CN104189254A - Active human placenta blood-enriching soft capsule and preparation process thereof - Google Patents
Active human placenta blood-enriching soft capsule and preparation process thereof Download PDFInfo
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- CN104189254A CN104189254A CN201410462158.0A CN201410462158A CN104189254A CN 104189254 A CN104189254 A CN 104189254A CN 201410462158 A CN201410462158 A CN 201410462158A CN 104189254 A CN104189254 A CN 104189254A
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Abstract
The invention relates to an active human placenta blood-enriching soft capsule and a preparation process thereof. The active human placenta blood-enriching soft capsule is prepared from the following raw materials in parts by weight: 4-6 parts of human placenta, 2-4 parts of angelica sinensis, 3-5 parts of semen cuscutae, 1-2 parts of lecithin and 3-5 parts of capsule carrier. The preparation method comprises the following steps: grinding the human placenta, the angelica sinensis, the semen cuscutae and Chinese wolfberry at the low temperature of 1-10 DEG C, and performing ultrasonic splitting for 30-50 minutes; performing vacuum freeze drying at minus 25 DEG C to minus 35 DEG C till the water content of medicine powder is less than 8%; crushing the medicine powder into 400-600 mesh micro powder at minus 15 DEG C to minus 25 DEG C, and adding lecithin and the soft capsule carrier, thereby obtaining the active human placenta blood-enriching soft capsule. As human placenta, the angelica sinensis and the semen cuscutae are adopted for compatibility, the active human placenta blood-enriching soft capsule has the effects of nourishing and strengthening, invigorating the kidney and strengthening Yang, strengthening the physical power and promoting health, and no patent technique or relevant report about active blood-enriching soft capsules which are prepared from human placenta, angelica sinensis and semen cuscutae as raw materials is available at present.
Description
Technical field
The present invention relates to a kind of blood enriching capsule, concrete a kind of Placenta Hominis activity enrich blood soft capsule and production technology thereof.
Background technology
Placenta Hominis, refers to that the mankind's Placenta Hominis, the traditional Chinese medical science think, Placenta Hominis nature and flavor are sweet, salty, warm, enter lung, the heart, kidney channel, have the kidney invigorating and essence nourishing, the merit of benefiting QI and nourishing blood.Modern medicine study is thought, Placenta Hominis is containing protein, sugar, calcium, vitamin, immune factor, estrogen, gravidity assisting ketone, steroid hormone, promoting sexual gland hormone, thyroliberin etc., can promote the growth of mammary gland, uterus, vagina, testis, thyroid is also had to facilitation, pulmonary tuberculosis, bronchial asthma, anemia etc. are also had to good effect, grind oral or coloclysis into powder and can prevent measles or mitigation symptoms.Portal cirrhotic ascites and schistosomicide end-age cirrhosis ascites are also had to certain curative effect.
Radix Angelicae Sinensis, sweet in the mouth and weighing, therefore specially can enrich blood, its gas is light and pungent, thus again can promoting the circulation of blood, invigorating middle warmer has, in row, has benefit, is the key medicine in blood.Thereby it can be enriched blood, can invigorate blood circulation again, both can stimulate the menstrual flow, again can be active.All menoxenias, dysmenorrhea, blood deficiency amenorrhea, shallow complexion, weak anemia, metrorrhagia, postnatal blood stasis, example, through women's such as (during menstrual onsets, occur mouth and nose bleed) commonly encountered diseases, can be used angelica for treating.
Semen Cuscutae in the > > of < < Sheng Nong's herbal classic, be listed in top grade return through: abnormal smells from the patient is pungent, sweet, flat nontoxic.[function with cure mainly]: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.The waist knee joint muscles and bones that is applicable to deficiency of the liver and kindey is ached, the diseases such as legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf and women's leukorrhagia, habitual abortion.
Fructus Lycii, cures mainly nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.In Fructus Lycii, contain 14 seed amino acids, and contain the special dietary compositions such as betanin, beautiful another name for Sichuan Province flavin, physalin, make it have outstanding health-care effect.
Summary of the invention
The object of the invention is to overcome the defect that prior art exists, a kind of Placenta Hominis activity enrich blood soft capsule and production technology thereof are provided, it is main that the present invention adopts Placenta Hominis, be aided with Radix Angelicae Sinensis, Semen Cuscutae and Fructus Lycii and carry out compatibility, the kidney invigorating and essence nourishing and the benefiting QI and nourishing blood effect of Placenta Hominis are strengthened greatly, not yet find that there is at present with Placenta Hominis master, with Radix Angelicae Sinensis, Semen Cuscutae and Fructus Lycii, carry out compatibility, patented technology and the relevant report of the active soft capsule of enriching blood of preparation.
To achieve these goals, the technical solution used in the present invention is:
The Placenta Hominis activity soft capsule of enriching blood, according to the component of weight portion is: Placenta Hominis 6-10 part, Radix Angelicae Sinensis 2-4 part, Semen Cuscutae 3-5 part, Fructus Lycii 2-4 part, lecithin 2-4 part, capsule carrier 4-10 part.
As the further scheme of the present invention: the described Placenta Hominis activity soft capsule of enriching blood, according to the component of weight portion is: 8 parts of described Placenta Hominiss, 3 parts of Radix Angelicae Sinensis, 4 parts of Semen Cuscutae, 3 parts of Fructus Lycii, 3 parts, lecithin, 7 parts of capsule carriers.
As the further scheme of the present invention: described capsule carrier is wherein any of Semen sojae atricolor, Semen arachidis hypogaeae, Fructus Canarii albi.
The enrich blood production technology of soft capsule of described Placenta Hominis activity, comprises the following steps: Placenta Hominis, Radix Angelicae Sinensis, Semen Cuscutae and Fructus Lycii low temperature at 1～10 ℃ is rubbed, then ultrasonic treatment 30～50min; Vacuum lyophilization at-25～-35 ℃ again, makes medicated powder water content below 8%; Then at-15～-25 ℃, be ground into 400～600 order micropowders, add lecithin and soft capsule carrier, mixing and stirring, soft capsule fill pelleting, washes ball, dries, sterilizing, check, packing is made the Placenta Hominis activity soft capsule of enriching blood.
As the further scheme of the present invention: Placenta Hominis, Radix Angelicae Sinensis, Semen Cuscutae and Fructus Lycii low temperature at 5-6 ℃ is rubbed, then ultrasonic treatment 35-45min; Vacuum lyophilization at-28～-32 ℃ again, makes medicated powder water content at 5%-7%; Then at-18～-22 ℃, be ground into 450～550 order micropowders, add lecithin and soft capsule carrier, mixing and stirring, soft capsule fill pelleting, washes ball, dries, sterilizing, check, packing is made the Placenta Hominis activity soft capsule of enriching blood.
It is sample that health product " soft capsule " product on market is take in the present invention, in the technical foundation of existing lyophilizing production line, utilize advanced in the world " Vacuum Freezing & Drying Technology ", " the broken technology of low-temperature fine powder " and " low-temperature ultrasonic cracking technique " processing fresh raw material of Chinese medicine, changed the processing technique of traditional backwardness, realization is with the function technology upgrading innovation of the tcm product of advanced technology processing, Improving The Quality of Products and added value, form economic advantages.Solve the bioactive ingredients and the nutrient substance that how farthest to retain raw material of Chinese medicine, do not lose thermal sensitivity nutrient substance, retain the biological hologram active substance of tcm product, under cryogenic conditions, Crushing of Ultrafine mixes polar substances and fat-soluble solvent to make soft capsule product.
" ultrasonic treatment " technology of utilization is extracted fresh Chinese medicine and Chinese medicine tire, become the liquid that contains a large amount of plurality of active ingredients such as micromolecule polypeptide, bioactive ingredients can be fine remain, separation and Extraction goes out effective ingredient wherein and makes the extraction and application rate of effective ingredient improve approximately 30 times (2～5% rise to more than 70%) than existing routine techniques fully.Its innovation point is: utilize ultrasonic cavitation effect, mechanical vibration, disturbance effect, high acceleration, emulsifying, spread, smash and the multistage effects such as stirring action, increase molecular motion of material frequency and speed, increase solvent penetration power, thereby accelerate target component and enter solvent, promote to extract and carry out, can avoid the destruction of high temperature to target component.
" Vacuum Freezing & Drying Technology " its know-why is: by the good tcm product quick freezing Cheng Bing of pretreatment, then under high vacuum condition, make water constantly be sublimed into outside gas discharge system, thereby make tcm product reach the object of dehydrate.Its innovation point is: the whole process of this technology remains under low temperature state material, and the product active ingredient processing is high, and nutrition does not run off, and processes time saving and energy savingly, with high content of technology, and convenient transportation, is convenient to long term storage.
The know-why of " the broken technology of low-temperature fine powder " is: the tcm product that pretreatment is good carries out Cellular Level Pulverizing under low-temperature material condition.Utilize " the broken technology of low-temperature fine powder " that the raw materials such as Chinese medicine are pulverized under cryogenic conditions, cell wall breaking active substance is discharged, reduced processing link, kept original nutrition not lose, greatly improved the bioavailability of product.The innovative point of technology is: traditional crushing technology is to carry out under normal condition, the impact that many nutrient substance can be subject to temperature loss and destruction in various degree, process powder particle size is only 80～100 orders simultaneously, and " freeze grinding technology " can make fine powder reach 200～1000 orders, make the particle diameter of powder body reach 1-0.3 μ m, crushing biological cells rate reaches more than 95%, has improved the bioavailability of product, makes its active component more easily for human body absorbs.
The active substance containing in solid-state intermediate is pulverized according to conventional grinding mode, the temperature producing during due to pulverizing is destroyed active component, and the conventional granularity of pulverizing is larger, mix, easily occur that with soft capsule carrier (mostly being lipid material) the immiscible layering of profit mixes inhomogeneous phenomenon, therefore we will consider application " low-temperature fine powder is broken " technology, plan is crushed to microgranule more than 300-800 order by solid-state intermediate, make it be easy to be blended in soft capsule carrier, form uniform suspension, make product content even.The determining of soft capsule carrier components, raw material and the soft capsule carrier proportioning of writing out a prescription will be research emphasis.
Compared with prior art, beneficial effect of the present invention is: it is main adopting Placenta Hominis, be aided with Radix Angelicae Sinensis, Semen Cuscutae and Fructus Lycii and carry out compatibility, the kidney invigorating and essence nourishing and the benefiting QI and nourishing blood effect of Placenta Hominis are strengthened greatly, not yet find that there is at present with Placenta Hominis master, with Radix Angelicae Sinensis, Semen Cuscutae and Fructus Lycii, carry out compatibility, patented technology and the relevant report of the active soft capsule of enriching blood of preparation.
The specific embodiment
Below in conjunction with the specific embodiment, technical scheme of the present invention is described further.
Embodiment 1
The Placenta Hominis activity soft capsule of enriching blood, is made by the raw material of following portions by weight proportioning: 6 parts of Placenta Hominiss, 2 parts of Radix Angelicae Sinensis, 3 parts of Semen Cuscutae, 2 parts of Fructus Lycii, 2 parts, lecithin, 4 parts of capsule carriers.The enrich blood production technology of soft capsule of described Placenta Hominis activity, comprises the following steps: Placenta Hominis, Radix Angelicae Sinensis, Semen Cuscutae and Fructus Lycii low temperature at 1 ℃ is rubbed, then ultrasonic treatment 30min; Vacuum lyophilization at-25 ℃ again, makes medicated powder water content below 8%; Then at-15 ℃, be ground into 400 order micropowders, add lecithin and soft capsule carrier, mixing and stirring, soft capsule fill pelleting, washes ball, dries, sterilizing, check, packing is made the Placenta Hominis activity soft capsule of enriching blood.
Embodiment 2
The Placenta Hominis activity soft capsule of enriching blood, is made by the raw material of following portions by weight proportioning: 8 parts of Placenta Hominiss, 3 parts of Radix Angelicae Sinensis, 4 parts of Semen Cuscutae, 3 parts of Fructus Lycii, 3 parts, lecithin, 7 parts of capsule carriers.The enrich blood production technology of soft capsule of described Placenta Hominis activity, comprises the following steps: Placenta Hominis, Radix Angelicae Sinensis, Semen Cuscutae and Fructus Lycii low temperature at 5 ℃ is rubbed, then ultrasonic treatment 40min; Vacuum lyophilization at-30 ℃ again, makes medicated powder water content below 8%; Then at-20 ℃, be ground into 500 order micropowders, add lecithin and soft capsule carrier, mixing and stirring, soft capsule fill pelleting, washes ball, dries, sterilizing, check, packing is made the Placenta Hominis activity soft capsule of enriching blood.
Embodiment 3
The Placenta Hominis activity soft capsule of enriching blood, is made by the raw material of following portions by weight proportioning: 10 parts of Placenta Hominiss, 4 parts of Radix Angelicae Sinensis, 5 parts of Semen Cuscutae, 4 parts of Fructus Lycii, 4 parts, lecithin, 10 parts of capsule carriers.The enrich blood production technology of soft capsule of described Placenta Hominis activity, comprises the following steps: Placenta Hominis, Radix Angelicae Sinensis, Semen Cuscutae and Fructus Lycii low temperature at 10 ℃ is rubbed, then ultrasonic treatment 50min; Vacuum lyophilization at-35 ℃ again, makes medicated powder water content below 8%; Then at-25 ℃, be ground into 600 order micropowders, add lecithin and soft capsule carrier, mixing and stirring, soft capsule fill pelleting, washes ball, dries, sterilizing, check, packing is made the Placenta Hominis activity soft capsule of enriching blood.
The above; it is only the preferably specific embodiment of the present invention; protection scope of the present invention is not limited to this; anyly be familiar with those skilled in the art; in the technical scope disclosing in the present invention, the simple transformation of the technical scheme that can obtain apparently or equivalence are replaced and are all fallen within the scope of protection of the present invention.
Claims (5)
1. the Placenta Hominis activity soft capsule of enriching blood, is characterized in that, is: Placenta Hominis 6-10 part, Radix Angelicae Sinensis 2-4 part, Semen Cuscutae 3-5 part, Fructus Lycii 2-4 part, lecithin 2-4 part, capsule carrier 4-10 part according to the component of weight portion.
2. the Placenta Hominis activity according to claim 1 soft capsule of enriching blood, it is characterized in that, the described Placenta Hominis activity soft capsule of enriching blood, according to the component of weight portion is: 8 parts of described Placenta Hominiss, 3 parts of Radix Angelicae Sinensis, 4 parts of Semen Cuscutae, 3 parts of Fructus Lycii, 3 parts, lecithin, 7 parts of capsule carriers.
3. the Placenta Hominis activity according to claim 1 soft capsule of enriching blood, is characterized in that, described capsule carrier is wherein any of Semen sojae atricolor, Semen arachidis hypogaeae, Fructus Canarii albi.
4. the described Placenta Hominis activity of one of the claim 1-3 production technology for soft capsule of enriching blood, comprises the following steps: Placenta Hominis, Radix Angelicae Sinensis, Semen Cuscutae and Fructus Lycii low temperature at 1～10 ℃ is rubbed, then ultrasonic treatment 30～50min; Vacuum lyophilization at-25～-35 ℃ again, makes medicated powder water content below 8%; Then at-15～-25 ℃, be ground into 400～600 order micropowders, add lecithin and soft capsule carrier, mixing and stirring, soft capsule fill pelleting, washes ball, dries, sterilizing, check, packing is made the Placenta Hominis activity soft capsule of enriching blood.
5. the Placenta Hominis activity according to claim 4 production technology of soft capsule of enriching blood, is characterized in that, Placenta Hominis, Radix Angelicae Sinensis, Semen Cuscutae and Fructus Lycii low temperature at 5-6 ℃ is rubbed, then ultrasonic treatment 35-45min; Vacuum lyophilization at-28～-32 ℃ again, makes medicated powder water content at 5%-7%; Then at-18～-22 ℃, be ground into 450～550 order micropowders, add lecithin and soft capsule carrier, mixing and stirring, soft capsule fill pelleting, washes ball, dries, sterilizing, check, packing is made the Placenta Hominis activity soft capsule of enriching blood.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103784602A (en) * | 2014-01-18 | 2014-05-14 | 刘斌胜 | Traditional Chinese medicine for treating iron-deficiency anemia |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784602A (en) * | 2014-01-18 | 2014-05-14 | 刘斌胜 | Traditional Chinese medicine for treating iron-deficiency anemia |
Non-Patent Citations (5)
| Title |
|---|
| 王国华: "《简明中药临床手册》", 28 February 2005 * |
| 袁长季: "《中医药学概论》", 30 June 2012 * |
| 谢艳华等: "紫参血康片对贫血小鼠的补血作用", 《陕西中医》 * |
| 邬御飞等: "补肾养经汤对雌性去势大鼠白细胞介素-2和白细胞介素-8含量的影响", 《时珍国医国药》 * |
| 马缠过等: "鸡血藤升白汤对放疗引起的小鼠骨髓抑制的影响", 《现代肿瘤医学》 * |
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