CN104147385B - A kind of formula of Chinese medicine for lowering blood pressure preparation and preparation method - Google Patents
A kind of formula of Chinese medicine for lowering blood pressure preparation and preparation method Download PDFInfo
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- CN104147385B CN104147385B CN201410378417.1A CN201410378417A CN104147385B CN 104147385 B CN104147385 B CN 104147385B CN 201410378417 A CN201410378417 A CN 201410378417A CN 104147385 B CN104147385 B CN 104147385B
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Abstract
The invention discloses a kind of formula and preparation method of Chinese medicine for lowering blood pressure preparation, invention formulation is by pure water, Radix Puerariae, Flos Chrysanthemi Indici, Herba Taxilli, the Cortex Eucommiae, Fructus Crataegi, Radix Scutellariae, Herba Epimedii, Folium et Ramulus Clerodendri Trichotomi, Folium Apocyni Veneti, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Radix Bupleuri, Flos Inulae, Scolopendra, brown sugar and 65% alcoholic solution are through pulverizing, decoct, mixing, the compositions liquid formulation that the techniques such as stirring are prepared into, the preparation that the present invention makes, heat clearing away suppressing the hyperactive liver can be reached, reduce phlegm and invigorate blood circulation, reduce blood pressure and treat the symptoms such as head that excessive rising of liver-YANG causes is dizzy, the present invention can reach antihypertensive effect faster, and it is nontoxic, have no side effect, blood pressure lowering is steady, effect stability, reparation technology is simple and easy to do.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation of hypotensive activity, relate to formula and the preparation method of the Chinese medicine preparation of this hypotensive activity specifically.
Background technology
As a kind of disease that the person is common, cardiovascular disease has become one of big factors threatening mankind nowadays health.In recent years, along with the aging of China's population and the raising of people's living standard, the quickening of life, work rhythm, dietary habit is to the development in high transconversion into heat, high esterified direction, and the hyperpietic in crowd is year after year in increasing trend.
At present, for blood pressure lowering problem, domestic hospitals is commonly used antihypertensive drug and is mainly suppressed (husky smooth class) three major types medicine based on calcium channel blocker (Horizon class), ACE-I (pril) and hypertensinase-II, Western medicine class hypolipidemic is that Statins takes product as the leading factor, and Chinese medicine class cardiovascular disease therapies preparation became the best selling variety on domestic market gradually in the last few years.Compared with Western medicine preparation, the feature that Chinese medicine preparation has " Mutiple Targets, manifold effect ", because theory of Chinese medical science is thought, human body is an entirety, therefore stasis of blood apoplexy due to endogenous wind medical instrument of invigorating blood circulation eliminates atheromatous plaque, dredging vascellum and accelerate the multi-effect such as blood circulation, therefore have more advantage compared with the traditional Chinese medical science class cardiovascular diseases preparation Western medicine preparation single with effect.This shows the accreditation of the numerous patients of China to Chinese medicine class cardiovascular preparation clinical effectiveness, but Chinese medicine is in the market treated some and is cured the symptoms, not the disease, some uses expensive composition, a lot of product antihypertensive effect is not obvious, after blood pressure lowering, effect is unstable, be easy to bounce-back rise, described defective value must improve.
Summary of the invention
Namely object of the present invention is for above-mentioned deficiency, on the basis of secret prescription handed down in the family from generation to generation, in conjunction with modern Chinese and western medicine technology, there is provided a kind of prevention and therapy hypertensive Chinese medicine preparation, be to provide formula and the preparation method of this Chinese medicine preparation specifically, the invention belongs to a kind of heat clearing away suppressing the hyperactive liver, reduce phlegm and invigorate blood circulation, cure mainly the traditional Chinese compound medicine of the symptoms such as head that hypertension and excessive rising of liver-YANG cause is dizzy, the present invention can reach antihypertensive effect faster, and nontoxic, have no side effect, blood pressure lowering is steady, and effect stability, reparation technology is simple and easy to do.
Technical scheme of the present invention is as described below:
Invention formulation is the compositions liquid formulation be prepared into by pure water, Radix Puerariae, Flos Chrysanthemi Indici, Herba Taxilli, the Cortex Eucommiae, Fructus Crataegi, Radix Scutellariae, Herba Epimedii, Folium et Ramulus Clerodendri Trichotomi, Folium Apocyni Veneti, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Radix Bupleuri, Flos Inulae, Scolopendra, brown sugar and 65% alcoholic solution, and wherein the quality proportioning of each component is:
In order to obtain better effect, the present invention can raw material mass mixture ratio be preferably:
Certainly, in order to obtain effect good further, the present invention can raw material mass mixture ratio be preferably also:
The preparation method of above-mentioned Chinese medicine for lowering blood pressure preparation, comprises the steps:
1), by Radix Puerariae, Flos Chrysanthemi Indici, Herba Taxilli, the Cortex Eucommiae, Fructus Crataegi, Radix Scutellariae, Herba Epimedii, Folium et Ramulus Clerodendri Trichotomi prepare in proportion, pulverize and cross 80 mesh sieves, then dry under the high temperature of 50-70 DEG C through pulverizer, room temperature of then naturally drying in the air is for subsequent use;
2), the mixture of powders of Radix Puerariae, Flos Chrysanthemi Indici, Herba Taxilli, the Cortex Eucommiae, Fructus Crataegi, Radix Scutellariae, Herba Epimedii, Folium et Ramulus Clerodendri Trichotomi in above-mentioned steps is added pure water and decoct three times, first time added for 10 times amount soak by water half an hours, second time adds 5 times amount soak by water 20 minutes, third time adds 5 times amount soak by water 10 minutes, then collecting decoction filtering, for subsequent use;
3), by Folium Apocyni Veneti, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Radix Bupleuri, Flos Inulae, Scolopendra prepare in proportion, pulverize and cross 80 mesh sieves, then dry under the high temperature of 50-70 DEG C through pulverizer, room temperature of then naturally drying in the air is for subsequent use;
4) pure water, by the mixture of powders of above-mentioned Folium Apocyni Veneti, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Radix Bupleuri, Flos Inulae, Scolopendra adding 10 times amount decocts half an hour, then gets decocting liquid and filters, for subsequent use;
5), under room temperature state, by above-mentioned steps 2) and step 4) the middle decocting liquid mixing obtained, and add 65% alcoholic solution and stir, form Chinese medicine composition pharmaceutical solutions;
6), by above-mentioned steps 5) in Chinese medicine composition pharmaceutical solutions add brown sugar, and stir 5 minutes, can obtain.
The above-mentioned Chinese medicine composition pharmaceutical solutions produced may be used for oral, if can respectively drink the morning, noon and afternoon once and long-term drink, and better effects if.
Theoretical foundation of the present invention is:
Radix Puerariae is legume pueraria lobata, be that the one of some provinces and regions of southern china often eats vegetable, its sweet in the mouth is cool good to eat, is often used as Baoshang.Its main component is starch, in addition containing have an appointment 12% flavone compound, comprise Semen sojae atricolor (Semen Glycines) glycoside, daidzein, puerarin etc. more than 10 and plant; And containing daucosterol, aminoacid, Coumarins etc.As Chinese medicine, Radix Puerariae is cool in nature, sweet in the mouth, pungent, and be conventional expelling pathogenic wind from the body surface medicine, clinical report is used for the treatment of hypertension and shows with neck pain person's curative effect.Update shows, Radix Puerariae has α receptor and angiotensin-ii-receptor also has blocking effect, and curative effect is better than all kinds of antihypertensive drug in the past.Especially the myocardial hypertrophy of possibility caused by reversing hypertension.Puerarin can make endothelin level (ET) level obviously increased comparatively fast recover normal, therefore one of mechanism of Treatment of Hypertension with Puerarine may be to suppress the excessive release of ET, promote endothelium restore funcitons, and then excited PG12 synthase activity, significantly increase EC and generate PG anticoagulant, play and improve sanguimotor effect.Heavy dose of puerarin can reduce blood glucose, obviously can reduce serum cholesterol.But alone Radix Puerariae carrys out blood pressure lowering, result is also not obvious, but carrys out Hypertension with other drug matchings in the present invention, and blood pressure lowering result is obvious, has good effect to the symptom such as headache, dizziness, limb fiber crops, tinnitus that hypertension causes.
Flos Chrysanthemi Indici, be the head inflorescence of Compositae herbaceos perennial Herba Dendranthematis indici, profile is similar to Flos Chrysanthemi, wild by patana, field wing.Flos Chrysanthemi Indici can be widely used in heat-clearing and toxic substances removing, treatment furuncle carbuncle, laryngopharynx swelling and pain, wind-fire acute conjunctivitis, the disease such as dizzy of having a headache.There is again good hypotensive effect simultaneously, can be used for the auxiliary treatment of hypertension.Single decoction effect is general, but associates with other Chinese medicines of the present invention, then effect is very outstanding.
Herba Taxilli, bitter in the mouth; Sweet; Property flat, enter liver, kidney channel, can wind-damp dispelling, invigorating the liver and kidney, nourishing blood and preventing abortion, the muscles and bones be mainly used in caused by arthromyodynia blood failing to nourish tendons, deficiency of the liver and kindey is withered the diseases such as weak, soreness of the waist and knees, is also usually used in the treatment of hypertension of deficiency of yin of liver and kidney type disease.
The Cortex Eucommiae is the dry bark of the Eucommiaceae plant Cortex Eucommiae, is Chinese famous and precious tonic herb.Take Folium Eucommiae as the Cortex Eucommiae tea set invigorating the liver and kidney of raw material, bone and muscle strengthening, blood pressure lowering, many effects such as antiabortive.The Cortex Eucommiae is sweet in flavor and warm in property, has invigorating the liver and kidney, bone and muscle strengthening, antiabortive blood pressure lowering effectiveness, can blood pressure lowering with the compatibility such as Herba Taxilli, Pheretima, and to people's blood pressure lowering of body void without cold and cool fraud.
Fructus Crataegi is edible plants, stone fruit, and matter is hard, and sarcocarp is thin, and taste is micro-sour and astringent.Thornbuss is machaka.The close life of branch, have spinelet, sprout has pubescence.Sprig puce, old branch taupe.Fructus Crataegi is China distinctive medicine fruit dual-purpose seeds.Fructus Crataegi can removing food stagnancy, clots absorbing, changes stagnant, the sweet slightly warm in nature of Fructus Crataegi sour in the mouth, Fructus Crataegi energy prevention and cure of cardiovascular disease, has blood vessel dilating, heart tonifying, increase coronary flow, improves heart vigor, stimulating central nervous system system, reduces blood pressure and cholesterol, vessel softening and diuresis and sedation; Prevent and treat arteriosclerosis, anti-aging, anticancer effect.Crataegolic acid also has cardiotonic, also benefits to senile heart disease.
Radix Scutellariae, can heat clearing away solution wet, eliminating fire and detoxication, and its bitter in the mouth is trembled with fear, effectiveness promoting digestion and removing stagnation, blood pressure lowering of invigorating blood circulation, and heat clearing away solution wets, and eliminating fire and detoxication, tackles the hypertension of Liver Channel excess-heat, has and removes dizzy, headache, bitter taste, vexed effectiveness.No matter be decoct, preserved material, all have obvious blood pressure lowering effectiveness, to treat nerve hypertension and treating arteriosclerosis hypertension sick with the compatibility such as Flos Chrysanthemi Indici, Ramulus Uncariae Cum Uncis, and blood pressure can be made low, and headache, the symptom such as uncomfortable in chest, impetuous obviously improve and disappear.
Herba Epimedii, another name ferrum arrow, Birdfoot, be long greenweed wood, be born in dark and damp gully, woods is mixed on hillside or in bamboo clump, warm in nature, acrid-sweet flavor, kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; The symptoms such as climacteric hypertension.
Folium et Ramulus Clerodendri Trichotomi has another name called clerodendron trichotomum, the red five-pointed star in Mount Taishan, flower bulb paulownia, anistree Firmiana platanifolia (Linn. f.) Marsili, Flos Echinopsis latifolii, backyard flower etc., and property is pungent, bitter in the mouth, sweet, cool, enters Liver Channel, gallbladder meridian, spleen channel.Rheumatic arthralgia can be treated, hemiplegia, hypertension, migraine; Malaria, dysentery, hemorrhoid, carbuncle skin ulcer scabies.Folium et Ramulus Clerodendri Trichotomi is after high heat decocts, and hypotensive effect weakens.But with other drug matchings in the present invention, then drug effect is unaffected.
Folium Apocyni Veneti, be the leaf of Herba Apocyni veneti, many shrinkages are curling, and some fragmentations can treat hypertension, and Folium Apocyni Veneti decoct has hypotensive effect; Root of Apocynum venetum L. decoct has cardiotonic; Folium Apocyni Veneti extractum has calmness, anticonvulsant action, and has stronger diuresis, reduction blood fat, immunity moderation, defying age and suppress the effects such as influenza virus.
Pheretima, cold in nature, salty in the mouth.Can heat clearing away arresting convulsion, dredging collateral, to relieving asthma, diuresis; Twitch for unconsciousness due to high fever infantile convulsion, joint is benumbed, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, vascular hypertension.
Rhizoma Gastrodiae is herbaceos perennial, is distributed in national most area.Its dry tuber, also known as Rhizoma Gastrodiae, is commonly use and famousr and precious Chinese medicine simply, is clinically used for the disease such as headache dizzy, numb limbs and tense tendons, infantile convulsion, epilepsy, tic, tetanus, can stop working by suppressing the hyperactive liver, is applicable to the headache caused by excessive rising of liver-YANG, the disease such as dizzy.
Ramulus Uncariae Cum Uncis, another name is again large Ramulus Uncariae Cum Uncis, Ramulus Uncariae macrophyllae, for Maguireothamnus speciosus Ramulus Uncariae Cum Uncis or Uncaria sinensis (Oliv.) Havil. and the buckle branch belonging to various plants together thereof, climb up by holding on to shape shrub, Ramulus Uncariae Cum Uncis sweet in the mouth, cold nature, can to stop working heat clearing away by suppressing the hyperactive liver, the diseases such as available, conjunctival congestion logical with dizzy, the head caused by excessive rising of liver-YANG, containing multiple indoles alkaloid in Ramulus Uncariae Cum Uncis stem branch, comprise Ramulus Uncariae cum Uncis alkali, isorhynchophylline, Rhomotoxine, and non-alkaloid.In Ramulus Uncariae Cum Uncis, main effectively antihypertensive compositions is Ramulus Uncariae cum Uncis alkali and isorhynchophylline, and the antihypertensive effect of the latter is better than Ramulus Uncariae cum Uncis alkali.
Rhizoma Chuanxiong, a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, Main Cultivation in Sichuan, Yunnan, Guizhou, Guangxi, the ground such as Hubei.The pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, and the up mountain peak that reaches is pushed up; Enter blood system again, descendingly reach the sea of blood.Blood circulation promoting and blood stasis dispelling effect is extensive, the suitable various disease of stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is gas medicine in blood that former times people calls Rhizoma Chuanxiong, the functions such as pungent loose, the resolving depression of its residence of dangerous speech, sensible, pain relieving.
Radix Bupleuri, meridian distribution of property and flavor: cold nature, bitter in the mouth, pungent, return Liver Channel, gallbladder meridian, tool depressed liver-energy dispersing and function of gallbladder promoting, dredge gas resolving depression, loose effect of fire.
Flos Inulae, has another name called donkey grass, Flos Inulae.Perennial herb, stem tool indulges rib, green or micro-band aubergine.Leaf alternate, ellipse, ellipticity lanceolar or long narrow ellipse.Head inflorescence minority or majority, top is raw, and arrange in umbrella room shape, Flos Inulae is salty, warm, slightly poisonous, for expectorant, the therapeutic method to keep the adverse QI flowing downwards, softening the hard mass, row water.
Scolopendra is Lu Sheng arthropod, and health is made up of many body segments, and on each joint, all length has step, therefore is that polypody is biological.Their action are rapidly, aggressive.In the traditional Chinese medical science, Scolopendra returns Liver Channel, can endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom etc.
65% alcoholic solution spirituosity, the title that Chinese liquor have " length of hundred medicines ", Chinese liquor stable in properties, safe and effective, and because ethanol is a kind of good semi-polarity organic solvent, the various effective ingredient of Chinese medicine are all soluble in wherein, wine assisting drug, wine help medicine gesture and give full play to its effect, improve therapeutic effect.
As everyone knows, hypertension refers to regulating blood pressure obstacle, and systemic arterial blood pressure continues the pathological process raised.Hypertensive diagnostic criteria refers to that systolic arterial pressure and/or diastolic pressure increase (>=140/90mmHg) under quiescent condition, normal with organ functional or organic changes such as fat and sugar metabolism disorder and the heart, brain, kidney and retinas, reinvent the systemic disease into feature with organ.Have a rest more than 5 minutes, more than 2 times the non-blood pressure >=140/90mmHg recorded on the same day can be diagnosed as hypertension.Clinically a lot of hypertensive patient particularly obese type is often with diabetes, and diabetes are also more with hypertension, therefore both are referred to as homology disease.Diabetes patient increases due to blood glucose, and blood viscosity increases, and blood vessel wall is impaired, and vascular resistance increases, and easily causes hypertension.It can thus be appreciated that hypertension and diabetes are all relevant with hyperlipidemia, therefore preventing and treating hypertension and diabetes all should blood pressure lowering, adjusting blood lipid simultaneously.
China's traditional Chinese medical science is thought, hypertension is because of feelings will internal injury, eating and drinking without temperance, overstrain damage, or asthenia with age, and deficiency of the kidney etc. cause internal organs imbalance between YIN and YANG, raw in wind-fire, and expectorant becomes silted up and hands over resistance, QI and blood inverse disorderly caused by.Usually following several types is divided into: liver-Yang sthenia type, liver-kidney yin deficiency, deficiency of both YIN and YANG type, stagnation of turbid phlegm in middle-JIAO type, congestion accumulation type, Chong and Ren channel disorder type etc. are several during treatment.
Western medicine also treats hypertension, and doctor trained in Western medicine is usually promising to be reached target blood pressure and frequently adds and subtracts the situations such as dose, therefore, also usually occurs the phenomenon that fluctuation of blood pressure amplitude is larger.And Chinese medicine for lowering high blood pressure effect relaxes, stabilizing blood pressure effect is better, and the present invention is particularly useful in early days, middle and old age hypertension patient, and heavier hypertension coordinates treatment by Chinese herbs of the present invention, also can prevent blood pressure larger fluctuation.
When technical solution of the present invention does not disclose, within the time of 15 month of in March, 2013 in May, 2014, select the associated hypertension case of each large and small type institute of traditional Chinese medicine of Shenzhen, follow-up investigation.Now itemize several typical case.
(1) Yang, man, 54 years old, snack bar storekeeper.Before this patient consumes ill 8 years, body weight 85 kilograms, dizzy, high pressure 163, low pressure 102.On April 14th, 2013 seeks medical advice and starts to take Chinese medicine preparation of the present invention, takes at 1 hour after the meal, every day 3 times, each 300ml, and 1 month was 1 course for the treatment of, and detect blood pressure after taking three courses for the treatment of, high pressure 145, low pressure 90, dizziness alleviates, and has no side effect.For firm effect, continue to take medicine.
(2) beam so-and-so, man, 66 years old, retired cadre.This patient detected to suffer from hypertension in 2010, its high pressure 155, low pressure 98, and seeking medical advice on June 3rd, 2013 starts to take this Chinese medicine preparation,, took at 1 hour after the meal, every day 3 times, each 300ml, 1 month was 1 course for the treatment of, and detect high pressure 133 after taking four courses for the treatment of, low pressure 85, has no side effect.
(3) Zhang, female, 46 years old, bank clerk.High pressure 146 before this patient consumes, low pressure 95, starts to take Chinese medicine preparation of the present invention in JIUYUE, 2013, takes at 1 hour after the meal, every day 3 times, each 300ml, and 1 month was 1 course for the treatment of, and detect blood pressure after taking two courses for the treatment of, high pressure 128, low pressure 84, without malaise symptoms.
(4) Zhang, man, 69 years old, unemployed.This patient suffers from hypertension 14 years, seeks medical advice for many years and takes antihypertensive drugs, but be not improved, high pressure 173, low pressure 105, and with dizziness, limply symptom.Start to take Chinese medicine preparation of the present invention on June 28th, 2013, took at 1 hour after the meal, every day 3 times, each 300ml, it within 1 month, was 1 course for the treatment of, blood pressure is detected, high pressure 146, low pressure 93 after taking six courses for the treatment of, dizziness alleviates, myasthenia of limbs symptom improves, and without malaise symptoms, rear continuation takes.
(5) Lee so-and-so, female, 48 years old, certain company manager.High pressure 144 before taking medicine, low pressure 93.On February 21st, 2014 starts to take this Chinese medicine preparation, takes at 1 hour after the meal, every day 3 times, each 300ml, and 1 month was 1 course for the treatment of, and after taking three courses for the treatment of, high pressure 128, low pressure 83, without bounce-back sign after drug withdrawal.
(6) Lee so-and-so, man, 45 years old, company clerk.High pressure 141 before taking medicine, low pressure 96, continues 1 year, with the symptom of slight giddy, feeling of fullness in the head, start to take this Chinese medicine preparation with on March 4th, 2014, took at 1 hour after the meal, every day 3 times, each 300ml, 1 month was 1 course for the treatment of, and after taking two courses for the treatment of, blood pressure drops to normal level, the temporary nothing of symptom of giddy, feeling of fullness in the head, has no side effect.
In conjunction with above clinical data and theoretical foundation of the present invention, visible beneficial effect of the present invention is, the preparation that the present invention makes, and can reach heat clearing away suppressing the hyperactive liver, reduce phlegm and invigorate blood circulation, reduce blood pressure and treat the symptoms such as head that excessive rising of liver-YANG causes is dizzy, the present invention can reach antihypertensive effect faster, and nontoxic, have no side effect, blood pressure lowering is steady, and effect stability, reparation technology is simple and easy to do.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is explained detailedly:
embodiment 1:
Invention formulation is the compositions liquid formulation be prepared into by pure water, Radix Puerariae, Flos Chrysanthemi Indici, Herba Taxilli, the Cortex Eucommiae, Fructus Crataegi, Radix Scutellariae, Herba Epimedii, Folium et Ramulus Clerodendri Trichotomi, Folium Apocyni Veneti, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Radix Bupleuri, Flos Inulae, Scolopendra, brown sugar and 65% alcoholic solution, and wherein the quality proportioning of each component is:
The preparation method of above-mentioned Chinese medicine for lowering blood pressure preparation, comprises the steps:
1), by Radix Puerariae, Flos Chrysanthemi Indici, Herba Taxilli, the Cortex Eucommiae, Fructus Crataegi, Radix Scutellariae, Herba Epimedii, Folium et Ramulus Clerodendri Trichotomi prepare in proportion, pulverize and cross 80 mesh sieves, then dry under the high temperature of 50-70 DEG C through pulverizer, room temperature of then naturally drying in the air is for subsequent use;
2), the mixture of powders of Radix Puerariae, Flos Chrysanthemi Indici, Herba Taxilli, the Cortex Eucommiae, Fructus Crataegi, Radix Scutellariae, Herba Epimedii, Folium et Ramulus Clerodendri Trichotomi in above-mentioned steps is added pure water and decoct three times, first time added for 10 times amount soak by water half an hours, second time adds 5 times amount soak by water 20 minutes, third time adds 5 times amount soak by water 10 minutes, then collecting decoction filtering, for subsequent use;
3), by Folium Apocyni Veneti, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Radix Bupleuri, Flos Inulae, Scolopendra prepare in proportion, pulverize and cross 80 mesh sieves, then dry under the high temperature of 50-70 DEG C through pulverizer, room temperature of then naturally drying in the air is for subsequent use;
4) pure water, by the mixture of powders of above-mentioned Folium Apocyni Veneti, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Radix Bupleuri, Flos Inulae, Scolopendra adding 10 times amount decocts half an hour, then gets decocting liquid and filters, for subsequent use;
5), under room temperature state, by above-mentioned steps 2) and step 4) the middle decocting liquid mixing obtained, and add 65% alcoholic solution and stir, form Chinese medicine composition pharmaceutical solutions;
6), by above-mentioned steps 5) in Chinese medicine composition pharmaceutical solutions add brown sugar, and stir 5 minutes, can obtain.
The above-mentioned Chinese medicine composition pharmaceutical solutions produced may be used for oral, if can respectively drink the morning, noon and afternoon once and long-term drink, and better effects if.
embodiment 2:
The present invention can raw materials quality be preferably also (gram):
Preparation method is as embodiment 1.
embodiment 3:
Wherein the quality of each component is (gram):
Preparation method is as embodiment 1.
embodiment 4:
Wherein the quality of each component is (gram):
Preparation method is as embodiment 1.
embodiment 5:
Wherein the quality of each component is (gram):
Preparation method is as embodiment 1.
embodiment 6:
Wherein the quality of each component is (gram):
Preparation method is as embodiment 1.
Above-described embodiment is only the several of the numerous embodiment of the present invention, and as strengthened in the ratio in technical scheme by each formula or reducing dose, obtained this blood pressure lowering preparation curative effect is also unaffected, also will drop within the scope of the present invention.
Claims (4)
1. a Chinese medicine for lowering blood pressure preparation, it is characterized in that, this preparation is the compositions liquid formulation be prepared into by pure water, Radix Puerariae, Flos Chrysanthemi Indici, Herba Taxilli, the Cortex Eucommiae, Fructus Crataegi, Radix Scutellariae, Herba Epimedii, Folium et Ramulus Clerodendri Trichotomi, Folium Apocyni Veneti, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Radix Bupleuri, Flos Inulae, Scolopendra, brown sugar and 65% alcoholic solution, and wherein the quality of each component is:
2. Chinese medicine for lowering blood pressure preparation according to claim 1, is further characterized in that, wherein the quality of each component is:
3. Chinese medicine for lowering blood pressure preparation according to claim 1 and 2, is further characterized in that, wherein the quality of each component is:
4. the preparation method of a kind of Chinese medicine for lowering blood pressure preparation according to claim 1, it is characterized in that, it comprises the steps:
1), by Radix Puerariae, Flos Chrysanthemi Indici, Herba Taxilli, the Cortex Eucommiae, Fructus Crataegi, Radix Scutellariae, Herba Epimedii, Folium et Ramulus Clerodendri Trichotomi prepare by described consumption, pulverize and cross 80 mesh sieves, then dry under the high temperature of 50-70 DEG C through pulverizer, room temperature of then naturally drying in the air is for subsequent use;
2), the mixture of powders of Radix Puerariae, Flos Chrysanthemi Indici, Herba Taxilli, the Cortex Eucommiae, Fructus Crataegi, Radix Scutellariae, Herba Epimedii, Folium et Ramulus Clerodendri Trichotomi in above-mentioned steps is added pure water and decoct three times, first time added for 10 times amount soak by water half an hours, second time adds 5 times amount soak by water 20 minutes, third time adds 5 times amount soak by water 10 minutes, then collecting decoction filtering, for subsequent use;
3), by Folium Apocyni Veneti, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Radix Bupleuri, Flos Inulae, Scolopendra prepare by described consumption, pulverize and cross 80 mesh sieves, then dry under the high temperature of 50-70 DEG C through pulverizer, room temperature of then naturally drying in the air is for subsequent use;
4) pure water, by the mixture of powders of above-mentioned Folium Apocyni Veneti, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Radix Bupleuri, Flos Inulae, Scolopendra adding 10 times amount decocts half an hour, then gets decocting liquid and filters, for subsequent use;
5), under room temperature state, by above-mentioned steps 2) and step 4) the middle decocting liquid mixing obtained, and add 65% alcoholic solution and stir, form Chinese medicine composition pharmaceutical solutions;
6), by above-mentioned steps 5) in Chinese medicine composition pharmaceutical solutions add brown sugar, and stir 5 minutes, can obtain, the above-mentioned Chinese medicine composition pharmaceutical solutions produced is for oral.
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| CN2013103439266A CN103393958A (en) | 2013-08-09 | 2013-08-09 | Formula and preparing method of blood pressure-reducing traditional Chinese medicine preparation |
| CN201410378417.1A CN104147385B (en) | 2013-08-09 | 2014-08-04 | A kind of formula of Chinese medicine for lowering blood pressure preparation and preparation method |
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| CN103656303A (en) * | 2013-12-17 | 2014-03-26 | 青岛中科菲力工程技术研发有限公司 | Traditional Chinese medicine capsule with function of reducing blood pressure and preparation method of traditional Chinese medicine capsule |
| CN103751334B (en) * | 2014-01-02 | 2016-03-09 | 王静业 | One treats hypertensive medicine and preparation method thereof |
| CN104524240A (en) * | 2014-11-28 | 2015-04-22 | 潘景山 | Traditional Chinese medicinal formula for treating hypertension |
| CN104606566A (en) * | 2015-02-28 | 2015-05-13 | 陈彬 | Traditional Chinese medicine composition for treating liver-yang hyperactivity hypertension and preparation method for traditional Chinese medicine composition |
| CN104840776A (en) * | 2015-06-03 | 2015-08-19 | 广西大学 | Traditional Chinese medicine for reducing blood pressure |
| CN110680881A (en) * | 2019-10-24 | 2020-01-14 | 苏州焦安娜医药科技有限公司 | Traditional Chinese medicine for reducing blood pressure and preparation method thereof |
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| CN1352983A (en) * | 2001-11-23 | 2002-06-12 | 郑国芃 | Chinese medicine for treating hypertension |
| CN102293947A (en) * | 2011-09-28 | 2011-12-28 | 曹文真 | Traditional Chinese medicine for treating hypertension |
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| CN102423421B (en) * | 2011-12-06 | 2014-06-11 | 陈中元 | Medicine for treating hypertension |
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| CN101129817B (en) * | 2007-09-26 | 2010-06-30 | 王伏春 | Chinese medicine formulation for treating hypertension and method of producing the same |
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- 2013-08-09 CN CN2013103439266A patent/CN103393958A/en active Pending
- 2013-10-12 WO PCT/CN2013/085146 patent/WO2015018129A1/en active Application Filing
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| CN1352983A (en) * | 2001-11-23 | 2002-06-12 | 郑国芃 | Chinese medicine for treating hypertension |
| CN102258693B (en) * | 2010-05-25 | 2012-10-17 | 湖北神农本草中药饮片有限公司 | Traditional Chinese medicine for treating hypertension |
| CN102293947A (en) * | 2011-09-28 | 2011-12-28 | 曹文真 | Traditional Chinese medicine for treating hypertension |
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| WO2015018129A1 (en) | 2015-02-12 |
| CN103393958A (en) | 2013-11-20 |
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