CN1041627C - (s)－2,2,2－三氯－n－(2－氯环己－2－烯基)－乙酰胺和(s)－2－氯环己－2－烯胺 - Google Patents
(s)－2,2,2－三氯－n－(2－氯环己－2－烯基)－乙酰胺和(s)－2－氯环己－2－烯胺 Download PDFInfo
- Publication number
- CN1041627C CN1041627C CN94194207A CN94194207A CN1041627C CN 1041627 C CN1041627 C CN 1041627C CN 94194207 A CN94194207 A CN 94194207A CN 94194207 A CN94194207 A CN 94194207A CN 1041627 C CN1041627 C CN 1041627C
- Authority
- CN
- China
- Prior art keywords
- oxo
- acid
- dioxo
- dihydro
- pyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
- C07C211/40—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/14—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15597293A | 1993-11-19 | 1993-11-19 | |
| US08/155972 | 1993-11-19 | ||
| US08155,972 | 1993-11-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1135217A CN1135217A (zh) | 1996-11-06 |
| CN1041627C true CN1041627C (zh) | 1999-01-13 |
Family
ID=22557529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN94194207A Expired - Fee Related CN1041627C (zh) | 1993-11-19 | 1994-10-20 | (s)－2,2,2－三氯－n－(2－氯环己－2－烯基)－乙酰胺和(s)－2－氯环己－2－烯胺 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US5502253A (OSRAM) |
| EP (1) | EP0729456B1 (OSRAM) |
| JP (1) | JP3547749B2 (OSRAM) |
| KR (1) | KR100310592B1 (OSRAM) |
| CN (1) | CN1041627C (OSRAM) |
| AT (1) | ATE161251T1 (OSRAM) |
| AU (1) | AU683956B2 (OSRAM) |
| CA (1) | CA2177044C (OSRAM) |
| DE (1) | DE69407430T2 (OSRAM) |
| DK (1) | DK0729456T3 (OSRAM) |
| ES (1) | ES2112034T3 (OSRAM) |
| FI (1) | FI962045A7 (OSRAM) |
| GR (1) | GR3025899T3 (OSRAM) |
| HU (1) | HU220895B1 (OSRAM) |
| IL (1) | IL111656A (OSRAM) |
| NO (1) | NO309269B1 (OSRAM) |
| NZ (1) | NZ275939A (OSRAM) |
| TW (1) | TW321638B (OSRAM) |
| WO (1) | WO1995014663A2 (OSRAM) |
| ZA (1) | ZA949030B (OSRAM) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8049732B2 (en) * | 2007-01-03 | 2011-11-01 | Apple Inc. | Front-end signal compensation |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0249223A2 (en) * | 1986-06-13 | 1987-12-16 | Merrell Dow Pharmaceuticals Inc. | Novel antihypertensive agent |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4608082A (en) * | 1985-02-19 | 1986-08-26 | Union Carbide Corporation | Herbicidal cycloalkenyl acetamides |
| US4973585A (en) * | 1986-06-13 | 1990-11-27 | Merrell Dow Pharmaceuticals | Tricyclic lactams active as antihypertensive agents |
| US4824832A (en) * | 1987-12-30 | 1989-04-25 | Merrell Dow Pharmaceuticals Inc. | Sulfhydryl containing tricyclic lactams and their pharmacological methods of use |
| US5430145A (en) * | 1990-10-18 | 1995-07-04 | Merrell Dow Pharmaceuticals Inc. | Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace |
-
1994
- 1994-10-20 NZ NZ275939A patent/NZ275939A/en not_active IP Right Cessation
- 1994-10-20 EP EP95900385A patent/EP0729456B1/en not_active Expired - Lifetime
- 1994-10-20 JP JP51506295A patent/JP3547749B2/ja not_active Expired - Fee Related
- 1994-10-20 AT AT95900385T patent/ATE161251T1/de active
- 1994-10-20 HU HU9601335A patent/HU220895B1/hu not_active IP Right Cessation
- 1994-10-20 CN CN94194207A patent/CN1041627C/zh not_active Expired - Fee Related
- 1994-10-20 KR KR1019960702648A patent/KR100310592B1/ko not_active Expired - Fee Related
- 1994-10-20 WO PCT/US1994/011941 patent/WO1995014663A2/en not_active Ceased
- 1994-10-20 FI FI962045A patent/FI962045A7/fi unknown
- 1994-10-20 DK DK95900385.6T patent/DK0729456T3/da active
- 1994-10-20 DE DE69407430T patent/DE69407430T2/de not_active Expired - Lifetime
- 1994-10-20 ES ES95900385T patent/ES2112034T3/es not_active Expired - Lifetime
- 1994-10-20 AU AU81225/94A patent/AU683956B2/en not_active Ceased
- 1994-10-20 CA CA002177044A patent/CA2177044C/en not_active Expired - Fee Related
- 1994-11-14 ZA ZA949030A patent/ZA949030B/xx unknown
- 1994-11-15 TW TW083110598A patent/TW321638B/zh not_active IP Right Cessation
- 1994-11-16 IL IL11165694A patent/IL111656A/xx not_active IP Right Cessation
-
1995
- 1995-03-30 US US08/415,028 patent/US5502253A/en not_active Expired - Lifetime
-
1996
- 1996-03-30 US US08/413,649 patent/US5508411A/en not_active Expired - Lifetime
- 1996-05-15 NO NO961999A patent/NO309269B1/no not_active IP Right Cessation
-
1998
- 1998-01-14 GR GR980400072T patent/GR3025899T3/el unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0249223A2 (en) * | 1986-06-13 | 1987-12-16 | Merrell Dow Pharmaceuticals Inc. | Novel antihypertensive agent |
Non-Patent Citations (1)
| Title |
|---|
| J,AM,CHEM,SUE,109(18) 1987.1.1 E.J.CORY等人,HIGH ENANTISELEEFIVE BORANE REDACFION OF KEFONES CATALGYE EL BES CATALGYEEL B * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995014663A3 (en) | 1995-08-17 |
| US5502253A (en) | 1996-03-26 |
| DE69407430D1 (de) | 1998-01-29 |
| WO1995014663A2 (en) | 1995-06-01 |
| JPH09505583A (ja) | 1997-06-03 |
| ES2112034T3 (es) | 1998-03-16 |
| CA2177044A1 (en) | 1995-06-01 |
| TW321638B (OSRAM) | 1997-12-01 |
| ZA949030B (en) | 1995-07-18 |
| KR100310592B1 (ko) | 2002-05-13 |
| AU683956B2 (en) | 1997-11-27 |
| NO961999L (no) | 1996-05-15 |
| AU8122594A (en) | 1995-06-13 |
| CA2177044C (en) | 1999-06-01 |
| GR3025899T3 (en) | 1998-04-30 |
| ATE161251T1 (de) | 1998-01-15 |
| NO309269B1 (no) | 2001-01-08 |
| JP3547749B2 (ja) | 2004-07-28 |
| DE69407430T2 (de) | 1998-04-09 |
| HU9601335D0 (en) | 1996-07-29 |
| IL111656A (en) | 1999-06-20 |
| NO961999D0 (no) | 1996-05-15 |
| CN1135217A (zh) | 1996-11-06 |
| IL111656A0 (en) | 1995-01-24 |
| NZ275939A (en) | 1997-04-24 |
| DK0729456T3 (da) | 1998-03-30 |
| US5508411A (en) | 1996-04-16 |
| HU220895B1 (en) | 2002-06-29 |
| EP0729456A1 (en) | 1996-09-04 |
| FI962045A0 (fi) | 1996-05-14 |
| EP0729456B1 (en) | 1997-12-17 |
| FI962045L (fi) | 1996-05-14 |
| FI962045A7 (fi) | 1996-05-14 |
| HUT74326A (en) | 1996-12-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR100426030B1 (ko) | 락톤계 당화합물에서의 키랄성 전환방법 | |
| CN1094927C (zh) | 2－氮杂二羟基二环[2.2.1]庚烷化合物的制备方法以及该化合物的l－酒石酸盐 | |
| CN1041627C (zh) | (s)－2,2,2－三氯－n－(2－氯环己－2－烯基)－乙酰胺和(s)－2－氯环己－2－烯胺 | |
| CN1311788A (zh) | (1H)－苯并[c]喹嗪－3－酮衍生物的合成方法 | |
| CN1104409C (zh) | 氨基四氢萘酮衍生物及其制备方法 | |
| CN86102630A (zh) | 制备7-氨基-3-丙烯基头孢素酸及其酯类的方法 | |
| CN101407460A (zh) | 三羟基-2-酰基苯乙酸酯及其制备方法与应用 | |
| EP1063232B1 (en) | Process for producing erythro-3-amino-2-hydroxybutyric acid derivatives | |
| CN1235607A (zh) | 由毒扁豆醚制备毒扁豆碱氨基甲酸酯衍生物的方法 | |
| US5380849A (en) | Process for optically pure decahydroisoqiunolines | |
| Mandville et al. | A New Stereo-and Enantioselective Approach to the N-Terminal Amino Acid Moiety of Nikkomycins B and BX | |
| CN1121383C (zh) | 地尔硫䓬合成的废产物的再利用方法 | |
| WO2012098563A2 (en) | One-pot preparation of cyclobenzaprine hydrochloride | |
| CN106674330A (zh) | 一种34-Dimethyl apratoxin A/E的制备方法 | |
| CN1300133C (zh) | （3r，5r）－3－羟基－5－氨乙基环戊内酯的合成方法 | |
| CN1113894C (zh) | 制备脑啡呔酶与血管紧张素转化酶抑制剂中间体的新方法及其中间体 | |
| CN112939848B (zh) | 一种布比卡因及其中间体(s)-2-哌啶甲酸的制备方法 | |
| CN105017251B (zh) | 一种nk-1受体拮抗剂的制备方法及其中间体 | |
| CN1723188A (zh) | 还原脱卤方法 | |
| CN101654426A (zh) | 制备伊洛马司他的方法 | |
| CN101935302A (zh) | 一种(-)-石杉碱类关键中间体的不对称合成方法 | |
| CN1047387C (zh) | 一种半抗原化合物、合成方法及其用途 | |
| JP3828197B2 (ja) | 光学活性３−（ｐ−メトキシフェニル）グリシッド酸アルカリ金属塩の製造法 | |
| JPH08301825A (ja) | ３’−置換−（２−カルボキシシクロプロピル）グリシン | |
| Figueira et al. | Synthesis of (1R, 3R)-3-[2-(Aminoethyl)-2, 2-dimethylcyclobutyl] methanol and (1S, 3R)-(3-Amino-2, 2-dimethylcyclobutyl) methanol from (+)-Nopinone |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 19990113 Termination date: 20121020 |