CN104147056B - Composition containing bromhexine hydrochloride - Google Patents
Composition containing bromhexine hydrochloride Download PDFInfo
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- CN104147056B CN104147056B CN201410400645.4A CN201410400645A CN104147056B CN 104147056 B CN104147056 B CN 104147056B CN 201410400645 A CN201410400645 A CN 201410400645A CN 104147056 B CN104147056 B CN 104147056B
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- bromhexine hydrochloride
- composition
- moringa oleifera
- moringa
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Abstract
The invention discloses a composition containing bromhexine hydrochloride. The composition comprises the following components by weight: 1-3 parts of bromhexine hydrochloride and 1-3 parts of Moringa oleifera. The composition is prepared by washing Moringa oleifera with water, drying, crushing, and then mixing Moringa oleifera with bromhexine hydrochloride by a certain weight ratio, and sterilizing. Bromhexine hydrochloride has of good curative effect in the treatment of asthma; however, as a Western medicine, bromhexine hydrochloride inevitably has side effect, and in order to reduce the impact of side effects, the Moringa oleifera is added to bromhexine hydrochloride in the composition provided by the invention; and the obtained composition has significant effect on the treatment of asthma. Combination of bromhexine hydrochloride and Moringa oleifera has a synergistic therapeutic effects; in the same amount of dosage, the treatment effect of the composition is better than that of bromhexine hydrochloride, so as to greatly reduce the amount of bromhexine hydrochloride and reduce the side effects caused by bromhexine hydrochloride.
Description
Technical field
The present invention relates to a kind of compositions of hydrochloric bromhexine.
Background technology
Bronchial asthma (abbreviation asthma) be act on by sensitizing agent or non-sensitizing agent bronchial muscular spasm that body causes, the pathological change such as myxedema, mucous secretion increase, by various kinds of cell, the particularly chronic airway allergic inflammation that participates in of the inflammatory cell such as eosinophilic granulocyte (EOS), mastocyte, T lymphocyte, neutrophilic granulocyte (NEUT) and human airway epithelial cells and various kinds of cell component thereof, can occur in the crowd of age groups, be the respiratory tract disease with high incidence and high mortality.The pathogenic factor of asthma is complicated, is that some factor being subject to inside and outside on the basis of heredity excites and occurs mostly.
Existing asthma Comprehensive Treatment technology also exists following shortcoming:
1. Western medicine curative effect is quick, but the drug variety that Comprehensive Treatment uses simultaneously is many, method is loaded down with trivial details, and wherein the side effect of many Western medicine is large.
2. Chinese medicine instructions of taking trouble, onset is slow.
Moringa is Moringaceae Moringa plant Moringa oleifera, is a kind of tropical plants having unique economic to be worth.Blade and the fruit of Moringa are rich in several mineral materials, vitamin and health care and medicinal chemistry composition, as vegetable and food, can have extra-nutrition and Dietotherapy health function, also may be used for preventing and treating some diseases.It is generally acknowledged that Moringa has to bring down a fever, antiinflammatory, calculus, diuresis, blood pressure lowering, pain relieving, heart tonifying, urge the functions such as wish.India and African country are usually used in the various diseases such as treatment diabetes, hypertension, cardiovascular diseases, obesity, dermatosis, ophthalmic, hypoimmunity, vitamin C deficiency, anemia, arthritis, rheumatism, digestive system tumor.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of compositions of hydrochloric bromhexine is provided.
To achieve these goals, the present invention adopts following technical scheme:
A compositions for hydrochloric bromhexine, is made up of the component of following weight portion:
Bisolvon 1-3, Moringa 1-3.
Its preferred parts by weight are:
Bisolvon 1, Moringa 1.
The preparation method of above-mentioned composition comprises the steps: Moringa water to clean, and dry, pulverize, then mixes by ratio of weight and the number of copies with Bisolvon, sterilizing and get final product.
Compared with prior art, the present invention has following beneficial effect: Bisolvon has the curative effect of good treatment asthma, then as a kind of Western medicine, it is unavoidably with side effect, in order to reduce the impact of side effect, compositions of the present invention by adding Moringa in Bisolvon, and resulting composition has significant effect to treatment asthma.The combination of Bisolvon and Moringa has synergistic therapeutic action, and when equal consumption, its therapeutic effect is better than Bisolvon, thus greatly can reduce the consumption of Bisolvon, thus can reduce the side effects that Bisolvon brings.
Detailed description of the invention
Embodiment 1:
By Moringa use water clean, dry, pulverize, then with Bisolvon by weight 1:1 mix, namely sterilizing obtains pharmaceutical composition.
Embodiment 2:
By Moringa use water clean, dry, pulverize, then with Bisolvon by weight 1:3 mix, namely sterilizing obtains pharmaceutical composition.
Embodiment 3: activity experiment
Embodiment 1 compositions and the Experiment on therapy of Bisolvon to asthma the results are shown in Table 1-3.
Table 1 causes the impact (X ± SD, n=6) of breathing heavily on histamine spray
Table 2 is on the impact (X ± SD, n=6) of the in vitro complete tracheal smooth muscle of mice
Table 3 pair mice ammonia draws the antitussive effect (X ± SD) coughed
Note: compare with distilled water matched group, * P<0.05, * * P<0.01.
From table 1-3, embodiment 1 compositions and Bisolvon all have good therapeutic effect to asthma, and in same consumption situation, the therapeutic effect of the compositions of embodiment 1 is better than Bisolvon.
Embodiment 4: with reference to embodiment 3, embodiment 1 is replaced with the compositions of embodiment 2, compositions and the Bisolvon of result display embodiment 2 all have good therapeutic effect to asthma, and in same consumption situation, the therapeutic effect of the compositions of embodiment 2 is better than Bisolvon.
Claims (1)
1. a compositions for hydrochloric bromhexine, is characterized in that being made up of the component of following weight portion:
Bisolvon 1, Moringa 1;
Preparation method comprises the steps: Moringa water to clean, and dry, pulverize, then mixes by ratio of weight and the number of copies with Bisolvon, sterilizing and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410400645.4A CN104147056B (en) | 2014-08-14 | 2014-08-14 | Composition containing bromhexine hydrochloride |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410400645.4A CN104147056B (en) | 2014-08-14 | 2014-08-14 | Composition containing bromhexine hydrochloride |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104147056A CN104147056A (en) | 2014-11-19 |
| CN104147056B true CN104147056B (en) | 2015-07-08 |
Family
ID=51872820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410400645.4A Active CN104147056B (en) | 2014-08-14 | 2014-08-14 | Composition containing bromhexine hydrochloride |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104147056B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101836994A (en) * | 2010-06-01 | 2010-09-22 | 哈尔滨誉衡药业股份有限公司 | Compound oral preparation of cefaclor and bromhexine and preparation method thereof |
| CN102870933A (en) * | 2012-10-10 | 2013-01-16 | 祖延霞 | Health-care tea |
| CN103565758A (en) * | 2013-10-15 | 2014-02-12 | 海南卫康制药(潜山)有限公司 | Bromhexine hydrochloride composition freeze-dried powder for injection |
-
2014
- 2014-08-14 CN CN201410400645.4A patent/CN104147056B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101836994A (en) * | 2010-06-01 | 2010-09-22 | 哈尔滨誉衡药业股份有限公司 | Compound oral preparation of cefaclor and bromhexine and preparation method thereof |
| CN102870933A (en) * | 2012-10-10 | 2013-01-16 | 祖延霞 | Health-care tea |
| CN103565758A (en) * | 2013-10-15 | 2014-02-12 | 海南卫康制药(潜山)有限公司 | Bromhexine hydrochloride composition freeze-dried powder for injection |
Non-Patent Citations (1)
| Title |
|---|
| 氨溴索和溴己新佐治慢性支气管炎急性发作的疗效比较;刘春华;《现代诊断与治疗》;20130731;第24卷(第9期);2004页 * |
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| Publication number | Publication date |
|---|---|
| CN104147056A (en) | 2014-11-19 |
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Effective date of registration: 20221115 Address after: No.6 Dongbo Road, East District, Guangzhou Economic and Technological Development Zone, Guangdong 510000 Patentee after: GUANGZHOU YIPINHONG PHARMACEUTICAL Co.,Ltd. Patentee after: GUANGDONG ZERUI PHARMACEUTICAL Co.,Ltd. Patentee after: Guangzhou Lianrui Pharmaceutical Co.,Ltd. Patentee after: Guangzhou Runlin Pharmaceutical Technology Co.,Ltd. Patentee after: Euphorbia Biological Medicine Co.,Ltd. Address before: Building 1, No. 6, Dongbo Road, Guangzhou Economic and Technological Development Zone, Guangzhou, Guangdong 510765 Patentee before: GUANGZHOU YIPINHONG PHARMACEUTICAL Co.,Ltd. |