CN104147274B - Treat the psoriasic Chinese medicine composition of stagnated heat of liver channel type - Google Patents

Treat the psoriasic Chinese medicine composition of stagnated heat of liver channel type Download PDF

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CN104147274B
CN104147274B CN201410346836.7A CN201410346836A CN104147274B CN 104147274 B CN104147274 B CN 104147274B CN 201410346836 A CN201410346836 A CN 201410346836A CN 104147274 B CN104147274 B CN 104147274B
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CN104147274A (en
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陈敏斐
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GUANGXI WUZHOU SANHE PHARMACEUTICAL Co.,Ltd.
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Abstract

The present invention relates to one kind to treat the psoriasic Chinese medicine composition of stagnated heat of liver channel type, is related to the field of Chinese medicines, the raw material that it includes following parts by weight is made:13 parts~17 parts of trident quassia, 10 parts~14 parts of mountain breeze, 18 parts~22 parts of ox rattan, 8 parts~12 parts of Siberian cocklebur grass, 18 parts~22 parts of scrawly handwriting, wear 10 parts~14 parts of floricome, 6 parts~10 parts of Common Camptotheca Fruit, 13 parts~17 parts of waterlettuce herb, 10 parts~14 parts of Semi-pinnated Brake Herb, 13 parts~17 parts of 10 parts~14 parts of the fleece-flower root, 4 parts~8 parts of rush and fructus cannabis.The present invention has Shugan Qingre, calms the nerves the effect of antipruritic, and for stagnated heat of liver channel type psoriasis treatment, its is curative for effect, stable dosage forms, quality controllable and have no toxic side effect, and is the Modern preparations for being easy to be applied extensively.

Description

Treat the psoriasic Chinese medicine composition of stagnated heat of liver channel type
Technical field
The present invention relates to the field of Chinese medicines, especially one kind to treat the psoriasic Chinese medicine composition of stagnated heat of liver channel type.
Background technology
Psoriasis also known as psoriasis, it is chronic erythroderma desquamativum that is a kind of common and easily recurring.Psoriasic base This infringement is the silvery white scales of skin that peel off erythema with characteristic, common with four limbs, scalp, the north, and the mostly weight summer in winter is light, psoriasis The all age group from childhood to old age is found in, men and women falls ill without big difference.As traditional Chinese medicine is recognized for the psoriasis interpretation of the cause, onset and process of an illness That knows deepens continuously, and modern age, each middle doctor was substantially classified as 4 types according to its skin lesion feature:That is blood heat wind-dryness type, stagnated heat of liver channel Type, blood-dryness type, blood stasis type.
Wherein, stagnated heat of liver channel type psoriatic dry skin, it is coarse, thicken, the violent itch in affected part, grab after scratching occur tide Red, scab is more, and with dry, vexed, irritability, dry and hard excrement, scanty drak urine, red tongue with yellowish fur, the symptom such as veins string or chord number, in feelings Itch aggravates when thread fluctuates.
Antipsoriatics more commonly used at present has corticoid and antineoplastic etc..
Corticoid:It is broadly divided into external application and takes two kinds orally.What the externally applied drug that treatment ox-hide is permitted was commonly used has PIKANGWANG, pleasure Skin liquid, clobetasol, compound lactic acid emulsifiable paste etc..For oral administration has prednisone, dexamethasone etc..The main work(of such medicine can be mitigated Inflammation and the propagation for cutting down Skin Cell, and restrain the immune reflection of psoriatic.Short-term appropriate use can improve skin Rash, it also external application or may only can just be used under the suggestion of doctor during use, avoid persistently using.Otherwise local skin is easily made Atrophy, the state of an illness is set more to deteriorate.
Antineoplastic:The psoriasic medicine of major control has bis-morpholine, amethopterin, aminopterin, ethyleneimine etc..It is such Medicine is to make helping to change for the obvious reduction of psoriasis fash or regression by restraining cell and isolating to reach, but to organism normal cell Development isolate and crush very big, the immune work(for seriously having crushed human normal can be with, and malicious pair can also occur and help to change, and dosage Bigger, malicious pair is helped to change also bigger.So when suggesting patient using antineoplastic treatment psoriasis, use must be correctly held The dosage and the course for the treatment of of medicine, and further consultation on time.
The content of the invention
It is an object of the invention to provide one kind to treat the psoriasic Chinese medicine composition of stagnated heat of liver channel type, the Chinese medicine composition There is the effect of good on treating stagnated heat of liver channel type psoriasis.
In order to solve the above-mentioned technical problem, the technical solution adopted in the present invention is:
It includes the raw material of following parts by weight:
13 parts~17 parts of trident quassia, 10 parts~14 parts of mountain breeze, 18 parts~22 parts of ox rattan, 8 parts~12 parts of Siberian cocklebur grass, ghost 18 parts~22 parts of Taoism draw magic figures or incantations, wears 10 parts~14 parts of floricome, 6 parts~10 parts of Common Camptotheca Fruit, 13 parts~17 parts of waterlettuce herb, and 10 parts of Semi-pinnated Brake Herb~ 14 parts, 10 parts~14 parts of the fleece-flower root, 13 parts~17 parts of 4 parts~8 parts of rush and fructus cannabis.
In above-mentioned technical proposal, more specifically scheme is:The parts by weight of raw material are:15 parts of trident quassia, 12 parts of mountain breeze, 20 parts of ox rattan, 10 parts of Siberian cocklebur grass, 20 parts of scrawly handwriting wear 12 parts of floricome, 8 parts of Common Camptotheca Fruit, 15 parts of waterlettuce herb, 12 parts of Semi-pinnated Brake Herb, 15 parts of 12 parts of the fleece-flower root, 6 parts of rush and fructus cannabis;
Further:The parts by weight of raw material are:13 parts of trident quassia, 14 parts of mountain breeze, 22 parts of ox rattan, 8 parts of Siberian cocklebur grass, 18 parts of scrawly handwriting, wears 14 parts of floricome, 6 parts of Common Camptotheca Fruit, 17 parts of waterlettuce herb, 14 parts of Semi-pinnated Brake Herb, 10 parts of the fleece-flower root, 4 parts of rush with And 13 parts of fructus cannabis;
Further:The parts by weight of raw material are:17 parts of trident quassia, 10 parts of mountain breeze, 18 parts of ox rattan, Siberian cocklebur grass 12 Part, 22 parts of scrawly handwriting, wear 10 parts of floricome, 10 parts of Common Camptotheca Fruit, 13 parts of waterlettuce herb, 10 parts of Semi-pinnated Brake Herb, 14 parts of the fleece-flower root, rush 8 17 parts of part and fructus cannabis.
Further, mixture, granule or capsule is made in the psoriasic Chinese medicine composition for the treatment of stagnated heat of liver channel type.
Trident quassia in the present invention is the drying stem of rue plant evodia lepta, has clearing heat and detoxicating, dispelling wind and eliminating dampness, is subsided a swelling The effect of analgesic, suitable for diseases such as anemopyretic cold, abscess of throat, arthralgia pain due to rheumatism, stable damage, sore, pruituses.
Mountain breeze in the present invention is the drying herb of feverfew fragrance virtue Blumea balsamifera, and acrid flavour, slight bitter are warm-natured, have wind-dispelling Detumescence, promoting blood circulation are antipruritic.Suitable for diseases such as rheumatic arthralgia, eczema, pruitus, traumatism and bleedings.
Ox rattan in the present invention is sweet, light, cool in nature, has clearing away summerheat, wind-damp dispelling, palpus muscles and bones, suitable for heatstroke, sense Cough is emitted, is vomited and diarrhoea, rheumatic arthritis, hemorrhoid hemorrhage, boil carbuncle swells, traumatic injury, fracture, outside for skin eczema, itch, is twined The diseases such as waist erysipelas.
Siberian cocklebur grass in the present invention has a dispersing wind and cold, clearing the nasal passage, wind-damp dispelling, it is antipruritic the effect of, cure mainly nasosinusitis, chill head Bitterly, the diseases such as arthralgia pain due to rheumatism, rubella, eczema, mange.
Scrawly handwriting in the present invention is the drying complete stool of euphorbia plant Fruticose Breyniae Leaf and Twig, and mildly bitter flavor is puckery, cool in nature, slightly poisonous, tool There is clearing heat and detoxicating, blood stasis removing analgesic, restrain antipruritic.Generated heat suitable for abnormal pigmentary deposit on the skin acute diseases such as cholera and sunstroke, headache, acute gastroenteritis, tonsillitis, postpartum uterine contraction Bitterly, the diseases such as functional uterine bleeding, carbuncle carbuncle swells, paint poison, skin eczema, allergic dermatitis, snakebite.
The dried leaf that floricome is rue tannin plant euchretaleaf jasminorange branchlet and leaf of wearing in the present invention, has and expels pathogenic wind from the body surface, promoting the circulation of qi inducing diaphoresis, Promoting blood circulation to remove blood stasis, suitable for cold, fever, bronchitis, asthma, rheumatic numbness, arthralgia and myalgia, stable blood stasis and swelling pain, stomach and intestine are swollen The diseases such as gas, stomachache, pruitus, eczema.
Common Camptotheca Fruit in the present invention is cold in nature, bitter, puckery, has an anticancer, dissipating bind, the effect of blood-breaking stagnation resolvation.
Waterlettuce herb in the present invention, complete stool can hyoscine, have a refreshing and detoxicating, the work(such as dehumidifying wind-dispelling heat and external application herpes simplex Effect.
Semi-pinnated Brake Herb in the present invention has hemostasis, myogenic, removing toxic substances, detumescence and other effects, is spitted blood suitable for controlling, traumatism and bleeding, The diseases such as carbuncle on the back, furunculosis, stable damage, red eye, swell pain.
The fleece-flower root in the present invention has a tonifying liver, kidney-nourishing, blood-nourishing, the effect of wind-dispelling, cures mainly liver-kidney Yin deficiency, and hair must be early white, The deficiency of blood is dizzy, and waist and knee is weak, and muscles and bones is ached, and passes out semen, collapses band, chronic malaria, protracted dysentery, chronic hepatitis, carbuncle swells, scrofula, intestines wind, haemorrhoids etc. Disease.
Rush in the present invention, its stem marrow or all herbal medicine have the effect of clearing heart fire, clearing damp and promoting diuresis, can control leaching The diseases such as disease, oedema, dysphoria and insomnia, larynx numbness, wound.
Fructus cannabis in the present invention is sweet, mild-natured, have can beneficial spleen qi-restoratives, nourishing yin to moisten dryness, the effect of defaecation, suitable for pin The diseases such as wind-puff pain, physically weak early ageing, insufficiency of heart yin, palpitation and restlessness, deficiency of blood Tianjin wound, dry constipation of intestines.
Due to using above-mentioned technical proposal, the beneficial effect that the present invention obtains is:
The present invention be according to Traditional Chinese Medicine and strong medical knowledge opinion, by scientific compatibility, and grope exploitation through experiment for many years and Obtain;The Chinese medicine composition has Shugan Qingre, calms the nerves the effect of antipruritic, for stagnated heat of liver channel type psoriasis treatment, its Curative for effect, stable dosage forms are quality controllable and have no toxic side effect, and are the Modern preparations for being easy to be applied extensively.
Embodiment
Below in conjunction with specific embodiment, the invention will be further described, and protection scope of the present invention is not only limited to In following examples.
Embodiment 1:Treat the preparation of the psoriasic Chinese medicine composition mixture of stagnated heat of liver channel type
Trident quassia 15g is weighed respectively, mountain breeze 12g, ox rattan 20g, Siberian cocklebur grass 10g, scrawly handwriting 20g, wears floricome 12g, Common Camptotheca Fruit 8g, waterlettuce herb 15g, Semi-pinnated Brake Herb 12g, fleece-flower root 12g, rush 6g, fructus cannabis 15g and sucrose 50g, it is standby;Will The sucrose weighed in advance dissolves by heating, and boils, and stops heating, filters while hot, standby;By the above-mentioned trident quassia weighed, Mountain breeze, ox rattan, Siberian cocklebur grass, scrawly handwriting, wear floricome, Common Camptotheca Fruit, waterlettuce herb, Semi-pinnated Brake Herb, the fleece-flower root, rush and fire fiber crops Benevolence, extract, filter through water respectively, and concentrate, obtain respective concentrate, it is standby;By obtained sucrose syrup with it is obtained dense Contracting liquid mixes, and adds 0.3g sodium benzoates and 0.08g ethyl hydroxy benzoates, and stirring is allowed to whole dissolvings, adds 15000mL water, stirs It is even, and be heated to seething with excitement, you can.
Embodiment 2:Treat the preparation of the psoriasic Chinese medicinal composition granules of stagnated heat of liver channel type
Trident quassia 13g, mountain breeze 14g, ox rattan 22g, Siberian cocklebur grass 8g, scrawly handwriting 18g are weighed respectively, wears floricome 14g, are liked Fruit 6g, waterlettuce herb 17g, Semi-pinnated Brake Herb 14g, fleece-flower root 10g, rush 4g, fructus cannabis 13g and sucrose 50g are set, it is standby;By thing The sucrose grinds first weighed, it is standby;By the above-mentioned trident quassia weighed, mountain breeze, ox rattan, Siberian cocklebur grass, scrawly handwriting, wear Floricome, Common Camptotheca Fruit, waterlettuce herb, Semi-pinnated Brake Herb, the fleece-flower root, rush and fructus cannabis, extract, filter through water respectively, and concentrate, obtain It is standby to respective concentrate;Obtained sucrose Icing Sugar is mixed with obtained concentrate, pelletized, is dried, you can.
Embodiment 3:Treat the preparation of the psoriasic Chinese medicinal composition capsules agent of stagnated heat of liver channel type
Trident quassia 17g is weighed respectively, mountain breeze 10g, ox rattan 18g, Siberian cocklebur grass 12g, scrawly handwriting 22g, wears floricome 10g, Common Camptotheca Fruit 10g, waterlettuce herb 13g, Semi-pinnated Brake Herb 10g, fleece-flower root 14g, rush 8g, fructus cannabis 17g and starch 30g, it is standby;Will The above-mentioned trident quassia weighed, mountain breeze, ox rattan, Siberian cocklebur grass, scrawly handwriting wear floricome, Common Camptotheca Fruit, waterlettuce herb, Semi-pinnated Brake Herb, what The tuber of multiflower knotweed, rush and fructus cannabis, extract, filter through water respectively, and concentrate, obtain respective concentrate, it is standby;By made from Concentrate is well mixed with starch, is pelletized, and is dried, is packed into capsule, you can.
Clinical test part
Clinical data counts:
By carrying out clinical observation, wherein male 42 to 100 stagnated heat of liver channel type psoriatics, women 58, suffer from Person's age, the course of disease was most short 20~120 days, and blood, routine urinalysis are without exception, is taken according to conditions of patients length between 25-60 year Two to three courses for the treatment of of medicine of the present invention, course for the treatment of at least one moon.
Curative effect judging standard:Recovery from illness:Skin lesion is disappeared or only stays filbert pigmentation spots completely, is occurred without new fash;It is aobvious Effect:Skin lesion is disappeared, and is occurred without new fash, and gargalesthesia substantially mitigates;Effectively:Skin lesion is disappeared more than 30%, is occurred without new fash, is itched Sense mitigates;It is invalid:Skin lesion is not disappeared, or has new fash to occur.
Clinical treatment counts, and clinical effective example, cures patient 63(63.0%);Effective example, improvement patient 34 (34.0%);Invalid patient 3(3%);By treatment, total effective rate 97%.Show that medicine of the present invention has higher clinic Treatment, it does not find obvious adverse reaction during Ureteral Calculus, shows that medicine of the present invention is safe and effective.
Specific case introduction
Case 1:Ms Zhang, 56 years old, stagnated heat of liver channel type psoriasis, symptom:Patient skin is dry, it is coarse, thicken, grab after scratching There is flush, skin damages, and scab is more, there is scratchiness, dry and hard excrement, scanty drak urine, red tongue with yellowish fur, veins string or chord number etc. Symptom, in anxious state of mind, itch aggravates.After 3 courses for the treatment of of medicine made of the present invention on probation, symptom disappears, and does not have bad anti- Should.
Case 2:Mr. Chen, 48 years old, stagnated heat of liver channel type psoriasis, symptom:Patient was because of the multiple tinea sample fash of whole body 1 year Remaining, since shank the year before without under obvious inducement, there is tinea sample fash in the patient, and boundary clear, the colour fading of pressure, there is play in affected part Strong scratchiness, have in distribution is dispersed in, fash is progressively crept up to thigh, buttocks, trunk.And fash constantly merges, with stern Portion, shank are obvious, it is seen that squamous papule and patch, dry skin, have the white scales of skin that peel off to come off.Medicine made of the present invention on probation After 4 courses for the treatment of, symptom disappears, and menses routine urianlysis is without exception.

Claims (5)

1. one kind treats the psoriasic Chinese medicine composition of stagnated heat of liver channel type, it is characterised in that includes the raw material of following parts by weight: 13 parts~17 parts of trident quassia, 10 parts~14 parts of mountain breeze, 18 parts~22 parts of ox rattan, 8 parts~12 parts of Siberian cocklebur grass, 18 parts of scrawly handwriting ~22 parts, wear 10 parts~14 parts of floricome, 6 parts~10 parts of Common Camptotheca Fruit, 13 parts~17 parts of waterlettuce herb, 10 parts~14 parts of Semi-pinnated Brake Herb, what 13 parts~17 parts of 10 parts~14 parts of the tuber of multiflower knotweed, 4 parts~8 parts of rush and fructus cannabis.
2. the described psoriasic Chinese medicine composition for the treatment of stagnated heat of liver channel type according to claim 1, it is characterised in that raw material Parts by weight are:15 parts of trident quassia, 12 parts of mountain breeze, 20 parts of ox rattan, 10 parts of Siberian cocklebur grass, 20 parts of scrawly handwriting, 12 parts of floricome is worn, 15 parts of 8 parts of Common Camptotheca Fruit, 15 parts of waterlettuce herb, 12 parts of Semi-pinnated Brake Herb, 12 parts of the fleece-flower root, 6 parts of rush and fructus cannabis.
3. the described psoriasic Chinese medicine composition for the treatment of stagnated heat of liver channel type according to claim 1, it is characterised in that raw material Parts by weight are:13 parts of trident quassia, 14 parts of mountain breeze, 22 parts of ox rattan, 8 parts of Siberian cocklebur grass, 18 parts of scrawly handwriting, 14 parts of floricome is worn, 13 parts of 6 parts of Common Camptotheca Fruit, 17 parts of waterlettuce herb, 14 parts of Semi-pinnated Brake Herb, 10 parts of the fleece-flower root, 4 parts of rush and fructus cannabis.
4. the described psoriasic Chinese medicine composition for the treatment of stagnated heat of liver channel type according to claim 1, it is characterised in that raw material Parts by weight are:17 parts of trident quassia, 10 parts of mountain breeze, 18 parts of ox rattan, 12 parts of Siberian cocklebur grass, 22 parts of scrawly handwriting, 10 parts of floricome is worn, 17 parts of 10 parts of Common Camptotheca Fruit, 13 parts of waterlettuce herb, 10 parts of Semi-pinnated Brake Herb, 14 parts of the fleece-flower root, 8 parts of rush and fructus cannabis.
5. the psoriasic Chinese medicine composition for the treatment of stagnated heat of liver channel type according to claim 1 or 2 or 3 or 4, its feature exist In:Mixture, granule or capsule is made in the Chinese medicine composition.
CN201410346836.7A 2014-07-21 2014-07-21 Treat the psoriasic Chinese medicine composition of stagnated heat of liver channel type Active CN104147274B (en)

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Citations (2)

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Publication number Priority date Publication date Assignee Title
CN103356868A (en) * 2013-07-19 2013-10-23 杨永林 Chinese medicinal capsule for treatment of psoriasis
CN103860843A (en) * 2014-03-19 2014-06-18 刘力 Chinese medicine ointment for treating psoriasis and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103356868A (en) * 2013-07-19 2013-10-23 杨永林 Chinese medicinal capsule for treatment of psoriasis
CN103860843A (en) * 2014-03-19 2014-06-18 刘力 Chinese medicine ointment for treating psoriasis and preparation method thereof

Non-Patent Citations (1)

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疏肝止痒汤治疗神经性皮炎临床观察;陈俊;《中国实用神经疾病杂志》;20100930;第13卷(第17期);第98页 *

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