CN104188887A - Whitening composition and application thereof - Google Patents

Whitening composition and application thereof Download PDF

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Publication number
CN104188887A
CN104188887A CN201410515491.3A CN201410515491A CN104188887A CN 104188887 A CN104188887 A CN 104188887A CN 201410515491 A CN201410515491 A CN 201410515491A CN 104188887 A CN104188887 A CN 104188887A
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China
Prior art keywords
skin
whitening
gorgonian
oil
nicotiamide
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CN201410515491.3A
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Chinese (zh)
Inventor
邓玉川
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GUANGDONG ZHENLIS COSMETICS Co Ltd
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GUANGDONG ZHENLIS COSMETICS Co Ltd
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Priority to CN201410515491.3A priority Critical patent/CN104188887A/en
Publication of CN104188887A publication Critical patent/CN104188887A/en
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Abstract

The invention discloses a whitening composition and the application thereof in whitening cosmetics. The whitening composition contains the following components in weight percentage: 1-10% of lipid soluble VC derivatives, 0.05-0.2% of Glabridin, 1-5% of nicotinamide, 1-5% of hydrogenated soya lecithin, 0.1-0.5% of a gorgonia extracting solution and 0.5-2% of an amino-acid humectant. According to the whitening composition prepared by the invention, the whitening and speckle removing effects are obvious, the whitening composition can be quickly adsorbed by skin, the irritation to the skin is weak and the obvious moisture-holding, anti-inflammatory and antiallergic effects and effective skin brightening effect are realized.

Description

A kind of lightening compositions and application thereof
Technical field
The present invention relates to a kind of lightening compositions and application thereof.
Background technology
Nails is always advocated the skin whitening of " skin is as snow, solidifying as fat ", and whitening is almost the target that all Nails are seek assiduously, thereby skin-lightening cosmetic occupies an important position at Cosmetic Market always.And client's pursuit military order whitening product development upgrades.
All the time, whitening and speckle dispelling is all the topic that people earnestly pay close attention to.People wish to obtain pale bright and clean skin by the use of whitening nursing product, more have some to utilize functional type skin-lightening cosmetic to alleviate the pigmentation such as senile plaque, chloasma.
Should be based upon on the basis that whitening mechanism is understood in depth the development and application of whitening agent, and dermal melanin inhibition mechanism is the centre point of whitening mechanism, therefore, it is primary understanding melanic generation reason and principle.First, the reason that causes dermal melanin to generate has multiple, as environmental factorss such as ultraviolet, waste gas, active oxygens.Even some food is also the seed of trouble of skin darkening, as the food that is rich in the metals such as copper ferrum zinc easily makes people's skin darkening, this is because these metals can increase the quantity that generates the material such as relevant tryrosinase and DOPA quinone with melanin directly or indirectly with active.Many medicines also can change the normal colour of skin, as chloroquine is strong especially to melanic affinity, can increases the weight of the many diseases of colour of skin blackening and also can change the normal colour of skin, make its blackening.And some disease, as abnormal in dystrophic disease, vivo oxidation and antioxidation dysequilibrium, endocrine disturbance, Dysbiosis, metabolism disorder, body trace element content etc., also can change the normal colour of skin.
Secondly, the synthetic key step of dermal melanin is: synthetic and activity, melanosome storage, the melanocyte of the picked-up of tyrosine and distribution, tryrosinase and melanin granule melanin granule being transported in epithelial cells, epithelial cells by melanocyte dendron move with epidermis cell, follows cuticular coming off and discharges.In melanin building-up process, be subject to being permitted multifactorial impact, be first the activity of tryrosinase, this enzyme is the oxidase of cupric, its activity is associated with content of copper ion, and in body, the change of biochemical process and physical environment, can exert an influence to the activity of tryrosinase.From tyrosine to DOPA, conversion and DOPA transform to DOPA quinone, are all undertaken by tyrosinase catalysis, and tryrosinase is directly being controlled the synthetic initial and speed of melanin, has determined whether subsequent step can go on.In the time that various factors acts on tryrosinase and makes its active rising, melanin is synthetic to be increased, and in the time that tyrosinase activity is suppressed, melanin is synthetic to be reduced.
Utilize generation and the activity of restraint of tyrosinase, thereby disturb or hinder melanic generation or disturb melanin biochemical reaction process, make its reaction generate certain intermediate, generate melanic principle and can not complete reaction, on market, occurred many whitening class skin care item.But the infiltration rate of some whitening class skin care item on skin is slow, can not meets youngster and realize the skin needs of maintenance fast; Simultaneously on the market some whitening class skin care item large to the stimulation of skin, easily cause skin allergy while using, not only can not play the effect of maintenance nursing skin, on the contrary skin has been caused to injury; Meanwhile, after some whitening and skin-protecting product uses, skin is easily impaired, although skin bleaches, lasting use can be accelerated skin aging, though make whiteness of skin matt.
Summary of the invention
The invention provides a kind of lightening compositions, adopt oil-soluble VC derivant, the pyridine of light Radix Glycyrrhizae, nicotiamide, hydrogenated soy phosphatidyl choline, gorgonian extracting solution, amino acid humectant to solve in prior art whitening class skin care item by combination not remarkable in whitening, speckle dispelling, bright skin effect, the poor technical problem of effect aspect moisturizing, antiinflammatory, antiallergic.
Object of the present invention is achieved through the following technical solutions:
A kind of lightening compositions, the consumption (by weight percentage) of the raw material components containing in its formula is as follows:
Oil-soluble VC derivant 1~10%,
Light Radix Glycyrrhizae pyridine 0.05~0.2%,
Nicotiamide 1~5%,
Hydrogenated soy phosphatidyl choline 1~5%,
Gorgonian extracting solution 0.1~0.5%,
Amino acid humectant 0.5~2%.
Its formula of a kind of lightening compositions of the present invention is made up of following raw material (by weight percentage): glycerol 4~8%, polydimethyl siloxane fluid 1~3%, hexadeca-octadecyl alcohol 1~5%, vitamin E 0.5~1.5%, HANSHENGJIAO 0.1~0.3%, phenoxyethanol 0.2~0.4%, Sensiva SC50 0.03~0.08%, hydrogenated polydecene 4~8%, oil-soluble VC derivant 1~10%, light Radix Glycyrrhizae pyridine 0.05~0.2%, nicotiamide 1~5%, hydrogenated soy phosphatidyl choline 1~5%, gorgonian extracting solution 0.1~0.5%, amino acid humectant 0.5~2%, surplus is water.Wherein, gorgonian extracting solution is a kind of extract of marine source of pure natural.Gorgonian can obtain from the Atlantic Ocean.Gorgonian extract can be first infiltrates gorgonian by butanediol or caprylic/capric triglyceride or pentanediol, then extracts purification and obtains.An active component in gorgonian extract is class pterosin (or being pseudopterosin), and class pterosin is proved to be effective anti-inflammatory activity mixture.
Preferably, in formula, the consumption of each raw material components is as follows by weight percentage: glycerol 5~7%, polydimethyl siloxane fluid 1.5~2.5%, hexadeca-octadecyl alcohol 2~4%, vitamin E 0.7~1.3%, HANSHENGJIAO 0.15~0.25%, phenoxyethanol 0.25~0.35%, Sensiva SC50 0.04~0.07%, hydrogenated polydecene 5~7%, oil-soluble VC derivant 2~9%, light Radix Glycyrrhizae pyridine 0.07~0.15%, nicotiamide 2~4%, hydrogenated soy phosphatidyl choline 2~4%, gorgonian extracting solution 0.2~0.4%, amino acid humectant 0.7~1.5%, surplus is water.
Preferably, in formula, the consumption of each raw material components is as follows by weight percentage: glycerol 5~6%, polydimethyl siloxane fluid 1.5~2%, hexadeca-octadecyl alcohol 3~4%, vitamin e1~1.2%, HANSHENGJIAO 0.15~0.2%, phenoxyethanol 0.3~0.35%, Sensiva SC50 0.05~0.06%, hydrogenated polydecene 5~6%, oil-soluble VC derivant 4~8%, light Radix Glycyrrhizae pyridine 0.09~0.13%, nicotiamide 2.5~3.5%, hydrogenated soy phosphatidyl choline 3~4%, gorgonian extracting solution 0.3~0.4%, amino acid humectant 0.9~1.5%, surplus are water.
Described a kind of lightening compositions is applied in skin-whitening skin protection, does not limit to and applies in the whitening and skin-protectings such as skin whitener, cleawhite pack, whitening emulsion, whitening Cleansing Foam, UV white whitening toner.
Owing to having adopted technique scheme, beneficial effect of the present invention is as follows:
1, lightening compositions whitening, speckle dispelling, the bright skin effect that prepared by the present invention are remarkable.
Oil-soluble VC derivant, the pyridine of light Radix Glycyrrhizae and nicotiamide in this lightening compositions, generally speaking, the effectively activity of restraint of tyrosinase, dopachrome interconvertible enzyme, thus melanin generation reduced in a large number, reach the remarkable result of whitening, speckle dispelling.Because oil-soluble VC derivant, it has excellent percutaneous absorbability, can effectively suppress the activity of intracellular tyrosine enzyme, the effectively generation of check melanin, and prevention lipid oxidation and skin aging, reduce cell injury and DNA damage due to UV.For nicotiamide, its most important effect is colour of skin dimness, the jaundice that alleviates and prevent skin to produce in aging course in early days, also can repair impaired Stratum corneum lipids barrier, improves skin resistance.For the pyridine of light Radix Glycyrrhizae, there are significant inhibitory enzyme activity and Antioxidation in vitro, may be the rate-limiting enzyme generating by check melanin---tryrosinase and the effect of removing free radical.In conjunction with formula of the present invention, particularly oil-soluble VC derivant and nicotiamide, can reach the effect of speckle dispelling, whitening, bright skin and antiinflammatory, and have no side effect.
2, the lightening compositions that prepared by the present invention absorbs soon, does not stimulate.
In this lightening compositions, hydrogenated soy phosphatidyl choline is derived from natural; after hydrogenation, obtain higher stability; its effect shows: it is natural emulsifying agent; play and can promote skin to absorb fast nutrient substance; in conjunction with formula of the present invention; can play and strengthen moistening effect and reduce lightening compositions to skin irritant effect, and skin is had no side effect, can effectively protect skin.
3, lightening compositions antiinflammatory, the antiallergic effect that prepared by the present invention are good.
In this lightening compositions, gorgonian extract, amino acid humectant can significantly play moisturizing, antiinflammatory, antianaphylactic effect generally.Wherein: gorgonian extracting solution is rich in class pterosin, be a kind of anti-inflammatory composition of efficiency natural, can prevent and offset the stimulation of outer bound pair skin.Amino acid humectant, can provide gentle replenishing water and preserving moisture effect, is the basis that skin is set up barrier function, is whitening, antiinflammatory, the basis of reparation.
The various compositions of lightening compositions, especially the rational proportion of oil-soluble VC derivant, the pyridine of light Radix Glycyrrhizae, nicotiamide, hydrogenated soy phosphatidyl choline, gorgonian extracting solution and amino acid humectant, and with the good compatibility of skin, make its working substance bring into play more effective effect; In this lightening compositions, each composition has played the effect of combined effect, Synergistic simultaneously, can reach the function of best whitening, light speckle, the brightening colour of skin, lacks any composition, all can make the comprehensive effect of effect decline to some extent.
Detailed description of the invention
In order to make object of the present invention, technical scheme and advantage clearer, below in conjunction with embodiment, the present invention is further elaborated, but the scope of protection of present invention is not limited to the scope that embodiment expresses.
Embodiment 1
In the present embodiment, the each component of lightening compositions and content (by weight percentage) are as follows:
Glycerol 8%, polydimethyl siloxane fluid 3%, hexadeca-octadecyl alcohol 5%, vitamin e1 .5%, HANSHENGJIAO 0.3%, phenoxyethanol 0.4%, Sensiva SC50 0.08%, hydrogenated polydecene 8%, oil-soluble VC derivant 10%, light Radix Glycyrrhizae pyridine 0.2%, nicotiamide 5%, hydrogenated soy phosphatidyl choline 5%, gorgonian extracting solution 0.5%, amino acid humectant 2%, surplus are water.
Applied in whitening and skin-protecting according to the formula of the present embodiment 1 lightening compositions, the method for preparing skin whitener is as follows:
(1) hexadeca-octadecyl alcohol, hydrogenated polydecene, polydimethyl siloxane fluid, vitamin E, oil-soluble VC derivant are added successively in oil phase reactor and be heated to 80 DEG C;
(2) deionized water, HANSHENGJIAO, nicotiamide are added to aqueous phase reactions still, be heated with stirring to 80 DEG C, oil phase part is joined to aqueous phase reactions still, mixing stirs evenly;
(3) after hydrogenated soy phosphatidyl choline being disperseed evenly by suitable quantity of water, add aqueous phase reactions still, after the pyridine of light Radix Glycyrrhizae is disperseed with glycerol, add aqueous phase reactions still, vacuum high speed homogenization emulsifying 5 minutes, stirs cooling;
(4) in the time of 40 DEG C, amino acid humectant, gorgonian extracting solution, phenoxyethanol, Sensiva SC50 are added to reactor successively, continue stirring and be cooled to room temperature.The product preparing is skin whitener, and is labeled as sample 1.
Skin whitener (being labeled as sample 1) prepared by the present embodiment 1 and commercially available common skin-lightening cosmetic (Nivea skin whitener, be labeled as sample 2) after continuing to try out for 3 months, human body skin carries out melanin content contrast respectively, adopt the MX18 melanin tester of German CK company to detect melanin content, concrete condition sees the following form 1.
Table 1 trier uses the melanin content value recording after skin whitener
Use the melanin content of sample 1 and sample 2 front skins to be 500, continued to use after sample 1 and sample 2 through 3 months, test result finds to use sample 1 to have obvious reduction with respect to the melanin content of sample 2 skins, and the better effects if of the more common skin whitener of whitening effect of the prepared skin whitener of the present embodiment 1 is described.
Embodiment 2
In the present embodiment, each component of lightening compositions and content (by weight percentage) are as follows:
Glycerol 4%, polydimethyl siloxane fluid 1%, hexadeca-octadecyl alcohol 1%, vitamin E 0.5%, HANSHENGJIAO 0.1%, phenoxyethanol 0.2%, Sensiva SC50 0.03%, hydrogenated polydecene 4%, oil-soluble VC derivant 1%, light Radix Glycyrrhizae pyridine 0.05%, nicotiamide 1%, hydrogenated soy phosphatidyl choline 1%, gorgonian extracting solution 0.1%, amino acid humectant 0.5%, surplus are water.
Applied in whitening and skin-protecting according to the formula of the present embodiment 2 lightening compositions, the method for preparing cleawhite pack is as follows:
(1) hexadeca-octadecyl alcohol, hydrogenated polydecene, polydimethylsiloxane, vitamin E, oil-soluble VC derivant are added successively in oil phase reactor and be heated to 80 DEG C;
(2) deionized water, HANSHENGJIAO, nicotiamide are added to aqueous phase reactions still, be heated with stirring to 80 DEG C, oil phase part is joined to aqueous phase reactions still, mixing stirs evenly;
(3) after hydrogenated soy phosphatidyl choline being disperseed evenly by suitable quantity of water, add aqueous phase reactions still, after the pyridine of light Radix Glycyrrhizae is disperseed with glycerol, add aqueous phase reactions still, vacuum high speed homogenization emulsifying 5 minutes, stirs cooling;
(4) in the time of 40 DEG C, amino acid humectant, gorgonian extracting solution, phenoxyethanol, Sensiva SC50 are added to reactor successively, continue stirring and be cooled to room temperature.
Cleawhite pack prepared by the present embodiment 2 applies to whitening and skin-protecting, finds: CHENNU scholar, 32 years old, the cleawhite pack front face that uses the present embodiment to prepare had chloasma, to whitening class skin care item allergy.Use described product cleawhite pack half a year, the chloasma of face is slightly desalinated, and not irritated to whitening class skin care item; Use described product after 1 month, chloasma is obviously thin out; Continue to use after 3 months, the chloasma of face is not easy to find out by naked eyes, and the overall brightening of the colour of skin, can rubescently not itch.
Embodiment 3
In the present embodiment 3, the each component of lightening compositions and content (by weight percentage) are as follows:
Glycerol 6%, polydimethyl siloxane fluid 2%, hexadeca-octadecyl alcohol 3%, vitamin e1 %, HANSHENGJIAO 0.2%, phenoxyethanol 0.3%, Sensiva SC50 0.05%, hydrogenated polydecene 6%, oil-soluble VC derivant 5%, light Radix Glycyrrhizae pyridine 0.13%, nicotiamide 3%, hydrogenated soy phosphatidyl choline 3.5%, gorgonian extracting solution 0.35%, amino acid humectant 1.2%, surplus are water.
Applied in whitening and skin-protecting according to the formula of the present embodiment 3 lightening compositions, the method for preparing whitening emulsion is as follows:
(1) hexadeca-octadecyl alcohol, hydrogenated polydecene, polydimethyl siloxane fluid, vitamin E, oil-soluble VC derivant are added successively in oil phase reactor and be heated to 80 DEG C;
(2) deionized water, HANSHENGJIAO, nicotiamide are added to aqueous phase reactions still, be heated with stirring to 80 DEG C, oil phase part is joined to aqueous phase reactions still, mixing stirs evenly;
(3) after hydrogenated soy phosphatidyl choline being disperseed evenly by suitable quantity of water, add aqueous phase reactions still, after the pyridine of light Radix Glycyrrhizae is disperseed with glycerol, add aqueous phase reactions still, vacuum high speed homogenization emulsifying 5 minutes, stirs cooling;
(4) in the time of 40 DEG C, amino acid humectant, gorgonian extracting solution, phenoxyethanol, Sensiva SC50 are added to reactor successively, continue stirring and be cooled to room temperature.
Whitening emulsion prepared by embodiment 3 applies to whitening and skin-protecting, finds: Mrs Zhou, and 40 years old, face below had chloasma, top to have day sunburn, and the overall colour of skin is obscure, and skin quality is partially dry, and skin easily causes inflammation.Use whitening emulsion after 4 weeks, day sunburn and chloasma are all desalinated, and the colour of skin improves; Continue to use 8 weeks, day sunburn and chloasma color are obviously thin out, of pink and healthy-looking glossy; Use after 12 weeks the symptom such as that skin there will not be is scratchy, pruritus.
The announcement of book and instruction according to the above description, those skilled in the art in the invention can also change and revise above-mentioned embodiment.Therefore, the present invention is not limited to detailed description of the invention disclosed and described above, also should fall in the protection domain of claim of the present invention modifications and changes more of the present invention.In addition,, although used some specific terms in this description, these terms just for convenience of description, do not form any restriction to the present invention.

Claims (6)

1. a lightening compositions, is characterized in that, comprises by weight percentage following component:
Oil-soluble VC derivant 1~10%,
Light Radix Glycyrrhizae pyridine 0.05~0.2%,
Nicotiamide 1~5%,
Hydrogenated soy phosphatidyl choline 1~5%,
Gorgonian extracting solution 0.1~0.5%,
Amino acid humectant 0.5~2%.
2. a kind of lightening compositions according to claim 1, it is characterized in that, it comprises following component by weight percentage: glycerol 4~8%, polydimethyl siloxane fluid 1~3%, hexadeca-octadecyl alcohol 1~5%, vitamin E 0.5~1.5%, HANSHENGJIAO 0.1~0.3%, phenoxyethanol 0.2~0.4%, Sensiva SC50 0.03~0.08%, hydrogenated polydecene 4~8%, oil-soluble VC derivant 1~10%, light Radix Glycyrrhizae pyridine 0.05~0.2%, nicotiamide 1~5%, hydrogenated soy phosphatidyl choline 1~5%, gorgonian extracting solution 0.1~0.5%, amino acid humectant 0.5~2%, surplus is water.
3. a kind of lightening compositions according to claim 1 and 2, it is characterized in that, comprise by weight percentage following component: glycerol 5~7%, polydimethyl siloxane fluid 1.5~2.5%, hexadeca-octadecyl alcohol 2~4%, vitamin E 0.7~1.3%, HANSHENGJIAO 0.15~0.25%, phenoxyethanol 0.25~0.35%, Sensiva SC50 0.04~0.07%, hydrogenated polydecene 5~7%, oil-soluble VC derivant 2~9%, light Radix Glycyrrhizae pyridine 0.07~0.15%, nicotiamide 2~4%, hydrogenated soy phosphatidyl choline 2~4%, gorgonian extracting solution 0.2~0.4%, amino acid humectant 0.7~1.5%, surplus is water.
4. a kind of lightening compositions according to claim 1 and 2, it is characterized in that, comprise by weight percentage following component: glycerol 5~6%, polydimethyl siloxane fluid 1.5~2%, hexadeca-octadecyl alcohol 3~4%, vitamin E 1~1.2%, HANSHENGJIAO 0.15~0.2%, phenoxyethanol 0.3~0.35%, Sensiva SC50 0.05~0.06%, hydrogenated polydecene 5~6%, oil-soluble VC derivant 4~8%, light Radix Glycyrrhizae pyridine 0.09~0.13%, nicotiamide 2.5~3.5%, hydrogenated soy phosphatidyl choline 3~4%, gorgonian extracting solution 0.3~0.4%, amino acid humectant 0.9~1.5%, surplus is water.
5. the application of a kind of lightening compositions claimed in claim 1 in Skin whitening care cosmetics.
6. application according to claim 5, is characterized in that: described Skin whitening care cosmetics is skin whitener, whitening emulsion, whitening Cleansing Foam, UV white whitening toner or cleawhite pack.
CN201410515491.3A 2014-09-29 2014-09-29 Whitening composition and application thereof Pending CN104188887A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784074A (en) * 2015-04-01 2015-07-22 珀莱雅化妆品股份有限公司 Cationic nano emulsion with anti-allergic effect and preparation method of cationic nano emulsion
CN105902423A (en) * 2016-04-15 2016-08-31 欧标(广州)化妆品有限公司 Whitening mask composition for uniformizing skin color and brightening skin
CN111317707A (en) * 2020-04-28 2020-06-23 厦门羸利康实业有限公司 Gorgonia pseudopterogorgia hydrating and moisturizing mask and preparation method thereof
CN111450008A (en) * 2020-04-30 2020-07-28 广州天玺生物科技有限公司 Whitening cream and preparation method thereof

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CN103284897A (en) * 2012-01-27 2013-09-11 玫琳凯有限公司 Cosmetic formulation
CN103432009A (en) * 2013-09-12 2013-12-11 广东轻工职业技术学院 Whitening agent liposome coating micro-capsule composition as well as preparation method and application thereof
CN103550135A (en) * 2013-11-08 2014-02-05 广州栋方日化有限公司 Whitening composition and cosmetic

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103284897A (en) * 2012-01-27 2013-09-11 玫琳凯有限公司 Cosmetic formulation
CN103040692A (en) * 2012-11-15 2013-04-17 北京一轻研究院 Composition for whitening skin
CN103432009A (en) * 2013-09-12 2013-12-11 广东轻工职业技术学院 Whitening agent liposome coating micro-capsule composition as well as preparation method and application thereof
CN103550135A (en) * 2013-11-08 2014-02-05 广州栋方日化有限公司 Whitening composition and cosmetic

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784074A (en) * 2015-04-01 2015-07-22 珀莱雅化妆品股份有限公司 Cationic nano emulsion with anti-allergic effect and preparation method of cationic nano emulsion
CN104784074B (en) * 2015-04-01 2017-11-28 珀莱雅化妆品股份有限公司 A kind of cation nanometer emulsion with antiallergic effect and preparation method thereof
CN105902423A (en) * 2016-04-15 2016-08-31 欧标(广州)化妆品有限公司 Whitening mask composition for uniformizing skin color and brightening skin
CN111317707A (en) * 2020-04-28 2020-06-23 厦门羸利康实业有限公司 Gorgonia pseudopterogorgia hydrating and moisturizing mask and preparation method thereof
CN111450008A (en) * 2020-04-30 2020-07-28 广州天玺生物科技有限公司 Whitening cream and preparation method thereof

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Application publication date: 20141210