traditional Chinese medical science, effect is better.

When western medical treatment treatment lymphoid tuberculosis, to the lighter nodular type of the state of an illness or infiltrative type and without the patient of General Symptoms, generally only adopt oral isoniazid 1-2; With systemic toxic symptoms or the health elsewhere person that has tuberculosis, add sodium aminosalicylate or rifampicin or add and use intramuscular injection.And to having the patient of abscess or ulcer type, should adopt surgical resection and rinse in conjunction with antituberculosis drugs thing, also to take antituberculotics simultaneously.Lymphoid tuberculosis relapse rate is high.And the therapeutic effect of the traditional Chinese medical science is relatively better.

Publication number CN 1814212 A(application numbers 200510128097.5) Chinese invention patent disclose one and treated scrofulous herbal decoction and preparation method, this Chinese herbal medicine formula is 5 grams of Squama Maniss, 15 grams of Herba Taraxacis, 15 grams of Flos Loniceraes, 10 grams of Fructus Forsythiaes, 8 grams of Rhizoma Paridis, 10 grams, the Radix Rehmanniae, 20 grams of Radix Isatidis, 15 grams of Herba Lophatheris, 12 grams, Jiaoshan Hill branch, 8 grams of Radix Polygalaes, 10 grams of Radix Angelicae Sinensis, 12 grams of unpeeled CORTEX MOUTANs, 10 grams of Olibanums, 10 grams of Myrrhas, 10 grams of Radix Cirsii Japonicis, 10 grams of Herba Cirsiis, 7 grams, Radix Glycyrrhizae.Publication No. CN 102579774 A(application numbers 201210064652.2) Chinese invention patent a kind of Chinese medicine composition that is used for the treatment of the tuberculosis of cervical lymph nodes is disclosed, it is characterized in that being formed by the raw material of Chinese medicine of following weight portion: Spica Prunellae 25-35, Radix Ranunculi Ternati 25-35, Concha Ostreae 25-35, Radix Salviae Miltiorrhizae 10-20, Thallus Laminariae (Thallus Eckloniae) 10-20, Sargassum 10-20, Flos Lonicerae 5-15, Herba Taraxaci 5-15, Flos Chrysanthemi Indici flower 5-15, Radix Bupleuri 5-15, Radix Angelicae Sinensis 5-15, Radix Paeoniae Alba 5-15, Rhizoma Pinelliae 5-15, Pericarpium Citri Reticulatae 5-15, Rhizoma Cyperi 5-15, Radix Scutellariae 5-15, Eupatorium formosanum Hayata. 3-9, Herba Houttuyniae 3-9, Bullbus Allii nipponici 3-9, Herba Hyperici 3-9, Radix Semiaquilegiae 1-5, Herba Solani Lyrati 1-5.Publication number CN 101259216 A(application numbers 200810104561.0) Chinese invention patent disclose one and treated scrofulous Chinese medicine composition, the weight portion of its constitutive material is: Radix Aucklandiae 10-20 part, Radix Tylophorae arenicolae 5-10 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 part, Carapax Trionycis 5-10 part, Herba Phylae Samentosea 15-25 part, Fructus Forsythiae 10-15 part, Gekko Swinhonis 10-20 part, Sargassum 10-15 part, Thallus Laminariae (Thallus Eckloniae) 15-25 part, Scorpio 5-10 part, Concha Ostreae 20-30 part, Spica Prunellae 10-20 part, Radix Pulsatillae 15-25 part.

In a word, Chinese medicine is being obtained good curative effect aspect treatment primary disease at present.The phthisical medicine treatment of the multiplex treatment of doctor trained in Western medicine lymphoid tuberculosis, effect is all undesirable, simultaneously also larger to liver, renal function.Operative treatment easily recurs, therefore operative treatment and western medicine and medical practitioners treatment all can not reach desirable effect.Chinese medicine is being obtained good curative effect aspect treatment primary disease.

Summary of the invention

For the deficiencies in the prior art, the object of this invention is to provide that one is prepared simply, taking convenience, the agent of portable lymphoid tuberculosis promoting flow of QI and blood and preparation method thereof.This curative effect of medicine is definite and have no side effect.

Technical scheme of the present invention is:

The agent of lymphoid tuberculosis promoting flow of QI and blood, is prepared from by following bulk drugs, is weight portion: Fructus Gleditsia veneer 5-12 part; Flos Chrysanthemi Indici 6-15 part; Radix Platycodonis 3-9 part; Stachys geobombycis C. Y. Wu 5-15 part; Radix Scutellariae 6-10 part; Rhizoma et Radix smilacis ocreatae 4-8 part; Herba Erigerontis Annui 6-9 part; Radix Polygoni Multiflori 6-15 part; Dendrobium jenkinsii Wall ex Lindl． 18-32 part; Spica Prunellae 15-25 part; Fructus Forsythiae 6-12 part; JIANGSHI 5-12 part; Thallus Laminariae (Thallus Eckloniae) 6-15 part.

In preferred scheme, Fructus Gleditsia veneer 7-10 part; Flos Chrysanthemi Indici 8-13 part; Radix Platycodonis 4-8 part; Stachys geobombycis C. Y. Wu 8-12 part; Radix Scutellariae 7-9 part; Rhizoma et Radix smilacis ocreatae 5-7 part; Herba Erigerontis Annui 7-8 part; Radix Polygoni Multiflori 9-12 part; Dendrobium jenkinsii Wall ex Lindl． 23-27 part; Spica Prunellae 18-22 part; Fructus Forsythiae 7-11 part; JIANGSHI 7-10 part; Thallus Laminariae (Thallus Eckloniae) 9-12 part.

Be more preferably 8.5 parts of Fructus Gleditsia veneer; 10.5 parts of Flos Chrysanthemi Indicis; 6 parts of Radix Platycodoniss; 10 parts of Stachys geobombycis C. Y. Wu; 8 parts of Radix Scutellariaes; 6 parts of Rhizoma et Radix smilacis ocreataes; 7.5 parts of Herba Erigerontis Annuis; 10.5 parts of Radix Polygoni Multiflori; 25 parts of Dendrobium jenkinsii Wall ex Lindl．; 20 parts of Spica Prunellaes; 9 parts of Fructus Forsythiaes; 8.5 parts of JIANGSHI; 10.5 parts of Thallus Laminariae (Thallus Eckloniae)s.

The present invention also provides the preparation method of aforementioned medicament being made to pharmaceutically acceptable decoction, powder, pill and thick paste agent.

The preparation method of described decoction is:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 100-140 mesh sieve (the preferred 110-130 of mistake mesh sieve), obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 120-160 mesh sieve (the preferred 130-150 of mistake mesh sieve), obtains JIANGSHI powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Thallus Laminariae (Thallus Eckloniae) is shredded, is washed away salt water, together be placed in crock with Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, the pure water and the yellow wine (ratio of pure water and yellow wine is 5:1) that add 4-6 doubly to measure, soak 3-6 hour (preferably soaking 4-5 hour), big fire decocts 2-4 hour (preferably decocting 2.5-3.5 hour), pressure filtration while hot, obtains decocting liquid;

(4) fine powder 1 and fine powder 2 are joined in above-mentioned decocting liquid, stir while hot, 120 DEG C of sterilizings, encapsulation, to obtain final product.

The preparation method of above-mentioned lymphoid tuberculosis promoting flow of QI and blood decoction, preferred scheme is that in step (4), sterilization time is 2-4 hour (preferred sterilization time is 2.5-3.5 hour, and the sterilization time being more preferably is 3 hours).

The preparation method of described powder is:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 100-130 mesh sieve (the preferred 110-120 of mistake mesh sieve), obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 110-140 mesh sieve (the preferred 120-130 of mistake mesh sieve), obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae are cleaned, dried, Thallus Laminariae (Thallus Eckloniae) shreds, washes away salt water, dries; Together grind into powder, cross 80-120 mesh sieve (the preferred 90-110 of mistake mesh sieve), obtain fine powder 3;

(4) by fine powder 1, fine powder 2 and fine powder 3 mix homogeneously, dry sterilization, subpackage, every bag of 8g, obtains powder.

The preparation method of described pill is:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 100-130 mesh sieve (the preferred 110-120 of mistake mesh sieve), obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 110-140 mesh sieve (the preferred 120-130 of mistake mesh sieve), obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae are cleaned, dried, Thallus Laminariae (Thallus Eckloniae) shreds, washes away salt water, dries; Together grind into powder, cross 80-120 mesh sieve (the preferred 90-110 of mistake mesh sieve), obtain fine powder 3;

(4) by fine powder 1, fine powder 2 and fine powder 3 mix homogeneously, with water pill, obtain pill.

The preparation method of described thick paste agent is:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 110-160 mesh sieve (the preferred 120-140 of mistake mesh sieve), obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 120-180 mesh sieve (the preferred 140-160 of mistake mesh sieve), obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Thallus Laminariae (Thallus Eckloniae) is shredded, is washed away salt water, together be placed in crock with Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, the pure water and the yellow wine (ratio of pure water and yellow wine is 5:1) that add 4-6 doubly to measure, soak 3-6 hour (preferably soaking 4-5 hour), big fire decocts 2-4 hour (preferably decocting 2.5-3.5 hour), pressure filtration while hot, obtains decocting liquid;

(4) above-mentioned gained decocting liquid is carried out to distilling under reduced pressure, be condensed into paste; Then add fine powder 1 and fine powder 2, stir, 120 DEG C of sterilizings, obtain thick paste agent.

The application of medicament described in the present invention also provides in the time of preparation lymphoid tuberculosis promoting flow of QI and blood medicine.

The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:

Fructus Gleditsia veneer: base is former: be peel of stem and the root bark of pulse family Gleditsia plant Fructus Gleditsia.Nature and flavor: pungent, warm, nontoxic.Function cures mainly: detoxicating and resolving stagnation of pathogens, wind dispelling insecticide.Cure mainly lymphoid tuberculosis, innominate toxic swelling, rheumatic ostalgia, scabies moss, malignant boil.

JIANGSHI: base is former: be calcareous concretion in loess formation or air slaking red soil floor.Composition: be mainly calcium carbonate.Still contain the elements such as fluorine, iodine, silicon, ferrum, zinc-copper, manganese, cobalt, vanadium, tungsten, selenium, molybdenum.The property of medicine: " Newly Revised Canon of Materia Medica ": " salty in the mouth, cold, nontoxic." function cures mainly: clearing heat, releasing toxin, removing swelling.Cure mainly furuncle carbuncle, acute mastitis, scrofula, carbuncle on the back malignant boil, smallpox.

Flos Chrysanthemi Indici: base is former: be root or the herb of Compositae Dendranthema Flos Chrysanthemi Indici or lavandulaleaf dendranthema herb.The property of medicine: bitter, acrid, cold.Return liver, heart channel.Function cures mainly: heat-clearing and toxic substances removing, improving eyesight.Cure mainly flu, dysentery, carbuncle, furuncle, conjunctival congestion and swelling pain, dizzy, scrofula, eczema.

Thallus Laminariae (Thallus Eckloniae): base is former: be the thallus of Laminariaceae (Laminariophyceae) Larminaria plant Thallus Laminariae (Thallus Eckloniae) and the black Thallus Laminariae (Thallus Eckloniae) of Alariaceae laminaria, undaria plant Thallus Laminariae.Composition: 1. Thallus Laminariae (Thallus Eckloniae), containing compound of polysaccharide, mainly contains three kinds: one is alginate, is alginic acid and sodium thereof, potassium, ammonium, calcium salt etc.; Secondly be that rock algae is according to polysaccharide; Moreover be laminarin etc.2. black Thallus Laminariae (Thallus Eckloniae) contains alginic acid and sodium salt thereof, laminarin, mannitol, vitamin, halogenide, sulfate, phosphate, iodine and other trace element lamps.3. the full algae of Thallus Laminariae, containing compound of polysaccharide, is mainly alginic acid, laminarin and lipopolysaccharide etc.The property of medicine: salty, cold.Gui Jing: return liver, stomach, kidney channel.Function cures mainly: softening and eliminating sputum, inducing diuresis to remove edema.Cure mainly goiter, scrofula, swelling of the scrotum, the cancer of the esophagus, beriberi edema.

Stachys geobombycis C. Y. Wu: base is former: be rhizome or the herb of Labiatae betony Stachys geobombycis C. Y. Wu.Chemical composition: herb is containing stachydrine, choline, stachyose.Nature and flavor: 1. principle of Correct Diet: " sweet, flat, nontoxic." 2. " Guizhou medical herbs ": " property is flat, and sweet in the mouth is micro-pungent." return through: return lung, liver, spleen channel.Function cures mainly: kidney tonifying lung moistening, nourishing YIN and supplementing blood, clearing heat and relieving fidgetness.For pulmonary tuberculosis cough, deficiency of the lung asthma, spits blood, night sweat, anemia, infantile malnutrition.

Dendrobium jenkinsii Wall ex Lindl．: be the stem of dicotyledon medicine orchid Dendrobium jenkinsii Wall ex Lindl． (shrimp ridge Herba Dendrobii).With all herbal medicine.Nature and flavor: sweet, light, flat.Gui Jing: lung, stomach two warps.Effect: nourishing YIN and clearing away heat, promoting the production of body fluid to quench thirst, nourishing the lung to arrest cough.Cure mainly: for laryngopharynx swelling and pain, oral erosion, quench one's thirst, xerostomia, thirsty etc., cough, expectoration, asthma, the deficiency of YIN etc.

Radix Scutellariae: base is former: this product is the dry root of labiate Radix Scutellariae.Character: this product is conical.Surface brown color or buff, have sparse excipuliform radicula trace. and top is more coarse, has vertical wrinkle or the irregular reticulate pattern of distortion, and rift grain and scabriculous are arranged at bottom.Nature and flavor: hardship, cold.Gui Jing: return lung, gallbladder, spleen, large intestine, small intestine meridian.Effect: heat clearing and damp drying, rush down people's removing toxic substances, hemostasis, antiabortive.Cure mainly: for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.

Rhizoma et Radix smilacis ocreatae: base is former: be the rhizome of dicotyledon medicine liliaceous plant Rhizoma et Radix smilacis ocreatae.Chemical composition: rhizome is containing steroid saponin, tannin, resin and much starch.Nature and flavor: hardship, cold.Gui Jing: GUIXIN warp.Effect: clearing away heat-damp and promoting diuresis.Cure mainly: available dispelling the wind and dampness pathogens arthralgia pain, the person that is especially suitable for damp-heat syndrome.

Herba Erigerontis Annui: base is former: be herb and the root of chrysanthemum kind of plant Herba Erigerontis Annui.Nature and flavor: " Zhejiang conventional medical herbs among the people ": " property is flat, lightly seasoned." function cures mainly: heat-clearing and toxic substances removing is aid digestion.Control dyspepsia, enteritis, diarrhea, infectious hepatitis, lymphadenitis, hematuria.Pharmacological action: the water extract after stem, leaf wash with petroleum ether, ether, chloroform, has hypoglycemic activity.

Radix Platycodonis: nature and flavor: bitter, pungent, flat.Gui Jing: return lung meridian.Effect: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.Cure mainly: for cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.

Radix Polygoni Multiflori: base is former: the dried root that this product is polygonum multiflorum thunb.Secondly chemical analysis: root and rhizome, containing Anthraquinones, are mainly chrysophanol and emodin is physcione and the chrysophanic acid anthrone etc. (processing later without chrysophanic acid) of chrysophanic acid, trace.Nature and flavor: bitter, sweet, puckery. temperature.Gui Jing: return liver, the heart, kidney channel.Effect: removing toxic substances, disappear de-, loosening bowel to relieve constipation.Cure mainly: for scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; Hyperlipidemia.Pharmacological action: 1. effect for reducing blood fat; 2. hypoglycemic activity; 3. antibacterial action.

Fructus Forsythiae: base is former: this product is the dry fruit of Oleaceae plants Fructus Forsythiae.Character: this product is long avette to avette, slightly flat.There is the fleck of irregular vertical wrinkle and most projections on surface, and respectively there is 1 obvious longitudinal furrow on two sides.The sharp point in top.Nature and flavor: hardship, is slightly cold.Gui Jing: return lung, the heart, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Cure mainly: for carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease is from the beginning of, warm joining the army, high hot excessive thirst, coma is sent out speckle, pyretic stranguria urine retention.

Spica Prunellae: base is former: this product is the dry fruit ear of labiate Spica Prunellae.Chemical analysis: herb is containing triterpenoid saponin, its glycoside unit is oleanolic acid, still containing free oleanolic acid, ursolic acid, globulariacitrin, hyperin, cis-caffeic acid, trans-caffeic acid, vitamin B1, vitamin C, vitamin K, carotene, resin, amaroid, tannin, volatile oil, alkaloid, water soluble salt (approximately 3.5%, wherein approximately 63% is potassium chloride) etc.Nature and flavor: pungent, bitter, cold.Gui Jing: return liver, gallbladder meridian.Effect: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.Cure mainly: for conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.Pharmacological action: 1. hypotensive effect; 2. antibacterial action.

Drug prescription science provided by the invention, the preparation method of various dosage forms is simple, products obtained therefrom taking convenience, is easy to carry.In addition, excellent results of the present invention also shows:

1,selected materials is all Chinese medicine material, without any side effects;

2,this prescription compatibility is accurate, and treatment lymphoid tuberculosis curative effect is fast, and short treating period, has the effects such as promoting flow of QI and blood, blood stasis-eliminating and stagnation-dissipating, promoting the flow of QI in the collateral by warming the meridian;

3,the drug action of this prescription is lasting, can calm down sign, can eliminate again old complaint, reaches treating both the principal and secondary aspects of a disease object;

4,medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.

embodiment 1the agent of lymphoid tuberculosis promoting flow of QI and blood, is prepared from by following bulk drugs: Fructus Gleditsia veneer 5g, Flos Chrysanthemi Indici 6-15 part, Radix Platycodonis 3g, Stachys geobombycis C. Y. Wu 5g, Radix Scutellariae 6g, Rhizoma et Radix smilacis ocreatae 4g, Herba Erigerontis Annui 6g, Radix Polygoni Multiflori 6g, Dendrobium jenkinsii Wall ex Lindl． 18g, Spica Prunellae 15g, Fructus Forsythiae 6g, JIANGSHI 5g, Thallus Laminariae (Thallus Eckloniae) 6g.

The preparation method of above-mentioned lymphoid tuberculosis promoting flow of QI and blood decoction:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 100-140 mesh sieve, obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 120-160 mesh sieve, obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Thallus Laminariae (Thallus Eckloniae) is shredded, is washed away salt water, together be placed in crock with Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, the pure water and the yellow wine (ratio of pure water and yellow wine is 5:1) that add 4-6 doubly to measure, soak 3-6 hour, big fire decocts 2-4 hour, pressure filtration while hot, obtains decocting liquid;

(4) fine powder 1 and fine powder 2 are joined in above-mentioned decocting liquid, stir while hot, 120 DEG C of sterilizings 2 hours, encapsulation, to obtain final product.

The instructions of taking of decoction of the present invention: decoction is 5 days courses for the treatment of, takes twice (warm) every day, each 80m1-120m1.

Model case: Pan xx, man, 17 years old, student.Patient right side cervical region has a shape as the swollen thing of plum pit, and matter is hard, and what push away is motionless, presses pain, red tongue, few tongue, thready and rapid pulse.Companion body matter is become thin, lassitude, and appetite is not good enough, flushed cheeks, hectic fever, five heart heatings.Check: erythrocyte sedimentation rate 35mm/ hour, lymphocyte 60%.Be diagnosed as QIXUELIANGXU type lymphoid tuberculosis.

Take the present embodiment gained lymphoid tuberculosis promoting flow of QI and blood decoction, take every day twice (warm), each 80m1-120m1,5 days courses for the treatment of.Take four courses for the treatment of, swollen thing disappears gradually, and hectic fever is decorporated, and the amount of receiving increases, spirit can, other symptoms are improved greatly, adhere to again taking three courses for the treatment of, it is normal that every sign is recovered, patient's recovery from illness, without recurrence.

embodiment 2the agent of lymphoid tuberculosis promoting flow of QI and blood, is prepared from by following bulk drugs: Fructus Gleditsia veneer 12g, Flos Chrysanthemi Indici 15g, Radix Platycodonis 9g, Stachys geobombycis C. Y. Wu 15g, Radix Scutellariae 10g, Rhizoma et Radix smilacis ocreatae 8g, Herba Erigerontis Annui 9g, Radix Polygoni Multiflori 15g, Dendrobium jenkinsii Wall ex Lindl． 32g, Spica Prunellae 25g, Fructus Forsythiae 12g, JIANGSHI 12g, Thallus Laminariae (Thallus Eckloniae) 15g.

The preparation method of above-mentioned lymphoid tuberculosis promoting flow of QI and blood powder:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 110-120 mesh sieve, obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 120-130 mesh sieve, obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae are cleaned, dried, Thallus Laminariae (Thallus Eckloniae) shreds, washes away salt water, dries; Together grind into powder, cross 90-110 mesh sieve, obtain fine powder 3;

(4) by fine powder 1, fine powder 2 and fine powder 3 mix homogeneously, dry sterilization, subpackage, every bag of 8g, obtains powder.

The instructions of taking of powder of the present invention: powder is 5 days courses for the treatment of, each 1 bag, takes every day twice (warm).

Model case: money xx, female, 27 years old, people from Jining.Patient's readme: after left ear, cervical region has a lump the year before, sharp ache forms pustule gradually, has hydrops, goes examination in hospital to be diagnosed as lymphoid tuberculosis.By surgical operation therapy, the state of an illness is controlled.Find in the recent period to occur again lump, disease relapse in same position.Then consider Chinese traditional treatment.Find after diagnosing: Zuo Erchu has obvious perilymphadenitis, and the lymph node of enlargement and surrounding tissue and skin adhesion are mobile restricted, pain and tenderness strengthen, and central part starts cheesy necrosis.Patient is with low grade fever, night sweat, the symptom such as weak.Be diagnosed as infiltrative type lymphoid tuberculosis.

Take the present embodiment gained lymphoid tuberculosis promoting flow of QI and blood powder, each 1 bag, take twice (warm) 5 days courses for the treatment of every day.Take one month, lymphoid tuberculosis is obviously improved, and symptom alleviates, and without low grade fever, spirit can; Continue to take 4 courses for the treatment of, lump disappears, and it is normal that every sign is recovered.When patient takes, do not occur any discomfort, patient's self-induction symptom is controlled; After half a year, pay a return visit, without recurrence.

embodiment 3the agent of lymphoid tuberculosis promoting flow of QI and blood, is prepared from by following bulk drugs: Fructus Gleditsia veneer 7g, Flos Chrysanthemi Indici 8g, Radix Platycodonis 4g, Stachys geobombycis C. Y. Wu 8g, Radix Scutellariae 7g, Rhizoma et Radix smilacis ocreatae 5g, Herba Erigerontis Annui 7g, Radix Polygoni Multiflori 9g, Dendrobium jenkinsii Wall ex Lindl． 23g, Spica Prunellae 18g, Fructus Forsythiae 7g, JIANGSHI 7g, Thallus Laminariae (Thallus Eckloniae) 9g.

The preparation method of above-mentioned lymphoid tuberculosis promoting flow of QI and blood pill:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 110-120 mesh sieve, obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 120-130 mesh sieve, obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae are cleaned, dried, Thallus Laminariae (Thallus Eckloniae) shreds, washes away salt water, dries; Together grind into powder, cross 90-110 mesh sieve, obtain fine powder 3;

(4) by fine powder 1, fine powder 2 and fine powder 3 mix homogeneously, with water pill, obtain pill.

The using method of pill of the present invention is: adopt every day three times, and each 2-3 ball (approximately 3 grams/ball of drug loading), with warm water delivery service, 5 days courses for the treatment of.

Model case: all xx, man., there is a lymph enlargement in October, 2010 on the right clavicle of Mr. Zhou, when beginning, lump is harder, presses without pain, thinks it is inflammation, so take some conventional anti-inflammation drugs.Lump was softening gradually afterwards, formed abscess, and surrounding skin is blue, attenuation, and abscess voluntarily ulceration forms again ulcer.Patient once took western medicine, had just started that sb.'s illness took a favorable turn, but soon, disease relapse, lump increases.Meanwhile, patient is with cough, the diseases such as night sweat.Be diagnosed as ulcer type lymphoid tuberculosis.

Take the present embodiment gained lymphoid tuberculosis promoting flow of QI and blood pill, adopt every day three times, each 2-3 ball, with warm water delivery service, 5 days courses for the treatment of.Take two weeks, ulcer is controlled, and abscess improves, and cough alleviates, and night sweat disappears.Continue to take 4 courses for the treatment of, the every symptom of patient is all effectively alleviated, and it is normal that surrounding skin recovers, and lump disappears, and the mental status is good.Patient adheres to taking medicine, and patient's recovery from illness after two months, follows up a case by regular visits to without recurrence.

embodiment 4the agent of lymphoid tuberculosis promoting flow of QI and blood, is prepared from by following bulk drugs: 10 parts of Fructus Gleditsia veneer, 13 parts of Flos Chrysanthemi Indicis, 8 parts of Radix Platycodoniss, 12 parts of Stachys geobombycis C. Y. Wu, 9 parts of Radix Scutellariaes, 7 parts of Rhizoma et Radix smilacis ocreataes, 8 parts of Herba Erigerontis Annuis, 12 parts of Radix Polygoni Multiflori, 27 parts of Dendrobium jenkinsii Wall ex Lindl．, 22 parts of Spica Prunellaes, 11 parts of Fructus Forsythiaes, 10 parts of JIANGSHI, 12 parts of Thallus Laminariae (Thallus Eckloniae)s.

The preparation method of above-mentioned lymphoid tuberculosis promoting flow of QI and blood thick paste agent:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 120-140 mesh sieve, obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 140-160 mesh sieve, obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Thallus Laminariae (Thallus Eckloniae) is shredded, is washed away salt water, together be placed in crock with Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, the pure water and the yellow wine (ratio of pure water and yellow wine is 5:1) that add 4-6 doubly to measure, soak 4-5 hour, big fire decocts 2.5-3.5 hour, pressure filtration while hot, obtains decocting liquid;

(4) above-mentioned gained decocting liquid is carried out to distilling under reduced pressure, be condensed into paste; Then add fine powder 1 and fine powder 2, stir, 120 DEG C of sterilizings, obtain thick paste agent.

The instructions of taking of thick paste agent of the present invention: get a soupspoon soft extract, be placed in cup, take after mixing it with water with boiled water, a course for the treatment of of twice, 5 day every day.

Model case: Lee, female, 27 years old, company clerk.Readme: patient's auris dextra below pruritus of suddenly feeling before three months, scratching finds that there is a Semen Juglandis size lump, and matter is hard, rear lump increases, and with skin adhesion, forms pustule, Dressed plaster treatment, symptom increases the weight of on the contrary, checks and finds: the open sore part is suppurated, and pus color is clear and rare, accompany worn-out cotton wadding for quilt sample material, patient's emaciated physique, tired mind, light red tongue, thin fur, thready pulse.Be diagnosed as lymphoid tuberculosis (deficiency of both QI and blood).

Take the agent of the present embodiment gained lymphoid tuberculosis promoting flow of QI and blood thick paste, while taking, get a soupspoon soft extract, be placed in cup, take after mixing it with water with boiled water, a course for the treatment of of twice, 5 day every day.Take one month, patient's open sore part heals gradually, and lump dwindles and slowly decorporates, and the mental status is good, and stable disease can be controlled.Take again 1 month, the every glucose recovery of patient is normal, and lump disappears not multiple.Following the service is consolidated 2 courses for the treatment of, and patient's recovery from illness, paid a return visit without recurrence after half a year.

embodiment 5the agent of lymphoid tuberculosis promoting flow of QI and blood, is prepared from by following bulk drugs: Fructus Gleditsia veneer 8.5g, Flos Chrysanthemi Indici 10.5g, Radix Platycodonis 6g, Stachys geobombycis C. Y. Wu 10g, Radix Scutellariae 8g, Rhizoma et Radix smilacis ocreatae 6g, Herba Erigerontis Annui 7.5g, Radix Polygoni Multiflori 10.5g, Dendrobium jenkinsii Wall ex Lindl． 25g, Spica Prunellae 20g, Fructus Forsythiae 9g, JIANGSHI 8.5g, Thallus Laminariae (Thallus Eckloniae) 10.5g.

The preparation method of above-mentioned lymphoid tuberculosis promoting flow of QI and blood decoction:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 110-130 mesh sieve, obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 130-150 mesh sieve, obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Thallus Laminariae (Thallus Eckloniae) is shredded, is washed away salt water, together be placed in crock with Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, the pure water and the yellow wine (ratio of pure water and yellow wine is 5:1) that add 4-6 doubly to measure, soak 4-5 hour, big fire decocts 2.5-3.5 hour, pressure filtration while hot, obtains decocting liquid;

(4) fine powder 1 and fine powder 2 are joined in above-mentioned decocting liquid, stir while hot, 120 DEG C of sterilizings 3 hours, encapsulation, to obtain final product.

The instructions of taking of decoction of the present invention: decoction is 5 days courses for the treatment of, takes twice (warm) every day, each 80m1-120m1.

test example:for showing the therapeutic effect of lymphoid tuberculosis promoting flow of QI and blood of the present invention agent, 253 routine cases have been carried out to clinical observation, existing report is as follows:

1 data and method:

1.1 diagnostic criterias: according to patient's medical history, symptom, sign, x-ray inspection and tuberculin experimental result, and lymphadenectasis, adhesion, tenderness even can form sinus tract after ulceration, moves under water with skin bottom, prolongedly do not heal.Be diagnosed as QIXUELIANGXU type lymphoid tuberculosis.

1.2 treatment targets: in March, 2009-2011 year June, choose 253 routine lymphoid tuberculosis patients according to above standard in 4 hospitals.Wherein women's 136 examples, male's 117 examples; Age 18-63 year.All patients are divided into treatment group 149 example and matched group 104 examples at random, and two groups of patients are learning processing by statistics aspect sex, age, the course of disease, and no statistical significance (P > 0.05), has comparability.

1.3 Therapeutic Method: treatment group is taken the present embodiment 5 gained lymphoid tuberculosis motives decoction of invigorating blood circulation, instructions of taking is to take (warm), each 80m1-120m1,5 days courses for the treatment of every day twice.Matched group is taken the scrofulous conventional medicine of other treatment (as JIEHELING, rifampicin, tuberculosis cream etc.).Observation of curative effect one month.

1.4 efficacy assessment standards: cure: the tuberosity of enlargement all disappears or narrows down to below 0.05 cubic centimetre, and hardening, or the healing of diabrosis skin ulcer face; Effective: the tuberosity of enlargement disappears more than 2/3, or diabrosis skin ulcer face heals more than 2/3; Take a turn for the better: the state of an illness alleviates, but does not reach effective; Invalid: without improving or worsening.

1.5 therapeutic outcome contrasts

Clinical efficacy comparison after two groups of patient treatments, as shown in table 1.

 

Clinical efficacy comparison after table 1 liang group patient treatment

Therapeutic effect: cure 113 examples (75.8%), effective 20 examples (13.4%), 14 examples that take a turn for the better (9.5%), invalid 2 examples (1.3%), total effective rate 98.7%.Successful is better than matched group.

 

Treatment group and matched group clinical symptom remission rate are as shown in table 2.

 

Table 2: treatment group and matched group clinical symptom remission rate

The present invention selects Radix Polygoni Multiflori, Dendrobium jenkinsii Wall ex Lindl．, Fructus Forsythiae, Thallus Laminariae (Thallus Eckloniae) etc. to carry out compatibility, makes after these drug regimens to produce synergism, can more effectively treat lymphoid tuberculosis.Fructus Gleditsia veneer detoxicating and resolving stagnation of pathogens in side, wind dispelling insecticide; JIANGSHI, Flos Chrysanthemi Indici clearing heat, releasing toxin, removing swelling; Stachys geobombycis C. Y. Wu nourishing YIN and supplementing blood, clearing heat and relieving fidgetness; Radix Scutellariae, Rhizoma et Radix smilacis ocreatae solution stagnation of liver-QI, nourishing the liver blood, treatment congestion of the liver deficient syndrome.All medicines share, and invigorate blood circulation and can yin nourishing, and blood stasis dispelling and just not hindering, has one's ideas straightened out and the QI invigorating of holding concurrently, therefore can obtain good therapeutic effect.After patient takes 6 courses for the treatment of, total effective rate reaches 98.7%, and matched group is 78.8%, and treatment group is obviously better than matched group.

It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clearly disclosed or according to undoubted the obtaining of the written description of file, all should think the claimed scope of this patent.

Claims (10)

1. the agent of lymphoid tuberculosis promoting flow of QI and blood, is characterized in that, is prepared from by following bulk drugs, be weight portion: Fructus Gleditsia veneer 5-12 part, Flos Chrysanthemi Indici 6-15 part, Radix Platycodonis 3-9 part, Stachys geobombycis C. Y. Wu 5-15 part, Radix Scutellariae 6-10 part, Rhizoma et Radix smilacis ocreatae 4-8 part, Herba Erigerontis Annui 6-9 part, Radix Polygoni Multiflori 6-15 part, Dendrobium jenkinsii Wall ex Lindl． 18-32 part, Spica Prunellae 15-25 part, Fructus Forsythiae 6-12 part, JIANGSHI 5-12 part, Thallus Laminariae (Thallus Eckloniae) 6-15 part.

2. medicament as claimed in claim 1, is characterized in that, Fructus Gleditsia veneer 7-10 part, Flos Chrysanthemi Indici 8-13 part, Radix Platycodonis 4-8 part, Stachys geobombycis C. Y. Wu 8-12 part, Radix Scutellariae 7-9 part, Rhizoma et Radix smilacis ocreatae 5-7 part, Herba Erigerontis Annui 7-8 part, Radix Polygoni Multiflori 9-12 part, Dendrobium jenkinsii Wall ex Lindl． 23-27 part, Spica Prunellae 18-22 part, Fructus Forsythiae 7-11 part, JIANGSHI 7-10 part, Thallus Laminariae (Thallus Eckloniae) 9-12 part.

3. medicament as claimed in claim 1, is characterized in that, 8.5 parts of Fructus Gleditsia veneer, 10.5 parts of Flos Chrysanthemi Indicis, 6 parts of Radix Platycodoniss, 10 parts of Stachys geobombycis C. Y. Wu, 8 parts of Radix Scutellariaes, 6 parts of Rhizoma et Radix smilacis ocreataes, 7.5 parts of Herba Erigerontis Annuis, 10.5 parts of Radix Polygoni Multiflori, 25 parts of Dendrobium jenkinsii Wall ex Lindl．, 20 parts of Spica Prunellaes, 9 parts of Fructus Forsythiaes, 8.5 parts of JIANGSHI, 10.5 parts of Thallus Laminariae (Thallus Eckloniae)s.

4. the medicament as described in as arbitrary in claim 1-3, is characterized in that, this medicament is made to pharmaceutically acceptable decoction, powder, pill and thick paste agent.

5. medicament as claimed in claim 4, is characterized in that, the preparation method of described decoction is:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 100-140 mesh sieve (the preferred 110-130 of mistake mesh sieve), obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 120-160 mesh sieve (the preferred 130-150 of mistake mesh sieve), obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Thallus Laminariae (Thallus Eckloniae) is shredded, is washed away salt water, together be placed in crock with Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, the pure water and the yellow wine (ratio of pure water and yellow wine is 5:1) that add 4-6 doubly to measure, soak 3-6 hour (preferably soaking 4-5 hour), big fire decocts 2-4 hour (preferably decocting 2.5-3.5 hour), pressure filtration while hot, obtains decocting liquid;

(4) fine powder 1 and fine powder 2 are joined in above-mentioned decocting liquid, stir while hot, 120 DEG C of sterilizings, encapsulation, to obtain final product.

6. preparation method according to claim 5, is characterized in that, in step (4), sterilization time is 2-4 hour (preferred sterilization time is 2.5-3.5 hour, and the sterilization time being more preferably is 3 hours).

7. medicament as claimed in claim 4, is characterized in that, the preparation method of described powder is:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 100-130 mesh sieve (the preferred 110-120 of mistake mesh sieve), obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 110-140 mesh sieve (the preferred 120-130 of mistake mesh sieve), obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae are cleaned, dried, Thallus Laminariae (Thallus Eckloniae) shreds, washes away salt water, dries; Together grind into powder, cross 80-120 mesh sieve (the preferred 90-110 of mistake mesh sieve), obtain fine powder 3;

(4) by fine powder 1, fine powder 2 and fine powder 3 mix homogeneously, dry sterilization, subpackage, every bag of 8g, obtains powder.

8. medicament as claimed in claim 4, is characterized in that, the preparation method of described pill is:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 100-130 mesh sieve (the preferred 110-120 of mistake mesh sieve), obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 110-140 mesh sieve (the preferred 120-130 of mistake mesh sieve), obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae are cleaned, dried, Thallus Laminariae (Thallus Eckloniae) shreds, washes away salt water, dries; Together grind into powder, cross 80-120 mesh sieve (the preferred 90-110 of mistake mesh sieve), obtain fine powder 3;

(4) by fine powder 1, fine powder 2 and fine powder 3 mix homogeneously, with water pill, obtain pill.

9. medicament as claimed in claim 4, is characterized in that, the preparation method of described thick paste agent is:

(1) get Radix Polygoni Multiflori, Fructus Gleditsia veneer is poured in basin, mixes thoroughly with decoction of black soybean and yellow wine, puts in tank, sealing, sits stewing out of water to juice in kettle and exhausts, and takes out, and dries, and grinds into powder, crosses 110-160 mesh sieve (the preferred 120-140 of mistake mesh sieve), obtains fine powder 1;

(2) JIANGSHI is put in crock, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry, levigation, crosses 120-180 mesh sieve (the preferred 140-160 of mistake mesh sieve), obtains fine powder; Stachys geobombycis C. Y. Wu is cleaned, cooks, dries, is ground into powder, sieves, and mixes with JIANGSHI powder, obtains fine powder 2;

(3) Thallus Laminariae (Thallus Eckloniae) is shredded, is washed away salt water, together be placed in crock with Flos Chrysanthemi Indici, Radix Platycodonis, Radix Scutellariae, Rhizoma et Radix smilacis ocreatae, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, the pure water and the yellow wine (ratio of pure water and yellow wine is 5:1) that add 4-6 doubly to measure, soak 3-6 hour (preferably soaking 4-5 hour), big fire decocts 2-4 hour (preferably decocting 2.5-3.5 hour), pressure filtration while hot, obtains decocting liquid;

(4) above-mentioned gained decocting liquid is carried out to distilling under reduced pressure, be condensed into paste; Then add fine powder 1 and fine powder 2, stir, 120 DEG C of sterilizings, obtain thick paste agent.

10. the application of the medicament as described in as arbitrary in claim 1-3 in the time of preparation lymphoid tuberculosis promoting flow of QI and blood medicine.