CN104189611A - Traditional Chinese medicine composition for treating hand-foot-and-mouth disease - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating the hand-foot-and-mouth disease. The traditional Chinese medicine composition comprises the following components: herba agastachis, radices sileris, red paeony root, amur corktree bark, fritillaria thun-bergli, coptis chinensis, dendrobium, pinellia ternata, radix angelicae, junci medulla, rhizoma coptidis, forsythia, folium phyllostachys, periostracum cicada, mentha haplocalyx and radix isatidis. The traditional Chinese medicine composition is obtained after the compatibility of a clinical prescription for many times and has the efficacies of clearing away heat and detoxifying, invigorating mind and clearing away lung heat, and clearing away heat and carrying out spleen diarrhea; after being taken, the traditional Chinese medicine composition reaches lesions to quickly take effects, externally relieve evil on the muscle surface and internally eliminate dampness turbidity, so that the interior-exterior pathogens are eliminated, and the pathogenesis is determined, thereby the purposes of regulating the functions of internal organs, balancing yin and yang, and strengthening body resistance and eliminating evil are achieved; fever, headache, stomatalgia, pharyngalgia, rash, anabrosis, anorexia and other symptoms can be completely relieved; through comprehensive treatment, the body immunity is improved, and the hand-foot-and-mouth disease is cured.

Description

A kind of Chinese medicine composition for the treatment of hand-foot-mouth disease

Technical field

The present invention relates to the field of Chinese medicines, relate to specifically a kind of Chinese medicine composition for the treatment of hand-foot-mouth disease.

Background technology

Hand-foot-mouth disease is the infectious disease being caused by enterovirus, and the multiple preschooler of being born in, can cause erythra, the ulcer at the positions such as heating and hands, foot, oral cavity, and indivedual patients can cause the complication such as myocarditis, pulmonary edema, AME.

When hand-foot-mouth disease occurs, sick child is often with heating onset, and its temperature not etc., does not also have not heating person, but with the low grade fever person half of approximately putting in the majority, and often with symptoms such as sialorrhea, watery nasal discharge, stomatalgia, pharyngalgia and anorexia.It is clinical that to take oral cavity, brothers' herpes be principal character.Herpes of mouth sees tongue, buccal mucosa, hard palate, lip, pharynx and tonsil, and ulceration forms ulcer rapidly.Erythra is more common between brothers' far-end, Fingers, and heel edge and first week, palm and the sufficient sole of the foot are also common, and lower limb and buttocks can be the pimple sample erythra of dense distribution, from the beginning of being maculopapule, after change herpes into, circular or oval, compared with chickenpox erythra, be little, quality is harder, has blush around.

In recent years, hand-foot-mouth disease morbidity has the trend of increasing, often cause localized epidemics, western medical treatment hand-foot-mouth disease there is no desirable special effect medicine therapeutic at present, and Western medicine because of curative effect individual variation large, side effect is obvious, more the easy reason such as recurrence after, makes vast infant and the head of a family more be ready to select Chinese medicine, and Chinese medicine is when treating hand-foot-mouth disease disease, take into account to have and focus on to regulate infant whole body equilibrium between yin and yang and function, improve the feature of infant health and have much characteristic comprehensively, and be difficult for recurrence more afterwards.

Summary of the invention

The problem to be solved in the present invention is for above problem, and a kind of Chinese medicine composition for the treatment of hand-foot-mouth disease of evident in efficacy, safe and reliable, no dependence is provided.

For addressing the above problem, the technical solution adopted in the present invention is:

A Chinese medicine composition for the treatment of hand-foot-mouth disease, is characterized in that: described Chinese medicine composition is comprised of following component:

Herba Pogostemonis 10-20 gram, Radix Saposhnikoviae 10-20 gram, Radix Paeoniae Rubra 10-20 gram, Cortex Phellodendri 10-20 gram, Bulbus Fritillariae Uninbracteatae 10-20 gram, Rhizoma Coptidis 10-20 gram, Herba Dendrobii 10-20 gram, Rhizoma Pinelliae 8-12 gram, Radix Angelicae Dahuricae 8-12 gram, Medulla Junci 8-12 gram, Rhizoma Coptidis 8-12 gram, Fructus Forsythiae 8-12 gram, Folium Bambusae 8-12 gram, Periostracum Cicadae 8-12 gram, Herba Menthae 10-20 gram, Radix Isatidis 8-12 gram.

As a kind of prioritization scheme:

Described Chinese medicine composition is comprised of following component:

10 grams of Herba Pogostemoniss, 10 grams of Radix Saposhnikoviaes, 10 grams of Radix Paeoniae Rubra, 10 grams of Cortex Phellodendris, 10 grams of Bulbus Fritillariae Uninbracteataes, 10 grams of Rhizoma Coptidis, 10 grams of Herba Dendrobiis, 8 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Angelicae Dahuricae, 8 grams of Medulla Juncies, 8 grams of Rhizoma Coptidis, 8 grams of Fructus Forsythiaes, 8 grams, Folium Bambusae, 8 grams of Periostracum Cicadaes, 10 grams of Herba Menthaes, 8 grams of Radix Isatidis.

As a kind of prioritization scheme:

Described Chinese medicine composition is comprised of following component:

20 grams of Herba Pogostemoniss, 20 grams of Radix Saposhnikoviaes, 20 grams of Radix Paeoniae Rubra, 20 grams of Cortex Phellodendris, 20 grams of Bulbus Fritillariae Uninbracteataes, 20 grams of Rhizoma Coptidis, 20 grams of Herba Dendrobiis, 12 grams of the Rhizoma Pinelliaes, 12 grams of the Radixs Angelicae Dahuricae, 12 grams of Medulla Juncies, 12 grams of Rhizoma Coptidis, 12 grams of Fructus Forsythiaes, 12 grams, Folium Bambusae, 12 grams of Periostracum Cicadaes, 20 grams of Herba Menthaes, 12 grams of Radix Isatidis.

As a kind of prioritization scheme:

Described Chinese medicine composition is comprised of following component:

10 grams of Herba Pogostemoniss, 20 grams of Radix Saposhnikoviaes, 20 grams of Radix Paeoniae Rubra, 10 grams of Cortex Phellodendris, 15 grams of Bulbus Fritillariae Uninbracteataes, 15 grams of Rhizoma Coptidis, 20 grams of Herba Dendrobiis, 8 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Angelicae Dahuricae, 10 grams of Medulla Juncies, 12 grams of Rhizoma Coptidis, 12 grams of Fructus Forsythiaes, 8 grams, Folium Bambusae, 10 grams of Periostracum Cicadaes, 20 grams of Herba Menthaes, 12 grams of Radix Isatidis.

As a kind of prioritization scheme:

Described Chinese medicine composition is comprised of following component:

15 grams of Herba Pogostemoniss, 15 grams of Radix Saposhnikoviaes, 15 grams of Radix Paeoniae Rubra, 15 grams of Cortex Phellodendris, 15 grams of Bulbus Fritillariae Uninbracteataes, 15 grams of Rhizoma Coptidis, 15 grams of Herba Dendrobiis, 10 grams of the Rhizoma Pinelliaes, 10 grams of the Radixs Angelicae Dahuricae, 10 grams of Medulla Juncies, 10 grams of Rhizoma Coptidis, 10 grams of Fructus Forsythiaes, 10 grams, Folium Bambusae, 10 grams of Periostracum Cicadaes, 15 grams of Herba Menthaes, 10 grams of Radix Isatidis.

As a kind of prioritization scheme:

Described Chinese medicine composition is comprised of following component:

Chinese medicine in described Chinese medicine composition is got 100 grams after mixing by weight, add 800 milliliters, water, decocts to 500 milliliters, and elimination medicinal residues, obtain oral administration solution.

Wherein:

Herba Pogostemonis, has removing dampness by means of aromatics, stomach function regulating preventing or arresting vomiting, the effect of dispelling summer-heat from superficies of the body.The gastral cavity abdomen painful abdominal mass of main retention of dampness in middle-JIAO is vexed, inappetence, vomiting, has loose bowels, the headache of the cold and heat of diseases caused by exogenous pathogenic factor heat-damp in summer, hygropyrexia from the beginning of heating body tired, uncomfortable in chestly feel sick, nasal sinusitis, tinea manus and pedis.

Radix Saposhnikoviae, acrid in the mouth, sweet, slightly warm in nature.Return bladder, liver, spleen channel.There is expelling pathogenic wind from the body surface, removing dampness to relieve pain, the effect that relieving convulsion is jerked surely.Cure mainly: diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus.Radix Saposhnikoviae also can diaphoresis hidroschesis, antidiarrheal relieving constipation, hemostasis are stimulated the menstrual flow, antipyretic, calm, antiinflammatory, adjusting immunity.

Radix Paeoniae Rubra, bitter in the mouth, cold nature.Return Liver Channel.There is clots absorbing pain relieving, the effect of removing heat from blood detumescence.Control stomachache, hypochondriac pain, dysentery, spits blood, discharging fresh blood stool.The fever of the body that is used for the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases is hemorrhage, maculae caused by violent heat pathogen, conjunctival congestion and swelling pain, carbuncle sore tumefacting virus, the stagnant hypochondriac pain of the stasis of blood.

Cortex Phellodendri, hardship, cold.Return kidney channel; Bladder; Large intestine channel.Have heat clearing and damp drying, pathogenic fire purging is except steaming, the effect of detoxification sore treatment.Cure mainly: hygropyretic dysentery, have loose bowels, jaundice, hectic fever due to YIN-deficiency consumptive fever, night sweat, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema.Cortex Phellodendri is antibacterial, antitussive, hypotensive effect in addition.

Bulbus Fritillariae Uninbracteatae, bitter, sweet, be slightly cold.Return lung, heart channel.The merit that has relieving cough and resolving phlegm, heat clearing away eliminating stagnation.For cough due to lung-heat, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood.

Rhizoma Coptidis, bitter in the mouth cold in nature, has the function of dampness heat clearing away, eliminating fire and detoxication.

Herba Dendrobii, property slightly sweet flavor, micro-salty, cold, return stomach, kidney, lung meridian.There is reinforcing stomach reg fluid, the effect of nourishing YIN and clearing away heat.For cloudy impairment of body fluid, lose, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.

The Rhizoma Pinelliae, has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache, vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus.The Rhizoma Pinelliae also has that town is told, the effect of emetic, antiulcer, arrhythmia, anticoagulant, tranquilizing soporific.

The Radix Angelicae Dahuricae, pungent, temperature.Enter lung, spleen, stomach warp.The function that has the dehumidifying of getting rid of illness, evacuation of pus granulation promoting, promoting blood circulation and stopping pain.Cure mainly anemofrigid cold, headache, rhinitis, toothache, pain furuncle and phyma poison, supraorbital bone pain, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, ulcer sores, skin pruritus due to dryness, scabies.The Radix Angelicae Dahuricae is Anhydroalkannin, antipyretic-antalgic, spasmolytic, antibacterial, radioprotective also.

Medulla Junci, has clearing heart fire, and the effect of inducing diuresis for treating stranguria syndrome can be controlled gonorrhea, edema, dysphoria and insomnia, sore throat, wound, dysuria, jaundice due to damp-heat, the nocturnal fretfulness in infants.

Rhizoma Coptidis, hardship, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.There is heat clearing and damp drying, the effect of eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle, external treatment eczema, eczema, auditory meatus is suppurated.Rhizoma Coptidis also can be antibacterial, antiviral, and antiinflammatory, diarrhea, antipyretic, antiulcer.

Fructus Forsythiae, has heat-clearing and toxic substances removing, disappears and tie the effect of evacuation of pus.Its contained rutin can strengthen the density of blood capillary, therefore hemorrhage, the subcutaneous hemorrhage of capillary rupture is had to anastalsis.Fructus Forsythiae also has that antiinflammatory, antipyretic, antibacterial, antiviral, town are told, the effect of analgesia, diuresis, heart tonifying.

Folium Bambusae, has clearing heat and relieving fidgetness, the effect of the diuresis of promoting the production of body fluid.Control calentura excessive thirst, pediatric epilepsy scared, cough with dyspnea is told nosebleed, flushed complexion, oliguria with reddish urine, erosion of the oral mucosa tongue boil.Folium Bambosae extract effective ingredient comprises flavone, phenolic ketone, anthraquinone, lactone, polysaccharide, aminoacid, trace element etc., has the effect of good free radical resisting, antioxidation, resisting fatigue, blood fat reducing, prevention cardiovascular and cerebrovascular disease, the liver protecting, expansion blood capillary, dredging microcirculation, activation brain, promotion memory, improvement sleep.

Periostracum Cicadae is sweet salty, cool.Enter lung, Liver Channel.Dispelling wind-heat, expelling wind and relieving convulsion, rash sore-throat relieving, removing nebula to improve visual acuity.For anemopyretic cold, fever with chills, cough, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, tetanus.

Herba Menthae, cool in nature, acrid in the mouth.Return liver, lung meridian.The effect with dispelling wind and heat pathogens, the clear sharp head, the resolving depression of regulating the flow of vital energy.For headache, conjunctival congestion, sore throat, aphtha, the breast side of body rises vexed.The water decoction of Herba Menthae can anti-inflammatory analgetic, appetite stimulator, help digest, enhance metabolism.

Radix Isatidis, nature and flavor are bitter, cold.Return liver, stomach warp.Have bactericidal antiphlogistic, heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving, effect.Cure mainly the disease due to warm poison, as calentura is sent out speckle, influenza, upper respiratory tract infection, epidemic encephalitis, parotitis, acute enteritis, bacillary dysentery, facial erysipelas.

Hand-foot-mouth disease belongs to Chinese medicine " epidemic febrile disease " category.Cause hygropyrexia pathogen per os intranasal accumulates lung spleen.Heresy just disaccords, outer loose extremity, and upper smoked oropharynx, reaches skin outward, forms hemisphere herpes.If evil malicious high Sheng, the cardiopulmonary that cave in, priming liver-wind can occur that the collapse syndrome caused by dyspnea wind symptom danger such as heating, coma, breathing dyspnea with rapid and short breath, tic of the limbs, limbs flaccidity be soft wait, threat to life.Control suitable heat-clearing and toxic substances removing, expelling pathogenic factors from the exterior dampness removing.

Chinese medicine composition of the present invention is by drawing after clinical prescription compatibility for several times, the effect with heat-clearing and toxic substances removing, reinforcing the heart lung heat clearing, heat clearing away purgation of spleen excess, after taking, medicine arrives focus, prove effective rapidly, outer expelling pathogenic factors from muscles table, interior clear turbid damp, make the evil expelling heat from the exterior of the exterior and the interior, just middle pathogenesis, thus reach the object that regulates function, Yin Yang balancing, strengthening vital QI to eliminate pathogenic factors, can thoroughly remove the symptoms such as heating, headache, stomatalgia, pharyngalgia, erythra, ulcer and anorexia, by Comprehensive Treatment, improved immunity of organisms, cure hand-foot-mouth disease.

In addition, Chinese medicine preparation of the present invention does not develop immunity to drugs, and has no side effect, and be seven days each course for the treatment of, generally take two to three the course for the treatment of hand-foot-mouth disease just can be cured, clinical total effective rate is more than 97%.

Manufacture method of the present invention:

After above-mentioned Chinese medicine is mixed by weight, add 800 milliliters, water, decoct to 500 milliliters, filtering medicinal residues, obtain oral liquid.As need, make after tablet, powder, pill or capsule can mix above-mentioned Chinese medicine by weight and be ground into end, make tablet, powder, pill or capsule.

Instructions of taking: every day potion, every day three times, bfore meals, within seven days, be a course for the treatment of.

We have selected 86 routine hand-foot-mouth disease infants to carry out clinical verification to the treatment curative effect of Chinese medicine composition of the present invention.

86 routine hand-foot-mouth disease infants are divided into two groups at random, every group of each 43 examples.In treatment group, male 20 examples, female's 23 examples; 6 months～5 years old age, average (2.12 ± 1.05) year, average disease time (2.34 ± 1.05) day; In the routine infant for the treatment of group 43, there are heating person's 29 examples (67.42%), there are typical brothers symptom 43 examples (100%), there are oral ulcer person's 39 examples (90.7%), buttocks has papulovesicle person's 27 examples (62.8%), trunk has papulovesicle person's 22 examples (51.16%), knee has papulovesicle person to be respectively 7 examples (16.28%), cervical region and volume submental lymph nodes enlargement person 12 examples (27.91%).In matched group, male 19 examples, female's 24 examples; 1 years old～5 years old age, average (2.16 ± 1.04) year, average disease time (2.04 ± 1.01) day; In the routine infant of matched group 43, there are heating person's 28 examples (65.12%), there are typical brothers symptom 43 examples (100%), there are oral ulcer person's 38 examples (88.37%), buttocks has papulovesicle person's 27 examples (62.8%), trunk has papulovesicle person's 21 examples (48.84%), knee has papulovesicle person to be respectively 8 examples (18.61%), cervical region and volume submental lymph nodes enlargement person 11 examples (25.58%).Two groups of infants, at aspect difference not statistically significants (P>0.05) such as age, sex, the state of an illness, have comparability, and all infants are all without severe complication.

Hand-foot-mouth disease diagnostic criteria is clinical has following characteristics: 1. epidemic season, infant contact history; 2. hands, foot, mouth, buttocks erythra, accompany or the heat that do not occur together; 3. erythra, take brothers' metacarpus as feature, and herpes basilar part is wound with blush, and some cases herpes occurs in buttocks portion; 4. herpes of mouth is general with brothers' herpes while or prior to brothers' herpes.

Therapeutic Method: under the prerequisite of routine administration, the oral medicine of the present invention for the treatment of group is decocted rear oral administration solution, every day, potion, every day three times, each 160 milliliters, bfore meals.Matched group gives ribavirin granule, and 10～15mg/ (kg.d) minute 3 times oral.All take 7 days as a course for the treatment of for two groups.During treatment, all give antipyretic, isolation, intensive care, light diet, the anti symptom treatment such as drink more water.

Efficacy determination is with judgement curative effects such as heating, erythra, oral ulcer improvement disappear.Effective: treat 4～5 days, heat is moved back, oral ulcer and herpes all disappear or substantially disappear.Effective: treat 6～7 days above-mentioned symptoms, signs and substantially disappear, pars oralis pharyngis ulcer heals substantially.Invalid: to treat 7 days above above-mentioned symptoms, sign without obvious change.

Check: statistical method enumeration data relatively adopts χ ²check.Measurement data relatively with represent, adopt t check.The difference of P<0.05 has statistical significance.

1. curative effect comparisons as a result: treatment group total effective rate 97.67%, apparently higher than 86.05%, two group of matched group total effective rate, compare P<0.01, difference has statistical significance, (in Table 1).

Table 1 treatment group and the comparison of matched group curative effect

Group	Number of cases	Effective n (%)	Effective n (%)	Invalid n (%)	Total effective rate n (%)
						Treatment group	43	40(93.02)	2(4.65)	1(2.33)	42(97.67)
Matched group	43	23(53.49)	14(32.56)	6(13.95)	37(86.05)

Untoward reaction: treatment group is without generations such as erythra and leukopenia, and erythra 1 example (2.33%) appears in matched group, leukopenia 3 examples (6.98%).

2. symptom, sign extinction time and healing time comparison: treatment group is all better than matched group (P<0.05) at aspects such as symptom, sign extinction time and healing times.In Table 2.

Table 2 liang group symptom, sign extinction time and healing time comparison d

Group	Number of cases	Heating	Oral ulcer	Brothers' erythra	Curative day
						Treatment group	43	2.36±1.2	4.59±2.51	3.56±2.23	4.09±2.27
Matched group	43	3.47±3.55	6.59±3.67	6.39±2.68	7.98±2.29

Note: treatment group and matched group comparison, P>0.05, has statistical significance.

By table 1, table 2 relatively, treatment group and matched group comparative effectiveness are remarkable, and obviously shorten the course for the treatment of; Use traditional Chinese medicine composition for treating hand-foot-mouth disease of the present invention evident in efficacy, advantage is outstanding, and its fever time, oral ulcer and deflorescence time obviously shorten, and easy, easy row, has no side effect.

The specific embodiment

Embodiment 1: a kind of Chinese medicine composition for the treatment of hand-foot-mouth disease, choose 10 grams of Herba Pogostemoniss, 10 grams of Radix Saposhnikoviaes, 10 grams of Radix Paeoniae Rubra, 10 grams of Cortex Phellodendris, 10 grams of Bulbus Fritillariae Uninbracteataes, 10 grams of Rhizoma Coptidis, 10 grams of Herba Dendrobiis, 8 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Angelicae Dahuricae, 8 grams of Medulla Juncies, 8 grams of Rhizoma Coptidis, 8 grams of Fructus Forsythiaes, 8 grams, Folium Bambusae, 8 grams of Periostracum Cicadaes, 10 grams of Herba Menthaes, 8 grams of Radix Isatidis, after mixing, get 100 grams and add 800 milliliters, water, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, within seven days, be a course for the treatment of.

Embodiment 2: a kind of Chinese medicine composition for the treatment of hand-foot-mouth disease, choose 20 grams of Herba Pogostemoniss, 20 grams of Radix Saposhnikoviaes, 20 grams of Radix Paeoniae Rubra, 20 grams of Cortex Phellodendris, 20 grams of Bulbus Fritillariae Uninbracteataes, 20 grams of Rhizoma Coptidis, 20 grams of Herba Dendrobiis, 12 grams of the Rhizoma Pinelliaes, 12 grams of the Radixs Angelicae Dahuricae, 12 grams of Medulla Juncies, 12 grams of Rhizoma Coptidis, 12 grams of Fructus Forsythiaes, 12 grams, Folium Bambusae, 12 grams of Periostracum Cicadaes, 20 grams of Herba Menthaes, 12 grams of Radix Isatidis, after mixing, get 100 grams and add 800 milliliters, water, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, within seven days, be a course for the treatment of.

Embodiment 3: a kind of Chinese medicine composition for the treatment of hand-foot-mouth disease, choose 10 grams of Herba Pogostemoniss, 20 grams of Radix Saposhnikoviaes, 20 grams of Radix Paeoniae Rubra, 10 grams of Cortex Phellodendris, 15 grams of Bulbus Fritillariae Uninbracteataes, 15 grams of Rhizoma Coptidis, 20 grams of Herba Dendrobiis, 8 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Angelicae Dahuricae, 10 grams of Medulla Juncies, 12 grams of Rhizoma Coptidis, 12 grams of Fructus Forsythiaes, 8 grams, Folium Bambusae, 10 grams of Periostracum Cicadaes, 20 grams of Herba Menthaes, 12 grams of Radix Isatidis, after mixing, get 100 grams and add 800 milliliters, water, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, within seven days, be a course for the treatment of.

Embodiment 4: a kind of Chinese medicine composition for the treatment of hand-foot-mouth disease, choose 15 grams of Herba Pogostemoniss, 15 grams of Radix Saposhnikoviaes, 15 grams of Radix Paeoniae Rubra, 15 grams of Cortex Phellodendris, 15 grams of Bulbus Fritillariae Uninbracteataes, 15 grams of Rhizoma Coptidis, 15 grams of Herba Dendrobiis, 10 grams of the Rhizoma Pinelliaes, 10 grams of the Radixs Angelicae Dahuricae, 10 grams of Medulla Juncies, 10 grams of Rhizoma Coptidis, 10 grams of Fructus Forsythiaes, 10 grams, Folium Bambusae, 10 grams of Periostracum Cicadaes, 15 grams of Herba Menthaes, 10 grams of Radix Isatidis, after mixing, get 100 grams and add 800 milliliters, water, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, within seven days, be a course for the treatment of.

Some patients were healing case is as follows:

Zhao, female, 5 years old, infant was without obvious inducement generation stomatocace before 4 days, and pain is obvious, impact feed.Then there is red macule, slightly gargalesthesia in palm vola.Palate, lower lip is all dispersed in grain of rice size ulcer surface as seen, is covered with yellow pseudomembrane, and periphery is ruddy.The enlargement that both sides submandibular lymph nodes touches.Palm vola is dispersed in red grouper pimple as seen, and aobvious symmetric row distributes.Through hospital diagnosis, be hand-foot-mouth disease, coordinate hospitalize poor effect, take Chinese medicine composition of the present invention after three days disease from removing, recovered health, follow up a case by regular visits to and have no recurrence.

In certain, female, 1 years old 2 months, infant started occur to send out heating before 3 days, high fever 38.5 degree, bring down a fever after taking Merrill Lynch.Second day oral cavity, hands, foot, buttocks start to occur herpes, are hand-foot-mouth disease after diagnosing, coordinate after hospitalize, and infant not heating in two days, diet is slightly poor, and daytime is in high spirits, the uneasiness but cry and scream night.Infant buttocks erythra increases, and through taking Chinese medicine composition of the present invention after five days, oral cavity, hands, foot, buttocks herpes disappear, and health recovery from illness, follows up a case by regular visits to and have no recurrence.

Side certain, man, 5 years old.There is heating in infant, headache is because of oral ulcer before 3 days, both hands portion pimple pharyngeal hyperemia, and the tip of the tongue, the larger ulcer surface in visible two places, Sublingual, the both hands heart and the back of the hand little red pimple that mays be seen indistinctly, individually with vesicle, goes to see a doctor, and is diagnosed as hand, mouth and foot diseases.Treat poor effect.Take Chinese medicine composition of the present invention two days later oral ulcer, both hands red pimple symptom alleviate, take again two days, disease disappears, and follows up a case by regular visits to and has no recurrence.

Hao, man 3 years old, infant fever, day sialorrhea, brothers' skin ulcer rash 2 days.The oral cavity the tip of the tongue has a ulcer, brothers affected part can occur punctation, and speckle progressively develops into skin ulcer rash.In skin ulcer rash, be slightly turbid liquid, be diagnosed as hand-foot-mouth disease.Take Chinese medicine composition of the present invention, ulcer, speckle disappear two days later, and symptom is from removing.Follow up a case by regular visits to and have no recurrence.

Claims (5)

1. a Chinese medicine composition for the treatment of hand-foot-mouth disease, is characterized in that: this Chinese medicine composition is comprised of following component:

Herba Pogostemonis 10-20 gram, Radix Saposhnikoviae 10-20 gram, Radix Paeoniae Rubra 10-20 gram, Cortex Phellodendri 10-20 gram, Bulbus Fritillariae Uninbracteatae 10-20 gram, Rhizoma Coptidis 10-20 gram, Herba Dendrobii 10-20 gram, Rhizoma Pinelliae 8-12 gram, Radix Angelicae Dahuricae 8-12 gram, Medulla Junci 8-12 gram, Rhizoma Coptidis 8-12 gram, Fructus Forsythiae 8-12 gram, Folium Bambusae 8-12 gram, Periostracum Cicadae 8-12 gram, Herba Menthae 10-20 gram, Radix Isatidis 8-12 gram.

2. the Chinese medicine composition for the treatment of hand-foot-mouth disease according to claim 1, is characterized in that: described Chinese medicine composition is comprised of following component:

10 grams of Herba Pogostemoniss, 10 grams of Radix Saposhnikoviaes, 10 grams of Radix Paeoniae Rubra, 10 grams of Cortex Phellodendris, 10 grams of Bulbus Fritillariae Uninbracteataes, 10 grams of Rhizoma Coptidis, 10 grams of Herba Dendrobiis, 8 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Angelicae Dahuricae, 8 grams of Medulla Juncies, 8 grams of Rhizoma Coptidis, 8 grams of Fructus Forsythiaes, 8 grams, Folium Bambusae, 8 grams of Periostracum Cicadaes, 10 grams of Herba Menthaes, 8 grams of Radix Isatidis.

3. the Chinese medicine composition for the treatment of hand-foot-mouth disease according to claim 1, is characterized in that: described Chinese medicine composition is comprised of following component:

20 grams of Herba Pogostemoniss, 20 grams of Radix Saposhnikoviaes, 20 grams of Radix Paeoniae Rubra, 20 grams of Cortex Phellodendris, 20 grams of Bulbus Fritillariae Uninbracteataes, 20 grams of Rhizoma Coptidis, 20 grams of Herba Dendrobiis, 12 grams of the Rhizoma Pinelliaes, 12 grams of the Radixs Angelicae Dahuricae, 12 grams of Medulla Juncies, 12 grams of Rhizoma Coptidis, 12 grams of Fructus Forsythiaes, 12 grams, Folium Bambusae, 12 grams of Periostracum Cicadaes, 20 grams of Herba Menthaes, 12 grams of Radix Isatidis.

4. the Chinese medicine composition for the treatment of hand-foot-mouth disease according to claim 1, is characterized in that: described Chinese medicine composition is comprised of following component:

10 grams of Herba Pogostemoniss, 20 grams of Radix Saposhnikoviaes, 20 grams of Radix Paeoniae Rubra, 10 grams of Cortex Phellodendris, 15 grams of Bulbus Fritillariae Uninbracteataes, 15 grams of Rhizoma Coptidis, 20 grams of Herba Dendrobiis, 8 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Angelicae Dahuricae, 10 grams of Medulla Juncies, 12 grams of Rhizoma Coptidis, 12 grams of Fructus Forsythiaes, 8 grams, Folium Bambusae, 10 grams of Periostracum Cicadaes, 20 grams of Herba Menthaes, 12 grams of Radix Isatidis.

5. the Chinese medicine composition for the treatment of hand-foot-mouth disease according to claim 1, is characterized in that: described Chinese medicine composition is comprised of following component:

15 grams of Herba Pogostemoniss, 15 grams of Radix Saposhnikoviaes, 15 grams of Radix Paeoniae Rubra, 15 grams of Cortex Phellodendris, 15 grams of Bulbus Fritillariae Uninbracteataes, 15 grams of Rhizoma Coptidis, 15 grams of Herba Dendrobiis, 10 grams of the Rhizoma Pinelliaes, 10 grams of the Radixs Angelicae Dahuricae, 10 grams of Medulla Juncies, 10 grams of Rhizoma Coptidis, 10 grams of Fructus Forsythiaes, 10 grams, Folium Bambusae, 10 grams of Periostracum Cicadaes, 15 grams of Herba Menthaes, 10 grams of Radix Isatidis.