CN104189539A - Traditional Chinese medicine for treating allergic rhinitis - Google Patents

Abstract

The invention discloses a traditional Chinese medicine for treating allergic rhinitis. The traditional Chinese medicine is prepared from the following active pharmaceutical ingredients by weight: 5-15g of manyprickle acathopanax root, 10-20g of radix astragali, 10-20g of white hyacinth bean, 10-20g of Indian bread, 2-8g of biond magnolia flower, 10-20g of euphorbia helioscopia, 5-15g of perilla, 5-15g of Siberian cocklebur fruit, 2-8g of small centipeda herb, 2-6g of kudzuvine root, 1-4g of manchurian wildginger, 2-6g of great burdock achene, 5-15g of Chinese gall, 5-15g of rhizoma polygonati, 10-15g of folium phyllostachys and 2-6g of licorice roots northwest origin. The traditional Chinese medicine has the functions of invigorating the spleen and replenishing qi, warming phlegm and retained fluid and dispelling wind to dredge orifices, is wide in medicine sources, is harmless to human bodies and has obvious allergic rhinitis treatment effects. Through statistics of 110 clinical therapies, the effective rate and good rate of the traditional Chinese medicine are respectively 84.5% and 91.7%.

Description

The Chinese medicine for the treatment of of allergic rhinitis

 

Technical field

The present invention relates to contain the medicinal preparation that derives from plant material, particularly a kind of Chinese medicine for the treatment of of allergic rhinitis.

 

Background technology

Allergic rhinitis is that allergic rhinitis (allergic rhinitis) claims again allergic rhinitis, is that atopic individuals contacts the nasal mucosa chronic inflammatory reaction disease that the medium (being mainly histamine) being mediated by IgE after sensitinogen discharges and has panimmunity competent cell and cytokine etc. to participate in.The classical symptom of allergic rhinitis is mainly the outbreak of paroxysmal sneeze seriality, and secondly a large amount of water sample thin nasal discharge are nasal obstruction and rhinocnesmus.Some patients were has hyposmia, but is temporary.Chronic simple rhinitis is the dysfunction of nervous regulation disorder based on nasal cavity blood vessel, parasympathetic nervous excitement is preponderated, and sympathetic nerve is relative inhibitory state, and hyperamization enlargement of pipe, glandular secretion increases, and forms a kind of chronic inflammatory disease taking mucosa swelling, secretions increase as feature.Allergic rhinitis and sinusitis have many very alike symptoms, and the cause of sinusitis can be flu, can be also irritated or viral.These causes of disease all can cause nasal sinuses inflammation.

In the view of a lot of people, a little painful, still the same with Healthy People later when allergic rhinitis is only showing effect, control that it doesn't matter.In fact, if allergic rhinitis is treated not in time, also may bring out multiple complication, modal is bronchial asthma, also concurrent sinusitis, the nasal polyp that have, otitis media, anaphylaxis pharyngolaryngitis, anosmia etc., so, very important to allergic rhinitis, early control anti-morning.In normal population, asthma prevalence is about 2%-5%, and in Allergic Rhinitis, asthma prevalence is about 20%-40%, and even 60% allergic rhinitis patient may develop into asthma.Because allergic rhinitis can develop into asthma, therefore to fully recognize that active treatment rhinitis carrys out the importance of prevention of asthma.

Allergic rhinitis can betide any age, and comparatively common with seasonality outbreak.The symptom of allergic rhinitis is similar to flu, therefore, has many patients often allergic rhinitis to be treated as to flu at the initial stage of a disease, takes voluntarily anti-cold medicine or go to a doctor to obtain correct diagnosis and treatment in time in other section office.Allergic rhinitis is a kind of obstinate disease, not only treats difficulty large, and very easily recurrence, is difficult to thoroughly cure.Western medicine allergic rhinitis, cures the symptoms, not the disease, and the words of life-time service easily have side effects.Conventional treatment sinusitis, the medicine of chronic rhinitis is not good to the therapeutic effect of allergic rhinitis.

According to theory of Chinese medical science, nose is key on lung, and lung and nose can be known good and foul smells.If insufficiency of lung-QI, ailment said due to cold or exposure is violated lung, struggle between vital QI and pathogen, and eliminating evil going out, sneeze is done frequently.Insufficiency of lung-QI, dereliction of duty falls in a surname, and body fluid loses in cloth, and Tianjin water is excessive, thin nasal discharge gravity flow, Tianjin water retention is poly-, nasal obstruction.The reason of insufficiency of lung-QI, the one, insufficiency of the spleen mistake fortune, essence of water and grain can not be gone up flourish in lung, lung qi day void; The 2nd, prolonged illness impairment caused by overstrain, consume lung qi and cause insufficiency of lung-QI.If disease does not heal for a long time, illness of child viscera affecting mother one, also forms asthenia of pulmonosplenic qi.Two is dirty all empty thus, and the power of defending outer defence is more weak.The invention provides a kind of invigorating the spleen and benefiting QI, the temperature drink that reduces phlegm, the Chinese medicine of a kind for the treatment of of allergic rhinitis of expelling pathogenic wind and restoring the functions of orifices in face.

 

Summary of the invention

Technical problem to be solved by this invention is, a kind of invigorating the spleen and benefiting QI is provided, the temperature drink that reduces phlegm, Chinese medicine of a kind for the treatment of of allergic rhinitis of expelling pathogenic wind and restoring the functions of orifices in face and preparation method thereof.

For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine for the treatment of of allergic rhinitis, wherein, each crude drug is as follows than configuration according to weight fraction: Radix Et Caulis Acanthopanacis Senticosi 5-15g, Radix Astragali 10-20g, Semen Lablab Album 10-20g, Poria 10-20g, Flos Magnoliae 2-8g, Herba Euphorbiae Helioscopiae 10-20g, Folium Perillae 5-15g, Fructus Xanthii 5-15g, Herba Centipedae 2-8g, Radix Puerariae 2-6g, Herba Asari 1-4g, Fructus Arctii 2-6g, Galla Chinensis 5-15g, Rhizoma Polygonati 5-15g, Folium Bambusae 10-15g, Radix Glycyrrhizae 2-6g.

Or each crude drug is as follows than configuration according to weight fraction: Radix Et Caulis Acanthopanacis Senticosi 8-15g, Radix Astragali 13-20g, Semen Lablab Album 13-20g, Poria 13-20g, Flos Magnoliae 5-8g, Herba Euphorbiae Helioscopiae 13-20g, Folium Perillae 8-15g, Fructus Xanthii 8-15g, Herba Centipedae 5-8g, Radix Puerariae 3-6g, Herba Asari 2-4g, Fructus Arctii 3-6g, Galla Chinensis 8-15g, Rhizoma Polygonati 8-15g, Folium Bambusae 12-15g, Radix Glycyrrhizae 4-6g.

Or each crude drug is as follows than configuration according to weight fraction: Radix Et Caulis Acanthopanacis Senticosi 5-12g, Radix Astragali 10-15g, Semen Lablab Album 10-15g, Poria 10-15g, Flos Magnoliae 2-6g, Herba Euphorbiae Helioscopiae 10-15g, Folium Perillae 5-12g, Fructus Xanthii 5-12g, Herba Centipedae 2-6g, Radix Puerariae 2-4g, Herba Asari 1-3g, Fructus Arctii 2-4g, Galla Chinensis 5-10g, Rhizoma Polygonati 5-10g, Folium Bambusae 10-14g, Radix Glycyrrhizae 2-5g.

Or each crude drug is as follows than configuration according to weight fraction: Radix Et Caulis Acanthopanacis Senticosi 8-12g, Radix Astragali 13-15g, Semen Lablab Album 13-15g, Poria 13-15g, Flos Magnoliae 5-6g, Herba Euphorbiae Helioscopiae 13-15g, Folium Perillae 8-12g, Fructus Xanthii 8-12g, Herba Centipedae 5-6g, Radix Puerariae 3-4g, Herba Asari 2-3g, Fructus Arctii 3-4g, Galla Chinensis 8-10g, Rhizoma Polygonati 8-10g, Folium Bambusae 12-14g, Radix Glycyrrhizae 4-5g.

 

Object to better implement the present invention, the present invention also provides a kind of preparation method of Chinese medicine for the treatment of of allergic rhinitis, and wherein, in the time that Chinese medicine is honey refining pill, its preparation method is as follows:

Each crude drug is soaked 30 minutes to 1 hour, and heated and boiled 30 minutes, filters, and filtrate is for subsequent use; Filtering residue adds water, and heating, boils 30 minutes for the second time, refilters, and filtrate is for subsequent use; Filtering residue adds water again, and heated and boiled 40 minutes is for the third time filtered; Three filtrates are combined, and heating is concentrated into pasty state, puts into baking oven, is controlled at 80 DEG C, cooling after drying, and mixes and is twisted into slice, pill wax seal packaging with Mel;

Or when the dosage form of Chinese medicine is capsule, its preparation method is as follows:

Each crude drug is added to the ethanol of 10 times of amounts of gross weight, heating and refluxing extraction 3 times, each 2 hours, 3 extracting solution are merged, decompression recycling ethanol, and to be concentrated into liquor strength be 0.5g crude drug/mL, after sucking filtration, when the relative density of filtrate is 20 DEG C 1.08; The adsorption resin column that described filtrate flow is 10L through volume, uses deionized water or the distilled water eluting of 10 times of resin column volumes afterwards, then uses 95% ethanol elution of 5 times of resin column volumes, collect ethanol elution, remove alcohol solvent, obtain component medicated powder, incapsulate and be made as capsule.

 

Expelling wind and cold of the present invention, Xin Wen is sensible, regulates vim and vigour, the stagnant blood stasis dispelling of row, warming the lung and benefiting QI, expelling pathogenic wind and restoring the functions of orifices in face, and medicine source is extensive, and harmless, treatment of allergic rhinitis effect is remarkable.Through 110 routine clinical statisticses, effective percentage reaches 84.5%, is well 91.7%.

 

Detailed description of the invention:

Side of the present invention separates: the present invention is with invigorating the spleen to benefit the lung, and loose wind profit key is main.Radix Et Caulis Acanthopanacis Senticosi, the Radix Astragali, Semen Lablab Album, Poria, Herba Euphorbiae Helioscopiae invigorating the spleen and benefiting QI in side, be monarch drug, and wherein Semen Lablab Album, Poria, Herba Euphorbiae Helioscopiae are got the justice of building up the spleen to supplement the lung, exactly by strengthening the spleen and stomach (soil) with the lung that gains (gold) gas.Folium Perillae, Flos Magnoliae, Fructus Xanthii, Folium Perillae, Herba Centipedae, Herba Asari, Fructus Arctii expelling pathogenic wind and restoring the functions of orifices in face are ministerial drug.Folium Bambusae assistant Radix Et Caulis Acanthopanacis Senticosi, Semen Lablab Album, can strengthen the effect of invigorating the spleen and replenishing QI.Rhizoma Polygonati, Galla Chinensis 5 use, the meaning of the solid lung of convergence, is all adjuvant drug.Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, and can separate the poison of Herba Asari, for making medicine.

The preparation method of the Chinese medicine for the treatment of of allergic rhinitis of the present invention, wherein, in the time that Chinese medicine is honey refining pill, its preparation method is as follows:

Each crude drug is soaked 30 minutes to 1 hour, and heated and boiled 30 minutes, filters, and filtrate is for subsequent use; Filtering residue adds water, and heating, boils 30 minutes for the second time, refilters, and filtrate is for subsequent use; Filtering residue adds water again, and heated and boiled 40 minutes is for the third time filtered; Three filtrates are combined, and heating is concentrated into pasty state, puts into baking oven, is controlled at 80 DEG C, cooling after drying, and mixes and is twisted into slice, pill wax seal packaging with Mel;

Or when the dosage form of Chinese medicine is capsule, its preparation method is as follows:

Each crude drug is added to the ethanol of 10 times of amounts of gross weight, heating and refluxing extraction 3 times, each 2 hours, 3 extracting solution are merged, decompression recycling ethanol, and to be concentrated into liquor strength be 0.5g crude drug/mL, after sucking filtration, when the relative density of filtrate is 20 DEG C 1.08; The adsorption resin column that described filtrate flow is 10L through volume, uses deionized water or the distilled water eluting of 10 times of resin column volumes afterwards, then uses 95% ethanol elution of 5 times of resin column volumes, collect ethanol elution, remove alcohol solvent, obtain component medicated powder, incapsulate and be made as capsule.

 

Concrete example is as follows

Embodiment 1

Liu, 25 years old, female, quick property rhinitis, shows as repeated cold, and 8-15 days left flu once, show effect by flu one, paroxysmal sneeze, a large amount of water sample thin nasal discharge, nasal obstruction, rhinocnesmus.Hyposmia.Take following medicament: Radix Et Caulis Acanthopanacis Senticosi 15g, Radix Astragali 15g, Semen Lablab Album 15g, Poria 15g, Flos Magnoliae 6g, Herba Euphorbiae Helioscopiae 15g, Folium Perillae 10g, Fructus Xanthii 10g, Herba Centipedae 6g, Radix Puerariae 6g, Herba Asari 3g, Fructus Arctii 6g, Galla Chinensis 10g, Rhizoma Polygonati 10g, Folium Bambusae 10g, Radix Glycyrrhizae 6g.Be decocted in water for oral dose, every day is each potion sooner or later.Above-mentioned medicament is taken after 20 doses, and sneeze, thin nasal discharge, nasal obstruction, rhinocnesmus symptom obviously alleviate, and continues to take 15 doses, transference cure, and smooth breathing, continues to take 10 doses of drug withdrawals, cures.After half a year, visit, not recurrence.

 

Embodiment 2

Mrs Wang, 17 years old, constantly, continuously made a call to seven eight even more than ten sneezes once the sneeze of getting up every morning, then flows out clear nasal mucus from nostril, almost wipes away one's snivel with a large bag toilet paper every morning, and sneeze often tear also brings out.Take following medicament: Radix Et Caulis Acanthopanacis Senticosi 10g, Radix Astragali 10g, Semen Lablab Album 10g, Poria 10g, Flos Magnoliae 2g, Herba Euphorbiae Helioscopiae 10g, Folium Perillae 5g, Fructus Xanthii 5g, Herba Centipedae 2g, Radix Puerariae 2g, Herba Asari 1g, Fructus Arctii 2g, Galla Chinensis 5g, Rhizoma Polygonati 5g, Folium Bambusae 10g, Radix Glycyrrhizae 2g.Be decocted in water for oral dose, every day is each potion sooner or later.Above-mentioned medicament is taken after 10 doses, and 1 symptom obviously alleviates, and continues to take 5 doses of drug withdrawals, cures.After three months, visit, not recurrence.

 

Embodiment 3

Zhang, man.36 years old, symptom: nasal obstruction, rhinorrhea, sneeze have 5 years.Nasal obstruction, rhinorrhea repeatedly.Must madly sneeze every morning battle array do, after voluntarily medication fail to respond to any medical treatment fruit, repeatedly outbreak.After 2 years, be still nasal mucus as clear water, seriously nasal obstruction, with headache, and now starts to have had slight asthma to occur, often in flu state.Nasendoscopy: nasal cavity nasal mucosa congestion and edema, hypertrophic inferior turbinate, visible watery secretion.Take following medicament: Radix Et Caulis Acanthopanacis Senticosi 20g, Radix Astragali 20g, Semen Lablab Album 20g, Poria 20g, Flos Magnoliae 8g, Herba Euphorbiae Helioscopiae 20g, Folium Perillae 15g, Fructus Xanthii 15g, Herba Centipedae 8g, Radix Puerariae 6g, Herba Asari 4g, Fructus Arctii 6g, Galla Chinensis 15g, Rhizoma Polygonati 15g, Folium Bambusae 15g, Radix Glycyrrhizae 6g.

Be decocted in water for oral dose, every day is each potion sooner or later.Above-mentioned medicament is taken after 16 doses, and nasal obstruction rhinorrhea, sneeze, symptom obviously alleviate, and continue to take 12 doses, nasal obstruction, rhinorrhea, sneeze transference cure, and smooth breathing, continues to take 12 doses of drug withdrawals, cures.After three months, visit, not recurrence.

 

Embodiment 4,

Grandson, man.32 years old, symptom: nasal obstruction, rhinorrhea, sneeze have 3 years.Nasal obstruction, rhinorrhea repeatedly.Must madly sneeze every morning battle array do, after voluntarily medication fail to respond to any medical treatment fruit, repeatedly outbreak.After 2 years, be still nasal mucus as clear water, seriously nasal obstruction, with headache, and now starts to have had slight asthma to occur, often in flu state.Nasendoscopy: nasal cavity nasal mucosa congestion and edema, hypertrophic inferior turbinate, visible watery secretion.Take following medicament: Radix Et Caulis Acanthopanacis Senticosi 12g, Radix Astragali 15g, Semen Lablab Album 15g, Poria 15g, Flos Magnoliae 6g, Herba Euphorbiae Helioscopiae 15g, Folium Perillae 10g, Fructus Xanthii 10g, Herba Centipedae 6g, Radix Puerariae 6g, Herba Asari 3g, Fructus Arctii 6g, Galla Chinensis 10g, Rhizoma Polygonati 10g, Folium Bambusae 10g, Radix Glycyrrhizae 6g,

Sign: asthenia of pulmonosplenic qi.

Fang Xie: side of the present invention separates: the present invention is with invigorating the spleen to benefit the lung, and loose wind profit key is main.Radix Et Caulis Acanthopanacis Senticosi, the Radix Astragali, Semen Lablab Album, Poria, Herba Euphorbiae Helioscopiae invigorating the spleen and benefiting QI in side, be monarch drug, and wherein Semen Lablab Album, Poria, Herba Euphorbiae Helioscopiae are got the justice of building up the spleen to supplement the lung, exactly by strengthening the spleen and stomach (soil) with the lung that gains (gold) gas.Folium Perillae, Flos Magnoliae, Fructus Xanthii, Folium Perillae, Herba Centipedae, Herba Asari, Fructus Arctii expelling pathogenic wind and restoring the functions of orifices in face are ministerial drug.Folium Bambusae assistant Radix Et Caulis Acanthopanacis Senticosi, Semen Lablab Album, can strengthen the effect of invigorating the spleen and replenishing QI.Rhizoma Polygonati, Galla Chinensis 5 use, the meaning of the solid lung of convergence, is all adjuvant drug.Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, and can separate the poison of Herba Asari, for making medicine.

Prescription foundation: according to theory of Chinese medical science, nose is key on lung, and lung and nose can be known good and foul smells.If insufficiency of lung-QI, ailment said due to cold or exposure is violated lung, struggle between vital QI and pathogen, and eliminating evil going out, sneeze is done frequently.Insufficiency of lung-QI, dereliction of duty falls in a surname, and body fluid loses in cloth, and Tianjin water is excessive, thin nasal discharge gravity flow, Tianjin water retention is poly-, nasal obstruction.The reason of insufficiency of lung-QI, the one, insufficiency of the spleen mistake fortune, essence of water and grain can not be gone up flourish in lung, lung qi day void; The 2nd, prolonged illness impairment caused by overstrain, consume lung qi and cause insufficiency of lung-QI.If disease does not heal for a long time, illness of child viscera affecting mother one, also forms asthenia of pulmonosplenic qi.Two is dirty all empty thus, and the power of defending outer defence is more weak.

Through clinical serious, this example is preferred example, and effective percentage is far above other examples.

 

Establishment of Rat Model

Select rat, etherization, rat left and right forelimb and hind leg inject respectively 0.1 and the antigen adjuvant suspension of 0.2ml (every milliliter containing ovalbumin 1mg, bordetella pertussis 10 ¹⁰individual and aluminium hydroxide 2mg) carry out sensitization, first sensitization was strengthened sensitization after 5 days, the ovalbumin of 0.5mg is dissolved in to 1ml normal saline and injects rat back.After first sensitization the 7th day starts to use once a day ovalbumin 1g/L collunarium, each 10 microlitres, and the continuous sneeze of rat, obtains rat allergic rhinitis model.

Use decoction of the present invention, 10 of rat models are gavaged to 5ml at every turn, within one day, gavage 2 times, as experimental group, 10 of rat models are used to ketotifens, as a control group one, do not use any medicine as blank group to 10 of rat models, be compared as follows

Group	Dosage	Sneeze number of times	Scratch nose number of times
				Experimental group	5ml	13.7±2.2	14.7±2.5
Matched group one	3mg/kg	27.9±2.8	13.8±3.2
				Blank group	--	35.2±4.2	22.8±3.5

By above-mentioned contrast, can find that this medicament has good therapeutic effect to allergic rhinitis.

Invigorating the spleen and benefiting QI of the present invention, the temperature drink that reduces phlegm, expelling pathogenic wind and restoring the functions of orifices in face, and medicine source is extensive, and harmless, treatment rhinitis effect is remarkable.Through 110 routine clinical statisticses, effective percentage reaches 84.5%, is well 91.7%.

Claims (5)

1. a Chinese medicine for treatment of allergic rhinitis, is characterized in that, each crude drug is as follows than configuration according to weight fraction: Radix Et Caulis Acanthopanacis Senticosi 5-15g, Radix Astragali 10-20g, Semen Lablab Album 10-20g, Poria 10-20g, Flos Magnoliae 2-8g, Herba Euphorbiae Helioscopiae 10-20g, Folium Perillae 5-15g, Fructus Xanthii 5-15g, Herba Centipedae 2-8g, Radix Puerariae 2-6g, Herba Asari 1-4g, Fructus Arctii 2-6g, Galla Chinensis 5-15g, Rhizoma Polygonati 5-15g, Folium Bambusae 10-15g, Radix Glycyrrhizae 2-6g.

2. the Chinese medicine for the treatment of of allergic rhinitis according to claim 1, is characterized in that, each crude drug is as follows than configuration according to weight fraction: Radix Et Caulis Acanthopanacis Senticosi 8-15g, Radix Astragali 13-20g, Semen Lablab Album 13-20g, Poria 13-20g, Flos Magnoliae 5-8g, Herba Euphorbiae Helioscopiae 13-20g, Folium Perillae 8-15g, Fructus Xanthii 8-15g, Herba Centipedae 5-8g, Radix Puerariae 3-6g, Herba Asari 2-4g, Fructus Arctii 3-6g, Galla Chinensis 8-15g, Rhizoma Polygonati 8-15g, Folium Bambusae 12-15g, Radix Glycyrrhizae 4-6g.

3. the Chinese medicine for the treatment of of allergic rhinitis according to claim 1, is characterized in that, each crude drug is as follows than configuration according to weight fraction: Radix Et Caulis Acanthopanacis Senticosi 5-12g, Radix Astragali 10-15g, Semen Lablab Album 10-15g, Poria 10-15g, Flos Magnoliae 2-6g, Herba Euphorbiae Helioscopiae 10-15g, Folium Perillae 5-12g, Fructus Xanthii 5-12g, Herba Centipedae 2-6g, Radix Puerariae 2-4g, Herba Asari 1-3g, Fructus Arctii 2-4g, Galla Chinensis 5-10g, Rhizoma Polygonati 5-10g, Folium Bambusae 10-14g, Radix Glycyrrhizae 2-5g.

4. the Chinese medicine for the treatment of of allergic rhinitis according to claim 1, is characterized in that, each crude drug is as follows than configuration according to weight fraction: Radix Et Caulis Acanthopanacis Senticosi 8-12g, Radix Astragali 13-15g, Semen Lablab Album 13-15g, Poria 13-15g, Flos Magnoliae 5-6g, Herba Euphorbiae Helioscopiae 13-15g, Folium Perillae 8-12g, Fructus Xanthii 8-12g, Herba Centipedae 5-6g, Radix Puerariae 3-4g, Herba Asari 2-3g, Fructus Arctii 3-4g, Galla Chinensis 8-10g, Rhizoma Polygonati 8-10g, Folium Bambusae 12-14g, Radix Glycyrrhizae 4-5g.

5. as described in as arbitrary in claim 1-4, a preparation method for the Chinese medicine for the treatment of of allergic rhinitis, is characterized in that, in the time that described Chinese medicine is honey refining pill, its preparation method is as follows:

Each crude drug is soaked 30 minutes to 1 hour, and heated and boiled 30 minutes, filters, and filtrate is for subsequent use; Filtering residue adds water, and heating, boils 30 minutes for the second time, refilters, and filtrate is for subsequent use; Filtering residue adds water again, and heated and boiled 40 minutes is for the third time filtered; Three filtrates are combined, and heating is concentrated into pasty state, puts into baking oven, is controlled at 80 DEG C, cooling after drying, and mixes and is twisted into slice, pill wax seal packaging with Mel;

Or when the dosage form of Chinese medicine is capsule, its preparation method is as follows:

Each crude drug is added to the ethanol of 10 times of amounts of gross weight, heating and refluxing extraction 3 times, each 2 hours, 3 extracting solution are merged, decompression recycling ethanol, and to be concentrated into liquor strength be 0.5g crude drug/ml, after sucking filtration, when the relative density of filtrate is 20 DEG C 1.08; The adsorption resin column that described filtrate flow is 10L through volume, uses deionized water or the distilled water eluting of 10 times of resin column volumes afterwards, then uses 95% ethanol elution of 5 times of resin column volumes, collect ethanol elution, remove alcohol solvent, obtain component medicated powder, incapsulate and be made as capsule.