CN104116825B - Improve Chinese medicine composition of menopausal women sleep quality and preparation method thereof - Google Patents
Improve Chinese medicine composition of menopausal women sleep quality and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine decoction improving menopausal women sleep quality, be prepared from by the primary raw material of following weight proportioning: Semen Cuscutae 8-12 part, Rhizoma Chuanxiong 5-12 part, Concha Ostreae (calcined) 12-18 part, Radix Paeoniae Alba 8-16 part, Herba Epimedii 8-16 part, Ramulus Uncariae Cum Uncis 8-16 part, Herba Leonuri 6-12 part, Radix Scutellariae 6-12 part, Semen Ziziphi Spinosae (parched) 4-9 part, Ramulus Cinnamomi 3-9 part, Radix Glycyrrhizae 3-9 part, Cortex Phellodendri 4-9 part, Fructus Schisandrae Chinensis 3-9 part, Herba Lycopi 3-8 part, Radix Saposhnikoviae 2-5 part, Radix Angelicae Dahuricae 4-9 part.Chinese medicine decoction of the present invention has good effect to the sleep quality improving menopausal women, has effect of mind tranquilizing and the heart calming, relieving restlessness resolving depression, hypnotic, evident in efficacy and without any side effects.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to and a kind ofly improve Chinese medicine composition of menopausal women sleep quality and preparation method thereof.
Background technology
Refer to that woman month menopause is only not all right menopause.In actual life, have many people to think, climacteric is exactly menopause, and this is diverse two medical concept of implication in fact.Climacteric refers to the transformation period of women from hypogonadism to completely losing; Menopause then only refers to that moon menopause is only not all right.The stage that ovary progressively fails has been there is before menopause, according to investigations, about 2 ~ 4 years, different in size different people, be called premenopause.After menopause, ovarian function is more low, but not necessarily disappears completely immediately, generally also will experience 2 ~ 3 years, also has and reaches 6 ~ 8 years, even longer.So climacteric is the summation of premenopause, menopause and postmenopause.
Women, after menopause, body & mind there will be a series of malaise symptoms, particularly can have a strong impact on the sleep quality of women.The main manifestations of climacteric syndrome has: Spirit nerve symptoms of disease: excited type, and emotion is irritated, emotional, insomnia, absent minded, multi-lingual, cry and scream loudly; Depressive type, agitation, anxiety, trouble in mind, hypomnesis, be slow in action, depressed etc.; Vasomotor symptoms, flushing hectic fever is the characteristic symptom after women enters climacteric, sustainable 1 year of this symptom of the patient of 82%; Cardiovascular symptom, 28.9% patient has pseudoangina, sometimes with cardiopalmus, uncomfortable in chest etc., symptom occurs often to affect by Nervous and Mental Factors, in addition, about have 15.2% patient to occur mild hypertension, its feature is that systolic pressure raises, diastolic pressure is not high, paroxysmal is shown effect, and occurs dizzy, headache, uncomfortable in chest, nervous when blood pressure raises; Skin tension declines, dry, thinning etc.It should be noted that, the sleep quality of women can be had a strong impact on menopause, main manifestations be following some: 1, early awakening: for a long time wake up in advance than usual, can not again fall asleep after the latter wakes up after midnight, and second day mental status is very poor, daytime can be sleepy, tired, and chronic insomnia also can cause the situations such as dizziness, cardiopalmus, absent minded, hypomnesis.Whether 2, difficulty falling asleep: time for falling asleep extends, and tosses about, no matter have thing interference all habitually to can't fall asleep, and very tiredly very tiredly also cannot to fall asleep fast.3, Depth of sleep is not enough: night easily wakes up with a start, and sleeps not steady and sure, has obviously had a rest a whole night, but as not sleeping, dizzy tired out, even listless.4, dreaminess, has nightmares: everyone can have a dream evening, if but get up to remember do-it-yourself a lot of dream morning, or often waken up with a start by bad dream, will sleep quality be had a strong impact on.
The malaise symptoms in menopause can have a strong impact on the physical and mental health of women, therefore in menopause, women should note following some: 1. wear which floor clothes, the inside is cotton products preferably more.If there is hectic fever, just take off the clothes of outside.In addition, when hectic fever starts, have a drink cold water or cold fruit juice.2. wear cotton nightwear processed, keep bedroom to cool off oneself.Many which floor sheets of pad on bed.Sheet above drenching when there is hectic fever, can take away sheet above.3. be careful in one's diet, do not drink, also do not eat maror.4. take regular exercise.Some women finds to take regular exercise to alleviate the impact of hectic fever, and can help for sleep.5. take liberties with joke more.In bean or pea containing a kind of be the material of same genus with estrogen, perhaps can help to alleviate the symptoms such as hectic fever.Also cool bean milk etc. can be drunk when hectic fever starts.
Application publication number is CN101934007A(application number 201010278949.X) Chinese patent literature disclose a kind of by name " the syndromic Chinese herbal medicine for the treatment of menopausal women ", this Chinese herbal medicine is by Rhizoma Curculiginis 25-35 part; Herba Epimedii 25-35 part; Radix Morindae Officinalis 20-30 part; Radix Angelicae Sinensis 25-35 part; Stir-baked CORTEX PHELLODENDRI with salt solution 15-25 part; Radix Rehmanniae 20-30 part; Carapax et Plastrum Testudinis 25-30 part; Caulis Polygoni Multiflori 15-25 part; Cortex Albiziae 15-25 part; Semen Astragali Complanati 10-20 part; Ramulus Euonymi 10-20 part; Semen Euphorbiae 5-15 part forms.Application publication number is CN103330915A(application number 201310276188.8) Chinese patent literature disclose a kind of by name " a kind of Chinese medicine composition for the treatment of perimenopausal syndrome ", it is made up of according to certain weight proportion Radix Bupleuri (processed with vinegar), Radix Curcumae, Rhizoma Corydalis, Fructus Toosendan, Cortex Lycii, Herba Artemisiae Annuae, Carapax Trionycis, Radix Scrophulariae, Fructus Tritici Levis, Radix Rehmanniae, Caulis Polygoni Multiflori, stir-fry Fructus Gardeniae, Flos Carthami, Fructus Akebiae, the Rhizoma Anemarrhenae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Glycyrrhizae.
In a word, Chinese medicine achieves certain curative effect in treatment climacteric syndrome etc., but also there are some problems: not yet have at present and develop special medicine for improving menopausal women sleep quality, and active drug is unsatisfactory to the therapeutic effect improving menopausal women sleep quality, need raising further perfect.
Summary of the invention
In order to make up the deficiency of above-mentioned technology, the object of the present invention is to provide and a kind ofly improve Chinese medicine decoction of menopausal women sleep therapy and preparation method thereof, there is effect of dispersing the stagnated live-QI to relieve the stagnation of QI, improving water flood quality, can effectively make up above-mentioned deficiency.
Technical scheme of the present invention is:
Improve the Chinese medicine decoction of menopausal women sleep quality, take off the primary raw material stating weight proportion and be prepared from: Semen Cuscutae 8-12 part, Rhizoma Chuanxiong 5-12 part, Concha Ostreae (calcined) 12-18 part, Radix Paeoniae Alba 8-16 part, Herba Epimedii 8-16 part, Ramulus Uncariae Cum Uncis 8-16 part, Herba Leonuri 6-12 part, Radix Scutellariae 6-12 part, Semen Ziziphi Spinosae (parched) 4-9 part, Ramulus Cinnamomi 3-9 part, Radix Glycyrrhizae 3-9 part, Cortex Phellodendri 4-9 part, Fructus Schisandrae Chinensis 3-9 part, Herba Lycopi 3-8 part, Radix Saposhnikoviae 2-5 part, Radix Angelicae Dahuricae 4-9 part.
Improve the Chinese medicine decoction of menopausal women sleep quality, take off the primary raw material stating weight proportion and be prepared from: Semen Cuscutae 9-11 part, Rhizoma Chuanxiong 7-10 part, Concha Ostreae (calcined) 14-16 part, Radix Paeoniae Alba 10-14 part, Herba Epimedii 10-14 part, Ramulus Uncariae Cum Uncis 10-14 part, Herba Leonuri 8-10 part, Radix Scutellariae 8-10 part, Semen Ziziphi Spinosae (parched) 5-7 part, Ramulus Cinnamomi 4-8 part, Radix Glycyrrhizae 5-7 part, Cortex Phellodendri 4-8 part, Fructus Schisandrae Chinensis 5-7 part, Herba Lycopi 4-6 part, Radix Saposhnikoviae 3-4 part, Radix Angelicae Dahuricae 6-8 part.
Improve the Chinese medicine decoction of menopausal women sleep quality, take off the primary raw material stating weight proportion and be prepared from: Semen Cuscutae 10 parts, Rhizoma Chuanxiong 9 parts, Concha Ostreae (calcined) 15 parts, the Radix Paeoniae Alba 12 parts, Herba Epimedii 12 parts, Ramulus Uncariae Cum Uncis 12 parts, Herba Leonuri 9 parts, Radix Scutellariae 9 parts, Semen Ziziphi Spinosae (parched) 6 parts, Ramulus Cinnamomi 6 parts, 6 parts, Radix Glycyrrhizae, Cortex Phellodendri 6 parts, Fructus Schisandrae Chinensis 6 parts, Herba Lycopi 5 parts, Radix Saposhnikoviae 3.5 parts, the Radix Angelicae Dahuricae 7 parts.
The preparation method of above-mentioned Chinese medicine decoction, step is as follows:
(1) Semen Cuscutae, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are soaked 1-3 hour, water consumption is 1-5 times of crude drug gross weight;
(2) Semen Cuscutae after immersion, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are decocted with water 40-80 minute, water consumption is 1-4 times of crude drug gross weight, filters to get filtrate and medicinal residues;
(3) step (2) gained medicinal residues are decocted with water 20-60 minute again, filter to get filtrate;
(4) by step (2) and the mixing of step (3) gained filtrate, sterile packaged, obtains Chinese medicine decoction.
The preparation method of above-mentioned Chinese medicine decoction, preferred scheme is, step (1) is soaked 1.5-2.5 hour (preferably 2 hours).
The preparation method of above-mentioned Chinese medicine decoction, preferred scheme is, step (1) water consumption is 2-4 times (preferably 3 times) of crude drug gross weight.
The preparation method of above-mentioned Chinese medicine decoction, preferred scheme is, step (2) decocts with water 50-70 minute (preferably 60 minutes).
The preparation method of above-mentioned Chinese medicine decoction, preferred scheme is, step (2) water consumption is 2-3 times (preferably 2.5 times) of crude drug gross weight.
The preparation method of above-mentioned Chinese medicine decoction, preferred scheme is, step (2) gained medicinal residues are decocted with water 30-50 minute (preferably 40 minutes) by step (3) again.
Present invention also offers the application of described Chinese medicine decoction when the medicine of preparation treatment menopausal women poor sleeping quality, difficulty falling asleep.
Using method: for making Chinese medicine composition of the present invention reach optimum therapeuticing effect, the Chinese medicine composition made, every day, potion, took in the morning and evening, 7 days courses for the treatment of for 1 hour after meal.
The pharmacological effect of each crude drug is respectively:
Semen Cuscutae: base is former: be the dry mature seed of convolvulus cuscuta plant.Nature and flavor: sweet, temperature.Gui Jing: return liver,kidney,spleen warp.Effect: nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.Cure mainly: for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.
Rhizoma Chuanxiong: base is former: be the dry rhizome of samphire Rhizoma Chuanxiong.Nature and flavor: pungent, temperature.Gui Jing: return liver, gallbladder, pericardium channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.Curing mainly: for menoxenia. amenorrhea dysmenorrhea, mass in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache.Rheumatic arthralgia.
Concha Ostreae (calcined): nature and flavor: bitter in the mouth.Effect: restrain astringent or styptic treatment for spontaneous sweating, relieving gastric hyperacidity to alleviate stomachache, tranquillization with heavy prescription, hard masses softening and resolving.Cure mainly: all cards of slippage (spontaneous perspiration, night sweat, frequent micturition, leukorrhagia, metrorrhagia, seminal emission etc.), stomachache pantothenic acid, irritability, insomnia, excessive rising of liver-YANG, has a dizzy spell.There is the effect strengthening arresting sweating and strengthening superficial resistance.Concha Ostreae (calcined) can with the Radix Astragali, Radix Ephedrae, Fructus Tritici Levis is compatible.With Radix Saposhnikoviae, the Rhizoma Atractylodis Macrocephalae is compatible stopping perspiration with astringents, effect of dispelling wind to relieve the exterior syndrome.
The Radix Paeoniae Alba: base is former: this product is the dry root of ranunculaceae plant Radix Paeoniae.Nature and flavor: bitter, sour, are slightly cold.Gui Jing: return liver, spleen channel.Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Cure mainly: dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Herba Epimedii: another name: Epimedium, Herba Epimedii, Birdfoot, trident wind, epilepsy, Herba Epimedii.Nature and flavor, acrid in the mouth, hardship, temperature.Gui Jing: return liver, kidney channel.Effect: kidney invigorating and YANG supporting, expelling wind and removing dampness.Cure mainly: sexual impotence erectile problem, hemiplegia is unsuccessful, dribbling urination, and muscles and bones contraction is anxious, and cough, optic atrohic blindness after being ill, toothache caused by fire of deficiency type, hemiplegia, weakness of the waist and knees, rheumatic arthralgia, extremity are meciless.
Ramulus Uncariae Cum Uncis: base is former: be the dry stem and branch with belt hook of Maguireothamnus speciosus Ramulus Uncariae Cum Uncis, Ramulus Uncariae macrophyllae, Ramulus Uncariae Cum Uncis, Uncaria sinensis (Oliv.) Havil. or stockless fruit Ramulus Uncariae Cum Uncis.Nature and flavor: sweet are cool.Gui Jing: return liver, pericardium channel.Effect: heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.Cure mainly: dizzy for having a headache. dysphoric cold, infantile convulsion is twitched, pre-eclampsia; Hypertension.
Herba Leonuri: base is former: be the fresh of labiate Herba Leonuri or dry aerial parts.Nature and flavor: bitter, pungent, are slightly cold.Gui Jing: return liver, pericardium channel.Effect: promoting blood flow to regulate menstruation, inducing diuresis to remove edema.Cure mainly: for menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.
Radix Scutellariae: base is former: be the dry root of labiate Radix Scutellariae.Nature and flavor: bitter, cold.Gui Jing: return lung, gallbladder, spleen, large intestine, small intestine meridian.Effect: heat clearing and damp drying, rushes down people's removing toxic substances, hemostasis, antiabortive.Cure mainly: for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Semen Ziziphi Spinosae (parched): base is former: be the seed of Rhamnaceae plant Ziziphi Spinosae.Nature and flavor: sweet in the mouth, property is put down.Gui Jing: GUIXIN, spleen, liver, gallbladder meridian.Effect: nourishing the liver, mind calming, calms the nerves, arresting sweating.Cure mainly: control restlessness of asrhenia type and insomnia, palpitate with fear seized with terror swollen, excessive thirst, deficiency and coldness.
Ramulus Cinnamomi: base is former: be the dry twig of canella Cortex Cinnamomi.Nature and flavor: acrid, sweet, warm.Gui Jing: GUIXIN, lung, urinary bladder channel.Effect: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Cure mainly: for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Radix Glycyrrhizae: base is former: be drying report and the rhizome of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..Nature and flavor: sweet are flat.Gui Jing: GUIXIN.Lung, spleen, stomach warp.Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Cure mainly: for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of institute's abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Cortex Phellodendri: base is former: be the dry bark of rutaceae wampee.Nature and flavor: bitter, cold.Gui Jing: return kidney, urinary bladder channel.Effect: heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment.Cure mainly: for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi ， flaccidity of feet with lamenness, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Fructus Schisandrae Chinensis: base is former: be the dry mature fruit of magnoliaceae schisandra, practises and claims " Radix Schisandrae Bicoloris ".Nature and flavor: sour, sweet, temperature.Gui Jing: return lung, the heart, kidney channel.Effect: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Cure mainly: for chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Herba Lycopi: base is former: be the dry aerial parts of labiate hair leaf lycopus lucidus.Nature and flavor: bitter, pungent, tepor.Gui Jing: return liver, spleen channel.Effect: blood circulation promoting and blood stasis dispelling, line water detumescence.Cure mainly: for menoxenia, amenorrhea, dysmenorrhea, postnatal blood stasis is suffered from abdominal pain, edema.
Radix Saposhnikoviae: base is former: be the dry root of umbelliferae Saposhnikovia divaricata.Nature and flavor: pungent, sweet. temperature.Gui Jing: return bladder, liver, spleen channel.Effect: inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.Cure mainly: for headache due to common cold. rheumatic arthralgia, rubella pruritus, tetanus.
The Radix Angelicae Dahuricae: base is former: this product is the dry root of the samphire Radix Angelicae Dahuricae or Radix angelicae dahuricae.Nature and flavor: pungent, temperature.Gui Jing: return stomach, large intestine, lung meridian.Effect: loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.Cure mainly: for headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Chinese medicine decoction of the present invention has good effect to the sleep quality improving menopausal women, has effect of mind tranquilizing and the heart calming, relieving restlessness resolving depression, hypnotic, evident in efficacy and without any side effects.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1improve the Chinese medicine decoction of menopausal women sleep quality, be prepared from (getting 5g for every part) by following main materials medicine: Semen Cuscutae 8 parts, Rhizoma Chuanxiong 5 parts, Concha Ostreae (calcined) 12 parts, the Radix Paeoniae Alba 8 parts, Herba Epimedii 8 parts, Ramulus Uncariae Cum Uncis 8 parts, Herba Leonuri 6 parts, Radix Scutellariae 6 parts, Semen Ziziphi Spinosae (parched) 4 parts, Ramulus Cinnamomi 3 parts, 3 parts, Radix Glycyrrhizae, Cortex Phellodendri 4 parts, Fructus Schisandrae Chinensis 3 parts, Herba Lycopi 3 parts, Radix Saposhnikoviae 2 parts, the Radix Angelicae Dahuricae 4 parts.
The preparation method of above-mentioned Chinese medicine decoction, preparation process is as follows:
(1) Semen Cuscutae, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are soaked 1 hour, water consumption is 1 times of crude drug gross weight;
(2) Semen Cuscutae after immersion, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are decocted with water 40 minutes, water consumption is 1 times of crude drug gross weight, filters to get filtrate and medicinal residues;
(3) step (2) gained medicinal residues are decocted with water 20 minutes again, filter to get filtrate;
(4) by step (2) and the mixing of step (3) gained filtrate, sterile packaged, obtains Chinese medicine decoction.
model case one: old XX, female, 51 years old.Patient's readme menopause the year before, post menopausal sleep quality is always very poor, fall asleep evening difficult especially, toss about and can't fall asleep always, through often waking up with a start without reason after sleeping, just be difficult to afterwards again fall asleep, daytime, the mental status was very poor, have impact on normal life, thought it is neurasthenia, eat some and treat neurasthenic medicine, invalid.Use the present embodiment gained Chinese medicine decoction, adopt potion every day, in sooner or later within 1 hour after meal, taking, 7 days courses for the treatment of.Take 14 days, patient sleeps's quality makes moderate progress; Take 1 month, patient falls asleep is very fast, and wake up with a start number of times and reduce, malaise symptoms is obviously alleviated; Continue use 2 months, patient's self-induction is fully recovered.
embodiment 2improve the Chinese medicine decoction of menopausal women sleep quality, be prepared from (getting 10g for every part) by following main materials medicine: Semen Cuscutae 12 parts, Rhizoma Chuanxiong 12 parts, Concha Ostreae (calcined) 18 parts, the Radix Paeoniae Alba 16 parts, Herba Epimedii 16 parts, Ramulus Uncariae Cum Uncis 16 parts, Herba Leonuri 12 parts, Radix Scutellariae 12 parts, Semen Ziziphi Spinosae (parched) 9 parts, Ramulus Cinnamomi 9 parts, 9 parts, Radix Glycyrrhizae, Cortex Phellodendri 9 parts, Fructus Schisandrae Chinensis 9 parts, Herba Lycopi 8 parts, Radix Saposhnikoviae 5 parts, the Radix Angelicae Dahuricae 9 parts.
The preparation method of above-mentioned Chinese medicine decoction, preparation process is as follows:
(1) Semen Cuscutae, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are soaked 3 hours, water consumption is 5 times of crude drug gross weight;
(2) Semen Cuscutae after immersion, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are decocted with water 80 minutes, water consumption is 4 times of crude drug gross weight, filters to get filtrate and medicinal residues;
(3) step (2) gained medicinal residues are decocted with water 60 minutes again, filter to get filtrate;
(4) by step (2) and the mixing of step (3) gained filtrate, sterile packaged, obtains Chinese medicine decoction.
embodiment 3improve the Chinese medicine decoction of menopausal women sleep quality, be prepared from (getting 15g for every part) by following main materials medicine: Semen Cuscutae 9 parts, Rhizoma Chuanxiong 7 parts, Concha Ostreae (calcined) 14 parts, the Radix Paeoniae Alba 10 parts, Herba Epimedii 10 parts, Ramulus Uncariae Cum Uncis 10 parts, Herba Leonuri 8 parts, Radix Scutellariae 8 parts, Semen Ziziphi Spinosae (parched) 5 parts, Ramulus Cinnamomi 4 parts, 5 parts, Radix Glycyrrhizae, Cortex Phellodendri 4 parts, Fructus Schisandrae Chinensis 5 parts, Herba Lycopi 4 parts, Radix Saposhnikoviae 3 parts, the Radix Angelicae Dahuricae 6 parts.
The preparation method of above-mentioned Chinese medicine decoction, preparation process is as follows:
(1) Semen Cuscutae, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are soaked 1.5 hours, water consumption is 2 times of crude drug gross weight;
(2) Semen Cuscutae after immersion, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are decocted with water 50 minutes, water consumption is 2 times of crude drug gross weight, filters to get filtrate and medicinal residues;
(3) step (2) gained medicinal residues are decocted with water 30 minutes again, filter to get filtrate;
(4) by step (2) and the mixing of step (3) gained filtrate, sterile packaged, obtains Chinese medicine decoction.
model case two: Lee XX, female, 52 years old.Patient menopause more than a year, in the time that hoc anno is many, patient sleeps's quality extreme difference, evening difficulty falling asleep, after sleeping panesthesia with wake the same, often have horrible nightmares, that wakes up morning is also early special, is difficult to fall asleep after having waken up again, it is obviously a whole night of having had a rest, but daytime is downhearted, dizzy dazed, be unable to pull oneself together.Take the present embodiment 3 gained Chinese medicine decoction, adopt potion every day, in sooner or later within 1 hour after meal, taking, 7 days courses for the treatment of.Take 7 days, patient's malaise symptoms is alleviated to some extent; Use 2 months, patient's malaise symptoms is obviously alleviated, and sleep quality improves comparatively before; Continue use 1 month, patient sleeps is normal, and any discomfort symptom does not appear in the trial employment period.
embodiment 4improve the Chinese medicine decoction of menopausal women sleep quality, be prepared from (getting 20g for every part) by following main materials medicine: Semen Cuscutae 11 parts, Rhizoma Chuanxiong 10 parts, Concha Ostreae (calcined) 16 parts, the Radix Paeoniae Alba 14 parts, Herba Epimedii 14 parts, Ramulus Uncariae Cum Uncis 14 parts, Herba Leonuri 10 parts, Radix Scutellariae 10 parts, Semen Ziziphi Spinosae (parched) 7 parts, Ramulus Cinnamomi 8 parts, 7 parts, Radix Glycyrrhizae, Cortex Phellodendri 8 parts, Fructus Schisandrae Chinensis 7 parts, Herba Lycopi 6 parts, Radix Saposhnikoviae 4 parts, the Radix Angelicae Dahuricae 8 parts.
The preparation method of above-mentioned Chinese medicine decoction, preparation process is as follows:
(1) Semen Cuscutae, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are soaked 2.5 hours, water consumption is 4 times of crude drug gross weight;
(2) Semen Cuscutae after immersion, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are decocted with water 70 minutes, water consumption is 3 times of crude drug gross weight, filters to get filtrate and medicinal residues;
(3) step (2) gained medicinal residues are decocted with water 50 minutes again, filter to get filtrate;
(4) by step (2) and the mixing of step (3) gained filtrate, sterile packaged, obtains Chinese medicine decoction.
model case three: poplar XX, female, 55 years old.Patient stops the time of menstruation more late, post menopausal sleep quality declines, evening difficulty falling asleep, wake up in the morning very early, and Depth of sleep is inadequate evening, there is a bit little sound also to be waken up with a start, and evening always have horrible nightmares, remove examination in hospital, doctor says it is cause menopause, some Western medicine are eaten, without positive effect.Take the present embodiment 4 gained Chinese medicine decoction, adopt potion every day, in sooner or later within 1 hour after meal, taking, 7 days courses for the treatment of.Take 21 days, patient sleeps's quality is improved, and bad dream reduces; Take 2 months, patient sleeps's quality significantly improves, and the mental status is improved; Continue to take 1 month, patient sleeps is normal, and self-induction is fully recovered.
embodiment 5improve the Chinese medicine decoction of menopausal women sleep quality, be prepared from (getting 25g for every part) by following main materials medicine: Semen Cuscutae 10 parts, Rhizoma Chuanxiong 9 parts, Concha Ostreae (calcined) 15 parts, the Radix Paeoniae Alba 12 parts, Herba Epimedii 12 parts, Ramulus Uncariae Cum Uncis 12 parts, Herba Leonuri 9 parts, Radix Scutellariae 9 parts, Semen Ziziphi Spinosae (parched) 6 parts, Ramulus Cinnamomi 6 parts, 6 parts, Radix Glycyrrhizae, Cortex Phellodendri 6 parts, Fructus Schisandrae Chinensis 6 parts, Herba Lycopi 5 parts, Radix Saposhnikoviae 3.5 parts, the Radix Angelicae Dahuricae 7 parts.
The preparation method of above-mentioned Chinese medicine decoction, preparation process is as follows:
(1) Semen Cuscutae, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are soaked 2 hours, water consumption is 3 times of crude drug gross weight;
(2) Semen Cuscutae after immersion, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are decocted with water 60 minutes, water consumption is 2.5 times of crude drug gross weight, filters to get filtrate and medicinal residues;
(3) step (2) gained medicinal residues are decocted with water 40 minutes again, filter to get filtrate;
(4) by step (2) and the mixing of step (3) gained filtrate, sterile packaged, obtains Chinese medicine decoction.
experimental example 1embodiment 5 gained improves the clinical practice of the Chinese medicine decoction of menopausal women sleep quality: in July, 2009-2011 year November, screen 300 patients in 10 hospitals.Before test 1 week, carry out Continuous Observation to this crowd, record symptom and change, 300 patients are divided into two large groups, experimental group and matched group at random, and experimental group uses embodiment 5 gained Chinese medicine decoction, every day twice, within 1 hour after meal, take in morning and evening every day.Matched group takes other medicines (conventional medication such as ANSHEN BUNAO YE, ANSHEN BUXIN WAN).Two groups was all 1 course for the treatment of with 7 days.Curative effect situation criterion: cure: sleep quality improves, sleep is normal, and the mental status takes a turn for the better; Effective: symptom alleviates, sleep quality is than front raising; Invalid: compared with before treatment, each side has no significant change.
Table 1: before and after two groups of treatments, Clinical symptom and sign evaluation situation compares
Note: above in table, sleep is normal, the mental status improves and life normal data is all taken the mean.
Result: before and after two groups of treatments, Clinical symptom and sign are evaluated situations and compared, and after treatment, two groups of patients, 2 curative effect indexs all make moderate progress, and experimental group improves successful is better than matched group.
Table 2: two groups of Clinical efficacy comparisons [example (%)]
| Group | Case load | Clinical cure | Effectively | Invalid | Cure rate | Total effective rate |
| Experimental group | 200 | 140 | 56 | 4 | 70% | 98% |
| Matched group | 100 | 29 | 47 | 24 | 29% | 76% |
Chinese medicine decoction of the present invention selects the medicines such as Semen Cuscutae, Rhizoma Chuanxiong, Ramulus Uncariae Cum Uncis, Semen Ziziphi Spinosae (parched), Fructus Schisandrae Chinensis, the Radix Angelicae Dahuricae to carry out compatibility, makes medicine produce synergism, can the more effective sleep quality improving menopausal women.As shown in Table 2, experimental group cure rate is 70%, and total effective rate is 98%; Matched group cure rate is 29%, and total effective rate is that 76%, two groups of Clinical efficacy comparisons show that experimental group curative effect is obviously better than matched group.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (6)
1. improve the preparation method of the Chinese medicine decoction of menopausal women sleep quality, it is characterized in that, take off the crude drug stating weight proportion: Semen Cuscutae 10 parts, Rhizoma Chuanxiong 9 parts, Concha Ostreae (calcined) 15 parts, the Radix Paeoniae Alba 12 parts, Herba Epimedii 12 parts, Ramulus Uncariae Cum Uncis 12 parts, Herba Leonuri 9 parts, Radix Scutellariae 9 parts, Semen Ziziphi Spinosae (parched) 6 parts, Ramulus Cinnamomi 6 parts, 6 parts, Radix Glycyrrhizae, Cortex Phellodendri 6 parts, Fructus Schisandrae Chinensis 6 parts, Herba Lycopi 5 parts, Radix Saposhnikoviae 3.5 parts, the Radix Angelicae Dahuricae 7 parts; Step is as follows:
(1) Semen Cuscutae, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are soaked 1.5-2.5 hour, water consumption is 2-4 times of crude drug gross weight;
(2) Semen Cuscutae after immersion, Rhizoma Chuanxiong, Concha Ostreae (calcined), the Radix Paeoniae Alba, Herba Epimedii, Ramulus Uncariae Cum Uncis, Herba Leonuri, Radix Scutellariae, Semen Ziziphi Spinosae (parched), Ramulus Cinnamomi, Radix Glycyrrhizae, Cortex Phellodendri, Fructus Schisandrae Chinensis, Herba Lycopi, Radix Saposhnikoviae and the Radix Angelicae Dahuricae are decocted with water 50-70 minute, water consumption is 2-3 times of crude drug gross weight, filters to get filtrate and medicinal residues;
(3) step (2) gained medicinal residues are decocted with water 30-50 minute again, filter to get filtrate;
(4) by step (2) and the mixing of step (3) gained filtrate, sterile packaged, obtains Chinese medicine decoction.
2. preparation method according to claim 1, is characterized in that, step (1) soaks 2 hours.
3. preparation method according to claim 1, is characterized in that, step (1) water consumption is 3 times of crude drug gross weight.
4. preparation method according to claim 1, is characterized in that, step (2) decocts with water 60 minutes.
5. preparation method according to claim 1, is characterized in that, step (2) water consumption is 2.5 times of crude drug gross weight.
6. preparation method according to claim 1, is characterized in that, step (3) decocts with water 40 minutes again.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1279090A (en) * | 1999-06-25 | 2001-01-10 | 刘永香 | Powdered medicine for conditioning viscera and whole body |
| CN103272136A (en) * | 2013-05-16 | 2013-09-04 | 孙红艳 | Traditional Chinese medicine for treating climacteric syndrome of women |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1279090A (en) * | 1999-06-25 | 2001-01-10 | 刘永香 | Powdered medicine for conditioning viscera and whole body |
| CN103272136A (en) * | 2013-05-16 | 2013-09-04 | 孙红艳 | Traditional Chinese medicine for treating climacteric syndrome of women |
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| Title |
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| 更年期失眠的辨治5法;朱丽红等;《新疆中医药》;20070225(第01期);第56-57页 * |
| 辨证治疗绝经前后诸症体会;马春芬等;《河南中医》;20111130(第11期);第1260-1261页 * |
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