CN102784208A - Medicament for treating lumbar disc herniation and preparation method thereof - Google Patents
Medicament for treating lumbar disc herniation and preparation method thereof Download PDFInfo
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- CN102784208A CN102784208A CN2012102802760A CN201210280276A CN102784208A CN 102784208 A CN102784208 A CN 102784208A CN 2012102802760 A CN2012102802760 A CN 2012102802760A CN 201210280276 A CN201210280276 A CN 201210280276A CN 102784208 A CN102784208 A CN 102784208A
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Abstract
The invention provides a medicament for treating lumbar disc herniation and a preparation method thereof. The preparation method comprises the following steps of: adding water into club moss, american lopseed, ligusticum, astragalus, eucommia, red paeony root, safflower, brazilwood, radix linderae, angleworm, hemlock parsley, corydalis tuber, artemisiae anomala, ass-hide glue, radix gentianae macrophyllae, teasel root, heracleum hemsleyanum michaux, radix achyranthis bidentatae, spatholobus stem, acanthopanax bark and the like, and decocting the mixture to obtain decoction; condensing the decoction, and adding common adjuvants; adding purified water until the crude drug content is 1g/ml; and encapsulating and sterilizing to obtain an oral liquid preparation. The medicament is capable of removing blood stasis, relieving spasm and pain and achieving a good lumbar disc herniation treatment effect; by virtue of clinical observation, the efficiency of the medicament is 97%; and the medicament contains no western medicine preparations, has no side effects such as damage to the visceral organs of a human body and does not cause adverse effects after operation.
Description
Technical field
The present invention relates to a kind of medicine of treating prolapse of lumbar intervertebral disc, particularly a kind of is the Chinese medicine of the treatment prolapse of lumbar intervertebral disc of crude drug preparation with Chinese medicine.The invention still further relates to the method for preparing of this medicine.
Background technology
Prolapse of lumbar intervertebral disc is because the lumbar intervertebral disc degeneration; Fibrous ring is broken, and the outstanding stimulation of vertebral pulp or a series of clinical symptoms and sign that pressuring neural root, cauda equina nerve showed are commonly called as in " waist dash forward disease "; Be clinical commonly encountered diseases and cause the lumbago and skelalgia most important reason; Normal patient's the live and work of giving brings many miseries, even causes deformity, disability.Prolapse of lumbar intervertebral disc is one of clinical the most illness of seeing of orthopaedics more, be current frequently-occurring disease, and the rehabilitation difficulty is bigger.
At present, the treatment of prolapse of lumbar intervertebral disc mainly contains two kinds of operative treatment and non-operative treatments.Non-operative treatment is the basic therapy of treatment prolapse of lumbar intervertebral disc, and about patient more than 80% all can be eased and fully recover through expectant treatment.Operative treatment is a kind of very sophisticated operation, has passed through hundreds of thousands example, routine patients' up to a million check.But any operation all has certain risk, and the prominent disease operation of waist is no exception.The operation related complication has intraoperative hemorrhage, blood vessel injury, spinal dura mater damage, cauda equina injury, nerve root damage etc.Shock, dark venous thrombosis, dyspnea, pulmonary infection and pulmonary atelectasis, urinary tract infection, whole body complication such as abdominal distention vomiting might appear in operation back peri-operation period.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine of treating prolapse of lumbar intervertebral disc, natural pure, the safety non-toxic of this medicine does not have dependency, is free from side effects.
The method for preparing that this medicine is provided in addition is an another object of the present invention.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Herba Lycopodii 30-40 Herba speranskiae tuberculatae 30-40 Radix Angelicae Sinensis 25-35
Radix Astragali 25-35 Cortex Eucommiae 25-35 Radix Paeoniae Rubra 20-30
Flos Carthami 20-30 Lignum Sappan 25-35 Radix Linderae 20-30
Lumbricus 20-30 Rhizoma Chuanxiong 20-30 Rhizoma Corydalis 20-30
Herba Artemisiae Anomalae 15-25 Colla Corii Asini 25-35 Radix Gentianae Macrophyllae 20-30
Radix Dipsaci 20-30 Radix Angelicae Pubescentis 15-25 Radix Achyranthis Bidentatae 25-35
Caulis Spatholobi 25-35 Cortex Acanthopancis 15-25.
Can said medicine be processed on the pharmaceutics any dosage form such as tablet, pill, powder, capsule, the present invention is oral liquid preferably.
The concrete method for preparing of above-mentioned each component being processed oral liquid according to the invention is:
Above-mentioned medicaments in part by weight is cleaned up the back mix homogeneously, add two times of weight parts waters, decoct each 20 minutes 2～4 times; Collecting decoction filters, and filtrating is condensed into the clear paste of 70 ℃ of relative densities 1.15～1.18; Cold preservation is left standstill, and gets supernatant and filters, and adds conventional adjuvant in the filtrating; Mixing, adding purified water is 1g/ml to containing the crude drug amount, oral liquid formulations is processed in embedding, sterilization.
Method for using: oral, each 1 bag, every bag of 500ml, every day three times.
The traditional Chinese medical science is thought: prolapse of lumbar intervertebral disc belongs to the category of " lumbago and skelalgia ", " waist numbness ".The cause of disease of lumbago and skelalgia is a deficiency of both the liver and kidney, and insufficiency of vital energy and blood, exopathogenic factor are the tumbling down sprain and contusion, obstruction of collaterals by blood stasis, and QI and blood is obstructed, stagnation of QI and blood may bring about pain.We are with the tonifying liver QI invigorating, and the collateral dredging promoting the circulation of blood is main, and the hot temperature of Herba Lycopodii bitter in the mouth is gone into liver spleen kidney three warps in the side, expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons to promote blood circulation; The hot temperature of Herba speranskiae tuberculatae sweet in the mouth, expelling wind and removing dampness, Soothe tendons and activating-blood anodyne; The Radix Angelicae Sinensis sweet-bitter flavor is gone into the conscience spleen channel, benefiting blood and regulating blood circulation, menstruction regulating and pain relieving; Radix Astragali sweet in the mouth tepor is gone into the lung spleen, and benefit is defended consolidating superficial resistance, helps vaporous muscles and bones; The little hot temperature of Cortex Eucommiae sweet in the mouth is gone into the Liver and kidney warp, tonifying liver and kidney and strengthening bones and muscles; The Radix Paeoniae Rubra sour in the mouth is bitter cool, goes into the liver spleen channel, clots absorbing pain relieving, removing heat from blood detumescence; Flos Carthami acrid in the mouth temperature is gone into conscience, promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving; The Lignum Sappan sweet-salty is flat, goes into conscience, promoting the circulation of blood removing blood stasis with potent drugs, reducing swelling and alleviating pain; Radix Linderae acrid in the mouth temperature is gone into spleen lung kidney urinary bladder channel, the pleasant breast of opening, dispersing cold for relieving pain; Earthworm smell is salty-cold, goes into liver spleen lung, heat clearing away suppressing the hyperactive liver, Zhichuan collateral dredging; Rhizoma Chuanxiong acrid in the mouth temperature is gone into the liver and gall warp, activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, promoting blood circulation to relieve pain; The flat bitter temperature of Rhizoma Corydalis flavor is gone into liver stomach warp, promoting blood circulation to remove blood stasis, and regulating QI to relieve pain removes wind; The Herba Artemisiae Anomalae sweet-bitter flavor is gone into heart spleen channel, and removing blood stasis stimulates the menstrual flow, healing up sore and subduing swelling; The Colla Corii Asini sweet in the mouth is put down into lung Liver and kidney warp, nourishing YIN and supplementing blood, main hard muscles and bones; The Radix Gentianae Macrophyllae acrid in the mouth is flat, goes into liver stomach gallbladder meridian, expelling wind and removing dampness and blood Shujin, clearing away heat and promoting diuresis; The hot tepor of Radix Dipsaci bitter in the mouth is gone into the Liver and kidney warp, invigorating the liver and kidney reuniting the fractured tendons and bones, blood circulation regulating, aching pain in waist and back; The bitter temperature of Radix Angelicae Pubescentis acrid in the mouth is gone into the kidney bladder, expelling wind and dampness, dispersing cold for relieving pain, anemofrigid-damp arthralgia; Radix Achyranthis Bidentatae sweet in the mouth picric acid is flat, goes into the Liver and kidney warp, invigorating the liver and kidney, bone and muscle strengthening; Caulis Spatholobi bitter but sweet flavor temperature is gone into heart spleen, relaxing muscles and tendons to promote blood circulation, soreness of waist and knee joint, fluent passages through which vital energy circulates; Cortex Acanthopancis acrid in the mouth temperature is gone into the Liver and kidney warp, wind-damp dispelling, shape muscles and bones, activating blood circulation and dissipating phlegm.
More than all medicines share, can the tonifying liver QI invigorating, the collateral dredging promoting the circulation of blood, being used to treat prolapse of lumbar intervertebral disc has good curative effect.No Western medicine prepn does not have the anxiety that harmful effect is arranged after performing the operation to side effect such as human internal organ infringements yet.
For further investigating the clinical efficacy and the safety of medicine of the present invention, select 263 routine prolapse of lumbar intervertebral disc patients that the curative effect of medicine of the present invention is carried out clinical observation.
Criterion of therapeutical effect: according to " the clinical research guideline of new Chinese medicine treatment prolapse of lumbar intervertebral disc " regulation, efficacy determination is main with transference cure, and with reference to change situation such as signs, is divided into healing, produce effects, effective, invalid level Four.Cure: symptom and sign all disappear.Produce effects: symptom and sign are obviously improved.Effectively: symptom and sign have certain improvement.Invalid: symptom and sign all do not have improvement.
Observe 263 routine patients, male 161 examples, women 102 examples, effective 257 examples, invalid 6 examples through treatment.Total effective rate 97%.Have no side effect and untoward reaction.
The specific embodiment
Embodiment: get Herba Lycopodii 30kg, Herba speranskiae tuberculatae 30kg, Radix Angelicae Sinensis 25kg, Radix Astragali 25kg, Cortex Eucommiae 20kg, Radix Paeoniae Rubra 15kg, Flos Carthami 15kg, Lignum Sappan 25kg, Radix Linderae 20kg, Lumbricus 20kg, Rhizoma Chuanxiong 20kg, Rhizoma Corydalis 20kg, Herba Artemisiae Anomalae 20kg, Colla Corii Asini 20kg, Radix Gentianae Macrophyllae 20kg, Radix Dipsaci 20kg, Radix Angelicae Pubescentis 16kg, Radix Achyranthis Bidentatae 20kg, Caulis Spatholobi 25kg, Cortex Acanthopancis 20kg, clean, add two times of weight parts waters and decoct 3 times with clear water; Each 20 minutes; Collecting decoction filters, and filtrating is condensed into the clear paste of 70 ℃ of relative densities 1.15～1.18; Cold preservation is left standstill; Get supernatant and filter, add conventional adjuvant, mixing in the filtrating; Adding purified water is 1g/ml to containing the crude drug amount, and oral liquid formulations is processed in embedding, sterilization.
The present invention has:
1, lack medicine time, curative effect is long, and is reliable for effect.
2, take Chinese medicine, clothes are fried in shallow oil certainly certainly, and are very convenient.
3, spend to lack, curative effect is high, and the common people can accept.
Following for a kind of effect observation of the Drug therapy patient who treats prolapse of lumbar intervertebral disc 263 examples below:
Claims (3)
1. medicine of treating prolapse of lumbar intervertebral disc is characterized in that:
Medicine according to the invention is that feedstock production obtains by following parts by weight of traditional Chinese medicines:
Herba Lycopodii 30-40 Herba speranskiae tuberculatae 30-40 Radix Angelicae Sinensis 25-35
Radix Astragali 25-35 Cortex Eucommiae 25-35 Radix Paeoniae Rubra 20-30
Flos Carthami 20-30 Lignum Sappan 25-35 Radix Linderae 20-30
Lumbricus 20-30 Rhizoma Chuanxiong 20-30 Rhizoma Corydalis 20-30
Herba Artemisiae Anomalae 15-25 Colla Corii Asini 25-35 Radix Gentianae Macrophyllae 20-30
Radix Dipsaci 20-30 Radix Angelicae Pubescentis 15-25 Radix Achyranthis Bidentatae 25-35
Caulis Spatholobi 25-35 Cortex Acanthopancis 15-25.
2. the medicine of prolapse of lumbar intervertebral disc according to claim 1, its characteristic is being that described medicine is processed oral liquid.
3. the method for preparing of the medicine of the described treatment prolapse of lumbar intervertebral disc of claim 2 is: above-mentioned medicaments in part by weight is cleaned up the back mix homogeneously, add two times of weight parts waters, decoct each 20 minutes 2～4 times; Collecting decoction filters, and filtrating is condensed into the clear paste of 70 ℃ of relative densities 1.15～1.18; Cold preservation is left standstill, and gets supernatant and filters, and adds conventional adjuvant in the filtrating; Mixing, adding purified water is 1g/ml to containing the crude drug amount, oral liquid formulations is processed in embedding, sterilization.
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| CN201210280276.0A CN102784208B (en) | 2012-08-08 | 2012-08-08 | Medicament for treating lumbar disc herniation and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463241A (en) * | 2013-08-26 | 2013-12-25 | 荣成市科学技术情报研究所 | Traditional Chinese medicine composition for treating lumbar disc herniation |
| CN104127508A (en) * | 2014-08-14 | 2014-11-05 | 北京市大兴区红星医院 | Medicine composition for treating protrusion of lumbar intervertebral disc and preparation method thereof |
| CN104784596A (en) * | 2015-03-31 | 2015-07-22 | 济南正骐生物科技有限公司 | Traditional Chinese medicine for treating ankylosing spondylitis |
| CN105535902A (en) * | 2016-01-18 | 2016-05-04 | 杨发祥 | Externally dressed ointment for treating intervertebral disc herniation |
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| CN1814247A (en) * | 2005-11-22 | 2006-08-09 | 田茂宁 | Chinese medicine bone-setting ointment and preparing method |
| CN1895642A (en) * | 2005-07-12 | 2007-01-17 | 侯保君 | Traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain and preparation method thereof |
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2012
- 2012-08-08 CN CN201210280276.0A patent/CN102784208B/en not_active Expired - Fee Related
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| CN1895642A (en) * | 2005-07-12 | 2007-01-17 | 侯保君 | Traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain and preparation method thereof |
| CN1814247A (en) * | 2005-11-22 | 2006-08-09 | 田茂宁 | Chinese medicine bone-setting ointment and preparing method |
Non-Patent Citations (3)
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| 何元诚等: "退变性腰椎管狭窄症的中医药治疗进展", 《广西中医学院学报》, vol. 10, no. 04, 31 December 2007 (2007-12-31) * |
| 杨秀惠等: "中药治疗膝关节骨性关节炎概述", 《实用中医药杂志》, vol. 25, no. 01, 31 January 2009 (2009-01-31) * |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463241A (en) * | 2013-08-26 | 2013-12-25 | 荣成市科学技术情报研究所 | Traditional Chinese medicine composition for treating lumbar disc herniation |
| CN104127508A (en) * | 2014-08-14 | 2014-11-05 | 北京市大兴区红星医院 | Medicine composition for treating protrusion of lumbar intervertebral disc and preparation method thereof |
| CN104127508B (en) * | 2014-08-14 | 2016-06-29 | 北京市大兴区红星医院 | For treating pharmaceutical composition and the preparation method of prolapse of lumbar intervertebral disc |
| CN104784596A (en) * | 2015-03-31 | 2015-07-22 | 济南正骐生物科技有限公司 | Traditional Chinese medicine for treating ankylosing spondylitis |
| CN105535902A (en) * | 2016-01-18 | 2016-05-04 | 杨发祥 | Externally dressed ointment for treating intervertebral disc herniation |
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| CN102784208B (en) | 2014-02-12 |
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