CN104127508B - For treating pharmaceutical composition and the preparation method of prolapse of lumbar intervertebral disc - Google Patents
For treating pharmaceutical composition and the preparation method of prolapse of lumbar intervertebral disc Download PDFInfo
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Abstract
The invention provides a kind of for pharmaceutical composition treating prolapse of lumbar intervertebral disc and preparation method thereof, by pharmaceutical composition prepared by Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum compatibility, in treatment prolapse of lumbar intervertebral disc, there is obvious action, and not finding obvious adverse reaction after using, safety is high.
Description
Technical field
The invention belongs to field of traditional Chinese, be specifically related to a kind of for pharmaceutical composition treating prolapse of lumbar intervertebral disc and preparation method thereof.
Background technology
Prolapse of lumbar intervertebral disc, has another name called Annulus Fibrosus of Lumbar Intervertebral Discs and breaks disease or lumbar nucleus pulposus herniation.It is that after Anular disruption, Nucleus pulposus compressing spinal nerve root causes a kind of common disease of lumbago and skelalgia, multiple be born in 20-45 year person between twenty and fifty, wherein male is more than women.Most of patients has trauma history in various degree, waist bend and stretch spinning movement due to posture and tension unbalanced, patient's lower limb are made to be in when stretching to bend over to remove and carry weight and hold thing along y direction and rotate, intervertebral disc front portion pressure increases, extrude intervertebral disc backward, under rotation is milled, cause Anular disruption and vertebral pulp backward or protruding outside afterwards.The regression of intervertebral disc is also a major reason of prolapse of lumbar intervertebral disc, the generation of prolapse of lumbar intervertebral disc is many in intervertebral disc self degeneration, on the basis that fibrous ring becomes fragile, can because of caused by an acute waist wound or long-term chronic strain, annulus fibrosus disci intervertebralis is caused to break, Nucleus pulposus, compressing spinal nerve root causes lumbago and skelalgia.
Prolapse of lumbar intervertebral disc is recognized by the traditional Chinese medical science very early, dialectical analysis is carried out according to its pathogeneticing characteristic, classical symptom, prolapse of lumbar intervertebral disc belongs to the sick category such as Chinese medicine " lumbago ", " arthromyodynia ", just have as far back as " Plain Questions thorn a lumbago section " " belt vessel makes us lumbago; can not pitching; faces upward and then probably falls forward, weight lifting hinder waist " description.This disease is relevant with factors such as congestion, wind and cold, rheumatism, deficiency of the liver and kindey." General Treatise on the Cause and Symptoms of Diseases soldier wait " propose " people of husband's wound, kidney qi is deficient, and the main waist foot of kidney; it is through passing through kidney network ridge; ailment said due to cold or exposure is taken advantage of a weak point in opponent's defence, and soldier enters kidney channel, therefore finally however lumbago " etiology and pathogenesis, point out " deficiency of kidney-QI; done also by ailment said due to cold or exposure, impairment caused by overstrain is then suffered from a deficiency of the kidney, and void is then by air-cooled; air-cooled friendship with vital qi is striven, therefore waist foot pain " simultaneously.
Modern Chinese medicine thinks that the cause of disease main manifestations causing prolapse of lumbar intervertebral disc is syndrome of static blood blocking collaterals, specifically has the following aspects: or natural endowment is not enough, and fatigue is too in addition；Or weakness due to chronic disease or worn with age or intemperate sexual intercourse are so that caused by liver and kidney deficiency, are difficult Ru Yangjinmai and send out lumbago and skelalgia；Or because of traumatic injury wound, or because of prolonged illness, QI-blood circulation is not smooth, or position is not just, waist undue force, gets rid of gas sprain and contusion, causes that meridian qi and blood retardance is obstructed, blood stasis all can be made to stay pain occurs in waist；Or because of the damp that is affected by the cold, with the passing of time, QI and blood is not smooth, caused by the blood stasis of blood is stagnant for evil resistance passages through which vital energy circulates.The main clinical manifestation of prolapse of lumbar intervertebral disc obstruction of collaterals by blood stasis disease is: lumbago such as thorn, localized pain, gently then pitching inconvenience, heavy then because bitterly then not changing one's position, sore spot tenderness, with skelalgia, numb limbs and tense tendons, aversion to wind and cold, meet cold increasing the weight of, happiness Wen Xinuan etc., purplish tongue, or have ecchymosis, hesitant pulse.
At present, the method treating prolapse of lumbar intervertebral disc mainly has the methods such as physical therapy, operative treatment and Drug therapy.But existing physical therapy, operative treatment and Drug therapy there is also following many deficiencies, as: therapeutic method of surgery costly, and increases the misery of patient；Although physical therapy method can alleviate the misery of patient, prolapse of lumbar intervertebral disc can not be effected a radical cure；Western medicine prolapse of lumbar intervertebral disc with easing pain and diminishing inflammation, can relief of symptoms, but side effect is bigger.Again owing to being confirmed by a large amount of clinical practice experiences, only only a few patients with lumbar disc herniation must carry out outside operative treatment, and most patients adopt Chinese traditional treatment method to obtain good curative effect, and obtain clinical accreditation.Therefore the present invention provides a kind of pharmaceutical composition for treating prolapse of lumbar intervertebral disc obstruction of collaterals by blood stasis disease and preparation method thereof.
Summary of the invention
For this, the technical problem to be solved is in that to provide a kind of pharmaceutical composition for treating prolapse of lumbar intervertebral disc especially prolapse of lumbar intervertebral disc syndrome of static blood blocking collaterals, reaches the purpose for the treatment of both the principal and secondary aspects of a disease.
The preparation method that the present invention further discloses described pharmaceutical composition.
For solving above-mentioned technical problem, a kind of pharmaceutical composition for treating prolapse of lumbar intervertebral disc of the present invention, the crude drug of described pharmaceutical composition consists of: Radix Dipsaci 120-180 weight portion, Caulis Piperis Kadsurae 100-150 weight portion, Caulis Sinomenii 100-150 weight portion, Herba speranskiae tuberculatae 120-180 weight portion, Herba Lycopodii 100-150 weight portion, Flos Carthami 80-120 weight portion, Lignum Sappan 80-120 weight portion and Halitum 10-50 weight portion.
Described pharmaceutical composition, the crude drug of described pharmaceutical composition consists of: Radix Dipsaci 150 weight portion, Caulis Piperis Kadsurae 120 weight portion, Caulis Sinomenii 120 weight portion, Herba speranskiae tuberculatae 150 weight portion, Herba Lycopodii 120 weight portion, Flos Carthami 100 weight portion, Lignum Sappan 100 weight portion and Halitum 30 weight portion.
The invention provides a kind of method preparing above-mentioned pharmaceutical composition, comprise the steps:
Take described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding according to selected parts by weight to extract, merge and filter gained extracting solution, by gained filtrate reduced in volume to obtaining clear paste, after standing and filtering, taking filtrate and add customary adjuvant, conventionally technique makes acceptable exterior-applied formulation clinically.
Preferably, described preparation method, comprise the steps:
Take described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding according to selected parts by weight to extract 1-3 time, add the water of 10-20 times of drug weight every time, decoct 1-3 hour every time, merge and filter gained extracting solution, it is the clear paste of 1.05-1.10 by gained filtrate reduced in volume to 60 DEG C relative density, after standing and filtering, taking filtrate and add customary adjuvant, conventionally technique makes acceptable spray, liniment, unguentum, paste, lotion, patch or fumigation and washing agent clinically.
More preferably, described preparation method, comprise the steps:
Take described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding according to selected parts by weight to extract 2 times, first time adds the water of 15 times of drug weight, decoct 1.5 hours, second time adds the water of 10 times of drug weight, decoct 1.5 hours, merge and filter gained extracting solution, it is the clear paste of 1.08 by gained filtrate reduced in volume to 60 DEG C relative density, after standing and filtering, taking filtrate and add customary adjuvant, conventionally technique makes acceptable spray, liniment, unguentum, paste, lotion, patch or fumigation and washing agent clinically.
Preferably, described dosage form is fumigation and washing agent.
The invention provides a kind of clinically-acceptable external preparation being made up of above-mentioned pharmaceutical composition addition customary adjuvant, conventionally technique.
Preferably, described external preparation is acceptable spray, liniment, unguentum, paste, lotion, patch or fumigation and washing agent clinically.
It is furthermore preferred that described external preparation is fumigation and washing agent.
The invention provides a kind of fumigation and washing agent for treating prolapse of lumbar intervertebral disc, by aforementioned pharmaceutical compositions, adding 2-5 parts by weight sodium is adjuvant, and conventionally technique is prepared from.
The invention provides a kind of method preparing described fumigation and washing agent, the step that described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding extract is taken including according to selected parts by weight, merge gained extracting solution and filter, by gained filtrate reduced in volume to clear paste, after standing and filtering, add the sodium benzoate of selected parts by weight so as to dissolve, add purified water and adjust volume, to obtain final product.
The invention provides a kind of described pharmaceutical composition purposes in the medicine of preparation treatment prolapse of lumbar intervertebral disc.
The purposes of described pharmaceutical composition, described prolapse of lumbar intervertebral disc is prolapse of lumbar intervertebral disc syndrome of static blood blocking collaterals.
Pharmaceutical composition for treating prolapse of lumbar intervertebral disc of the present invention, by pharmaceutical composition prepared by Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum compatibility, in treatment prolapse of lumbar intervertebral disc, there is obvious action, especially in prolapse of lumbar intervertebral disc syndrome of static blood blocking collaterals, and not finding obvious adverse reaction after using, safety is high.
Experimental example
The clinical observation of traditional Chinese medicine composition for treating prolapse of lumbar intervertebral disc of the present invention
1, data and method
Clinical data: 254 examples are suffered from the patient of prolapse of lumbar intervertebral disc and carry out clinical observation by the present invention.
The evaluation criterion of clinical therapeutic efficacy is:
(1) clinical cure: original transference cure；
(2) effective: original symptom partial disappearance；
(3) invalid: symptom and sign is unchanged.
Medication: fumigation and washing agent prepared by embodiment 1 is placed in fumigation treatment couch container, adds water to 1500-2000ml.Patient lies supine controls on bed in smoked, and after utilizing medicine to add water boil, the stifling affected part of produced medicine steam is to treat disease, and additional manual adjustable electric-controlled on-off control temperature.Once a day, each 30 minutes, 3 weeks be a course for the treatment of.
2, therapeutic outcome
After using 2-3 the course for the treatment of of medicine composite for curing example patient of the embodiment of the present invention 1 preparation, observe the therapeutic outcome of patients with lumbar disc herniation, found that, wherein cure 217 examples, effective 254 examples, invalid 0 example, cure rate is 85.4%, obvious effective rate is 100%, and does not find obvious adverse reaction after use.
Detailed description of the invention
Embodiment 1
[prescription] Radix Dipsaci 120g, Caulis Piperis Kadsurae 150g, Caulis Sinomenii 100g, Herba speranskiae tuberculatae 180g, Herba Lycopodii 100g, Flos Carthami 120g, Lignum Sappan 80g and Halitum 50g.
[preparation method] takes described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding according to selected parts by weight and extracts 1 time, add the water of 20 times of drug weight, decoct 3 hours, merge and filter gained extracting solution, it is the clear paste of 1.05 by gained filtrate reduced in volume to 60 DEG C relative density, then stand overnight and filter, add sodium benzoate 2g to gained filtrate and make it dissolve, then add purified water and adjust total amount to 1000ml, stir evenly, embedding, obtains fumigation and washing agent.
Embodiment 2
[prescription] Radix Dipsaci 180g, Caulis Piperis Kadsurae 100g, Caulis Sinomenii 150g, Herba speranskiae tuberculatae 120g, Herba Lycopodii 150g, Flos Carthami 80g, Lignum Sappan 120g and Halitum 10g.
[preparation method] takes described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding according to selected parts by weight and extracts 3 times, add the water of 10 times of drug weight every time, decoct 1 hour every time, merge and filter gained extracting solution, it is the clear paste of 1.10 by gained filtrate reduced in volume to 60 DEG C relative density, then stand overnight and filter, add sodium benzoate 4g to gained filtrate and make it dissolve, then add purified water and adjust total amount to 1000ml, stir evenly, embedding, obtains fumigation and washing agent.
Embodiment 3
[prescription] Radix Dipsaci 150g, Caulis Piperis Kadsurae 120g, Caulis Sinomenii 120g, Herba speranskiae tuberculatae 150g, Herba Lycopodii 120g, Flos Carthami 100g, Lignum Sappan 100g and Halitum 30g.
[preparation method] takes described Radix Dipsaci according to selected parts by weight, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding extract 2 times, first time adds the water of 15 times of drug weight, decoct 1.5 hours, second time adds the water of 10 times of drug weight, decoct 1.5 hours, merge and filter gained extracting solution, it is the clear paste of 1.08 by gained filtrate reduced in volume to 60 DEG C relative density, then stand overnight and filter, add sodium benzoate 3g to gained filtrate and make it dissolve, then add purified water and adjust total amount to 1000ml, stir evenly, embedding, obtain fumigation and washing agent.
Embodiment 4
[prescription] Radix Dipsaci 135g, Caulis Piperis Kadsurae 110g, Caulis Sinomenii 135g, Herba speranskiae tuberculatae 135g, Herba Lycopodii 135g, Flos Carthami 90g, Lignum Sappan 110g and Halitum 20g.
[preparation method] takes described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding according to selected parts by weight and extracts 2 times, first time adds the water of 10 times of drug weight, decoct 1 hour, second time adds the water of 15 times of drug weight, decoct 2 hours, merge and filter gained extracting solution, during by gained filtrate reduced in volume to 60 DEG C, relative density is the clear paste of 1.05, then stand overnight and filter, taking filtrate and add customary adjuvant, conventionally technique makes acceptable spray clinically.
Embodiment 5
[prescription] Radix Dipsaci 165g, Caulis Piperis Kadsurae 135g, Caulis Sinomenii 110g, Herba speranskiae tuberculatae 165g, Herba Lycopodii 110g, Flos Carthami 110g, Lignum Sappan 110g and Halitum 40g.
[preparation method] takes described Radix Dipsaci according to selected parts by weight, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding extract 3 times, first time adds the water of 15 times of drug weight, decoct 1.5 hours, second time adds the water of 10 times of drug weight, decoct 1.5 hours, , third time adds the water of 20 times of drug weight, decoct 1 hour, merge and filter gained extracting solution, it is the clear paste of 1.10 by gained filtrate reduced in volume to 60 DEG C relative density, then stand overnight and filter, take filtrate and add customary adjuvant, conventionally technique makes acceptable liniment clinically.
Embodiment 6
[prescription] Radix Dipsaci 120g, Caulis Piperis Kadsurae 100g, Caulis Sinomenii 100g, Herba speranskiae tuberculatae 120g, Herba Lycopodii 100g, Flos Carthami 80g, Lignum Sappan 80g and Halitum 10g.
[preparation method] takes described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding according to selected parts by weight and extracts 1 time, add the water of 20 times of drug weight, decoct 3 hours, merge and filter gained extracting solution, during by gained filtrate reduced in volume to 60 DEG C, relative density is the clear paste of 1.06, then stands overnight and filters, and then stands overnight and filters, taking filtrate and add customary adjuvant, conventionally technique makes acceptable unguentum clinically.
Embodiment 7
[prescription] Radix Dipsaci 180g, Caulis Piperis Kadsurae 150g, Caulis Sinomenii 150g, Herba speranskiae tuberculatae 180g, Herba Lycopodii 150g, Flos Carthami 120g, Lignum Sappan 120g and Halitum 50g.
[preparation method] takes described Radix Dipsaci according to selected parts by weight, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding extract 2 times, first time adds the water of 20 times of drug weight, decoct 3 hours, second time adds the water of 15 times of drug weight, decoct 1 hour, merge and filter gained extracting solution, during by gained filtrate reduced in volume to 60 DEG C, relative density is the clear paste of 1.10, then stand overnight and filter, add sodium benzoate 3g to gained filtrate and make it dissolve, then stand overnight and filter, take filtrate and add customary adjuvant, conventionally technique makes acceptable paste clinically.
Embodiment 8
[prescription] Radix Dipsaci 170g, Caulis Piperis Kadsurae 140g, Caulis Sinomenii 105g, Herba speranskiae tuberculatae 140g, Herba Lycopodii 115g, Flos Carthami 95g, Lignum Sappan 85g and Halitum 25g.
[preparation method] takes described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding according to selected parts by weight and extracts 3 times, add the water of 15 times of drug weight every time, decoct 2 hours every time, merge and filter gained extracting solution, during by gained filtrate reduced in volume to 60 DEG C, relative density is the clear paste of 1.10, then stand overnight and filter, add sodium benzoate 3g to gained filtrate and make it dissolve, then stand overnight and filter, taking filtrate and add customary adjuvant, conventionally technique makes acceptable patch clinically.
Obviously, above-described embodiment is only for clearly demonstrating example, and is not the restriction to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here without also cannot all of embodiment be given exhaustive.And the apparent change thus extended out or variation are still among the protection domain of the invention.
Claims (10)
1. the pharmaceutical composition being used for treating prolapse of lumbar intervertebral disc, it is characterized in that, the crude drug of described pharmaceutical composition consists of: Radix Dipsaci 120-180 weight portion, Caulis Piperis Kadsurae 100-150 weight portion, Caulis Sinomenii 100-150 weight portion, Herba speranskiae tuberculatae 120-180 weight portion, Herba Lycopodii 100-150 weight portion, Flos Carthami 80-120 weight portion, Lignum Sappan 80-120 weight portion and Halitum 10-50 weight portion.
2. pharmaceutical composition according to claim 1, it is characterized in that, the crude drug of described pharmaceutical composition consists of: Radix Dipsaci 150 weight portion, Caulis Piperis Kadsurae 120 weight portion, Caulis Sinomenii 120 weight portion, Herba speranskiae tuberculatae 150 weight portion, Herba Lycopodii 120 weight portion, Flos Carthami 100 weight portion, Lignum Sappan 100 weight portion and Halitum 30 weight portion.
3. the method preparing pharmaceutical composition as claimed in claim 1 or 2, it is characterised in that comprise the steps:
Take described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding according to selected parts by weight to extract, merge and filter gained extracting solution, by gained filtrate reduced in volume to clear paste, after standing and filtering, taking filtrate and add customary adjuvant, conventionally technique makes acceptable exterior-applied formulation clinically.
4. preparation method according to claim 3, it is characterised in that comprise the steps:
Take described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding according to selected parts by weight to extract 1-3 time, add the water of 10-20 times of drug weight every time, decoct 1-3 hour every time, merge and filter gained extracting solution, during by gained filtrate reduced in volume to 60 DEG C, relative density is the clear paste of 1.05-1.10, after standing and filtering, taking filtrate and add customary adjuvant, conventionally technique makes acceptable spray, liniment, unguentum, paste, lotion, patch or fumigation and washing agent clinically.
5. the preparation method according to claim 3 or 4, it is characterised in that comprise the steps:
Described Radix Dipsaci is taken according to selected parts by weight, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding extract 2 times, first time adds the water of 15 times of drug weight, decoct 1.5 hours, second time adds the water of 10 times of drug weight, decoct 1.5 hours, merge and filter gained extracting solution, during by gained filtrate reduced in volume to 60 DEG C, relative density is the clear paste of 1.08, after standing and filtering, take filtrate and add customary adjuvant, conventionally technique makes acceptable spray clinically, liniment, unguentum, paste, lotion, patch or fumigation and washing agent.
6. the pharmaceutical composition described in claim 1 or 2 adds the clinically-acceptable external preparation that customary adjuvant, conventionally technique are made.
7. the fumigation and washing agent being used for treating prolapse of lumbar intervertebral disc, it is characterised in that pharmaceutical composition described in claim 1 or 2, adding 2-5 parts by weight sodium is adjuvant, and conventionally technique is prepared from.
8. the method preparing fumigation and washing agent described in claim 7, it is characterized in that, the step that described Radix Dipsaci, Caulis Piperis Kadsurae, Caulis Sinomenii, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Lignum Sappan and Halitum mixing and water adding extract is taken including according to selected parts by weight, merge gained extracting solution and filter, by gained filtrate reduced in volume to clear paste, stand and after filtering, add the sodium benzoate of selected parts by weight so as to dissolve, add purified water and adjust volume, to obtain final product.
9. the purposes in the medicine of preparation treatment prolapse of lumbar intervertebral disc of the pharmaceutical composition described in claim 1 or 2.
10. purposes according to claim 9, it is characterised in that described prolapse of lumbar intervertebral disc is prolapse of lumbar intervertebral disc syndrome of static blood blocking collaterals.
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| CN109078092A (en) * | 2018-09-27 | 2018-12-25 | 杨兴贵 | A kind of liquid medicine and preparation method thereof for treating protrusion of lumber intervertebral disc |
| CN111529667A (en) * | 2020-06-11 | 2020-08-14 | 浙江一真堂健康管理有限公司 | Traditional Chinese medicine composition for treating lumbar intervertebral disc protrusion and application |
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| CN102784208A (en) * | 2012-08-08 | 2012-11-21 | 冯安华 | Medicament for treating lumbar disc herniation and preparation method thereof |
| CN103230430A (en) * | 2013-04-07 | 2013-08-07 | 广东恒诚制药有限公司 | Traditional Chinese medicine gel cream for treating lumbar disc herniation |
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| JPH10175872A (en) * | 1996-12-12 | 1998-06-30 | Shinichi Konuma | Solidification of alcohol-extracted balsam extract into powder |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102784208A (en) * | 2012-08-08 | 2012-11-21 | 冯安华 | Medicament for treating lumbar disc herniation and preparation method thereof |
| CN103230430A (en) * | 2013-04-07 | 2013-08-07 | 广东恒诚制药有限公司 | Traditional Chinese medicine gel cream for treating lumbar disc herniation |
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| 中西医结合综合治疗腰椎间盘突出症121 例;尹延亭，等;《河北中医》;20030131;第25卷(第1期);第48-50页 * |
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