CN104147462A - Medicine for treating psoriasis vulgaris - Google Patents

Abstract

The invention relates to a medicine for treating psoriasis vulgaris. The medicine is prepared from the following traditional Chinese herbs in a certain parts by weight: 25-40 parts of radix astragali, 8-15 parts of rhizoma atractylodis, 7-12 parts of dried tangerine or orange peel, 5-15 parts of rhizoma cimicifugae, 12-18 parts of angelica sinensis, 10-15 parts of radix bupleuri, 8-20 parts of root of hairy asiabell, 25-35 parts of rhizoma smilacis glabrae, 6-15 parts of the root bark of the peony tree, and 8-15 parts of honey-fired licorice root. All the raw medicinal materials are added with water to submerge the medicine to be decocted for 1.5 h each time and two times in total; the decocted liquid is filtered, the filtrates for the two times are combined to obtain the decoction in the invention. The medicine disclosed by the invention is mild in property, low in irritation, relatively low in possibility of causing skin damage of new hairs, good in curative effect, free of side effect, and low in possibility of recurrence.

Description

A kind of medicine for the treatment of psoriasis vulgaris

Technical field

The present invention relates to biological medicine technology field, be specifically related to a kind of medicine for the treatment of psoriasis vulgaris.

Background technology

Psoriasis is a kind of dermatosis the most obstinate and that the most easily recur, is known as not dead cancer, to patient, has brought great body and mind painful, and it is thorny that expert doctor quite feels.For many years primary disease has been carried out to large quantity research, manpower and materials all drop into much, but still have problems not break through.Psoriasis treatment is also the problem that the outer experts and scholars of Present Domestic very pay close attention to.

Western medical treatment medication is at present antitumor drug, immunosuppressant, corticosteroid hormone, antibiotics, vitamin medicaments etc., some drugs good effect, but there is great side effect and clinical cannot popularization with it, the recurrent of primary disease is perplexing expert doctor and patient, particularly patient all the time treatment is being lost the confidence in addition, and there is no at present any medicine that can prevent the recurrence of this disease.

Summary of the invention

For above-mentioned situation, the object of this invention is to provide a kind of medicine for the treatment of psoriasis vulgaris, therapeutic effect is good, has no side effect, and relapse rate is low.

Technical scheme of the present invention is as follows: a kind of medicine for the treatment of psoriasis vulgaris is that the Chinese medicine by following parts by weight is that crude drug prepares:

Radix Astragali 25-40 Rhizoma Atractylodis 8-15 Pericarpium Citri Reticulatae 7-12

Rhizoma Cimicifugae 5-15 Radix Angelicae Sinensis 12-18 Radix Bupleuri 10-15

Radix Codonopsis 8-20 Rhizoma Smilacis Glabrae 25-35 Cortex Moutan 6-15

Radix Glycyrrhizae Preparata 8-15.

Preferably, described medicine is that the Chinese medicine by following parts by weight is that crude drug prepares:

The Radix Astragali 30 Rhizoma Atractylodis 10 Pericarpium Citri Reticulataes 10

Rhizoma Cimicifugae 10 Radix Angelicae Sinensis 15 Radix Bupleuri 12

Radix Codonopsis 12 Rhizoma Smilacis Glabrae 30 Cortex Moutans 10

Radix Glycyrrhizae Preparata 10.

The preparation method of medicine of the present invention is: described crude drug is added to water logging and do not have drug decocting, decoct 2 times, each 1.5h, mixes twice filtrate after filtering and obtain decoction of the present invention.

The instructions of taking of medicine of the present invention is each 200ml, every day 2 times.

Prescription of the present invention cures mainly the prolonged illness deficiency of YIN and causes weakness of the spleen and stomach, transporting mistake department, feel again ailment said due to cold or exposure, the psoriasis of nutrient blood due to becoming estranged, controls with invigorating the spleen and replenishing QI hard masses softening and resolving speckle removing, by dredging the meridian, QI and blood regulating, eliminating toxic substances to remove stasis, thereby improve skin lesion form, make it to recover normal, play eliminating pathogenic factor for supporting vital QI, the effect of cure diseases.The Radix Astragali, Radix Codonopsis, Rhizoma Smilacis Glabrae QI invigorating Gu Wei in side, removing toxic substances speckle removing is monarch; Rhizoma Atractylodis, Pericarpium Citri Reticulatae spleen invigorating, dampness removing, and middle stomach reinforcing, Radix Angelicae Sinensis, Cortex Moutan, the removing heat from blood that nourishes blood is minister; Rhizoma Cimicifugae, Radix Bupleuri depressed liver-energy dispersing and QI regulating are assistant; Radix Glycyrrhizae Preparata and middle spleen reinforcing are for making.Gather altogether air making-up and spleen enlivening, the merit of QI invigorating speckle removing.

Pharmaceutical properties of the present invention is gentle, zest is little, the new skin lesion of irritability not relatively, and good effect, has no side effect, and is difficult for recurrence.

Use clinically the decoction of medicine of the present invention to carry out safety and observation of curative effect to treatment psoriasis vulgaris:

Patient's data

Select psoriasis vulgaris patient diagnosed 78 examples, male 41 examples wherein, female's 37 examples, the course of disease 2 months-8 years.

Diagnostic criteria

1, skin lesion is just the red pimple of the extremely lentil-sized inflammatory of needle point, is often drop shape and distributes, increase rapidly, and surface coverage silvery white multilamellar squama, shape is as Muscovitum.After squama is peeled off, visible thin film phenomenon and sieve shape are hemorrhage, and substrate infiltrates, and can have isomorphic response.Outmoded erythra can be coin shape, plate-like, map shape etc.;

2, be apt to occur in scalp, extremity are stretched side, common with elbow joint face, normal general whole body;

3, the visible fingernail pathological changes of part patient, the lighter is pitting, and severe one deck thickens, and gloss disappears.Or be found in oral cavity, pudendum mucosa.Send out in the visible pencil hair of scalp person;

4, onset is slow, is easy to recurrence.Have obvious seasonality, the heavy summer in general winter is light.

Therapeutic Method

Patient takes the decoction of the embodiment of the present invention 1, and each 200ml, every day 2 times, 30 days is a course for the treatment of.

Curative effect determinate standard

Recovery from illness: skin lesion disappears completely, or disappears more than 95%;

Effective: skin lesion disappears more than 50%;

Effective: the skin lesion less than 50% that disappears;

Invalid: skin lesion does not substantially have to change or skin lesion increases the weight of.

Therapeutic outcome

78 routine patients, 23 examples of fully recovering, cure rate 29.4%; Effective 41 examples, obvious effective rate 52.6%; Effective 9 examples, effective 11.5 rates; Total effective rate 93.7%; Invalid 5 examples, inefficiency 6.4%.

The specific embodiment

Embodiment 1

Get Radix Astragali 30g, Rhizoma Atractylodis 10g, Pericarpium Citri Reticulatae 10g, Rhizoma Cimicifugae 10g, Radix Angelicae Sinensis 15g, Radix Bupleuri 12g, Radix Codonopsis 12g, Rhizoma Smilacis Glabrae 30g, Cortex Moutan 10g, Radix Glycyrrhizae Preparata 10g;

Said medicine is added to water logging and do not have drug decocting, decoct 2 times, each 1.5h, mixes twice filtrate after filtering and obtains decoction of the present invention.

Embodiment 2

Get Radix Astragali 35g, Rhizoma Atractylodis 12g, Pericarpium Citri Reticulatae 8g, Rhizoma Cimicifugae 8g, Radix Angelicae Sinensis 12g, Radix Bupleuri 15g, Radix Codonopsis 18g, Rhizoma Smilacis Glabrae 28g, Cortex Moutan 15g, Radix Glycyrrhizae Preparata 12g;

Said medicine is added to water logging and do not have drug decocting, decoct 2 times, each 1.5h, mixes twice filtrate after filtering and obtains decoction of the present invention.

Concrete case

Case one

Feng * *, 22 years old ictal whole body pimple of main cause of female, squama speckle 1 year, patient is pimple, the squama speckle because finding after catching a cold that hairline place Sorghum vulgare Pers. is large the year before, consciously slightly itches, and is treated, and rear erythra increases and is developed to whole body nail cover size squama speckle.After make a definite diagnosis and be diagnosed as psoriasis, oral " Xiaoyin capsule ", external " Jin Niuer " ointment, effect is aobvious, skin lesion is counter to be increased the weight of.Before February, skin rash increases, increases, and companion very itches.Have a medical check-up: 36.5 ℃ of body temperature, normal face, cardiopulmonary abdomen is without positive sign, skin training checks: the intensive nail cover of whole body, to coin size squama speckle, comes off with the visible layer layer micaceous scales of scratching, and substrate is light red, the medicine 5 months of taking the embodiment of the present invention 1, skin rash disappears and takes off, clinical recovery.

Case 2

The Qin * *, 45 years old ictal whole body pimple of main cause of man, squama speckle 16 years, 16 years causes of patient suffer from cold after whole body there is pink Sorghum vulgare Pers. or larger pimple, squama speckle, consciously slightly itch, after my Out-patient Department oral Chinese medicine treatment, cure.8 years cause spirit is hit whole body and is played nail cover to the large squama speckle of coin.Once be interrupted and take " Xiaoyin capsule ", " methotrexate " and repeatedly show effect.February, cause Spring Festival was eaten after pungent stimulation diet, and skin lesion increases increase gradually, and companion's pruritus is had a medical check-up: body temperature 36.2 degree, and normal face, cardiopulmonary abdominal part is without positive sign.Department of dermatologry checks; Whole body map shape erythema, substrate is light red, and without infiltrating, surperficial squama is piled up, and is dirty Lycoperdon polymorphum Vitt oyster shelly, and skin lesion is dry chaps; Scalp portion skin lesion is dry, considers to be worth doing greyish blackly, and substrate is loosening, and hair is broom shape bunch collection; In the form of a ring, edge covers the thick bits of Lycoperdon polymorphum Vitt to back skin lesion, and companion is dry to chap, and is diagnosed as psoriasis vulgaris.The medicine 8 months of taking the embodiment of the present invention 2, skin lesion disappears, clinical recovery.

Case 3

Recklessly * *, male, 15 years old, student.Main cause whole body squamous papule shows effect 1 year repeatedly, and 1 year cause of patient is slept and worked the squamous papule of finding that bilateral ancon is dispersed in, clear border poor morning, strike off squama red color visible thin film and petechial hemorrhage, part can disappear voluntarily, but outbreak repeatedly, the heavy summer in winter is light, and skin lesion increases gradually, expands.In succession there is similar skin lesion in scalp and extremity, without rotten to the corn, sepage.Once after oral western medicine treatment, take a turn for the better, before February there is again new skin lesion in the two lower limb of patient and the both hands back of the body.Have a medical check-up: 36.4 ℃ of body temperature, normal face.Cardiopulmonary abdomen is without positive sign.Skin training checks: whole body skin pale red, kermesinus coin or larger squama speckle, and the visible silvery white micaceous scales of grabbing comes off, duplex portion xerosis cutis, coarse, two lower limb oyster shelly squama speckles, are diagnosed as psoriasis vulgaris.Take the embodiment of the present invention 2 Drug therapys after June skin rash all disappear, spiritual appetite is good, defecation and sleep are normal, clinical recovery.

Case 4

Yellow * *, women, 26 years old, workman.The ictal whole body of main cause pimple, squama speckle 7 years, patient because finding after psychentonia that pink Sorghum vulgare Pers. or larger pimple, squama speckle appear being dispersed in the whole body, was slightly itched before 7 years, and after a few days, carrying out property of skin lesion increases the weight of, once repeatedly oral Chinese medicine treatment expanded gradually without improvement skin lesion, was fused into coin shape.February, cause flu generalized rass expanded, and had a medical check-up: 38.1 ℃ of body temperature, and normal face, cardiopulmonary abdomen is without positive sign.Skin training checks: the red coin of whole body skin powder or larger squama speckle, and the visible silvery white micaceous scales of grabbing comes off, whole body xerosis cutis, coarse, more so, the visible filbert fish scale-shaped squama of local skin lesion, is diagnosed as psoriasis vulgaris to extremity.The Drug therapy of taking the embodiment of the present invention 1 after April skin rash all disappear, clinical recovery.

Case 5

Fiber crops * *, male, 58 years old, workman.Ictal pair of upper limb pimple of main cause, squama speckle 24 years, 24 years causes of patient are rear after suffering from cold finds that pink Sorghum vulgare Pers. or larger pimple, squama speckle appear in two upper limb, consciously slightly itch, after my Out-patient Department oral Chinese medicine treatment, take a turn for the better, easily recurrence after flu afterwards.Before January, two upper limb pimples increase, and have a medical check-up: 36.5 ℃ of body temperature, and normal face, cardiopulmonary abdomen is without positive sign.Skin training checks: greatly or larger squama macule, the visible silvery white micaceous scales of grabbing comes off the pink egg of two skin of upper extremity layer by layer, and two skin of upper extremity are dried, coarse, is diagnosed as psoriasis vulgaris.Take the Drug therapy of the embodiment of the present invention 1 and expose normal skin in skin lesion center after March, the thicker squama speckle in edge.Following the service is two upper limb deflorescences after March, clinical recovery.

Case 6

25 years old ictal whole body pimple of workman's main cause of Zhang Guoqiang man, squama speckle 7 years, after after 7 years cause flu of patient, find that pink Sorghum vulgare Pers. or larger pimple, squama speckle appear in two upper limb, consciously slightly itch, after my Out-patient Department oral Chinese medicine treatment, take a turn for the better, the large rear easily recurrence of learning pressure afterwards.Once personal Beijing opera gold waited ointment, and effect is not aobvious, and skin lesion is counter to be increased the weight of.Before February, skin rash increases, increases, and companion very itches, and haves a medical check-up: 36.5 ℃ of body temperature, and normal face, cardiopulmonary abdomen is without positive sign.Skin training checks: whole body egg arrives greatly map shape squama speckle, coating oyster shelly squama, and whole body skin lesion is dry coarse.Take the medicine of the embodiment of the present invention 2 after 9 months, whole body skin lesion disappears and takes off, clinical recovery.

Claims (3)

1. treat a medicine for psoriasis vulgaris, it is characterized in that the Chinese medicine by following parts by weight is that crude drug prepares:

Radix Astragali 25-40 Rhizoma Atractylodis 8-15 Pericarpium Citri Reticulatae 7-12

Rhizoma Cimicifugae 5-15 Radix Angelicae Sinensis 12-18 Radix Bupleuri 10-15

Radix Codonopsis 8-20 Rhizoma Smilacis Glabrae 25-35 Cortex Moutan 6-15

Radix Glycyrrhizae Preparata 8-15.

2. the medicine for the treatment of psoriasis vulgaris according to claim 1, it is characterized in that the Chinese medicine by following parts by weight is that crude drug prepares:

The Radix Astragali 30 Rhizoma Atractylodis 10 Pericarpium Citri Reticulataes 10

Rhizoma Cimicifugae 10 Radix Angelicae Sinensis 15 Radix Bupleuri 12

Radix Codonopsis 12 Rhizoma Smilacis Glabrae 30 Cortex Moutans 10

Radix Glycyrrhizae Preparata 10.

3. the preparation method of the treatment psoriasis vulgaris medicine described in claim 1 or 2 is: described crude drug is added to water logging and do not have drug decocting, decoct 2 times, each 1.5h, mixes twice filtrate after filtering and obtain decoction of the present invention.