CN104147230A - Externally-used medicinal liquor for treating ischemic heart disease - Google Patents
Externally-used medicinal liquor for treating ischemic heart disease Download PDFInfo
- Publication number
- CN104147230A CN104147230A CN201410424448.6A CN201410424448A CN104147230A CN 104147230 A CN104147230 A CN 104147230A CN 201410424448 A CN201410424448 A CN 201410424448A CN 104147230 A CN104147230 A CN 104147230A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- medicinal liquor
- wine
- ischemic heart
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to medicinal liquor and especially relates to and discloses externally-used medicinal liquor for treating ischemic heart disease. The medicinal liquor is prepared by soaking medicines including salviae miltiorrhizae, red peony roots, peach kernels, vaccaria segetalis, angelica sinensis, rhizoma chuanxiong, achyranthes bidentata, rhubarb, aconitum gymnandrum, angelica pubescens, prepared rehmannia roots, bupleurum and glycyrrhiza uralensis in liquor. According to traditional Chinese medicine theories, the medicinal liquor is prepared through a combination formula according to relationships among monarch drugs, minister drugs, assistant drugs and guide drugs on the basis of functions of the medicines so that the effects of the medicines can be achieved in a cooperation manner. The medicinal liquor has main effects of warming and freeing heart yang, activating blood and resolving stasis, and freeing collateral vessels and relieving pains. The medicinal liquor is mainly used for treating stable angina pectoris, venous thrombosis and the like.
Description
Technical field
The present invention relates to a kind of medicated wine, relate in particular to a kind of External apply medicinal wine for the treatment of ischemic heart desease.
Background technology
The ischemic heart desease cardiopathia that wins again, is a kind of modal heart disease, refers to coronary stricture, blood supply insufficiency and the myocardial dysfunction or the organic disease that cause.World Health Organization (WHO) is divided into 5 large classes by coronary heart disease: silent ischemia (latent coronary heart disease), angina pectoris, myocardial infarction, ischemic heart failure (ischemic heart desease) and 5 kinds of Clinical types of sudden death.Because the sickness rate of this medicine is high, harm is large, has developed more medicine and in clinical use, concrete medication can be divided into: Pimobendane in integrative therapy: nitrate esters medicine, as sorbitrate etc., can improve blood supply; Beta-blocker: as metoprolol, atenolol etc., can decreased heart rate, reduce myocardial oxygen consumption; Adjust hypolipidemic medicine: as simvastatin, lovastatin, pravastatin, atorvastatin, lipanthyl etc.; Antiplatelet drug and reduce blood viscosity medicine: as aspirin etc.In addition also has miscellaneous Chinese traditional compound medicine with blood circulation promoting and blood stasis dispelling promoting the circulation of QI to relieve pain effect, as SUXIAO JIUXIN WAN, DIAOXINXUE KANG, ginseng pine heart tonifying capsule etc.
But all there are some defects in said medicine,, may there is anaphylaxis, digestive tract reaction, nervous system reaction in long-term taking, also can cause the untoward reaction such as menoxenia, hematuria, some drugs, because having decreased heart rate or antihypertensive effect, is not suitable for bradycardia or hypotensive yet.And the Chinese patent medicine of some treatment coronary heart disease also has the side effect that is similar to Western medicine, also have the contained component of some Chinese patent medicines itself to cause new infringement to cardiac function, as easy in the Borneolum Syntheticum in SUXIAO JIUXIN WAN impairment of YANG consumption gas, life-time service can make cardiac function weaken etc. on the contrary.Not only there is above-mentioned defect in above medicine, after patient's drug withdrawal, the state of an illness also there will be repeatedly, and life-time service, also can make patient produce toleration to medicine, and not reach the effect for the treatment of.Therefore mostly cure the symptoms, not the disease, can not fundamentally play therapeutical effect.
Again because Ischemic Heart Disease majority also can be with other cardiac symptoms such as arrhythmia, heart failure, cardiopalmus, myocarditiss, or with as diseases such as pulmonary heart disease, emphysema, thereby often all can take two or more medicine simultaneously, this not only increases patient's misery of taking medicine, also can bring more drug side effect, also increase the financial burden of sufferer.
Summary of the invention
The object of the invention is to overcome the shortcoming of said medicine, a kind of External apply medicinal wine for the treatment of ischemic heart desease is provided.
The technical scheme that realizes the object of the invention is:
Treat an External apply medicinal wine for ischemic heart desease, this External apply medicinal wine is that the raw material by following parts by weight soaks and makes in wine: 190～210 parts of Radix Salviae Miltiorrhizaes, 190～210 parts of Radix Paeoniae Rubra, 142～158 parts, Semen Persicae, 142～158 parts of Semen Vaccariae, 190～210 parts of Radix Angelicae Sinensis, 190～210 parts of Rhizoma Chuanxiongs, 190～210 parts of Radix Achyranthis Bidentataes, 76～84 parts of Radix Et Rhizoma Rhei, 95～105 parts of Herba Lycopi, 95～105 parts of Radix Angelicae Pubescentiss, 142～158 parts of Radix Rehmanniae Preparata, 142～158 parts of Radix Bupleuri, 48～52 parts, Radix Glycyrrhizae.
Preferably: described in mark meter, wine is 15000 parts by weight.
Preferably: described wine is the Chinese liquor of 60 degree.
Preferably: described External apply medicinal wine is soaked and makes at least 14 days in wine by described raw material.
In pharmaceutical formulation of the present invention, each flavour of a drug have following effect:
Radix Salviae Miltiorrhizae: bitter in the mouth, slightly warm in nature, enters the heart, Liver Channel.Energy blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, evacuation of pus, pain relieving.Control angina pectoris, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.
Radix Paeoniae Rubra: sour in the mouth is bitter, cool in nature, enters liver, spleen channel.Energy clots absorbing, pain relieving, removing heat from blood, detumescence.Control stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle.
Semen Persicae: bitter but sweet flavor, property is flat, enters the heart, liver, large intestine channel.Energy blood stasis removing and clots absorbing, moisturizes laxation.Control calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.
Semen Vaccariae: bitter in the mouth, property is flat, enters liver, stomach warp.Can promoting the circulation of blood stimulate the menstrual flow, expedite the emergence of stimulating milk secretion, promoting blood circulation and detumescence sore.For blood stasis lump and sore and toxic.Control galactostasis, difficult labour, stranguria with blood, incised wound is hemorrhage.
Radix Angelicae Sinensis: sweet in the mouth is pungent, warm in nature, enter the heart, liver, spleen channel.Energy benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down; Menoxenia, amenorrhea stomachache, metrorrhagia.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature, enter liver, gallbladder meridian.Energy activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Control air-cooled headache revolve dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, ulcer sores.
Radix Achyranthis Bidentatae: sweet in the mouth picric acid, property is flat, enters liver, kidney channel.Energy dissipating blood stasis blood, subduing inflammation.Control gonorrhea, hematuria, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury.
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature, enter stomach, large intestine, Liver Channel.The poison that can purge heat, removing mass is stagnant, clots absorbing blood.Control excess-heat constipation, delirium is sent out holder, food stagnation feeling of fullness, dysentery is from the beginning of, tenesmus ， lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, also urinates, carbuncle and ulcer toxic swelling, furuncle, burn.Purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation., jaundice due to damp-heat not well for excess-heat constipation, stagnant stomachache, dysentery.
Herba Lycopi: bitter in the mouth is pungent, slightly warm in nature, enters liver, spleen channel.Can invigorate blood circulation, row water.Control amenorrhea ， mass in the abdomen, the stagnant stomachache of the stasis of blood in puerperal, body and face edema, injury from falling down, incised wound, carbuncle.
Radix Angelicae Pubescentis: acrid in the mouth is bitter, warm in nature, enters kidney, urinary bladder channel.Can dispel the wind, victory is wet, cold expelling, pain relieving.Control anemofrigid-damp arthralgia, soreness of waist and knee joint, trick spasm and pain, chronic tracheitis, headache, toothache.
Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature, enters liver, kidney channel.Energy YIN nourishing, enriches blood.Control deficiency of YIN insufficiency of blood, waist knee flaccidity, chronic cough hectic fever due to YIN-deficiency, seminal emission, metrorrhagia, menoxenia, quenches one's thirst, frequency of micturition, deafness, blurred vision.
Radix Bupleuri: bitter in the mouth, cool in nature, enter liver, gallbladder meridian.Energy reconciling superficies and interior, soothing the liver, yang invigorating.Control alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, diarrhea proctoptosis, uterine prolapse.
Radix Glycyrrhizae: sweet in the mouth, property is flat, enters spleen, stomach, lung meridian.Energy and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.Control laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.
Beneficial effect of the present invention:
Medicated wine of the present invention, according to Chinese medical theory, according to the different efficacies of each flavour of a drug, carries out composition of prescription according to the relation of monarch, and in the side of making, all medicines are worked in coordination with mutually performance effect.The main effect of medicated wine of the present invention is warming and activating heart-YANG, blood circulation promoting and blood stasis dispelling, and removing obstruction in the collateral to relieve pain, cures mainly stable angina pectoris, phlebothrombosis etc.
The present invention adopts topical administration mode, has avoided the oral GI irritation causing and patient dislike, worry, and medicine for external use absorbs through skin, non-stimulated to rectum.Local application directly acts on diseased region, and medicine can well be absorbed, more remarkable effect.
Formulation of the present invention is reasonable, and compatibility is rigorous, through long-term clinical verification, determined curative effect.
The present invention adopts natural Chinese medicine, and raw material sources are extensive, practical and convenient.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is done to further detailed elaboration, but embodiments of the present invention are not limited to the scope that embodiment represents.These embodiment are only for the present invention is described, but not for limiting the scope of the invention.In addition, after reading content of the present invention, those skilled in the art can do various modifications to the present invention, and these equivalent variations fall within appended claims limited range of the present invention equally.
Embodiment 1
According to following weight (gram) proportioning gets needed raw material:
Radix Salviae Miltiorrhizae 190 Radix Paeoniae Rubra 190 Semen Persicae 142 Semen Vaccariae 142 Radix Angelicae Sinensis 190 Rhizoma Chuanxiong 190 Radix Achyranthis Bidentatae 190 Radix Et Rhizoma Rhei 76 Herba Lycopi 95 Radix Angelicae Pubescentis 95 Radix Rehmanniae Preparata 142 Radix Bupleuri 142 Radix Glycyrrhizaes 48.
Above-mentioned raw materials is positioned over drug immersion in 15 kilogram of 60 degree Chinese liquor, and sealing is soaked 14 days, obtains medicated wine.
Embodiment 2
According to following weight (gram) proportioning gets needed raw material:
Radix Salviae Miltiorrhizae 200 Radix Paeoniae Rubra 200 Semen Persicae 150 Semen Vaccariae 150 Radix Angelicae Sinensis 200 Rhizoma Chuanxiong 200 Radix Achyranthis Bidentatae 200 Radix Et Rhizoma Rhei 80 Herba Lycopi 100 Radix Angelicae Pubescentis 100 Radix Rehmanniae Preparata 150 Radix Bupleuri 150 Radix Glycyrrhizaes 50.
Above-mentioned raw materials is positioned over drug immersion in 15 kilogram of 60 degree Chinese liquor, and sealing is soaked 20 days, obtains medicated wine.
Embodiment 3
According to following weight (gram) proportioning gets needed raw material:
Radix Salviae Miltiorrhizae 210 Radix Paeoniae Rubra 210 Semen Persicae 158 Semen Vaccariae 158 Radix Angelicae Sinensis 210 Rhizoma Chuanxiong 210 Radix Achyranthis Bidentatae 210 Radix Et Rhizoma Rhei 84 Herba Lycopi 105 Radix Angelicae Pubescentis 105 Radix Rehmanniae Preparata 158 Radix Bupleuri 158 Radix Glycyrrhizaes 52.
Above-mentioned raw materials is positioned over drug immersion in 15 kilogram of 60 degree Chinese liquor, and sealing is soaked 25 days, obtains medicated wine.
Below in conjunction with concrete data, beneficial effect of the present invention is described further:
In JIUYUE, 2013 to the 2014 54 routine Stable Angina Pectoris that year March, Wo section was in hospital, on the basis of routine medication, be conventional anticoagulant, blood vessel dilating, tune fat, control the treatments such as blood pressure and blood glucose, adopt embodiment 2 preparation gained warming and activating heart-YANG, blood circulation promoting and blood stasis dispelling, the prescription external application acupuncture point of removing obstruction in the collateral to relieve pain is scalded and is pressed treatment, and applies SPSS19.0 software the data obtained is carried out to statistical analysis, observes its treatment curative effect.
Evaluation of clinical curative effect:
Effective: after treatment, patient's angina pectoris attacks disappears or attack times minimizing degree >80% substantially, or nitroglycerine tablets consumption reduces degree >80%, electrocardiogram check T involves ST section and recovers normal, and exercise test is negative.
Effective: after treatment, patient's angina pectoris obviously improves, angina pectoris attacks number of times reduces degree >50%, and electrocardiogram check ST section is low flat, and T ripple phenomena of inversion obviously improves.
Invalid: after one course for the treatment of of treatment, patient's angina pectoris attacks number of times reduces degree and do not reach 50%, or nitroglycerine tablets consumption reduces degree and do not reach 50%, and electrocardiogram check T involves ST section not to be improved.
Total effective rate=[(effective number of cases+effective number of cases)/total number of cases] * 100%.
Through observational study, after this group patient treatment, obvious effective rate is 21/54 (38.89%), effective percentage is 30/54 (55.56%), inefficiency is 3/54 (5.56%), total effective rate is 51/54 (94.44%).Relatively front with treatment, after treatment, patient's thrombin time (PT) obviously increases, and by treatment, front 13.1 ± 2.2s rises to 15.8 ± 2.7s; Activated partial thromboplastin time (APTT) also obviously increases, and by treatment, front 29.3 ± 4.7s rises to 38.6 ± 6.2s; DDi (D-dimer) significantly reduces, and by treatment, front 5.12 ± 0.98mg/L drops to 1.47 ± 0.31mg/L.This prescription has good tune fat, anticoagulant, fibrinolysis enhancing, improves microcirculation, reduces peripheral vascular resistance, improves the effects such as myocardial ischemia.This therapeutic scheme is safe and effective, in therapeutic process, without bleeding episode and adverse cardiac events, occurs, and is worthy of popularization.
Claims (4)
1. an External apply medicinal wine for the treatment of ischemic heart desease, is characterized in that: described External apply medicinal wine is that the raw material by following parts by weight soaks and makes in wine: 190～210 parts of Radix Salviae Miltiorrhizaes, 190～210 parts of Radix Paeoniae Rubra, 142～158 parts, Semen Persicae, 142～158 parts of Semen Vaccariae, 190～210 parts of Radix Angelicae Sinensis, 190～210 parts of Rhizoma Chuanxiongs, 190～210 parts of Radix Achyranthis Bidentataes, 76～84 parts of Radix Et Rhizoma Rhei, 95～105 parts of Herba Lycopi, 95～105 parts of Radix Angelicae Pubescentiss, 142～158 parts of Radix Rehmanniae Preparata, 142～158 parts of Radix Bupleuri, 48～52 parts, Radix Glycyrrhizae.
2. the External apply medicinal wine for the treatment of ischemic heart desease according to claim 1, is characterized in that: described in mark meter, wine is 15000 parts by weight.
3. the External apply medicinal wine for the treatment of ischemic heart desease according to claim 1, is characterized in that: described wine is the Chinese liquor of 60 degree.
4. the External apply medicinal wine for the treatment of ischemic heart desease according to claim 1, is characterized in that: described External apply medicinal wine is soaked and makes at least 14 days in wine by described raw material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410424448.6A CN104147230B (en) | 2014-08-26 | 2014-08-26 | A kind of External apply medicinal wine for the treatment of ischemic heart desease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410424448.6A CN104147230B (en) | 2014-08-26 | 2014-08-26 | A kind of External apply medicinal wine for the treatment of ischemic heart desease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104147230A true CN104147230A (en) | 2014-11-19 |
| CN104147230B CN104147230B (en) | 2016-03-09 |
Family
ID=51872994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410424448.6A Active CN104147230B (en) | 2014-08-26 | 2014-08-26 | A kind of External apply medicinal wine for the treatment of ischemic heart desease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104147230B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670824A (en) * | 2012-05-09 | 2012-09-19 | 成都绿迪科技有限公司 | Traditional Chinese medicine preparation for treating coronary heart disease by oral administration |
| CN103933474A (en) * | 2014-04-10 | 2014-07-23 | 成都中医药大学 | Medicinal composition for treating coronary heart disease, as well as preparation method and application thereof |
-
2014
- 2014-08-26 CN CN201410424448.6A patent/CN104147230B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670824A (en) * | 2012-05-09 | 2012-09-19 | 成都绿迪科技有限公司 | Traditional Chinese medicine preparation for treating coronary heart disease by oral administration |
| CN103933474A (en) * | 2014-04-10 | 2014-07-23 | 成都中医药大学 | Medicinal composition for treating coronary heart disease, as well as preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104147230B (en) | 2016-03-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1061854C (en) | Medicinal preparation for treatment and prevention of gynopathy | |
| CN103520654B (en) | A kind of Chinese medicine composition being used for the treatment of knee osteoarthritis and preparation method thereof | |
| CN103156972B (en) | Traditional Chinese medicine combination for treating fracture, hairline fracture and traumatic injury | |
| CN101391077B (en) | Preparation method of traditional Chinese medicine for treating chronic pelvic inflammatory disease | |
| CN102258658A (en) | Plaster for invigorating blood circulation and relieving pain | |
| CN104873631A (en) | Traditional Chinese medicinal composition for treating bone diseases, preparation method of traditional Chinese medicinal composition and bone disease therapeutic apparatus | |
| CN104258304A (en) | Medicated wine for meridian unblocking, wind dispelling, collaterals activating and pain relieving | |
| CN102657795A (en) | Traditional Chinese medicine preparation for promoting postoperative incision healing | |
| CN105031013A (en) | Medicine for treating lumbar vertebrae bone hyperplasia and preparation method thereof | |
| CN104587206A (en) | Medicament for treating bedsore and preparation method of medicament | |
| CN102416049B (en) | Small square type rheumatoid swelling diminishing and pain eliminating plaster and preparation method thereof | |
| CN104800610A (en) | Traditional Chinese medicine preparation for treating Parkinson's disease and preparation method thereof | |
| CN105148235A (en) | Traditional Chinese medicine combination treating postpartum hemorrhage | |
| CN104147230B (en) | A kind of External apply medicinal wine for the treatment of ischemic heart desease | |
| CN104189714A (en) | Traditional Chinese medicine capsule for treating coronary heart disease | |
| CN109908245A (en) | It is a kind of for treating the Chinese medicine composition of neck-shoulder pain, lumbago and leg pain disease | |
| CN105687962A (en) | Electuary capable of treating atherosclerosis of coronary artery and preparation method thereof | |
| CN103356951B (en) | A kind of Chinese medicine composition for the treatment of cardiac blood supply deficiency | |
| CN108159276A (en) | A kind of fumigation liquid and preparation method thereof and application method | |
| CN102406789B (en) | Plaster for treating cervical spondylosis | |
| CN105362944A (en) | Traditional Chinese medicine ointment for treating orthopedics sprain and contusion | |
| CN104873858A (en) | Traditional Chinese medicine composition for treating functional dysmenorrheal | |
| CN105079487A (en) | Traditional Chinese medicine composition for treating heat stranguria | |
| CN106619852A (en) | Traditional Chinese medicine lavipeditum life cultivation and health preservation prescription with effects of warming channels and dispersing cold, and dredging grain of skin and texture of the subcutaneous flesh | |
| CN104740193A (en) | Traditional Chinese medicine composition for treating neck-shoulder muscle strain syndrome and preparation method of traditional Chinese medicine composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190131 Address after: No. 52 Botanical Road, Qingxiu District, Nanning City, Guangxi Zhuang Autonomous Region, 530021 Patentee after: 923 Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army Address before: 530021 Department of Cardiology, No. 52 Botanical Road, Nanning City, Guangxi Zhuang Autonomous Region, 303 Hospital of Chinese People's Liberation Army Patentee before: Gong Chaoqi |